Reviewer ’s report  
 
Title: Metabolic Status and Lifestyle Factors associated with G allbladder Polyps: A Covariance 
Structure Analysis  
 
Version: 0 Date: 22 Jul 2018  
 
Reviewer: Quadri Alabi  
 
Reviewer's report:  
 
Review report of "Metabolic Status and Lifestyle Factors ass ociated with Gallbladder Polyps: A 
Covariance Structure Analysis"  
 
 
The work is good, it shows the metabolic status and lifestyle factors in association with 
gallbladder polyps. The authors will do well to explain in details the proper pathway or 
mechanism r esponsible for the link between metabolic and lifestyle factors in association with 
gallbladder polyps (discussion session).  
 
 
Page 6; line 118: examined should be remove.  
 
 
Line 150; page 7: Recast this statement "Physical activity was investigated the freque ncies and 
duration of participants attending light, moderate, or  vigorous physical activities in the past 
months"  
 
 
Authors should explain the method of collection of blood (serum or plasma?) in methodology 
session.  
 
 
Overall, the study contributed to the exi sting knowledge and also give a link to the effect of 
lifestyle factors in relation to development of gallbladder polyps, but more rigorous future 
studies have to be done on these high rising incidence. This study is just a pointer.  
 
 
 
 
 
 
 
 
 
 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
Yes 
 
Does the work include the necessary controls?  
If not, please spe cify which controls are required in your comments to the authors.  
 
Yes 
 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in the manuscript or w ould you recommend an 
additional statistical review?  
If an additional statistical review is recommended, please speci fy what aspects require further 
assessment in your comments to the editors.  
 
I am able to assess the statistics  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Needs some language corrections before being published  
 
Declaration of competing interests  
Please complete a declaration of competing in terests, considering the following questions:  
 
1. Have you in the past five years received reimbursements, f ees, funding, or salary from an 
organisation that may in any way gain or lose financial ly from the publication of this 
manuscript, either now or in t he future?  
 
2. Do you hold any stocks or shares in an organisation t hat may in any way gain or lose 
financially from the publication of this manuscript, either now or in the future?  
 
3. Do you hold or are you currently applying for any patents relating to th e content of the 
manuscript?  
 
4. Have you received reimbursements, fees, funding, or salary from an organization that 
holds or has applied for patents relating to the content of the manuscript?  
 
5. Do you have any other financial competing interests?  
 
6. Do y ou have any non -financial competing interests in relation to this paper?  
If you can answer no to all of the above, write 'I declare that I have  no competing interests'  
below. If your reply is yes to any, please give details below.  
 
No competing interest  
 
I agree to the open pe er review policy of the journal. I understan d that my name will be included 
on my report to the authors and, if the manuscript is accepted f or publication, my named report 
including any attachments I upload will be posted on the website along with the auth ors' 
responses. I agree for my report to be made available under an Open Access Creative Commons 
CC-BY license ( http://creativecommons.org/licenses/by/4.0/ ). I understand that any comments 
which I do not wish to be included in my named report can be includ ed as confidential comments 
to the editor s, which will not be published.  
 
I agree to the open peer review policy of the journal  
Reviewer ’s report  
 
Title: Metabolic Status and Lifestyle Factors associated with G allbladder Polyps: A Covariance 
Structure Analysis  
 
Version: 0 Date: 22 Jul 2018  
 
Reviewer: Quadri Alabi  
 
Reviewer's report:  
 
Review report of "Metabolic Status and Lifestyle Factors ass ociated with Gallbladder Polyps: A 
Covariance Structure Analysis"  
 
 
The work is good, it shows the metabolic status and lifestyle factors in association with 
gallbladder polyps. The authors will do well to explain in details the proper pathway or 
mechanism r esponsible for the link between metabolic and lifestyle factors in association with 
gallbladder polyps (discussion session).  
 
 
Page 6; line 118: examined should be remove.  
 
 
Line 150; page 7: Recast this statement "Physical activity was investigated the freque ncies and 
duration of participants attending light, moderate, or  vigorous physical activities in the past 
months"  
 
 
Authors should explain the method of collection of blood (serum or plasma?) in methodology 
session.  
 
 
Overall, the study contributed to the exi sting knowledge and also give a link to the effect of 
lifestyle factors in relation to development of gallbladder polyps, but more rigorous future 
studies have to be done on these high rising incidence. This study is just a pointer.  
 
 
 
 
 
 
 
 
 
 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
Yes 
 
Does the work include the necessary controls?  
If not, please spe cify which controls are required in your comments to the authors.  
 
Yes 
 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in the manuscript or w ould you recommend an 
additional statistical review?  
If an additional statistical review is recommended, please speci fy what aspects require further 
assessment in your comments to the editors.  
 
I am able to assess the statistics  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Needs some language corrections before being published  
 
Declaration of competing interests  
Please complete a declaration of competing in terests, considering the following questions:  
 
1. Have you in the past five years received reimbursements, f ees, funding, or salary from an 
organisation that may in any way gain or lose financial ly from the publication of this 
manuscript, either now or in t he future?  
 
2. Do you hold any stocks or shares in an organisation t hat may in any way gain or lose 
financially from the publication of this manuscript, either now or in the future?  
 
3. Do you hold or are you currently applying for any patents relating to th e content of the 
manuscript?  
 
4. Have you received reimbursements, fees, funding, or salary from an organization that 
holds or has applied for patents relating to the content of the manuscript?  
 
5. Do you have any other financial competing interests?  
 
6. Do y ou have any non -financial competing interests in relation to this paper?  
If you can answer no to all of the above, write 'I declare that I have  no competing interests'  
below. If your reply is yes to any, please give details below.  
 
No competing interest  
 
I agree to the open pe er review policy of the journal. I understan d that my name will be included 
on my report to the authors and, if the manuscript is accepted f or publication, my named report 
including any attachments I upload will be posted on the website along with the auth ors' 
responses. I agree for my report to be made available under an Open Access Creative Commons 
CC-BY license ( http://creativecommons.org/licenses/by/4.0/ ). I understand that any comments 
which I do not wish to be included in my named report can be includ ed as confidential comments 
to the editor s, which will not be published.  
 
I agree to the open peer review policy of the journal  
Please review this paper.
user
Reviewer ’s report  
 
Title: Metabolic Status and Lifestyle Factors associated with G allbladder Polyps: A Covariance 
Structure Analysis  
 
Version: 0 Date: 22 Jul 2018  
 
Reviewer: Quadri Alabi  
 
Reviewer's report:  
 
Review report of "Metabolic Status and Lifestyle Factors ass ociated with Gallbladder Polyps: A 
Covariance Structure Analysis"  
 
 
The work is good, it shows the metabolic status and lifestyle factors in association with 
gallbladder polyps. The authors will do well to explain in details the proper pathway or 
mechanism r esponsible for the link between metabolic and lifestyle factors in association with 
gallbladder polyps (discussion session).  
 
 
Page 6; line 118: examined should be remove.  
 
 
Line 150; page 7: Recast this statement "Physical activity was investigated the freque ncies and 
duration of participants attending light, moderate, or  vigorous physical activities in the past 
months"  
 
 
Authors should explain the method of collection of blood (serum or plasma?) in methodology 
session.  
 
 
Overall, the study contributed to the exi sting knowledge and also give a link to the effect of 
lifestyle factors in relation to development of gallbladder polyps, but more rigorous future 
studies have to be done on these high rising incidence. This study is just a pointer.  
 
 
 
 
 
 
 
 
 
 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
Yes 
 
Does the work include the necessary controls?  
If not, please spe cify which controls are required in your comments to the authors.  
 
Yes 
 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in the manuscript or w ould you recommend an 
additional statistical review?  
If an additional statistical review is recommended, please speci fy what aspects require further 
assessment in your comments to the editors.  
 
I am able to assess the statistics  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Needs some language corrections before being published  
 
Declaration of competing interests  
Please complete a declaration of competing in terests, considering the following questions:  
 
1. Have you in the past five years received reimbursements, f ees, funding, or salary from an 
organisation that may in any way gain or lose financial ly from the publication of this 
manuscript, either now or in t he future?  
 
2. Do you hold any stocks or shares in an organisation t hat may in any way gain or lose 
financially from the publication of this manuscript, either now or in the future?  
 
3. Do you hold or are you currently applying for any patents relating to th e content of the 
manuscript?  
 
4. Have you received reimbursements, fees, funding, or salary from an organization that 
holds or has applied for patents relating to the content of the manuscript?  
 
5. Do you have any other financial competing interests?  
 
6. Do y ou have any non -financial competing interests in relation to this paper?  
If you can answer no to all of the above, write 'I declare that I have  no competing interests'  
below. If your reply is yes to any, please give details below.  
 
No competing interest  
 
I agree to the open pe er review policy of the journal. I understan d that my name will be included 
on my report to the authors and, if the manuscript is accepted f or publication, my named report 
including any attachments I upload will be posted on the website along with the auth ors' 
responses. I agree for my report to be made available under an Open Access Creative Commons 
CC-BY license ( http://creativecommons.org/licenses/by/4.0/ ). I understand that any comments 
which I do not wish to be included in my named report can be includ ed as confidential comments 
to the editor s, which will not be published.  
 
I agree to the open peer review policy of the journal  
assistant