Title: Impact of second forward-view examination on adenoma detection rate during  unsedated
colonoscopy: a randomized controlled trial
Version: 2 Date: 08 Feb 2021
Reviewer's report:
1. the ADR of included colonoscopists should be illustrated
2. 2L-dose PEG might be inadequate for bowel preparation and I belive that the patients with
poor bowel preparation should be much more than 6 patients.
3. did the trial include patients with the indication of diagnosis?
4. the influence of only including unsedated patients should be discussed
5. how about the withdrawing techniques used in the trial and keeping them similar in for the
two arms?
6. did the withdrawing time include time for polypectomy?
7. "Endoscopic polypectomy or biopsy was performed when necessary." how does the author
define "necessary"?
8. sample size and outcomes should be separated from Statistical analysis, and more detail about
Statistical analysis should be addressed. 400 are needed for the trial while the final number of
included should be fewer than 400?
9. which one was the main outcome ADR or PDR? (used for sample size)
Title: Impact of second forward-view examination on adenoma detection rate during  unsedated
colonoscopy: a randomized controlled trial
Version: 2 Date: 08 Feb 2021
Reviewer's report:
1. the ADR of included colonoscopists should be illustrated
2. 2L-dose PEG might be inadequate for bowel preparation and I belive that the patients with
poor bowel preparation should be much more than 6 patients.
3. did the trial include patients with the indication of diagnosis?
4. the influence of only including unsedated patients should be discussed
5. how about the withdrawing techniques used in the trial and keeping them similar in for the
two arms?
6. did the withdrawing time include time for polypectomy?
7. "Endoscopic polypectomy or biopsy was performed when necessary." how does the author
define "necessary"?
8. sample size and outcomes should be separated from Statistical analysis, and more detail about
Statistical analysis should be addressed. 400 are needed for the trial while the final number of
included should be fewer than 400?
9. which one was the main outcome ADR or PDR? (used for sample size)
Please review this paper.
user
Title: Impact of second forward-view examination on adenoma detection rate during  unsedated
colonoscopy: a randomized controlled trial
Version: 2 Date: 08 Feb 2021
Reviewer's report:
1. the ADR of included colonoscopists should be illustrated
2. 2L-dose PEG might be inadequate for bowel preparation and I belive that the patients with
poor bowel preparation should be much more than 6 patients.
3. did the trial include patients with the indication of diagnosis?
4. the influence of only including unsedated patients should be discussed
5. how about the withdrawing techniques used in the trial and keeping them similar in for the
two arms?
6. did the withdrawing time include time for polypectomy?
7. "Endoscopic polypectomy or biopsy was performed when necessary." how does the author
define "necessary"?
8. sample size and outcomes should be separated from Statistical analysis, and more detail about
Statistical analysis should be addressed. 400 are needed for the trial while the final number of
included should be fewer than 400?
9. which one was the main outcome ADR or PDR? (used for sample size)
assistant