Title: Symptom effects and central mechanism of acupuncture in patients with functional
gastrointestinal disorders: A systematic review based on fMRI Studies
Version: 1 Date: 16 Oct 2023
Reviewer's report:
This study presents a systematic review of the effects and mechanisms of acupuncture
in the treatment of Functional Gastrointestinal Disorders (FGIDs). Notably, the skin and
central nervous system share a common embryological origin, the ectoderm, which gives
rise to cutaneous visceral reflexes that support the aforementioned investigations. This
observation helps explain, in a natural and comprehensive manner, the significant influence
of acupuncture and moxibustion treatments on various pathological processes, leading to
homeostatic regulation.
Some items may be discussed, including the spontaneous remission of symptoms and potential
placebo effects of acupuncture that should not be excluded. Moreover, the implications of
chronic pain on synaptic plasticity and changes in the CNS and various neural areas that
modulate pain should be considered.
Although the results suggest a benefit of acupuncture, the authors must clarify that there
are insufficient data to recommend the method as a first-line treatment. Moreover, there are
insufficient data to determine the long-term results.
A final open question that requires clarification is whether these procedures are effective only
for symptom relief or their underlying causes. The conclusion should be extended and novel
findings on acupuncture and the regulation of gastrointestinal function should be discussed.
Thank you.
Title: Symptom effects and central mechanism of acupuncture in patients with functional
gastrointestinal disorders: A systematic review based on fMRI Studies
Version: 1 Date: 16 Oct 2023
Reviewer's report:
This study presents a systematic review of the effects and mechanisms of acupuncture
in the treatment of Functional Gastrointestinal Disorders (FGIDs). Notably, the skin and
central nervous system share a common embryological origin, the ectoderm, which gives
rise to cutaneous visceral reflexes that support the aforementioned investigations. This
observation helps explain, in a natural and comprehensive manner, the significant influence
of acupuncture and moxibustion treatments on various pathological processes, leading to
homeostatic regulation.
Some items may be discussed, including the spontaneous remission of symptoms and potential
placebo effects of acupuncture that should not be excluded. Moreover, the implications of
chronic pain on synaptic plasticity and changes in the CNS and various neural areas that
modulate pain should be considered.
Although the results suggest a benefit of acupuncture, the authors must clarify that there
are insufficient data to recommend the method as a first-line treatment. Moreover, there are
insufficient data to determine the long-term results.
A final open question that requires clarification is whether these procedures are effective only
for symptom relief or their underlying causes. The conclusion should be extended and novel
findings on acupuncture and the regulation of gastrointestinal function should be discussed.
Thank you.
Please review this paper.
user
Title: Symptom effects and central mechanism of acupuncture in patients with functional
gastrointestinal disorders: A systematic review based on fMRI Studies
Version: 1 Date: 16 Oct 2023
Reviewer's report:
This study presents a systematic review of the effects and mechanisms of acupuncture
in the treatment of Functional Gastrointestinal Disorders (FGIDs). Notably, the skin and
central nervous system share a common embryological origin, the ectoderm, which gives
rise to cutaneous visceral reflexes that support the aforementioned investigations. This
observation helps explain, in a natural and comprehensive manner, the significant influence
of acupuncture and moxibustion treatments on various pathological processes, leading to
homeostatic regulation.
Some items may be discussed, including the spontaneous remission of symptoms and potential
placebo effects of acupuncture that should not be excluded. Moreover, the implications of
chronic pain on synaptic plasticity and changes in the CNS and various neural areas that
modulate pain should be considered.
Although the results suggest a benefit of acupuncture, the authors must clarify that there
are insufficient data to recommend the method as a first-line treatment. Moreover, there are
insufficient data to determine the long-term results.
A final open question that requires clarification is whether these procedures are effective only
for symptom relief or their underlying causes. The conclusion should be extended and novel
findings on acupuncture and the regulation of gastrointestinal function should be discussed.
Thank you.
assistant