Reviewer's report
Title:Hepatocellular carcinoma associated with Budd-Chiari syndrome: imaging
features and transcatheter arterial chemoembolization
Version: 2Date:23 January 2013
Reviewer: Aurelie Plessier
Reviewer's report:
Major revisions:
The authors report 5% of HCC in a retrospective serie of 246 patients. Little is
known on HCC prevalence, screening tools and treatments in BCS, and this
study is informative on these 3 points. Nevertheless, the authors scarcely
describe the methodology of nodules and HCC screening in the whole serie. How
many patients had an MRI or CT scan on the 246 to detect enhanced nodules?
how can we be sure that patients with benign nodules had true benign nodules
when we clearly know that distinction between begnign and HCC is the real
difficulty in this setting. What was the median follow up of patients with bengn
nodules?
Minor revisions
Spelling mistakes:
P 3
P 4
P7
P13
Table 1
line 3 is Not very informative
Level of interest: An article of importance in its field
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests
Reviewer's report
Title:Hepatocellular carcinoma associated with Budd-Chiari syndrome: imaging
features and transcatheter arterial chemoembolization
Version: 2Date:23 January 2013
Reviewer: Aurelie Plessier
Reviewer's report:
Major revisions:
The authors report 5% of HCC in a retrospective serie of 246 patients. Little is
known on HCC prevalence, screening tools and treatments in BCS, and this
study is informative on these 3 points. Nevertheless, the authors scarcely
describe the methodology of nodules and HCC screening in the whole serie. How
many patients had an MRI or CT scan on the 246 to detect enhanced nodules?
how can we be sure that patients with benign nodules had true benign nodules
when we clearly know that distinction between begnign and HCC is the real
difficulty in this setting. What was the median follow up of patients with bengn
nodules?
Minor revisions
Spelling mistakes:
P 3
P 4
P7
P13
Table 1
line 3 is Not very informative
Level of interest: An article of importance in its field
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests
Please review this paper.
user
Reviewer's report
Title:Hepatocellular carcinoma associated with Budd-Chiari syndrome: imaging
features and transcatheter arterial chemoembolization
Version: 2Date:23 January 2013
Reviewer: Aurelie Plessier
Reviewer's report:
Major revisions:
The authors report 5% of HCC in a retrospective serie of 246 patients. Little is
known on HCC prevalence, screening tools and treatments in BCS, and this
study is informative on these 3 points. Nevertheless, the authors scarcely
describe the methodology of nodules and HCC screening in the whole serie. How
many patients had an MRI or CT scan on the 246 to detect enhanced nodules?
how can we be sure that patients with benign nodules had true benign nodules
when we clearly know that distinction between begnign and HCC is the real
difficulty in this setting. What was the median follow up of patients with bengn
nodules?
Minor revisions
Spelling mistakes:
P 3
P 4
P7
P13
Table 1
line 3 is Not very informative
Level of interest: An article of importance in its field
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests
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