Title: The prognostic significance of tumor-specific growth factor in colorectal cancer: An
observation study
Version: 2 Date: 16 Mar 2025
Reviewer's report:
Dear author,
The study has a very high number of patients and deals with a really nice and important topic.
I see that it has some shortcomings, but these are not the shortcomings of the article but rather
our general shortcomings regarding TM markers. Tm markers rank high among the unnecessary
tests. Adding a new test to these will create a new problem that will confront us clinicians with
patients. Besides all these, this is a study that will make an important contribution to the medical
literature. I can list the deficiencies that I personally see and need to be corrected as follows.
1- The material and method section should be detailed.
2- The discussion section mostly emphasizes the material and method. Also, the studies
compared are very limited. There are studies with Tm markers and comparing and detailing
them will contribute. In addition, if descriptive information is included in the introduction, the
study will be simple and better understood.
I wish you success.
Title: The prognostic significance of tumor-specific growth factor in colorectal cancer: An
observation study
Version: 2 Date: 16 Mar 2025
Reviewer's report:
Dear author,
The study has a very high number of patients and deals with a really nice and important topic.
I see that it has some shortcomings, but these are not the shortcomings of the article but rather
our general shortcomings regarding TM markers. Tm markers rank high among the unnecessary
tests. Adding a new test to these will create a new problem that will confront us clinicians with
patients. Besides all these, this is a study that will make an important contribution to the medical
literature. I can list the deficiencies that I personally see and need to be corrected as follows.
1- The material and method section should be detailed.
2- The discussion section mostly emphasizes the material and method. Also, the studies
compared are very limited. There are studies with Tm markers and comparing and detailing
them will contribute. In addition, if descriptive information is included in the introduction, the
study will be simple and better understood.
I wish you success.
Please review this paper.
user
Title: The prognostic significance of tumor-specific growth factor in colorectal cancer: An
observation study
Version: 2 Date: 16 Mar 2025
Reviewer's report:
Dear author,
The study has a very high number of patients and deals with a really nice and important topic.
I see that it has some shortcomings, but these are not the shortcomings of the article but rather
our general shortcomings regarding TM markers. Tm markers rank high among the unnecessary
tests. Adding a new test to these will create a new problem that will confront us clinicians with
patients. Besides all these, this is a study that will make an important contribution to the medical
literature. I can list the deficiencies that I personally see and need to be corrected as follows.
1- The material and method section should be detailed.
2- The discussion section mostly emphasizes the material and method. Also, the studies
compared are very limited. There are studies with Tm markers and comparing and detailing
them will contribute. In addition, if descriptive information is included in the introduction, the
study will be simple and better understood.
I wish you success.
assistant