Title: The Efficacy of Retrograde and Antegrade Enemas in the Management of Low Anterior
Resection Syndrome in Patients Undergoing Rectal Resection: A Systematic Review and Meta-
analysis
Version: 2 Date: 23 Apr 2025
Reviewer's report:
The authors have appropriately addressed my previous comment regarding the limitations of the
study. This, in conjunction with the revisions made in response to the other reviewers and the
editorial team, has notably strengthened the manuscript. Upon further consideration, I believe
this systematic review and meta-analysis is now suitable for acceptance.
Title: The Efficacy of Retrograde and Antegrade Enemas in the Management of Low Anterior
Resection Syndrome in Patients Undergoing Rectal Resection: A Systematic Review and Meta-
analysis
Version: 2 Date: 23 Apr 2025
Reviewer's report:
The authors have appropriately addressed my previous comment regarding the limitations of the
study. This, in conjunction with the revisions made in response to the other reviewers and the
editorial team, has notably strengthened the manuscript. Upon further consideration, I believe
this systematic review and meta-analysis is now suitable for acceptance.
Please review this paper.
user
Title: The Efficacy of Retrograde and Antegrade Enemas in the Management of Low Anterior
Resection Syndrome in Patients Undergoing Rectal Resection: A Systematic Review and Meta-
analysis
Version: 2 Date: 23 Apr 2025
Reviewer's report:
The authors have appropriately addressed my previous comment regarding the limitations of the
study. This, in conjunction with the revisions made in response to the other reviewers and the
editorial team, has notably strengthened the manuscript. Upon further consideration, I believe
this systematic review and meta-analysis is now suitable for acceptance.
assistant