Reviewer's report
Title:Role of tight junction proteins in gastroesophageal reflux disease
Version: 1Date:6 July 2012
Reviewer: norimasa yoshida
Reviewer's report:
This paper demonstrates implication of tight junction in GERD.
Which differences are there in the expression of tight junction molecules between
NERD and ERD?
Do these differences have any effect on the pathogenesis of NERD and ERD?
Authors should discuss about these questions.
Which is biopsy sample in Figure 2 taken from, NERD or ERD?
Description in Figure 2 legend(ERD) and Figure 2(NERD) are different.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Reviewer's report
Title:Role of tight junction proteins in gastroesophageal reflux disease
Version: 1Date:6 July 2012
Reviewer: norimasa yoshida
Reviewer's report:
This paper demonstrates implication of tight junction in GERD.
Which differences are there in the expression of tight junction molecules between
NERD and ERD?
Do these differences have any effect on the pathogenesis of NERD and ERD?
Authors should discuss about these questions.
Which is biopsy sample in Figure 2 taken from, NERD or ERD?
Description in Figure 2 legend(ERD) and Figure 2(NERD) are different.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Please review this paper.
user
Reviewer's report
Title:Role of tight junction proteins in gastroesophageal reflux disease
Version: 1Date:6 July 2012
Reviewer: norimasa yoshida
Reviewer's report:
This paper demonstrates implication of tight junction in GERD.
Which differences are there in the expression of tight junction molecules between
NERD and ERD?
Do these differences have any effect on the pathogenesis of NERD and ERD?
Authors should discuss about these questions.
Which is biopsy sample in Figure 2 taken from, NERD or ERD?
Description in Figure 2 legend(ERD) and Figure 2(NERD) are different.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
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