Title: Association between cumulative uric acid exposure and metabolic dysfunction-associated
fatty liver disease
Version: 1 Date: 10 Feb 2025
Reviewer's report:
This manuscript is interesting and used very huge data to analyse relationship  UA cumulative
exposure to incidence of MAFLD, but unfortunately the author did not explain in backgrounds
clearly about the patogenesis and why we should aware or concern about this relationship.
Please make the additional with the simple explanation to become the novelty of study.
Please revision the language and written especially in abstracts.
Please make the conclusion in abstract and manuscript similar , and included of all of the results.
Some results in contrary with previous study such as abdominal obesity and physical
examination, please check again why this happen, it is because of the wrong statistical analysis ,
or because of data imbalance such as the total subjects of male very different with woman.
there is so many statistical issue but if we looked at the results ,it is almost the same results.
could you make it more simple .
Title: Association between cumulative uric acid exposure and metabolic dysfunction-associated
fatty liver disease
Version: 1 Date: 10 Feb 2025
Reviewer's report:
This manuscript is interesting and used very huge data to analyse relationship  UA cumulative
exposure to incidence of MAFLD, but unfortunately the author did not explain in backgrounds
clearly about the patogenesis and why we should aware or concern about this relationship.
Please make the additional with the simple explanation to become the novelty of study.
Please revision the language and written especially in abstracts.
Please make the conclusion in abstract and manuscript similar , and included of all of the results.
Some results in contrary with previous study such as abdominal obesity and physical
examination, please check again why this happen, it is because of the wrong statistical analysis ,
or because of data imbalance such as the total subjects of male very different with woman.
there is so many statistical issue but if we looked at the results ,it is almost the same results.
could you make it more simple .
Please review this paper.
user
Title: Association between cumulative uric acid exposure and metabolic dysfunction-associated
fatty liver disease
Version: 1 Date: 10 Feb 2025
Reviewer's report:
This manuscript is interesting and used very huge data to analyse relationship  UA cumulative
exposure to incidence of MAFLD, but unfortunately the author did not explain in backgrounds
clearly about the patogenesis and why we should aware or concern about this relationship.
Please make the additional with the simple explanation to become the novelty of study.
Please revision the language and written especially in abstracts.
Please make the conclusion in abstract and manuscript similar , and included of all of the results.
Some results in contrary with previous study such as abdominal obesity and physical
examination, please check again why this happen, it is because of the wrong statistical analysis ,
or because of data imbalance such as the total subjects of male very different with woman.
there is so many statistical issue but if we looked at the results ,it is almost the same results.
could you make it more simple .
assistant