Title: High neutrophil-lymphocyte ratio indicates a worse response to ursodeoxycholic acid in
primary biliary cholangitis: a retrospective cohort study
Version: 2 Date: 06 Oct 2023
Reviewer's report:
In the present manuscript, the authors analyzed how the neutrophil-to lymphocyte ratio might
change depending on the UDCA treatment in PBC patients. The great value of this research is
the large number of patients.
The research described and the conclusions drawn are a good starting point for further analyses
(especially cell culture). Some sections, like the introduction, discussion, and conclusion, are
hard to read and need improvement. Please rearrange this section for better understanding
and make it easier to follow the researcher's thoughts. The discussion must be written more
consistently. Also, the discussion section needs to include the part with the limitations of this
study.
The literature concerning the analyzed factors is nicely cited in the article.
Title: High neutrophil-lymphocyte ratio indicates a worse response to ursodeoxycholic acid in
primary biliary cholangitis: a retrospective cohort study
Version: 2 Date: 06 Oct 2023
Reviewer's report:
In the present manuscript, the authors analyzed how the neutrophil-to lymphocyte ratio might
change depending on the UDCA treatment in PBC patients. The great value of this research is
the large number of patients.
The research described and the conclusions drawn are a good starting point for further analyses
(especially cell culture). Some sections, like the introduction, discussion, and conclusion, are
hard to read and need improvement. Please rearrange this section for better understanding
and make it easier to follow the researcher's thoughts. The discussion must be written more
consistently. Also, the discussion section needs to include the part with the limitations of this
study.
The literature concerning the analyzed factors is nicely cited in the article.
Please review this paper.
user
Title: High neutrophil-lymphocyte ratio indicates a worse response to ursodeoxycholic acid in
primary biliary cholangitis: a retrospective cohort study
Version: 2 Date: 06 Oct 2023
Reviewer's report:
In the present manuscript, the authors analyzed how the neutrophil-to lymphocyte ratio might
change depending on the UDCA treatment in PBC patients. The great value of this research is
the large number of patients.
The research described and the conclusions drawn are a good starting point for further analyses
(especially cell culture). Some sections, like the introduction, discussion, and conclusion, are
hard to read and need improvement. Please rearrange this section for better understanding
and make it easier to follow the researcher's thoughts. The discussion must be written more
consistently. Also, the discussion section needs to include the part with the limitations of this
study.
The literature concerning the analyzed factors is nicely cited in the article.
assistant