Title: Magnetically Controlled Capsule Endoscopy in One-time Gastro-small Intestinal Joint
Examination: A Two-centre Experience
Version: 2 Date: 24 Feb 2022
Reviewer's report:
This retrospective study demonstrated the good efficacy of capsule endoscopy with active
locomotion system (MCE) to examine both the stomach and the small intestine in one session.
1.  In this study, GIB (melena) is the indication for MCE  in only 5.47% of the patients which is
much lower than the  GIB as an indication in other VCE studies.  Could you please  give more
details about the indications for MCE and how to extrapolate  to other groups of patients i.e.
patients with GIB  (for example, in patients with suspected small bowel bleeding that  sometimes
we need to repeat EGD before VCE).
2.  How do you  evaluate the visualization of small intestine mucosa? Do you use AI or use
samples of still pictures?
3. Do you have more information about the outcome of MCE (the change in management
compare to standard endoscopic examination in each indications)? For example, when MCE
were performed in patients with melena or GERD, is there any change in management when
compare with doing  only EGD?
Title: Magnetically Controlled Capsule Endoscopy in One-time Gastro-small Intestinal Joint
Examination: A Two-centre Experience
Version: 2 Date: 24 Feb 2022
Reviewer's report:
This retrospective study demonstrated the good efficacy of capsule endoscopy with active
locomotion system (MCE) to examine both the stomach and the small intestine in one session.
1.  In this study, GIB (melena) is the indication for MCE  in only 5.47% of the patients which is
much lower than the  GIB as an indication in other VCE studies.  Could you please  give more
details about the indications for MCE and how to extrapolate  to other groups of patients i.e.
patients with GIB  (for example, in patients with suspected small bowel bleeding that  sometimes
we need to repeat EGD before VCE).
2.  How do you  evaluate the visualization of small intestine mucosa? Do you use AI or use
samples of still pictures?
3. Do you have more information about the outcome of MCE (the change in management
compare to standard endoscopic examination in each indications)? For example, when MCE
were performed in patients with melena or GERD, is there any change in management when
compare with doing  only EGD?
Please review this paper.
user
Title: Magnetically Controlled Capsule Endoscopy in One-time Gastro-small Intestinal Joint
Examination: A Two-centre Experience
Version: 2 Date: 24 Feb 2022
Reviewer's report:
This retrospective study demonstrated the good efficacy of capsule endoscopy with active
locomotion system (MCE) to examine both the stomach and the small intestine in one session.
1.  In this study, GIB (melena) is the indication for MCE  in only 5.47% of the patients which is
much lower than the  GIB as an indication in other VCE studies.  Could you please  give more
details about the indications for MCE and how to extrapolate  to other groups of patients i.e.
patients with GIB  (for example, in patients with suspected small bowel bleeding that  sometimes
we need to repeat EGD before VCE).
2.  How do you  evaluate the visualization of small intestine mucosa? Do you use AI or use
samples of still pictures?
3. Do you have more information about the outcome of MCE (the change in management
compare to standard endoscopic examination in each indications)? For example, when MCE
were performed in patients with melena or GERD, is there any change in management when
compare with doing  only EGD?
assistant