Reviewer's report
Title:Validation of the Diffusion-weighted Imaging Method for Activity Evaluation
in Crohn's Disease Patients Underwent Magnetic Resonance Enterography
Version:2Date:27 August 2014
Reviewer: Zhixiang Zuo
Reviewer's report:
*Minor Essential Revisions*
1. The abbreviated words should be completely written when they occur at first
time, for example, MRI, DWI, MR-score-S, CECDAI-S.
2. A summary table is needed for the comparison of sensitivity and specificity
between MRE, DWI and MRE+DWI
3. In Figure 1, the titles for x/y axes should be added
4. Figure 2 only shows the examples of MRE surpassing DWI, however, the
author was intended to prove that MRE+DWI performs better than DWI or MRE
alone.
5. Please explain "Although all MR variables showed
223 the high specificity close to 100%, Area Under the Receiver Operator Curve
(AUROC)
224 indicated that bowel wall enhancement was the optimal predictor of
inflammation
225 (AUROC = 0.87) with the satisfactory sensitiv ity (79.4%) and specific ity
(94.3 %)."
6. Please reconstruct the result "MRE combined with DWI predicts the
endoscopic disease activity"
7. Language should be refined.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
I declare that I have no competing interests
Reviewer's report
Title:Validation of the Diffusion-weighted Imaging Method for Activity Evaluation
in Crohn's Disease Patients Underwent Magnetic Resonance Enterography
Version:2Date:27 August 2014
Reviewer: Zhixiang Zuo
Reviewer's report:
*Minor Essential Revisions*
1. The abbreviated words should be completely written when they occur at first
time, for example, MRI, DWI, MR-score-S, CECDAI-S.
2. A summary table is needed for the comparison of sensitivity and specificity
between MRE, DWI and MRE+DWI
3. In Figure 1, the titles for x/y axes should be added
4. Figure 2 only shows the examples of MRE surpassing DWI, however, the
author was intended to prove that MRE+DWI performs better than DWI or MRE
alone.
5. Please explain "Although all MR variables showed
223 the high specificity close to 100%, Area Under the Receiver Operator Curve
(AUROC)
224 indicated that bowel wall enhancement was the optimal predictor of
inflammation
225 (AUROC = 0.87) with the satisfactory sensitiv ity (79.4%) and specific ity
(94.3 %)."
6. Please reconstruct the result "MRE combined with DWI predicts the
endoscopic disease activity"
7. Language should be refined.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
I declare that I have no competing interests
Please review this paper.
user
Reviewer's report
Title:Validation of the Diffusion-weighted Imaging Method for Activity Evaluation
in Crohn's Disease Patients Underwent Magnetic Resonance Enterography
Version:2Date:27 August 2014
Reviewer: Zhixiang Zuo
Reviewer's report:
*Minor Essential Revisions*
1. The abbreviated words should be completely written when they occur at first
time, for example, MRI, DWI, MR-score-S, CECDAI-S.
2. A summary table is needed for the comparison of sensitivity and specificity
between MRE, DWI and MRE+DWI
3. In Figure 1, the titles for x/y axes should be added
4. Figure 2 only shows the examples of MRE surpassing DWI, however, the
author was intended to prove that MRE+DWI performs better than DWI or MRE
alone.
5. Please explain "Although all MR variables showed
223 the high specificity close to 100%, Area Under the Receiver Operator Curve
(AUROC)
224 indicated that bowel wall enhancement was the optimal predictor of
inflammation
225 (AUROC = 0.87) with the satisfactory sensitiv ity (79.4%) and specific ity
(94.3 %)."
6. Please reconstruct the result "MRE combined with DWI predicts the
endoscopic disease activity"
7. Language should be refined.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
I declare that I have no competing interests
assistant