Title: Predictors of pathological complete response after total neoadjuvant treatment using short
course radiotherapy for locally advanced rectal cancer
Version: 3 Date: 12 Feb 2025
Reviewer:  Mattia Falchetto Osti
Reviewer's report:
Interesting mono-institutional retrospective series of TNT for LARC where radiation was
delivered with 2 different short term schedules.
Results are in line with published data and confirm efficacy of TNT
Title: Predictors of pathological complete response after total neoadjuvant treatment using short
course radiotherapy for locally advanced rectal cancer
Version: 3 Date: 12 Feb 2025
Reviewer:  Mattia Falchetto Osti
Reviewer's report:
Interesting mono-institutional retrospective series of TNT for LARC where radiation was
delivered with 2 different short term schedules.
Results are in line with published data and confirm efficacy of TNT
Please review this paper.
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Title: Predictors of pathological complete response after total neoadjuvant treatment using short
course radiotherapy for locally advanced rectal cancer
Version: 3 Date: 12 Feb 2025
Reviewer:  Mattia Falchetto Osti
Reviewer's report:
Interesting mono-institutional retrospective series of TNT for LARC where radiation was
delivered with 2 different short term schedules.
Results are in line with published data and confirm efficacy of TNT
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