Title: The interaction effect between childhood trauma and negative events during adulthood
on development and severity of irritable bowel syndrome
Version: 1 Date: 26 Nov 2024
Reviewer's report:
Irritable bowel syndrome is a pressing issue in modern medicine. It is widely recognized that
IBS has a negative impact on patients' quality of life and has a significant socioeconomic burden
of the disease. Therefore it is important to study the factors that contribute to the development
and persistence of symptoms of the disease. It is well known that psychological factors such as
stress and adverse events in early life are often associated with IBS. However  this issue remains
incompletely understood. This article is of high scientific interest and practical significance. The
design of the work is well planned, the methods allow solving all the problems. The goal of the
study has been achieved, the conclusions are logical and justified. I recommend accepting the
article for publication.
Title: The interaction effect between childhood trauma and negative events during adulthood
on development and severity of irritable bowel syndrome
Version: 1 Date: 26 Nov 2024
Reviewer's report:
Irritable bowel syndrome is a pressing issue in modern medicine. It is widely recognized that
IBS has a negative impact on patients' quality of life and has a significant socioeconomic burden
of the disease. Therefore it is important to study the factors that contribute to the development
and persistence of symptoms of the disease. It is well known that psychological factors such as
stress and adverse events in early life are often associated with IBS. However  this issue remains
incompletely understood. This article is of high scientific interest and practical significance. The
design of the work is well planned, the methods allow solving all the problems. The goal of the
study has been achieved, the conclusions are logical and justified. I recommend accepting the
article for publication.
Please review this paper.
user
Title: The interaction effect between childhood trauma and negative events during adulthood
on development and severity of irritable bowel syndrome
Version: 1 Date: 26 Nov 2024
Reviewer's report:
Irritable bowel syndrome is a pressing issue in modern medicine. It is widely recognized that
IBS has a negative impact on patients' quality of life and has a significant socioeconomic burden
of the disease. Therefore it is important to study the factors that contribute to the development
and persistence of symptoms of the disease. It is well known that psychological factors such as
stress and adverse events in early life are often associated with IBS. However  this issue remains
incompletely understood. This article is of high scientific interest and practical significance. The
design of the work is well planned, the methods allow solving all the problems. The goal of the
study has been achieved, the conclusions are logical and justified. I recommend accepting the
article for publication.
assistant