Title: Association and Temporal Sequence of Pneumonia and Gastrointestinal Bleeding after
Acute Ischemic Stroke
Version: 1 Date: 06 Jun 2024
Reviewer:  Vikramjeet Singh
Reviewer's report:
The study presented by Zhang et al. is very interesting and highlights the association of co-
morbidities such as pneumonia and gastrointestinal bleeding with ischemic stroke conditions in
patients. I have a few suggestions to add further information to the manuscript to increase its
impact and readership.
1)  In the discussion section, it will be important to discuss the major causes of post-stroke
pneumonia namely immunosuppression, and how this might be treated in the future (https://
www.nature.com/articles/s44161-024-00462-8).
2) Please provide an example of anti-platelet and anti-coagulant therapies in the patients in the
manuscript text (In addition to the tables).
3) Please explain what were the prophylactic interventions to prevent GIB.
4) Elaborate PNE in the legend of Figure 2.
5) I will suggest language proofreading.
Title: Association and Temporal Sequence of Pneumonia and Gastrointestinal Bleeding after
Acute Ischemic Stroke
Version: 1 Date: 06 Jun 2024
Reviewer:  Vikramjeet Singh
Reviewer's report:
The study presented by Zhang et al. is very interesting and highlights the association of co-
morbidities such as pneumonia and gastrointestinal bleeding with ischemic stroke conditions in
patients. I have a few suggestions to add further information to the manuscript to increase its
impact and readership.
1)  In the discussion section, it will be important to discuss the major causes of post-stroke
pneumonia namely immunosuppression, and how this might be treated in the future (https://
www.nature.com/articles/s44161-024-00462-8).
2) Please provide an example of anti-platelet and anti-coagulant therapies in the patients in the
manuscript text (In addition to the tables).
3) Please explain what were the prophylactic interventions to prevent GIB.
4) Elaborate PNE in the legend of Figure 2.
5) I will suggest language proofreading.
Please review this paper.
user
Title: Association and Temporal Sequence of Pneumonia and Gastrointestinal Bleeding after
Acute Ischemic Stroke
Version: 1 Date: 06 Jun 2024
Reviewer:  Vikramjeet Singh
Reviewer's report:
The study presented by Zhang et al. is very interesting and highlights the association of co-
morbidities such as pneumonia and gastrointestinal bleeding with ischemic stroke conditions in
patients. I have a few suggestions to add further information to the manuscript to increase its
impact and readership.
1)  In the discussion section, it will be important to discuss the major causes of post-stroke
pneumonia namely immunosuppression, and how this might be treated in the future (https://
www.nature.com/articles/s44161-024-00462-8).
2) Please provide an example of anti-platelet and anti-coagulant therapies in the patients in the
manuscript text (In addition to the tables).
3) Please explain what were the prophylactic interventions to prevent GIB.
4) Elaborate PNE in the legend of Figure 2.
5) I will suggest language proofreading.
assistant