Title: Advantages Comparison of Peritoneal Drainage versus No Drainage after Laparoscopic
Appendectomy for Complicated Appendicitis: A Meta-analysis
Version: 3 Date: 08 Sep 2024
Reviewer:  Ali Yasen Y. Mohamedahmed
Reviewer's report:
Thank you for the opportunity to review this systematic review and meta-analysis. It's well
conducted with a reasonable methodology and statistics. However, I have one major concern
which is combining complicated and complicated appendicitis in the analysis. Usually, a
peritoneal drain is used when there is perforated appendicitis or an appendicular mass. I believe
authors need to address this either by excluding simple, uncomplicated appendicitis or by
creating a subgroup analysis for studies that only included complicated appendicitis.
Also, in the discussion, the authors mentioned: ( Currently, there are limited meta-analyses
assessing the utility of PD following laparoscopic appendectomy.) There are at least two other
meta-analyses on this topic (https://doi.org/10.3389/fsurg.2022.1086877) and (DOI: 10.7759/
cureus.32018 ); please explain what this study is adding to the literature if the view of already
available meta-analysis.
Title: Advantages Comparison of Peritoneal Drainage versus No Drainage after Laparoscopic
Appendectomy for Complicated Appendicitis: A Meta-analysis
Version: 3 Date: 08 Sep 2024
Reviewer:  Ali Yasen Y. Mohamedahmed
Reviewer's report:
Thank you for the opportunity to review this systematic review and meta-analysis. It's well
conducted with a reasonable methodology and statistics. However, I have one major concern
which is combining complicated and complicated appendicitis in the analysis. Usually, a
peritoneal drain is used when there is perforated appendicitis or an appendicular mass. I believe
authors need to address this either by excluding simple, uncomplicated appendicitis or by
creating a subgroup analysis for studies that only included complicated appendicitis.
Also, in the discussion, the authors mentioned: ( Currently, there are limited meta-analyses
assessing the utility of PD following laparoscopic appendectomy.) There are at least two other
meta-analyses on this topic (https://doi.org/10.3389/fsurg.2022.1086877) and (DOI: 10.7759/
cureus.32018 ); please explain what this study is adding to the literature if the view of already
available meta-analysis.
Please review this paper.
user
Title: Advantages Comparison of Peritoneal Drainage versus No Drainage after Laparoscopic
Appendectomy for Complicated Appendicitis: A Meta-analysis
Version: 3 Date: 08 Sep 2024
Reviewer:  Ali Yasen Y. Mohamedahmed
Reviewer's report:
Thank you for the opportunity to review this systematic review and meta-analysis. It's well
conducted with a reasonable methodology and statistics. However, I have one major concern
which is combining complicated and complicated appendicitis in the analysis. Usually, a
peritoneal drain is used when there is perforated appendicitis or an appendicular mass. I believe
authors need to address this either by excluding simple, uncomplicated appendicitis or by
creating a subgroup analysis for studies that only included complicated appendicitis.
Also, in the discussion, the authors mentioned: ( Currently, there are limited meta-analyses
assessing the utility of PD following laparoscopic appendectomy.) There are at least two other
meta-analyses on this topic (https://doi.org/10.3389/fsurg.2022.1086877) and (DOI: 10.7759/
cureus.32018 ); please explain what this study is adding to the literature if the view of already
available meta-analysis.
assistant