Title: Clinical and imaging features Preoperative evaluation of histological grade and
microvascular infiltration of hepatocellular carcinoma
Version: 1 Date: 01 Jun 2022
Reviewer's report:
To the authors:
“Clinical and imaging features Preoperative evaluation of histological grade and microvascular
infiltration of hepatocellular carcinoma”
My comments are as follows.
1. Please unify the font in Table 3.
2. How did you judge whether liver cirrhosis be present or not?
3. Please show the rationale for setting the cut-off value of AFP to 20and 400 ng/mL.
4. You mentioned “Tumor size, tumor number, HBsAg, capsule, arterial peripheral enhancement
and tumor margin were independent risk factors for predicting MVI. Tumor number, cirrhosis,
capsule and shape are independent risk factors for predicting high-grade HCC”. Which do you
think is better, MVI or HCC grade, to predict the prognosis or recurrence of patients with HCC?
I hope that my comments will be useful in improving the article.
Title: Clinical and imaging features Preoperative evaluation of histological grade and
microvascular infiltration of hepatocellular carcinoma
Version: 1 Date: 01 Jun 2022
Reviewer's report:
To the authors:
“Clinical and imaging features Preoperative evaluation of histological grade and microvascular
infiltration of hepatocellular carcinoma”
My comments are as follows.
1. Please unify the font in Table 3.
2. How did you judge whether liver cirrhosis be present or not?
3. Please show the rationale for setting the cut-off value of AFP to 20and 400 ng/mL.
4. You mentioned “Tumor size, tumor number, HBsAg, capsule, arterial peripheral enhancement
and tumor margin were independent risk factors for predicting MVI. Tumor number, cirrhosis,
capsule and shape are independent risk factors for predicting high-grade HCC”. Which do you
think is better, MVI or HCC grade, to predict the prognosis or recurrence of patients with HCC?
I hope that my comments will be useful in improving the article.
Please review this paper.
user
Title: Clinical and imaging features Preoperative evaluation of histological grade and
microvascular infiltration of hepatocellular carcinoma
Version: 1 Date: 01 Jun 2022
Reviewer's report:
To the authors:
“Clinical and imaging features Preoperative evaluation of histological grade and microvascular
infiltration of hepatocellular carcinoma”
My comments are as follows.
1. Please unify the font in Table 3.
2. How did you judge whether liver cirrhosis be present or not?
3. Please show the rationale for setting the cut-off value of AFP to 20and 400 ng/mL.
4. You mentioned “Tumor size, tumor number, HBsAg, capsule, arterial peripheral enhancement
and tumor margin were independent risk factors for predicting MVI. Tumor number, cirrhosis,
capsule and shape are independent risk factors for predicting high-grade HCC”. Which do you
think is better, MVI or HCC grade, to predict the prognosis or recurrence of patients with HCC?
I hope that my comments will be useful in improving the article.
assistant