Reviewer's report
Title:Predictors Of Gastrointestinal Lesions On Endoscopy In Iron Deficiency
Anemia Without Gastrointestinal Symptoms
Version: 2Date:5 May 2008
Reviewer: Alistair W Stewart
Reviewer's report:
Major Compulsory Revisions
In table 5 the %’s of Hx of weight loss are wrong. I pointed this out in my previous
review of this paper and it has not changed.
In Tables 3 and 5 there is confusion with the odds ratios and, possibly, with some
percentages. It is important that the odds ratios are attributed to a group with the
other group as the reference. The table heading, or a footnote, must specify
which group is being used as the reference group. The appearance is that, in
Table 3, that the ‘No endoscopic lesions identified’ group is the reference group.
The OR for age ge 55 however uses the other group as the reference group. In
table 5 it appears that the wrong reference group has been used in the serum
iron and ferritin calculations of the OR.
Again in Tables 3 and 5 there is the unusual situation where a measure has a
greater mean in one group compared to the other and yet the proportion less
than a fixed value is also greater. This occurs in Table 3 ferritin and Table 5
serum iron and ferritin. It is possible for this situation to occur but it is unlikely.
Could the authors please check this carefully.
Why has a 10 µg/dl been used in table 3 and a cut off of 5 µg/dl been used in
Table 5 for serum iron and the reverse been used for ferritin? This has changed
since the previous submission.
Minor Essential Revisions
In the text it stated that MCV #60fl (OR 514.8, 95% CI 3.6 – 60.7) which is clearly
a typographical error.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: Yes, and I have assessed the statistics in my report.
Declaration of competing interests:
'I declare that I have no competing interests'
Reviewer's report
Title:Predictors Of Gastrointestinal Lesions On Endoscopy In Iron Deficiency
Anemia Without Gastrointestinal Symptoms
Version: 2Date:5 May 2008
Reviewer: Alistair W Stewart
Reviewer's report:
Major Compulsory Revisions
In table 5 the %’s of Hx of weight loss are wrong. I pointed this out in my previous
review of this paper and it has not changed.
In Tables 3 and 5 there is confusion with the odds ratios and, possibly, with some
percentages. It is important that the odds ratios are attributed to a group with the
other group as the reference. The table heading, or a footnote, must specify
which group is being used as the reference group. The appearance is that, in
Table 3, that the ‘No endoscopic lesions identified’ group is the reference group.
The OR for age ge 55 however uses the other group as the reference group. In
table 5 it appears that the wrong reference group has been used in the serum
iron and ferritin calculations of the OR.
Again in Tables 3 and 5 there is the unusual situation where a measure has a
greater mean in one group compared to the other and yet the proportion less
than a fixed value is also greater. This occurs in Table 3 ferritin and Table 5
serum iron and ferritin. It is possible for this situation to occur but it is unlikely.
Could the authors please check this carefully.
Why has a 10 µg/dl been used in table 3 and a cut off of 5 µg/dl been used in
Table 5 for serum iron and the reverse been used for ferritin? This has changed
since the previous submission.
Minor Essential Revisions
In the text it stated that MCV #60fl (OR 514.8, 95% CI 3.6 – 60.7) which is clearly
a typographical error.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: Yes, and I have assessed the statistics in my report.
Declaration of competing interests:
'I declare that I have no competing interests'
Please review this paper.
user
Reviewer's report
Title:Predictors Of Gastrointestinal Lesions On Endoscopy In Iron Deficiency
Anemia Without Gastrointestinal Symptoms
Version: 2Date:5 May 2008
Reviewer: Alistair W Stewart
Reviewer's report:
Major Compulsory Revisions
In table 5 the %’s of Hx of weight loss are wrong. I pointed this out in my previous
review of this paper and it has not changed.
In Tables 3 and 5 there is confusion with the odds ratios and, possibly, with some
percentages. It is important that the odds ratios are attributed to a group with the
other group as the reference. The table heading, or a footnote, must specify
which group is being used as the reference group. The appearance is that, in
Table 3, that the ‘No endoscopic lesions identified’ group is the reference group.
The OR for age ge 55 however uses the other group as the reference group. In
table 5 it appears that the wrong reference group has been used in the serum
iron and ferritin calculations of the OR.
Again in Tables 3 and 5 there is the unusual situation where a measure has a
greater mean in one group compared to the other and yet the proportion less
than a fixed value is also greater. This occurs in Table 3 ferritin and Table 5
serum iron and ferritin. It is possible for this situation to occur but it is unlikely.
Could the authors please check this carefully.
Why has a 10 µg/dl been used in table 3 and a cut off of 5 µg/dl been used in
Table 5 for serum iron and the reverse been used for ferritin? This has changed
since the previous submission.
Minor Essential Revisions
In the text it stated that MCV #60fl (OR 514.8, 95% CI 3.6 – 60.7) which is clearly
a typographical error.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: Yes, and I have assessed the statistics in my report.
Declaration of competing interests:
'I declare that I have no competing interests'
assistant