Reviewer's report
Title:Adenocarcinoma developed from remnant cystic duct after cholecystectomy
Version:3Date:22 July 2014
Reviewer: Andrea Cariati
Reviewer's report:
To authors: to improve the discussion chapter reporting these debate:
The long cystic duct stump is a site where gallstones can form "de novo" in
fact authors demonstrated gallstones before the onset of the adenocarcinoma
and
it could be useful to report in the references the abstract of Cetta F et al..
Cariati A etc here enclosed in the email
A-518 AGA ABSTRACTS
G2110
ROLE OF BILE ACID PROPHYLAXIS IN THE PREVENTION OF
RECURRENT CHOLESTEROL STONES FORMING IN THE CYSTIC
REMNANT AFTER LAPAROSCOPIC CHOLECYSTECTOMY:
A PROSPECTIVE STUDY WITH A MINIMUM FOLLOW-UP OF 3
YEARS. Cetta F., Baldi C., Montalto G, Zuckermann M., Gori M., Piro P.,
°Cariati A., *Garotta F.
GASTROENTEROLOGY 1998 Vol. 114, No. 4
In fact, the long cystic duct can act as a mini-gallbladder and as in the the
main gallbladder lumen gallstones can form and as reported in another
interesting article that could be reported in the reference list (article by
Cariati A et et Gallbladder cancers etc etc 2014) long - standing gallstones
promote gallbladder cancer formation (as reported by Diehl and Lowenfels:
- Diehl AK. Gallstone size and the risk of gallbladder cancer. JAMA 1983;
250:2323–2326.
- Lowenfels AB, Maisonneuve P, Boyle P, Zatonski WA. Epidemiology of
gallbladder cancer. Hepatogastroenterology 1999; 46:1529–1532
according to the sequence dysplasia -cancer described By Albores-Saavedra
and
recently by Jain K et al Sequential occurence of preneoplastic lesions and
accumulation of loss of heterozygosity in .. Annals of surgery 2014 doi: 10.1097
/SLA.0000000000000495.
Another point to discuss is: How long will the cystic duct be left ? Reporting
literature data it could be 0,5 - 1 cm
At the end: In case of T2 of cystic duct, as it came from the gallbladder,
and it could be considered as a gallbladder cancer, lymphectomy of hepatic
pedicle and resection of gallbladder bed (Hepatic segment 4 b and hepatic
segment 5 inferior appear to be right).
Level of interest: An article of outstanding merit and interest in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
'I declare that I have no competing interests'
Reviewer's report
Title:Adenocarcinoma developed from remnant cystic duct after cholecystectomy
Version:3Date:22 July 2014
Reviewer: Andrea Cariati
Reviewer's report:
To authors: to improve the discussion chapter reporting these debate:
The long cystic duct stump is a site where gallstones can form "de novo" in
fact authors demonstrated gallstones before the onset of the adenocarcinoma
and
it could be useful to report in the references the abstract of Cetta F et al..
Cariati A etc here enclosed in the email
A-518 AGA ABSTRACTS
G2110
ROLE OF BILE ACID PROPHYLAXIS IN THE PREVENTION OF
RECURRENT CHOLESTEROL STONES FORMING IN THE CYSTIC
REMNANT AFTER LAPAROSCOPIC CHOLECYSTECTOMY:
A PROSPECTIVE STUDY WITH A MINIMUM FOLLOW-UP OF 3
YEARS. Cetta F., Baldi C., Montalto G, Zuckermann M., Gori M., Piro P.,
°Cariati A., *Garotta F.
GASTROENTEROLOGY 1998 Vol. 114, No. 4
In fact, the long cystic duct can act as a mini-gallbladder and as in the the
main gallbladder lumen gallstones can form and as reported in another
interesting article that could be reported in the reference list (article by
Cariati A et et Gallbladder cancers etc etc 2014) long - standing gallstones
promote gallbladder cancer formation (as reported by Diehl and Lowenfels:
- Diehl AK. Gallstone size and the risk of gallbladder cancer. JAMA 1983;
250:2323–2326.
- Lowenfels AB, Maisonneuve P, Boyle P, Zatonski WA. Epidemiology of
gallbladder cancer. Hepatogastroenterology 1999; 46:1529–1532
according to the sequence dysplasia -cancer described By Albores-Saavedra
and
recently by Jain K et al Sequential occurence of preneoplastic lesions and
accumulation of loss of heterozygosity in .. Annals of surgery 2014 doi: 10.1097
/SLA.0000000000000495.
Another point to discuss is: How long will the cystic duct be left ? Reporting
literature data it could be 0,5 - 1 cm
At the end: In case of T2 of cystic duct, as it came from the gallbladder,
and it could be considered as a gallbladder cancer, lymphectomy of hepatic
pedicle and resection of gallbladder bed (Hepatic segment 4 b and hepatic
segment 5 inferior appear to be right).
Level of interest: An article of outstanding merit and interest in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
'I declare that I have no competing interests'
Please review this paper.
user
Reviewer's report
Title:Adenocarcinoma developed from remnant cystic duct after cholecystectomy
Version:3Date:22 July 2014
Reviewer: Andrea Cariati
Reviewer's report:
To authors: to improve the discussion chapter reporting these debate:
The long cystic duct stump is a site where gallstones can form "de novo" in
fact authors demonstrated gallstones before the onset of the adenocarcinoma
and
it could be useful to report in the references the abstract of Cetta F et al..
Cariati A etc here enclosed in the email
A-518 AGA ABSTRACTS
G2110
ROLE OF BILE ACID PROPHYLAXIS IN THE PREVENTION OF
RECURRENT CHOLESTEROL STONES FORMING IN THE CYSTIC
REMNANT AFTER LAPAROSCOPIC CHOLECYSTECTOMY:
A PROSPECTIVE STUDY WITH A MINIMUM FOLLOW-UP OF 3
YEARS. Cetta F., Baldi C., Montalto G, Zuckermann M., Gori M., Piro P.,
°Cariati A., *Garotta F.
GASTROENTEROLOGY 1998 Vol. 114, No. 4
In fact, the long cystic duct can act as a mini-gallbladder and as in the the
main gallbladder lumen gallstones can form and as reported in another
interesting article that could be reported in the reference list (article by
Cariati A et et Gallbladder cancers etc etc 2014) long - standing gallstones
promote gallbladder cancer formation (as reported by Diehl and Lowenfels:
- Diehl AK. Gallstone size and the risk of gallbladder cancer. JAMA 1983;
250:2323–2326.
- Lowenfels AB, Maisonneuve P, Boyle P, Zatonski WA. Epidemiology of
gallbladder cancer. Hepatogastroenterology 1999; 46:1529–1532
according to the sequence dysplasia -cancer described By Albores-Saavedra
and
recently by Jain K et al Sequential occurence of preneoplastic lesions and
accumulation of loss of heterozygosity in .. Annals of surgery 2014 doi: 10.1097
/SLA.0000000000000495.
Another point to discuss is: How long will the cystic duct be left ? Reporting
literature data it could be 0,5 - 1 cm
At the end: In case of T2 of cystic duct, as it came from the gallbladder,
and it could be considered as a gallbladder cancer, lymphectomy of hepatic
pedicle and resection of gallbladder bed (Hepatic segment 4 b and hepatic
segment 5 inferior appear to be right).
Level of interest: An article of outstanding merit and interest in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
'I declare that I have no competing interests'
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