Title: Thiols as a Marker of Inflammatory Bowel Disease Activity: A Systematic Review
Version: 2 Date: 11 Jan 2023
Reviewer's report:
Introduction : have adequately described the literature involving IBD and need for bio markers.
Objective clearly stated. need to correct grammar at places.
Methodology : have described the database searched, mesh terms used, software used for
automation, eligibility criteria,  data extraction and risk of bias.
The final date when a search was conducted needs to be mentioned. which parameters were
extracted needs to be mentioned.
Reason for exclusion of studies need not be mentioned in the methodology and should be shifted
to results. There appears to be a typing error - "CD" is written as "DC" at places and UC is
written as "RCU".  what is "DII" ?
Results: Methodology and findings of the included studies  described adequately. Different
disease activity indices have been used for patients with UC. combining such studies into one
meta analysis does not appear to be appropriate. the last paragraph of results is about limitation
of the study design. It should be shifted to the discussion.
Discussion : adequate
Title: Thiols as a Marker of Inflammatory Bowel Disease Activity: A Systematic Review
Version: 2 Date: 11 Jan 2023
Reviewer's report:
Introduction : have adequately described the literature involving IBD and need for bio markers.
Objective clearly stated. need to correct grammar at places.
Methodology : have described the database searched, mesh terms used, software used for
automation, eligibility criteria,  data extraction and risk of bias.
The final date when a search was conducted needs to be mentioned. which parameters were
extracted needs to be mentioned.
Reason for exclusion of studies need not be mentioned in the methodology and should be shifted
to results. There appears to be a typing error - "CD" is written as "DC" at places and UC is
written as "RCU".  what is "DII" ?
Results: Methodology and findings of the included studies  described adequately. Different
disease activity indices have been used for patients with UC. combining such studies into one
meta analysis does not appear to be appropriate. the last paragraph of results is about limitation
of the study design. It should be shifted to the discussion.
Discussion : adequate
Please review this paper.
user
Title: Thiols as a Marker of Inflammatory Bowel Disease Activity: A Systematic Review
Version: 2 Date: 11 Jan 2023
Reviewer's report:
Introduction : have adequately described the literature involving IBD and need for bio markers.
Objective clearly stated. need to correct grammar at places.
Methodology : have described the database searched, mesh terms used, software used for
automation, eligibility criteria,  data extraction and risk of bias.
The final date when a search was conducted needs to be mentioned. which parameters were
extracted needs to be mentioned.
Reason for exclusion of studies need not be mentioned in the methodology and should be shifted
to results. There appears to be a typing error - "CD" is written as "DC" at places and UC is
written as "RCU".  what is "DII" ?
Results: Methodology and findings of the included studies  described adequately. Different
disease activity indices have been used for patients with UC. combining such studies into one
meta analysis does not appear to be appropriate. the last paragraph of results is about limitation
of the study design. It should be shifted to the discussion.
Discussion : adequate
assistant