Title: Administration of Probiotics to Healthy Volunteers – Effects on Reactivity of Intestinal
Mucosa and Systemic Leukocytes
Version: 4 Date: 02 Nov 2021
Reviewer's report:
This is a nicely written study showing the beneficial effect of probiotics in heathy subjects. I
have only minor comments:
* Please add sources of probiotics.
* Are there any units to include in Table 2?
* The authors should consider showing representative histology before and after probiotic
administration.
* Please include brief discussion on strain specificity in the effects of probiotics.
* Please include in brief how TNF-alpha stimulation leads to IL-6 secretion in the discussion.
* Please add statistics on Fig. 2b.
Title: Administration of Probiotics to Healthy Volunteers – Effects on Reactivity of Intestinal
Mucosa and Systemic Leukocytes
Version: 4 Date: 02 Nov 2021
Reviewer's report:
This is a nicely written study showing the beneficial effect of probiotics in heathy subjects. I
have only minor comments:
* Please add sources of probiotics.
* Are there any units to include in Table 2?
* The authors should consider showing representative histology before and after probiotic
administration.
* Please include brief discussion on strain specificity in the effects of probiotics.
* Please include in brief how TNF-alpha stimulation leads to IL-6 secretion in the discussion.
* Please add statistics on Fig. 2b.
Please review this paper.
user
Title: Administration of Probiotics to Healthy Volunteers – Effects on Reactivity of Intestinal
Mucosa and Systemic Leukocytes
Version: 4 Date: 02 Nov 2021
Reviewer's report:
This is a nicely written study showing the beneficial effect of probiotics in heathy subjects. I
have only minor comments:
* Please add sources of probiotics.
* Are there any units to include in Table 2?
* The authors should consider showing representative histology before and after probiotic
administration.
* Please include brief discussion on strain specificity in the effects of probiotics.
* Please include in brief how TNF-alpha stimulation leads to IL-6 secretion in the discussion.
* Please add statistics on Fig. 2b.
assistant