Title: Endoscopic characteristics and treatment modalities of gastrointestinal glomus tumors: a
multicenter retrospective study
Version: 1 Date: 24 Feb 2025
Reviewer:  Hisatomo Ikehara
Reviewer's report:
Overall, this manuscript offers an interesting retrospective analysis on gastrointestinal glomus
tumors, highlighting the diagnostic and therapeutic role of endoscopic procedures. However,
critical revisions are required to address methodological clarity, detailed patient selection,
endpoint definitions, and statistical reporting. Revision is recommended to enhance transparency
and improve scientific rigor.
Comments
Comment 1: Please clarify and expand the patient selection criteria, including explicit inclusion/
exclusion details and the rationale behind the small sample size.
Comment 2: Clearly define primary and secondary endpoints, and improve the statistical
analysis by including confidence intervals and effect sizes.
Comment 3: Expand the discussion on study limitations, particularly regarding the retrospective
design, sample size constraints, and variability in follow-up duration.
Comment 4: Provide clearer indications for choosing endoscopic versus surgical treatment and
elaborate on the clinical applicability of your findings.
Title: Endoscopic characteristics and treatment modalities of gastrointestinal glomus tumors: a
multicenter retrospective study
Version: 1 Date: 24 Feb 2025
Reviewer:  Hisatomo Ikehara
Reviewer's report:
Overall, this manuscript offers an interesting retrospective analysis on gastrointestinal glomus
tumors, highlighting the diagnostic and therapeutic role of endoscopic procedures. However,
critical revisions are required to address methodological clarity, detailed patient selection,
endpoint definitions, and statistical reporting. Revision is recommended to enhance transparency
and improve scientific rigor.
Comments
Comment 1: Please clarify and expand the patient selection criteria, including explicit inclusion/
exclusion details and the rationale behind the small sample size.
Comment 2: Clearly define primary and secondary endpoints, and improve the statistical
analysis by including confidence intervals and effect sizes.
Comment 3: Expand the discussion on study limitations, particularly regarding the retrospective
design, sample size constraints, and variability in follow-up duration.
Comment 4: Provide clearer indications for choosing endoscopic versus surgical treatment and
elaborate on the clinical applicability of your findings.
Please review this paper.
user
Title: Endoscopic characteristics and treatment modalities of gastrointestinal glomus tumors: a
multicenter retrospective study
Version: 1 Date: 24 Feb 2025
Reviewer:  Hisatomo Ikehara
Reviewer's report:
Overall, this manuscript offers an interesting retrospective analysis on gastrointestinal glomus
tumors, highlighting the diagnostic and therapeutic role of endoscopic procedures. However,
critical revisions are required to address methodological clarity, detailed patient selection,
endpoint definitions, and statistical reporting. Revision is recommended to enhance transparency
and improve scientific rigor.
Comments
Comment 1: Please clarify and expand the patient selection criteria, including explicit inclusion/
exclusion details and the rationale behind the small sample size.
Comment 2: Clearly define primary and secondary endpoints, and improve the statistical
analysis by including confidence intervals and effect sizes.
Comment 3: Expand the discussion on study limitations, particularly regarding the retrospective
design, sample size constraints, and variability in follow-up duration.
Comment 4: Provide clearer indications for choosing endoscopic versus surgical treatment and
elaborate on the clinical applicability of your findings.
assistant