Title: Clinical characteristics of Dieulafoy’s Lesion in the Small Bowel Diagnosed and Treated
by Double-Balloon Endoscopy
Version: 1 Date: 27 Mar 2023
Reviewer's report:
Thank you for the opportunity to review this manuscript entitled “Clinical characteristics of
Dieulafoy’s Lesion in the Small Bowel Diagnosed and Treated by Double-Balloon Endoscopy”.
The authors investigated the clinical characteristics of Dieulafoy’s lesion (DL) in the small bowel
by double-balloon endoscopy and the factors to predict DL in obscure gastrointestinal bleeding.
They concluded that DL is suspected in case with two or more episodes of hematochezia.
Although the manuscript are well written, I cannot accept the manuscript as the following
reasons;
Major comments:
1) Definition of hematochezia and re-bleeding should be more clearly described. Additionally,
indication of double-balloon endoscopy is unclear.
2) Authors concluded that in case with two or more episodes of hematochezia, balloon-assisted
endoscopy should be scheduled at the earliest possible time. I think that the result from this
study cannot describe such conclusion because authors did not evaluate the relationship between
time from onset of hematochezia and the procedure in order to obtain definite diagnosis of DL,
particularly to differentiate other conditions such as angiodysplasia.
3) In this study, only lesions which could be diagnosed as DL are included, thus authors
should mention selection bias in the discussion. Difference of clinical characteristics between
angiodysplasia and DL might be more interesting.
Title: Clinical characteristics of Dieulafoy’s Lesion in the Small Bowel Diagnosed and Treated
by Double-Balloon Endoscopy
Version: 1 Date: 27 Mar 2023
Reviewer's report:
Thank you for the opportunity to review this manuscript entitled “Clinical characteristics of
Dieulafoy’s Lesion in the Small Bowel Diagnosed and Treated by Double-Balloon Endoscopy”.
The authors investigated the clinical characteristics of Dieulafoy’s lesion (DL) in the small bowel
by double-balloon endoscopy and the factors to predict DL in obscure gastrointestinal bleeding.
They concluded that DL is suspected in case with two or more episodes of hematochezia.
Although the manuscript are well written, I cannot accept the manuscript as the following
reasons;
Major comments:
1) Definition of hematochezia and re-bleeding should be more clearly described. Additionally,
indication of double-balloon endoscopy is unclear.
2) Authors concluded that in case with two or more episodes of hematochezia, balloon-assisted
endoscopy should be scheduled at the earliest possible time. I think that the result from this
study cannot describe such conclusion because authors did not evaluate the relationship between
time from onset of hematochezia and the procedure in order to obtain definite diagnosis of DL,
particularly to differentiate other conditions such as angiodysplasia.
3) In this study, only lesions which could be diagnosed as DL are included, thus authors
should mention selection bias in the discussion. Difference of clinical characteristics between
angiodysplasia and DL might be more interesting.
Please review this paper.
user
Title: Clinical characteristics of Dieulafoy’s Lesion in the Small Bowel Diagnosed and Treated
by Double-Balloon Endoscopy
Version: 1 Date: 27 Mar 2023
Reviewer's report:
Thank you for the opportunity to review this manuscript entitled “Clinical characteristics of
Dieulafoy’s Lesion in the Small Bowel Diagnosed and Treated by Double-Balloon Endoscopy”.
The authors investigated the clinical characteristics of Dieulafoy’s lesion (DL) in the small bowel
by double-balloon endoscopy and the factors to predict DL in obscure gastrointestinal bleeding.
They concluded that DL is suspected in case with two or more episodes of hematochezia.
Although the manuscript are well written, I cannot accept the manuscript as the following
reasons;
Major comments:
1) Definition of hematochezia and re-bleeding should be more clearly described. Additionally,
indication of double-balloon endoscopy is unclear.
2) Authors concluded that in case with two or more episodes of hematochezia, balloon-assisted
endoscopy should be scheduled at the earliest possible time. I think that the result from this
study cannot describe such conclusion because authors did not evaluate the relationship between
time from onset of hematochezia and the procedure in order to obtain definite diagnosis of DL,
particularly to differentiate other conditions such as angiodysplasia.
3) In this study, only lesions which could be diagnosed as DL are included, thus authors
should mention selection bias in the discussion. Difference of clinical characteristics between
angiodysplasia and DL might be more interesting.
assistant