Title: The Effect of Solid Food Diet Therapies on the Induction and Maintenance of Remission
in Crohn’s Disease: A Systematic Review
Version: 1 Date: 13 May 2024
Reviewer:  Sarah M Ajabnoor
Reviewer's report:
This systematic review of different RCTs aimed to assess the effect of different solid diet
therapies on the induction and maintenance of remission in patients with Crohn’s disease. A total
of 14 trials were included in the systematic review. The authors concluded that some available
diet therapies may have positive outcomes, but the evidence is still limited due to the lack of
robust high-quality trials.
The focus of this systematic review provides interesting findings, which will help in directing
future research concerned with dietary management in IBD. However, the manuscript and the
review summary tables need some adjustments. Please see the comments below.
To author:
- Title: The word (maintenance) is missing from the title. The title should be like (The Effect of
Solid Food Diet Therapies on the Induction and Maintenance of Remission in Crohn’s Disease:
…………..…..etc.)
- Methods: Search strategy: the author needs to specify the selected time frame (years) for
included studies. Did the author exclude any study before a specific time frame? Need to be
stated.
- Methods: Critical appraisal: The author needs to provide the citation for the quality assessment
tool.
- Results: The Summary tables are crowded and not clear. It needs some modification for better
illustartation of studies’ findings. The author needs to tabulate the extracted data from the studies
in a better way (i.e., more informative and summarized). E.g., the following information can
be presented in a separate column: study sample size, participant age, duration of intervention,
Results of disease activity index/remission rate, results of inflammatory markers, results of gut
symptoms, and quality of life.
- Results: Line 249: there is a spelling mistake. Need to remove one (no) for the sentence.
- Discussion: Line 453 – 455: The textual results concerning the quality of included studies
need to be mentioned in the Results section of the systematic review and not in the discussion.
I suggest adding a paragraph in the results to better explain the results for Figure 2.
- Overall, the manuscript is good But needs to be proofread.
Title: The Effect of Solid Food Diet Therapies on the Induction and Maintenance of Remission
in Crohn’s Disease: A Systematic Review
Version: 1 Date: 13 May 2024
Reviewer:  Sarah M Ajabnoor
Reviewer's report:
This systematic review of different RCTs aimed to assess the effect of different solid diet
therapies on the induction and maintenance of remission in patients with Crohn’s disease. A total
of 14 trials were included in the systematic review. The authors concluded that some available
diet therapies may have positive outcomes, but the evidence is still limited due to the lack of
robust high-quality trials.
The focus of this systematic review provides interesting findings, which will help in directing
future research concerned with dietary management in IBD. However, the manuscript and the
review summary tables need some adjustments. Please see the comments below.
To author:
- Title: The word (maintenance) is missing from the title. The title should be like (The Effect of
Solid Food Diet Therapies on the Induction and Maintenance of Remission in Crohn’s Disease:
…………..…..etc.)
- Methods: Search strategy: the author needs to specify the selected time frame (years) for
included studies. Did the author exclude any study before a specific time frame? Need to be
stated.
- Methods: Critical appraisal: The author needs to provide the citation for the quality assessment
tool.
- Results: The Summary tables are crowded and not clear. It needs some modification for better
illustartation of studies’ findings. The author needs to tabulate the extracted data from the studies
in a better way (i.e., more informative and summarized). E.g., the following information can
be presented in a separate column: study sample size, participant age, duration of intervention,
Results of disease activity index/remission rate, results of inflammatory markers, results of gut
symptoms, and quality of life.
- Results: Line 249: there is a spelling mistake. Need to remove one (no) for the sentence.
- Discussion: Line 453 – 455: The textual results concerning the quality of included studies
need to be mentioned in the Results section of the systematic review and not in the discussion.
I suggest adding a paragraph in the results to better explain the results for Figure 2.
- Overall, the manuscript is good But needs to be proofread.
Please review this paper.
user
Title: The Effect of Solid Food Diet Therapies on the Induction and Maintenance of Remission
in Crohn’s Disease: A Systematic Review
Version: 1 Date: 13 May 2024
Reviewer:  Sarah M Ajabnoor
Reviewer's report:
This systematic review of different RCTs aimed to assess the effect of different solid diet
therapies on the induction and maintenance of remission in patients with Crohn’s disease. A total
of 14 trials were included in the systematic review. The authors concluded that some available
diet therapies may have positive outcomes, but the evidence is still limited due to the lack of
robust high-quality trials.
The focus of this systematic review provides interesting findings, which will help in directing
future research concerned with dietary management in IBD. However, the manuscript and the
review summary tables need some adjustments. Please see the comments below.
To author:
- Title: The word (maintenance) is missing from the title. The title should be like (The Effect of
Solid Food Diet Therapies on the Induction and Maintenance of Remission in Crohn’s Disease:
…………..…..etc.)
- Methods: Search strategy: the author needs to specify the selected time frame (years) for
included studies. Did the author exclude any study before a specific time frame? Need to be
stated.
- Methods: Critical appraisal: The author needs to provide the citation for the quality assessment
tool.
- Results: The Summary tables are crowded and not clear. It needs some modification for better
illustartation of studies’ findings. The author needs to tabulate the extracted data from the studies
in a better way (i.e., more informative and summarized). E.g., the following information can
be presented in a separate column: study sample size, participant age, duration of intervention,
Results of disease activity index/remission rate, results of inflammatory markers, results of gut
symptoms, and quality of life.
- Results: Line 249: there is a spelling mistake. Need to remove one (no) for the sentence.
- Discussion: Line 453 – 455: The textual results concerning the quality of included studies
need to be mentioned in the Results section of the systematic review and not in the discussion.
I suggest adding a paragraph in the results to better explain the results for Figure 2.
- Overall, the manuscript is good But needs to be proofread.
assistant