Title: Comparisonof surgical and oncologic outcomes in very elderly patients (# 80 years old)
and elderly (65-79 years old) colorectal cancer patients: Apropensity score matching
Version: 3 Date: 06 Feb 2022
Reviewer's report:
Cheng and colleagues present a study comparing the performance of "elderly" and "very elderly"
patients  after colorectal cancer surgery. Though the topic is highly current and lacks proper
investigation, the presented work has major flaws:
- Throughout the manuscript and figures, p values lower than 0.0001 are written as "0.000". I
suspect that these numbers were directly copied from SPSS. These p values should be revised.
- The manuscript has major flaws in English grammar and general readability. I strongly
recommend proof-reading by a native speaker.
- Figure 2: The Kaplan-Meier curves are screenshots from SPSS taken from the standard output.
In a revision, these should be adapted to an own design.
- Multivariate analyses of factors impacting overall und disease-free survival were carried out
on the whole population of elderly and very elderly patients. The results were as expected and do
not give new insights. The following analyses would be interesting to see: multivariate analyses
of only the very elderly patients and with these outcome parameters: hospital stay, postoperative
complications.
Title: Comparisonof surgical and oncologic outcomes in very elderly patients (# 80 years old)
and elderly (65-79 years old) colorectal cancer patients: Apropensity score matching
Version: 3 Date: 06 Feb 2022
Reviewer's report:
Cheng and colleagues present a study comparing the performance of "elderly" and "very elderly"
patients  after colorectal cancer surgery. Though the topic is highly current and lacks proper
investigation, the presented work has major flaws:
- Throughout the manuscript and figures, p values lower than 0.0001 are written as "0.000". I
suspect that these numbers were directly copied from SPSS. These p values should be revised.
- The manuscript has major flaws in English grammar and general readability. I strongly
recommend proof-reading by a native speaker.
- Figure 2: The Kaplan-Meier curves are screenshots from SPSS taken from the standard output.
In a revision, these should be adapted to an own design.
- Multivariate analyses of factors impacting overall und disease-free survival were carried out
on the whole population of elderly and very elderly patients. The results were as expected and do
not give new insights. The following analyses would be interesting to see: multivariate analyses
of only the very elderly patients and with these outcome parameters: hospital stay, postoperative
complications.
Please review this paper.
user
Title: Comparisonof surgical and oncologic outcomes in very elderly patients (# 80 years old)
and elderly (65-79 years old) colorectal cancer patients: Apropensity score matching
Version: 3 Date: 06 Feb 2022
Reviewer's report:
Cheng and colleagues present a study comparing the performance of "elderly" and "very elderly"
patients  after colorectal cancer surgery. Though the topic is highly current and lacks proper
investigation, the presented work has major flaws:
- Throughout the manuscript and figures, p values lower than 0.0001 are written as "0.000". I
suspect that these numbers were directly copied from SPSS. These p values should be revised.
- The manuscript has major flaws in English grammar and general readability. I strongly
recommend proof-reading by a native speaker.
- Figure 2: The Kaplan-Meier curves are screenshots from SPSS taken from the standard output.
In a revision, these should be adapted to an own design.
- Multivariate analyses of factors impacting overall und disease-free survival were carried out
on the whole population of elderly and very elderly patients. The results were as expected and do
not give new insights. The following analyses would be interesting to see: multivariate analyses
of only the very elderly patients and with these outcome parameters: hospital stay, postoperative
complications.
assistant