Reviewer's report
Title:MiR-195 Affects Cell Migration and Cell Proliferation by Down-regulating
DIEXF in Hirschsprung's Disease
Version:1Date:12 March 2014
Reviewer: Aiwu Li
Reviewer's report:
Minor Essential Revisions
MiR-195 played a role in the pathogenesis of HSCR by down-regulated the level
of DIEXF, then a detailed function of DIEXF should be needed in this paper.
Enteric neural crest cells (ENCCs) migration disorder sometimes was related
with the abnormal extracellular matrix(EMC),so suppressing interference of EMC
is needed.
The sample size of 58 cases was not very enough for the analysis of Mi-RNA.
What the author did in this paper could not be regarded as a new pathogenesis
of HSCR, which could be regarded as a foundation for it.
Some grammatical mistakes should be modified.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
'I declare that I have no competing interests
Reviewer's report
Title:MiR-195 Affects Cell Migration and Cell Proliferation by Down-regulating
DIEXF in Hirschsprung's Disease
Version:1Date:12 March 2014
Reviewer: Aiwu Li
Reviewer's report:
Minor Essential Revisions
MiR-195 played a role in the pathogenesis of HSCR by down-regulated the level
of DIEXF, then a detailed function of DIEXF should be needed in this paper.
Enteric neural crest cells (ENCCs) migration disorder sometimes was related
with the abnormal extracellular matrix(EMC),so suppressing interference of EMC
is needed.
The sample size of 58 cases was not very enough for the analysis of Mi-RNA.
What the author did in this paper could not be regarded as a new pathogenesis
of HSCR, which could be regarded as a foundation for it.
Some grammatical mistakes should be modified.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
'I declare that I have no competing interests
Please review this paper.
user
Reviewer's report
Title:MiR-195 Affects Cell Migration and Cell Proliferation by Down-regulating
DIEXF in Hirschsprung's Disease
Version:1Date:12 March 2014
Reviewer: Aiwu Li
Reviewer's report:
Minor Essential Revisions
MiR-195 played a role in the pathogenesis of HSCR by down-regulated the level
of DIEXF, then a detailed function of DIEXF should be needed in this paper.
Enteric neural crest cells (ENCCs) migration disorder sometimes was related
with the abnormal extracellular matrix(EMC),so suppressing interference of EMC
is needed.
The sample size of 58 cases was not very enough for the analysis of Mi-RNA.
What the author did in this paper could not be regarded as a new pathogenesis
of HSCR, which could be regarded as a foundation for it.
Some grammatical mistakes should be modified.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
'I declare that I have no competing interests
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