Title: The efficacy of non-anesthesiologist-administered propofol sedation with
a target- controlled infusion system during double-balloon endoscopic retrograde
cholangiopancreatography
Version: 1 Date: 10 Jul 2023
Reviewer's report:
1. This is an article with clinical practicability to solve all therapeutic endoscopy relating pain
relief and anesthesia. Especially, we performed the ERCP in patients of altered anatomy treating
difficult biliary and pancreatic tract diseases.
2. Does the author compares the DB-ERCP examination between “diazepam sedation” and
“propofol sedation” in this article, is there any difference in the procedure-related success rate,
length of time and pancreatitis?
3. Based on your ERCP experience and knowledge, is there a difference in clinical operation
difficulty and success rate between the use of SB-ERCP (single balloon) and DB-ERCP (double
balloon)?
what are the advantages and disadvantages of the two?  such as: easy to do, saving time, complex
altered anatomy….
4. Could the author not only describe the anesthesia medication and process of diazepam sedation
and propofol sedation in wording, but also add the Flow Chart as a figure, which will make it
easier to understand and deepen the reader's impression
Title: The efficacy of non-anesthesiologist-administered propofol sedation with
a target- controlled infusion system during double-balloon endoscopic retrograde
cholangiopancreatography
Version: 1 Date: 10 Jul 2023
Reviewer's report:
1. This is an article with clinical practicability to solve all therapeutic endoscopy relating pain
relief and anesthesia. Especially, we performed the ERCP in patients of altered anatomy treating
difficult biliary and pancreatic tract diseases.
2. Does the author compares the DB-ERCP examination between “diazepam sedation” and
“propofol sedation” in this article, is there any difference in the procedure-related success rate,
length of time and pancreatitis?
3. Based on your ERCP experience and knowledge, is there a difference in clinical operation
difficulty and success rate between the use of SB-ERCP (single balloon) and DB-ERCP (double
balloon)?
what are the advantages and disadvantages of the two?  such as: easy to do, saving time, complex
altered anatomy….
4. Could the author not only describe the anesthesia medication and process of diazepam sedation
and propofol sedation in wording, but also add the Flow Chart as a figure, which will make it
easier to understand and deepen the reader's impression
Please review this paper.
user
Title: The efficacy of non-anesthesiologist-administered propofol sedation with
a target- controlled infusion system during double-balloon endoscopic retrograde
cholangiopancreatography
Version: 1 Date: 10 Jul 2023
Reviewer's report:
1. This is an article with clinical practicability to solve all therapeutic endoscopy relating pain
relief and anesthesia. Especially, we performed the ERCP in patients of altered anatomy treating
difficult biliary and pancreatic tract diseases.
2. Does the author compares the DB-ERCP examination between “diazepam sedation” and
“propofol sedation” in this article, is there any difference in the procedure-related success rate,
length of time and pancreatitis?
3. Based on your ERCP experience and knowledge, is there a difference in clinical operation
difficulty and success rate between the use of SB-ERCP (single balloon) and DB-ERCP (double
balloon)?
what are the advantages and disadvantages of the two?  such as: easy to do, saving time, complex
altered anatomy….
4. Could the author not only describe the anesthesia medication and process of diazepam sedation
and propofol sedation in wording, but also add the Flow Chart as a figure, which will make it
easier to understand and deepen the reader's impression
assistant