Title: The Newly Proposed Plasma-Glycosylated Hemoglobin A1c/High-Density Lipoprotein
Cholesterol Ratio Serves as A Simple and Practical Indicator for Screening Metabolic
Associated Fatty Liver Disease: An Observational Study Based on A Physical Examination
Population
Version: 2 Date: 15 Jul 2024
Reviewer:  Mustafa Cesur
Reviewer's report:
The authors tried to find a new  practical indicator for screening metabolic associated fatty
liver disease (MAFLD). But they haven't mentioned any cut off number. They showed only
relationship of HbA1c and HDL ratio with MAFLD. There is no cut off value, there is only
correlation. So the ratio can not be an indicator.
I suggest to make a correlation HbA1c and HDL ratio to FIB-4 scores of the subjects, and to
have  a value as an indicator. This will improve the study.
Moreover the result part is not clear. Especially the quartils neeed wide definition. To make a
quartil (Q) definiton is better.
Title: The Newly Proposed Plasma-Glycosylated Hemoglobin A1c/High-Density Lipoprotein
Cholesterol Ratio Serves as A Simple and Practical Indicator for Screening Metabolic
Associated Fatty Liver Disease: An Observational Study Based on A Physical Examination
Population
Version: 2 Date: 15 Jul 2024
Reviewer:  Mustafa Cesur
Reviewer's report:
The authors tried to find a new  practical indicator for screening metabolic associated fatty
liver disease (MAFLD). But they haven't mentioned any cut off number. They showed only
relationship of HbA1c and HDL ratio with MAFLD. There is no cut off value, there is only
correlation. So the ratio can not be an indicator.
I suggest to make a correlation HbA1c and HDL ratio to FIB-4 scores of the subjects, and to
have  a value as an indicator. This will improve the study.
Moreover the result part is not clear. Especially the quartils neeed wide definition. To make a
quartil (Q) definiton is better.
Please review this paper.
user
Title: The Newly Proposed Plasma-Glycosylated Hemoglobin A1c/High-Density Lipoprotein
Cholesterol Ratio Serves as A Simple and Practical Indicator for Screening Metabolic
Associated Fatty Liver Disease: An Observational Study Based on A Physical Examination
Population
Version: 2 Date: 15 Jul 2024
Reviewer:  Mustafa Cesur
Reviewer's report:
The authors tried to find a new  practical indicator for screening metabolic associated fatty
liver disease (MAFLD). But they haven't mentioned any cut off number. They showed only
relationship of HbA1c and HDL ratio with MAFLD. There is no cut off value, there is only
correlation. So the ratio can not be an indicator.
I suggest to make a correlation HbA1c and HDL ratio to FIB-4 scores of the subjects, and to
have  a value as an indicator. This will improve the study.
Moreover the result part is not clear. Especially the quartils neeed wide definition. To make a
quartil (Q) definiton is better.
assistant