Title: IMAGING-BASED DIAGNOSIS OF SARCOPENIA FOR TRANSPLANT-FREE
SURVIVAL IN PRIMARY SCLEROSING CHOLANGITIS
Version: 2 Date: 12 Mar 2024
Reviewer's report:
I congratulate the authors for conducting this important study on the effect of sarcopenia on
transplant-free survival in patients with primary sclerosing cholangitis and a very nicely written
manuscript. Although patient number is small, as PSC is rare, I believe the findings are important
to provoke thoughts on conducting a multicenter and larger studies.
I have few comments:
• Please use keywords that are not included in the title.
• I suggest authors to make supplementary figure 2 as a main table as the majority of death
happened in the for the 12 months, and it will complement the main Figure 2.
• Can authors specifically assess the impact of gender, presence of cirrhosis, decompensation
withing the sarcopenia group etc. as a Kaplan-Meier table (for death as end-point and transplant-
free survival)?
Title: IMAGING-BASED DIAGNOSIS OF SARCOPENIA FOR TRANSPLANT-FREE
SURVIVAL IN PRIMARY SCLEROSING CHOLANGITIS
Version: 2 Date: 12 Mar 2024
Reviewer's report:
I congratulate the authors for conducting this important study on the effect of sarcopenia on
transplant-free survival in patients with primary sclerosing cholangitis and a very nicely written
manuscript. Although patient number is small, as PSC is rare, I believe the findings are important
to provoke thoughts on conducting a multicenter and larger studies.
I have few comments:
• Please use keywords that are not included in the title.
• I suggest authors to make supplementary figure 2 as a main table as the majority of death
happened in the for the 12 months, and it will complement the main Figure 2.
• Can authors specifically assess the impact of gender, presence of cirrhosis, decompensation
withing the sarcopenia group etc. as a Kaplan-Meier table (for death as end-point and transplant-
free survival)?
Please review this paper.
user
Title: IMAGING-BASED DIAGNOSIS OF SARCOPENIA FOR TRANSPLANT-FREE
SURVIVAL IN PRIMARY SCLEROSING CHOLANGITIS
Version: 2 Date: 12 Mar 2024
Reviewer's report:
I congratulate the authors for conducting this important study on the effect of sarcopenia on
transplant-free survival in patients with primary sclerosing cholangitis and a very nicely written
manuscript. Although patient number is small, as PSC is rare, I believe the findings are important
to provoke thoughts on conducting a multicenter and larger studies.
I have few comments:
• Please use keywords that are not included in the title.
• I suggest authors to make supplementary figure 2 as a main table as the majority of death
happened in the for the 12 months, and it will complement the main Figure 2.
• Can authors specifically assess the impact of gender, presence of cirrhosis, decompensation
withing the sarcopenia group etc. as a Kaplan-Meier table (for death as end-point and transplant-
free survival)?
assistant