Title: The longterm impact of post-cholecystectomy major bile duct injury on liver stiffness.
Version: 3 Date: 26 Jul 2024
Reviewer's report:
I appreciate the opportunity to review this interesting article. In the paper, the authors provide
a thorough examination of the long-term impact of hepaticojejunostomy on liver stiffness and
fibrosis. They conclude that while major bile duct injury (BDI) repair using hepaticojejunostomy
does not show a significant difference in overall liver fibrosis compared to controls, the presence
of right hepatic artery injury or anastomotic stricture may increase the risk of significant fibrosis.
Bile duct injury, which is difficult to completely eliminate, is a serious complication in biliary
surgeries such as cholecystectomy. Moreover, managing biliary injury is complex and requires
careful, individualized planning and coordination to address both the immediate surgical needs
and the long-term implications for patient health.
Although the theme is interesting, aspects of the study design, such as the study population,
inclusion criteria, and methods of comparison, are not well described, making it difficult to
clearly understand the focus of the study. These are fundamental aspects of the research. Unless
they are clarified, it may be difficult to publish the article.
Title: The longterm impact of post-cholecystectomy major bile duct injury on liver stiffness.
Version: 3 Date: 26 Jul 2024
Reviewer's report:
I appreciate the opportunity to review this interesting article. In the paper, the authors provide
a thorough examination of the long-term impact of hepaticojejunostomy on liver stiffness and
fibrosis. They conclude that while major bile duct injury (BDI) repair using hepaticojejunostomy
does not show a significant difference in overall liver fibrosis compared to controls, the presence
of right hepatic artery injury or anastomotic stricture may increase the risk of significant fibrosis.
Bile duct injury, which is difficult to completely eliminate, is a serious complication in biliary
surgeries such as cholecystectomy. Moreover, managing biliary injury is complex and requires
careful, individualized planning and coordination to address both the immediate surgical needs
and the long-term implications for patient health.
Although the theme is interesting, aspects of the study design, such as the study population,
inclusion criteria, and methods of comparison, are not well described, making it difficult to
clearly understand the focus of the study. These are fundamental aspects of the research. Unless
they are clarified, it may be difficult to publish the article.
Please review this paper.
user
Title: The longterm impact of post-cholecystectomy major bile duct injury on liver stiffness.
Version: 3 Date: 26 Jul 2024
Reviewer's report:
I appreciate the opportunity to review this interesting article. In the paper, the authors provide
a thorough examination of the long-term impact of hepaticojejunostomy on liver stiffness and
fibrosis. They conclude that while major bile duct injury (BDI) repair using hepaticojejunostomy
does not show a significant difference in overall liver fibrosis compared to controls, the presence
of right hepatic artery injury or anastomotic stricture may increase the risk of significant fibrosis.
Bile duct injury, which is difficult to completely eliminate, is a serious complication in biliary
surgeries such as cholecystectomy. Moreover, managing biliary injury is complex and requires
careful, individualized planning and coordination to address both the immediate surgical needs
and the long-term implications for patient health.
Although the theme is interesting, aspects of the study design, such as the study population,
inclusion criteria, and methods of comparison, are not well described, making it difficult to
clearly understand the focus of the study. These are fundamental aspects of the research. Unless
they are clarified, it may be difficult to publish the article.
assistant