Title: Feasibility and predictors of same-day discharge following endoscopic submucosal
dissection for early esophageal cancer
Version: 1 Date: 28 Apr 2025
Reviewer's report:
The authors presented a study on the feasibility and predictors of same-day discharge following
endoscopic submucosal dissection for early esophageal cancer.
This manuscript is well written and organized. However, this manuscript has few novelties.
Below are the comments and questions.
Major
1. This study focuses on the clinical characteristics to evaluate the feasibility and risk factors
of same-day discharge following esophageal ESD. However, to properly assess feasibility, the
post-discharge clinical course (e.g. symptoms, aspirated pneumonia, the presence of visiting
emergency care unit and readmission to the hospital) should also be discussed.
2. Since the type and dose of sedation used during ESD may influence discharge timing,
these details should be reported. In addition, from previous studies, alcohol abuse is correlated
with unsuccessful sedation. This suggests more sedation needs in the patients with alcohol
abuse, which may affect the total dose of sedation. This hypothesis should be mentioned in the
discussion section.
3. The rate of intraoperative bleeding in this study appears to be higher than that reported
in the previous studies on esophageal ESD. As intraoperative bleeding and perforation also
may influence the decision of SDD following ESD, definition of these terms should be clearly
provided in the manuscript.
Minor
1. In the result section, the number of patients with early esophageal cancer who underwent ESD
was 168. However, in Figure1, the number of patients with early esophageal cancer was 168.
The sentence in the manuscript should be corrected.
Title: Feasibility and predictors of same-day discharge following endoscopic submucosal
dissection for early esophageal cancer
Version: 1 Date: 28 Apr 2025
Reviewer's report:
The authors presented a study on the feasibility and predictors of same-day discharge following
endoscopic submucosal dissection for early esophageal cancer.
This manuscript is well written and organized. However, this manuscript has few novelties.
Below are the comments and questions.
Major
1. This study focuses on the clinical characteristics to evaluate the feasibility and risk factors
of same-day discharge following esophageal ESD. However, to properly assess feasibility, the
post-discharge clinical course (e.g. symptoms, aspirated pneumonia, the presence of visiting
emergency care unit and readmission to the hospital) should also be discussed.
2. Since the type and dose of sedation used during ESD may influence discharge timing,
these details should be reported. In addition, from previous studies, alcohol abuse is correlated
with unsuccessful sedation. This suggests more sedation needs in the patients with alcohol
abuse, which may affect the total dose of sedation. This hypothesis should be mentioned in the
discussion section.
3. The rate of intraoperative bleeding in this study appears to be higher than that reported
in the previous studies on esophageal ESD. As intraoperative bleeding and perforation also
may influence the decision of SDD following ESD, definition of these terms should be clearly
provided in the manuscript.
Minor
1. In the result section, the number of patients with early esophageal cancer who underwent ESD
was 168. However, in Figure1, the number of patients with early esophageal cancer was 168.
The sentence in the manuscript should be corrected.
Please review this paper.
user
Title: Feasibility and predictors of same-day discharge following endoscopic submucosal
dissection for early esophageal cancer
Version: 1 Date: 28 Apr 2025
Reviewer's report:
The authors presented a study on the feasibility and predictors of same-day discharge following
endoscopic submucosal dissection for early esophageal cancer.
This manuscript is well written and organized. However, this manuscript has few novelties.
Below are the comments and questions.
Major
1. This study focuses on the clinical characteristics to evaluate the feasibility and risk factors
of same-day discharge following esophageal ESD. However, to properly assess feasibility, the
post-discharge clinical course (e.g. symptoms, aspirated pneumonia, the presence of visiting
emergency care unit and readmission to the hospital) should also be discussed.
2. Since the type and dose of sedation used during ESD may influence discharge timing,
these details should be reported. In addition, from previous studies, alcohol abuse is correlated
with unsuccessful sedation. This suggests more sedation needs in the patients with alcohol
abuse, which may affect the total dose of sedation. This hypothesis should be mentioned in the
discussion section.
3. The rate of intraoperative bleeding in this study appears to be higher than that reported
in the previous studies on esophageal ESD. As intraoperative bleeding and perforation also
may influence the decision of SDD following ESD, definition of these terms should be clearly
provided in the manuscript.
Minor
1. In the result section, the number of patients with early esophageal cancer who underwent ESD
was 168. However, in Figure1, the number of patients with early esophageal cancer was 168.
The sentence in the manuscript should be corrected.
assistant