Title: Comprehensive analysis of ferroptosis-related long non-coding RNA and its
association with tumor progression and ferroptosis in gastric cancer
Version: 1 Date: 25 Jan 2025
Reviewer:  Dimitrios Kehagias
Reviewer's report:
Thank you for the opportunity to review this well-written and presented manuscript. The
structure and methods are clear, enabling reproducibility, while the model is correctly
constructed. The authors well acknowledge the limitations. Below are only some minor
comments for the authors:
1. Have you assessed the type of gastric cancer? For instance if it is diffuse type with signet ring
or an intestinal type? Can this affect the RNAs and mRNAS?
2. Regarding patient characteristics, you mention the stage but we do not have information
regarding neoadjuvant treatment which again might affect ferroptosis.
Title: Comprehensive analysis of ferroptosis-related long non-coding RNA and its
association with tumor progression and ferroptosis in gastric cancer
Version: 1 Date: 25 Jan 2025
Reviewer:  Dimitrios Kehagias
Reviewer's report:
Thank you for the opportunity to review this well-written and presented manuscript. The
structure and methods are clear, enabling reproducibility, while the model is correctly
constructed. The authors well acknowledge the limitations. Below are only some minor
comments for the authors:
1. Have you assessed the type of gastric cancer? For instance if it is diffuse type with signet ring
or an intestinal type? Can this affect the RNAs and mRNAS?
2. Regarding patient characteristics, you mention the stage but we do not have information
regarding neoadjuvant treatment which again might affect ferroptosis.
Please review this paper.
user
Title: Comprehensive analysis of ferroptosis-related long non-coding RNA and its
association with tumor progression and ferroptosis in gastric cancer
Version: 1 Date: 25 Jan 2025
Reviewer:  Dimitrios Kehagias
Reviewer's report:
Thank you for the opportunity to review this well-written and presented manuscript. The
structure and methods are clear, enabling reproducibility, while the model is correctly
constructed. The authors well acknowledge the limitations. Below are only some minor
comments for the authors:
1. Have you assessed the type of gastric cancer? For instance if it is diffuse type with signet ring
or an intestinal type? Can this affect the RNAs and mRNAS?
2. Regarding patient characteristics, you mention the stage but we do not have information
regarding neoadjuvant treatment which again might affect ferroptosis.
assistant