Title: Burden of Gastrointestinal Cancers in Asia, 1990–2019
Version: 0 Date: 24 Feb 2025
Reviewer's report:
1. In the case definition, in addition to the C code, a D code was included. The D code
corresponds to benign neoplasm, carcinoma in situ, etc., but it is uncertain whether benign or
malignant. Please comment on this issue.
2. There are limitations associated with estimating the disease burden in certain countries, as
data quality and availability can vary significantly across different regions and countries.  In
some regions, cancer registries may not be present, or they may have limited coverage and
data quality, making it challenging to provide accurate estimates for specific diseases. Please
comment on this issue.
3. A description and explanation of the risk factors from the database (GBD) will help readers
understand.
Title: Burden of Gastrointestinal Cancers in Asia, 1990–2019
Version: 0 Date: 24 Feb 2025
Reviewer's report:
1. In the case definition, in addition to the C code, a D code was included. The D code
corresponds to benign neoplasm, carcinoma in situ, etc., but it is uncertain whether benign or
malignant. Please comment on this issue.
2. There are limitations associated with estimating the disease burden in certain countries, as
data quality and availability can vary significantly across different regions and countries.  In
some regions, cancer registries may not be present, or they may have limited coverage and
data quality, making it challenging to provide accurate estimates for specific diseases. Please
comment on this issue.
3. A description and explanation of the risk factors from the database (GBD) will help readers
understand.
Please review this paper.
user
Title: Burden of Gastrointestinal Cancers in Asia, 1990–2019
Version: 0 Date: 24 Feb 2025
Reviewer's report:
1. In the case definition, in addition to the C code, a D code was included. The D code
corresponds to benign neoplasm, carcinoma in situ, etc., but it is uncertain whether benign or
malignant. Please comment on this issue.
2. There are limitations associated with estimating the disease burden in certain countries, as
data quality and availability can vary significantly across different regions and countries.  In
some regions, cancer registries may not be present, or they may have limited coverage and
data quality, making it challenging to provide accurate estimates for specific diseases. Please
comment on this issue.
3. A description and explanation of the risk factors from the database (GBD) will help readers
understand.
assistant