Title: Prevalence and Patterns of Peptic Ulcer Disease in Africa: a systematic review and meta-
analysis
Version: 2 Date: 12 Mar 2025
Reviewer's report:
I must begin by congratulating the authors of this paper, as they looked at a subject that has
received very limited attention in the African context.
My general comment is that they should have mentioned if any of these studies were population
or comminty based. Being either prosepctive or retrospective does not matter as much as
knowing if the individauls being sampled were symptomatic.
Secondly, the results on H. pylori need to be clarified. Was this serological diagnosis or by other
means? This matters because, serological prevelence would be higher than modalities looking
at active disease such as UBT, SAT or urease testing. The analysis should therefore take this
into consideration before drawing any conclusions.
Otherwise this is a good paper.
Title: Prevalence and Patterns of Peptic Ulcer Disease in Africa: a systematic review and meta-
analysis
Version: 2 Date: 12 Mar 2025
Reviewer's report:
I must begin by congratulating the authors of this paper, as they looked at a subject that has
received very limited attention in the African context.
My general comment is that they should have mentioned if any of these studies were population
or comminty based. Being either prosepctive or retrospective does not matter as much as
knowing if the individauls being sampled were symptomatic.
Secondly, the results on H. pylori need to be clarified. Was this serological diagnosis or by other
means? This matters because, serological prevelence would be higher than modalities looking
at active disease such as UBT, SAT or urease testing. The analysis should therefore take this
into consideration before drawing any conclusions.
Otherwise this is a good paper.
Please review this paper.
user
Title: Prevalence and Patterns of Peptic Ulcer Disease in Africa: a systematic review and meta-
analysis
Version: 2 Date: 12 Mar 2025
Reviewer's report:
I must begin by congratulating the authors of this paper, as they looked at a subject that has
received very limited attention in the African context.
My general comment is that they should have mentioned if any of these studies were population
or comminty based. Being either prosepctive or retrospective does not matter as much as
knowing if the individauls being sampled were symptomatic.
Secondly, the results on H. pylori need to be clarified. Was this serological diagnosis or by other
means? This matters because, serological prevelence would be higher than modalities looking
at active disease such as UBT, SAT or urease testing. The analysis should therefore take this
into consideration before drawing any conclusions.
Otherwise this is a good paper.
assistant