Title: Washed microbiota transplantation improves symptoms and intestinal barrier function in
patients with functional bowel disorders: A propensity-score matching analysis
Version: 0 Date: 14 Nov 2023
Reviewer's report:
The topic of this manuscript si always interesting.
However, the writing has several issues to be explained and addressed:
- why using Functional GI disorders nomenclature and not DGBI ?
- what are the bias of the retrospective and, most of all, of propensity analysis ? matcheing perfect
pairs has several drawbacks. This has deeply conditioned the harmony of results.
- D-lactate prognostic value is not so strong, and ahas been calculated at univariate analysis.
This is an important bias, also.
- The numbers of patients enrolled are little;
- English revision is needed.
- Figures and tables are OK but Methodology arises several concerns.
Title: Washed microbiota transplantation improves symptoms and intestinal barrier function in
patients with functional bowel disorders: A propensity-score matching analysis
Version: 0 Date: 14 Nov 2023
Reviewer's report:
The topic of this manuscript si always interesting.
However, the writing has several issues to be explained and addressed:
- why using Functional GI disorders nomenclature and not DGBI ?
- what are the bias of the retrospective and, most of all, of propensity analysis ? matcheing perfect
pairs has several drawbacks. This has deeply conditioned the harmony of results.
- D-lactate prognostic value is not so strong, and ahas been calculated at univariate analysis.
This is an important bias, also.
- The numbers of patients enrolled are little;
- English revision is needed.
- Figures and tables are OK but Methodology arises several concerns.
Please review this paper.
user
Title: Washed microbiota transplantation improves symptoms and intestinal barrier function in
patients with functional bowel disorders: A propensity-score matching analysis
Version: 0 Date: 14 Nov 2023
Reviewer's report:
The topic of this manuscript si always interesting.
However, the writing has several issues to be explained and addressed:
- why using Functional GI disorders nomenclature and not DGBI ?
- what are the bias of the retrospective and, most of all, of propensity analysis ? matcheing perfect
pairs has several drawbacks. This has deeply conditioned the harmony of results.
- D-lactate prognostic value is not so strong, and ahas been calculated at univariate analysis.
This is an important bias, also.
- The numbers of patients enrolled are little;
- English revision is needed.
- Figures and tables are OK but Methodology arises several concerns.
assistant