Title: Effect of disease duration on fecal biomarkers in ulcerative colitis: A prospective cohort
study
Version: 0 Date: 05 May 2022
Reviewer:  Yuusaku Sugihara
Reviewer's report:
The authors evaluated the effect of UC disease duration on FC was investigated and compared
to that on FIT. The result is that Similar to FIT, FC is affected by the duration of UC, indicating
that FC may be a highly useful biomarker, especially in short-term disease.
 This report represents an effort to accomplish this, as these data will most likely prove to be
a unique resource well into the future. However, there are many similar papers#Evaluation of
mucosal healing of ulcerative colitis by a quantitative fecal immunochemical test, Nakarai et
al), and the author should devise a way to convey the problem to be solved more clearly to the
reader. In particular, it should be clearly stated in the introduction.
Title: Effect of disease duration on fecal biomarkers in ulcerative colitis: A prospective cohort
study
Version: 0 Date: 05 May 2022
Reviewer:  Yuusaku Sugihara
Reviewer's report:
The authors evaluated the effect of UC disease duration on FC was investigated and compared
to that on FIT. The result is that Similar to FIT, FC is affected by the duration of UC, indicating
that FC may be a highly useful biomarker, especially in short-term disease.
 This report represents an effort to accomplish this, as these data will most likely prove to be
a unique resource well into the future. However, there are many similar papers#Evaluation of
mucosal healing of ulcerative colitis by a quantitative fecal immunochemical test, Nakarai et
al), and the author should devise a way to convey the problem to be solved more clearly to the
reader. In particular, it should be clearly stated in the introduction.
Please review this paper.
user
Title: Effect of disease duration on fecal biomarkers in ulcerative colitis: A prospective cohort
study
Version: 0 Date: 05 May 2022
Reviewer:  Yuusaku Sugihara
Reviewer's report:
The authors evaluated the effect of UC disease duration on FC was investigated and compared
to that on FIT. The result is that Similar to FIT, FC is affected by the duration of UC, indicating
that FC may be a highly useful biomarker, especially in short-term disease.
 This report represents an effort to accomplish this, as these data will most likely prove to be
a unique resource well into the future. However, there are many similar papers#Evaluation of
mucosal healing of ulcerative colitis by a quantitative fecal immunochemical test, Nakarai et
al), and the author should devise a way to convey the problem to be solved more clearly to the
reader. In particular, it should be clearly stated in the introduction.
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