Title: Clinical characteristics and longitudinal changes of patients with non-alcoholic fatty liver
disease in two decades: the NAGALA study
Version: 2 Date: 02 Jan 2021
Reviewer's report:
- Introduction section: i suggest to report the data of global NAFLD pandemic, with regards
to the japanese status. I also suggest to report the metabolic, genetic and evironmental factors
linked with the onset and progression of NAFLD with references (i.e. 33349658; 27610012)
- Methods section: is important to report the tool used for the US diagnosis of liver steatosis. I
suggest to use, if is possible, the ultrasound parameters or scores like Hamaguchi socre
- Results section: the high number of non obese pts with NAFLD is related to the genetic profile
of the studied population
- Discussion section: is importnat to underline the fact that the global rise of NAFLD is related
to lifestile changes and in particular with high caloric diet
Title: Clinical characteristics and longitudinal changes of patients with non-alcoholic fatty liver
disease in two decades: the NAGALA study
Version: 2 Date: 02 Jan 2021
Reviewer's report:
- Introduction section: i suggest to report the data of global NAFLD pandemic, with regards
to the japanese status. I also suggest to report the metabolic, genetic and evironmental factors
linked with the onset and progression of NAFLD with references (i.e. 33349658; 27610012)
- Methods section: is important to report the tool used for the US diagnosis of liver steatosis. I
suggest to use, if is possible, the ultrasound parameters or scores like Hamaguchi socre
- Results section: the high number of non obese pts with NAFLD is related to the genetic profile
of the studied population
- Discussion section: is importnat to underline the fact that the global rise of NAFLD is related
to lifestile changes and in particular with high caloric diet
Please review this paper.
user
Title: Clinical characteristics and longitudinal changes of patients with non-alcoholic fatty liver
disease in two decades: the NAGALA study
Version: 2 Date: 02 Jan 2021
Reviewer's report:
- Introduction section: i suggest to report the data of global NAFLD pandemic, with regards
to the japanese status. I also suggest to report the metabolic, genetic and evironmental factors
linked with the onset and progression of NAFLD with references (i.e. 33349658; 27610012)
- Methods section: is important to report the tool used for the US diagnosis of liver steatosis. I
suggest to use, if is possible, the ultrasound parameters or scores like Hamaguchi socre
- Results section: the high number of non obese pts with NAFLD is related to the genetic profile
of the studied population
- Discussion section: is importnat to underline the fact that the global rise of NAFLD is related
to lifestile changes and in particular with high caloric diet
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