Title: Statin Use and the Risk of Hepatocellular Carcinoma Among Patients With Chronic
Hepatitis B: An Emulated Target Trial Using Longitudinal Nationwide Population Cohort Data
Version: 1 Date: 10 Aug 2023
Reviewer's report:
1. This study is a  good idea to find if statin use can reduce the recurrence risk of HCC.
2. From your data base, I think that you can find when the patient started statin use (in starin
use group). However, can you find when the patient "out" statin use ?(that means if the patient
discontinue the stain use after include into the in statin use group). In such condition, how do
you category this patient ?
Title: Statin Use and the Risk of Hepatocellular Carcinoma Among Patients With Chronic
Hepatitis B: An Emulated Target Trial Using Longitudinal Nationwide Population Cohort Data
Version: 1 Date: 10 Aug 2023
Reviewer's report:
1. This study is a  good idea to find if statin use can reduce the recurrence risk of HCC.
2. From your data base, I think that you can find when the patient started statin use (in starin
use group). However, can you find when the patient "out" statin use ?(that means if the patient
discontinue the stain use after include into the in statin use group). In such condition, how do
you category this patient ?
Please review this paper.
user
Title: Statin Use and the Risk of Hepatocellular Carcinoma Among Patients With Chronic
Hepatitis B: An Emulated Target Trial Using Longitudinal Nationwide Population Cohort Data
Version: 1 Date: 10 Aug 2023
Reviewer's report:
1. This study is a  good idea to find if statin use can reduce the recurrence risk of HCC.
2. From your data base, I think that you can find when the patient started statin use (in starin
use group). However, can you find when the patient "out" statin use ?(that means if the patient
discontinue the stain use after include into the in statin use group). In such condition, how do
you category this patient ?
assistant