Title: Iceball Growth 3D Simulation Model Based on Finite Element Method for Hepatic
Cryoablation Planning
Version: 3 Date: 19 Mar 2025
Reviewer's report:
You can modify the following sentences:
Lines 381-384: The segmentation for cryoprobe and frozen regions was performed by a senior
radiologist (Dr. S. L.) using ITK-SNAP 3.6 software, and subsequently double-checked and
refined by an expert radiologist (Prof. X. L., with more than 20 years of experience in abdominal
radiology).
Modifications:
The segmentation for cryoprobe and frozen regions was performed using ITK-SNAP 3.6
software and subsequently refined.
Lines 431-433: The cryoprobe type was selected by an expert interventionist (Prof. X. L.) with
CT-guided tumor cryoablation experience for more than 15 years based on lesion size and
adjacent critical structures.
Modifications:
Lines 431-433: The cryoprobe type was selected based on lesion size and adjacent critical
structures.
The rest are fine.
This is to avoid bias toward mentioning the experience. Being an experienced professor in the
field does not mean the professor should be correct. Anyhow author contribution section informs
about their contributions.
Title: Iceball Growth 3D Simulation Model Based on Finite Element Method for Hepatic
Cryoablation Planning
Version: 3 Date: 19 Mar 2025
Reviewer's report:
You can modify the following sentences:
Lines 381-384: The segmentation for cryoprobe and frozen regions was performed by a senior
radiologist (Dr. S. L.) using ITK-SNAP 3.6 software, and subsequently double-checked and
refined by an expert radiologist (Prof. X. L., with more than 20 years of experience in abdominal
radiology).
Modifications:
The segmentation for cryoprobe and frozen regions was performed using ITK-SNAP 3.6
software and subsequently refined.
Lines 431-433: The cryoprobe type was selected by an expert interventionist (Prof. X. L.) with
CT-guided tumor cryoablation experience for more than 15 years based on lesion size and
adjacent critical structures.
Modifications:
Lines 431-433: The cryoprobe type was selected based on lesion size and adjacent critical
structures.
The rest are fine.
This is to avoid bias toward mentioning the experience. Being an experienced professor in the
field does not mean the professor should be correct. Anyhow author contribution section informs
about their contributions.
Please review this paper.
user
Title: Iceball Growth 3D Simulation Model Based on Finite Element Method for Hepatic
Cryoablation Planning
Version: 3 Date: 19 Mar 2025
Reviewer's report:
You can modify the following sentences:
Lines 381-384: The segmentation for cryoprobe and frozen regions was performed by a senior
radiologist (Dr. S. L.) using ITK-SNAP 3.6 software, and subsequently double-checked and
refined by an expert radiologist (Prof. X. L., with more than 20 years of experience in abdominal
radiology).
Modifications:
The segmentation for cryoprobe and frozen regions was performed using ITK-SNAP 3.6
software and subsequently refined.
Lines 431-433: The cryoprobe type was selected by an expert interventionist (Prof. X. L.) with
CT-guided tumor cryoablation experience for more than 15 years based on lesion size and
adjacent critical structures.
Modifications:
Lines 431-433: The cryoprobe type was selected based on lesion size and adjacent critical
structures.
The rest are fine.
This is to avoid bias toward mentioning the experience. Being an experienced professor in the
field does not mean the professor should be correct. Anyhow author contribution section informs
about their contributions.
assistant