Title: Identification of Helicobacter pylori-Related Gastric Cancer Risk Using Serological
Gastritis Markers and Endoscopic Findings: A Large-Scale Retrospective Cohort Study
Version: 1 Date: 06 May 2022
Reviewer's report:
I read with interest  the paper on "Identification of gastric cancer risk using serological gastritis
markers and endoscopic findings: a large-scale retrospective cohort study"
The paper is well written and the study is well conducted.
I have some comments:
- Abstract: Results: non easy to read, group is not defined; not clear when and in who endoscopy
was performed
- Methods: I wonder why autoimmune gastritis has been excluded. When the scope of the study
was that to investigate Hp-related GC risk, this should be expressed in the title of the paper
- Mehtods & Results: Iwould suggest to include the diagnostic performance (sensitivity,
specificity, PPV, NPV) of serological markers  alone versus serological marker plus endoscopy
to highlight the diagnostic gain when both diagnostic methods were combined.
Title: Identification of Helicobacter pylori-Related Gastric Cancer Risk Using Serological
Gastritis Markers and Endoscopic Findings: A Large-Scale Retrospective Cohort Study
Version: 1 Date: 06 May 2022
Reviewer's report:
I read with interest  the paper on "Identification of gastric cancer risk using serological gastritis
markers and endoscopic findings: a large-scale retrospective cohort study"
The paper is well written and the study is well conducted.
I have some comments:
- Abstract: Results: non easy to read, group is not defined; not clear when and in who endoscopy
was performed
- Methods: I wonder why autoimmune gastritis has been excluded. When the scope of the study
was that to investigate Hp-related GC risk, this should be expressed in the title of the paper
- Mehtods & Results: Iwould suggest to include the diagnostic performance (sensitivity,
specificity, PPV, NPV) of serological markers  alone versus serological marker plus endoscopy
to highlight the diagnostic gain when both diagnostic methods were combined.
Please review this paper.
user
Title: Identification of Helicobacter pylori-Related Gastric Cancer Risk Using Serological
Gastritis Markers and Endoscopic Findings: A Large-Scale Retrospective Cohort Study
Version: 1 Date: 06 May 2022
Reviewer's report:
I read with interest  the paper on "Identification of gastric cancer risk using serological gastritis
markers and endoscopic findings: a large-scale retrospective cohort study"
The paper is well written and the study is well conducted.
I have some comments:
- Abstract: Results: non easy to read, group is not defined; not clear when and in who endoscopy
was performed
- Methods: I wonder why autoimmune gastritis has been excluded. When the scope of the study
was that to investigate Hp-related GC risk, this should be expressed in the title of the paper
- Mehtods & Results: Iwould suggest to include the diagnostic performance (sensitivity,
specificity, PPV, NPV) of serological markers  alone versus serological marker plus endoscopy
to highlight the diagnostic gain when both diagnostic methods were combined.
assistant