Title: Regression in hepatic fibrosis in elderly Chinese patients with hepatitis C receiving direct-
acting antiviral treatment
Version: 0 Date: 08 Dec 2022
Reviewer's report:
Authors demonstrated age, LSM, and CAP were identified as independent predictors of fibrosis
regression in elderly patients with CHC.
This phenomenon is interesting, as our field asks how little is known about the benefits of
successful anti-viral treatment to older patients with hepatic fibrosis.
Authors report that the degree of hepatic steatosis expressed by the CAP value did not
significantly change as a result of treatment for the elderly group. Nutritional status and the
presence of sarcopenia should also be considered as influencing factors.
Alcoholic disease is an exclusion criterion, but the duration and amount of alcohol consumption
should be considered as an influence on fibrosis progression.
Title: Regression in hepatic fibrosis in elderly Chinese patients with hepatitis C receiving direct-
acting antiviral treatment
Version: 0 Date: 08 Dec 2022
Reviewer's report:
Authors demonstrated age, LSM, and CAP were identified as independent predictors of fibrosis
regression in elderly patients with CHC.
This phenomenon is interesting, as our field asks how little is known about the benefits of
successful anti-viral treatment to older patients with hepatic fibrosis.
Authors report that the degree of hepatic steatosis expressed by the CAP value did not
significantly change as a result of treatment for the elderly group. Nutritional status and the
presence of sarcopenia should also be considered as influencing factors.
Alcoholic disease is an exclusion criterion, but the duration and amount of alcohol consumption
should be considered as an influence on fibrosis progression.
Please review this paper.
user
Title: Regression in hepatic fibrosis in elderly Chinese patients with hepatitis C receiving direct-
acting antiviral treatment
Version: 0 Date: 08 Dec 2022
Reviewer's report:
Authors demonstrated age, LSM, and CAP were identified as independent predictors of fibrosis
regression in elderly patients with CHC.
This phenomenon is interesting, as our field asks how little is known about the benefits of
successful anti-viral treatment to older patients with hepatic fibrosis.
Authors report that the degree of hepatic steatosis expressed by the CAP value did not
significantly change as a result of treatment for the elderly group. Nutritional status and the
presence of sarcopenia should also be considered as influencing factors.
Alcoholic disease is an exclusion criterion, but the duration and amount of alcohol consumption
should be considered as an influence on fibrosis progression.
assistant