Title: Survival analysis and individualized prediction of survival benefit for pancreatic signet
ring cell carcinoma: A population study based on the SEER database
Version: 2 Date: 11 Nov 2022
Reviewer's report:
Very interesting study on an important topic. I have the following concerns:
1) Like all SEER studies, this analysis lacks of granularity of data and this major limitation
should be commented in the Discussion
2)  In the KM curves, i would like to see shorted time periods (not every 50 months....)
3) The authors should comment some potential non-surgical interventional therapies for this
neoplasm, citing similar examples in PDAC (PMID: 27356212)
Title: Survival analysis and individualized prediction of survival benefit for pancreatic signet
ring cell carcinoma: A population study based on the SEER database
Version: 2 Date: 11 Nov 2022
Reviewer's report:
Very interesting study on an important topic. I have the following concerns:
1) Like all SEER studies, this analysis lacks of granularity of data and this major limitation
should be commented in the Discussion
2)  In the KM curves, i would like to see shorted time periods (not every 50 months....)
3) The authors should comment some potential non-surgical interventional therapies for this
neoplasm, citing similar examples in PDAC (PMID: 27356212)
Please review this paper.
user
Title: Survival analysis and individualized prediction of survival benefit for pancreatic signet
ring cell carcinoma: A population study based on the SEER database
Version: 2 Date: 11 Nov 2022
Reviewer's report:
Very interesting study on an important topic. I have the following concerns:
1) Like all SEER studies, this analysis lacks of granularity of data and this major limitation
should be commented in the Discussion
2)  In the KM curves, i would like to see shorted time periods (not every 50 months....)
3) The authors should comment some potential non-surgical interventional therapies for this
neoplasm, citing similar examples in PDAC (PMID: 27356212)
assistant