Title: Evaluation of Double-Balloon Enteroscopy in the Management of Type 1 Small Bowel
Vascular Lesions (angioectasia): A Retrospective Cohort Study
Version: 3 Date: 25 Nov 2024
Reviewer's report:
Dear authors,
Thanks for your responses
Although some limitations in your manuscript as the following:
Retrospective Design: As a retrospective single-center study, the results may not be
generalizable to broader populations. A multi-center, prospective study would improve the
robustness of the conclusions.
Small Sample Size: The relatively small sample size (67 patients with SBVL) limits the strength
and statistical power of the findings, especially in subgroup analyses.
Lack of Standardized Treatment Protocol: The variability in the choice of treatment techniques
(e.g., APC, injection therapy, clipping) based on the endoscopist's discretion introduces some
variability that could affect the consistency and comparability of the results.
Follow-up Variability: The variability in follow-up duration may impact the observed rebleeding
rates. A standardized follow-up period across patients would provide a more accurate assessment
of long-term outcomes.
But, this study makes a significant contribution to the understanding of SBVLs and the role
of DBE in their management. While the study has its limitations, its findings are valuable for
guiding clinical practice, particularly in predicting rebleeding risk and tailoring patient care. The
authors' use of a structured classification system and their analysis of clinical predictors offer
important insights that can enhance the management of patients with small bowel bleeding.
Title: Evaluation of Double-Balloon Enteroscopy in the Management of Type 1 Small Bowel
Vascular Lesions (angioectasia): A Retrospective Cohort Study
Version: 3 Date: 25 Nov 2024
Reviewer's report:
Dear authors,
Thanks for your responses
Although some limitations in your manuscript as the following:
Retrospective Design: As a retrospective single-center study, the results may not be
generalizable to broader populations. A multi-center, prospective study would improve the
robustness of the conclusions.
Small Sample Size: The relatively small sample size (67 patients with SBVL) limits the strength
and statistical power of the findings, especially in subgroup analyses.
Lack of Standardized Treatment Protocol: The variability in the choice of treatment techniques
(e.g., APC, injection therapy, clipping) based on the endoscopist's discretion introduces some
variability that could affect the consistency and comparability of the results.
Follow-up Variability: The variability in follow-up duration may impact the observed rebleeding
rates. A standardized follow-up period across patients would provide a more accurate assessment
of long-term outcomes.
But, this study makes a significant contribution to the understanding of SBVLs and the role
of DBE in their management. While the study has its limitations, its findings are valuable for
guiding clinical practice, particularly in predicting rebleeding risk and tailoring patient care. The
authors' use of a structured classification system and their analysis of clinical predictors offer
important insights that can enhance the management of patients with small bowel bleeding.
Please review this paper.
user
Title: Evaluation of Double-Balloon Enteroscopy in the Management of Type 1 Small Bowel
Vascular Lesions (angioectasia): A Retrospective Cohort Study
Version: 3 Date: 25 Nov 2024
Reviewer's report:
Dear authors,
Thanks for your responses
Although some limitations in your manuscript as the following:
Retrospective Design: As a retrospective single-center study, the results may not be
generalizable to broader populations. A multi-center, prospective study would improve the
robustness of the conclusions.
Small Sample Size: The relatively small sample size (67 patients with SBVL) limits the strength
and statistical power of the findings, especially in subgroup analyses.
Lack of Standardized Treatment Protocol: The variability in the choice of treatment techniques
(e.g., APC, injection therapy, clipping) based on the endoscopist's discretion introduces some
variability that could affect the consistency and comparability of the results.
Follow-up Variability: The variability in follow-up duration may impact the observed rebleeding
rates. A standardized follow-up period across patients would provide a more accurate assessment
of long-term outcomes.
But, this study makes a significant contribution to the understanding of SBVLs and the role
of DBE in their management. While the study has its limitations, its findings are valuable for
guiding clinical practice, particularly in predicting rebleeding risk and tailoring patient care. The
authors' use of a structured classification system and their analysis of clinical predictors offer
important insights that can enhance the management of patients with small bowel bleeding.
assistant