Title: Predictive Model for Identification of Gangrenous or Perforated Appendicitis in Adults:
A Multicenter Retrospective Study
Version: 7 Date: 21 Aug 2024
Reviewer:  Florin Iordache
Reviewer's report:
Dear authors,
You did a good job revising the manuscript but you did not answer /explain the following:
Why exclude patients aged over 65? In some studies, it is a risk factor for complicated
appendicitis. Furthermore, the study of Eddama et al. (cited by the authors - ref. 13) validates
age. In the reviewed paper there were 13 patients excluded. This is an important study bias -
please address it.
Title: Predictive Model for Identification of Gangrenous or Perforated Appendicitis in Adults:
A Multicenter Retrospective Study
Version: 7 Date: 21 Aug 2024
Reviewer:  Florin Iordache
Reviewer's report:
Dear authors,
You did a good job revising the manuscript but you did not answer /explain the following:
Why exclude patients aged over 65? In some studies, it is a risk factor for complicated
appendicitis. Furthermore, the study of Eddama et al. (cited by the authors - ref. 13) validates
age. In the reviewed paper there were 13 patients excluded. This is an important study bias -
please address it.
Please review this paper.
user
Title: Predictive Model for Identification of Gangrenous or Perforated Appendicitis in Adults:
A Multicenter Retrospective Study
Version: 7 Date: 21 Aug 2024
Reviewer:  Florin Iordache
Reviewer's report:
Dear authors,
You did a good job revising the manuscript but you did not answer /explain the following:
Why exclude patients aged over 65? In some studies, it is a risk factor for complicated
appendicitis. Furthermore, the study of Eddama et al. (cited by the authors - ref. 13) validates
age. In the reviewed paper there were 13 patients excluded. This is an important study bias -
please address it.
assistant