Reviewer's report
Title:Metabonomics analysis of liver tissues in
d-galactosamine/lipopolysaccharide induced acute hepatic failure BALB/c mice
Version: 2Date:17 January 2013
Reviewer: Antonio Fontanellas
Reviewer's report:
Major Compulsory Revisions
It is important to relate the observed changes in the liver with the plasma during
the induction of AFL. The authors say in their cover letter that "we are performing
further analysis on the difference." In my opinion, the decision to publish this
article should wait until these analyzes are included and they establish a
satisfactory discussion of the differences obtained in the results obtained in
plasma and liver samples.
The author must respond to these before a decision on publication can be
reached.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interest.
Reviewer's report
Title:Metabonomics analysis of liver tissues in
d-galactosamine/lipopolysaccharide induced acute hepatic failure BALB/c mice
Version: 2Date:17 January 2013
Reviewer: Antonio Fontanellas
Reviewer's report:
Major Compulsory Revisions
It is important to relate the observed changes in the liver with the plasma during
the induction of AFL. The authors say in their cover letter that "we are performing
further analysis on the difference." In my opinion, the decision to publish this
article should wait until these analyzes are included and they establish a
satisfactory discussion of the differences obtained in the results obtained in
plasma and liver samples.
The author must respond to these before a decision on publication can be
reached.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interest.
Please review this paper.
user
Reviewer's report
Title:Metabonomics analysis of liver tissues in
d-galactosamine/lipopolysaccharide induced acute hepatic failure BALB/c mice
Version: 2Date:17 January 2013
Reviewer: Antonio Fontanellas
Reviewer's report:
Major Compulsory Revisions
It is important to relate the observed changes in the liver with the plasma during
the induction of AFL. The authors say in their cover letter that "we are performing
further analysis on the difference." In my opinion, the decision to publish this
article should wait until these analyzes are included and they establish a
satisfactory discussion of the differences obtained in the results obtained in
plasma and liver samples.
The author must respond to these before a decision on publication can be
reached.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interest.
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