Reviewer's report
Title:A retrospective study of acute pancreatitis in patients with hemorrhagic
fever with renal syndrome
Version: 2Date:13 May 2013
Reviewer: Rakesh Kochhar
Reviewer's report:
Major compulsory revisions
The authors describe 6 patients of henorrhagic fever with renal failure who were
deemed to have acute pancreatitis.I am not sure they have made a case for
cause and effect . Even the diagnosis of pancreatitis was questionable in 2
patients with normal enzymes (pain, per se is a common occurrence in HFRF).
Secondly they have not excluded other causes of pancreatitis. There is no
description of alcohol intake or offending drugs. One patient atleast, had gall
stones.
Thirdly autopsy studies with demonstration of the offending agent would actually
clinch the issue. I admit that is not an easy thing to do.
Why can not the 6 patients be having vascular congestion in pancreas as well in
conjunction with other organs. Aren't the authors reading too much in the edema
of the gland ?
Lastly the report conveys a mistaken idea that these patients need to be treated
FOR pancreatitis. I believe the treatment of patients with or wyhout elevated
amylase/lipase will remain the same.
Level of interest: An article of limited interest
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests.
Reviewer's report
Title:A retrospective study of acute pancreatitis in patients with hemorrhagic
fever with renal syndrome
Version: 2Date:13 May 2013
Reviewer: Rakesh Kochhar
Reviewer's report:
Major compulsory revisions
The authors describe 6 patients of henorrhagic fever with renal failure who were
deemed to have acute pancreatitis.I am not sure they have made a case for
cause and effect . Even the diagnosis of pancreatitis was questionable in 2
patients with normal enzymes (pain, per se is a common occurrence in HFRF).
Secondly they have not excluded other causes of pancreatitis. There is no
description of alcohol intake or offending drugs. One patient atleast, had gall
stones.
Thirdly autopsy studies with demonstration of the offending agent would actually
clinch the issue. I admit that is not an easy thing to do.
Why can not the 6 patients be having vascular congestion in pancreas as well in
conjunction with other organs. Aren't the authors reading too much in the edema
of the gland ?
Lastly the report conveys a mistaken idea that these patients need to be treated
FOR pancreatitis. I believe the treatment of patients with or wyhout elevated
amylase/lipase will remain the same.
Level of interest: An article of limited interest
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests.
Please review this paper.
user
Reviewer's report
Title:A retrospective study of acute pancreatitis in patients with hemorrhagic
fever with renal syndrome
Version: 2Date:13 May 2013
Reviewer: Rakesh Kochhar
Reviewer's report:
Major compulsory revisions
The authors describe 6 patients of henorrhagic fever with renal failure who were
deemed to have acute pancreatitis.I am not sure they have made a case for
cause and effect . Even the diagnosis of pancreatitis was questionable in 2
patients with normal enzymes (pain, per se is a common occurrence in HFRF).
Secondly they have not excluded other causes of pancreatitis. There is no
description of alcohol intake or offending drugs. One patient atleast, had gall
stones.
Thirdly autopsy studies with demonstration of the offending agent would actually
clinch the issue. I admit that is not an easy thing to do.
Why can not the 6 patients be having vascular congestion in pancreas as well in
conjunction with other organs. Aren't the authors reading too much in the edema
of the gland ?
Lastly the report conveys a mistaken idea that these patients need to be treated
FOR pancreatitis. I believe the treatment of patients with or wyhout elevated
amylase/lipase will remain the same.
Level of interest: An article of limited interest
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests.
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