Title: M64HCl, a focal adhesion kinase activator, promotes intestinal mucosal healing in rats
Version: 0 Date: 07 Aug 2024
Reviewer's report:
Manuscript is well written. Methods are sound and discussion highlights interesting and relevant
points for future investigations of M64HCl.
If possible, I would like to see in this manuscript the addition of ulcer scoring using the stated
pathological features in the histological analysis as well as quantifying the IHC of p-FAK.
It would be interesting to see, in the future, studies focusing on the mechanism of action of
M64HCl through the FAK-Src complex in this in vivo model, to support previous publications
in vitro.
Title: M64HCl, a focal adhesion kinase activator, promotes intestinal mucosal healing in rats
Version: 0 Date: 07 Aug 2024
Reviewer's report:
Manuscript is well written. Methods are sound and discussion highlights interesting and relevant
points for future investigations of M64HCl.
If possible, I would like to see in this manuscript the addition of ulcer scoring using the stated
pathological features in the histological analysis as well as quantifying the IHC of p-FAK.
It would be interesting to see, in the future, studies focusing on the mechanism of action of
M64HCl through the FAK-Src complex in this in vivo model, to support previous publications
in vitro.
Please review this paper.
user
Title: M64HCl, a focal adhesion kinase activator, promotes intestinal mucosal healing in rats
Version: 0 Date: 07 Aug 2024
Reviewer's report:
Manuscript is well written. Methods are sound and discussion highlights interesting and relevant
points for future investigations of M64HCl.
If possible, I would like to see in this manuscript the addition of ulcer scoring using the stated
pathological features in the histological analysis as well as quantifying the IHC of p-FAK.
It would be interesting to see, in the future, studies focusing on the mechanism of action of
M64HCl through the FAK-Src complex in this in vivo model, to support previous publications
in vitro.
assistant