Title: Risk of cardiovascular disease in lean patients with nonalcoholic fatty liver disease
Version: 2 Date: 07 May 2023
Reviewer's report:
This study investigated whether there is a difference in CVD incidence between lean
NAFLD and non-lean NAFLD by cohort survey. Known CVD risks (diabetes, dyslipidemia,
hypertension) were not significant explanatory variables in the multivariable analysis. This
means that the number of cases in this cohort is not sufficient to verify CVD risk. Therefore,
the authors cannot conclude that there is no significant difference in CVD incidence beween
NAFLD and non-lean NAFLD from this cohort study. Nor has it been verified whether lean
NAFLD has a significantly higher CVD incidence than non-NAFLD. If this point was verified,
the significance of the study may have increased.
Title: Risk of cardiovascular disease in lean patients with nonalcoholic fatty liver disease
Version: 2 Date: 07 May 2023
Reviewer's report:
This study investigated whether there is a difference in CVD incidence between lean
NAFLD and non-lean NAFLD by cohort survey. Known CVD risks (diabetes, dyslipidemia,
hypertension) were not significant explanatory variables in the multivariable analysis. This
means that the number of cases in this cohort is not sufficient to verify CVD risk. Therefore,
the authors cannot conclude that there is no significant difference in CVD incidence beween
NAFLD and non-lean NAFLD from this cohort study. Nor has it been verified whether lean
NAFLD has a significantly higher CVD incidence than non-NAFLD. If this point was verified,
the significance of the study may have increased.
Please review this paper.
user
Title: Risk of cardiovascular disease in lean patients with nonalcoholic fatty liver disease
Version: 2 Date: 07 May 2023
Reviewer's report:
This study investigated whether there is a difference in CVD incidence between lean
NAFLD and non-lean NAFLD by cohort survey. Known CVD risks (diabetes, dyslipidemia,
hypertension) were not significant explanatory variables in the multivariable analysis. This
means that the number of cases in this cohort is not sufficient to verify CVD risk. Therefore,
the authors cannot conclude that there is no significant difference in CVD incidence beween
NAFLD and non-lean NAFLD from this cohort study. Nor has it been verified whether lean
NAFLD has a significantly higher CVD incidence than non-NAFLD. If this point was verified,
the significance of the study may have increased.
assistant