Reviewer's report
Title:Synchronous carcinoid and gastrointestinal stromal tumour of the stomach:
a case report.
Version: 1Date:9 December 2010
Reviewer: Abbas Agaimy
Reviewer's report:
The author report their experience with a case of gastric carcinoid followed by
GIST and a second carcinoid, this is an interesting case and represents a further
documentation of this phenomenon. It also underscores the importance of getting
biopsy of metachronous lesions.
However some points need be addressed before publication:
Minor Essential Revisions:
1. The number of reported cases is not only 2; Maiorana et al (Arch Pathol Lab
Med 2000) described one other case. This should be quoted. Also, in the review
by agaimy et al (Semin Diagn Pathol, 2006) a total of 13 carcinoid tumors were
associated with GIST, 4 of the carcinoids arose in the stomach. The author
should focus on these relecant papres and not on review-type data on GIST and
their treatment as this is not the focus of their paper).
2. Abstract: it has never been previously described a similar combination of
clinical..
This is clearly overdressing and should be omitted.
3. Introduction:
GISTs show a clear predilection for the gastrointestinal tract.. this makes no
sense as GISTs are by definition gastrointestinal neoplasms.
4. significant parameters..you mean prognosis parameters?
5. Discussion/Conclusion:
it has never been formerly described a similar combination of clinical and
histopathological characteristics. Please correct sentence for symantic and
grammer.
6. Furthermore, our case seems to be the first concerning a male patient.
This is also irrelevant as gender is not a peculiarity in carcinoid or GIST tumors.
7. localized within deeper levels..I think you mean within deeper layers…
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests.
Reviewer's report
Title:Synchronous carcinoid and gastrointestinal stromal tumour of the stomach:
a case report.
Version: 1Date:9 December 2010
Reviewer: Abbas Agaimy
Reviewer's report:
The author report their experience with a case of gastric carcinoid followed by
GIST and a second carcinoid, this is an interesting case and represents a further
documentation of this phenomenon. It also underscores the importance of getting
biopsy of metachronous lesions.
However some points need be addressed before publication:
Minor Essential Revisions:
1. The number of reported cases is not only 2; Maiorana et al (Arch Pathol Lab
Med 2000) described one other case. This should be quoted. Also, in the review
by agaimy et al (Semin Diagn Pathol, 2006) a total of 13 carcinoid tumors were
associated with GIST, 4 of the carcinoids arose in the stomach. The author
should focus on these relecant papres and not on review-type data on GIST and
their treatment as this is not the focus of their paper).
2. Abstract: it has never been previously described a similar combination of
clinical..
This is clearly overdressing and should be omitted.
3. Introduction:
GISTs show a clear predilection for the gastrointestinal tract.. this makes no
sense as GISTs are by definition gastrointestinal neoplasms.
4. significant parameters..you mean prognosis parameters?
5. Discussion/Conclusion:
it has never been formerly described a similar combination of clinical and
histopathological characteristics. Please correct sentence for symantic and
grammer.
6. Furthermore, our case seems to be the first concerning a male patient.
This is also irrelevant as gender is not a peculiarity in carcinoid or GIST tumors.
7. localized within deeper levels..I think you mean within deeper layers…
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests.
Please review this paper.
user
Reviewer's report
Title:Synchronous carcinoid and gastrointestinal stromal tumour of the stomach:
a case report.
Version: 1Date:9 December 2010
Reviewer: Abbas Agaimy
Reviewer's report:
The author report their experience with a case of gastric carcinoid followed by
GIST and a second carcinoid, this is an interesting case and represents a further
documentation of this phenomenon. It also underscores the importance of getting
biopsy of metachronous lesions.
However some points need be addressed before publication:
Minor Essential Revisions:
1. The number of reported cases is not only 2; Maiorana et al (Arch Pathol Lab
Med 2000) described one other case. This should be quoted. Also, in the review
by agaimy et al (Semin Diagn Pathol, 2006) a total of 13 carcinoid tumors were
associated with GIST, 4 of the carcinoids arose in the stomach. The author
should focus on these relecant papres and not on review-type data on GIST and
their treatment as this is not the focus of their paper).
2. Abstract: it has never been previously described a similar combination of
clinical..
This is clearly overdressing and should be omitted.
3. Introduction:
GISTs show a clear predilection for the gastrointestinal tract.. this makes no
sense as GISTs are by definition gastrointestinal neoplasms.
4. significant parameters..you mean prognosis parameters?
5. Discussion/Conclusion:
it has never been formerly described a similar combination of clinical and
histopathological characteristics. Please correct sentence for symantic and
grammer.
6. Furthermore, our case seems to be the first concerning a male patient.
This is also irrelevant as gender is not a peculiarity in carcinoid or GIST tumors.
7. localized within deeper levels..I think you mean within deeper layers…
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests.
assistant