Title: Variations in TM6SF2, PCSK9 and PCSK7 genes and risk of hepatic steatosis after liver
transplantation: a cross-sectional study
Version: 8 Date: 03 Jun 2021
Reviewer's report:
Title: Variations in TM6SF2, PCSK9 and PCSK7 genes and risk of hepatic steatosis after liver
transplantation
In the revised manuscript, authors delivered to most of the proposed comments and suggestions
in order to improve their paper.
However, concerning the analysis illustrated in the first panel of Figure 1, since no observation
are included in the TT genotype Steatosis (-) group of patients, none statistical analysis should
be performed.
Authors should describe their findings regarding patients with TT genotype polymorphisms with
(5.4%) and without (0%) hepatic steatosis, rather than performing a statistical test, as counting
zero observations in one of two comparable groups, the statistical analysis does not offer any
additional benefit.
Title: Variations in TM6SF2, PCSK9 and PCSK7 genes and risk of hepatic steatosis after liver
transplantation: a cross-sectional study
Version: 8 Date: 03 Jun 2021
Reviewer's report:
Title: Variations in TM6SF2, PCSK9 and PCSK7 genes and risk of hepatic steatosis after liver
transplantation
In the revised manuscript, authors delivered to most of the proposed comments and suggestions
in order to improve their paper.
However, concerning the analysis illustrated in the first panel of Figure 1, since no observation
are included in the TT genotype Steatosis (-) group of patients, none statistical analysis should
be performed.
Authors should describe their findings regarding patients with TT genotype polymorphisms with
(5.4%) and without (0%) hepatic steatosis, rather than performing a statistical test, as counting
zero observations in one of two comparable groups, the statistical analysis does not offer any
additional benefit.
Please review this paper.
user
Title: Variations in TM6SF2, PCSK9 and PCSK7 genes and risk of hepatic steatosis after liver
transplantation: a cross-sectional study
Version: 8 Date: 03 Jun 2021
Reviewer's report:
Title: Variations in TM6SF2, PCSK9 and PCSK7 genes and risk of hepatic steatosis after liver
transplantation
In the revised manuscript, authors delivered to most of the proposed comments and suggestions
in order to improve their paper.
However, concerning the analysis illustrated in the first panel of Figure 1, since no observation
are included in the TT genotype Steatosis (-) group of patients, none statistical analysis should
be performed.
Authors should describe their findings regarding patients with TT genotype polymorphisms with
(5.4%) and without (0%) hepatic steatosis, rather than performing a statistical test, as counting
zero observations in one of two comparable groups, the statistical analysis does not offer any
additional benefit.
assistant