Title: Alterations of Liver Enzymes and Lipid Profile in Response to Exhaustive Eccentric
Exercise: Vitamin D supplementation trial in Overweight Females with Non-Alcoholic Fatty
Liver Disease
Version: 5 Date: 13 Jul 2022
Reviewer's report:
Even though they corrected the data part, sentences in the background and discussion are not
clear. I think still they need to focus on sentences.
1. In page 3- “The prevalence of Vit D deficiency in the Vatandost et al. (2018) meta-analysis
study was reported as 56% of the total population, 64% of women, and 44 % of men”
They can say like “ according to Vatandost et al. (2018) meta-analysis, the prevalence of Vit D
deficiency in the total population was 56%. Among these Vit D deficiency population, 64% of
people are women, and 44 % are men”
2. In page 3- In general, long-term Vit D supplementation has an anti-fibrotic and anti-
inflammatory role that improves lipid profile and liver enzymes in NAFLD patients [15, 16].
However, few studies have investigated the effect of short-term Vit D supplementation on lipid
profile and liver enzymes alterations following EEE in these patients. Therefore, in this study,
we conducted a randomized controlled trial (RCT) to investigate the effect of short-term Vit D
on the liver enzymes and lipid profile responses to EEE in the overweight female with NAFLD.
I would recommend revising one more time.
Title: Alterations of Liver Enzymes and Lipid Profile in Response to Exhaustive Eccentric
Exercise: Vitamin D supplementation trial in Overweight Females with Non-Alcoholic Fatty
Liver Disease
Version: 5 Date: 13 Jul 2022
Reviewer's report:
Even though they corrected the data part, sentences in the background and discussion are not
clear. I think still they need to focus on sentences.
1. In page 3- “The prevalence of Vit D deficiency in the Vatandost et al. (2018) meta-analysis
study was reported as 56% of the total population, 64% of women, and 44 % of men”
They can say like “ according to Vatandost et al. (2018) meta-analysis, the prevalence of Vit D
deficiency in the total population was 56%. Among these Vit D deficiency population, 64% of
people are women, and 44 % are men”
2. In page 3- In general, long-term Vit D supplementation has an anti-fibrotic and anti-
inflammatory role that improves lipid profile and liver enzymes in NAFLD patients [15, 16].
However, few studies have investigated the effect of short-term Vit D supplementation on lipid
profile and liver enzymes alterations following EEE in these patients. Therefore, in this study,
we conducted a randomized controlled trial (RCT) to investigate the effect of short-term Vit D
on the liver enzymes and lipid profile responses to EEE in the overweight female with NAFLD.
I would recommend revising one more time.
Please review this paper.
user
Title: Alterations of Liver Enzymes and Lipid Profile in Response to Exhaustive Eccentric
Exercise: Vitamin D supplementation trial in Overweight Females with Non-Alcoholic Fatty
Liver Disease
Version: 5 Date: 13 Jul 2022
Reviewer's report:
Even though they corrected the data part, sentences in the background and discussion are not
clear. I think still they need to focus on sentences.
1. In page 3- “The prevalence of Vit D deficiency in the Vatandost et al. (2018) meta-analysis
study was reported as 56% of the total population, 64% of women, and 44 % of men”
They can say like “ according to Vatandost et al. (2018) meta-analysis, the prevalence of Vit D
deficiency in the total population was 56%. Among these Vit D deficiency population, 64% of
people are women, and 44 % are men”
2. In page 3- In general, long-term Vit D supplementation has an anti-fibrotic and anti-
inflammatory role that improves lipid profile and liver enzymes in NAFLD patients [15, 16].
However, few studies have investigated the effect of short-term Vit D supplementation on lipid
profile and liver enzymes alterations following EEE in these patients. Therefore, in this study,
we conducted a randomized controlled trial (RCT) to investigate the effect of short-term Vit D
on the liver enzymes and lipid profile responses to EEE in the overweight female with NAFLD.
I would recommend revising one more time.
assistant