Title: Title: Clinicopathologic characteristics and prognosis of synchronous colorectal cancer:
A retrospective study
Version: 1 Date: 18 Jan 2022
Reviewer's report:
1. although this study concerns a large cohort, 26% of patients are not studied because they are
considered lost to follow-up, well above the less than 10% admitted to validate conclusions. this
loss of follow-up rate is a major limit. this point should at least be mentioned in the discussion.
Response: Thank you for your nice comments. There could be a misunderstanding here. As
shown in Figure 1. 26% patients (621) were excluded because they met the exclusion criteria.
Such as, Patients with any recurrent tumour, familial adenomatous polyposis, or hereditary
nonpolyposis colorectal cancer were excluded. Lost to follow-up data only accounts for a small
part of the exclusion criteria.
i don't agree with your response: 787 (33.6%)patients were excluded for exclusion criteria, of
them 26% (612) for missing data: sa there is a selection bias: only patients corectly followed
were included....this point should at least be mentioned in the discussion.
Title: Title: Clinicopathologic characteristics and prognosis of synchronous colorectal cancer:
A retrospective study
Version: 1 Date: 18 Jan 2022
Reviewer's report:
1. although this study concerns a large cohort, 26% of patients are not studied because they are
considered lost to follow-up, well above the less than 10% admitted to validate conclusions. this
loss of follow-up rate is a major limit. this point should at least be mentioned in the discussion.
Response: Thank you for your nice comments. There could be a misunderstanding here. As
shown in Figure 1. 26% patients (621) were excluded because they met the exclusion criteria.
Such as, Patients with any recurrent tumour, familial adenomatous polyposis, or hereditary
nonpolyposis colorectal cancer were excluded. Lost to follow-up data only accounts for a small
part of the exclusion criteria.
i don't agree with your response: 787 (33.6%)patients were excluded for exclusion criteria, of
them 26% (612) for missing data: sa there is a selection bias: only patients corectly followed
were included....this point should at least be mentioned in the discussion.
Please review this paper.
user
Title: Title: Clinicopathologic characteristics and prognosis of synchronous colorectal cancer:
A retrospective study
Version: 1 Date: 18 Jan 2022
Reviewer's report:
1. although this study concerns a large cohort, 26% of patients are not studied because they are
considered lost to follow-up, well above the less than 10% admitted to validate conclusions. this
loss of follow-up rate is a major limit. this point should at least be mentioned in the discussion.
Response: Thank you for your nice comments. There could be a misunderstanding here. As
shown in Figure 1. 26% patients (621) were excluded because they met the exclusion criteria.
Such as, Patients with any recurrent tumour, familial adenomatous polyposis, or hereditary
nonpolyposis colorectal cancer were excluded. Lost to follow-up data only accounts for a small
part of the exclusion criteria.
i don't agree with your response: 787 (33.6%)patients were excluded for exclusion criteria, of
them 26% (612) for missing data: sa there is a selection bias: only patients corectly followed
were included....this point should at least be mentioned in the discussion.
assistant