Title: Outcomes of endoscopic submucosal dissection for gastroesophageal reflux disease
(ESD-G) for medication-refractory gastroesophageal reflux disease: 35 cases underwent ESD-
G including 15 cases followed more than 5 years.
Version: 5 Date: 21 Oct 2021
Reviewer:  Shiko Kuribayashi
Reviewer's report:
Authors answered my questions; however, their answers were not enough.
Major comments
1. How did you recognize location of the EGJ? X-ray could not help to recognize the location
of the EGJ. HRM was performed in all patients? Data regarding HRM (diagnoses of esophageal
motility) and impedance-pH monitoring (number of acid and non-acid reflux events and
relationship between symptom and reflux event) should be shown in Table 1. Although there
were several limitations in the study, these data can be shown according to your explanation.
This is very important to understand indications of ESD-G.
Title: Outcomes of endoscopic submucosal dissection for gastroesophageal reflux disease
(ESD-G) for medication-refractory gastroesophageal reflux disease: 35 cases underwent ESD-
G including 15 cases followed more than 5 years.
Version: 5 Date: 21 Oct 2021
Reviewer:  Shiko Kuribayashi
Reviewer's report:
Authors answered my questions; however, their answers were not enough.
Major comments
1. How did you recognize location of the EGJ? X-ray could not help to recognize the location
of the EGJ. HRM was performed in all patients? Data regarding HRM (diagnoses of esophageal
motility) and impedance-pH monitoring (number of acid and non-acid reflux events and
relationship between symptom and reflux event) should be shown in Table 1. Although there
were several limitations in the study, these data can be shown according to your explanation.
This is very important to understand indications of ESD-G.
Please review this paper.
user
Title: Outcomes of endoscopic submucosal dissection for gastroesophageal reflux disease
(ESD-G) for medication-refractory gastroesophageal reflux disease: 35 cases underwent ESD-
G including 15 cases followed more than 5 years.
Version: 5 Date: 21 Oct 2021
Reviewer:  Shiko Kuribayashi
Reviewer's report:
Authors answered my questions; however, their answers were not enough.
Major comments
1. How did you recognize location of the EGJ? X-ray could not help to recognize the location
of the EGJ. HRM was performed in all patients? Data regarding HRM (diagnoses of esophageal
motility) and impedance-pH monitoring (number of acid and non-acid reflux events and
relationship between symptom and reflux event) should be shown in Table 1. Although there
were several limitations in the study, these data can be shown according to your explanation.
This is very important to understand indications of ESD-G.
assistant