Title: Title # Clinical-pathological characteristics and prognostic factors for malignant
peritoneal mesothelioma in the elderly
Version: 0 Date: 15 Nov 2021
Reviewer's report:
The  authors  reported the clinicopathological characteristics and prognostic factors for
malignant peritoneal mesothelioma in the elderly from SEER data.
This is an interesting topic and few papers have been published in the international literature
and there si a need for such paper to be published
But the study has limitations and wording to be corrected before  to be accepted for publication.
The major limitations  and revisions that should be taken into account are:
1° in methods the histological classification should be mentionned (which type of
classification?)
What is the exact meaning of unknown how it has been defined.
2° The stage should be defined accordingly to international guideline
3° What is the meaning of differentiated grade. The authors should clarify how they have
evaluated the grade on which criteria?  wich criteria they have used and based their analysis
( paper? WHO classification?)
4° how they defined cancer curative surgery ( extensive or localized or others?)
5° which type of  radiation? combined ? not combined?
6° which type of chemotherapy
6° Could the authors defined the associated  comorbidities?
7° Could the authors clarify the change   of practice and treatment management  during the
period of time analyzed? 1975-2016
The figures could be modified with new histopathological criteria or discussed for a better
understanding and appreciation of the survival curves
Minimal revision
Line 48 epithelioid tissues is not appropriate it is from mesothelial origin
Line  49 SV40 is not considered as a reliable epidemiological factor it is not up to date now
Line 110 patients instead of patents
Title: Title # Clinical-pathological characteristics and prognostic factors for malignant
peritoneal mesothelioma in the elderly
Version: 0 Date: 15 Nov 2021
Reviewer's report:
The  authors  reported the clinicopathological characteristics and prognostic factors for
malignant peritoneal mesothelioma in the elderly from SEER data.
This is an interesting topic and few papers have been published in the international literature
and there si a need for such paper to be published
But the study has limitations and wording to be corrected before  to be accepted for publication.
The major limitations  and revisions that should be taken into account are:
1° in methods the histological classification should be mentionned (which type of
classification?)
What is the exact meaning of unknown how it has been defined.
2° The stage should be defined accordingly to international guideline
3° What is the meaning of differentiated grade. The authors should clarify how they have
evaluated the grade on which criteria?  wich criteria they have used and based their analysis
( paper? WHO classification?)
4° how they defined cancer curative surgery ( extensive or localized or others?)
5° which type of  radiation? combined ? not combined?
6° which type of chemotherapy
6° Could the authors defined the associated  comorbidities?
7° Could the authors clarify the change   of practice and treatment management  during the
period of time analyzed? 1975-2016
The figures could be modified with new histopathological criteria or discussed for a better
understanding and appreciation of the survival curves
Minimal revision
Line 48 epithelioid tissues is not appropriate it is from mesothelial origin
Line  49 SV40 is not considered as a reliable epidemiological factor it is not up to date now
Line 110 patients instead of patents
Please review this paper.
user
Title: Title # Clinical-pathological characteristics and prognostic factors for malignant
peritoneal mesothelioma in the elderly
Version: 0 Date: 15 Nov 2021
Reviewer's report:
The  authors  reported the clinicopathological characteristics and prognostic factors for
malignant peritoneal mesothelioma in the elderly from SEER data.
This is an interesting topic and few papers have been published in the international literature
and there si a need for such paper to be published
But the study has limitations and wording to be corrected before  to be accepted for publication.
The major limitations  and revisions that should be taken into account are:
1° in methods the histological classification should be mentionned (which type of
classification?)
What is the exact meaning of unknown how it has been defined.
2° The stage should be defined accordingly to international guideline
3° What is the meaning of differentiated grade. The authors should clarify how they have
evaluated the grade on which criteria?  wich criteria they have used and based their analysis
( paper? WHO classification?)
4° how they defined cancer curative surgery ( extensive or localized or others?)
5° which type of  radiation? combined ? not combined?
6° which type of chemotherapy
6° Could the authors defined the associated  comorbidities?
7° Could the authors clarify the change   of practice and treatment management  during the
period of time analyzed? 1975-2016
The figures could be modified with new histopathological criteria or discussed for a better
understanding and appreciation of the survival curves
Minimal revision
Line 48 epithelioid tissues is not appropriate it is from mesothelial origin
Line  49 SV40 is not considered as a reliable epidemiological factor it is not up to date now
Line 110 patients instead of patents
assistant