Reviewer ’s report  
 
Title: Case report of Hepatic artery dissection secondary to hepatic artery pseudoaneurysm after 
living donor liver transplantation  
 
 
Version: 0 Date: 10 Oct 2015  
 
 
Reviewer: King -Wah Chiu   
 
 
Reviewer's report:  
 
1. This is a case report with fatal later  complication regarding to hepatic arterial pseudo -
aneurysm and hepatic arterial dissection after LDLT.   
 
2. The manuscript warrants important English language revision; grammar errors not only 
make reading difficult, but threaten to distort meaning.  
 
3. The manuscript is not flowing, is disjointed, and does not correspond to the established 
order of a scientific article such as  
 
A. "A 43 -year-old man with severe acute hepatitis B infection underwent right -lobe LDLT" 
may be change to "A 43 -year-old male pat ient suffered from severe acute hepatitis B 
infection and liver failure underwent LDLT with right lobe graft".  
 
B. "Ultrasound revealed mild right pleural and peritoneal effusion" it may let the readers to 
have a confusion that what about the difference bet ween the peritoneal effusion and 
ascites.  
 
4. It is not clear if medical protocols are based on "humanitarian" reasons or also on medical 
reasons, and the problem is not indifferent especially in the setting of liver 
transplantation. The initial bleeder hav e not been identified in this case report. The 
approach of the initial detection of hepatic arterial pseudo -aneurysm might be more 
questionable. Early surgical repairmen should be consider immediately when the hepatic 
arterial dissection detected by the ul trasonography. The outcome is let the readers' 
disappointment leading to the CEUS scientifically unsound.  
 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
No 
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
Unable to assess  
 
Are the conclusions drawn adequat ely supported by the data shown?  
If not, please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in the manuscript or would you recommend an  
additional statistical review?  
If an additional statistical review is recommended , please specify what aspects require further  
assessment in your comments to the editors.  
 
Not relevant to this manuscript  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Not suitable for publication unless extensively edited  
 
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following questions:  
 
1. Have you in the past five years received reimbursements, fees, funding, or salary from 
an organisation that may in any way gain or lose financially from the publication of this  
manuscript, either now or in the future?  
 
2. Do you hold any stocks or shares i n an organisation that may in any way gain or lose  
financially from the publication of this manuscript, either now or in the future?  
 
3. Do you hold or are you currently applying for any patents relating to the content of the  
manuscript?  
 
4. Have you receive d reimbursements, fees, funding, or salary from an organization that 
holds  or has applied for patents relating to the content of the manuscript?  
 
5. Do you have any other financial competing interests?  
 
6. Do you have any non -financial competing interests in  relation to this paper?  
 
If you can answer no to all of the above, write 'I declare that I have no competing interests' 
below.  If your reply is yes to any, please give details below.  
 
I have not any competing interests here.  
 
I agree to the open peer review policy of the journ al. I understand that my name will be included  
on my report to the authors and, if the manuscript is accepted for publication, my named report  
including any attachments I upload will be posted on the website along with the authors'  
responses. I agree for my report to be made available under an Open Access Creative Commons  
CC-BY license ( http://creativecommons.org/licenses/by/4.0/ ). I understand that any comments  
which I do not wish to be included in my named report can be included as  confidential comments  
to the editors, which will not be published.  
 
I agree to the open peer review policy of the journal  
Reviewer ’s report  
 
Title: Case report of Hepatic artery dissection secondary to hepatic artery pseudoaneurysm after 
living donor liver transplantation  
 
 
Version: 0 Date: 10 Oct 2015  
 
 
Reviewer: King -Wah Chiu   
 
 
Reviewer's report:  
 
1. This is a case report with fatal later  complication regarding to hepatic arterial pseudo -
aneurysm and hepatic arterial dissection after LDLT.   
 
2. The manuscript warrants important English language revision; grammar errors not only 
make reading difficult, but threaten to distort meaning.  
 
3. The manuscript is not flowing, is disjointed, and does not correspond to the established 
order of a scientific article such as  
 
A. "A 43 -year-old man with severe acute hepatitis B infection underwent right -lobe LDLT" 
may be change to "A 43 -year-old male pat ient suffered from severe acute hepatitis B 
infection and liver failure underwent LDLT with right lobe graft".  
 
B. "Ultrasound revealed mild right pleural and peritoneal effusion" it may let the readers to 
have a confusion that what about the difference bet ween the peritoneal effusion and 
ascites.  
 
4. It is not clear if medical protocols are based on "humanitarian" reasons or also on medical 
reasons, and the problem is not indifferent especially in the setting of liver 
transplantation. The initial bleeder hav e not been identified in this case report. The 
approach of the initial detection of hepatic arterial pseudo -aneurysm might be more 
questionable. Early surgical repairmen should be consider immediately when the hepatic 
arterial dissection detected by the ul trasonography. The outcome is let the readers' 
disappointment leading to the CEUS scientifically unsound.  
 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
No 
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
Unable to assess  
 
Are the conclusions drawn adequat ely supported by the data shown?  
If not, please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in the manuscript or would you recommend an  
additional statistical review?  
If an additional statistical review is recommended , please specify what aspects require further  
assessment in your comments to the editors.  
 
Not relevant to this manuscript  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Not suitable for publication unless extensively edited  
 
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following questions:  
 
1. Have you in the past five years received reimbursements, fees, funding, or salary from 
an organisation that may in any way gain or lose financially from the publication of this  
manuscript, either now or in the future?  
 
2. Do you hold any stocks or shares i n an organisation that may in any way gain or lose  
financially from the publication of this manuscript, either now or in the future?  
 
3. Do you hold or are you currently applying for any patents relating to the content of the  
manuscript?  
 
4. Have you receive d reimbursements, fees, funding, or salary from an organization that 
holds  or has applied for patents relating to the content of the manuscript?  
 
5. Do you have any other financial competing interests?  
 
6. Do you have any non -financial competing interests in  relation to this paper?  
 
If you can answer no to all of the above, write 'I declare that I have no competing interests' 
below.  If your reply is yes to any, please give details below.  
 
I have not any competing interests here.  
 
I agree to the open peer review policy of the journ al. I understand that my name will be included  
on my report to the authors and, if the manuscript is accepted for publication, my named report  
including any attachments I upload will be posted on the website along with the authors'  
responses. I agree for my report to be made available under an Open Access Creative Commons  
CC-BY license ( http://creativecommons.org/licenses/by/4.0/ ). I understand that any comments  
which I do not wish to be included in my named report can be included as  confidential comments  
to the editors, which will not be published.  
 
I agree to the open peer review policy of the journal  
Please review this paper.
user
Reviewer ’s report  
 
Title: Case report of Hepatic artery dissection secondary to hepatic artery pseudoaneurysm after 
living donor liver transplantation  
 
 
Version: 0 Date: 10 Oct 2015  
 
 
Reviewer: King -Wah Chiu   
 
 
Reviewer's report:  
 
1. This is a case report with fatal later  complication regarding to hepatic arterial pseudo -
aneurysm and hepatic arterial dissection after LDLT.   
 
2. The manuscript warrants important English language revision; grammar errors not only 
make reading difficult, but threaten to distort meaning.  
 
3. The manuscript is not flowing, is disjointed, and does not correspond to the established 
order of a scientific article such as  
 
A. "A 43 -year-old man with severe acute hepatitis B infection underwent right -lobe LDLT" 
may be change to "A 43 -year-old male pat ient suffered from severe acute hepatitis B 
infection and liver failure underwent LDLT with right lobe graft".  
 
B. "Ultrasound revealed mild right pleural and peritoneal effusion" it may let the readers to 
have a confusion that what about the difference bet ween the peritoneal effusion and 
ascites.  
 
4. It is not clear if medical protocols are based on "humanitarian" reasons or also on medical 
reasons, and the problem is not indifferent especially in the setting of liver 
transplantation. The initial bleeder hav e not been identified in this case report. The 
approach of the initial detection of hepatic arterial pseudo -aneurysm might be more 
questionable. Early surgical repairmen should be consider immediately when the hepatic 
arterial dissection detected by the ul trasonography. The outcome is let the readers' 
disappointment leading to the CEUS scientifically unsound.  
 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
No 
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
Unable to assess  
 
Are the conclusions drawn adequat ely supported by the data shown?  
If not, please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in the manuscript or would you recommend an  
additional statistical review?  
If an additional statistical review is recommended , please specify what aspects require further  
assessment in your comments to the editors.  
 
Not relevant to this manuscript  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Not suitable for publication unless extensively edited  
 
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following questions:  
 
1. Have you in the past five years received reimbursements, fees, funding, or salary from 
an organisation that may in any way gain or lose financially from the publication of this  
manuscript, either now or in the future?  
 
2. Do you hold any stocks or shares i n an organisation that may in any way gain or lose  
financially from the publication of this manuscript, either now or in the future?  
 
3. Do you hold or are you currently applying for any patents relating to the content of the  
manuscript?  
 
4. Have you receive d reimbursements, fees, funding, or salary from an organization that 
holds  or has applied for patents relating to the content of the manuscript?  
 
5. Do you have any other financial competing interests?  
 
6. Do you have any non -financial competing interests in  relation to this paper?  
 
If you can answer no to all of the above, write 'I declare that I have no competing interests' 
below.  If your reply is yes to any, please give details below.  
 
I have not any competing interests here.  
 
I agree to the open peer review policy of the journ al. I understand that my name will be included  
on my report to the authors and, if the manuscript is accepted for publication, my named report  
including any attachments I upload will be posted on the website along with the authors'  
responses. I agree for my report to be made available under an Open Access Creative Commons  
CC-BY license ( http://creativecommons.org/licenses/by/4.0/ ). I understand that any comments  
which I do not wish to be included in my named report can be included as  confidential comments  
to the editors, which will not be published.  
 
I agree to the open peer review policy of the journal  
assistant