Title: Analysis of factors related to recanalization of portal vein thrombosis in liver cirrhosis:
a retrospective cohort study
Version: 1 Date: 08 Feb 2024
Reviewer's report:
The study adds up to the literature  supporting anticoagulation therapy for portal vein thrombosis.
The limitations of the study  being retrospective have been put forth.  The following queries
can be addressed
1. whether endoscopy and management of varices have been done before starting on
anticoagulation.  Whether any bleeding risk  was assessed by HAS BLED before anticoagulation.
2. malignant PVT was excluded but is part of the table. (history of previous malignancy- to be
clarified)
3. infectious shock can be replaced by the term septic shock
4. Typing errors - in text and tables to be corrected.  "smoking " and "Rivaroxaban" in tables
5. The meaning of sentences not clear or incomplete.
Abstract: We also further investigated the benefits and risks of anticoagulation therapy in
patients with cirrhotic PVT ."are further investigated" can be  removed.
To further investigate the benefits and risks of anticoagulant therapy in cirrhotic PVT patients.
(Rephrase)
Clinicians often choose not to "anticoagulants" or to reduce the dose of anticoagulants because
they are concerned about the occurrence of bleeding. (Rephrase- anticoagulate)
Title: Analysis of factors related to recanalization of portal vein thrombosis in liver cirrhosis:
a retrospective cohort study
Version: 1 Date: 08 Feb 2024
Reviewer's report:
The study adds up to the literature  supporting anticoagulation therapy for portal vein thrombosis.
The limitations of the study  being retrospective have been put forth.  The following queries
can be addressed
1. whether endoscopy and management of varices have been done before starting on
anticoagulation.  Whether any bleeding risk  was assessed by HAS BLED before anticoagulation.
2. malignant PVT was excluded but is part of the table. (history of previous malignancy- to be
clarified)
3. infectious shock can be replaced by the term septic shock
4. Typing errors - in text and tables to be corrected.  "smoking " and "Rivaroxaban" in tables
5. The meaning of sentences not clear or incomplete.
Abstract: We also further investigated the benefits and risks of anticoagulation therapy in
patients with cirrhotic PVT ."are further investigated" can be  removed.
To further investigate the benefits and risks of anticoagulant therapy in cirrhotic PVT patients.
(Rephrase)
Clinicians often choose not to "anticoagulants" or to reduce the dose of anticoagulants because
they are concerned about the occurrence of bleeding. (Rephrase- anticoagulate)
Please review this paper.
user
Title: Analysis of factors related to recanalization of portal vein thrombosis in liver cirrhosis:
a retrospective cohort study
Version: 1 Date: 08 Feb 2024
Reviewer's report:
The study adds up to the literature  supporting anticoagulation therapy for portal vein thrombosis.
The limitations of the study  being retrospective have been put forth.  The following queries
can be addressed
1. whether endoscopy and management of varices have been done before starting on
anticoagulation.  Whether any bleeding risk  was assessed by HAS BLED before anticoagulation.
2. malignant PVT was excluded but is part of the table. (history of previous malignancy- to be
clarified)
3. infectious shock can be replaced by the term septic shock
4. Typing errors - in text and tables to be corrected.  "smoking " and "Rivaroxaban" in tables
5. The meaning of sentences not clear or incomplete.
Abstract: We also further investigated the benefits and risks of anticoagulation therapy in
patients with cirrhotic PVT ."are further investigated" can be  removed.
To further investigate the benefits and risks of anticoagulant therapy in cirrhotic PVT patients.
(Rephrase)
Clinicians often choose not to "anticoagulants" or to reduce the dose of anticoagulants because
they are concerned about the occurrence of bleeding. (Rephrase- anticoagulate)
assistant