Reviewer's report
Title:Threaded biliary inside stents are a safe and effective therapeutic option in
cases of malignant hilar obstruction.
Version: 2Date:12 October 2012
Reviewer: Joseph Kim
Reviewer's report:
Major Compulsory Revisions
1. TIS is a poor acronym and should be changed.
2. The authors indicate that, "when the patient was intolerant to reintervention,
increasing jaundice and/or emergence of cholangitis was assumed to indicate
stent occlusion." This is an assumption that is wrong under several
circumstances, e.g., intrahepatic disease progression. Please revise.
3. The authors indicate that, "Three patients who initially received MS underwent
TIS placement because of stent obstruction caused by tumor ingrowth." How
long was the overall survival of these 3 patients? What are the recommendations
for type of stents in such patients?
4. The authors contend that the advantage of TIS is that they can be easily
removed and replaced with occlusion. How often were the TIS replaced because
of occlusion?
5. It appears that there may have been a low rate of occlusion and replacement.
If so, then what is the advantage of the thread in this cohort of patients? Was the
theoretical advantage of the thread realized in this group of patients?
6. The authors reported a stent patency of approximately 30 days for PS. Is this
short period of patency consistent with published reports?
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests.
Reviewer's report
Title:Threaded biliary inside stents are a safe and effective therapeutic option in
cases of malignant hilar obstruction.
Version: 2Date:12 October 2012
Reviewer: Joseph Kim
Reviewer's report:
Major Compulsory Revisions
1. TIS is a poor acronym and should be changed.
2. The authors indicate that, "when the patient was intolerant to reintervention,
increasing jaundice and/or emergence of cholangitis was assumed to indicate
stent occlusion." This is an assumption that is wrong under several
circumstances, e.g., intrahepatic disease progression. Please revise.
3. The authors indicate that, "Three patients who initially received MS underwent
TIS placement because of stent obstruction caused by tumor ingrowth." How
long was the overall survival of these 3 patients? What are the recommendations
for type of stents in such patients?
4. The authors contend that the advantage of TIS is that they can be easily
removed and replaced with occlusion. How often were the TIS replaced because
of occlusion?
5. It appears that there may have been a low rate of occlusion and replacement.
If so, then what is the advantage of the thread in this cohort of patients? Was the
theoretical advantage of the thread realized in this group of patients?
6. The authors reported a stent patency of approximately 30 days for PS. Is this
short period of patency consistent with published reports?
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests.
Please review this paper.
user
Reviewer's report
Title:Threaded biliary inside stents are a safe and effective therapeutic option in
cases of malignant hilar obstruction.
Version: 2Date:12 October 2012
Reviewer: Joseph Kim
Reviewer's report:
Major Compulsory Revisions
1. TIS is a poor acronym and should be changed.
2. The authors indicate that, "when the patient was intolerant to reintervention,
increasing jaundice and/or emergence of cholangitis was assumed to indicate
stent occlusion." This is an assumption that is wrong under several
circumstances, e.g., intrahepatic disease progression. Please revise.
3. The authors indicate that, "Three patients who initially received MS underwent
TIS placement because of stent obstruction caused by tumor ingrowth." How
long was the overall survival of these 3 patients? What are the recommendations
for type of stents in such patients?
4. The authors contend that the advantage of TIS is that they can be easily
removed and replaced with occlusion. How often were the TIS replaced because
of occlusion?
5. It appears that there may have been a low rate of occlusion and replacement.
If so, then what is the advantage of the thread in this cohort of patients? Was the
theoretical advantage of the thread realized in this group of patients?
6. The authors reported a stent patency of approximately 30 days for PS. Is this
short period of patency consistent with published reports?
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests.
assistant