Title: Temporal trends in disability adjusted life year and mortality for colorectal cancer
attributable to a high red meat diet in China from 1990 to 2021: an analysis of the Global Burden
of Disease Study 2021
Version: 1 Date: 13 Oct 2024
Reviewer:  Panagiotis Tsibouris
Reviewer's report:
Abbreviations should be explained on their first appearance in the text Authors should adopt
GBD data donot permit to evaluate increase in red meat consumption but only the percentage of
the country population consuming red meat Thus they should find a way to bridge the distance
Moreover they should compare  woman position in Chinease society and future projection
Morbidity and mortality projections should take into consideration future improvements in
health services Finally they should take into consideration that Ca bowel spends at least 10-15
years to develop from a small polyp to a full blown carcinoma Thus they can safely project
current status and get results in 15 years when current cicumstances will end up influencing
Ca bowel demographics Methods Authors should explain known factors in the equations they
provide ( hat a, b are stanging for) Distance between China's meat consumption and the mean of
industrialized countries, especially countries with similar cultural background should be taken
into consideration A projection to country's consumption 15 years ago might be closer to disease
pathophysiology  Mortality  and morbidity trends would be more obvious if compared with cases
not attributed in red meat and a ratio would be calculated
Title: Temporal trends in disability adjusted life year and mortality for colorectal cancer
attributable to a high red meat diet in China from 1990 to 2021: an analysis of the Global Burden
of Disease Study 2021
Version: 1 Date: 13 Oct 2024
Reviewer:  Panagiotis Tsibouris
Reviewer's report:
Abbreviations should be explained on their first appearance in the text Authors should adopt
GBD data donot permit to evaluate increase in red meat consumption but only the percentage of
the country population consuming red meat Thus they should find a way to bridge the distance
Moreover they should compare  woman position in Chinease society and future projection
Morbidity and mortality projections should take into consideration future improvements in
health services Finally they should take into consideration that Ca bowel spends at least 10-15
years to develop from a small polyp to a full blown carcinoma Thus they can safely project
current status and get results in 15 years when current cicumstances will end up influencing
Ca bowel demographics Methods Authors should explain known factors in the equations they
provide ( hat a, b are stanging for) Distance between China's meat consumption and the mean of
industrialized countries, especially countries with similar cultural background should be taken
into consideration A projection to country's consumption 15 years ago might be closer to disease
pathophysiology  Mortality  and morbidity trends would be more obvious if compared with cases
not attributed in red meat and a ratio would be calculated
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Title: Temporal trends in disability adjusted life year and mortality for colorectal cancer
attributable to a high red meat diet in China from 1990 to 2021: an analysis of the Global Burden
of Disease Study 2021
Version: 1 Date: 13 Oct 2024
Reviewer:  Panagiotis Tsibouris
Reviewer's report:
Abbreviations should be explained on their first appearance in the text Authors should adopt
GBD data donot permit to evaluate increase in red meat consumption but only the percentage of
the country population consuming red meat Thus they should find a way to bridge the distance
Moreover they should compare  woman position in Chinease society and future projection
Morbidity and mortality projections should take into consideration future improvements in
health services Finally they should take into consideration that Ca bowel spends at least 10-15
years to develop from a small polyp to a full blown carcinoma Thus they can safely project
current status and get results in 15 years when current cicumstances will end up influencing
Ca bowel demographics Methods Authors should explain known factors in the equations they
provide ( hat a, b are stanging for) Distance between China's meat consumption and the mean of
industrialized countries, especially countries with similar cultural background should be taken
into consideration A projection to country's consumption 15 years ago might be closer to disease
pathophysiology  Mortality  and morbidity trends would be more obvious if compared with cases
not attributed in red meat and a ratio would be calculated
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