Title: SOMATIZATION IN PATIENTS WITH PREDOMINANT DIARRHEA IRRITABLE
BOWEL SYNDROME: THE ROLE OF THE INTESTINAL BARRIER FUNCTION AND
INTEGRITY
Version: 1 Date: 26 Apr 2021
Reviewer's report:
This is a nice study on a topic investigated by other teams. Trying to look for somatization in
IBS is common, but trying to correlate this with intestinal peremability is useful.
Permeability measurement is correct but dysbiosis is not assessed by evaluating microbiota. This
limitation should be commented.
Authors should explain why permeability is  influencing somatization, while most of the
symptoms are not statistically difefrent between low and high somatizers.
Discussion are not well explaining the findings.
Conclusions: first sentence is conceptually wrong.
Title: SOMATIZATION IN PATIENTS WITH PREDOMINANT DIARRHEA IRRITABLE
BOWEL SYNDROME: THE ROLE OF THE INTESTINAL BARRIER FUNCTION AND
INTEGRITY
Version: 1 Date: 26 Apr 2021
Reviewer's report:
This is a nice study on a topic investigated by other teams. Trying to look for somatization in
IBS is common, but trying to correlate this with intestinal peremability is useful.
Permeability measurement is correct but dysbiosis is not assessed by evaluating microbiota. This
limitation should be commented.
Authors should explain why permeability is  influencing somatization, while most of the
symptoms are not statistically difefrent between low and high somatizers.
Discussion are not well explaining the findings.
Conclusions: first sentence is conceptually wrong.
Please review this paper.
user
Title: SOMATIZATION IN PATIENTS WITH PREDOMINANT DIARRHEA IRRITABLE
BOWEL SYNDROME: THE ROLE OF THE INTESTINAL BARRIER FUNCTION AND
INTEGRITY
Version: 1 Date: 26 Apr 2021
Reviewer's report:
This is a nice study on a topic investigated by other teams. Trying to look for somatization in
IBS is common, but trying to correlate this with intestinal peremability is useful.
Permeability measurement is correct but dysbiosis is not assessed by evaluating microbiota. This
limitation should be commented.
Authors should explain why permeability is  influencing somatization, while most of the
symptoms are not statistically difefrent between low and high somatizers.
Discussion are not well explaining the findings.
Conclusions: first sentence is conceptually wrong.
assistant