Title: Association between gastrointestinal disorders and sleep-related problems: the mediating
effect of depression
Version: 6 Date: 16 Jul 2025
Reviewer's report:
Thank you for your thoughtful and comprehensive revisions. I appreciate the clear and
constructive manner in which you addressed all reviewer comments.
The modifications made to terminology—particularly the consistent use of terms like
"association" and "increased probability" to reflect the cross-sectional study design—are
appropriate and enhance the manuscript’s clarity.
The added clarifications regarding gastrointestinal and sleep variable limitations are well-
articulated and meet the expectations for transparency in methodology and discussion. The
inclusion of unmeasured confounders, such as sleep apnea and chronic pain, strengthens the
study's acknowledgment of its limitations.
The reorganization of Table 1 with subheadings and the provision of a concise version in the
main text, along with high-quality figure files, significantly improves the overall readability and
presentation.
Additionally, the adjustments to formatting consistency and contact information are
appropriately handled.
Overall, the manuscript is much improved and now meets the standards required for publication.
I commend the authors for their diligence in responding to feedback and improving the
manuscript.
No further revisions are necessary.
Title: Association between gastrointestinal disorders and sleep-related problems: the mediating
effect of depression
Version: 6 Date: 16 Jul 2025
Reviewer's report:
Thank you for your thoughtful and comprehensive revisions. I appreciate the clear and
constructive manner in which you addressed all reviewer comments.
The modifications made to terminology—particularly the consistent use of terms like
"association" and "increased probability" to reflect the cross-sectional study design—are
appropriate and enhance the manuscript’s clarity.
The added clarifications regarding gastrointestinal and sleep variable limitations are well-
articulated and meet the expectations for transparency in methodology and discussion. The
inclusion of unmeasured confounders, such as sleep apnea and chronic pain, strengthens the
study's acknowledgment of its limitations.
The reorganization of Table 1 with subheadings and the provision of a concise version in the
main text, along with high-quality figure files, significantly improves the overall readability and
presentation.
Additionally, the adjustments to formatting consistency and contact information are
appropriately handled.
Overall, the manuscript is much improved and now meets the standards required for publication.
I commend the authors for their diligence in responding to feedback and improving the
manuscript.
No further revisions are necessary.
Please review this paper.
user
Title: Association between gastrointestinal disorders and sleep-related problems: the mediating
effect of depression
Version: 6 Date: 16 Jul 2025
Reviewer's report:
Thank you for your thoughtful and comprehensive revisions. I appreciate the clear and
constructive manner in which you addressed all reviewer comments.
The modifications made to terminology—particularly the consistent use of terms like
"association" and "increased probability" to reflect the cross-sectional study design—are
appropriate and enhance the manuscript’s clarity.
The added clarifications regarding gastrointestinal and sleep variable limitations are well-
articulated and meet the expectations for transparency in methodology and discussion. The
inclusion of unmeasured confounders, such as sleep apnea and chronic pain, strengthens the
study's acknowledgment of its limitations.
The reorganization of Table 1 with subheadings and the provision of a concise version in the
main text, along with high-quality figure files, significantly improves the overall readability and
presentation.
Additionally, the adjustments to formatting consistency and contact information are
appropriately handled.
Overall, the manuscript is much improved and now meets the standards required for publication.
I commend the authors for their diligence in responding to feedback and improving the
manuscript.
No further revisions are necessary.
assistant