Reviewer ’s report  
Title:  HIGH PREVALENCE OF ADVANCED C OLORECTAL NEOPLASIA IN THE THAI 
POPULATION: A PROSPECTIVE SCREENING COLONOSCOPY OF 1,404 CASE S 
 
Version : 0 Date:  13 Dec 2015  
 
Reviewer : Adam Dziki  
 
Reviewer's report:  
This paper is dealing with an old topic. This may be is new in Thailand. Unfortunately the 
number of patients is small for such analysis. There is also some misunderstanding. In the text  is 
written that the group of patients selected for colonoscopy did not present any symptoms from 
the alimentary tract. In the table there is listed small group of them, which had the symptoms. 
There is a question if in this group there was another finding  that in the other group. There is also 
similar issue. In the text there is written that the patients did not have any family history of CRC 
but in the table there is shown a group of patients with the history of family CRC. There is also 
no information in  this paper if this group of patients had any other findings in the colonoscopy.  
The findings in this paper are well known and there is nothing new in this paper so I leave the 
decision to the Chief -Editor  
 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
Yes 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to  the authors.  
Unable to assess  
  
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
Yes 
Are you able to assess any statistics in the manuscript or would you recommend an 
additional statistica l review?  
If an additional statistical review is recommended, please specify what aspects require further 
assessment in your comments to the editors.  
I am able to assess the statistics  
Quality of written English  
Please indicate the quality of language i n the manuscript:  
Acceptable  
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following questions:  
1. Have you in the past five years received reimbursements, f ees, funding, or salary from an 
organisation that may in any way gain or lose financially from the publi cation of this 
manuscript, either now or in the future?  
2. Do you hold any stocks or shares in an organisation t hat may in any way gain or lose 
financially from the publication of this manuscript, either now or in the future?  
3. Do you hold or are you curr ently applying for any patents  relating to the content of the 
manuscript?  
4. Have you received reimbursements, fees, funding, or salary from an organization that 
holds  or has applied for patents relating to the content of the manuscript?  
5. Do you have any  other financial competing interests?  
6. Do you have any non -financial competing interests in relation to this paper?  
If you can answer no to all of the above, write 'I declare that I have no competing interests' 
below. If your reply is yes to any, please give details below.  
None 
I agree to the open peer review policy of the journal. I understand that my name will be included 
on my report t o the authors and, if the manuscript is accepted for publication, my named report 
including any attachments I upload will be posted on the website along with the authors' 
responses. I agree for my report to be made available under an Open Access Creative C ommons 
CC-BY license ( http://creativecommons.org/licenses/by/4.0/ ). I understand that any comments 
which I do not wish to be included in my named report can be included as confidential comments 
to the editors, which will not be published.  
I agree to the ope n peer review policy of the journal  
Reviewer ’s report  
Title:  HIGH PREVALENCE OF ADVANCED C OLORECTAL NEOPLASIA IN THE THAI 
POPULATION: A PROSPECTIVE SCREENING COLONOSCOPY OF 1,404 CASE S 
 
Version : 0 Date:  13 Dec 2015  
 
Reviewer : Adam Dziki  
 
Reviewer's report:  
This paper is dealing with an old topic. This may be is new in Thailand. Unfortunately the 
number of patients is small for such analysis. There is also some misunderstanding. In the text  is 
written that the group of patients selected for colonoscopy did not present any symptoms from 
the alimentary tract. In the table there is listed small group of them, which had the symptoms. 
There is a question if in this group there was another finding  that in the other group. There is also 
similar issue. In the text there is written that the patients did not have any family history of CRC 
but in the table there is shown a group of patients with the history of family CRC. There is also 
no information in  this paper if this group of patients had any other findings in the colonoscopy.  
The findings in this paper are well known and there is nothing new in this paper so I leave the 
decision to the Chief -Editor  
 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
Yes 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to  the authors.  
Unable to assess  
  
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
Yes 
Are you able to assess any statistics in the manuscript or would you recommend an 
additional statistica l review?  
If an additional statistical review is recommended, please specify what aspects require further 
assessment in your comments to the editors.  
I am able to assess the statistics  
Quality of written English  
Please indicate the quality of language i n the manuscript:  
Acceptable  
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following questions:  
1. Have you in the past five years received reimbursements, f ees, funding, or salary from an 
organisation that may in any way gain or lose financially from the publi cation of this 
manuscript, either now or in the future?  
2. Do you hold any stocks or shares in an organisation t hat may in any way gain or lose 
financially from the publication of this manuscript, either now or in the future?  
3. Do you hold or are you curr ently applying for any patents  relating to the content of the 
manuscript?  
4. Have you received reimbursements, fees, funding, or salary from an organization that 
holds  or has applied for patents relating to the content of the manuscript?  
5. Do you have any  other financial competing interests?  
6. Do you have any non -financial competing interests in relation to this paper?  
If you can answer no to all of the above, write 'I declare that I have no competing interests' 
below. If your reply is yes to any, please give details below.  
None 
I agree to the open peer review policy of the journal. I understand that my name will be included 
on my report t o the authors and, if the manuscript is accepted for publication, my named report 
including any attachments I upload will be posted on the website along with the authors' 
responses. I agree for my report to be made available under an Open Access Creative C ommons 
CC-BY license ( http://creativecommons.org/licenses/by/4.0/ ). I understand that any comments 
which I do not wish to be included in my named report can be included as confidential comments 
to the editors, which will not be published.  
I agree to the ope n peer review policy of the journal  
Please review this paper.
user
Reviewer ’s report  
Title:  HIGH PREVALENCE OF ADVANCED C OLORECTAL NEOPLASIA IN THE THAI 
POPULATION: A PROSPECTIVE SCREENING COLONOSCOPY OF 1,404 CASE S 
 
Version : 0 Date:  13 Dec 2015  
 
Reviewer : Adam Dziki  
 
Reviewer's report:  
This paper is dealing with an old topic. This may be is new in Thailand. Unfortunately the 
number of patients is small for such analysis. There is also some misunderstanding. In the text  is 
written that the group of patients selected for colonoscopy did not present any symptoms from 
the alimentary tract. In the table there is listed small group of them, which had the symptoms. 
There is a question if in this group there was another finding  that in the other group. There is also 
similar issue. In the text there is written that the patients did not have any family history of CRC 
but in the table there is shown a group of patients with the history of family CRC. There is also 
no information in  this paper if this group of patients had any other findings in the colonoscopy.  
The findings in this paper are well known and there is nothing new in this paper so I leave the 
decision to the Chief -Editor  
 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
Yes 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to  the authors.  
Unable to assess  
  
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
Yes 
Are you able to assess any statistics in the manuscript or would you recommend an 
additional statistica l review?  
If an additional statistical review is recommended, please specify what aspects require further 
assessment in your comments to the editors.  
I am able to assess the statistics  
Quality of written English  
Please indicate the quality of language i n the manuscript:  
Acceptable  
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following questions:  
1. Have you in the past five years received reimbursements, f ees, funding, or salary from an 
organisation that may in any way gain or lose financially from the publi cation of this 
manuscript, either now or in the future?  
2. Do you hold any stocks or shares in an organisation t hat may in any way gain or lose 
financially from the publication of this manuscript, either now or in the future?  
3. Do you hold or are you curr ently applying for any patents  relating to the content of the 
manuscript?  
4. Have you received reimbursements, fees, funding, or salary from an organization that 
holds  or has applied for patents relating to the content of the manuscript?  
5. Do you have any  other financial competing interests?  
6. Do you have any non -financial competing interests in relation to this paper?  
If you can answer no to all of the above, write 'I declare that I have no competing interests' 
below. If your reply is yes to any, please give details below.  
None 
I agree to the open peer review policy of the journal. I understand that my name will be included 
on my report t o the authors and, if the manuscript is accepted for publication, my named report 
including any attachments I upload will be posted on the website along with the authors' 
responses. I agree for my report to be made available under an Open Access Creative C ommons 
CC-BY license ( http://creativecommons.org/licenses/by/4.0/ ). I understand that any comments 
which I do not wish to be included in my named report can be included as confidential comments 
to the editors, which will not be published.  
I agree to the ope n peer review policy of the journal  
assistant