Title: Association between adhering to a dietary approach to stop hypertension and risk of
colorectal cancers: A systematic review and meta-analysis
Version: 3 Date: 27 Feb 2025
Reviewer's report:
1) The authors should include the PRISMA checklist as part of the supplementary material.
2) It is recommended that the authors update their search strategy to ensure it is current.
3) For cohort studies, the authors should utilize the ROBINS-E tool for risk of bias assessment,
as it is a more appropriate tool compared to NOS.
4) The authors should specify which heterogeneity estimator was used in their analysis.
5) The authors should implement and present the GRADE approach.
6) The data analysis has been conducted incorrectly by combining Odds Ratios (OR) and Hazard
Ratios (HR), which may lead to misleading conclusions. Separate analyses should be performed
for studies using OR and those using HR.
7) The assessment of publication bias should be conducted separately for studies using HR and
those using OR, rather than across the total number of included studies, as they have different
effect sizes.
8) The discussion section should be revised. Simply presenting studies included in the meta-
analysis does not provide additional value to the manuscript.
9) The authors should compare their findings with studies evaluating adherence to the DASH
diet and its association with cancer risk or other health outcomes, such as diabetes mellitus
and hypertension. Additionally, they should explore potential molecular and pathophysiological
mechanisms underlying concordant or contradictory findings.
10) The limitations section should be expanded to include additional relevant limitations that
have not been addressed.
11) The authors should clarify the novel contributions of this review in comparison
to previously published reviews, specifically referring to the following studies:
[PMID: 31418286](https://pubmed.ncbi.nlm.nih.gov/31418286/) and [PMID: 32063407]
(https://pubmed.ncbi.nlm.nih.gov/32063407/).
Title: Association between adhering to a dietary approach to stop hypertension and risk of
colorectal cancers: A systematic review and meta-analysis
Version: 3 Date: 27 Feb 2025
Reviewer's report:
1) The authors should include the PRISMA checklist as part of the supplementary material.
2) It is recommended that the authors update their search strategy to ensure it is current.
3) For cohort studies, the authors should utilize the ROBINS-E tool for risk of bias assessment,
as it is a more appropriate tool compared to NOS.
4) The authors should specify which heterogeneity estimator was used in their analysis.
5) The authors should implement and present the GRADE approach.
6) The data analysis has been conducted incorrectly by combining Odds Ratios (OR) and Hazard
Ratios (HR), which may lead to misleading conclusions. Separate analyses should be performed
for studies using OR and those using HR.
7) The assessment of publication bias should be conducted separately for studies using HR and
those using OR, rather than across the total number of included studies, as they have different
effect sizes.
8) The discussion section should be revised. Simply presenting studies included in the meta-
analysis does not provide additional value to the manuscript.
9) The authors should compare their findings with studies evaluating adherence to the DASH
diet and its association with cancer risk or other health outcomes, such as diabetes mellitus
and hypertension. Additionally, they should explore potential molecular and pathophysiological
mechanisms underlying concordant or contradictory findings.
10) The limitations section should be expanded to include additional relevant limitations that
have not been addressed.
11) The authors should clarify the novel contributions of this review in comparison
to previously published reviews, specifically referring to the following studies:
[PMID: 31418286](https://pubmed.ncbi.nlm.nih.gov/31418286/) and [PMID: 32063407]
(https://pubmed.ncbi.nlm.nih.gov/32063407/).
Please review this paper.
user
Title: Association between adhering to a dietary approach to stop hypertension and risk of
colorectal cancers: A systematic review and meta-analysis
Version: 3 Date: 27 Feb 2025
Reviewer's report:
1) The authors should include the PRISMA checklist as part of the supplementary material.
2) It is recommended that the authors update their search strategy to ensure it is current.
3) For cohort studies, the authors should utilize the ROBINS-E tool for risk of bias assessment,
as it is a more appropriate tool compared to NOS.
4) The authors should specify which heterogeneity estimator was used in their analysis.
5) The authors should implement and present the GRADE approach.
6) The data analysis has been conducted incorrectly by combining Odds Ratios (OR) and Hazard
Ratios (HR), which may lead to misleading conclusions. Separate analyses should be performed
for studies using OR and those using HR.
7) The assessment of publication bias should be conducted separately for studies using HR and
those using OR, rather than across the total number of included studies, as they have different
effect sizes.
8) The discussion section should be revised. Simply presenting studies included in the meta-
analysis does not provide additional value to the manuscript.
9) The authors should compare their findings with studies evaluating adherence to the DASH
diet and its association with cancer risk or other health outcomes, such as diabetes mellitus
and hypertension. Additionally, they should explore potential molecular and pathophysiological
mechanisms underlying concordant or contradictory findings.
10) The limitations section should be expanded to include additional relevant limitations that
have not been addressed.
11) The authors should clarify the novel contributions of this review in comparison
to previously published reviews, specifically referring to the following studies:
[PMID: 31418286](https://pubmed.ncbi.nlm.nih.gov/31418286/) and [PMID: 32063407]
(https://pubmed.ncbi.nlm.nih.gov/32063407/).
assistant