Title: Analysis of the distribution characteristics of pathogenic bacteria in the wound tissue of
patients with perianal abscess combined with infection and the influencing factors of wound
healing
Version: 2 Date: 16 Dec 2024
Reviewer:  Reza Ghotaslou
Reviewer's report:
1. "200 patients with perianal abscess combined with infection admitted to our hosp" The number
should be converted into letters, for example, two hundred.
2. The English language has many problems and it is better to be corrected by an expert.
3. gram-negative is not correct.
4. Escherichia coli and Klebsiella pneumoniae must be italicized.
5. The conclusion is not informative.
6. Have all the patients been operated on by one surgeon? If the answer to this question is NO,
the study conditions differ, and the surgeon's expertise is significant.
7. Obligate anaerobic pathogenic bacteria are very important in abscesses, especially in the anus
area. Laboratory conditions show that such bacteria have not been studied. Please clarify why.
8. Many background diseases play a role in this matter, which have not been taken into account.
9. The contamination during sampling is very important, especially in this area. The measures
taken to prevent contamination are not enough.
10.  Delete Table 1.
11. There are three diagrams in photo number one. Please turn it into a diagram.
12. " tumour" what does mean?
13. Delete Fig. 2
14. The relationship between the pathogen and underlying disease has not been determined.
15.  Have the occupations of the patients been studied?
16.  The conditions for entering the study were not the same for everyone, and the conditions of
withdrawal from the study were not written. Inclusion and exclusion criteria.
Title: Analysis of the distribution characteristics of pathogenic bacteria in the wound tissue of
patients with perianal abscess combined with infection and the influencing factors of wound
healing
Version: 2 Date: 16 Dec 2024
Reviewer:  Reza Ghotaslou
Reviewer's report:
1. "200 patients with perianal abscess combined with infection admitted to our hosp" The number
should be converted into letters, for example, two hundred.
2. The English language has many problems and it is better to be corrected by an expert.
3. gram-negative is not correct.
4. Escherichia coli and Klebsiella pneumoniae must be italicized.
5. The conclusion is not informative.
6. Have all the patients been operated on by one surgeon? If the answer to this question is NO,
the study conditions differ, and the surgeon's expertise is significant.
7. Obligate anaerobic pathogenic bacteria are very important in abscesses, especially in the anus
area. Laboratory conditions show that such bacteria have not been studied. Please clarify why.
8. Many background diseases play a role in this matter, which have not been taken into account.
9. The contamination during sampling is very important, especially in this area. The measures
taken to prevent contamination are not enough.
10.  Delete Table 1.
11. There are three diagrams in photo number one. Please turn it into a diagram.
12. " tumour" what does mean?
13. Delete Fig. 2
14. The relationship between the pathogen and underlying disease has not been determined.
15.  Have the occupations of the patients been studied?
16.  The conditions for entering the study were not the same for everyone, and the conditions of
withdrawal from the study were not written. Inclusion and exclusion criteria.
Please review this paper.
user
Title: Analysis of the distribution characteristics of pathogenic bacteria in the wound tissue of
patients with perianal abscess combined with infection and the influencing factors of wound
healing
Version: 2 Date: 16 Dec 2024
Reviewer:  Reza Ghotaslou
Reviewer's report:
1. "200 patients with perianal abscess combined with infection admitted to our hosp" The number
should be converted into letters, for example, two hundred.
2. The English language has many problems and it is better to be corrected by an expert.
3. gram-negative is not correct.
4. Escherichia coli and Klebsiella pneumoniae must be italicized.
5. The conclusion is not informative.
6. Have all the patients been operated on by one surgeon? If the answer to this question is NO,
the study conditions differ, and the surgeon's expertise is significant.
7. Obligate anaerobic pathogenic bacteria are very important in abscesses, especially in the anus
area. Laboratory conditions show that such bacteria have not been studied. Please clarify why.
8. Many background diseases play a role in this matter, which have not been taken into account.
9. The contamination during sampling is very important, especially in this area. The measures
taken to prevent contamination are not enough.
10.  Delete Table 1.
11. There are three diagrams in photo number one. Please turn it into a diagram.
12. " tumour" what does mean?
13. Delete Fig. 2
14. The relationship between the pathogen and underlying disease has not been determined.
15.  Have the occupations of the patients been studied?
16.  The conditions for entering the study were not the same for everyone, and the conditions of
withdrawal from the study were not written. Inclusion and exclusion criteria.
assistant