Title: Age- and sex-stratified detection rates and associated factors of colorectal neoplasia in
the Tianjin colorectal cancer screening program from 2012 to 2020
Version: 0 Date: 10 Jul 2023
Reviewer's report:
This study suggests that stratified colorectal cancer screening strategies based on gender and age
are valid. Participants who were either HRFQ-positive or FIT-positive were defined as high risk
and offered a free colonoscopy to identify colorectal cancer risk factors. The researchers found
that several lifestyle factors, such as smoking, alcohol consumption, and BMI, were associated
with the presence of colorectal lesions in individuals over the age of 50, and found that colorectal
cancer detection increased earlier in men than in women.
The experimental design is well organized, the analytical methods used are valid, and the results
are logically acceptable. Overall, the manuscript presents very interesting and relevant work to
advance our understanding of how risk factors for CRC are related to age and sex. I recommend
that the manuscript be accepted as is.
Title: Age- and sex-stratified detection rates and associated factors of colorectal neoplasia in
the Tianjin colorectal cancer screening program from 2012 to 2020
Version: 0 Date: 10 Jul 2023
Reviewer's report:
This study suggests that stratified colorectal cancer screening strategies based on gender and age
are valid. Participants who were either HRFQ-positive or FIT-positive were defined as high risk
and offered a free colonoscopy to identify colorectal cancer risk factors. The researchers found
that several lifestyle factors, such as smoking, alcohol consumption, and BMI, were associated
with the presence of colorectal lesions in individuals over the age of 50, and found that colorectal
cancer detection increased earlier in men than in women.
The experimental design is well organized, the analytical methods used are valid, and the results
are logically acceptable. Overall, the manuscript presents very interesting and relevant work to
advance our understanding of how risk factors for CRC are related to age and sex. I recommend
that the manuscript be accepted as is.
Please review this paper.
user
Title: Age- and sex-stratified detection rates and associated factors of colorectal neoplasia in
the Tianjin colorectal cancer screening program from 2012 to 2020
Version: 0 Date: 10 Jul 2023
Reviewer's report:
This study suggests that stratified colorectal cancer screening strategies based on gender and age
are valid. Participants who were either HRFQ-positive or FIT-positive were defined as high risk
and offered a free colonoscopy to identify colorectal cancer risk factors. The researchers found
that several lifestyle factors, such as smoking, alcohol consumption, and BMI, were associated
with the presence of colorectal lesions in individuals over the age of 50, and found that colorectal
cancer detection increased earlier in men than in women.
The experimental design is well organized, the analytical methods used are valid, and the results
are logically acceptable. Overall, the manuscript presents very interesting and relevant work to
advance our understanding of how risk factors for CRC are related to age and sex. I recommend
that the manuscript be accepted as is.
assistant