Title: Consolidative Chemotherapy after Definitive Concurrent Chemoradiotherapy for
Esophageal Squamous Cell Carcinoma Patients: a Population Based Cohort Study
Version: 1 Date: 17 Jun 2022
Reviewer:  Tetsuhiro Owaki
Reviewer's report:
It corroborates the results of a systematic review of previously reported population-based cohort
studies of oesophageal squamous cell carcinoma, which found that CCT was associated with a
significant improvement in OS in patients with LA-ESCC treated with dCCRT.
In my opinion, the paper is well methodological and does not raise any major issues.
However, some of the following questions need to be addressed
I presume, for some reason unique to Taiwan, that.
1. the reason for drawing the line at age 58
2. the meaning of the difference between northern and non-northern Taiwan
3. the reason for classifying BMI at 18.5.
The above should be added to the discussion.
Title: Consolidative Chemotherapy after Definitive Concurrent Chemoradiotherapy for
Esophageal Squamous Cell Carcinoma Patients: a Population Based Cohort Study
Version: 1 Date: 17 Jun 2022
Reviewer:  Tetsuhiro Owaki
Reviewer's report:
It corroborates the results of a systematic review of previously reported population-based cohort
studies of oesophageal squamous cell carcinoma, which found that CCT was associated with a
significant improvement in OS in patients with LA-ESCC treated with dCCRT.
In my opinion, the paper is well methodological and does not raise any major issues.
However, some of the following questions need to be addressed
I presume, for some reason unique to Taiwan, that.
1. the reason for drawing the line at age 58
2. the meaning of the difference between northern and non-northern Taiwan
3. the reason for classifying BMI at 18.5.
The above should be added to the discussion.
Please review this paper.
user
Title: Consolidative Chemotherapy after Definitive Concurrent Chemoradiotherapy for
Esophageal Squamous Cell Carcinoma Patients: a Population Based Cohort Study
Version: 1 Date: 17 Jun 2022
Reviewer:  Tetsuhiro Owaki
Reviewer's report:
It corroborates the results of a systematic review of previously reported population-based cohort
studies of oesophageal squamous cell carcinoma, which found that CCT was associated with a
significant improvement in OS in patients with LA-ESCC treated with dCCRT.
In my opinion, the paper is well methodological and does not raise any major issues.
However, some of the following questions need to be addressed
I presume, for some reason unique to Taiwan, that.
1. the reason for drawing the line at age 58
2. the meaning of the difference between northern and non-northern Taiwan
3. the reason for classifying BMI at 18.5.
The above should be added to the discussion.
assistant