Reviewer's report
Title:Autophagy and apoptosis-related genes in chronic liver disease and
hepatocellular carcinoma
Version: 3Date:2 July 2012
Reviewer: Muriel Priault
Reviewer's report:
Minor essential revisions:
The authors have convincingly addressed all the concerns raised after the first
review. There are still spelling errors in the material and methods section (1rst
group: 3 femaleS, 2nd group: 2 femaleS, 3rd group: 1 female).
Also, I would recommend that the western blots shown Fig 3 are not cut so close
to the band of interest, notably for Bcl-xL, which undergoes known
post-translational modifications: it seems that depending on the samples, a
slower migrating band appears above the main band. Even if the authors do not
comment on the upper band and do not take it into account in their interpretation,
this visual information is definitely be very valuable for some readers. Please
modify this accordingly.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: Yes, but I do not feel adequately qualified to assess the
statistics.
Reviewer's report
Title:Autophagy and apoptosis-related genes in chronic liver disease and
hepatocellular carcinoma
Version: 3Date:2 July 2012
Reviewer: Muriel Priault
Reviewer's report:
Minor essential revisions:
The authors have convincingly addressed all the concerns raised after the first
review. There are still spelling errors in the material and methods section (1rst
group: 3 femaleS, 2nd group: 2 femaleS, 3rd group: 1 female).
Also, I would recommend that the western blots shown Fig 3 are not cut so close
to the band of interest, notably for Bcl-xL, which undergoes known
post-translational modifications: it seems that depending on the samples, a
slower migrating band appears above the main band. Even if the authors do not
comment on the upper band and do not take it into account in their interpretation,
this visual information is definitely be very valuable for some readers. Please
modify this accordingly.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: Yes, but I do not feel adequately qualified to assess the
statistics.
Please review this paper.
user
Reviewer's report
Title:Autophagy and apoptosis-related genes in chronic liver disease and
hepatocellular carcinoma
Version: 3Date:2 July 2012
Reviewer: Muriel Priault
Reviewer's report:
Minor essential revisions:
The authors have convincingly addressed all the concerns raised after the first
review. There are still spelling errors in the material and methods section (1rst
group: 3 femaleS, 2nd group: 2 femaleS, 3rd group: 1 female).
Also, I would recommend that the western blots shown Fig 3 are not cut so close
to the band of interest, notably for Bcl-xL, which undergoes known
post-translational modifications: it seems that depending on the samples, a
slower migrating band appears above the main band. Even if the authors do not
comment on the upper band and do not take it into account in their interpretation,
this visual information is definitely be very valuable for some readers. Please
modify this accordingly.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: Yes, but I do not feel adequately qualified to assess the
statistics.
assistant