Reviewer’s report
Title: 
Abdominal pain in patients with inflammatory bowel disease – Association with single-nucleotide
polymorphisms prevalent in irritable bowel syndrome and clinical management
Version: 
0 
Date: 
06 Dec 2019
Reviewer: 
Aysegül Aksan
Reviewer's report:
This is a clearly written manuscript with interesting results through good methodology. I would only
recommend authors to give the explanations under the tables to make them more understandable
(statistical test which has been used etc...). The other thing is they have to check the structure of the text, I
think the order of the text and tables are mixed somehow ( the nasmes of the tables are under them also
they are cutted strangely by the page...)
Are the methods appropriate and well described?
If not, please specify what is required in your comments to the authors.
Yes
Does the work include the necessary controls?
If not, please specify which controls are required in your comments to the authors.
Yes
Are the conclusions drawn adequately supported by the data shown?
If not, please explain in your comments to the authors.
Yes
Are you able to assess any statistics in the manuscript or would you recommend an additional
statistical review?
If an additional statistical review is recommended, please specify what aspects require further assessment
in your comments to the editors.
I am able to assess the statistics
Quality of written English
Please indicate the quality of language in the manuscript:
Needs some language corrections before being published
Declaration of competing interests
Please complete a declaration of competing interests, considering the following questions:
1
. 
Have you in the past five years received reimbursements, fees, funding, or salary from an
organisation that may in any way gain or lose financially from the publication of this manuscript,
either now or in the future?
2
. 
Do you hold any stocks or shares in an organisation that may in any way gain or lose financially
from the publication of this manuscript, either now or in the future?
3
. 
Do you hold or are you currently applying for any patents relating to the content of the manuscript?
4
. 
Have you received reimbursements, fees, funding, or salary from an organization that holds or has
applied for patents relating to the content of the manuscript?
5
. 
Do you have any other financial competing interests?
6
. 
Do you have any non-financial competing interests in relation to this paper?
If you can answer no to all of the above, write 'I declare that I have no competing interests' below. If your
reply is yes to any, please give details below.
I declare that I have no competing interests
I agree to the open peer review policy of the journal. I understand that my name will be included on my
report to the authors and, if the manuscript is accepted for publication, my named report including any
attachments I upload will be posted on the website along with the authors' responses. I agree for my report
to be made available under an Open Access Creative Commons CC-BY license
(
http://creativecommons.org/licenses/by/4.0/
). I understand that any comments which I do not wish to be
included in my named report can be included as confidential comments to the editors, which will not be
published.
I agree to the open peer review policy of the journal
Reviewer’s report
Title: 
Abdominal pain in patients with inflammatory bowel disease – Association with single-nucleotide
polymorphisms prevalent in irritable bowel syndrome and clinical management
Version: 
0 
Date: 
06 Dec 2019
Reviewer: 
Aysegül Aksan
Reviewer's report:
This is a clearly written manuscript with interesting results through good methodology. I would only
recommend authors to give the explanations under the tables to make them more understandable
(statistical test which has been used etc...). The other thing is they have to check the structure of the text, I
think the order of the text and tables are mixed somehow ( the nasmes of the tables are under them also
they are cutted strangely by the page...)
Are the methods appropriate and well described?
If not, please specify what is required in your comments to the authors.
Yes
Does the work include the necessary controls?
If not, please specify which controls are required in your comments to the authors.
Yes
Are the conclusions drawn adequately supported by the data shown?
If not, please explain in your comments to the authors.
Yes
Are you able to assess any statistics in the manuscript or would you recommend an additional
statistical review?
If an additional statistical review is recommended, please specify what aspects require further assessment
in your comments to the editors.
I am able to assess the statistics
Quality of written English
Please indicate the quality of language in the manuscript:
Needs some language corrections before being published
Declaration of competing interests
Please complete a declaration of competing interests, considering the following questions:
1
. 
Have you in the past five years received reimbursements, fees, funding, or salary from an
organisation that may in any way gain or lose financially from the publication of this manuscript,
either now or in the future?
2
. 
Do you hold any stocks or shares in an organisation that may in any way gain or lose financially
from the publication of this manuscript, either now or in the future?
3
. 
Do you hold or are you currently applying for any patents relating to the content of the manuscript?
4
. 
Have you received reimbursements, fees, funding, or salary from an organization that holds or has
applied for patents relating to the content of the manuscript?
5
. 
Do you have any other financial competing interests?
6
. 
Do you have any non-financial competing interests in relation to this paper?
If you can answer no to all of the above, write 'I declare that I have no competing interests' below. If your
reply is yes to any, please give details below.
I declare that I have no competing interests
I agree to the open peer review policy of the journal. I understand that my name will be included on my
report to the authors and, if the manuscript is accepted for publication, my named report including any
attachments I upload will be posted on the website along with the authors' responses. I agree for my report
to be made available under an Open Access Creative Commons CC-BY license
(
http://creativecommons.org/licenses/by/4.0/
). I understand that any comments which I do not wish to be
included in my named report can be included as confidential comments to the editors, which will not be
published.
I agree to the open peer review policy of the journal
Please review this paper.
user
Reviewer’s report
Title: 
Abdominal pain in patients with inflammatory bowel disease – Association with single-nucleotide
polymorphisms prevalent in irritable bowel syndrome and clinical management
Version: 
0 
Date: 
06 Dec 2019
Reviewer: 
Aysegül Aksan
Reviewer's report:
This is a clearly written manuscript with interesting results through good methodology. I would only
recommend authors to give the explanations under the tables to make them more understandable
(statistical test which has been used etc...). The other thing is they have to check the structure of the text, I
think the order of the text and tables are mixed somehow ( the nasmes of the tables are under them also
they are cutted strangely by the page...)
Are the methods appropriate and well described?
If not, please specify what is required in your comments to the authors.
Yes
Does the work include the necessary controls?
If not, please specify which controls are required in your comments to the authors.
Yes
Are the conclusions drawn adequately supported by the data shown?
If not, please explain in your comments to the authors.
Yes
Are you able to assess any statistics in the manuscript or would you recommend an additional
statistical review?
If an additional statistical review is recommended, please specify what aspects require further assessment
in your comments to the editors.
I am able to assess the statistics
Quality of written English
Please indicate the quality of language in the manuscript:
Needs some language corrections before being published
Declaration of competing interests
Please complete a declaration of competing interests, considering the following questions:
1
. 
Have you in the past five years received reimbursements, fees, funding, or salary from an
organisation that may in any way gain or lose financially from the publication of this manuscript,
either now or in the future?
2
. 
Do you hold any stocks or shares in an organisation that may in any way gain or lose financially
from the publication of this manuscript, either now or in the future?
3
. 
Do you hold or are you currently applying for any patents relating to the content of the manuscript?
4
. 
Have you received reimbursements, fees, funding, or salary from an organization that holds or has
applied for patents relating to the content of the manuscript?
5
. 
Do you have any other financial competing interests?
6
. 
Do you have any non-financial competing interests in relation to this paper?
If you can answer no to all of the above, write 'I declare that I have no competing interests' below. If your
reply is yes to any, please give details below.
I declare that I have no competing interests
I agree to the open peer review policy of the journal. I understand that my name will be included on my
report to the authors and, if the manuscript is accepted for publication, my named report including any
attachments I upload will be posted on the website along with the authors' responses. I agree for my report
to be made available under an Open Access Creative Commons CC-BY license
(
http://creativecommons.org/licenses/by/4.0/
). I understand that any comments which I do not wish to be
included in my named report can be included as confidential comments to the editors, which will not be
published.
I agree to the open peer review policy of the journal
assistant