Reviewer's report
Title:Nutritional Status of Adolescents with Crohn's Disease: A Prospective
Cross-sectional Study
Version:2Date:1 July 2015
Reviewer: RACHELE CICCOCIOPPO
Reviewer's report:
GENERAL COMMENTS
The topic of the impact of chronic diseases in general, and of inflammatory bowel
disease in particular, on nutritional status in transitional age is an emerging area
of interest for both researchers and clinicians. In this context, the paper by Costa
and coworkers is of great clinical utility. Although the paper is well presented,
organized in a logical and easy sequence, the length and bibliography
appropriate, there are a number of issues that should be improved. Here below,
please, find more detailed comments.
Minor Essential Revisions
Introduction. A re-organization of the paragraphs in this section is requested to
avoid the fragmentation of the topics.
Methods/results. Although the authors claim that the clinical index of activity was
assessed, no trace of their values (median ± SD in both Crohn’s disease groups)
are given throughout the text and/or in Table 2. Moreover, a correlation between
this score and the level of nutrients should be calculated. In this regard, the worst
iron level observed in the inactive CD group could be explained with a longer
duration of the disease in comparison with the active group, although the values
are not statistically different probably because of a high SD.
The iconography should be presented in a more professional form.
Lastly, although writing is fairly good throughout the text, there are spots where
language revision is needed, and there are a number of typos in the manuscript
that must be corrected (very often DC is used instead CD – at page 11, first line
p<0.05 should be replaced with p>0.05 – the explanation of all acronyms only
should be given only at the first time).
Level of interest: An article of importance in its field
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
I declare That I have no competing interests.
Reviewer's report
Title:Nutritional Status of Adolescents with Crohn's Disease: A Prospective
Cross-sectional Study
Version:2Date:1 July 2015
Reviewer: RACHELE CICCOCIOPPO
Reviewer's report:
GENERAL COMMENTS
The topic of the impact of chronic diseases in general, and of inflammatory bowel
disease in particular, on nutritional status in transitional age is an emerging area
of interest for both researchers and clinicians. In this context, the paper by Costa
and coworkers is of great clinical utility. Although the paper is well presented,
organized in a logical and easy sequence, the length and bibliography
appropriate, there are a number of issues that should be improved. Here below,
please, find more detailed comments.
Minor Essential Revisions
Introduction. A re-organization of the paragraphs in this section is requested to
avoid the fragmentation of the topics.
Methods/results. Although the authors claim that the clinical index of activity was
assessed, no trace of their values (median ± SD in both Crohn’s disease groups)
are given throughout the text and/or in Table 2. Moreover, a correlation between
this score and the level of nutrients should be calculated. In this regard, the worst
iron level observed in the inactive CD group could be explained with a longer
duration of the disease in comparison with the active group, although the values
are not statistically different probably because of a high SD.
The iconography should be presented in a more professional form.
Lastly, although writing is fairly good throughout the text, there are spots where
language revision is needed, and there are a number of typos in the manuscript
that must be corrected (very often DC is used instead CD – at page 11, first line
p<0.05 should be replaced with p>0.05 – the explanation of all acronyms only
should be given only at the first time).
Level of interest: An article of importance in its field
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
I declare That I have no competing interests.
Please review this paper.
user
Reviewer's report
Title:Nutritional Status of Adolescents with Crohn's Disease: A Prospective
Cross-sectional Study
Version:2Date:1 July 2015
Reviewer: RACHELE CICCOCIOPPO
Reviewer's report:
GENERAL COMMENTS
The topic of the impact of chronic diseases in general, and of inflammatory bowel
disease in particular, on nutritional status in transitional age is an emerging area
of interest for both researchers and clinicians. In this context, the paper by Costa
and coworkers is of great clinical utility. Although the paper is well presented,
organized in a logical and easy sequence, the length and bibliography
appropriate, there are a number of issues that should be improved. Here below,
please, find more detailed comments.
Minor Essential Revisions
Introduction. A re-organization of the paragraphs in this section is requested to
avoid the fragmentation of the topics.
Methods/results. Although the authors claim that the clinical index of activity was
assessed, no trace of their values (median ± SD in both Crohn’s disease groups)
are given throughout the text and/or in Table 2. Moreover, a correlation between
this score and the level of nutrients should be calculated. In this regard, the worst
iron level observed in the inactive CD group could be explained with a longer
duration of the disease in comparison with the active group, although the values
are not statistically different probably because of a high SD.
The iconography should be presented in a more professional form.
Lastly, although writing is fairly good throughout the text, there are spots where
language revision is needed, and there are a number of typos in the manuscript
that must be corrected (very often DC is used instead CD – at page 11, first line
p<0.05 should be replaced with p>0.05 – the explanation of all acronyms only
should be given only at the first time).
Level of interest: An article of importance in its field
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
I declare That I have no competing interests.
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