Reviewer’s report 
Title:  Case report: Successful resection of a leiomyoma c ausing pseudoachalasia at the 
esophagogastric junction by tunnel endoscopy 
 
Version : 0 Date:  29 Dec 2015 
 
Reviewer:  Shiro Oka 
 
Reviewer's report: 
I reviewed with the interest article entitled "Succ essful resection of a leiomyoma causing 
pseudoachalasia at the esophagogastric junction by tunnel endoscopy". In this report, the authors 
presented a rare case of esophageal leiomyoma that was initially diagnosed with achalasia. The 
case was diagnosed pseudoachalasia among endoscopic  treatment, and successfully treated 
through submucosal tunneling endoscopic resection. This case is interesting, however, but I do 
think some issues should be clarified. 
 
My suggestions are as follows: 
1. Did you perform EUS in this case? Please comment  in detail. In discussion part, you 
recommended that EUS is useful to distinguish betwe en achalasia and pseudoachalasia. 
2. I think that endoscopic finding is important for  achalasia diagnosis. You should mention 
endoscopic finding in case presentation. 
 
Are the methods appropriate and well described? 
If not, please specify what is required in your com ments to the authors. 
Yes 
Does the work include the necessary controls? 
If not, please specify which controls are required in your comments to the authors. 
Yes 
Are the conclusions drawn adequately supported by t he data shown? 
If not, please explain in your comments to the auth ors. 
Yes 
Are you able to assess any statistics in the manusc ript or would you recommend an 
additional statistical review? 
If an additional statistical review is recommended,  please specify what aspects require further 
assessment in your comments to the editors. 
I recommend additional statistical review 
Quality of written English 
Please indicate the quality of language in the manu script: 
Acceptable 
Declaration of competing interests 
Please complete a declaration of competing interest s, considering the following questions: 
1. Have you in the past five years received reimbur sements, fees, funding, or salary from an 
organisation that may in any way gain or lose finan cially from the publication of this 
manuscript, either now or in the future? 
2. Do you hold any stocks or shares in an organisat ion that may in any way gain or lose 
financially from the publication of this manuscript , either now or in the future? 
3. Do you hold or are you currently applying for an y patents relating to the content of the 
manuscript? 
4. Have you received reimbursements, fees, funding,  or salary from an organization that holds 
or has applied for patents relating to the content of the manuscript? 
5. Do you have any other financial competing intere sts? 
6. Do you have any non-financial competing interest s in relation to this paper? 
If you can answer no to all of the above, write 'I declare that I have no competing interests' 
below. If your reply is yes to any, please give det ails below. 
I declare that I have no competing interests 
I agree to the open peer review policy of the journ al. I understand that my name will be included 
on my report to the authors and, if the manuscript is accepted for publication, my named report 
including any attachments I upload will be posted o n the website along with the authors' 
responses. I agree for my report to be made availab le under an Open Access Creative Commons 
CC-BY license (http://creativecommons.org/licenses/ by/4.0/). I understand that any comments 
which I do not wish to be included in my named repo rt can be included as confidential comments 
to the editors, which will not be published. 
I agree to the open peer review policy of the journ al 
Reviewer’s report 
Title:  Case report: Successful resection of a leiomyoma c ausing pseudoachalasia at the 
esophagogastric junction by tunnel endoscopy 
 
Version : 0 Date:  29 Dec 2015 
 
Reviewer:  Shiro Oka 
 
Reviewer's report: 
I reviewed with the interest article entitled "Succ essful resection of a leiomyoma causing 
pseudoachalasia at the esophagogastric junction by tunnel endoscopy". In this report, the authors 
presented a rare case of esophageal leiomyoma that was initially diagnosed with achalasia. The 
case was diagnosed pseudoachalasia among endoscopic  treatment, and successfully treated 
through submucosal tunneling endoscopic resection. This case is interesting, however, but I do 
think some issues should be clarified. 
 
My suggestions are as follows: 
1. Did you perform EUS in this case? Please comment  in detail. In discussion part, you 
recommended that EUS is useful to distinguish betwe en achalasia and pseudoachalasia. 
2. I think that endoscopic finding is important for  achalasia diagnosis. You should mention 
endoscopic finding in case presentation. 
 
Are the methods appropriate and well described? 
If not, please specify what is required in your com ments to the authors. 
Yes 
Does the work include the necessary controls? 
If not, please specify which controls are required in your comments to the authors. 
Yes 
Are the conclusions drawn adequately supported by t he data shown? 
If not, please explain in your comments to the auth ors. 
Yes 
Are you able to assess any statistics in the manusc ript or would you recommend an 
additional statistical review? 
If an additional statistical review is recommended,  please specify what aspects require further 
assessment in your comments to the editors. 
I recommend additional statistical review 
Quality of written English 
Please indicate the quality of language in the manu script: 
Acceptable 
Declaration of competing interests 
Please complete a declaration of competing interest s, considering the following questions: 
1. Have you in the past five years received reimbur sements, fees, funding, or salary from an 
organisation that may in any way gain or lose finan cially from the publication of this 
manuscript, either now or in the future? 
2. Do you hold any stocks or shares in an organisat ion that may in any way gain or lose 
financially from the publication of this manuscript , either now or in the future? 
3. Do you hold or are you currently applying for an y patents relating to the content of the 
manuscript? 
4. Have you received reimbursements, fees, funding,  or salary from an organization that holds 
or has applied for patents relating to the content of the manuscript? 
5. Do you have any other financial competing intere sts? 
6. Do you have any non-financial competing interest s in relation to this paper? 
If you can answer no to all of the above, write 'I declare that I have no competing interests' 
below. If your reply is yes to any, please give det ails below. 
I declare that I have no competing interests 
I agree to the open peer review policy of the journ al. I understand that my name will be included 
on my report to the authors and, if the manuscript is accepted for publication, my named report 
including any attachments I upload will be posted o n the website along with the authors' 
responses. I agree for my report to be made availab le under an Open Access Creative Commons 
CC-BY license (http://creativecommons.org/licenses/ by/4.0/). I understand that any comments 
which I do not wish to be included in my named repo rt can be included as confidential comments 
to the editors, which will not be published. 
I agree to the open peer review policy of the journ al 
Please review this paper.
user
Reviewer’s report 
Title:  Case report: Successful resection of a leiomyoma c ausing pseudoachalasia at the 
esophagogastric junction by tunnel endoscopy 
 
Version : 0 Date:  29 Dec 2015 
 
Reviewer:  Shiro Oka 
 
Reviewer's report: 
I reviewed with the interest article entitled "Succ essful resection of a leiomyoma causing 
pseudoachalasia at the esophagogastric junction by tunnel endoscopy". In this report, the authors 
presented a rare case of esophageal leiomyoma that was initially diagnosed with achalasia. The 
case was diagnosed pseudoachalasia among endoscopic  treatment, and successfully treated 
through submucosal tunneling endoscopic resection. This case is interesting, however, but I do 
think some issues should be clarified. 
 
My suggestions are as follows: 
1. Did you perform EUS in this case? Please comment  in detail. In discussion part, you 
recommended that EUS is useful to distinguish betwe en achalasia and pseudoachalasia. 
2. I think that endoscopic finding is important for  achalasia diagnosis. You should mention 
endoscopic finding in case presentation. 
 
Are the methods appropriate and well described? 
If not, please specify what is required in your com ments to the authors. 
Yes 
Does the work include the necessary controls? 
If not, please specify which controls are required in your comments to the authors. 
Yes 
Are the conclusions drawn adequately supported by t he data shown? 
If not, please explain in your comments to the auth ors. 
Yes 
Are you able to assess any statistics in the manusc ript or would you recommend an 
additional statistical review? 
If an additional statistical review is recommended,  please specify what aspects require further 
assessment in your comments to the editors. 
I recommend additional statistical review 
Quality of written English 
Please indicate the quality of language in the manu script: 
Acceptable 
Declaration of competing interests 
Please complete a declaration of competing interest s, considering the following questions: 
1. Have you in the past five years received reimbur sements, fees, funding, or salary from an 
organisation that may in any way gain or lose finan cially from the publication of this 
manuscript, either now or in the future? 
2. Do you hold any stocks or shares in an organisat ion that may in any way gain or lose 
financially from the publication of this manuscript , either now or in the future? 
3. Do you hold or are you currently applying for an y patents relating to the content of the 
manuscript? 
4. Have you received reimbursements, fees, funding,  or salary from an organization that holds 
or has applied for patents relating to the content of the manuscript? 
5. Do you have any other financial competing intere sts? 
6. Do you have any non-financial competing interest s in relation to this paper? 
If you can answer no to all of the above, write 'I declare that I have no competing interests' 
below. If your reply is yes to any, please give det ails below. 
I declare that I have no competing interests 
I agree to the open peer review policy of the journ al. I understand that my name will be included 
on my report to the authors and, if the manuscript is accepted for publication, my named report 
including any attachments I upload will be posted o n the website along with the authors' 
responses. I agree for my report to be made availab le under an Open Access Creative Commons 
CC-BY license (http://creativecommons.org/licenses/ by/4.0/). I understand that any comments 
which I do not wish to be included in my named repo rt can be included as confidential comments 
to the editors, which will not be published. 
I agree to the open peer review policy of the journ al 
assistant