Title: Endoscopic features and clinical course of patients with asymptomatic cecal ulcers
Version: 1 Date: 18 May 2022
Reviewer's report:
I think the idea of this paper is good. Cecal ulcers are occasional findings during colonoscopy,
and the clinical significance is not well-explored. From this paper and the findings, we might
set a workup mode when we find cecal ulcers incidentally. Most cecal ulcers appear to be
spontaneously resolved. For patients with larger ulcer sizes (more than 1cm), irregular-shaped
ulcers, the deformed appearance of involved folds, or terminal ileum involvement, we should
emphasize the possibility of underlying disease entity or the risk of disease progression in the
patients. Terminal ileum inspection should be done if a cecal ulcer was detected. Workup of
intestinal tuberculosis should be done since tuberculosis is still a problem in Taiwan. Paying
attention to inflammatory bowel disease is also important. Surveillance of colonoscopy and
focus on the development of tuberculosis, Crohn’s disease, and ulcerative colitis are highly
valuable if a cecal ulcer was incidentally found.
The most obvious limitation of this exam is the scarcity of cecal ulcers patient. Only 39 cases
were found to have cecal ulcers in 34036 exams. Such a condition makes you have problems
determining which parameters of cecal ulcers are important.
Title: Endoscopic features and clinical course of patients with asymptomatic cecal ulcers
Version: 1 Date: 18 May 2022
Reviewer's report:
I think the idea of this paper is good. Cecal ulcers are occasional findings during colonoscopy,
and the clinical significance is not well-explored. From this paper and the findings, we might
set a workup mode when we find cecal ulcers incidentally. Most cecal ulcers appear to be
spontaneously resolved. For patients with larger ulcer sizes (more than 1cm), irregular-shaped
ulcers, the deformed appearance of involved folds, or terminal ileum involvement, we should
emphasize the possibility of underlying disease entity or the risk of disease progression in the
patients. Terminal ileum inspection should be done if a cecal ulcer was detected. Workup of
intestinal tuberculosis should be done since tuberculosis is still a problem in Taiwan. Paying
attention to inflammatory bowel disease is also important. Surveillance of colonoscopy and
focus on the development of tuberculosis, Crohn’s disease, and ulcerative colitis are highly
valuable if a cecal ulcer was incidentally found.
The most obvious limitation of this exam is the scarcity of cecal ulcers patient. Only 39 cases
were found to have cecal ulcers in 34036 exams. Such a condition makes you have problems
determining which parameters of cecal ulcers are important.
Please review this paper.
user
Title: Endoscopic features and clinical course of patients with asymptomatic cecal ulcers
Version: 1 Date: 18 May 2022
Reviewer's report:
I think the idea of this paper is good. Cecal ulcers are occasional findings during colonoscopy,
and the clinical significance is not well-explored. From this paper and the findings, we might
set a workup mode when we find cecal ulcers incidentally. Most cecal ulcers appear to be
spontaneously resolved. For patients with larger ulcer sizes (more than 1cm), irregular-shaped
ulcers, the deformed appearance of involved folds, or terminal ileum involvement, we should
emphasize the possibility of underlying disease entity or the risk of disease progression in the
patients. Terminal ileum inspection should be done if a cecal ulcer was detected. Workup of
intestinal tuberculosis should be done since tuberculosis is still a problem in Taiwan. Paying
attention to inflammatory bowel disease is also important. Surveillance of colonoscopy and
focus on the development of tuberculosis, Crohn’s disease, and ulcerative colitis are highly
valuable if a cecal ulcer was incidentally found.
The most obvious limitation of this exam is the scarcity of cecal ulcers patient. Only 39 cases
were found to have cecal ulcers in 34036 exams. Such a condition makes you have problems
determining which parameters of cecal ulcers are important.
assistant