Title: The emerging epidemic of inflammatory bowel disease in Asia and Iran by 2035: A
modeling study
Version: 2 Date: 22 Feb 2021
Reviewer's report:
Thank you for this work and submission. It was an interesting paper. I appreciate that the authors
are trying to highlight the trends and emerging increase in the prevalence of inflammatory
bowel disease. This is important, yet an extremely complex area of epidemiological research.
I appreciate the goal of the paper. However, I feel that the modeling to generate the predicted
prevalence was too simplified based on current rate of increase. Additionally, I think it is difficult
to model the overall modernization rates, which the authors attribute the increasing incidence
too. Perhaps this complexity can be expanded, detailed and improved. I think the conclusions
drawn from the research are summarized in our need to address the overall worldwide increase
in incidence of IBD is appropriate. Ultimately, I am not sure how novel this concept is to the
readership. Additionally, the methods by which the authors propose to address the increase are
vague. It may be helpful to have more concrete and actionable items on how to reduce the
incidence? Or, if unable to propose a reduction plan, it would be best to move this scope from
the conclusions of the paper. I do appreciate the goal of this paper. However, I think it may
need a bit more depth to inspire the readership - perhaps the authors could consider cost or
financial implications, not only prevalence? or modify their overarching conclusions to include
more concrete and actionable items, like "we would need XX more gastroenterologists, etc".
Title: The emerging epidemic of inflammatory bowel disease in Asia and Iran by 2035: A
modeling study
Version: 2 Date: 22 Feb 2021
Reviewer's report:
Thank you for this work and submission. It was an interesting paper. I appreciate that the authors
are trying to highlight the trends and emerging increase in the prevalence of inflammatory
bowel disease. This is important, yet an extremely complex area of epidemiological research.
I appreciate the goal of the paper. However, I feel that the modeling to generate the predicted
prevalence was too simplified based on current rate of increase. Additionally, I think it is difficult
to model the overall modernization rates, which the authors attribute the increasing incidence
too. Perhaps this complexity can be expanded, detailed and improved. I think the conclusions
drawn from the research are summarized in our need to address the overall worldwide increase
in incidence of IBD is appropriate. Ultimately, I am not sure how novel this concept is to the
readership. Additionally, the methods by which the authors propose to address the increase are
vague. It may be helpful to have more concrete and actionable items on how to reduce the
incidence? Or, if unable to propose a reduction plan, it would be best to move this scope from
the conclusions of the paper. I do appreciate the goal of this paper. However, I think it may
need a bit more depth to inspire the readership - perhaps the authors could consider cost or
financial implications, not only prevalence? or modify their overarching conclusions to include
more concrete and actionable items, like "we would need XX more gastroenterologists, etc".
Please review this paper.
user
Title: The emerging epidemic of inflammatory bowel disease in Asia and Iran by 2035: A
modeling study
Version: 2 Date: 22 Feb 2021
Reviewer's report:
Thank you for this work and submission. It was an interesting paper. I appreciate that the authors
are trying to highlight the trends and emerging increase in the prevalence of inflammatory
bowel disease. This is important, yet an extremely complex area of epidemiological research.
I appreciate the goal of the paper. However, I feel that the modeling to generate the predicted
prevalence was too simplified based on current rate of increase. Additionally, I think it is difficult
to model the overall modernization rates, which the authors attribute the increasing incidence
too. Perhaps this complexity can be expanded, detailed and improved. I think the conclusions
drawn from the research are summarized in our need to address the overall worldwide increase
in incidence of IBD is appropriate. Ultimately, I am not sure how novel this concept is to the
readership. Additionally, the methods by which the authors propose to address the increase are
vague. It may be helpful to have more concrete and actionable items on how to reduce the
incidence? Or, if unable to propose a reduction plan, it would be best to move this scope from
the conclusions of the paper. I do appreciate the goal of this paper. However, I think it may
need a bit more depth to inspire the readership - perhaps the authors could consider cost or
financial implications, not only prevalence? or modify their overarching conclusions to include
more concrete and actionable items, like "we would need XX more gastroenterologists, etc".
assistant