Title: DEVELOPMENT AND VALIDATION OF A VIDEO-ASSISTED LIVER BIOPSY
TECHNIQUE USING A MINIMALLY-INVASIVE DEVICE
Version: 3 Date: 19 Oct 2022
Reviewer's report:
Authors developed a video-assisted technique that uses only a minimally-invasive device for the
liver biopsy and the optical trocar.  Without additional trocars, this technique constitutes a less
invasive procedure than the existing techniques in clinical practice.
I think this is an interesting article. But I have several questions as follow.
1. The sample size in this paper is too small, which may cause statistical errors. If possible,
please increase the sample size appropriately.
2.Laparoscopic biopsy can be performed at the same time as biopsy, exploration, resection and
other operations, but the new biopsy method in this paper can not complete the above operations.
Otherwise#this method is difficult to biopsy lesions on the visceral surface of the liver. So the
indications and suitable population of the new method need to be further discussed.
3.In addition, traditional percutaneous liver biopsy can be performed under local anesthesia.
This method requires general anesthesia, so its clinical utility is explained in the discussion.
Title: DEVELOPMENT AND VALIDATION OF A VIDEO-ASSISTED LIVER BIOPSY
TECHNIQUE USING A MINIMALLY-INVASIVE DEVICE
Version: 3 Date: 19 Oct 2022
Reviewer's report:
Authors developed a video-assisted technique that uses only a minimally-invasive device for the
liver biopsy and the optical trocar.  Without additional trocars, this technique constitutes a less
invasive procedure than the existing techniques in clinical practice.
I think this is an interesting article. But I have several questions as follow.
1. The sample size in this paper is too small, which may cause statistical errors. If possible,
please increase the sample size appropriately.
2.Laparoscopic biopsy can be performed at the same time as biopsy, exploration, resection and
other operations, but the new biopsy method in this paper can not complete the above operations.
Otherwise#this method is difficult to biopsy lesions on the visceral surface of the liver. So the
indications and suitable population of the new method need to be further discussed.
3.In addition, traditional percutaneous liver biopsy can be performed under local anesthesia.
This method requires general anesthesia, so its clinical utility is explained in the discussion.
Please review this paper.
user
Title: DEVELOPMENT AND VALIDATION OF A VIDEO-ASSISTED LIVER BIOPSY
TECHNIQUE USING A MINIMALLY-INVASIVE DEVICE
Version: 3 Date: 19 Oct 2022
Reviewer's report:
Authors developed a video-assisted technique that uses only a minimally-invasive device for the
liver biopsy and the optical trocar.  Without additional trocars, this technique constitutes a less
invasive procedure than the existing techniques in clinical practice.
I think this is an interesting article. But I have several questions as follow.
1. The sample size in this paper is too small, which may cause statistical errors. If possible,
please increase the sample size appropriately.
2.Laparoscopic biopsy can be performed at the same time as biopsy, exploration, resection and
other operations, but the new biopsy method in this paper can not complete the above operations.
Otherwise#this method is difficult to biopsy lesions on the visceral surface of the liver. So the
indications and suitable population of the new method need to be further discussed.
3.In addition, traditional percutaneous liver biopsy can be performed under local anesthesia.
This method requires general anesthesia, so its clinical utility is explained in the discussion.
assistant