Title: Correlation and Prognostic Implications of Intratumor and Tumor Draining Lymph Node
Foxp3+ T Regulatory Cells in Colorectal Cancer
Version: 1 Date: 01 Jan 2022
Reviewer's report:
1, How the authors defined TDLNs in this study? It is better to clearly show the definition of
TDLNs.
2, In Table 1, high abundance of Tregs in tumor and TDLNs were observed in T3-4, however
the authors claimed ‘both of which were more common in early T stages’.
3, In Table3, node involvement was skipped in multivariate analysis, but it seems important to
include the factor of node involvement, particularly in the study for TDLNs.
Title: Correlation and Prognostic Implications of Intratumor and Tumor Draining Lymph Node
Foxp3+ T Regulatory Cells in Colorectal Cancer
Version: 1 Date: 01 Jan 2022
Reviewer's report:
1, How the authors defined TDLNs in this study? It is better to clearly show the definition of
TDLNs.
2, In Table 1, high abundance of Tregs in tumor and TDLNs were observed in T3-4, however
the authors claimed ‘both of which were more common in early T stages’.
3, In Table3, node involvement was skipped in multivariate analysis, but it seems important to
include the factor of node involvement, particularly in the study for TDLNs.
Please review this paper.
user
Title: Correlation and Prognostic Implications of Intratumor and Tumor Draining Lymph Node
Foxp3+ T Regulatory Cells in Colorectal Cancer
Version: 1 Date: 01 Jan 2022
Reviewer's report:
1, How the authors defined TDLNs in this study? It is better to clearly show the definition of
TDLNs.
2, In Table 1, high abundance of Tregs in tumor and TDLNs were observed in T3-4, however
the authors claimed ‘both of which were more common in early T stages’.
3, In Table3, node involvement was skipped in multivariate analysis, but it seems important to
include the factor of node involvement, particularly in the study for TDLNs.
assistant