Reviewer’s report
Title: Biliary mucinous cystic neoplasm mimicking a hydatid cyst: a case report and literature review
Version: 2 Date: 05 Dec 2018
Reviewer: Prasenjit Das
Reviewer's report:
Please include all comments for the authors in this box rather than uploading your report as an  
attachment. Please only upload as attachments annotated versions of manuscripts, graphs, supporting  
materials or other aspects of your report which cannot be included in a text format.
Please overwrite this text when adding your comments to the authors.
The  authors  have  described  a  case  of  multiloculated  biliary  cystadenoma,  which  preoperatively  
mimicked a hydatic cyst. 
Though, this entity is not new and the authors have acknowledged this is a table, I think that more  
systematic workup would have given a correct preoperative diagnosis.
The authors have mentioned presence of calcification in radiology images, which is not apparent in  
figure 1. Please include a representative picture and put an indicative arrow. 
Preoperative eosinophil count was normal and radiological features were not typical of a hydatid cyst.  
The author should mention pre-operative serum IgE level. Please mention that. Moreover serum CA 19  
9 level was also not mentioned in the manuscript.
Are the methods appropriate and well described?
If not, please specify what is required in your comments to the authors.
Yes
Does the work include the necessary controls?
If not, please specify which controls are required in your comments to the authors.
Unable to assess
Are the conclusions drawn adequately supported by the data shown?
If not, please explain in your comments to the authors.
Yes
Are you able to assess any statistics in the manuscript or would you recommend an additional  
statistical review?
If  an  additional  statistical  review  is  recommended,  please  specify  what  aspects  require  further  
assessment in your comments to the editors.
Not relevant to this manuscript
Quality of written English
Please indicate the quality of language in the manuscript:
Acceptable
Declaration of competing interests
Please complete a declaration of competing interests, considering the following questions:
1. Have you in the past five years received reimbursements, fees, funding, or salary from an  
organisation  that  may  in  any  way  gain  or  lose  financially  from  the  publication  of  this  
manuscript, either now or in the future?
2. Do you hold any stocks or shares in an organisation that may in any way gain or lose financially  
from the publication of this manuscript, either now or in the future?
3. Do  you  hold  or are  you  currently applying  for  any patents  relating  to  the  content  of  the  
manuscript?
4. Have you received reimbursements, fees, funding, or salary from an organization that holds or  
has applied for patents relating to the content of the manuscript?
5. Do you have any other financial competing interests?
6. Do you have any non-financial competing interests in relation to this paper?
If you can answer no to all of the above, write 'I declare that I have no competing interests' below. If  
your reply is yes to any, please give details below.
I declare that I have no competing interests
I agree to the open peer review policy of the journal. I understand that my name will be included on my  
report to the authors and, if the manuscript is accepted for publication, my named report including any 
attachments I upload will be posted on the website along with the authors' responses. I agree for my 
report to be made available under an Open Access Creative Commons CC-BY license 
(http://creativecommons.org/licenses/by/4.0/ ). I understand that any comments which I do not wish to 
be included in my named report can be included as confidential comments to the editors, which will not  
be published.
I agree to the open peer review policy of the journal
Reviewer’s report
Title: Biliary mucinous cystic neoplasm mimicking a hydatid cyst: a case report and literature review
Version: 2 Date: 05 Dec 2018
Reviewer: Prasenjit Das
Reviewer's report:
Please include all comments for the authors in this box rather than uploading your report as an  
attachment. Please only upload as attachments annotated versions of manuscripts, graphs, supporting  
materials or other aspects of your report which cannot be included in a text format.
Please overwrite this text when adding your comments to the authors.
The  authors  have  described  a  case  of  multiloculated  biliary  cystadenoma,  which  preoperatively  
mimicked a hydatic cyst. 
Though, this entity is not new and the authors have acknowledged this is a table, I think that more  
systematic workup would have given a correct preoperative diagnosis.
The authors have mentioned presence of calcification in radiology images, which is not apparent in  
figure 1. Please include a representative picture and put an indicative arrow. 
Preoperative eosinophil count was normal and radiological features were not typical of a hydatid cyst.  
The author should mention pre-operative serum IgE level. Please mention that. Moreover serum CA 19  
9 level was also not mentioned in the manuscript.
Are the methods appropriate and well described?
If not, please specify what is required in your comments to the authors.
Yes
Does the work include the necessary controls?
If not, please specify which controls are required in your comments to the authors.
Unable to assess
Are the conclusions drawn adequately supported by the data shown?
If not, please explain in your comments to the authors.
Yes
Are you able to assess any statistics in the manuscript or would you recommend an additional  
statistical review?
If  an  additional  statistical  review  is  recommended,  please  specify  what  aspects  require  further  
assessment in your comments to the editors.
Not relevant to this manuscript
Quality of written English
Please indicate the quality of language in the manuscript:
Acceptable
Declaration of competing interests
Please complete a declaration of competing interests, considering the following questions:
1. Have you in the past five years received reimbursements, fees, funding, or salary from an  
organisation  that  may  in  any  way  gain  or  lose  financially  from  the  publication  of  this  
manuscript, either now or in the future?
2. Do you hold any stocks or shares in an organisation that may in any way gain or lose financially  
from the publication of this manuscript, either now or in the future?
3. Do  you  hold  or are  you  currently applying  for  any patents  relating  to  the  content  of  the  
manuscript?
4. Have you received reimbursements, fees, funding, or salary from an organization that holds or  
has applied for patents relating to the content of the manuscript?
5. Do you have any other financial competing interests?
6. Do you have any non-financial competing interests in relation to this paper?
If you can answer no to all of the above, write 'I declare that I have no competing interests' below. If  
your reply is yes to any, please give details below.
I declare that I have no competing interests
I agree to the open peer review policy of the journal. I understand that my name will be included on my  
report to the authors and, if the manuscript is accepted for publication, my named report including any 
attachments I upload will be posted on the website along with the authors' responses. I agree for my 
report to be made available under an Open Access Creative Commons CC-BY license 
(http://creativecommons.org/licenses/by/4.0/ ). I understand that any comments which I do not wish to 
be included in my named report can be included as confidential comments to the editors, which will not  
be published.
I agree to the open peer review policy of the journal
Please review this paper.
user
Reviewer’s report
Title: Biliary mucinous cystic neoplasm mimicking a hydatid cyst: a case report and literature review
Version: 2 Date: 05 Dec 2018
Reviewer: Prasenjit Das
Reviewer's report:
Please include all comments for the authors in this box rather than uploading your report as an  
attachment. Please only upload as attachments annotated versions of manuscripts, graphs, supporting  
materials or other aspects of your report which cannot be included in a text format.
Please overwrite this text when adding your comments to the authors.
The  authors  have  described  a  case  of  multiloculated  biliary  cystadenoma,  which  preoperatively  
mimicked a hydatic cyst. 
Though, this entity is not new and the authors have acknowledged this is a table, I think that more  
systematic workup would have given a correct preoperative diagnosis.
The authors have mentioned presence of calcification in radiology images, which is not apparent in  
figure 1. Please include a representative picture and put an indicative arrow. 
Preoperative eosinophil count was normal and radiological features were not typical of a hydatid cyst.  
The author should mention pre-operative serum IgE level. Please mention that. Moreover serum CA 19  
9 level was also not mentioned in the manuscript.
Are the methods appropriate and well described?
If not, please specify what is required in your comments to the authors.
Yes
Does the work include the necessary controls?
If not, please specify which controls are required in your comments to the authors.
Unable to assess
Are the conclusions drawn adequately supported by the data shown?
If not, please explain in your comments to the authors.
Yes
Are you able to assess any statistics in the manuscript or would you recommend an additional  
statistical review?
If  an  additional  statistical  review  is  recommended,  please  specify  what  aspects  require  further  
assessment in your comments to the editors.
Not relevant to this manuscript
Quality of written English
Please indicate the quality of language in the manuscript:
Acceptable
Declaration of competing interests
Please complete a declaration of competing interests, considering the following questions:
1. Have you in the past five years received reimbursements, fees, funding, or salary from an  
organisation  that  may  in  any  way  gain  or  lose  financially  from  the  publication  of  this  
manuscript, either now or in the future?
2. Do you hold any stocks or shares in an organisation that may in any way gain or lose financially  
from the publication of this manuscript, either now or in the future?
3. Do  you  hold  or are  you  currently applying  for  any patents  relating  to  the  content  of  the  
manuscript?
4. Have you received reimbursements, fees, funding, or salary from an organization that holds or  
has applied for patents relating to the content of the manuscript?
5. Do you have any other financial competing interests?
6. Do you have any non-financial competing interests in relation to this paper?
If you can answer no to all of the above, write 'I declare that I have no competing interests' below. If  
your reply is yes to any, please give details below.
I declare that I have no competing interests
I agree to the open peer review policy of the journal. I understand that my name will be included on my  
report to the authors and, if the manuscript is accepted for publication, my named report including any 
attachments I upload will be posted on the website along with the authors' responses. I agree for my 
report to be made available under an Open Access Creative Commons CC-BY license 
(http://creativecommons.org/licenses/by/4.0/ ). I understand that any comments which I do not wish to 
be included in my named report can be included as confidential comments to the editors, which will not  
be published.
I agree to the open peer review policy of the journal
assistant