Title: Glepaglutide, a novel glucagon-like peptide-2 agonist, has anti-inflammatory and mucosal
regenerative effects in an experimental model of inflammatory bowel disease in rats
Version: 1 Date: 12 Dec 2022
Reviewer's report:
Authors studies Glepaglutide anti-inflammatory and intestinotrophic effects  in a rat model
of small intestinal inflammation.  demonstrationg that Glepaglutide co- and post-treatment
significantly reduced  inflammation,  increased small intestinal mass, indicating intestinal
regenerative effects.
The introduction is clear and well written, I have no commet about it.
I suggest to perform hystology on intestine in order to assess the inflammatory infiltrate and
changes in mucosa aspects.
I think that the paper is of interest after these enrichment in results
Title: Glepaglutide, a novel glucagon-like peptide-2 agonist, has anti-inflammatory and mucosal
regenerative effects in an experimental model of inflammatory bowel disease in rats
Version: 1 Date: 12 Dec 2022
Reviewer's report:
Authors studies Glepaglutide anti-inflammatory and intestinotrophic effects  in a rat model
of small intestinal inflammation.  demonstrationg that Glepaglutide co- and post-treatment
significantly reduced  inflammation,  increased small intestinal mass, indicating intestinal
regenerative effects.
The introduction is clear and well written, I have no commet about it.
I suggest to perform hystology on intestine in order to assess the inflammatory infiltrate and
changes in mucosa aspects.
I think that the paper is of interest after these enrichment in results
Please review this paper.
user
Title: Glepaglutide, a novel glucagon-like peptide-2 agonist, has anti-inflammatory and mucosal
regenerative effects in an experimental model of inflammatory bowel disease in rats
Version: 1 Date: 12 Dec 2022
Reviewer's report:
Authors studies Glepaglutide anti-inflammatory and intestinotrophic effects  in a rat model
of small intestinal inflammation.  demonstrationg that Glepaglutide co- and post-treatment
significantly reduced  inflammation,  increased small intestinal mass, indicating intestinal
regenerative effects.
The introduction is clear and well written, I have no commet about it.
I suggest to perform hystology on intestine in order to assess the inflammatory infiltrate and
changes in mucosa aspects.
I think that the paper is of interest after these enrichment in results
assistant