Reviewer's report
Title:Long-term Follow up Helicobacter Pylori Reinfection Rate After
Second-Line Treatment: Bismuth-Containing Quadruple Therapy versus
Moxifloxacin-Based Triple Therapy
Version: 2Date:10 June 2013
Reviewer: Gian luigi de' Angelis
Reviewer's report:
Minor Essential Revisions
This study is well conducted and shows very interesting results, but:
- why patients were subjected to endoscopy after 1 year from diagnosis, if in
Korea the governement national health insurance program recommends biannual
endoscopy? If these patients needed endoscopy because of their clinical or
histological features, this have to be specified.
- in page 10, row 12: numbers used at the beginning of the sentences, should be
written in letter and not in digit (...show in table 3. 1 patient...).
- It would have been important to know among the reinfected patients, how many
subjects belonged at the same household: this data could give an idea about the
intrafamilial transmission rate, one of the most important transmission routes of
the H. pylori infection.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: Yes, but I do not feel adequately qualified to assess the
statistics.
Reviewer's report
Title:Long-term Follow up Helicobacter Pylori Reinfection Rate After
Second-Line Treatment: Bismuth-Containing Quadruple Therapy versus
Moxifloxacin-Based Triple Therapy
Version: 2Date:10 June 2013
Reviewer: Gian luigi de' Angelis
Reviewer's report:
Minor Essential Revisions
This study is well conducted and shows very interesting results, but:
- why patients were subjected to endoscopy after 1 year from diagnosis, if in
Korea the governement national health insurance program recommends biannual
endoscopy? If these patients needed endoscopy because of their clinical or
histological features, this have to be specified.
- in page 10, row 12: numbers used at the beginning of the sentences, should be
written in letter and not in digit (...show in table 3. 1 patient...).
- It would have been important to know among the reinfected patients, how many
subjects belonged at the same household: this data could give an idea about the
intrafamilial transmission rate, one of the most important transmission routes of
the H. pylori infection.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: Yes, but I do not feel adequately qualified to assess the
statistics.
Please review this paper.
user
Reviewer's report
Title:Long-term Follow up Helicobacter Pylori Reinfection Rate After
Second-Line Treatment: Bismuth-Containing Quadruple Therapy versus
Moxifloxacin-Based Triple Therapy
Version: 2Date:10 June 2013
Reviewer: Gian luigi de' Angelis
Reviewer's report:
Minor Essential Revisions
This study is well conducted and shows very interesting results, but:
- why patients were subjected to endoscopy after 1 year from diagnosis, if in
Korea the governement national health insurance program recommends biannual
endoscopy? If these patients needed endoscopy because of their clinical or
histological features, this have to be specified.
- in page 10, row 12: numbers used at the beginning of the sentences, should be
written in letter and not in digit (...show in table 3. 1 patient...).
- It would have been important to know among the reinfected patients, how many
subjects belonged at the same household: this data could give an idea about the
intrafamilial transmission rate, one of the most important transmission routes of
the H. pylori infection.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: Yes, but I do not feel adequately qualified to assess the
statistics.
assistant