Title: Big Data Analysis of Influenza Vaccination and Liver Cancer Risk in Hypertensive
Patients: Insights from a Nationwide Population-Based Cohort Study
Version: 4 Date: 16 Oct 2024
Reviewer:  Panagiotis Tsibouris
Reviewer's report:
Abstract Uni and multivariated analysis are adequate to unfold relation between influenza
vaccination and HCC Moreover relation of vaccination 10 years post exposure could be
presented Definition of hypertension should be provided Methods Definition of comorbidities
could be provided MAFLD should be included as it could lead in HCC without cirrhosis Time
distance between vaccination and HCC diagnosis should be defined Because at least 10 years
need to develop HCC  such results would be appreciated to be included in the study Instead of
cancer neoplasia would be better definition for exclusion criteria
Title: Big Data Analysis of Influenza Vaccination and Liver Cancer Risk in Hypertensive
Patients: Insights from a Nationwide Population-Based Cohort Study
Version: 4 Date: 16 Oct 2024
Reviewer:  Panagiotis Tsibouris
Reviewer's report:
Abstract Uni and multivariated analysis are adequate to unfold relation between influenza
vaccination and HCC Moreover relation of vaccination 10 years post exposure could be
presented Definition of hypertension should be provided Methods Definition of comorbidities
could be provided MAFLD should be included as it could lead in HCC without cirrhosis Time
distance between vaccination and HCC diagnosis should be defined Because at least 10 years
need to develop HCC  such results would be appreciated to be included in the study Instead of
cancer neoplasia would be better definition for exclusion criteria
Please review this paper.
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Title: Big Data Analysis of Influenza Vaccination and Liver Cancer Risk in Hypertensive
Patients: Insights from a Nationwide Population-Based Cohort Study
Version: 4 Date: 16 Oct 2024
Reviewer:  Panagiotis Tsibouris
Reviewer's report:
Abstract Uni and multivariated analysis are adequate to unfold relation between influenza
vaccination and HCC Moreover relation of vaccination 10 years post exposure could be
presented Definition of hypertension should be provided Methods Definition of comorbidities
could be provided MAFLD should be included as it could lead in HCC without cirrhosis Time
distance between vaccination and HCC diagnosis should be defined Because at least 10 years
need to develop HCC  such results would be appreciated to be included in the study Instead of
cancer neoplasia would be better definition for exclusion criteria
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