Reviewer's report
Title:Gastrinoma and neurofibromatosis type 2: the first case report and review
of the literature.
Version:2Date:2 March 2014
Reviewer: Gabriele Capurso
Reviewer's report:
Massironi et al. report a case of association between a sporadic Gastrinoma
(although the suspect of a MEN1 is discussed) and a NF2 syndrome.
The paper is clearly presented. I am just not convinced about the clinical
relevance, as there are no specific data here supporting an association which is
not merely occasional.
Minor revisions:
- Page 4: It is arguable that ZES is the commonest functional PETs (it is in MEN1
maybe, but not overall).
- Page 4: the commonest primary localization of gstrinomas is in the
peripancreatic duodenal wall, not in the pancreas! (please see reviews from
Norton and Jensen).
English needs revision.
Level of interest: An article of limited interest
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
I have no competing interests.
Reviewer's report
Title:Gastrinoma and neurofibromatosis type 2: the first case report and review
of the literature.
Version:2Date:2 March 2014
Reviewer: Gabriele Capurso
Reviewer's report:
Massironi et al. report a case of association between a sporadic Gastrinoma
(although the suspect of a MEN1 is discussed) and a NF2 syndrome.
The paper is clearly presented. I am just not convinced about the clinical
relevance, as there are no specific data here supporting an association which is
not merely occasional.
Minor revisions:
- Page 4: It is arguable that ZES is the commonest functional PETs (it is in MEN1
maybe, but not overall).
- Page 4: the commonest primary localization of gstrinomas is in the
peripancreatic duodenal wall, not in the pancreas! (please see reviews from
Norton and Jensen).
English needs revision.
Level of interest: An article of limited interest
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
I have no competing interests.
Please review this paper.
user
Reviewer's report
Title:Gastrinoma and neurofibromatosis type 2: the first case report and review
of the literature.
Version:2Date:2 March 2014
Reviewer: Gabriele Capurso
Reviewer's report:
Massironi et al. report a case of association between a sporadic Gastrinoma
(although the suspect of a MEN1 is discussed) and a NF2 syndrome.
The paper is clearly presented. I am just not convinced about the clinical
relevance, as there are no specific data here supporting an association which is
not merely occasional.
Minor revisions:
- Page 4: It is arguable that ZES is the commonest functional PETs (it is in MEN1
maybe, but not overall).
- Page 4: the commonest primary localization of gstrinomas is in the
peripancreatic duodenal wall, not in the pancreas! (please see reviews from
Norton and Jensen).
English needs revision.
Level of interest: An article of limited interest
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
I have no competing interests.
assistant