Reviewer's report
Title:High-definition endoscopy with digital chromoendoscopy for histologic
prediction of distal colorectal polyps
Version:2Date:17 July 2015
Reviewer: Marietta Iacucci
Reviewer's report:
Minor Essential Revisions
Rath et al have performed a study to assess if high definition iscan digital
chromoendoscopy can accurately predict the histology of distal diminutive
colorectal polyps according to the ASGE PIVI statement.
They have shown that digital chromoendoscopy with iscan can reliably predict
histology of distal diminutive polyps in real time according to the
recommendations of the ASGE PIVI statement
Despite the fact that the study has been performed by only one expert
endoscopist , which represents a limitation ,the manuscript is interesting and
endoscopically relevant .
It would be important to have the intra-observer agreement of the single operator.
Please provide more pictures of digital chromoendoscopy of the diminutive
polyps analyzed . It would be important to show to the readers which are the
endoscopic findings that differentiate between diminutive adenoma and
hyperplastic polyp using High Definition iscan digital chromoendoscopy.
It will also be important to highlight what is visible at iSCAN chromoendoscopy
that is not visible by white light High Definition endoscopy that enables precise
histology level classification.
.
It would be relevant in the future doing the same study with multiple experts and
endoscopists and not just expert endoscopists to assess the inter-observer
agreement and accuracy to predictive histology , interval of surveillance
colonoscopy and learning curve of diminutive distal colonic polyps using digital
chromoendoscopic modalities. It is important demonstrate in the future that digital
chromoendoscopy is as precise as as optical chromoendoscopy and dye
spraying.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
No
Reviewer's report
Title:High-definition endoscopy with digital chromoendoscopy for histologic
prediction of distal colorectal polyps
Version:2Date:17 July 2015
Reviewer: Marietta Iacucci
Reviewer's report:
Minor Essential Revisions
Rath et al have performed a study to assess if high definition iscan digital
chromoendoscopy can accurately predict the histology of distal diminutive
colorectal polyps according to the ASGE PIVI statement.
They have shown that digital chromoendoscopy with iscan can reliably predict
histology of distal diminutive polyps in real time according to the
recommendations of the ASGE PIVI statement
Despite the fact that the study has been performed by only one expert
endoscopist , which represents a limitation ,the manuscript is interesting and
endoscopically relevant .
It would be important to have the intra-observer agreement of the single operator.
Please provide more pictures of digital chromoendoscopy of the diminutive
polyps analyzed . It would be important to show to the readers which are the
endoscopic findings that differentiate between diminutive adenoma and
hyperplastic polyp using High Definition iscan digital chromoendoscopy.
It will also be important to highlight what is visible at iSCAN chromoendoscopy
that is not visible by white light High Definition endoscopy that enables precise
histology level classification.
.
It would be relevant in the future doing the same study with multiple experts and
endoscopists and not just expert endoscopists to assess the inter-observer
agreement and accuracy to predictive histology , interval of surveillance
colonoscopy and learning curve of diminutive distal colonic polyps using digital
chromoendoscopic modalities. It is important demonstrate in the future that digital
chromoendoscopy is as precise as as optical chromoendoscopy and dye
spraying.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
No
Please review this paper.
user
Reviewer's report
Title:High-definition endoscopy with digital chromoendoscopy for histologic
prediction of distal colorectal polyps
Version:2Date:17 July 2015
Reviewer: Marietta Iacucci
Reviewer's report:
Minor Essential Revisions
Rath et al have performed a study to assess if high definition iscan digital
chromoendoscopy can accurately predict the histology of distal diminutive
colorectal polyps according to the ASGE PIVI statement.
They have shown that digital chromoendoscopy with iscan can reliably predict
histology of distal diminutive polyps in real time according to the
recommendations of the ASGE PIVI statement
Despite the fact that the study has been performed by only one expert
endoscopist , which represents a limitation ,the manuscript is interesting and
endoscopically relevant .
It would be important to have the intra-observer agreement of the single operator.
Please provide more pictures of digital chromoendoscopy of the diminutive
polyps analyzed . It would be important to show to the readers which are the
endoscopic findings that differentiate between diminutive adenoma and
hyperplastic polyp using High Definition iscan digital chromoendoscopy.
It will also be important to highlight what is visible at iSCAN chromoendoscopy
that is not visible by white light High Definition endoscopy that enables precise
histology level classification.
.
It would be relevant in the future doing the same study with multiple experts and
endoscopists and not just expert endoscopists to assess the inter-observer
agreement and accuracy to predictive histology , interval of surveillance
colonoscopy and learning curve of diminutive distal colonic polyps using digital
chromoendoscopic modalities. It is important demonstrate in the future that digital
chromoendoscopy is as precise as as optical chromoendoscopy and dye
spraying.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
No
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