Title: Increased expression of NOP14 is associated with improved prognosis due to immune
regulation in colorectal cancer
Version: 1 Date: 22 Mar 2022
Reviewer's report:
1# In Fig. 4A, well known prognostic factors of CRC, such as sidedness, pathological
differentiation, and staging have not been sufficiently analyzed. A multivariate analysis
including those factors should be performed.
2# Fig 4C; The contribution to prognosis is much larger in the T stage and N stage, compared
to NOP14 expression. It is supposed to predict the prognosis sufficiently even if a nomogram
that does not include NOP14 is used.
3#  Fig. 3B, C, D; There are many censored cases, and the number of patients followed for 50
months is only 1/10 of the total.
Title: Increased expression of NOP14 is associated with improved prognosis due to immune
regulation in colorectal cancer
Version: 1 Date: 22 Mar 2022
Reviewer's report:
1# In Fig. 4A, well known prognostic factors of CRC, such as sidedness, pathological
differentiation, and staging have not been sufficiently analyzed. A multivariate analysis
including those factors should be performed.
2# Fig 4C; The contribution to prognosis is much larger in the T stage and N stage, compared
to NOP14 expression. It is supposed to predict the prognosis sufficiently even if a nomogram
that does not include NOP14 is used.
3#  Fig. 3B, C, D; There are many censored cases, and the number of patients followed for 50
months is only 1/10 of the total.
Please review this paper.
user
Title: Increased expression of NOP14 is associated with improved prognosis due to immune
regulation in colorectal cancer
Version: 1 Date: 22 Mar 2022
Reviewer's report:
1# In Fig. 4A, well known prognostic factors of CRC, such as sidedness, pathological
differentiation, and staging have not been sufficiently analyzed. A multivariate analysis
including those factors should be performed.
2# Fig 4C; The contribution to prognosis is much larger in the T stage and N stage, compared
to NOP14 expression. It is supposed to predict the prognosis sufficiently even if a nomogram
that does not include NOP14 is used.
3#  Fig. 3B, C, D; There are many censored cases, and the number of patients followed for 50
months is only 1/10 of the total.
assistant