Title: The expression and clinical significance of CFAP65 in colon cancer
Version: 0 Date: 30 Jan 2024
Reviewer:  Leili Rejali
Reviewer's report:
The manuscript entitled: “The expression and clinical significance of CFAP65 in colon cancer.”
Is concluded that CFAP65 is a potential predictive marker for tumor progression in colon cancer.
The manuscript is well designed but there are some extra points which can help the manuscript
to be improved further.
1-The introduction is weak it must be improved
2-CFAP65 was not evaluated in any other pathological malignancy? The references were all
about spermatogenesis and male infertility.
3-Please define how CFAP65 is relevant with colorectal cancer.
4-Bioinformatic data are not shown, how does the CFAP65 selected through enrichment?
5-Precision medicine is defined in discussion of the manuscript, please discuss about adjuvant
therapy
6-The t-Test is necessary and must be added in the statistics analysis
7-The Roc curve is not designed to designate CFAP65 as a prognostic or diagnostic biomarker.
Title: The expression and clinical significance of CFAP65 in colon cancer
Version: 0 Date: 30 Jan 2024
Reviewer:  Leili Rejali
Reviewer's report:
The manuscript entitled: “The expression and clinical significance of CFAP65 in colon cancer.”
Is concluded that CFAP65 is a potential predictive marker for tumor progression in colon cancer.
The manuscript is well designed but there are some extra points which can help the manuscript
to be improved further.
1-The introduction is weak it must be improved
2-CFAP65 was not evaluated in any other pathological malignancy? The references were all
about spermatogenesis and male infertility.
3-Please define how CFAP65 is relevant with colorectal cancer.
4-Bioinformatic data are not shown, how does the CFAP65 selected through enrichment?
5-Precision medicine is defined in discussion of the manuscript, please discuss about adjuvant
therapy
6-The t-Test is necessary and must be added in the statistics analysis
7-The Roc curve is not designed to designate CFAP65 as a prognostic or diagnostic biomarker.
Please review this paper.
user
Title: The expression and clinical significance of CFAP65 in colon cancer
Version: 0 Date: 30 Jan 2024
Reviewer:  Leili Rejali
Reviewer's report:
The manuscript entitled: “The expression and clinical significance of CFAP65 in colon cancer.”
Is concluded that CFAP65 is a potential predictive marker for tumor progression in colon cancer.
The manuscript is well designed but there are some extra points which can help the manuscript
to be improved further.
1-The introduction is weak it must be improved
2-CFAP65 was not evaluated in any other pathological malignancy? The references were all
about spermatogenesis and male infertility.
3-Please define how CFAP65 is relevant with colorectal cancer.
4-Bioinformatic data are not shown, how does the CFAP65 selected through enrichment?
5-Precision medicine is defined in discussion of the manuscript, please discuss about adjuvant
therapy
6-The t-Test is necessary and must be added in the statistics analysis
7-The Roc curve is not designed to designate CFAP65 as a prognostic or diagnostic biomarker.
assistant