Reviewer's report
Title:Albumin treatment regimen for type 1 hepatorenal syndrome: a
dose-response meta-analysis
Version:4Date:3 September 2015
Reviewer: Rita Garcia Martinez
Reviewer's report:
I think the revision of the paper has contributed to an improvement of the article
and I want to congratulate the authors for the important work. I believe this is an
important and relevant paper. I just have a discretionary comment.
- An association between HRS reversal and patient’s baseline characteristics
(creatinine, MELD, bilirubin,...) has been consistently reported in previous
studies. However this meta-analysis found no statistical association (creatinine
p=0.054, other variables >0.10). I think that it would be very welcome in the
discussion the author's point of view/interpretation of this fact. Are these factors
not relevant to the outcome?
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
I declare that I have no competing interests.
Reviewer's report
Title:Albumin treatment regimen for type 1 hepatorenal syndrome: a
dose-response meta-analysis
Version:4Date:3 September 2015
Reviewer: Rita Garcia Martinez
Reviewer's report:
I think the revision of the paper has contributed to an improvement of the article
and I want to congratulate the authors for the important work. I believe this is an
important and relevant paper. I just have a discretionary comment.
- An association between HRS reversal and patient’s baseline characteristics
(creatinine, MELD, bilirubin,...) has been consistently reported in previous
studies. However this meta-analysis found no statistical association (creatinine
p=0.054, other variables >0.10). I think that it would be very welcome in the
discussion the author's point of view/interpretation of this fact. Are these factors
not relevant to the outcome?
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
I declare that I have no competing interests.
Please review this paper.
user
Reviewer's report
Title:Albumin treatment regimen for type 1 hepatorenal syndrome: a
dose-response meta-analysis
Version:4Date:3 September 2015
Reviewer: Rita Garcia Martinez
Reviewer's report:
I think the revision of the paper has contributed to an improvement of the article
and I want to congratulate the authors for the important work. I believe this is an
important and relevant paper. I just have a discretionary comment.
- An association between HRS reversal and patient’s baseline characteristics
(creatinine, MELD, bilirubin,...) has been consistently reported in previous
studies. However this meta-analysis found no statistical association (creatinine
p=0.054, other variables >0.10). I think that it would be very welcome in the
discussion the author's point of view/interpretation of this fact. Are these factors
not relevant to the outcome?
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
I declare that I have no competing interests.
assistant