Reviewer's report
Title:Small intestinal bacterial overgrowth in irritable bowel syndrome: are there
any predictors?
Version: 1Date:2 February 2009
Reviewer: Mark Pimentel
Reviewer's report:
In the manuscript by Reddymasu, et al, the authors further delineate the
association between SIBO and IBS. More specifically, the authors find that sex
and age are major determinants of the prevalence of SIBO.
The study has limited data and is small in presentation. However, the data are
vitally important in one way. Recently, a paper speculated that since many IBS
patients are on proton pump inhibitor, that the PPI is affecting the result or even
causing SIBO. While this was speculation, this study answers this question. Thus
even more important than age and sex is this relationship. This needs to be
expounded in the manuscript and included in the discussion.
Perhaps a figure would also be helpful rather than data in a paragraph to make
the paper more interesting.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Reviewer's report
Title:Small intestinal bacterial overgrowth in irritable bowel syndrome: are there
any predictors?
Version: 1Date:2 February 2009
Reviewer: Mark Pimentel
Reviewer's report:
In the manuscript by Reddymasu, et al, the authors further delineate the
association between SIBO and IBS. More specifically, the authors find that sex
and age are major determinants of the prevalence of SIBO.
The study has limited data and is small in presentation. However, the data are
vitally important in one way. Recently, a paper speculated that since many IBS
patients are on proton pump inhibitor, that the PPI is affecting the result or even
causing SIBO. While this was speculation, this study answers this question. Thus
even more important than age and sex is this relationship. This needs to be
expounded in the manuscript and included in the discussion.
Perhaps a figure would also be helpful rather than data in a paragraph to make
the paper more interesting.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Please review this paper.
user
Reviewer's report
Title:Small intestinal bacterial overgrowth in irritable bowel syndrome: are there
any predictors?
Version: 1Date:2 February 2009
Reviewer: Mark Pimentel
Reviewer's report:
In the manuscript by Reddymasu, et al, the authors further delineate the
association between SIBO and IBS. More specifically, the authors find that sex
and age are major determinants of the prevalence of SIBO.
The study has limited data and is small in presentation. However, the data are
vitally important in one way. Recently, a paper speculated that since many IBS
patients are on proton pump inhibitor, that the PPI is affecting the result or even
causing SIBO. While this was speculation, this study answers this question. Thus
even more important than age and sex is this relationship. This needs to be
expounded in the manuscript and included in the discussion.
Perhaps a figure would also be helpful rather than data in a paragraph to make
the paper more interesting.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
assistant