Title: Validation of a new simple scoring system to predict spontaneous bacterial peritonitis in
patients with cirrhosis and ascites
Version: 1 Date: 13 May 2023
Reviewer:  Ahmed Abdel-Razik
Reviewer's report:
Nice work, but the authors may have some drawbacks to be clarified.
1-Recurrence of SBP in this university hospital should be mentioned in the introduction section
(Eur J Gastroenterol Hepatol. 2020 Jun;32(6):718-726. doi:10.1097/MEG.0000000000001578.)
2-Diagnosis of SBP and its variants may need more explanations.
3-The exclusion criteria should be written as follows: (a) patients who had received antibiotic
and/or prophylaxis for SBP before admission; (b) participants who had other causes of
ascites, for example, pancreatitis, peritoneal carcinomatosis, tuberculosis, congestive heart
failure, renal diseases, or hemorrhage into ascites; (c) patients with malignancy; (d) patients
with hemato logical diseases; (e) patients with surgical abdominal interference within 3
months of study entry; (f) participants who had received antiplatelet medications before their
admission; (g) participants who had received bone marrow transplantation or chemotherapy or
radiotherapy 1 month before admission; (h) pregnancy; (i) patients with secondary peritonitis;
(j) immunocompromised patients; (k) patients receiving NSAIDs or contraceptive pills before
hospital admission; (l) bacterial infection other than SBP; (m) patients with conditions associated
with increased MPV, for example, dyslipidemia, thyroid disorders, peripheral vascular disease,
hypertension, and diabetes mellitus; (n) patients with recent hemorrhage; and (o) patients who
had been infused with platelet or blood before their admission.
4-Please for high-resolution figures.
5-Discussion needs more revision.
Title: Validation of a new simple scoring system to predict spontaneous bacterial peritonitis in
patients with cirrhosis and ascites
Version: 1 Date: 13 May 2023
Reviewer:  Ahmed Abdel-Razik
Reviewer's report:
Nice work, but the authors may have some drawbacks to be clarified.
1-Recurrence of SBP in this university hospital should be mentioned in the introduction section
(Eur J Gastroenterol Hepatol. 2020 Jun;32(6):718-726. doi:10.1097/MEG.0000000000001578.)
2-Diagnosis of SBP and its variants may need more explanations.
3-The exclusion criteria should be written as follows: (a) patients who had received antibiotic
and/or prophylaxis for SBP before admission; (b) participants who had other causes of
ascites, for example, pancreatitis, peritoneal carcinomatosis, tuberculosis, congestive heart
failure, renal diseases, or hemorrhage into ascites; (c) patients with malignancy; (d) patients
with hemato logical diseases; (e) patients with surgical abdominal interference within 3
months of study entry; (f) participants who had received antiplatelet medications before their
admission; (g) participants who had received bone marrow transplantation or chemotherapy or
radiotherapy 1 month before admission; (h) pregnancy; (i) patients with secondary peritonitis;
(j) immunocompromised patients; (k) patients receiving NSAIDs or contraceptive pills before
hospital admission; (l) bacterial infection other than SBP; (m) patients with conditions associated
with increased MPV, for example, dyslipidemia, thyroid disorders, peripheral vascular disease,
hypertension, and diabetes mellitus; (n) patients with recent hemorrhage; and (o) patients who
had been infused with platelet or blood before their admission.
4-Please for high-resolution figures.
5-Discussion needs more revision.
Please review this paper.
user
Title: Validation of a new simple scoring system to predict spontaneous bacterial peritonitis in
patients with cirrhosis and ascites
Version: 1 Date: 13 May 2023
Reviewer:  Ahmed Abdel-Razik
Reviewer's report:
Nice work, but the authors may have some drawbacks to be clarified.
1-Recurrence of SBP in this university hospital should be mentioned in the introduction section
(Eur J Gastroenterol Hepatol. 2020 Jun;32(6):718-726. doi:10.1097/MEG.0000000000001578.)
2-Diagnosis of SBP and its variants may need more explanations.
3-The exclusion criteria should be written as follows: (a) patients who had received antibiotic
and/or prophylaxis for SBP before admission; (b) participants who had other causes of
ascites, for example, pancreatitis, peritoneal carcinomatosis, tuberculosis, congestive heart
failure, renal diseases, or hemorrhage into ascites; (c) patients with malignancy; (d) patients
with hemato logical diseases; (e) patients with surgical abdominal interference within 3
months of study entry; (f) participants who had received antiplatelet medications before their
admission; (g) participants who had received bone marrow transplantation or chemotherapy or
radiotherapy 1 month before admission; (h) pregnancy; (i) patients with secondary peritonitis;
(j) immunocompromised patients; (k) patients receiving NSAIDs or contraceptive pills before
hospital admission; (l) bacterial infection other than SBP; (m) patients with conditions associated
with increased MPV, for example, dyslipidemia, thyroid disorders, peripheral vascular disease,
hypertension, and diabetes mellitus; (n) patients with recent hemorrhage; and (o) patients who
had been infused with platelet or blood before their admission.
4-Please for high-resolution figures.
5-Discussion needs more revision.
assistant