Title: Discrete terminal ileal ulcers in patients diagnosed with ulcerative colitis: clinical
significance and natural course
Version: 2 Date: 03 Jun 2021
Reviewer's report:
This retrospective observational study of nonspecific small ulcers of the terminal ileum in
patients with ulcerative colitis is certainly limited by the fact that it is not a comparative study
with a healthy control group. However, small non-specific ulcers in the terminal ileum are not
uncommon in the daily practice of patients with ulcerative colitis, as demonstrated by the authors'
results. For this reason, additional examinations can be carried out by certain doctors. In this
study, in comparison with previous reports, non-specific small ulcers of the terminal ileum were
more often observed in patients with ulcerative colitis than in healthy subjects, and about 80%
of them healed spontaneously. This new finding non-specific small ulcers in the terminal ileum
in patients with ulcerative colitis have an enough significance in everyday practice, although the
pathological significance of such lesions is limited. In conclusion, I consider that this revised
paper, is worthy of publication.
Title: Discrete terminal ileal ulcers in patients diagnosed with ulcerative colitis: clinical
significance and natural course
Version: 2 Date: 03 Jun 2021
Reviewer's report:
This retrospective observational study of nonspecific small ulcers of the terminal ileum in
patients with ulcerative colitis is certainly limited by the fact that it is not a comparative study
with a healthy control group. However, small non-specific ulcers in the terminal ileum are not
uncommon in the daily practice of patients with ulcerative colitis, as demonstrated by the authors'
results. For this reason, additional examinations can be carried out by certain doctors. In this
study, in comparison with previous reports, non-specific small ulcers of the terminal ileum were
more often observed in patients with ulcerative colitis than in healthy subjects, and about 80%
of them healed spontaneously. This new finding non-specific small ulcers in the terminal ileum
in patients with ulcerative colitis have an enough significance in everyday practice, although the
pathological significance of such lesions is limited. In conclusion, I consider that this revised
paper, is worthy of publication.
Please review this paper.
user
Title: Discrete terminal ileal ulcers in patients diagnosed with ulcerative colitis: clinical
significance and natural course
Version: 2 Date: 03 Jun 2021
Reviewer's report:
This retrospective observational study of nonspecific small ulcers of the terminal ileum in
patients with ulcerative colitis is certainly limited by the fact that it is not a comparative study
with a healthy control group. However, small non-specific ulcers in the terminal ileum are not
uncommon in the daily practice of patients with ulcerative colitis, as demonstrated by the authors'
results. For this reason, additional examinations can be carried out by certain doctors. In this
study, in comparison with previous reports, non-specific small ulcers of the terminal ileum were
more often observed in patients with ulcerative colitis than in healthy subjects, and about 80%
of them healed spontaneously. This new finding non-specific small ulcers in the terminal ileum
in patients with ulcerative colitis have an enough significance in everyday practice, although the
pathological significance of such lesions is limited. In conclusion, I consider that this revised
paper, is worthy of publication.
assistant