Title: To Verify the Biological Characteristics of Disulfidptosis Associated Gene ADORA2B
in Esophageal Cancer
Version: 2 Date: 29 Jan 2025
Reviewer's report:
Esophageal cancer is an aggressive malignant tumor. Statistics show that esophageal cancer has
claimed the lives of approximately 300,000 people worldwide. Many patients are diagnosed
as stage 3 or 4 when they visit a doctor; however, the prognosis may not be accurate because
the disease's early signs are not always evident. The gene ADORA2B may be important
in the diagnosis and prognosis of esophageal cancer, as adenosine (ADO) is implicated in
the proliferation and spread of many malignancies.The results of this investigation validate
ADORA2B as a potential therapeutic target and diagnostic biomarker. However,why is there a
significant difference in the effects of Si1 and Si2 on ECA109 cells in Figure 8B?
It's still the same issue, I hope the author can pay attention to it.
Title: To Verify the Biological Characteristics of Disulfidptosis Associated Gene ADORA2B
in Esophageal Cancer
Version: 2 Date: 29 Jan 2025
Reviewer's report:
Esophageal cancer is an aggressive malignant tumor. Statistics show that esophageal cancer has
claimed the lives of approximately 300,000 people worldwide. Many patients are diagnosed
as stage 3 or 4 when they visit a doctor; however, the prognosis may not be accurate because
the disease's early signs are not always evident. The gene ADORA2B may be important
in the diagnosis and prognosis of esophageal cancer, as adenosine (ADO) is implicated in
the proliferation and spread of many malignancies.The results of this investigation validate
ADORA2B as a potential therapeutic target and diagnostic biomarker. However,why is there a
significant difference in the effects of Si1 and Si2 on ECA109 cells in Figure 8B?
It's still the same issue, I hope the author can pay attention to it.
Please review this paper.
user
Title: To Verify the Biological Characteristics of Disulfidptosis Associated Gene ADORA2B
in Esophageal Cancer
Version: 2 Date: 29 Jan 2025
Reviewer's report:
Esophageal cancer is an aggressive malignant tumor. Statistics show that esophageal cancer has
claimed the lives of approximately 300,000 people worldwide. Many patients are diagnosed
as stage 3 or 4 when they visit a doctor; however, the prognosis may not be accurate because
the disease's early signs are not always evident. The gene ADORA2B may be important
in the diagnosis and prognosis of esophageal cancer, as adenosine (ADO) is implicated in
the proliferation and spread of many malignancies.The results of this investigation validate
ADORA2B as a potential therapeutic target and diagnostic biomarker. However,why is there a
significant difference in the effects of Si1 and Si2 on ECA109 cells in Figure 8B?
It's still the same issue, I hope the author can pay attention to it.
assistant