Title: Good performance of monoclonal antibody-based stool H. pylori antigen tests in acute
nonvariceal upper gastrointestinal bleeding patients
Version: 4 Date: 13 May 2025
Reviewer's report:
Introduction
The introduction provides valuable background information on H. pylori testing; however, the
statement of the problem should be more explicit. Specifically, the authors should clearly explain
the rationale for combining the two tests and highlight the significance of this approach in
clinical practice. Providing a stronger justification will enhance the reader’s understanding of
the study’s importance.
Study Methods
Several key methodological details need further clarification:
- The study design should be explicitly stated.
- Information regarding patient age distribution and stratification should be included.
- The authors should explain how the sample size was calculated and provide justification for
the chosen approach.
- The inclusion and exclusion criteria must be clearly outlined to ensure transparency in patient
selection.
Discussion
The discussion should begin with an analysis of the study’s own results before comparing them
to findings from other studies. This will allow for a more structured and logical progression of
argumentation, ensuring the results are contextualized effectively within existing literature.
Title: Good performance of monoclonal antibody-based stool H. pylori antigen tests in acute
nonvariceal upper gastrointestinal bleeding patients
Version: 4 Date: 13 May 2025
Reviewer's report:
Introduction
The introduction provides valuable background information on H. pylori testing; however, the
statement of the problem should be more explicit. Specifically, the authors should clearly explain
the rationale for combining the two tests and highlight the significance of this approach in
clinical practice. Providing a stronger justification will enhance the reader’s understanding of
the study’s importance.
Study Methods
Several key methodological details need further clarification:
- The study design should be explicitly stated.
- Information regarding patient age distribution and stratification should be included.
- The authors should explain how the sample size was calculated and provide justification for
the chosen approach.
- The inclusion and exclusion criteria must be clearly outlined to ensure transparency in patient
selection.
Discussion
The discussion should begin with an analysis of the study’s own results before comparing them
to findings from other studies. This will allow for a more structured and logical progression of
argumentation, ensuring the results are contextualized effectively within existing literature.
Please review this paper.
user
Title: Good performance of monoclonal antibody-based stool H. pylori antigen tests in acute
nonvariceal upper gastrointestinal bleeding patients
Version: 4 Date: 13 May 2025
Reviewer's report:
Introduction
The introduction provides valuable background information on H. pylori testing; however, the
statement of the problem should be more explicit. Specifically, the authors should clearly explain
the rationale for combining the two tests and highlight the significance of this approach in
clinical practice. Providing a stronger justification will enhance the reader’s understanding of
the study’s importance.
Study Methods
Several key methodological details need further clarification:
- The study design should be explicitly stated.
- Information regarding patient age distribution and stratification should be included.
- The authors should explain how the sample size was calculated and provide justification for
the chosen approach.
- The inclusion and exclusion criteria must be clearly outlined to ensure transparency in patient
selection.
Discussion
The discussion should begin with an analysis of the study’s own results before comparing them
to findings from other studies. This will allow for a more structured and logical progression of
argumentation, ensuring the results are contextualized effectively within existing literature.
assistant