Title: Peptic ulcer characteristics in oral opium and non-opium user patients with upper
gastrointestinal bleeding
Version: 3 Date: 06 Dec 2023
Reviewer:  Panagiotis Tsibouris
Reviewer's report:
The text has been much improved  The figures included in the text from tables should be
followed be p values. In Table 2 apart from in total calculation of p values it should be useful
to calculate figures in each raw. Moreover erosive gastritis should be given separately from H.
pylori status, before the size of ulcers. Also H. pylori size is important to be given separately for
gastroduodenal ulcers were it is significant Authors should explain why they have not reseaved
biopsies from gastric ulcers At least they should include a comment in limitations It would be
interesting also to know if biopsies were available in esophageal ulcers to exclude viral infection
and allergic background.  Finally they should try to connect bibliographic references to their
findings For instant their comment on esophageal motility and GERD should be connected with
the increase in esophageal, mainly GEJ lessions
Title: Peptic ulcer characteristics in oral opium and non-opium user patients with upper
gastrointestinal bleeding
Version: 3 Date: 06 Dec 2023
Reviewer:  Panagiotis Tsibouris
Reviewer's report:
The text has been much improved  The figures included in the text from tables should be
followed be p values. In Table 2 apart from in total calculation of p values it should be useful
to calculate figures in each raw. Moreover erosive gastritis should be given separately from H.
pylori status, before the size of ulcers. Also H. pylori size is important to be given separately for
gastroduodenal ulcers were it is significant Authors should explain why they have not reseaved
biopsies from gastric ulcers At least they should include a comment in limitations It would be
interesting also to know if biopsies were available in esophageal ulcers to exclude viral infection
and allergic background.  Finally they should try to connect bibliographic references to their
findings For instant their comment on esophageal motility and GERD should be connected with
the increase in esophageal, mainly GEJ lessions
Please review this paper.
user
Title: Peptic ulcer characteristics in oral opium and non-opium user patients with upper
gastrointestinal bleeding
Version: 3 Date: 06 Dec 2023
Reviewer:  Panagiotis Tsibouris
Reviewer's report:
The text has been much improved  The figures included in the text from tables should be
followed be p values. In Table 2 apart from in total calculation of p values it should be useful
to calculate figures in each raw. Moreover erosive gastritis should be given separately from H.
pylori status, before the size of ulcers. Also H. pylori size is important to be given separately for
gastroduodenal ulcers were it is significant Authors should explain why they have not reseaved
biopsies from gastric ulcers At least they should include a comment in limitations It would be
interesting also to know if biopsies were available in esophageal ulcers to exclude viral infection
and allergic background.  Finally they should try to connect bibliographic references to their
findings For instant their comment on esophageal motility and GERD should be connected with
the increase in esophageal, mainly GEJ lessions
assistant