Title: Anti-CdtB and anti-vinculin antibodies to diagnose irritable bowel syndrome in
inflammatory bowel disease patients
Version: 3 Date: 19 Aug 2024
Reviewer's report:
I congratulate the authors for choosing this topic and doing such a nice study.
I only have a few criticisms
1. I suggest that detailed information be provided about the ethics committee approval number
and which ethics committee it is
2. A more detailed explanation should be provided on how the cut-off values for anti-CdtB and
anti-vinculin were found.
3.It is not stated which drugs IBD patients use. Could steroids and subsequent anti-TNF agents,
which are used intensively especially during activation periods, have an effect on these markers?
This issue should be clarified.
Title: Anti-CdtB and anti-vinculin antibodies to diagnose irritable bowel syndrome in
inflammatory bowel disease patients
Version: 3 Date: 19 Aug 2024
Reviewer's report:
I congratulate the authors for choosing this topic and doing such a nice study.
I only have a few criticisms
1. I suggest that detailed information be provided about the ethics committee approval number
and which ethics committee it is
2. A more detailed explanation should be provided on how the cut-off values for anti-CdtB and
anti-vinculin were found.
3.It is not stated which drugs IBD patients use. Could steroids and subsequent anti-TNF agents,
which are used intensively especially during activation periods, have an effect on these markers?
This issue should be clarified.
Please review this paper.
user
Title: Anti-CdtB and anti-vinculin antibodies to diagnose irritable bowel syndrome in
inflammatory bowel disease patients
Version: 3 Date: 19 Aug 2024
Reviewer's report:
I congratulate the authors for choosing this topic and doing such a nice study.
I only have a few criticisms
1. I suggest that detailed information be provided about the ethics committee approval number
and which ethics committee it is
2. A more detailed explanation should be provided on how the cut-off values for anti-CdtB and
anti-vinculin were found.
3.It is not stated which drugs IBD patients use. Could steroids and subsequent anti-TNF agents,
which are used intensively especially during activation periods, have an effect on these markers?
This issue should be clarified.
assistant