Reviewer's report
Title:Long-term effects of treatment and response in patients with chronic
hepatitis C on quality of life
Version: 2Date:22 November 2011
Reviewer: GEORGE ABOUDA
Reviewer's report:
The paper is written in good English, the research question is of clinical
relevance, this has been addressed carefully and clearly within the substance of
the literature.
Few comments
1- There are many abbreviations within the text; the authors may do with
reducing it when possible.
2- Many variables are mentioned and these are not shown in comparative table
before and after treatment.
3- There are few questions raised in the results but the authors are not
discussing it , such as why the cirrhotics are doing better than non cirrhotics,
reason of the high drop put rate while it is mentioned in methodology that
questionnaires were given 6 weeks from start of treatment, how did the authors
overcome the country differences ( cultural and social ) is it by the multivariate
analysis and logistic regression .
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: Yes, but I do not feel adequately qualified to assess the
statistics.
Declaration of competing interests:
I declare that I have no competing interests
Reviewer's report
Title:Long-term effects of treatment and response in patients with chronic
hepatitis C on quality of life
Version: 2Date:22 November 2011
Reviewer: GEORGE ABOUDA
Reviewer's report:
The paper is written in good English, the research question is of clinical
relevance, this has been addressed carefully and clearly within the substance of
the literature.
Few comments
1- There are many abbreviations within the text; the authors may do with
reducing it when possible.
2- Many variables are mentioned and these are not shown in comparative table
before and after treatment.
3- There are few questions raised in the results but the authors are not
discussing it , such as why the cirrhotics are doing better than non cirrhotics,
reason of the high drop put rate while it is mentioned in methodology that
questionnaires were given 6 weeks from start of treatment, how did the authors
overcome the country differences ( cultural and social ) is it by the multivariate
analysis and logistic regression .
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: Yes, but I do not feel adequately qualified to assess the
statistics.
Declaration of competing interests:
I declare that I have no competing interests
Please review this paper.
user
Reviewer's report
Title:Long-term effects of treatment and response in patients with chronic
hepatitis C on quality of life
Version: 2Date:22 November 2011
Reviewer: GEORGE ABOUDA
Reviewer's report:
The paper is written in good English, the research question is of clinical
relevance, this has been addressed carefully and clearly within the substance of
the literature.
Few comments
1- There are many abbreviations within the text; the authors may do with
reducing it when possible.
2- Many variables are mentioned and these are not shown in comparative table
before and after treatment.
3- There are few questions raised in the results but the authors are not
discussing it , such as why the cirrhotics are doing better than non cirrhotics,
reason of the high drop put rate while it is mentioned in methodology that
questionnaires were given 6 weeks from start of treatment, how did the authors
overcome the country differences ( cultural and social ) is it by the multivariate
analysis and logistic regression .
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: Yes, but I do not feel adequately qualified to assess the
statistics.
Declaration of competing interests:
I declare that I have no competing interests
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