Title: Construction and validation of a nomogram for predicting survival in elderly patients with
severe acute pancreatitis: a retrospective study from a tertiary center
Version: 2 Date: 28 Apr 2024
Reviewer's report:
#1. The aim of this study is to develop a nomogram for predicting the mortality of severe acute
pancreatitis especially in elderly patients.
The authors collected the laboratory indices on admission. I would like to confirm whether all
patients who included in this study had diagnosed as severe acute pancreatitis on admission.
Are there any patients required to transfer to the ICU during their hospital stay?
#2. (Figure 2A) The numbers shown at the left end of the curves in the graph typically
represent the assigned identifiers for each independent variable (explanatory variable). Whether
an explanation is needed for these numbers or not?
#3. This nomogram model is indeed simple compared to SOFA score. However, this model
includes only factors obtained on admission. It is as if the patient’s prognosis is determined
by the initial condition at admission. I think clinicians usually evaluate the patient’s condition
sequentially and modify treatment strategy. I think it might be a limitation of this study. Please
#4. Authors should mention how this nomogram model demonstrate an effect in clinical setting.
#5. Please check for several typographical errors. For example, “academia (line 243)”.
Title: Construction and validation of a nomogram for predicting survival in elderly patients with
severe acute pancreatitis: a retrospective study from a tertiary center
Version: 2 Date: 28 Apr 2024
Reviewer's report:
#1. The aim of this study is to develop a nomogram for predicting the mortality of severe acute
pancreatitis especially in elderly patients.
The authors collected the laboratory indices on admission. I would like to confirm whether all
patients who included in this study had diagnosed as severe acute pancreatitis on admission.
Are there any patients required to transfer to the ICU during their hospital stay?
#2. (Figure 2A) The numbers shown at the left end of the curves in the graph typically
represent the assigned identifiers for each independent variable (explanatory variable). Whether
an explanation is needed for these numbers or not?
#3. This nomogram model is indeed simple compared to SOFA score. However, this model
includes only factors obtained on admission. It is as if the patient’s prognosis is determined
by the initial condition at admission. I think clinicians usually evaluate the patient’s condition
sequentially and modify treatment strategy. I think it might be a limitation of this study. Please
#4. Authors should mention how this nomogram model demonstrate an effect in clinical setting.
#5. Please check for several typographical errors. For example, “academia (line 243)”.
Please review this paper.
user
Title: Construction and validation of a nomogram for predicting survival in elderly patients with
severe acute pancreatitis: a retrospective study from a tertiary center
Version: 2 Date: 28 Apr 2024
Reviewer's report:
#1. The aim of this study is to develop a nomogram for predicting the mortality of severe acute
pancreatitis especially in elderly patients.
The authors collected the laboratory indices on admission. I would like to confirm whether all
patients who included in this study had diagnosed as severe acute pancreatitis on admission.
Are there any patients required to transfer to the ICU during their hospital stay?
#2. (Figure 2A) The numbers shown at the left end of the curves in the graph typically
represent the assigned identifiers for each independent variable (explanatory variable). Whether
an explanation is needed for these numbers or not?
#3. This nomogram model is indeed simple compared to SOFA score. However, this model
includes only factors obtained on admission. It is as if the patient’s prognosis is determined
by the initial condition at admission. I think clinicians usually evaluate the patient’s condition
sequentially and modify treatment strategy. I think it might be a limitation of this study. Please
#4. Authors should mention how this nomogram model demonstrate an effect in clinical setting.
#5. Please check for several typographical errors. For example, “academia (line 243)”.
assistant