Title: Effects of a 12-week home-based exercise training program on aerobic capacity, muscle
mass, liver and spleen stiffness, and quality of life in cirrhotic patients: A randomized controlled
clinical trial
Version: 2 Date: 26 Nov 2021
Reviewer:  Gopal Nambi
Reviewer's report:
1. Mention who has diagnosed the condition and is included in the trial?
2. 60 – 80 % of MHR is considered as high-intensity aerobic training – please correct the level
of training.
3. Include the blinding details of the study.
4. In the results section, please discuss about the treatment compliance rate, adverse effects, and
the number of dropouts.
5. In the discussion, indicate MCID for the primary outcome and explain it.
6. Table 1 – did not include any aerobic exercises also the exercises which mentioned in table
1 do not come under isometric exercises – The authors must justify this part in clear because
this is the core part of the study.
7. Include a detailed description of all exercises and their parameters with suitable figures.
Title: Effects of a 12-week home-based exercise training program on aerobic capacity, muscle
mass, liver and spleen stiffness, and quality of life in cirrhotic patients: A randomized controlled
clinical trial
Version: 2 Date: 26 Nov 2021
Reviewer:  Gopal Nambi
Reviewer's report:
1. Mention who has diagnosed the condition and is included in the trial?
2. 60 – 80 % of MHR is considered as high-intensity aerobic training – please correct the level
of training.
3. Include the blinding details of the study.
4. In the results section, please discuss about the treatment compliance rate, adverse effects, and
the number of dropouts.
5. In the discussion, indicate MCID for the primary outcome and explain it.
6. Table 1 – did not include any aerobic exercises also the exercises which mentioned in table
1 do not come under isometric exercises – The authors must justify this part in clear because
this is the core part of the study.
7. Include a detailed description of all exercises and their parameters with suitable figures.
Please review this paper.
user
Title: Effects of a 12-week home-based exercise training program on aerobic capacity, muscle
mass, liver and spleen stiffness, and quality of life in cirrhotic patients: A randomized controlled
clinical trial
Version: 2 Date: 26 Nov 2021
Reviewer:  Gopal Nambi
Reviewer's report:
1. Mention who has diagnosed the condition and is included in the trial?
2. 60 – 80 % of MHR is considered as high-intensity aerobic training – please correct the level
of training.
3. Include the blinding details of the study.
4. In the results section, please discuss about the treatment compliance rate, adverse effects, and
the number of dropouts.
5. In the discussion, indicate MCID for the primary outcome and explain it.
6. Table 1 – did not include any aerobic exercises also the exercises which mentioned in table
1 do not come under isometric exercises – The authors must justify this part in clear because
this is the core part of the study.
7. Include a detailed description of all exercises and their parameters with suitable figures.
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