Reviewer's report
Title:An association between colonic adenoma and abdominal obesity : A cross
sectional study.
Version: 5Date:5 December 2008
Reviewer: patricia thompson
Reviewer's report:
In the revised manuscript YoungJoo Kim et al., have been highly responsive to
the previous reviewer comments, attempting to address issues that were raised
by each of the three previous reviewers. The readability of the manuscript is
greatly improved.
Minor Essential Revisions
There remain minor but not insignificant issues with word choice, grammar and
sentence structure that could use further attention.
Examples:
Discussion, first sentence, second paragraph “Many studies have been
concluded on the association”… should be changed to Many studies have been
conducted on the association …
Discussion, second paragraph
However studies conducted on central obesity as a risk factor of colon adenoma,
‘has’ should be changed to have been limited and the association remains
controversial.
Other minor issues that need to be addressed:
Discussion sentence stating that “BMI was not significantly associated with
adenoma after adjusting for waist circumference, which concurs with the findings
of previous studies” - needs referencing.
Discretionary Revisions
Because waist is so strongly associated with risk in this study of an Asian study
population, it would be of high value for the discussion to include one concise
paragraph about differences in the relative importance of specific body
composition measures in different populations. In general, BMI and waist
circumference are highly correlated in Caucasian populations and thus,
adjustment of one for the other often attenuates the effect. Here, waist after
adjusting for BMI is presenting as a very strong risk factor for colorectal
adenoma. It would be of interest to discuss the relationship between metabolic
syndrome and waist circumference versus BMI measures in an Asian population.
In the absence of an opportunity to directly measure the relationship between
metabolic syndrome and risk, a thoughtful discussion of the relationship with
waist versus BMI in the Asian population would be useful to a reader and raise
the overall impact of the manuscript.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
'I declare that I have no competing interests'
Reviewer's report
Title:An association between colonic adenoma and abdominal obesity : A cross
sectional study.
Version: 5Date:5 December 2008
Reviewer: patricia thompson
Reviewer's report:
In the revised manuscript YoungJoo Kim et al., have been highly responsive to
the previous reviewer comments, attempting to address issues that were raised
by each of the three previous reviewers. The readability of the manuscript is
greatly improved.
Minor Essential Revisions
There remain minor but not insignificant issues with word choice, grammar and
sentence structure that could use further attention.
Examples:
Discussion, first sentence, second paragraph “Many studies have been
concluded on the association”… should be changed to Many studies have been
conducted on the association …
Discussion, second paragraph
However studies conducted on central obesity as a risk factor of colon adenoma,
‘has’ should be changed to have been limited and the association remains
controversial.
Other minor issues that need to be addressed:
Discussion sentence stating that “BMI was not significantly associated with
adenoma after adjusting for waist circumference, which concurs with the findings
of previous studies” - needs referencing.
Discretionary Revisions
Because waist is so strongly associated with risk in this study of an Asian study
population, it would be of high value for the discussion to include one concise
paragraph about differences in the relative importance of specific body
composition measures in different populations. In general, BMI and waist
circumference are highly correlated in Caucasian populations and thus,
adjustment of one for the other often attenuates the effect. Here, waist after
adjusting for BMI is presenting as a very strong risk factor for colorectal
adenoma. It would be of interest to discuss the relationship between metabolic
syndrome and waist circumference versus BMI measures in an Asian population.
In the absence of an opportunity to directly measure the relationship between
metabolic syndrome and risk, a thoughtful discussion of the relationship with
waist versus BMI in the Asian population would be useful to a reader and raise
the overall impact of the manuscript.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
'I declare that I have no competing interests'
Please review this paper.
user
Reviewer's report
Title:An association between colonic adenoma and abdominal obesity : A cross
sectional study.
Version: 5Date:5 December 2008
Reviewer: patricia thompson
Reviewer's report:
In the revised manuscript YoungJoo Kim et al., have been highly responsive to
the previous reviewer comments, attempting to address issues that were raised
by each of the three previous reviewers. The readability of the manuscript is
greatly improved.
Minor Essential Revisions
There remain minor but not insignificant issues with word choice, grammar and
sentence structure that could use further attention.
Examples:
Discussion, first sentence, second paragraph “Many studies have been
concluded on the association”… should be changed to Many studies have been
conducted on the association …
Discussion, second paragraph
However studies conducted on central obesity as a risk factor of colon adenoma,
‘has’ should be changed to have been limited and the association remains
controversial.
Other minor issues that need to be addressed:
Discussion sentence stating that “BMI was not significantly associated with
adenoma after adjusting for waist circumference, which concurs with the findings
of previous studies” - needs referencing.
Discretionary Revisions
Because waist is so strongly associated with risk in this study of an Asian study
population, it would be of high value for the discussion to include one concise
paragraph about differences in the relative importance of specific body
composition measures in different populations. In general, BMI and waist
circumference are highly correlated in Caucasian populations and thus,
adjustment of one for the other often attenuates the effect. Here, waist after
adjusting for BMI is presenting as a very strong risk factor for colorectal
adenoma. It would be of interest to discuss the relationship between metabolic
syndrome and waist circumference versus BMI measures in an Asian population.
In the absence of an opportunity to directly measure the relationship between
metabolic syndrome and risk, a thoughtful discussion of the relationship with
waist versus BMI in the Asian population would be useful to a reader and raise
the overall impact of the manuscript.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
'I declare that I have no competing interests'
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