Reviewer's report 
 Decreased Expression of Cytochrome P450 Protein in Non-Malignant Colonic Tissue of Title: 
Patients with Colonic Adenoma 
 2  4 October 2005 Version: Date: 
 james Hardwick Reviewer: 
Reviewer's report: 
General 
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Major Compulsory Revisions (that the author must respond to before a decision on publication can 
be reached) 
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Minor Essential Revisions (such as missing labels on figures, or the wrong use of a term, which the 
author can be trusted to correct) 
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Discretionary Revisions (which the author can choose to ignore) 
The authors should eliminate Fig 1A and label Fig 1B with the gene being detected by PCR. 
 Accept after discretionary revisions What next?: 
 An article of importance in its field Level of interest: 
 Acceptable Quality of written English: 
 No Statistical review: 
Declaration of competing interests: 
I declare that I have no competing interests 
Reviewer's report 
 Decreased Expression of Cytochrome P450 Protein in Non-Malignant Colonic Tissue of Title: 
Patients with Colonic Adenoma 
 2  4 October 2005 Version: Date: 
 james Hardwick Reviewer: 
Reviewer's report: 
General 
------------------------------------------------------------------------------- 
Major Compulsory Revisions (that the author must respond to before a decision on publication can 
be reached) 
------------------------------------------------------------------------------- 
Minor Essential Revisions (such as missing labels on figures, or the wrong use of a term, which the 
author can be trusted to correct) 
------------------------------------------------------------------------------- 
Discretionary Revisions (which the author can choose to ignore) 
The authors should eliminate Fig 1A and label Fig 1B with the gene being detected by PCR. 
 Accept after discretionary revisions What next?: 
 An article of importance in its field Level of interest: 
 Acceptable Quality of written English: 
 No Statistical review: 
Declaration of competing interests: 
I declare that I have no competing interests 
Please review this paper.
user
Reviewer's report 
 Decreased Expression of Cytochrome P450 Protein in Non-Malignant Colonic Tissue of Title: 
Patients with Colonic Adenoma 
 2  4 October 2005 Version: Date: 
 james Hardwick Reviewer: 
Reviewer's report: 
General 
------------------------------------------------------------------------------- 
Major Compulsory Revisions (that the author must respond to before a decision on publication can 
be reached) 
------------------------------------------------------------------------------- 
Minor Essential Revisions (such as missing labels on figures, or the wrong use of a term, which the 
author can be trusted to correct) 
------------------------------------------------------------------------------- 
Discretionary Revisions (which the author can choose to ignore) 
The authors should eliminate Fig 1A and label Fig 1B with the gene being detected by PCR. 
 Accept after discretionary revisions What next?: 
 An article of importance in its field Level of interest: 
 Acceptable Quality of written English: 
 No Statistical review: 
Declaration of competing interests: 
I declare that I have no competing interests 
assistant