Reviewer's report
Title:Gene expression analysis of a Helicobacter pylori-infected and high-salt
diet-treated mouse gastric tumor model: Identification of CD177 as a novel
prognostic factor in patients with gastric cancer
Version: 2Date:21 May 2013
Reviewer: Matteo Fassan
Reviewer's report:
In the new version of the manuscript the authors adequately answered to almost
all the concerns raised by the two reviewers. However, there are two main
problems:
1) the authors previously presented data obtained as for probes, instead of
considering the single genes...in the new version of the manuscript they lost one
over three most important genes. I would suggest to review the GEO files from
an external biostatistician.
2) a survival of >80 months remains strange to me for an advanced gastric
adenocarcinoma.
Thus, I cannot make a final decision on this manuscript.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: Yes, and I have assessed the statistics in my report.
Declaration of competing interests:
'I declare I have no competing interests'
Reviewer's report
Title:Gene expression analysis of a Helicobacter pylori-infected and high-salt
diet-treated mouse gastric tumor model: Identification of CD177 as a novel
prognostic factor in patients with gastric cancer
Version: 2Date:21 May 2013
Reviewer: Matteo Fassan
Reviewer's report:
In the new version of the manuscript the authors adequately answered to almost
all the concerns raised by the two reviewers. However, there are two main
problems:
1) the authors previously presented data obtained as for probes, instead of
considering the single genes...in the new version of the manuscript they lost one
over three most important genes. I would suggest to review the GEO files from
an external biostatistician.
2) a survival of >80 months remains strange to me for an advanced gastric
adenocarcinoma.
Thus, I cannot make a final decision on this manuscript.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: Yes, and I have assessed the statistics in my report.
Declaration of competing interests:
'I declare I have no competing interests'
Please review this paper.
user
Reviewer's report
Title:Gene expression analysis of a Helicobacter pylori-infected and high-salt
diet-treated mouse gastric tumor model: Identification of CD177 as a novel
prognostic factor in patients with gastric cancer
Version: 2Date:21 May 2013
Reviewer: Matteo Fassan
Reviewer's report:
In the new version of the manuscript the authors adequately answered to almost
all the concerns raised by the two reviewers. However, there are two main
problems:
1) the authors previously presented data obtained as for probes, instead of
considering the single genes...in the new version of the manuscript they lost one
over three most important genes. I would suggest to review the GEO files from
an external biostatistician.
2) a survival of >80 months remains strange to me for an advanced gastric
adenocarcinoma.
Thus, I cannot make a final decision on this manuscript.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: Yes, and I have assessed the statistics in my report.
Declaration of competing interests:
'I declare I have no competing interests'
assistant