Reviewer's report
Title:Low prevalence of 'classical' microscopic colitis but evidence of
microscopic inflammation in Asian patients with diarrhoea predominant irritable
bowel syndrome
Version: 2Date:13 November 2012
Reviewer: Arjuna De silva
Reviewer's report:
There are a few major issues with this article. Firstly the authors say that one of
the objectives of the study is to find the prevalence of microscopic colitis in IBS-D
patients. This is not possible in a single centre study.
The fact that non specific colitis is present in IBS-D is not new. De Silva et al
Scand J Gastroenterol. 2012 ;47:619-24, described this and have included
cytokine data as well. Strangely this paper is not even referenced although it is
methodologically a similar study.
Diverticulitis is also a cause of inflammation and the authors need to mention
that.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Not suitable for publication unless extensively edited
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Reviewer's report
Title:Low prevalence of 'classical' microscopic colitis but evidence of
microscopic inflammation in Asian patients with diarrhoea predominant irritable
bowel syndrome
Version: 2Date:13 November 2012
Reviewer: Arjuna De silva
Reviewer's report:
There are a few major issues with this article. Firstly the authors say that one of
the objectives of the study is to find the prevalence of microscopic colitis in IBS-D
patients. This is not possible in a single centre study.
The fact that non specific colitis is present in IBS-D is not new. De Silva et al
Scand J Gastroenterol. 2012 ;47:619-24, described this and have included
cytokine data as well. Strangely this paper is not even referenced although it is
methodologically a similar study.
Diverticulitis is also a cause of inflammation and the authors need to mention
that.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Not suitable for publication unless extensively edited
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Please review this paper.
user
Reviewer's report
Title:Low prevalence of 'classical' microscopic colitis but evidence of
microscopic inflammation in Asian patients with diarrhoea predominant irritable
bowel syndrome
Version: 2Date:13 November 2012
Reviewer: Arjuna De silva
Reviewer's report:
There are a few major issues with this article. Firstly the authors say that one of
the objectives of the study is to find the prevalence of microscopic colitis in IBS-D
patients. This is not possible in a single centre study.
The fact that non specific colitis is present in IBS-D is not new. De Silva et al
Scand J Gastroenterol. 2012 ;47:619-24, described this and have included
cytokine data as well. Strangely this paper is not even referenced although it is
methodologically a similar study.
Diverticulitis is also a cause of inflammation and the authors need to mention
that.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Not suitable for publication unless extensively edited
Statistical review: No, the manuscript does not need to be seen by a
statistician.
assistant