Reviewer ’s report  
Title : A case of IgG4 -related hepatic inflammatory pseudotumor replaced by an abscess af ter 
steroid treatment  
 
Version:  0 Date : 08 Apr 2016  
 
Reviewer : Chhagan Bihari  
 
Reviewer's report:  
Author Described a case of IgG4 related inflammatory tumor in liver,  
1. The entity is now not very rare or surprising. It is a well established fact that IgG4 related 
disease can present as mass  lesion and these are antibiotic and steroid responsive.  
2. Second point author highlight that these entity mimic with malignancy and histopathological 
diagnosis is required, that is also very well established fact.  
3. Authors mentioned that patient underw ent pancreatico -duodenectomy for Hilar 
cholangiocarcinoma, this is beyond the understanding, since authors have not mentioned 
whether there was partial hepatectomy done or not.  
4. And it is surprising that authors have not mentioned the Pathological and cl inical staging of 
previous tumor.  
5. If patient was having Hilar Cholangiocarcinoma, then how author's will describe the good 
tumor reponse and patient's excellent survival.  
 
Are the methods appropriate and well described?  
If not, please specify what is req uired in your comments to the authors.  
No 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
No 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explai n in your comments to the authors.  
No 
Are you able to assess any statistics in the manuscript or would you recommend an 
additional statistical review?  
If an additional statistical review is recommended, please specify what aspects require further 
assessment i n your comments to the editors.  
Not relevant to this manuscript  
Quality of written English  
Please indicate the quality of language in the manuscript:  
Acceptable  
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following questions:  
1. Have you in the past five years r eceived reimbursements, f ees, funding, or salary from an 
organisation that may in any way gain or lose financial ly from the publication of this 
manuscript, either now or in the future?  
2. Do you hold any stocks or shares in an organisation t hat may in any way gain or lose 
financially from the publication of this manuscript, either now or in the future?  
3. Do you hold or are you currently applying for any patents relating to the content o f the 
manuscript?  
4. Have you received reimbursements, fees, funding, or salary from an organization that 
holds or has applied for patents relating to the content of the manuscript?  
5. Do you have any other financial competing interests?  
6. Do you have any  non-financial competing interests in relation to this paper?  
If you can answer no to all of the above, write 'I declare that I have no competing interests' 
below . If your reply is yes to any, please give details below.  
I declare that I have no competing interests'  
I agree to the open peer review policy of the journal. I understand that my name will be included 
on my report to the authors and, if the manuscript is a ccepted for publication, my named report 
including any attachments I upload will be posted on the website along with the authors' 
responses. I agree for my report to be made available under an Open Access Creative Commons 
CC-BY license ( http://creativecomm ons.org/licenses/by/4.0/ ). I understand that any comments 
which I do not wish to be included in my named report can be included as confidential comments 
to the editors, which will not be published.  
I agree to the open peer review policy of the journal  
Reviewer ’s report  
Title : A case of IgG4 -related hepatic inflammatory pseudotumor replaced by an abscess af ter 
steroid treatment  
 
Version:  0 Date : 08 Apr 2016  
 
Reviewer : Chhagan Bihari  
 
Reviewer's report:  
Author Described a case of IgG4 related inflammatory tumor in liver,  
1. The entity is now not very rare or surprising. It is a well established fact that IgG4 related 
disease can present as mass  lesion and these are antibiotic and steroid responsive.  
2. Second point author highlight that these entity mimic with malignancy and histopathological 
diagnosis is required, that is also very well established fact.  
3. Authors mentioned that patient underw ent pancreatico -duodenectomy for Hilar 
cholangiocarcinoma, this is beyond the understanding, since authors have not mentioned 
whether there was partial hepatectomy done or not.  
4. And it is surprising that authors have not mentioned the Pathological and cl inical staging of 
previous tumor.  
5. If patient was having Hilar Cholangiocarcinoma, then how author's will describe the good 
tumor reponse and patient's excellent survival.  
 
Are the methods appropriate and well described?  
If not, please specify what is req uired in your comments to the authors.  
No 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
No 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explai n in your comments to the authors.  
No 
Are you able to assess any statistics in the manuscript or would you recommend an 
additional statistical review?  
If an additional statistical review is recommended, please specify what aspects require further 
assessment i n your comments to the editors.  
Not relevant to this manuscript  
Quality of written English  
Please indicate the quality of language in the manuscript:  
Acceptable  
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following questions:  
1. Have you in the past five years r eceived reimbursements, f ees, funding, or salary from an 
organisation that may in any way gain or lose financial ly from the publication of this 
manuscript, either now or in the future?  
2. Do you hold any stocks or shares in an organisation t hat may in any way gain or lose 
financially from the publication of this manuscript, either now or in the future?  
3. Do you hold or are you currently applying for any patents relating to the content o f the 
manuscript?  
4. Have you received reimbursements, fees, funding, or salary from an organization that 
holds or has applied for patents relating to the content of the manuscript?  
5. Do you have any other financial competing interests?  
6. Do you have any  non-financial competing interests in relation to this paper?  
If you can answer no to all of the above, write 'I declare that I have no competing interests' 
below . If your reply is yes to any, please give details below.  
I declare that I have no competing interests'  
I agree to the open peer review policy of the journal. I understand that my name will be included 
on my report to the authors and, if the manuscript is a ccepted for publication, my named report 
including any attachments I upload will be posted on the website along with the authors' 
responses. I agree for my report to be made available under an Open Access Creative Commons 
CC-BY license ( http://creativecomm ons.org/licenses/by/4.0/ ). I understand that any comments 
which I do not wish to be included in my named report can be included as confidential comments 
to the editors, which will not be published.  
I agree to the open peer review policy of the journal  
Please review this paper.
user
Reviewer ’s report  
Title : A case of IgG4 -related hepatic inflammatory pseudotumor replaced by an abscess af ter 
steroid treatment  
 
Version:  0 Date : 08 Apr 2016  
 
Reviewer : Chhagan Bihari  
 
Reviewer's report:  
Author Described a case of IgG4 related inflammatory tumor in liver,  
1. The entity is now not very rare or surprising. It is a well established fact that IgG4 related 
disease can present as mass  lesion and these are antibiotic and steroid responsive.  
2. Second point author highlight that these entity mimic with malignancy and histopathological 
diagnosis is required, that is also very well established fact.  
3. Authors mentioned that patient underw ent pancreatico -duodenectomy for Hilar 
cholangiocarcinoma, this is beyond the understanding, since authors have not mentioned 
whether there was partial hepatectomy done or not.  
4. And it is surprising that authors have not mentioned the Pathological and cl inical staging of 
previous tumor.  
5. If patient was having Hilar Cholangiocarcinoma, then how author's will describe the good 
tumor reponse and patient's excellent survival.  
 
Are the methods appropriate and well described?  
If not, please specify what is req uired in your comments to the authors.  
No 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
No 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explai n in your comments to the authors.  
No 
Are you able to assess any statistics in the manuscript or would you recommend an 
additional statistical review?  
If an additional statistical review is recommended, please specify what aspects require further 
assessment i n your comments to the editors.  
Not relevant to this manuscript  
Quality of written English  
Please indicate the quality of language in the manuscript:  
Acceptable  
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following questions:  
1. Have you in the past five years r eceived reimbursements, f ees, funding, or salary from an 
organisation that may in any way gain or lose financial ly from the publication of this 
manuscript, either now or in the future?  
2. Do you hold any stocks or shares in an organisation t hat may in any way gain or lose 
financially from the publication of this manuscript, either now or in the future?  
3. Do you hold or are you currently applying for any patents relating to the content o f the 
manuscript?  
4. Have you received reimbursements, fees, funding, or salary from an organization that 
holds or has applied for patents relating to the content of the manuscript?  
5. Do you have any other financial competing interests?  
6. Do you have any  non-financial competing interests in relation to this paper?  
If you can answer no to all of the above, write 'I declare that I have no competing interests' 
below . If your reply is yes to any, please give details below.  
I declare that I have no competing interests'  
I agree to the open peer review policy of the journal. I understand that my name will be included 
on my report to the authors and, if the manuscript is a ccepted for publication, my named report 
including any attachments I upload will be posted on the website along with the authors' 
responses. I agree for my report to be made available under an Open Access Creative Commons 
CC-BY license ( http://creativecomm ons.org/licenses/by/4.0/ ). I understand that any comments 
which I do not wish to be included in my named report can be included as confidential comments 
to the editors, which will not be published.  
I agree to the open peer review policy of the journal  
assistant