Title: Comparison of vonoprazan and proton pump inhibitors for the treatment of gastric
endoscopic submucosal dissection-induced ulcer: An updated systematic review and meta-
analysis
Version: 1 Date: 04 Jan 2024
Reviewer's report:
Chen et al. conducted a sophisticated systematic review on post-ESD bleeding, highlighting the
superiority of vonoprazan over PPIs. The manuscript is well-written and informative.
1. It would be beneficial to address the potential influence of the gastric lesion's location
on delayed bleeding. If this information is available in the RCTs analyzed, please provide
clarification.
2. Considering the impact of the endoscopic knife type on delayed bleeding rates is crucial. If
feasible, please include details regarding the types of endoscopic knives used in the studies.
Title: Comparison of vonoprazan and proton pump inhibitors for the treatment of gastric
endoscopic submucosal dissection-induced ulcer: An updated systematic review and meta-
analysis
Version: 1 Date: 04 Jan 2024
Reviewer's report:
Chen et al. conducted a sophisticated systematic review on post-ESD bleeding, highlighting the
superiority of vonoprazan over PPIs. The manuscript is well-written and informative.
1. It would be beneficial to address the potential influence of the gastric lesion's location
on delayed bleeding. If this information is available in the RCTs analyzed, please provide
clarification.
2. Considering the impact of the endoscopic knife type on delayed bleeding rates is crucial. If
feasible, please include details regarding the types of endoscopic knives used in the studies.
Please review this paper.
user
Title: Comparison of vonoprazan and proton pump inhibitors for the treatment of gastric
endoscopic submucosal dissection-induced ulcer: An updated systematic review and meta-
analysis
Version: 1 Date: 04 Jan 2024
Reviewer's report:
Chen et al. conducted a sophisticated systematic review on post-ESD bleeding, highlighting the
superiority of vonoprazan over PPIs. The manuscript is well-written and informative.
1. It would be beneficial to address the potential influence of the gastric lesion's location
on delayed bleeding. If this information is available in the RCTs analyzed, please provide
clarification.
2. Considering the impact of the endoscopic knife type on delayed bleeding rates is crucial. If
feasible, please include details regarding the types of endoscopic knives used in the studies.
assistant