Reviewer's report
Title:CD44 but not CD24 expressions are related to poor prognosis in noncardia
adenocarcinoma of stomach
Version:3Date:11 July 2014
Reviewer: Baek-hui Kim
Reviewer's report:
Most of previous review comments were responded and corrected. But, I think
that some of them are not appropriately responded.
Major Comulsory Comments
1. Direct reference of tumor classification (except for Lauren classification,
reference #13) or staging was not added to the reference. But, authors added
reference #14, and readers will guess that WHO classification system(2010) and
AJCC 7th edition were used in this study. More specific description is needed.
2. Authors responded that mucinous carcinoma, poorly cohesive carcinoma and
undifferentiated carcinomas were excluded in this study. Poorly cohesive
carcinoma and mucinous carcinomas are major histopathologic types of gastric
adenocarcinoma (more than 20%). Why poorly cohesive carcinomas (signet ring
cell carcinomas) and mucinous carcinomas were exculded in this study?
Minor Essential revisions
1. Table 1. H.p negative, CD24 positive: 36(52.8%) : typing error
Level of interest: An article of limited interest
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
I declare that I have no competing interests
Reviewer's report
Title:CD44 but not CD24 expressions are related to poor prognosis in noncardia
adenocarcinoma of stomach
Version:3Date:11 July 2014
Reviewer: Baek-hui Kim
Reviewer's report:
Most of previous review comments were responded and corrected. But, I think
that some of them are not appropriately responded.
Major Comulsory Comments
1. Direct reference of tumor classification (except for Lauren classification,
reference #13) or staging was not added to the reference. But, authors added
reference #14, and readers will guess that WHO classification system(2010) and
AJCC 7th edition were used in this study. More specific description is needed.
2. Authors responded that mucinous carcinoma, poorly cohesive carcinoma and
undifferentiated carcinomas were excluded in this study. Poorly cohesive
carcinoma and mucinous carcinomas are major histopathologic types of gastric
adenocarcinoma (more than 20%). Why poorly cohesive carcinomas (signet ring
cell carcinomas) and mucinous carcinomas were exculded in this study?
Minor Essential revisions
1. Table 1. H.p negative, CD24 positive: 36(52.8%) : typing error
Level of interest: An article of limited interest
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
I declare that I have no competing interests
Please review this paper.
user
Reviewer's report
Title:CD44 but not CD24 expressions are related to poor prognosis in noncardia
adenocarcinoma of stomach
Version:3Date:11 July 2014
Reviewer: Baek-hui Kim
Reviewer's report:
Most of previous review comments were responded and corrected. But, I think
that some of them are not appropriately responded.
Major Comulsory Comments
1. Direct reference of tumor classification (except for Lauren classification,
reference #13) or staging was not added to the reference. But, authors added
reference #14, and readers will guess that WHO classification system(2010) and
AJCC 7th edition were used in this study. More specific description is needed.
2. Authors responded that mucinous carcinoma, poorly cohesive carcinoma and
undifferentiated carcinomas were excluded in this study. Poorly cohesive
carcinoma and mucinous carcinomas are major histopathologic types of gastric
adenocarcinoma (more than 20%). Why poorly cohesive carcinomas (signet ring
cell carcinomas) and mucinous carcinomas were exculded in this study?
Minor Essential revisions
1. Table 1. H.p negative, CD24 positive: 36(52.8%) : typing error
Level of interest: An article of limited interest
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
I declare that I have no competing interests
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