Reviewer's report
Title:Applicability of a short/rapid 13C-urea breath test for Helicobacter pylori: a
retrospective multicenter chart review study
Version: 4Date:9 January 2012
Reviewer: Michael Fried
Reviewer's report:
I have reviewed the manuscript and would recommend to accept it for publication
in BMC Gastroenterology. I do not share the concerns of reviewer 2: The
comparison of this relatively new technology to standard infrared spectrometry
have already been performed and published. Furthermore it is not the goal of the
study to validate BreathID for the detection of HP infection but to explore if this
test would diminish the length of the measurement period. The authors
convincingly demonstrate that BreathID, probably by providing continuous 13C
data can distinctly shorten the measurement time to detect HP in patients. The
authors acknowledge that the high dose of citric acid may have also played a role
to achieve this effect. The findings are important and though this is an
retrospective and not comparative study relevant.
Reviewer's report
Title:Applicability of a short/rapid 13C-urea breath test for Helicobacter pylori: a
retrospective multicenter chart review study
Version: 4Date:9 January 2012
Reviewer: Michael Fried
Reviewer's report:
I have reviewed the manuscript and would recommend to accept it for publication
in BMC Gastroenterology. I do not share the concerns of reviewer 2: The
comparison of this relatively new technology to standard infrared spectrometry
have already been performed and published. Furthermore it is not the goal of the
study to validate BreathID for the detection of HP infection but to explore if this
test would diminish the length of the measurement period. The authors
convincingly demonstrate that BreathID, probably by providing continuous 13C
data can distinctly shorten the measurement time to detect HP in patients. The
authors acknowledge that the high dose of citric acid may have also played a role
to achieve this effect. The findings are important and though this is an
retrospective and not comparative study relevant.
Please review this paper.
user
Reviewer's report
Title:Applicability of a short/rapid 13C-urea breath test for Helicobacter pylori: a
retrospective multicenter chart review study
Version: 4Date:9 January 2012
Reviewer: Michael Fried
Reviewer's report:
I have reviewed the manuscript and would recommend to accept it for publication
in BMC Gastroenterology. I do not share the concerns of reviewer 2: The
comparison of this relatively new technology to standard infrared spectrometry
have already been performed and published. Furthermore it is not the goal of the
study to validate BreathID for the detection of HP infection but to explore if this
test would diminish the length of the measurement period. The authors
convincingly demonstrate that BreathID, probably by providing continuous 13C
data can distinctly shorten the measurement time to detect HP in patients. The
authors acknowledge that the high dose of citric acid may have also played a role
to achieve this effect. The findings are important and though this is an
retrospective and not comparative study relevant.
assistant