Title: Additive effect of evaluating microsurface and microvascular patterns using magnifying
endoscopy with narrow-band imaging in gastric cancer: a post hoc analysis of a single- center
observational study
Version: 2 Date: 17 Feb 2022
Reviewer's report:
Thank you for your reply. I still have some concerns.
Major
1. Cohen's kappa is used to compare two raters, but Fleiss' kappa is suitable for more of them.
Therefore, to keep high level of statistical analysis of the manuscript it should be calculated
accordingly.
Another example: Roma#czyk M et al. Scoring system assessing mucosal visibility of upper
gastrointestinal tract: The POLPREP scale. J Gastroenterol Hepatol.
Minor:
1. As I have mentioned previously no definition of Accuracy is needed (lines 147-149). Accuracy
is always true positives+true negatives/all of cases.
2. Mehtods section “When multiple classifications exhibited the maximum number of answers,
the final diagnosis was regarded as “inconclusive.”” What was the threshold value?
3. As another analysis of MS alone was done, methods section should be updated accordingly.
For example, in the sentence “In this study, we aimed to evaluate the respective contributions
of MS and MV patterns for diagnosing patients with gastric cancer and to assess the differences
in diagnostic performance between the combination of MS and MV and MV alone.” MS alone
should be added.
Title: Additive effect of evaluating microsurface and microvascular patterns using magnifying
endoscopy with narrow-band imaging in gastric cancer: a post hoc analysis of a single- center
observational study
Version: 2 Date: 17 Feb 2022
Reviewer's report:
Thank you for your reply. I still have some concerns.
Major
1. Cohen's kappa is used to compare two raters, but Fleiss' kappa is suitable for more of them.
Therefore, to keep high level of statistical analysis of the manuscript it should be calculated
accordingly.
Another example: Roma#czyk M et al. Scoring system assessing mucosal visibility of upper
gastrointestinal tract: The POLPREP scale. J Gastroenterol Hepatol.
Minor:
1. As I have mentioned previously no definition of Accuracy is needed (lines 147-149). Accuracy
is always true positives+true negatives/all of cases.
2. Mehtods section “When multiple classifications exhibited the maximum number of answers,
the final diagnosis was regarded as “inconclusive.”” What was the threshold value?
3. As another analysis of MS alone was done, methods section should be updated accordingly.
For example, in the sentence “In this study, we aimed to evaluate the respective contributions
of MS and MV patterns for diagnosing patients with gastric cancer and to assess the differences
in diagnostic performance between the combination of MS and MV and MV alone.” MS alone
should be added.
Please review this paper.
user
Title: Additive effect of evaluating microsurface and microvascular patterns using magnifying
endoscopy with narrow-band imaging in gastric cancer: a post hoc analysis of a single- center
observational study
Version: 2 Date: 17 Feb 2022
Reviewer's report:
Thank you for your reply. I still have some concerns.
Major
1. Cohen's kappa is used to compare two raters, but Fleiss' kappa is suitable for more of them.
Therefore, to keep high level of statistical analysis of the manuscript it should be calculated
accordingly.
Another example: Roma#czyk M et al. Scoring system assessing mucosal visibility of upper
gastrointestinal tract: The POLPREP scale. J Gastroenterol Hepatol.
Minor:
1. As I have mentioned previously no definition of Accuracy is needed (lines 147-149). Accuracy
is always true positives+true negatives/all of cases.
2. Mehtods section “When multiple classifications exhibited the maximum number of answers,
the final diagnosis was regarded as “inconclusive.”” What was the threshold value?
3. As another analysis of MS alone was done, methods section should be updated accordingly.
For example, in the sentence “In this study, we aimed to evaluate the respective contributions
of MS and MV patterns for diagnosing patients with gastric cancer and to assess the differences
in diagnostic performance between the combination of MS and MV and MV alone.” MS alone
should be added.
assistant