Title: Differential effects of systemic immune inflammation indices on hepatic steatosis and
hepatic fibrosis: evidence from NHANES 1999-2018
Version: 0 Date: 18 Nov 2024
Reviewer:  Panagiotis Tsibouris
Reviewer's report:
NHANES provides the opportunity to get data of patient transient elastography , generaly more
reliable to estimate liver fibrosis than the bunch of nomogrammes authors selected Abstract
Number of patients belongs in the results Methods Numerical values of patients included and
excluded for various reasons in the study belong in the results Only description of entry and
exclusion criterai belongs to methods section  All patients with underlined liver diseases should
be excluded apart from MASLD patients Use of alcohol should be defined so that patients with
MetSLD and ALD could be excluded Use of MASLD definition instead of NAFLD would be
preferable Description of comorbidies and demographic factors included should be described
as in the entry criteria of NHANES Statistics Power of the study should be calculated Results
Significant differences in demographic factors and various comorbidies should be presented in
the text
Title: Differential effects of systemic immune inflammation indices on hepatic steatosis and
hepatic fibrosis: evidence from NHANES 1999-2018
Version: 0 Date: 18 Nov 2024
Reviewer:  Panagiotis Tsibouris
Reviewer's report:
NHANES provides the opportunity to get data of patient transient elastography , generaly more
reliable to estimate liver fibrosis than the bunch of nomogrammes authors selected Abstract
Number of patients belongs in the results Methods Numerical values of patients included and
excluded for various reasons in the study belong in the results Only description of entry and
exclusion criterai belongs to methods section  All patients with underlined liver diseases should
be excluded apart from MASLD patients Use of alcohol should be defined so that patients with
MetSLD and ALD could be excluded Use of MASLD definition instead of NAFLD would be
preferable Description of comorbidies and demographic factors included should be described
as in the entry criteria of NHANES Statistics Power of the study should be calculated Results
Significant differences in demographic factors and various comorbidies should be presented in
the text
Please review this paper.
user
Title: Differential effects of systemic immune inflammation indices on hepatic steatosis and
hepatic fibrosis: evidence from NHANES 1999-2018
Version: 0 Date: 18 Nov 2024
Reviewer:  Panagiotis Tsibouris
Reviewer's report:
NHANES provides the opportunity to get data of patient transient elastography , generaly more
reliable to estimate liver fibrosis than the bunch of nomogrammes authors selected Abstract
Number of patients belongs in the results Methods Numerical values of patients included and
excluded for various reasons in the study belong in the results Only description of entry and
exclusion criterai belongs to methods section  All patients with underlined liver diseases should
be excluded apart from MASLD patients Use of alcohol should be defined so that patients with
MetSLD and ALD could be excluded Use of MASLD definition instead of NAFLD would be
preferable Description of comorbidies and demographic factors included should be described
as in the entry criteria of NHANES Statistics Power of the study should be calculated Results
Significant differences in demographic factors and various comorbidies should be presented in
the text
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