Reviewer's report
Title:Statin use is associated with a reduced incidence of colorectal cancer: a
colonoscopy-controlled case-control study
Version: 2Date:6 March 2012
Reviewer: Trine Lembrecht Lembrecht Jorgensen
Reviewer's report:
This is still a nicely conducted, though small, case-control study. The question
asked by the authors is well defined, the methods seem appropriate and are well
described. I think the new table 2 has improved the manuscript, and the
explaining of post-colonoscopy including of cases is also beneficial.
I still don’t think the study results reflect the true association of statin use and crc,
but as the authors point out: those are their results, perhaps due to low sample
size.
Overall, I think the manuscript has improved markedly.
Discretionary revisions:
Abstract, results & tables. No need for p values where confidence intervals are
provided as these are much more informative.
Level of interest: An article of limited interest
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I have no competing interests
Reviewer's report
Title:Statin use is associated with a reduced incidence of colorectal cancer: a
colonoscopy-controlled case-control study
Version: 2Date:6 March 2012
Reviewer: Trine Lembrecht Lembrecht Jorgensen
Reviewer's report:
This is still a nicely conducted, though small, case-control study. The question
asked by the authors is well defined, the methods seem appropriate and are well
described. I think the new table 2 has improved the manuscript, and the
explaining of post-colonoscopy including of cases is also beneficial.
I still don’t think the study results reflect the true association of statin use and crc,
but as the authors point out: those are their results, perhaps due to low sample
size.
Overall, I think the manuscript has improved markedly.
Discretionary revisions:
Abstract, results & tables. No need for p values where confidence intervals are
provided as these are much more informative.
Level of interest: An article of limited interest
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I have no competing interests
Please review this paper.
user
Reviewer's report
Title:Statin use is associated with a reduced incidence of colorectal cancer: a
colonoscopy-controlled case-control study
Version: 2Date:6 March 2012
Reviewer: Trine Lembrecht Lembrecht Jorgensen
Reviewer's report:
This is still a nicely conducted, though small, case-control study. The question
asked by the authors is well defined, the methods seem appropriate and are well
described. I think the new table 2 has improved the manuscript, and the
explaining of post-colonoscopy including of cases is also beneficial.
I still don’t think the study results reflect the true association of statin use and crc,
but as the authors point out: those are their results, perhaps due to low sample
size.
Overall, I think the manuscript has improved markedly.
Discretionary revisions:
Abstract, results & tables. No need for p values where confidence intervals are
provided as these are much more informative.
Level of interest: An article of limited interest
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I have no competing interests
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