Title: The necessarity of treatment for small gastric subepithelial tumors#1cm-2cm# originating
from muscularis propria: An analysis of 972 tumors
Version: 3 Date: 23 Mar 2022
Reviewer's report:
Thank you for your responding to my comment.
Of course, I understand the higher incidence of intermediate or high-risk GIST in 1-2 cm gSET
than 1>. However, should gSETs of 1-2 cm be resected because of the results? The incidence
of intermediate or high-risk GIST in 1-2 cm gSETs was only 2.5% (8/318). Conversely, over
97% of patients did not need to undergo removal. The most important point of this discussion is
whether endoscopic resection of small gSETs is technically and oncologically safe. This study
reveals that 2 of 972 patients experienced perforation and no patients had positive resection
margin. Thus, the procedure is safe. Honestly speaking, I still recognize that such small lesions
does not need resection, but considering the safety of endoscopic resection and the incidence of
high-risk GIST, I finally agree with the authors’ conclusions.
Title: The necessarity of treatment for small gastric subepithelial tumors#1cm-2cm# originating
from muscularis propria: An analysis of 972 tumors
Version: 3 Date: 23 Mar 2022
Reviewer's report:
Thank you for your responding to my comment.
Of course, I understand the higher incidence of intermediate or high-risk GIST in 1-2 cm gSET
than 1>. However, should gSETs of 1-2 cm be resected because of the results? The incidence
of intermediate or high-risk GIST in 1-2 cm gSETs was only 2.5% (8/318). Conversely, over
97% of patients did not need to undergo removal. The most important point of this discussion is
whether endoscopic resection of small gSETs is technically and oncologically safe. This study
reveals that 2 of 972 patients experienced perforation and no patients had positive resection
margin. Thus, the procedure is safe. Honestly speaking, I still recognize that such small lesions
does not need resection, but considering the safety of endoscopic resection and the incidence of
high-risk GIST, I finally agree with the authors’ conclusions.
Please review this paper.
user
Title: The necessarity of treatment for small gastric subepithelial tumors#1cm-2cm# originating
from muscularis propria: An analysis of 972 tumors
Version: 3 Date: 23 Mar 2022
Reviewer's report:
Thank you for your responding to my comment.
Of course, I understand the higher incidence of intermediate or high-risk GIST in 1-2 cm gSET
than 1>. However, should gSETs of 1-2 cm be resected because of the results? The incidence
of intermediate or high-risk GIST in 1-2 cm gSETs was only 2.5% (8/318). Conversely, over
97% of patients did not need to undergo removal. The most important point of this discussion is
whether endoscopic resection of small gSETs is technically and oncologically safe. This study
reveals that 2 of 972 patients experienced perforation and no patients had positive resection
margin. Thus, the procedure is safe. Honestly speaking, I still recognize that such small lesions
does not need resection, but considering the safety of endoscopic resection and the incidence of
high-risk GIST, I finally agree with the authors’ conclusions.
assistant