Title: Role of Liver Transient Elastography in Detecting Cirrhosis with Esophageal and Gastric
Varices and Evaluating Variceal Severity
Version: 1 Date: 06 Apr 2025
Reviewer:  Billy Siahaan
Reviewer's report:
first of all , congratulations for your research
i would like to comment about your study
1 .  could you describe what classification did you use for  varices grading on your research ?
2.  i think you should mention what health people ( control group) means in your research?  the
people with cirrhosis with out varices or healthy people with out any kind of disease?
3.  could you diverse in your subject , the etiology of cirrhosis , with or with out anti viral ,
because its should be  influence for your result .
4.  I also not so clear what kind of methodology that you use for this study , is this the
retrospective cross sectional study ?  what about the timeline between the endoscopy finding
and transient elastography evaluation ?  did at the same time or different time ? could you more
detail to explained your method
5. " success rate should be higher than 60%, the relative deviation should be less than 33% "  ,
as i know the relative deviation if you mean by that was interquartile range / median ( IQR/M)
should be below 30% not 33 %
6.  In your result i do not see the complete base line characteristic subject in your research.
Could you showed with a good table about variable that really important , for example Trombosit
count , child pugh score etc . Because i think it is very important to know what is the child pugh
category that dominant in your research ,
7. I  am a little bit hesitate about the result of specificity "100" for liver stiffness performance
related to diagnose cirrhosis and varices esophageal, could you explain where did you get this
outstanding number ?
Title: Role of Liver Transient Elastography in Detecting Cirrhosis with Esophageal and Gastric
Varices and Evaluating Variceal Severity
Version: 1 Date: 06 Apr 2025
Reviewer:  Billy Siahaan
Reviewer's report:
first of all , congratulations for your research
i would like to comment about your study
1 .  could you describe what classification did you use for  varices grading on your research ?
2.  i think you should mention what health people ( control group) means in your research?  the
people with cirrhosis with out varices or healthy people with out any kind of disease?
3.  could you diverse in your subject , the etiology of cirrhosis , with or with out anti viral ,
because its should be  influence for your result .
4.  I also not so clear what kind of methodology that you use for this study , is this the
retrospective cross sectional study ?  what about the timeline between the endoscopy finding
and transient elastography evaluation ?  did at the same time or different time ? could you more
detail to explained your method
5. " success rate should be higher than 60%, the relative deviation should be less than 33% "  ,
as i know the relative deviation if you mean by that was interquartile range / median ( IQR/M)
should be below 30% not 33 %
6.  In your result i do not see the complete base line characteristic subject in your research.
Could you showed with a good table about variable that really important , for example Trombosit
count , child pugh score etc . Because i think it is very important to know what is the child pugh
category that dominant in your research ,
7. I  am a little bit hesitate about the result of specificity "100" for liver stiffness performance
related to diagnose cirrhosis and varices esophageal, could you explain where did you get this
outstanding number ?
Please review this paper.
user
Title: Role of Liver Transient Elastography in Detecting Cirrhosis with Esophageal and Gastric
Varices and Evaluating Variceal Severity
Version: 1 Date: 06 Apr 2025
Reviewer:  Billy Siahaan
Reviewer's report:
first of all , congratulations for your research
i would like to comment about your study
1 .  could you describe what classification did you use for  varices grading on your research ?
2.  i think you should mention what health people ( control group) means in your research?  the
people with cirrhosis with out varices or healthy people with out any kind of disease?
3.  could you diverse in your subject , the etiology of cirrhosis , with or with out anti viral ,
because its should be  influence for your result .
4.  I also not so clear what kind of methodology that you use for this study , is this the
retrospective cross sectional study ?  what about the timeline between the endoscopy finding
and transient elastography evaluation ?  did at the same time or different time ? could you more
detail to explained your method
5. " success rate should be higher than 60%, the relative deviation should be less than 33% "  ,
as i know the relative deviation if you mean by that was interquartile range / median ( IQR/M)
should be below 30% not 33 %
6.  In your result i do not see the complete base line characteristic subject in your research.
Could you showed with a good table about variable that really important , for example Trombosit
count , child pugh score etc . Because i think it is very important to know what is the child pugh
category that dominant in your research ,
7. I  am a little bit hesitate about the result of specificity "100" for liver stiffness performance
related to diagnose cirrhosis and varices esophageal, could you explain where did you get this
outstanding number ?
assistant