Title: SPATS2 is correlated with cell cycle progression and immune cells infiltration in
hepatocellular carcinoma
Version: 2 Date: 20 Nov 2022
Reviewer:  Amirhossein Hessami
Reviewer's report:
The authors have reported the differential expression, prognostic significance, epigenetic
regulation, immune infiltration of SPATS2 gene in Hepatocellular Carcinoma. The methodology
is well explained and the overall manuscript is well written and clear. However, there are some
comments which could further improve the manuscript.
1- Please add the P-values for hypotheses mentioned through the manuscript.
2- Please mention statistics regarding Hepatocellular carcinomas in Introduction.
Title: SPATS2 is correlated with cell cycle progression and immune cells infiltration in
hepatocellular carcinoma
Version: 2 Date: 20 Nov 2022
Reviewer:  Amirhossein Hessami
Reviewer's report:
The authors have reported the differential expression, prognostic significance, epigenetic
regulation, immune infiltration of SPATS2 gene in Hepatocellular Carcinoma. The methodology
is well explained and the overall manuscript is well written and clear. However, there are some
comments which could further improve the manuscript.
1- Please add the P-values for hypotheses mentioned through the manuscript.
2- Please mention statistics regarding Hepatocellular carcinomas in Introduction.
Please review this paper.
user
Title: SPATS2 is correlated with cell cycle progression and immune cells infiltration in
hepatocellular carcinoma
Version: 2 Date: 20 Nov 2022
Reviewer:  Amirhossein Hessami
Reviewer's report:
The authors have reported the differential expression, prognostic significance, epigenetic
regulation, immune infiltration of SPATS2 gene in Hepatocellular Carcinoma. The methodology
is well explained and the overall manuscript is well written and clear. However, there are some
comments which could further improve the manuscript.
1- Please add the P-values for hypotheses mentioned through the manuscript.
2- Please mention statistics regarding Hepatocellular carcinomas in Introduction.
assistant