Reviewer's report
 Treatment of achalasia: the short-term response to botulinum toxin injection is independent of any Title:
kind of pretreatment
Authors:
Martin Storr (martin.storr@lrz.tum.de )
Peter Born (p.born@lrz.tum.de )
Eckhard Frimberger (e.Frimberger@lrz.tum.de )
Norbert Weigert (n.weigert@lrz.tum.de )
Thomas Roesch (troesch@lrz.tum.de )
Alexander Meining (alex.meining@lrz.tum.de )
Meinhard Classen (m.classen@lrz.tum.de )
Hans Allescher (hans.allescher@lrz.tum.de )
 1  25 Jul 2002 Version: Date:
 Dr S Bruley des Varannes Reviewer:
 not specified Level of interest:
 Other (see below) Advice on publication:
This paper reports a single center experience of botulinum toxin injection 
in the the treatment of achalasia. The results of this open study are in 
line with those previously published giving a 6-month rate of remission 
between 60 to 70 % of patients (the two thirds). However the analysis 
according to previous treatments adds some original data showing that 
results are not chnaged by the type of previous treatment. 
In conclusion that is a well written paper confirming now well established 
data. The quality of the paper as well as the analysis of results taking 
into account previous treatments in my opinion justify the publication in BMC Gastroenterology. 
Competing interests:
None declared.
Reviewer's report
 Treatment of achalasia: the short-term response to botulinum toxin injection is independent of any Title:
kind of pretreatment
Authors:
Martin Storr (martin.storr@lrz.tum.de )
Peter Born (p.born@lrz.tum.de )
Eckhard Frimberger (e.Frimberger@lrz.tum.de )
Norbert Weigert (n.weigert@lrz.tum.de )
Thomas Roesch (troesch@lrz.tum.de )
Alexander Meining (alex.meining@lrz.tum.de )
Meinhard Classen (m.classen@lrz.tum.de )
Hans Allescher (hans.allescher@lrz.tum.de )
 1  25 Jul 2002 Version: Date:
 Dr S Bruley des Varannes Reviewer:
 not specified Level of interest:
 Other (see below) Advice on publication:
This paper reports a single center experience of botulinum toxin injection 
in the the treatment of achalasia. The results of this open study are in 
line with those previously published giving a 6-month rate of remission 
between 60 to 70 % of patients (the two thirds). However the analysis 
according to previous treatments adds some original data showing that 
results are not chnaged by the type of previous treatment. 
In conclusion that is a well written paper confirming now well established 
data. The quality of the paper as well as the analysis of results taking 
into account previous treatments in my opinion justify the publication in BMC Gastroenterology. 
Competing interests:
None declared.
Please review this paper.
user
Reviewer's report
 Treatment of achalasia: the short-term response to botulinum toxin injection is independent of any Title:
kind of pretreatment
Authors:
Martin Storr (martin.storr@lrz.tum.de )
Peter Born (p.born@lrz.tum.de )
Eckhard Frimberger (e.Frimberger@lrz.tum.de )
Norbert Weigert (n.weigert@lrz.tum.de )
Thomas Roesch (troesch@lrz.tum.de )
Alexander Meining (alex.meining@lrz.tum.de )
Meinhard Classen (m.classen@lrz.tum.de )
Hans Allescher (hans.allescher@lrz.tum.de )
 1  25 Jul 2002 Version: Date:
 Dr S Bruley des Varannes Reviewer:
 not specified Level of interest:
 Other (see below) Advice on publication:
This paper reports a single center experience of botulinum toxin injection 
in the the treatment of achalasia. The results of this open study are in 
line with those previously published giving a 6-month rate of remission 
between 60 to 70 % of patients (the two thirds). However the analysis 
according to previous treatments adds some original data showing that 
results are not chnaged by the type of previous treatment. 
In conclusion that is a well written paper confirming now well established 
data. The quality of the paper as well as the analysis of results taking 
into account previous treatments in my opinion justify the publication in BMC Gastroenterology. 
Competing interests:
None declared.
assistant