Title: Prevalence of vomiting and nausea and associated factors after chronic and acute gluten
exposure in celiac disease
Version: 1 Date: 24 Jul 2023
Reviewer:  Anil K. Verma
Reviewer's report:
Comment#1: I do not understand the term chronic and acute gluten exposure. Neither their
definition was given. I request an explanation of what is chronic gluten exposure and Acute
gluten re-exposure.
Comment#2: Why a confirmed celiac patient would be subjected to a gluten challenge? Is it a
general diagnostic practice or it was done just to see the impact of gluten exposure in treated
CD patients?
Comment#3: This manuscript is poorly organized. The Material and Methods section contains
the results of the study. Please shift the result part in the result section.
Comment#4: Study analysis looks like an expansion of Material and methods it should come
just after methods.
Comment#5: Please Mention the full form of SPSS
Comment#6: In the whole methodology, Chronic gluten exposure and   Acute gluten re-exposure
section. I did not find how gluten exposure was given to patients; or how much gluten was
provided to consume. In the absence of this data, I cannot comment on the results.
Comment#7: The conclusions of the study should also provide the precise prevalence of both
the conditions estimated from the study.
Title: Prevalence of vomiting and nausea and associated factors after chronic and acute gluten
exposure in celiac disease
Version: 1 Date: 24 Jul 2023
Reviewer:  Anil K. Verma
Reviewer's report:
Comment#1: I do not understand the term chronic and acute gluten exposure. Neither their
definition was given. I request an explanation of what is chronic gluten exposure and Acute
gluten re-exposure.
Comment#2: Why a confirmed celiac patient would be subjected to a gluten challenge? Is it a
general diagnostic practice or it was done just to see the impact of gluten exposure in treated
CD patients?
Comment#3: This manuscript is poorly organized. The Material and Methods section contains
the results of the study. Please shift the result part in the result section.
Comment#4: Study analysis looks like an expansion of Material and methods it should come
just after methods.
Comment#5: Please Mention the full form of SPSS
Comment#6: In the whole methodology, Chronic gluten exposure and   Acute gluten re-exposure
section. I did not find how gluten exposure was given to patients; or how much gluten was
provided to consume. In the absence of this data, I cannot comment on the results.
Comment#7: The conclusions of the study should also provide the precise prevalence of both
the conditions estimated from the study.
Please review this paper.
user
Title: Prevalence of vomiting and nausea and associated factors after chronic and acute gluten
exposure in celiac disease
Version: 1 Date: 24 Jul 2023
Reviewer:  Anil K. Verma
Reviewer's report:
Comment#1: I do not understand the term chronic and acute gluten exposure. Neither their
definition was given. I request an explanation of what is chronic gluten exposure and Acute
gluten re-exposure.
Comment#2: Why a confirmed celiac patient would be subjected to a gluten challenge? Is it a
general diagnostic practice or it was done just to see the impact of gluten exposure in treated
CD patients?
Comment#3: This manuscript is poorly organized. The Material and Methods section contains
the results of the study. Please shift the result part in the result section.
Comment#4: Study analysis looks like an expansion of Material and methods it should come
just after methods.
Comment#5: Please Mention the full form of SPSS
Comment#6: In the whole methodology, Chronic gluten exposure and   Acute gluten re-exposure
section. I did not find how gluten exposure was given to patients; or how much gluten was
provided to consume. In the absence of this data, I cannot comment on the results.
Comment#7: The conclusions of the study should also provide the precise prevalence of both
the conditions estimated from the study.
assistant