Reviewer's report
Title:Giant flat adenomas of rectum successfully treated in two steps by
endoscopic submucosal dissection and endoscopic mucosal resection.
Version: 2Date:8 April 2010
Reviewer: Naoto Sakamoto
Reviewer's report:
Although authors answered some of our comments, they did not respond
adequately to the demands of the most important questionable point.
Authors described that they obtained the complete dissection of the polyp and
the complete histological evaluation from the piecemeal samples. However, they
still not have understood the definition of “complete dissection”. We cannot
believe that it is possible to obtain the complete histological evaluation from the
rugged ulcer after tumor resection, and anxious about the risk of over looking of
sm invasion or lymph-vascular invasions.
If authors would like to convince us, they should obtain the complete histological
evaluation. In addition, they have to demonstrate restructured histological
specimens reflecting macroscopic specimens in additional Figure.
Reviewer's report
Title:Giant flat adenomas of rectum successfully treated in two steps by
endoscopic submucosal dissection and endoscopic mucosal resection.
Version: 2Date:8 April 2010
Reviewer: Naoto Sakamoto
Reviewer's report:
Although authors answered some of our comments, they did not respond
adequately to the demands of the most important questionable point.
Authors described that they obtained the complete dissection of the polyp and
the complete histological evaluation from the piecemeal samples. However, they
still not have understood the definition of “complete dissection”. We cannot
believe that it is possible to obtain the complete histological evaluation from the
rugged ulcer after tumor resection, and anxious about the risk of over looking of
sm invasion or lymph-vascular invasions.
If authors would like to convince us, they should obtain the complete histological
evaluation. In addition, they have to demonstrate restructured histological
specimens reflecting macroscopic specimens in additional Figure.
Please review this paper.
user
Reviewer's report
Title:Giant flat adenomas of rectum successfully treated in two steps by
endoscopic submucosal dissection and endoscopic mucosal resection.
Version: 2Date:8 April 2010
Reviewer: Naoto Sakamoto
Reviewer's report:
Although authors answered some of our comments, they did not respond
adequately to the demands of the most important questionable point.
Authors described that they obtained the complete dissection of the polyp and
the complete histological evaluation from the piecemeal samples. However, they
still not have understood the definition of “complete dissection”. We cannot
believe that it is possible to obtain the complete histological evaluation from the
rugged ulcer after tumor resection, and anxious about the risk of over looking of
sm invasion or lymph-vascular invasions.
If authors would like to convince us, they should obtain the complete histological
evaluation. In addition, they have to demonstrate restructured histological
specimens reflecting macroscopic specimens in additional Figure.
assistant