Reviewer's report
Title:Adenocarcinoma developed from remnant cystic duct after cholecystectomy
Version:3Date:16 July 2014
Reviewer: Albert Lowenfels
Reviewer's report:
This straight-forward single case report provides details about a rare
complication of a common operation--cholecystectomy. At her original operation
the patient was left with a excessively long segment of the cystic duct with
subsequent development of gallbladder cancer about ten years after the first
operation. Gallstones, a recognized risk factor for gallbladder cancer, were also
identified in the cystic duct prior to the cancer diagnosis.
Comments: 1) Removing a wedge of liver in patients with gallbladder cancer
makes sense, but is it justified when the tumor develops in the retained cystic
duct? Was the tumor in close contact with the liver?
2) Is there a lesson to be learned from this case report? Perhaps it's that the
cystic duct stump should be made as short as possible without impinging on the
common duct in order to avoid developing complications related to stasis of bile
in the retained cystic duct. This point could be to the discussion conclusion.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
I have no competing interests
Reviewer's report
Title:Adenocarcinoma developed from remnant cystic duct after cholecystectomy
Version:3Date:16 July 2014
Reviewer: Albert Lowenfels
Reviewer's report:
This straight-forward single case report provides details about a rare
complication of a common operation--cholecystectomy. At her original operation
the patient was left with a excessively long segment of the cystic duct with
subsequent development of gallbladder cancer about ten years after the first
operation. Gallstones, a recognized risk factor for gallbladder cancer, were also
identified in the cystic duct prior to the cancer diagnosis.
Comments: 1) Removing a wedge of liver in patients with gallbladder cancer
makes sense, but is it justified when the tumor develops in the retained cystic
duct? Was the tumor in close contact with the liver?
2) Is there a lesson to be learned from this case report? Perhaps it's that the
cystic duct stump should be made as short as possible without impinging on the
common duct in order to avoid developing complications related to stasis of bile
in the retained cystic duct. This point could be to the discussion conclusion.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
I have no competing interests
Please review this paper.
user
Reviewer's report
Title:Adenocarcinoma developed from remnant cystic duct after cholecystectomy
Version:3Date:16 July 2014
Reviewer: Albert Lowenfels
Reviewer's report:
This straight-forward single case report provides details about a rare
complication of a common operation--cholecystectomy. At her original operation
the patient was left with a excessively long segment of the cystic duct with
subsequent development of gallbladder cancer about ten years after the first
operation. Gallstones, a recognized risk factor for gallbladder cancer, were also
identified in the cystic duct prior to the cancer diagnosis.
Comments: 1) Removing a wedge of liver in patients with gallbladder cancer
makes sense, but is it justified when the tumor develops in the retained cystic
duct? Was the tumor in close contact with the liver?
2) Is there a lesson to be learned from this case report? Perhaps it's that the
cystic duct stump should be made as short as possible without impinging on the
common duct in order to avoid developing complications related to stasis of bile
in the retained cystic duct. This point could be to the discussion conclusion.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
I have no competing interests
assistant