Reviewer's report
Title:Multi-susceptibility genes associated with the risk of the development
stages of esophageal squamous cell cancer in Feicheng County
Version: 2Date:9 April 2011
Reviewer: Elias Zintzaras
Reviewer's report:
The paper is acceptable for publication, but, the authors sould recalaculate the
sample size considering the disease prevelance, the observed minor allele
frequency, a moderate genetic risk effect (OR=1.2-1.3), P-value=0.05 and
1-b=0.80. Then, the posterior power may be calculated.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
'I declare that I have no competing interests'
Reviewer's report
Title:Multi-susceptibility genes associated with the risk of the development
stages of esophageal squamous cell cancer in Feicheng County
Version: 2Date:9 April 2011
Reviewer: Elias Zintzaras
Reviewer's report:
The paper is acceptable for publication, but, the authors sould recalaculate the
sample size considering the disease prevelance, the observed minor allele
frequency, a moderate genetic risk effect (OR=1.2-1.3), P-value=0.05 and
1-b=0.80. Then, the posterior power may be calculated.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
'I declare that I have no competing interests'
Please review this paper.
user
Reviewer's report
Title:Multi-susceptibility genes associated with the risk of the development
stages of esophageal squamous cell cancer in Feicheng County
Version: 2Date:9 April 2011
Reviewer: Elias Zintzaras
Reviewer's report:
The paper is acceptable for publication, but, the authors sould recalaculate the
sample size considering the disease prevelance, the observed minor allele
frequency, a moderate genetic risk effect (OR=1.2-1.3), P-value=0.05 and
1-b=0.80. Then, the posterior power may be calculated.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
'I declare that I have no competing interests'
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