Title: Exploring the Association Between Dietary Fiber Intake and Hepatic Steatosis: Insights
from NHANES
Version: 0 Date: 31 Jan 2024
Reviewer's report:
Comment:
The paper presented analyses the correlation between dietary fibre intake and hepatic steatosis.
The text clearly explains the aim of the study. The methodology applied in the evaluation of
hepatic steatosis is effective for the purpose of the study and the analyses it proposes. The cohort
of patients analysed is large in order to obtain reliable results. Nevertheless, the data on dietary
fibre intake derived from two 24-hour dietary recalls is a major limitation of the study, limiting
its effectiveness. In any case, the study's evaluation is an interesting analysis of fibre's effect on
hepatic steatosis. I suggest acceptance of the manuscript after the following changes.
Major Revisions:
Among the proposed revisions, I suggest expanding the data concerning the demographic
characteristics of the court in the table associated with the study, data such as sex, age and race
are given, but data concerning HDL cholesterol, LDL cholesterol and glycaemia are omitted,
which would be interesting to observe, as well as a clearer analysis of the associated pathologies
other than diabetes and hypertension.
Minor Revisions:
1) I suggest expanding the introductory part of the manuscript with the inclusion of further
information regarding non-alcoholic hepatic steatosis such as the involvement of genetic factors
and microbiota. I suggest the following references: Abenavoli L, Giubilei L, Procopio AC,
Spagnuolo R, Luzza F, Boccuto L, Scarpellini E. Gut Microbiota in Non-Alcoholic Fatty
Liver Disease Patients with Inflammatory Bowel Diseases: A Complex Interplay. Nutrients.
2022 Dec 15;14(24):5323. doi: 10.3390/nu14245323. Elsayed A, Ismaiel A, Procopio AC,
Luzza F, Abenavoli L, Dumitrascu DL.Noninvasive biochemical markers and surrogate
scores in evaluating nonalcoholic steatohepatitis. Minerva Med. 2022 Oct;113(5):864-874.
doi: 10.23736/S0026-4806.22.08185-X. Abenavoli L, Maurizi V, Boccuto L, Di Berardino A,
Giostra N, Santori P, Scarcella ML, Procopio AC, Rasetti C, Scarpellini E. Nutritional Support
in Acute Liver Failure. Diseases. 2022 Nov 18;10(4):108. doi: 10.3390/diseases10040108
Title: Exploring the Association Between Dietary Fiber Intake and Hepatic Steatosis: Insights
from NHANES
Version: 0 Date: 31 Jan 2024
Reviewer's report:
Comment:
The paper presented analyses the correlation between dietary fibre intake and hepatic steatosis.
The text clearly explains the aim of the study. The methodology applied in the evaluation of
hepatic steatosis is effective for the purpose of the study and the analyses it proposes. The cohort
of patients analysed is large in order to obtain reliable results. Nevertheless, the data on dietary
fibre intake derived from two 24-hour dietary recalls is a major limitation of the study, limiting
its effectiveness. In any case, the study's evaluation is an interesting analysis of fibre's effect on
hepatic steatosis. I suggest acceptance of the manuscript after the following changes.
Major Revisions:
Among the proposed revisions, I suggest expanding the data concerning the demographic
characteristics of the court in the table associated with the study, data such as sex, age and race
are given, but data concerning HDL cholesterol, LDL cholesterol and glycaemia are omitted,
which would be interesting to observe, as well as a clearer analysis of the associated pathologies
other than diabetes and hypertension.
Minor Revisions:
1) I suggest expanding the introductory part of the manuscript with the inclusion of further
information regarding non-alcoholic hepatic steatosis such as the involvement of genetic factors
and microbiota. I suggest the following references: Abenavoli L, Giubilei L, Procopio AC,
Spagnuolo R, Luzza F, Boccuto L, Scarpellini E. Gut Microbiota in Non-Alcoholic Fatty
Liver Disease Patients with Inflammatory Bowel Diseases: A Complex Interplay. Nutrients.
2022 Dec 15;14(24):5323. doi: 10.3390/nu14245323. Elsayed A, Ismaiel A, Procopio AC,
Luzza F, Abenavoli L, Dumitrascu DL.Noninvasive biochemical markers and surrogate
scores in evaluating nonalcoholic steatohepatitis. Minerva Med. 2022 Oct;113(5):864-874.
doi: 10.23736/S0026-4806.22.08185-X. Abenavoli L, Maurizi V, Boccuto L, Di Berardino A,
Giostra N, Santori P, Scarcella ML, Procopio AC, Rasetti C, Scarpellini E. Nutritional Support
in Acute Liver Failure. Diseases. 2022 Nov 18;10(4):108. doi: 10.3390/diseases10040108
Please review this paper.
user
Title: Exploring the Association Between Dietary Fiber Intake and Hepatic Steatosis: Insights
from NHANES
Version: 0 Date: 31 Jan 2024
Reviewer's report:
Comment:
The paper presented analyses the correlation between dietary fibre intake and hepatic steatosis.
The text clearly explains the aim of the study. The methodology applied in the evaluation of
hepatic steatosis is effective for the purpose of the study and the analyses it proposes. The cohort
of patients analysed is large in order to obtain reliable results. Nevertheless, the data on dietary
fibre intake derived from two 24-hour dietary recalls is a major limitation of the study, limiting
its effectiveness. In any case, the study's evaluation is an interesting analysis of fibre's effect on
hepatic steatosis. I suggest acceptance of the manuscript after the following changes.
Major Revisions:
Among the proposed revisions, I suggest expanding the data concerning the demographic
characteristics of the court in the table associated with the study, data such as sex, age and race
are given, but data concerning HDL cholesterol, LDL cholesterol and glycaemia are omitted,
which would be interesting to observe, as well as a clearer analysis of the associated pathologies
other than diabetes and hypertension.
Minor Revisions:
1) I suggest expanding the introductory part of the manuscript with the inclusion of further
information regarding non-alcoholic hepatic steatosis such as the involvement of genetic factors
and microbiota. I suggest the following references: Abenavoli L, Giubilei L, Procopio AC,
Spagnuolo R, Luzza F, Boccuto L, Scarpellini E. Gut Microbiota in Non-Alcoholic Fatty
Liver Disease Patients with Inflammatory Bowel Diseases: A Complex Interplay. Nutrients.
2022 Dec 15;14(24):5323. doi: 10.3390/nu14245323. Elsayed A, Ismaiel A, Procopio AC,
Luzza F, Abenavoli L, Dumitrascu DL.Noninvasive biochemical markers and surrogate
scores in evaluating nonalcoholic steatohepatitis. Minerva Med. 2022 Oct;113(5):864-874.
doi: 10.23736/S0026-4806.22.08185-X. Abenavoli L, Maurizi V, Boccuto L, Di Berardino A,
Giostra N, Santori P, Scarcella ML, Procopio AC, Rasetti C, Scarpellini E. Nutritional Support
in Acute Liver Failure. Diseases. 2022 Nov 18;10(4):108. doi: 10.3390/diseases10040108
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