Reviewer ’s report  
 
Title:  A case of ectopic pancreas in the ileum presenting as obscure gastrointestinal bleeding and 
abdominal pain  
 
Version: 1 Date: 15 Jan 2019 
 
Reviewer:  Jianfeng  Yang  
 
Reviewer’s report:  
 
The authors describe a case of ectopic pancreas in the ileum presenting as obscure 
gastrointestinal bleeding and episodes of abdominal pai n. The case is interesting, however, it's 
not the first one to report the association between gastrointestinal bleeding and ectopic pancreas 
located in the ileum. Besides, some points should be raised from the authors:  
 
--In abstract "59 -year-old man had 9 months history of intermittent melena", but in case 
presentation "A 59 -year-old man had 3 months history of intermittent melena", please clarify.  
 
-There are some spelling and grammatical mistakes in the manuscript, which needs correction.  
 
-The title is no t very suitable for this case, its scope is too broad and not attractive.  
 
-There are several case reports about obscure gastrointestinal bleeding caused by ectopic 
pancreas, such as Korean J Gastroenterol. 2013; 62(3):165 -8., Quant Imaging Med Surg.2015; 
5(5):783 -6. and Clin Endosc. 2012; 45(3):194 -7. These studies should be summarized and 
presented in the Discussion section.  
 
-Discussion should be enriched by discussing clinical presentation, investigations, treatment, 
prognosis and complications as availa ble in the literature about ectopic pancreas.  
 
Recommendation: Major Revision or Rejection  
 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
Yes 
 
Does the  work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
No 
 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in the manuscript or would you recommend an 
additional statistical review?  
If an additional statistical review is recommended, please specify what aspects require further 
assessment in your comments to the editors.  
 
Not relevant to this manuscript  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Needs some lan guage corrections before being published  
 
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following q uestions:  
 
1. Have you in the past five years received reimbursements, fees, funding, or salary from an 
organisation that may in any way gain or lose financially from the publication of this 
manuscript, either now or in the future?  
 
2. Do you hold any stocks or shares in an organisation that may in any way gain or lose 
financially from the publication of this manuscript, either now or in the future?  
 
3. Do you hold or are you currently applying for any patents relating to the content of the 
manuscript?  
 
4. Have you received reimbursements, fees, funding, or salary from an organization that 
holds or has applied for patents relating to the content of the manuscript?  
 
5. Do you have any other financial competing interests?  
 
6. Do you have any non -financial competing interests  in relation to this paper?  
 
If you can answer no to all of the above, write 'I declare that I have no competing interests' 
below. If your reply is yes to any, please give details below.  
 
'I declare that I have no competing interests  
 
I agree to the open peer review policy of the  journal. I understand that my name will be included 
on my report to the authors and, if the manuscript is accepted for publication, my named report 
including any attachments I upload will be posted on the website along with the authors' 
responses. I agree  for my report to be made available under an Open Access Creative Commons 
CC-BY license ( http://creativecommons.org/licenses/by/4.0/ ). I understand that any comments 
which I do not wish to be includ ed in my named report can be included as confidential comments 
to the editors, which will not be published.  
I agree to the open peer review policy of the journal  
Reviewer ’s report  
 
Title:  A case of ectopic pancreas in the ileum presenting as obscure gastrointestinal bleeding and 
abdominal pain  
 
Version: 1 Date: 15 Jan 2019 
 
Reviewer:  Jianfeng  Yang  
 
Reviewer’s report:  
 
The authors describe a case of ectopic pancreas in the ileum presenting as obscure 
gastrointestinal bleeding and episodes of abdominal pai n. The case is interesting, however, it's 
not the first one to report the association between gastrointestinal bleeding and ectopic pancreas 
located in the ileum. Besides, some points should be raised from the authors:  
 
--In abstract "59 -year-old man had 9 months history of intermittent melena", but in case 
presentation "A 59 -year-old man had 3 months history of intermittent melena", please clarify.  
 
-There are some spelling and grammatical mistakes in the manuscript, which needs correction.  
 
-The title is no t very suitable for this case, its scope is too broad and not attractive.  
 
-There are several case reports about obscure gastrointestinal bleeding caused by ectopic 
pancreas, such as Korean J Gastroenterol. 2013; 62(3):165 -8., Quant Imaging Med Surg.2015; 
5(5):783 -6. and Clin Endosc. 2012; 45(3):194 -7. These studies should be summarized and 
presented in the Discussion section.  
 
-Discussion should be enriched by discussing clinical presentation, investigations, treatment, 
prognosis and complications as availa ble in the literature about ectopic pancreas.  
 
Recommendation: Major Revision or Rejection  
 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
Yes 
 
Does the  work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
No 
 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in the manuscript or would you recommend an 
additional statistical review?  
If an additional statistical review is recommended, please specify what aspects require further 
assessment in your comments to the editors.  
 
Not relevant to this manuscript  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Needs some lan guage corrections before being published  
 
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following q uestions:  
 
1. Have you in the past five years received reimbursements, fees, funding, or salary from an 
organisation that may in any way gain or lose financially from the publication of this 
manuscript, either now or in the future?  
 
2. Do you hold any stocks or shares in an organisation that may in any way gain or lose 
financially from the publication of this manuscript, either now or in the future?  
 
3. Do you hold or are you currently applying for any patents relating to the content of the 
manuscript?  
 
4. Have you received reimbursements, fees, funding, or salary from an organization that 
holds or has applied for patents relating to the content of the manuscript?  
 
5. Do you have any other financial competing interests?  
 
6. Do you have any non -financial competing interests  in relation to this paper?  
 
If you can answer no to all of the above, write 'I declare that I have no competing interests' 
below. If your reply is yes to any, please give details below.  
 
'I declare that I have no competing interests  
 
I agree to the open peer review policy of the  journal. I understand that my name will be included 
on my report to the authors and, if the manuscript is accepted for publication, my named report 
including any attachments I upload will be posted on the website along with the authors' 
responses. I agree  for my report to be made available under an Open Access Creative Commons 
CC-BY license ( http://creativecommons.org/licenses/by/4.0/ ). I understand that any comments 
which I do not wish to be includ ed in my named report can be included as confidential comments 
to the editors, which will not be published.  
I agree to the open peer review policy of the journal  
Please review this paper.
user
Reviewer ’s report  
 
Title:  A case of ectopic pancreas in the ileum presenting as obscure gastrointestinal bleeding and 
abdominal pain  
 
Version: 1 Date: 15 Jan 2019 
 
Reviewer:  Jianfeng  Yang  
 
Reviewer’s report:  
 
The authors describe a case of ectopic pancreas in the ileum presenting as obscure 
gastrointestinal bleeding and episodes of abdominal pai n. The case is interesting, however, it's 
not the first one to report the association between gastrointestinal bleeding and ectopic pancreas 
located in the ileum. Besides, some points should be raised from the authors:  
 
--In abstract "59 -year-old man had 9 months history of intermittent melena", but in case 
presentation "A 59 -year-old man had 3 months history of intermittent melena", please clarify.  
 
-There are some spelling and grammatical mistakes in the manuscript, which needs correction.  
 
-The title is no t very suitable for this case, its scope is too broad and not attractive.  
 
-There are several case reports about obscure gastrointestinal bleeding caused by ectopic 
pancreas, such as Korean J Gastroenterol. 2013; 62(3):165 -8., Quant Imaging Med Surg.2015; 
5(5):783 -6. and Clin Endosc. 2012; 45(3):194 -7. These studies should be summarized and 
presented in the Discussion section.  
 
-Discussion should be enriched by discussing clinical presentation, investigations, treatment, 
prognosis and complications as availa ble in the literature about ectopic pancreas.  
 
Recommendation: Major Revision or Rejection  
 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
Yes 
 
Does the  work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
No 
 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in the manuscript or would you recommend an 
additional statistical review?  
If an additional statistical review is recommended, please specify what aspects require further 
assessment in your comments to the editors.  
 
Not relevant to this manuscript  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Needs some lan guage corrections before being published  
 
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following q uestions:  
 
1. Have you in the past five years received reimbursements, fees, funding, or salary from an 
organisation that may in any way gain or lose financially from the publication of this 
manuscript, either now or in the future?  
 
2. Do you hold any stocks or shares in an organisation that may in any way gain or lose 
financially from the publication of this manuscript, either now or in the future?  
 
3. Do you hold or are you currently applying for any patents relating to the content of the 
manuscript?  
 
4. Have you received reimbursements, fees, funding, or salary from an organization that 
holds or has applied for patents relating to the content of the manuscript?  
 
5. Do you have any other financial competing interests?  
 
6. Do you have any non -financial competing interests  in relation to this paper?  
 
If you can answer no to all of the above, write 'I declare that I have no competing interests' 
below. If your reply is yes to any, please give details below.  
 
'I declare that I have no competing interests  
 
I agree to the open peer review policy of the  journal. I understand that my name will be included 
on my report to the authors and, if the manuscript is accepted for publication, my named report 
including any attachments I upload will be posted on the website along with the authors' 
responses. I agree  for my report to be made available under an Open Access Creative Commons 
CC-BY license ( http://creativecommons.org/licenses/by/4.0/ ). I understand that any comments 
which I do not wish to be includ ed in my named report can be included as confidential comments 
to the editors, which will not be published.  
I agree to the open peer review policy of the journal  
assistant