Title: The clinical value of serum sirtuin-1 concentration in the diagnosis of metabolic
dysfunction-associated steatotic liver disease
Version: 0 Date: 11 Nov 2024
Reviewer's report:
The clinical value of serum sirtuin-1 concentration in the diagnosis of metabolic dysfunction-
associated steatotic liver disease: a pilot study This study is not considered as  a pilot study, it
is an observetional study
For the diagnosis of  MASLD : serologic tests that rule out hepatitis B and C ( hepatitis B surface
antigen and hepatitis C virus antibody should be negative)
Recent studies propose increasing the activity of Sirtuin enzymes by decreasing calorie intake
[10]. this reference at 2015 whish not considered as recent studies
Title: The clinical value of serum sirtuin-1 concentration in the diagnosis of metabolic
dysfunction-associated steatotic liver disease
Version: 0 Date: 11 Nov 2024
Reviewer's report:
The clinical value of serum sirtuin-1 concentration in the diagnosis of metabolic dysfunction-
associated steatotic liver disease: a pilot study This study is not considered as  a pilot study, it
is an observetional study
For the diagnosis of  MASLD : serologic tests that rule out hepatitis B and C ( hepatitis B surface
antigen and hepatitis C virus antibody should be negative)
Recent studies propose increasing the activity of Sirtuin enzymes by decreasing calorie intake
[10]. this reference at 2015 whish not considered as recent studies
Please review this paper.
user
Title: The clinical value of serum sirtuin-1 concentration in the diagnosis of metabolic
dysfunction-associated steatotic liver disease
Version: 0 Date: 11 Nov 2024
Reviewer's report:
The clinical value of serum sirtuin-1 concentration in the diagnosis of metabolic dysfunction-
associated steatotic liver disease: a pilot study This study is not considered as  a pilot study, it
is an observetional study
For the diagnosis of  MASLD : serologic tests that rule out hepatitis B and C ( hepatitis B surface
antigen and hepatitis C virus antibody should be negative)
Recent studies propose increasing the activity of Sirtuin enzymes by decreasing calorie intake
[10]. this reference at 2015 whish not considered as recent studies
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