Title: Fatigue, pain and faecal incontinence in adult Inflammatory Bowel Disease patients and
the unmet need: a national cross-sectional survey
Version: 2 Date: 01 Nov 2024
Reviewer's report:
This is a well intended study addressing as mentioned un met needs in the realm of IBD. The
manuscript did a great job in approaching a large cohort of patients and in obtaining a greater
sample size.
Some of comments on the study:
1. While addressing some of the key symptoms of fatigue, pain and fecal incontinence the  group
may have missed exploring other unmet features of loss of work,  socioeconomic impacts and
limitation to social life and so on.
2. While the presence or absence of the symptoms in past 7 days do provide with some insight
many of these patients do have prolonged disease with variable days of symptomatology
3. The scoring system used may work for pain but do not appear to be valid for fatigue or fecal
incontinence. This may  also shed doubts on correlation being concluded between these variables
4. As acknowledged this study is vary much affected by reporting bias
Overall the study sheds light on clinically relevant unmet needs in IBD and also on patients
requesting for aid for these issues.
Title: Fatigue, pain and faecal incontinence in adult Inflammatory Bowel Disease patients and
the unmet need: a national cross-sectional survey
Version: 2 Date: 01 Nov 2024
Reviewer's report:
This is a well intended study addressing as mentioned un met needs in the realm of IBD. The
manuscript did a great job in approaching a large cohort of patients and in obtaining a greater
sample size.
Some of comments on the study:
1. While addressing some of the key symptoms of fatigue, pain and fecal incontinence the  group
may have missed exploring other unmet features of loss of work,  socioeconomic impacts and
limitation to social life and so on.
2. While the presence or absence of the symptoms in past 7 days do provide with some insight
many of these patients do have prolonged disease with variable days of symptomatology
3. The scoring system used may work for pain but do not appear to be valid for fatigue or fecal
incontinence. This may  also shed doubts on correlation being concluded between these variables
4. As acknowledged this study is vary much affected by reporting bias
Overall the study sheds light on clinically relevant unmet needs in IBD and also on patients
requesting for aid for these issues.
Please review this paper.
user
Title: Fatigue, pain and faecal incontinence in adult Inflammatory Bowel Disease patients and
the unmet need: a national cross-sectional survey
Version: 2 Date: 01 Nov 2024
Reviewer's report:
This is a well intended study addressing as mentioned un met needs in the realm of IBD. The
manuscript did a great job in approaching a large cohort of patients and in obtaining a greater
sample size.
Some of comments on the study:
1. While addressing some of the key symptoms of fatigue, pain and fecal incontinence the  group
may have missed exploring other unmet features of loss of work,  socioeconomic impacts and
limitation to social life and so on.
2. While the presence or absence of the symptoms in past 7 days do provide with some insight
many of these patients do have prolonged disease with variable days of symptomatology
3. The scoring system used may work for pain but do not appear to be valid for fatigue or fecal
incontinence. This may  also shed doubts on correlation being concluded between these variables
4. As acknowledged this study is vary much affected by reporting bias
Overall the study sheds light on clinically relevant unmet needs in IBD and also on patients
requesting for aid for these issues.
assistant