Title: A survey on the current status of Helicobacter pylori infection in households in Hainan
Province, China
Version: 1 Date: 13 Aug 2023
Reviewer's report:
The authors assessed the prevalence of Helicobacter pylori (Hp) infection at the household level
in Hainan Province and identify the factors that contribute to its spread. A total of 421 families,
comprising 1355 individuals, were tested for Hp infection across five cities in Hainan Province
between July 2021 and April 2022. They concluded that Hp infection was prevalent among
Hainan families, and interaction with infected family members may be the primary cause of
transmission.
The paper is interesting and written well. This paper may be one of the crucial pieces of evidence
for Hp infection in China. However, the following points should be addressed.
Major
1. In such kind of study, the selection method of the target population is one of the important
points. The authors should describe the method in detail.
2. In this study, paternal infection and maternal infection were risk factors for child infection,
with ORs of 2.93 (1.29-6.62) and 2.51 (1.07-5.89), respectively. This is an exciting point. As
the authors described, maternal infection has been reported to be one of the risk factors. Why
paternal infection is a more vital risk factor than maternal infection in the present study? The
authors should discuss this point.
3. The limitations of this study should be addressed.
Minor
1. Title and L3, P2
…in Hainan Province: …in Hainan Province, China
2. In the Methods of Abstract section, the authors should describe the questionnaire items briefly.
3. The order of the table should be changed. In the present manuscript, the order is Table 1,
3, then 2.
4. L2, P8
#100,000: #100,000 yuan
5. L2 below the bottom, P4
Helicobacter pylori (Hp): Hp
Title: A survey on the current status of Helicobacter pylori infection in households in Hainan
Province, China
Version: 1 Date: 13 Aug 2023
Reviewer's report:
The authors assessed the prevalence of Helicobacter pylori (Hp) infection at the household level
in Hainan Province and identify the factors that contribute to its spread. A total of 421 families,
comprising 1355 individuals, were tested for Hp infection across five cities in Hainan Province
between July 2021 and April 2022. They concluded that Hp infection was prevalent among
Hainan families, and interaction with infected family members may be the primary cause of
transmission.
The paper is interesting and written well. This paper may be one of the crucial pieces of evidence
for Hp infection in China. However, the following points should be addressed.
Major
1. In such kind of study, the selection method of the target population is one of the important
points. The authors should describe the method in detail.
2. In this study, paternal infection and maternal infection were risk factors for child infection,
with ORs of 2.93 (1.29-6.62) and 2.51 (1.07-5.89), respectively. This is an exciting point. As
the authors described, maternal infection has been reported to be one of the risk factors. Why
paternal infection is a more vital risk factor than maternal infection in the present study? The
authors should discuss this point.
3. The limitations of this study should be addressed.
Minor
1. Title and L3, P2
…in Hainan Province: …in Hainan Province, China
2. In the Methods of Abstract section, the authors should describe the questionnaire items briefly.
3. The order of the table should be changed. In the present manuscript, the order is Table 1,
3, then 2.
4. L2, P8
#100,000: #100,000 yuan
5. L2 below the bottom, P4
Helicobacter pylori (Hp): Hp
Please review this paper.
user
Title: A survey on the current status of Helicobacter pylori infection in households in Hainan
Province, China
Version: 1 Date: 13 Aug 2023
Reviewer's report:
The authors assessed the prevalence of Helicobacter pylori (Hp) infection at the household level
in Hainan Province and identify the factors that contribute to its spread. A total of 421 families,
comprising 1355 individuals, were tested for Hp infection across five cities in Hainan Province
between July 2021 and April 2022. They concluded that Hp infection was prevalent among
Hainan families, and interaction with infected family members may be the primary cause of
transmission.
The paper is interesting and written well. This paper may be one of the crucial pieces of evidence
for Hp infection in China. However, the following points should be addressed.
Major
1. In such kind of study, the selection method of the target population is one of the important
points. The authors should describe the method in detail.
2. In this study, paternal infection and maternal infection were risk factors for child infection,
with ORs of 2.93 (1.29-6.62) and 2.51 (1.07-5.89), respectively. This is an exciting point. As
the authors described, maternal infection has been reported to be one of the risk factors. Why
paternal infection is a more vital risk factor than maternal infection in the present study? The
authors should discuss this point.
3. The limitations of this study should be addressed.
Minor
1. Title and L3, P2
…in Hainan Province: …in Hainan Province, China
2. In the Methods of Abstract section, the authors should describe the questionnaire items briefly.
3. The order of the table should be changed. In the present manuscript, the order is Table 1,
3, then 2.
4. L2, P8
#100,000: #100,000 yuan
5. L2 below the bottom, P4
Helicobacter pylori (Hp): Hp
assistant