Title: Accumulation of rare earth elements in human gallstones: a perspective from dietary and
human health
Version: 1 Date: 30 Jun 2024
Reviewer:  Nuria Güil-Oumrait
Reviewer's report:
Dear authors,
This manuscript presents a very interesting study with an innovative research framework. The
rationale behind the study is well argued, and the writing is clear and concise. However, it lacks
an acknowledgment of the study's limitations and future research directions resulting from the
findings.
Some minor comments are specified below:
Abstract:
• Background: Reformulate the main aim of the paper to enhance clarity.
• Limit the use of abbreviations. When abbreviations are used for the first time, provide their
full form (e.g., UCC, LREE, and HREE).
Introduction:
• Line 45: Briefly mention the chemical properties or provide examples that differentiate LREE,
MREE, and HREE.
• Line 61: Clarify if you mean "more than 60% of biliary tract cancer patients."
• Line 80: Correct "countries”.
Discussion / Conclusions:
• Please add a section discussing the study's limitations and suggest directions for future research.
Title: Accumulation of rare earth elements in human gallstones: a perspective from dietary and
human health
Version: 1 Date: 30 Jun 2024
Reviewer:  Nuria Güil-Oumrait
Reviewer's report:
Dear authors,
This manuscript presents a very interesting study with an innovative research framework. The
rationale behind the study is well argued, and the writing is clear and concise. However, it lacks
an acknowledgment of the study's limitations and future research directions resulting from the
findings.
Some minor comments are specified below:
Abstract:
• Background: Reformulate the main aim of the paper to enhance clarity.
• Limit the use of abbreviations. When abbreviations are used for the first time, provide their
full form (e.g., UCC, LREE, and HREE).
Introduction:
• Line 45: Briefly mention the chemical properties or provide examples that differentiate LREE,
MREE, and HREE.
• Line 61: Clarify if you mean "more than 60% of biliary tract cancer patients."
• Line 80: Correct "countries”.
Discussion / Conclusions:
• Please add a section discussing the study's limitations and suggest directions for future research.
Please review this paper.
user
Title: Accumulation of rare earth elements in human gallstones: a perspective from dietary and
human health
Version: 1 Date: 30 Jun 2024
Reviewer:  Nuria Güil-Oumrait
Reviewer's report:
Dear authors,
This manuscript presents a very interesting study with an innovative research framework. The
rationale behind the study is well argued, and the writing is clear and concise. However, it lacks
an acknowledgment of the study's limitations and future research directions resulting from the
findings.
Some minor comments are specified below:
Abstract:
• Background: Reformulate the main aim of the paper to enhance clarity.
• Limit the use of abbreviations. When abbreviations are used for the first time, provide their
full form (e.g., UCC, LREE, and HREE).
Introduction:
• Line 45: Briefly mention the chemical properties or provide examples that differentiate LREE,
MREE, and HREE.
• Line 61: Clarify if you mean "more than 60% of biliary tract cancer patients."
• Line 80: Correct "countries”.
Discussion / Conclusions:
• Please add a section discussing the study's limitations and suggest directions for future research.
assistant