Title: Changes in microbial and metabolic profiles of mice fed with long-term high salt diet
Version: 2 Date: 01 Aug 2024
Reviewer's report:
In this study, the authors investigated the changes in microbial and metabolic profiles of mice fed
with long-term high salt diet. Generally, the study was well designed and the results are good.
Revisions are recommended for further publication.
(1) In the results section, the authors just described the composition of gut microbiota,
metabolites and their associations. They did not provide any verification results. It will be very
good if they provide RT-PCR results or germ-free mice to confirm the bacteria to be interested.
(2) What are the innovations in this study compared with previous studies? Please describe it
somewhere in the text.
Title: Changes in microbial and metabolic profiles of mice fed with long-term high salt diet
Version: 2 Date: 01 Aug 2024
Reviewer's report:
In this study, the authors investigated the changes in microbial and metabolic profiles of mice fed
with long-term high salt diet. Generally, the study was well designed and the results are good.
Revisions are recommended for further publication.
(1) In the results section, the authors just described the composition of gut microbiota,
metabolites and their associations. They did not provide any verification results. It will be very
good if they provide RT-PCR results or germ-free mice to confirm the bacteria to be interested.
(2) What are the innovations in this study compared with previous studies? Please describe it
somewhere in the text.
Please review this paper.
user
Title: Changes in microbial and metabolic profiles of mice fed with long-term high salt diet
Version: 2 Date: 01 Aug 2024
Reviewer's report:
In this study, the authors investigated the changes in microbial and metabolic profiles of mice fed
with long-term high salt diet. Generally, the study was well designed and the results are good.
Revisions are recommended for further publication.
(1) In the results section, the authors just described the composition of gut microbiota,
metabolites and their associations. They did not provide any verification results. It will be very
good if they provide RT-PCR results or germ-free mice to confirm the bacteria to be interested.
(2) What are the innovations in this study compared with previous studies? Please describe it
somewhere in the text.
assistant