Title: Clinical characteristics of Dieulafoy’s Lesion in the Small Bowel Diagnosed and Treated
by Double-Balloon Endoscopy
Version: 4 Date: 08 May 2023
Reviewer's report:
Thank you for the opportunity to review this manuscript entitled “Clinical characteristics of
Dieulafoy’s Lesion in the Small Bowel Diagnosed and Treated by Double-Balloon Endoscopy”
again. The authors investigated the clinical characteristics of Dieulafoy’s lesion (DL) in the small
bowel by double-balloon endoscopy and the factors to predict DL in obscure gastrointestinal
bleeding. They concluded that DL is likely to have the failed initial diagnosis in case with
two or more episodes of hematochezia and difficulty to predict bleeding from DL in obscure
gastrointestinal bleeding.
Major comments:
1) Definition of hematochezia and inclusion criteria of double-balloon endoscopy (according to
physician’s decision) are too subjective and obscure. Hence, frequency of hematochezia should
not be included in the factor to predict DL. Please show more objective data, or the result of
this manuscript cannot be generalized.
2) I think that conclusion of this study is less impressive for daily clinical practice unless they
could find any predictors to have definite diagnosis as DL and also factors associated with re-
bleeding.
Title: Clinical characteristics of Dieulafoy’s Lesion in the Small Bowel Diagnosed and Treated
by Double-Balloon Endoscopy
Version: 4 Date: 08 May 2023
Reviewer's report:
Thank you for the opportunity to review this manuscript entitled “Clinical characteristics of
Dieulafoy’s Lesion in the Small Bowel Diagnosed and Treated by Double-Balloon Endoscopy”
again. The authors investigated the clinical characteristics of Dieulafoy’s lesion (DL) in the small
bowel by double-balloon endoscopy and the factors to predict DL in obscure gastrointestinal
bleeding. They concluded that DL is likely to have the failed initial diagnosis in case with
two or more episodes of hematochezia and difficulty to predict bleeding from DL in obscure
gastrointestinal bleeding.
Major comments:
1) Definition of hematochezia and inclusion criteria of double-balloon endoscopy (according to
physician’s decision) are too subjective and obscure. Hence, frequency of hematochezia should
not be included in the factor to predict DL. Please show more objective data, or the result of
this manuscript cannot be generalized.
2) I think that conclusion of this study is less impressive for daily clinical practice unless they
could find any predictors to have definite diagnosis as DL and also factors associated with re-
bleeding.
Please review this paper.
user
Title: Clinical characteristics of Dieulafoy’s Lesion in the Small Bowel Diagnosed and Treated
by Double-Balloon Endoscopy
Version: 4 Date: 08 May 2023
Reviewer's report:
Thank you for the opportunity to review this manuscript entitled “Clinical characteristics of
Dieulafoy’s Lesion in the Small Bowel Diagnosed and Treated by Double-Balloon Endoscopy”
again. The authors investigated the clinical characteristics of Dieulafoy’s lesion (DL) in the small
bowel by double-balloon endoscopy and the factors to predict DL in obscure gastrointestinal
bleeding. They concluded that DL is likely to have the failed initial diagnosis in case with
two or more episodes of hematochezia and difficulty to predict bleeding from DL in obscure
gastrointestinal bleeding.
Major comments:
1) Definition of hematochezia and inclusion criteria of double-balloon endoscopy (according to
physician’s decision) are too subjective and obscure. Hence, frequency of hematochezia should
not be included in the factor to predict DL. Please show more objective data, or the result of
this manuscript cannot be generalized.
2) I think that conclusion of this study is less impressive for daily clinical practice unless they
could find any predictors to have definite diagnosis as DL and also factors associated with re-
bleeding.
assistant