Reviewer's report
Title:The association between cecal insertion time and colorectal neoplasm
detection
Version: 1Date:6 April 2013
Reviewer: Tom Moreels
Reviewer's report:
The authors present a study on the effect of insertion time on adenoma detection
rate in +12,000 screening colonoscopies performed by 23 well-trained (female)
endoscopists. They nicely show the inverse relation between colonic insertion
time and the detection of adenomatous polyps.
Minor Essential Revisions:
1. There are several grammatical errors throughout the manuscript.
2. It is unclear whether polyps were detected during insertion or withdrawal of the
colonoscope. It is generally adviced to remove diminutive polyps during insertion
because of the risk of not finding them back during withdrawal. This should be
clarified.
3. Table 2 shows that multiple and advanced adenomas are also more often
found in colonoscopies with shorter insertion time (p=0.019), as is the case for
diminutive polyps. However, this inverse relationship disappears after adjustment
for confounding factors. The authors should discuss which factors might implicate
this finding.
4. The authors hypotesize that longer insertion times may lead to shorter
withdrawal times and thus resulting in decreased adenoma detection rates. The
authors should further elucidate this by studying the relation between insertion
and withdrawal times in their cohort.
5. Not all references are according to the journal's editorial requirements.
Level of interest: An article of importance in its field
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests.
Reviewer's report
Title:The association between cecal insertion time and colorectal neoplasm
detection
Version: 1Date:6 April 2013
Reviewer: Tom Moreels
Reviewer's report:
The authors present a study on the effect of insertion time on adenoma detection
rate in +12,000 screening colonoscopies performed by 23 well-trained (female)
endoscopists. They nicely show the inverse relation between colonic insertion
time and the detection of adenomatous polyps.
Minor Essential Revisions:
1. There are several grammatical errors throughout the manuscript.
2. It is unclear whether polyps were detected during insertion or withdrawal of the
colonoscope. It is generally adviced to remove diminutive polyps during insertion
because of the risk of not finding them back during withdrawal. This should be
clarified.
3. Table 2 shows that multiple and advanced adenomas are also more often
found in colonoscopies with shorter insertion time (p=0.019), as is the case for
diminutive polyps. However, this inverse relationship disappears after adjustment
for confounding factors. The authors should discuss which factors might implicate
this finding.
4. The authors hypotesize that longer insertion times may lead to shorter
withdrawal times and thus resulting in decreased adenoma detection rates. The
authors should further elucidate this by studying the relation between insertion
and withdrawal times in their cohort.
5. Not all references are according to the journal's editorial requirements.
Level of interest: An article of importance in its field
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests.
Please review this paper.
user
Reviewer's report
Title:The association between cecal insertion time and colorectal neoplasm
detection
Version: 1Date:6 April 2013
Reviewer: Tom Moreels
Reviewer's report:
The authors present a study on the effect of insertion time on adenoma detection
rate in +12,000 screening colonoscopies performed by 23 well-trained (female)
endoscopists. They nicely show the inverse relation between colonic insertion
time and the detection of adenomatous polyps.
Minor Essential Revisions:
1. There are several grammatical errors throughout the manuscript.
2. It is unclear whether polyps were detected during insertion or withdrawal of the
colonoscope. It is generally adviced to remove diminutive polyps during insertion
because of the risk of not finding them back during withdrawal. This should be
clarified.
3. Table 2 shows that multiple and advanced adenomas are also more often
found in colonoscopies with shorter insertion time (p=0.019), as is the case for
diminutive polyps. However, this inverse relationship disappears after adjustment
for confounding factors. The authors should discuss which factors might implicate
this finding.
4. The authors hypotesize that longer insertion times may lead to shorter
withdrawal times and thus resulting in decreased adenoma detection rates. The
authors should further elucidate this by studying the relation between insertion
and withdrawal times in their cohort.
5. Not all references are according to the journal's editorial requirements.
Level of interest: An article of importance in its field
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests.
assistant