Reviewer's report
Title:The effect of virulence factors on the pathogenicity of Staphylococcus
epidermidis on the intestinal organs of rats and mice: an experimental
investigation
Version:2Date:20 March 2014
Reviewer: Ehinmidu O Olorunmola Joseph
Reviewer's report:
REVIEWER COMMENTS ON: THE EFFECT OF VIRULENCE FACTORS ON
THE PATHOGENICITY OF Staphylococcus epidermidis ON THE INTESTINAL
ORGANS OF RATS AND MICE:
AN EXPERIMENTAL INVESTIGATION:
1. The author’s questions are well defined.
2. Methods used are appropriate, though some methods implied used were not
reported.
i. Surrogate consent of the parents of the children whose samples were implied
used were not properly documented.
ii. The methods for isolation and standardizations of test organisms were not
stated.
iii. The state of nutrient both used to grow the test organisms were unknown.
3. The data reported are scientifically sound.
4. Relevant standards were merely acknowledged but not used.
5. The reports submitted are supported with data.
6. The limitations of the works were not well stated.
7. Reference cited were acknowledged but no 3,11,13,16,17,20 and 22 are not
conforming with standard norm adopted
8. The title and abstract do not accurately conveyed the findings of the work
done. e.g.
a. The virulence factors of the pathogenic test organisms were not lucidly
investigated to warrant the inclusion in the title.
b. The first and last sentence in the abstract has no sufficient data to sustain it
inclusion in the write.
9. The write-up as it is can not be accepted for publication because of a lot of
assumptions that have no data backup. e.g
(i) Staphylococcus epidermidis is frequently isolated species of the Coagulase
negative Staphylococci from human stool. No data was submitted to support this
claim.
(ii) The specific roles of the three virulence factors separately and collectively
were not quantitatively or qualitatively compared with known standards.
10. There are major compulsory revisions before the final decisions on this study
can be made.
Reviewer's report
Title:The effect of virulence factors on the pathogenicity of Staphylococcus
epidermidis on the intestinal organs of rats and mice: an experimental
investigation
Version:2Date:20 March 2014
Reviewer: Ehinmidu O Olorunmola Joseph
Reviewer's report:
REVIEWER COMMENTS ON: THE EFFECT OF VIRULENCE FACTORS ON
THE PATHOGENICITY OF Staphylococcus epidermidis ON THE INTESTINAL
ORGANS OF RATS AND MICE:
AN EXPERIMENTAL INVESTIGATION:
1. The author’s questions are well defined.
2. Methods used are appropriate, though some methods implied used were not
reported.
i. Surrogate consent of the parents of the children whose samples were implied
used were not properly documented.
ii. The methods for isolation and standardizations of test organisms were not
stated.
iii. The state of nutrient both used to grow the test organisms were unknown.
3. The data reported are scientifically sound.
4. Relevant standards were merely acknowledged but not used.
5. The reports submitted are supported with data.
6. The limitations of the works were not well stated.
7. Reference cited were acknowledged but no 3,11,13,16,17,20 and 22 are not
conforming with standard norm adopted
8. The title and abstract do not accurately conveyed the findings of the work
done. e.g.
a. The virulence factors of the pathogenic test organisms were not lucidly
investigated to warrant the inclusion in the title.
b. The first and last sentence in the abstract has no sufficient data to sustain it
inclusion in the write.
9. The write-up as it is can not be accepted for publication because of a lot of
assumptions that have no data backup. e.g
(i) Staphylococcus epidermidis is frequently isolated species of the Coagulase
negative Staphylococci from human stool. No data was submitted to support this
claim.
(ii) The specific roles of the three virulence factors separately and collectively
were not quantitatively or qualitatively compared with known standards.
10. There are major compulsory revisions before the final decisions on this study
can be made.
Please review this paper.
user
Reviewer's report
Title:The effect of virulence factors on the pathogenicity of Staphylococcus
epidermidis on the intestinal organs of rats and mice: an experimental
investigation
Version:2Date:20 March 2014
Reviewer: Ehinmidu O Olorunmola Joseph
Reviewer's report:
REVIEWER COMMENTS ON: THE EFFECT OF VIRULENCE FACTORS ON
THE PATHOGENICITY OF Staphylococcus epidermidis ON THE INTESTINAL
ORGANS OF RATS AND MICE:
AN EXPERIMENTAL INVESTIGATION:
1. The author’s questions are well defined.
2. Methods used are appropriate, though some methods implied used were not
reported.
i. Surrogate consent of the parents of the children whose samples were implied
used were not properly documented.
ii. The methods for isolation and standardizations of test organisms were not
stated.
iii. The state of nutrient both used to grow the test organisms were unknown.
3. The data reported are scientifically sound.
4. Relevant standards were merely acknowledged but not used.
5. The reports submitted are supported with data.
6. The limitations of the works were not well stated.
7. Reference cited were acknowledged but no 3,11,13,16,17,20 and 22 are not
conforming with standard norm adopted
8. The title and abstract do not accurately conveyed the findings of the work
done. e.g.
a. The virulence factors of the pathogenic test organisms were not lucidly
investigated to warrant the inclusion in the title.
b. The first and last sentence in the abstract has no sufficient data to sustain it
inclusion in the write.
9. The write-up as it is can not be accepted for publication because of a lot of
assumptions that have no data backup. e.g
(i) Staphylococcus epidermidis is frequently isolated species of the Coagulase
negative Staphylococci from human stool. No data was submitted to support this
claim.
(ii) The specific roles of the three virulence factors separately and collectively
were not quantitatively or qualitatively compared with known standards.
10. There are major compulsory revisions before the final decisions on this study
can be made.
assistant