Title: Analysis of factors related to recanalization of portal vein thrombosis in liver cirrhosis:
a retrospective cohort study
Version: 1 Date: 24 Jan 2024
Reviewer's report:
This study reports the predictive factors of PVT recanalization in cirrhosis. Anticoagulant
therapy may increase the PVT recanalization rate and reduce the PVT progression rate without
increasing the bleeding rate. But there are some problems in the manuscript.
1.Mentioned in the abstract that We aimed to further explore the predictors of recanalization
in cirrhotic PVT to facilitate accurate prediction of patients' clinical status and timely initiation
of appropriate treatment and interventions. However, the article did not cover the timing and
duration of anticoagulation therapy. How to grasp the timing and duration of anticoagulation
during treatment?
2.The exclusion criteria include Malignancy-related portal vein thrombosis, but what is the data
on History of Hepatic carcinom in Table 1? How to explain? Please check the data for accuracy.
3.Studies have shown that partial portal vein thrombosis has the possibility of spontaneous
dissolution. Was this the case in your study?
4.In patients undergoing anticoagulation therapy, is it an acute thrombosis or a chronic
thrombosis? What is the outcome of the separation?
5.The formatting problem is serious. Please check the formatting and punctuation in the text
and charts.
6.Please correct the grammatical problems in the language and sentences in the accepted
manuscript, such as in the abstract: We also further investigated the benefits and risks of
anticoagulation therapy in patients with cirrhotic PVT are further investigated. Can be revised
to: We further investigated the benefits and risks of anticoagulation therapy in cirrhotic patients
with PVT.
Title: Analysis of factors related to recanalization of portal vein thrombosis in liver cirrhosis:
a retrospective cohort study
Version: 1 Date: 24 Jan 2024
Reviewer's report:
This study reports the predictive factors of PVT recanalization in cirrhosis. Anticoagulant
therapy may increase the PVT recanalization rate and reduce the PVT progression rate without
increasing the bleeding rate. But there are some problems in the manuscript.
1.Mentioned in the abstract that We aimed to further explore the predictors of recanalization
in cirrhotic PVT to facilitate accurate prediction of patients' clinical status and timely initiation
of appropriate treatment and interventions. However, the article did not cover the timing and
duration of anticoagulation therapy. How to grasp the timing and duration of anticoagulation
during treatment?
2.The exclusion criteria include Malignancy-related portal vein thrombosis, but what is the data
on History of Hepatic carcinom in Table 1? How to explain? Please check the data for accuracy.
3.Studies have shown that partial portal vein thrombosis has the possibility of spontaneous
dissolution. Was this the case in your study?
4.In patients undergoing anticoagulation therapy, is it an acute thrombosis or a chronic
thrombosis? What is the outcome of the separation?
5.The formatting problem is serious. Please check the formatting and punctuation in the text
and charts.
6.Please correct the grammatical problems in the language and sentences in the accepted
manuscript, such as in the abstract: We also further investigated the benefits and risks of
anticoagulation therapy in patients with cirrhotic PVT are further investigated. Can be revised
to: We further investigated the benefits and risks of anticoagulation therapy in cirrhotic patients
with PVT.
Please review this paper.
user
Title: Analysis of factors related to recanalization of portal vein thrombosis in liver cirrhosis:
a retrospective cohort study
Version: 1 Date: 24 Jan 2024
Reviewer's report:
This study reports the predictive factors of PVT recanalization in cirrhosis. Anticoagulant
therapy may increase the PVT recanalization rate and reduce the PVT progression rate without
increasing the bleeding rate. But there are some problems in the manuscript.
1.Mentioned in the abstract that We aimed to further explore the predictors of recanalization
in cirrhotic PVT to facilitate accurate prediction of patients' clinical status and timely initiation
of appropriate treatment and interventions. However, the article did not cover the timing and
duration of anticoagulation therapy. How to grasp the timing and duration of anticoagulation
during treatment?
2.The exclusion criteria include Malignancy-related portal vein thrombosis, but what is the data
on History of Hepatic carcinom in Table 1? How to explain? Please check the data for accuracy.
3.Studies have shown that partial portal vein thrombosis has the possibility of spontaneous
dissolution. Was this the case in your study?
4.In patients undergoing anticoagulation therapy, is it an acute thrombosis or a chronic
thrombosis? What is the outcome of the separation?
5.The formatting problem is serious. Please check the formatting and punctuation in the text
and charts.
6.Please correct the grammatical problems in the language and sentences in the accepted
manuscript, such as in the abstract: We also further investigated the benefits and risks of
anticoagulation therapy in patients with cirrhotic PVT are further investigated. Can be revised
to: We further investigated the benefits and risks of anticoagulation therapy in cirrhotic patients
with PVT.
assistant