Title: Risk factors of additional surgery after non-curative endoscopic submucosal dissection
for early gastric cancer
Version: 1 Date: 03 Sep 2023
Reviewer's report:
This is a retrospective study on the risk for recurrence and lymph node metastasis after non-
curative ESD of early gastric cancer. The authors found that 78.2% of patients with incomplete
ESD who underwent additional surgery had no residual disease and no lymph node metastasis.
Independent risk factor for recurrence/residual cancer was a positive horizontal margin and
lymphatic infiltration was an independent risk factor for lymph node metastasis.
I have the following comments:
The authors should mention in the abstract that they were dealing with ESD of early gastric
cancer. This was mentioned in the title only.
The authors should provide a table explaining the different curable resection grades mentioned
in the introduction. The general reader won’t be aware of this grading.
How many patients without one of the mentioned risk factors had residual cancer or lymph node
metastasis?
Can you provide post-surgical follow-up? Did patients experience recurrence after surgery? How
many patients died from gastric cancer?
Title: Risk factors of additional surgery after non-curative endoscopic submucosal dissection
for early gastric cancer
Version: 1 Date: 03 Sep 2023
Reviewer's report:
This is a retrospective study on the risk for recurrence and lymph node metastasis after non-
curative ESD of early gastric cancer. The authors found that 78.2% of patients with incomplete
ESD who underwent additional surgery had no residual disease and no lymph node metastasis.
Independent risk factor for recurrence/residual cancer was a positive horizontal margin and
lymphatic infiltration was an independent risk factor for lymph node metastasis.
I have the following comments:
The authors should mention in the abstract that they were dealing with ESD of early gastric
cancer. This was mentioned in the title only.
The authors should provide a table explaining the different curable resection grades mentioned
in the introduction. The general reader won’t be aware of this grading.
How many patients without one of the mentioned risk factors had residual cancer or lymph node
metastasis?
Can you provide post-surgical follow-up? Did patients experience recurrence after surgery? How
many patients died from gastric cancer?
Please review this paper.
user
Title: Risk factors of additional surgery after non-curative endoscopic submucosal dissection
for early gastric cancer
Version: 1 Date: 03 Sep 2023
Reviewer's report:
This is a retrospective study on the risk for recurrence and lymph node metastasis after non-
curative ESD of early gastric cancer. The authors found that 78.2% of patients with incomplete
ESD who underwent additional surgery had no residual disease and no lymph node metastasis.
Independent risk factor for recurrence/residual cancer was a positive horizontal margin and
lymphatic infiltration was an independent risk factor for lymph node metastasis.
I have the following comments:
The authors should mention in the abstract that they were dealing with ESD of early gastric
cancer. This was mentioned in the title only.
The authors should provide a table explaining the different curable resection grades mentioned
in the introduction. The general reader won’t be aware of this grading.
How many patients without one of the mentioned risk factors had residual cancer or lymph node
metastasis?
Can you provide post-surgical follow-up? Did patients experience recurrence after surgery? How
many patients died from gastric cancer?
assistant