Title: Optimizing Outcomes in Acute Pancreatitis: The Impact of of Heparin Therapy Duration
on Mortality in a Multi-Center Retrospective Study
Version: 1 Date: 24 Feb 2025
Reviewer:  Vincenzo Neri
Reviewer's report:
Optimizing Outcomes in Acute Pancreatitis: The Impact of of Heparin Therapy Duration on
Mortality in a Multi-Center Retrospective Study
The Abstract clearly summarizes the contents of the clinical study.
The introduction is correct and frames well the possible therapeutic role of heparin with the
choice of timing of administration in severe pancreatitis.
The Methods with the sections Study design and patients, Data collection, Study outcome,
Statistical analysis, are fully described.
The results are credible and appropriate to the complex approach of the study.
The discussion is developed in a complete and correct manner, highlighting the hypothesis of
the mechanism of action of heparin.
The conclusions are appropriate to the development of the study.
The References are updated and adequate.
The tables and figures are clear and useful in reading and understanding the text
Title: Optimizing Outcomes in Acute Pancreatitis: The Impact of of Heparin Therapy Duration
on Mortality in a Multi-Center Retrospective Study
Version: 1 Date: 24 Feb 2025
Reviewer:  Vincenzo Neri
Reviewer's report:
Optimizing Outcomes in Acute Pancreatitis: The Impact of of Heparin Therapy Duration on
Mortality in a Multi-Center Retrospective Study
The Abstract clearly summarizes the contents of the clinical study.
The introduction is correct and frames well the possible therapeutic role of heparin with the
choice of timing of administration in severe pancreatitis.
The Methods with the sections Study design and patients, Data collection, Study outcome,
Statistical analysis, are fully described.
The results are credible and appropriate to the complex approach of the study.
The discussion is developed in a complete and correct manner, highlighting the hypothesis of
the mechanism of action of heparin.
The conclusions are appropriate to the development of the study.
The References are updated and adequate.
The tables and figures are clear and useful in reading and understanding the text
Please review this paper.
user
Title: Optimizing Outcomes in Acute Pancreatitis: The Impact of of Heparin Therapy Duration
on Mortality in a Multi-Center Retrospective Study
Version: 1 Date: 24 Feb 2025
Reviewer:  Vincenzo Neri
Reviewer's report:
Optimizing Outcomes in Acute Pancreatitis: The Impact of of Heparin Therapy Duration on
Mortality in a Multi-Center Retrospective Study
The Abstract clearly summarizes the contents of the clinical study.
The introduction is correct and frames well the possible therapeutic role of heparin with the
choice of timing of administration in severe pancreatitis.
The Methods with the sections Study design and patients, Data collection, Study outcome,
Statistical analysis, are fully described.
The results are credible and appropriate to the complex approach of the study.
The discussion is developed in a complete and correct manner, highlighting the hypothesis of
the mechanism of action of heparin.
The conclusions are appropriate to the development of the study.
The References are updated and adequate.
The tables and figures are clear and useful in reading and understanding the text
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