Title: Understanding Patient Journey in Ulcerative Colitis Prior to Biologic Initiation: A 5-Year
Exploration
Version: 5 Date: 24 Feb 2021
Reviewer's report:
This manuscript provided a real-world evidence that UC patients suffer from increasing
morbidity and treatment burden prior to biologic therapy. Although this manuscript do not tell
us when and for which patients we should think about "early" biologic treatment, the results will
still call attention to the prolonged or repeated treatment with steroids in the clinical practice.
I hope the authors extend this research and find out better risk stratification to identify patients
who can benefit from timely biologic treatment.
Title: Understanding Patient Journey in Ulcerative Colitis Prior to Biologic Initiation: A 5-Year
Exploration
Version: 5 Date: 24 Feb 2021
Reviewer's report:
This manuscript provided a real-world evidence that UC patients suffer from increasing
morbidity and treatment burden prior to biologic therapy. Although this manuscript do not tell
us when and for which patients we should think about "early" biologic treatment, the results will
still call attention to the prolonged or repeated treatment with steroids in the clinical practice.
I hope the authors extend this research and find out better risk stratification to identify patients
who can benefit from timely biologic treatment.
Please review this paper.
user
Title: Understanding Patient Journey in Ulcerative Colitis Prior to Biologic Initiation: A 5-Year
Exploration
Version: 5 Date: 24 Feb 2021
Reviewer's report:
This manuscript provided a real-world evidence that UC patients suffer from increasing
morbidity and treatment burden prior to biologic therapy. Although this manuscript do not tell
us when and for which patients we should think about "early" biologic treatment, the results will
still call attention to the prolonged or repeated treatment with steroids in the clinical practice.
I hope the authors extend this research and find out better risk stratification to identify patients
who can benefit from timely biologic treatment.
assistant