Title: B3GNT7 regulates mucin O-glycosylation to alleviate colonic inflammation
Version: 2 Date: 08 Apr 2024
Reviewer's report:
The authors should include the importance of mucin O-glycosylation in cancers in the
Discussion section.
The authors should cite more articles describing the importance of mucin glycosylation and
B3GNT7, for example, MUC1 (important for inflammation) https://www.sciencedirect.com/
science/article/abs/pii/S0006291X02005533
https://pubmed.ncbi.nlm.nih.gov/31753595/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980628/
The authors should write in the Discussion section about the limitations of this study. There is
no validation using cell lines or mouse models.
Title: B3GNT7 regulates mucin O-glycosylation to alleviate colonic inflammation
Version: 2 Date: 08 Apr 2024
Reviewer's report:
The authors should include the importance of mucin O-glycosylation in cancers in the
Discussion section.
The authors should cite more articles describing the importance of mucin glycosylation and
B3GNT7, for example, MUC1 (important for inflammation) https://www.sciencedirect.com/
science/article/abs/pii/S0006291X02005533
https://pubmed.ncbi.nlm.nih.gov/31753595/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980628/
The authors should write in the Discussion section about the limitations of this study. There is
no validation using cell lines or mouse models.
Please review this paper.
user
Title: B3GNT7 regulates mucin O-glycosylation to alleviate colonic inflammation
Version: 2 Date: 08 Apr 2024
Reviewer's report:
The authors should include the importance of mucin O-glycosylation in cancers in the
Discussion section.
The authors should cite more articles describing the importance of mucin glycosylation and
B3GNT7, for example, MUC1 (important for inflammation) https://www.sciencedirect.com/
science/article/abs/pii/S0006291X02005533
https://pubmed.ncbi.nlm.nih.gov/31753595/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980628/
The authors should write in the Discussion section about the limitations of this study. There is
no validation using cell lines or mouse models.
assistant