Title:  Sex-related Differences in Profiles and Clinical Outcomes of Inflammatory Bowel
Disease: A Systematic Review and Meta-Analysis
Version: 1 Date: 06 Oct 2024
Reviewer:  Panagiotis Tsibouris
Reviewer's report:
Abstract Results on gender effect in separate analysis of CD and UC could be entered in the
abstract if possible Moreover in all disease related matters related to female gender it would be
better to declare those characteristics are more frequent in females. Methods Because gender
effect is not so obvious in children it would be better to exclude patients aged less than 18  Results
Authors should make a separate presentation of UC and CD especially in disease location and
behavior as the two entities are quite different
Title:  Sex-related Differences in Profiles and Clinical Outcomes of Inflammatory Bowel
Disease: A Systematic Review and Meta-Analysis
Version: 1 Date: 06 Oct 2024
Reviewer:  Panagiotis Tsibouris
Reviewer's report:
Abstract Results on gender effect in separate analysis of CD and UC could be entered in the
abstract if possible Moreover in all disease related matters related to female gender it would be
better to declare those characteristics are more frequent in females. Methods Because gender
effect is not so obvious in children it would be better to exclude patients aged less than 18  Results
Authors should make a separate presentation of UC and CD especially in disease location and
behavior as the two entities are quite different
Please review this paper.
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Title:  Sex-related Differences in Profiles and Clinical Outcomes of Inflammatory Bowel
Disease: A Systematic Review and Meta-Analysis
Version: 1 Date: 06 Oct 2024
Reviewer:  Panagiotis Tsibouris
Reviewer's report:
Abstract Results on gender effect in separate analysis of CD and UC could be entered in the
abstract if possible Moreover in all disease related matters related to female gender it would be
better to declare those characteristics are more frequent in females. Methods Because gender
effect is not so obvious in children it would be better to exclude patients aged less than 18  Results
Authors should make a separate presentation of UC and CD especially in disease location and
behavior as the two entities are quite different
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