Title: AST/ALT ratio, APRI, and FIB-4 compared to FibroScan for the assessment of liver
fibrosis in patients with chronic hepatitis B in Bandar Abbas, Hormozgan, Iran
Version: 0 Date: 02 Mar 2023
Reviewer:  Pathik Parikh
Reviewer's report:
Fibroscan has limitations with Obesity.
1. It would be worthwhile looking at the correlation of fibroscan with these variables with and
without obesity
2. Fibroscan inter-observer variations
3. If histopathology is available for any of these patients, adding data on these would be
worthwhile
4. FIB Plus if feasible being a recent score should also be considered
5. Corelating hepatitis B activity - infection or disease; eAg positive and negative for the amount
of fibrosis if available can be included
Title: AST/ALT ratio, APRI, and FIB-4 compared to FibroScan for the assessment of liver
fibrosis in patients with chronic hepatitis B in Bandar Abbas, Hormozgan, Iran
Version: 0 Date: 02 Mar 2023
Reviewer:  Pathik Parikh
Reviewer's report:
Fibroscan has limitations with Obesity.
1. It would be worthwhile looking at the correlation of fibroscan with these variables with and
without obesity
2. Fibroscan inter-observer variations
3. If histopathology is available for any of these patients, adding data on these would be
worthwhile
4. FIB Plus if feasible being a recent score should also be considered
5. Corelating hepatitis B activity - infection or disease; eAg positive and negative for the amount
of fibrosis if available can be included
Please review this paper.
user
Title: AST/ALT ratio, APRI, and FIB-4 compared to FibroScan for the assessment of liver
fibrosis in patients with chronic hepatitis B in Bandar Abbas, Hormozgan, Iran
Version: 0 Date: 02 Mar 2023
Reviewer:  Pathik Parikh
Reviewer's report:
Fibroscan has limitations with Obesity.
1. It would be worthwhile looking at the correlation of fibroscan with these variables with and
without obesity
2. Fibroscan inter-observer variations
3. If histopathology is available for any of these patients, adding data on these would be
worthwhile
4. FIB Plus if feasible being a recent score should also be considered
5. Corelating hepatitis B activity - infection or disease; eAg positive and negative for the amount
of fibrosis if available can be included
assistant