Reviewer's report
Title:The Prevalence, Incidence and Natural History of Primary Sclerosing
Cholangitis in an Ethnically Diverse Population
Version: 1Date:10 June 2011
Reviewer: Jens J.W. J Tischendorf
Reviewer's report:
The authors wrote a manuscript about PSC patients from diverse ethnical
backgrounds. This topic is very promising since there is only a small knowledge
of the natural course of the disease dependent on race. However, in 53.8% of all
169 patients in this study, the ethnicity is described as “unknown/other”. Among
the remaining small number of PSC patients with known ethnicity, the important
clinical question of risk assessment or determination of prognostic factors for the
natural course of this disease dependent on race cannot be answered. This
drawback should be addressed in the discussion, as the specialty of diverse
ethnicity in this study is highlighted even in the title by the authors. In summary,
this is a well written manuscript, though it is lacking a significant amount of new
information for the reader.
Level of interest: An article of limited interest
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Reviewer's report
Title:The Prevalence, Incidence and Natural History of Primary Sclerosing
Cholangitis in an Ethnically Diverse Population
Version: 1Date:10 June 2011
Reviewer: Jens J.W. J Tischendorf
Reviewer's report:
The authors wrote a manuscript about PSC patients from diverse ethnical
backgrounds. This topic is very promising since there is only a small knowledge
of the natural course of the disease dependent on race. However, in 53.8% of all
169 patients in this study, the ethnicity is described as “unknown/other”. Among
the remaining small number of PSC patients with known ethnicity, the important
clinical question of risk assessment or determination of prognostic factors for the
natural course of this disease dependent on race cannot be answered. This
drawback should be addressed in the discussion, as the specialty of diverse
ethnicity in this study is highlighted even in the title by the authors. In summary,
this is a well written manuscript, though it is lacking a significant amount of new
information for the reader.
Level of interest: An article of limited interest
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Please review this paper.
user
Reviewer's report
Title:The Prevalence, Incidence and Natural History of Primary Sclerosing
Cholangitis in an Ethnically Diverse Population
Version: 1Date:10 June 2011
Reviewer: Jens J.W. J Tischendorf
Reviewer's report:
The authors wrote a manuscript about PSC patients from diverse ethnical
backgrounds. This topic is very promising since there is only a small knowledge
of the natural course of the disease dependent on race. However, in 53.8% of all
169 patients in this study, the ethnicity is described as “unknown/other”. Among
the remaining small number of PSC patients with known ethnicity, the important
clinical question of risk assessment or determination of prognostic factors for the
natural course of this disease dependent on race cannot be answered. This
drawback should be addressed in the discussion, as the specialty of diverse
ethnicity in this study is highlighted even in the title by the authors. In summary,
this is a well written manuscript, though it is lacking a significant amount of new
information for the reader.
Level of interest: An article of limited interest
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
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