Title: Comparison of the efficacy and tolerability of elobixibat plus sodium picosulfate
with magnesium citrate and split-dose 2-L polyethylene glycol with ascorbic acid for bowel
preparation before outpatient colonoscopy: A study protocol for the multicentre, randomised,
controlled E-PLUS trial
Version: 1 Date: 14 Oct 2023
Reviewer's report:
The protocol is interesting, well designed and the results of the study potentially usefull.
I have only some concerns regarding the following issues:
-The introduction in extremely redundant. Several concepts have been repeated several times
and because of this quite boring for the readers
- One issue to be considered and that could affect the diffusion of the proposed new cleansing
protocol is the cost of elobixibat.
-Some clinical data regarding elobixibat should be provided
Title: Comparison of the efficacy and tolerability of elobixibat plus sodium picosulfate
with magnesium citrate and split-dose 2-L polyethylene glycol with ascorbic acid for bowel
preparation before outpatient colonoscopy: A study protocol for the multicentre, randomised,
controlled E-PLUS trial
Version: 1 Date: 14 Oct 2023
Reviewer's report:
The protocol is interesting, well designed and the results of the study potentially usefull.
I have only some concerns regarding the following issues:
-The introduction in extremely redundant. Several concepts have been repeated several times
and because of this quite boring for the readers
- One issue to be considered and that could affect the diffusion of the proposed new cleansing
protocol is the cost of elobixibat.
-Some clinical data regarding elobixibat should be provided
Please review this paper.
user
Title: Comparison of the efficacy and tolerability of elobixibat plus sodium picosulfate
with magnesium citrate and split-dose 2-L polyethylene glycol with ascorbic acid for bowel
preparation before outpatient colonoscopy: A study protocol for the multicentre, randomised,
controlled E-PLUS trial
Version: 1 Date: 14 Oct 2023
Reviewer's report:
The protocol is interesting, well designed and the results of the study potentially usefull.
I have only some concerns regarding the following issues:
-The introduction in extremely redundant. Several concepts have been repeated several times
and because of this quite boring for the readers
- One issue to be considered and that could affect the diffusion of the proposed new cleansing
protocol is the cost of elobixibat.
-Some clinical data regarding elobixibat should be provided
assistant