Title: Effect of Skeletal Muscle Index on Post-embolization Syndrome of Hepatocellular
Carcinoma after Transarterial Chemoembolization
Version: 3 Date: 20 Jul 2024
Reviewer's report:
This manuscript showed a possible relationship between low SMI and the development of PES.
I have some suggestions.
1. The prevalence of PES was relatively high in this study. The detailed symptoms or signs for
the diagnosis of PES should be described (i.e., fever, the severity of pain, CRP levels). PES might
be further stratified according to the severity of symptoms, and I suggest additional analyses
based on this stratification.
2. Furthermore, the manuscript does not discuss a possible mechanism for the relationship
between low SMI and the development of PES. This should be addressed in the discussion
section.
Title: Effect of Skeletal Muscle Index on Post-embolization Syndrome of Hepatocellular
Carcinoma after Transarterial Chemoembolization
Version: 3 Date: 20 Jul 2024
Reviewer's report:
This manuscript showed a possible relationship between low SMI and the development of PES.
I have some suggestions.
1. The prevalence of PES was relatively high in this study. The detailed symptoms or signs for
the diagnosis of PES should be described (i.e., fever, the severity of pain, CRP levels). PES might
be further stratified according to the severity of symptoms, and I suggest additional analyses
based on this stratification.
2. Furthermore, the manuscript does not discuss a possible mechanism for the relationship
between low SMI and the development of PES. This should be addressed in the discussion
section.
Please review this paper.
user
Title: Effect of Skeletal Muscle Index on Post-embolization Syndrome of Hepatocellular
Carcinoma after Transarterial Chemoembolization
Version: 3 Date: 20 Jul 2024
Reviewer's report:
This manuscript showed a possible relationship between low SMI and the development of PES.
I have some suggestions.
1. The prevalence of PES was relatively high in this study. The detailed symptoms or signs for
the diagnosis of PES should be described (i.e., fever, the severity of pain, CRP levels). PES might
be further stratified according to the severity of symptoms, and I suggest additional analyses
based on this stratification.
2. Furthermore, the manuscript does not discuss a possible mechanism for the relationship
between low SMI and the development of PES. This should be addressed in the discussion
section.
assistant