Reviewer's report
Title:Dose-dependent effects of lesogaberan on reflux measures in patients with
refractory gastroesophageal reflux disease: a randomized, placebo-controlled
study
Version:2Date:17 April 2014
Reviewer: Stanislas Bruley des Varannes
Reviewer's report:
This is a well conducted study addressing an interesting pharmacodynamic
question, though the development was discontinued.
The paper is well written, the methodology is suitable to the aims of the study
and described accurately. Data are presented and discussed clearly. In
addition, strengths and limitations of the study are honestly acknowledged.
illustrations are of quality
I have no major criticism to this study.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: Yes, but I do not feel adequately qualified to assess the
statistics.
Declaration of competing interests:
I declare that I have no competing interests
Reviewer's report
Title:Dose-dependent effects of lesogaberan on reflux measures in patients with
refractory gastroesophageal reflux disease: a randomized, placebo-controlled
study
Version:2Date:17 April 2014
Reviewer: Stanislas Bruley des Varannes
Reviewer's report:
This is a well conducted study addressing an interesting pharmacodynamic
question, though the development was discontinued.
The paper is well written, the methodology is suitable to the aims of the study
and described accurately. Data are presented and discussed clearly. In
addition, strengths and limitations of the study are honestly acknowledged.
illustrations are of quality
I have no major criticism to this study.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: Yes, but I do not feel adequately qualified to assess the
statistics.
Declaration of competing interests:
I declare that I have no competing interests
Please review this paper.
user
Reviewer's report
Title:Dose-dependent effects of lesogaberan on reflux measures in patients with
refractory gastroesophageal reflux disease: a randomized, placebo-controlled
study
Version:2Date:17 April 2014
Reviewer: Stanislas Bruley des Varannes
Reviewer's report:
This is a well conducted study addressing an interesting pharmacodynamic
question, though the development was discontinued.
The paper is well written, the methodology is suitable to the aims of the study
and described accurately. Data are presented and discussed clearly. In
addition, strengths and limitations of the study are honestly acknowledged.
illustrations are of quality
I have no major criticism to this study.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: Yes, but I do not feel adequately qualified to assess the
statistics.
Declaration of competing interests:
I declare that I have no competing interests
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