Reviewer's report
Title:Hepatitis B vs. Hepatitis C Infection on Viral Hepatitis-Associated
Hepatocellular Carcinoma
Version: 2Date:7 April 2012
Reviewer: Sharon Weber
Reviewer's report:
Interesting and unique study that should be published in BMC Gastroenterology.
the MS could be strengthened by addressing the following points:
1. The authors should outline how many pts did not have tissue dx of HCC. In
these pts, how was dx obtained? was this based solely on imaging findings?
2. Re. differences in AFP production, were these results replicated if the cutoff of
nl vs abnl was used vs cutoff of 100?
3. it would be interesting if the authors correlated longterm outcomes (eg RFS,
OS) with hepatitis type.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
'I declare that I have no competing interests'
Reviewer's report
Title:Hepatitis B vs. Hepatitis C Infection on Viral Hepatitis-Associated
Hepatocellular Carcinoma
Version: 2Date:7 April 2012
Reviewer: Sharon Weber
Reviewer's report:
Interesting and unique study that should be published in BMC Gastroenterology.
the MS could be strengthened by addressing the following points:
1. The authors should outline how many pts did not have tissue dx of HCC. In
these pts, how was dx obtained? was this based solely on imaging findings?
2. Re. differences in AFP production, were these results replicated if the cutoff of
nl vs abnl was used vs cutoff of 100?
3. it would be interesting if the authors correlated longterm outcomes (eg RFS,
OS) with hepatitis type.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
'I declare that I have no competing interests'
Please review this paper.
user
Reviewer's report
Title:Hepatitis B vs. Hepatitis C Infection on Viral Hepatitis-Associated
Hepatocellular Carcinoma
Version: 2Date:7 April 2012
Reviewer: Sharon Weber
Reviewer's report:
Interesting and unique study that should be published in BMC Gastroenterology.
the MS could be strengthened by addressing the following points:
1. The authors should outline how many pts did not have tissue dx of HCC. In
these pts, how was dx obtained? was this based solely on imaging findings?
2. Re. differences in AFP production, were these results replicated if the cutoff of
nl vs abnl was used vs cutoff of 100?
3. it would be interesting if the authors correlated longterm outcomes (eg RFS,
OS) with hepatitis type.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
'I declare that I have no competing interests'
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