Title: A novel missense mutation of the STK11 gene in a Chinese family with Peutz-Jeghers
syndrome
Version: 1 Date: 19 Nov 2022
Reviewer:  Zi-ye Zhao
Reviewer's report:
The purpose of this study is to report a novel missense mutation of the STK11 gene in a Chinese
family with Peutz-Jeghers syndrome. The design of this study is comprehensive, but there are
a few problems. So it is suggested to be re-submitted after revision. The main problems are as
follows:
1. The description of the proband's medical history is somewhat tedious, especially the section
on bile duct cancer.
2. Please add a scale to the image and improve the resolution of pathological images.
3. The authors should carefully check the full text, including grammar mistakes. The manuscript
should be corrected by a native English speaker who is a specialist.
Title: A novel missense mutation of the STK11 gene in a Chinese family with Peutz-Jeghers
syndrome
Version: 1 Date: 19 Nov 2022
Reviewer:  Zi-ye Zhao
Reviewer's report:
The purpose of this study is to report a novel missense mutation of the STK11 gene in a Chinese
family with Peutz-Jeghers syndrome. The design of this study is comprehensive, but there are
a few problems. So it is suggested to be re-submitted after revision. The main problems are as
follows:
1. The description of the proband's medical history is somewhat tedious, especially the section
on bile duct cancer.
2. Please add a scale to the image and improve the resolution of pathological images.
3. The authors should carefully check the full text, including grammar mistakes. The manuscript
should be corrected by a native English speaker who is a specialist.
Please review this paper.
user
Title: A novel missense mutation of the STK11 gene in a Chinese family with Peutz-Jeghers
syndrome
Version: 1 Date: 19 Nov 2022
Reviewer:  Zi-ye Zhao
Reviewer's report:
The purpose of this study is to report a novel missense mutation of the STK11 gene in a Chinese
family with Peutz-Jeghers syndrome. The design of this study is comprehensive, but there are
a few problems. So it is suggested to be re-submitted after revision. The main problems are as
follows:
1. The description of the proband's medical history is somewhat tedious, especially the section
on bile duct cancer.
2. Please add a scale to the image and improve the resolution of pathological images.
3. The authors should carefully check the full text, including grammar mistakes. The manuscript
should be corrected by a native English speaker who is a specialist.
assistant