Reviewer's report
Title:Synchronous Appendiceal and Intramucosal Gastric Signet Ring Cell
Carcinomas in an Individual with CDH1-associated Hereditary Diffuse Gastric
Carcinoma: a Case Report of a Novel Association and Review of the Literature
Version: 1Date:7 June 2013
Reviewer: Theodore Liakakos
Reviewer's report:
The authors are presenting the first case in the literature of an appendiceal signet
ring cell carcinoma with synchronous CDH1-associated hereditary diffuse gastric
cancer in a female patient. They also make a comprehensive analysis of the
current
literature about familial gastric cancer and associated malignancies.
Though I would have thought that they should had focused more on coexisting
other malignancies I think that their report adds to the literature and should be
published.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests
Reviewer's report
Title:Synchronous Appendiceal and Intramucosal Gastric Signet Ring Cell
Carcinomas in an Individual with CDH1-associated Hereditary Diffuse Gastric
Carcinoma: a Case Report of a Novel Association and Review of the Literature
Version: 1Date:7 June 2013
Reviewer: Theodore Liakakos
Reviewer's report:
The authors are presenting the first case in the literature of an appendiceal signet
ring cell carcinoma with synchronous CDH1-associated hereditary diffuse gastric
cancer in a female patient. They also make a comprehensive analysis of the
current
literature about familial gastric cancer and associated malignancies.
Though I would have thought that they should had focused more on coexisting
other malignancies I think that their report adds to the literature and should be
published.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests
Please review this paper.
user
Reviewer's report
Title:Synchronous Appendiceal and Intramucosal Gastric Signet Ring Cell
Carcinomas in an Individual with CDH1-associated Hereditary Diffuse Gastric
Carcinoma: a Case Report of a Novel Association and Review of the Literature
Version: 1Date:7 June 2013
Reviewer: Theodore Liakakos
Reviewer's report:
The authors are presenting the first case in the literature of an appendiceal signet
ring cell carcinoma with synchronous CDH1-associated hereditary diffuse gastric
cancer in a female patient. They also make a comprehensive analysis of the
current
literature about familial gastric cancer and associated malignancies.
Though I would have thought that they should had focused more on coexisting
other malignancies I think that their report adds to the literature and should be
published.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests
assistant