Reviewer's report
Title:Osteoporosis Increases Subsequent Risk of Gallstone: A Nationwide
Population-based Cohort Study
Version:1Date:28 July 2014
Reviewer: Tao-Hsin Tung
Reviewer's report:
Major Compulsory Revisions
Overall comments:
This study explored osteoporosis increases subsequent risk of gallstone based
on the a nationwide population-based cohort study design. The study designs
and methods used are basically appropriate, and the interpretations of the results
are reasonable. However, the introduction and discussion section were
somewhat inadequate. There are several areas where the manuscript needs to
be strengthened.
Specific comments:
Major concerns
1.The introduction reads rather descriptive. For example, it is not clear how the
information presented in the introduction inform the aims of the study.
2.From the epidemiologic viewpoint, there are many confounding factors in the
evidenced-based researches. How the authors deal with associated confounding
factors in this study?
3.Discussion section was too simple. More discussion will be required for each
risk factor based literature review of previous papers reporting risk factors are
required and then, the authors should point will clarify the feature and novel
findings of this study.
4.More discussion regarding the policy implications of their findings would be
important for the use of methodology in health policy making due to NHI research
database was used.
Minor concerns
Quality of written English: Needs some language corrections before being
published.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
'I declare that I have no competing interests'
Reviewer's report
Title:Osteoporosis Increases Subsequent Risk of Gallstone: A Nationwide
Population-based Cohort Study
Version:1Date:28 July 2014
Reviewer: Tao-Hsin Tung
Reviewer's report:
Major Compulsory Revisions
Overall comments:
This study explored osteoporosis increases subsequent risk of gallstone based
on the a nationwide population-based cohort study design. The study designs
and methods used are basically appropriate, and the interpretations of the results
are reasonable. However, the introduction and discussion section were
somewhat inadequate. There are several areas where the manuscript needs to
be strengthened.
Specific comments:
Major concerns
1.The introduction reads rather descriptive. For example, it is not clear how the
information presented in the introduction inform the aims of the study.
2.From the epidemiologic viewpoint, there are many confounding factors in the
evidenced-based researches. How the authors deal with associated confounding
factors in this study?
3.Discussion section was too simple. More discussion will be required for each
risk factor based literature review of previous papers reporting risk factors are
required and then, the authors should point will clarify the feature and novel
findings of this study.
4.More discussion regarding the policy implications of their findings would be
important for the use of methodology in health policy making due to NHI research
database was used.
Minor concerns
Quality of written English: Needs some language corrections before being
published.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
'I declare that I have no competing interests'
Please review this paper.
user
Reviewer's report
Title:Osteoporosis Increases Subsequent Risk of Gallstone: A Nationwide
Population-based Cohort Study
Version:1Date:28 July 2014
Reviewer: Tao-Hsin Tung
Reviewer's report:
Major Compulsory Revisions
Overall comments:
This study explored osteoporosis increases subsequent risk of gallstone based
on the a nationwide population-based cohort study design. The study designs
and methods used are basically appropriate, and the interpretations of the results
are reasonable. However, the introduction and discussion section were
somewhat inadequate. There are several areas where the manuscript needs to
be strengthened.
Specific comments:
Major concerns
1.The introduction reads rather descriptive. For example, it is not clear how the
information presented in the introduction inform the aims of the study.
2.From the epidemiologic viewpoint, there are many confounding factors in the
evidenced-based researches. How the authors deal with associated confounding
factors in this study?
3.Discussion section was too simple. More discussion will be required for each
risk factor based literature review of previous papers reporting risk factors are
required and then, the authors should point will clarify the feature and novel
findings of this study.
4.More discussion regarding the policy implications of their findings would be
important for the use of methodology in health policy making due to NHI research
database was used.
Minor concerns
Quality of written English: Needs some language corrections before being
published.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
'I declare that I have no competing interests'
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