Reviewer's report
Title:Outcome of gastric emptying and gastrointestinal symptoms after liver
transplantation for hereditary transthyretin amyloidosis
Version:1Date:29 October 2014
Reviewer: Anders Rönnblom
Reviewer's report:
Major Compulsory Revisions
The major problem with this report is the claim to describe a course in a group of
patients for at least 5 years, when only less than a third of those included from
the beginning are followed all the way. (Figure 2). This opposition is supported by
the fact that in the part of the study where drop outs are less prevalent (Figure 3),
the results are different.
This problem could easily be solved be restricting the analysis to the patients that
were followed during the whole study period.
The observation that there is a relation between the use of loperamide and the
Lower GI score (Tab 3) should no be interpretated as loperamide beeing the
cause of the intestinal symptoms, but the oppositeö.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
i declare that I have no competing interests'
Reviewer's report
Title:Outcome of gastric emptying and gastrointestinal symptoms after liver
transplantation for hereditary transthyretin amyloidosis
Version:1Date:29 October 2014
Reviewer: Anders Rönnblom
Reviewer's report:
Major Compulsory Revisions
The major problem with this report is the claim to describe a course in a group of
patients for at least 5 years, when only less than a third of those included from
the beginning are followed all the way. (Figure 2). This opposition is supported by
the fact that in the part of the study where drop outs are less prevalent (Figure 3),
the results are different.
This problem could easily be solved be restricting the analysis to the patients that
were followed during the whole study period.
The observation that there is a relation between the use of loperamide and the
Lower GI score (Tab 3) should no be interpretated as loperamide beeing the
cause of the intestinal symptoms, but the oppositeö.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
i declare that I have no competing interests'
Please review this paper.
user
Reviewer's report
Title:Outcome of gastric emptying and gastrointestinal symptoms after liver
transplantation for hereditary transthyretin amyloidosis
Version:1Date:29 October 2014
Reviewer: Anders Rönnblom
Reviewer's report:
Major Compulsory Revisions
The major problem with this report is the claim to describe a course in a group of
patients for at least 5 years, when only less than a third of those included from
the beginning are followed all the way. (Figure 2). This opposition is supported by
the fact that in the part of the study where drop outs are less prevalent (Figure 3),
the results are different.
This problem could easily be solved be restricting the analysis to the patients that
were followed during the whole study period.
The observation that there is a relation between the use of loperamide and the
Lower GI score (Tab 3) should no be interpretated as loperamide beeing the
cause of the intestinal symptoms, but the oppositeö.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
i declare that I have no competing interests'
assistant