Reviewer's report
Title:Dose-dependent effects of lesogaberan on reflux measures in patients with
refractory gastroesophageal reflux disease: a randomized, placebo-controlled
study
Version:2Date:14 April 2014
Reviewer: Joaquim Moraes-Filho
Reviewer's report:
The paper is interesting and well conducted.
The authors' reply to the Editor comments were satisfactory answered, though
there is a point which deserves minor essential revision:
"Proton pump inhibitors (PPI) partial responders" are mentioned in the
manuscript. Although the differences among PPIs are small under the clinical
aspect, it would be advisable to mention which PPI were used as well as their
dosage.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: Yes, but I do not feel adequately qualified to assess the
statistics.
Declaration of competing interests:
Competing interests (past five years):
Advisory consulting board of: Astra-zeneca, Reckit-Benckiser, Takeda
Reviewer's report
Title:Dose-dependent effects of lesogaberan on reflux measures in patients with
refractory gastroesophageal reflux disease: a randomized, placebo-controlled
study
Version:2Date:14 April 2014
Reviewer: Joaquim Moraes-Filho
Reviewer's report:
The paper is interesting and well conducted.
The authors' reply to the Editor comments were satisfactory answered, though
there is a point which deserves minor essential revision:
"Proton pump inhibitors (PPI) partial responders" are mentioned in the
manuscript. Although the differences among PPIs are small under the clinical
aspect, it would be advisable to mention which PPI were used as well as their
dosage.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: Yes, but I do not feel adequately qualified to assess the
statistics.
Declaration of competing interests:
Competing interests (past five years):
Advisory consulting board of: Astra-zeneca, Reckit-Benckiser, Takeda
Please review this paper.
user
Reviewer's report
Title:Dose-dependent effects of lesogaberan on reflux measures in patients with
refractory gastroesophageal reflux disease: a randomized, placebo-controlled
study
Version:2Date:14 April 2014
Reviewer: Joaquim Moraes-Filho
Reviewer's report:
The paper is interesting and well conducted.
The authors' reply to the Editor comments were satisfactory answered, though
there is a point which deserves minor essential revision:
"Proton pump inhibitors (PPI) partial responders" are mentioned in the
manuscript. Although the differences among PPIs are small under the clinical
aspect, it would be advisable to mention which PPI were used as well as their
dosage.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: Yes, but I do not feel adequately qualified to assess the
statistics.
Declaration of competing interests:
Competing interests (past five years):
Advisory consulting board of: Astra-zeneca, Reckit-Benckiser, Takeda
assistant