Reviewer's report
Title:Over-expression of COX-2 mRNA in colorectal cancer
Version:2Date:6 November 2013
Reviewer: Wenjuan He
Reviewer's report:
The authors have adequately addressed most of my concerns.
- Major Compulsory Revisions
N/A
- Minor Essential Revisions
N/A
- Discretionary Revisions
The authors agree that COX-1 mRNA level will be a good control in their study
(#3). Given that cDNAs from patients have already been generated, it is an easy
experiment to do. COX-1 level will be an important control to show in comparison
to the disease relevant COX-2 level.
Level of interest: An article of limited interest
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
I declare that I have no competing interests.
Reviewer's report
Title:Over-expression of COX-2 mRNA in colorectal cancer
Version:2Date:6 November 2013
Reviewer: Wenjuan He
Reviewer's report:
The authors have adequately addressed most of my concerns.
- Major Compulsory Revisions
N/A
- Minor Essential Revisions
N/A
- Discretionary Revisions
The authors agree that COX-1 mRNA level will be a good control in their study
(#3). Given that cDNAs from patients have already been generated, it is an easy
experiment to do. COX-1 level will be an important control to show in comparison
to the disease relevant COX-2 level.
Level of interest: An article of limited interest
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
I declare that I have no competing interests.
Please review this paper.
user
Reviewer's report
Title:Over-expression of COX-2 mRNA in colorectal cancer
Version:2Date:6 November 2013
Reviewer: Wenjuan He
Reviewer's report:
The authors have adequately addressed most of my concerns.
- Major Compulsory Revisions
N/A
- Minor Essential Revisions
N/A
- Discretionary Revisions
The authors agree that COX-1 mRNA level will be a good control in their study
(#3). Given that cDNAs from patients have already been generated, it is an easy
experiment to do. COX-1 level will be an important control to show in comparison
to the disease relevant COX-2 level.
Level of interest: An article of limited interest
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
I declare that I have no competing interests.
assistant