Title: Liver histology pattern of young patients with inactive chronic hepatitis B virus infection
from a Hospital in South West Nigeria
Version: 5 Date: 29 Sep 2024
Reviewer's report:
- Patient selection: the criteria for defining inactive carriage do not seem to be met in all patients.
- For patients, particularly with fibrosis, elastometry could play an important role. It could help
avoid biopsy
- How do you explain that several patients have hypoalbuminemia? and an increase in ALP?
- Can you better define the different stages in those who have fibrosis or significant
inflammation?
- Interesting study showing that populations in Africa with HBV have a particular profile, and
that they must be taken on a case-by-case basis
Title: Liver histology pattern of young patients with inactive chronic hepatitis B virus infection
from a Hospital in South West Nigeria
Version: 5 Date: 29 Sep 2024
Reviewer's report:
- Patient selection: the criteria for defining inactive carriage do not seem to be met in all patients.
- For patients, particularly with fibrosis, elastometry could play an important role. It could help
avoid biopsy
- How do you explain that several patients have hypoalbuminemia? and an increase in ALP?
- Can you better define the different stages in those who have fibrosis or significant
inflammation?
- Interesting study showing that populations in Africa with HBV have a particular profile, and
that they must be taken on a case-by-case basis
Please review this paper.
user
Title: Liver histology pattern of young patients with inactive chronic hepatitis B virus infection
from a Hospital in South West Nigeria
Version: 5 Date: 29 Sep 2024
Reviewer's report:
- Patient selection: the criteria for defining inactive carriage do not seem to be met in all patients.
- For patients, particularly with fibrosis, elastometry could play an important role. It could help
avoid biopsy
- How do you explain that several patients have hypoalbuminemia? and an increase in ALP?
- Can you better define the different stages in those who have fibrosis or significant
inflammation?
- Interesting study showing that populations in Africa with HBV have a particular profile, and
that they must be taken on a case-by-case basis
assistant