Title: Title # Endoscopic nasobiliary drainage-based saline-injection ultrasound: an  imaging
technique for remnant stone detection after retrograde cholangiopancreatography
Version: 4 Date: 13 Apr 2022
Reviewer's report:
The purpose of the study that is to determine the accuracy of ENBD-based saline-injection US
for remnant stone detection after ERCP. So it would be interesting to focus the results of ENBD-
based saline-injection US compared to the gold standard that is ERCP with stone extraction.
Additional data should be included in the discussion or be a part of a comparative study.
This is a very interesting study that evaluates the accuracy of enhanced US imaging using ENBD
saline-injection. It is clear the advantages over traditional MRI and CT scan and EUS regarding
cost and simplicity.
There was no information regarding the indication for ENBD in the study.
The objective of the study was to determine the accuracy of ENBD-based saline-injection US
for remnant stone detection after ERCP and in the conclusion of the study there is no mention
of calculation of the accuracy with the collected data.
Line 116 – choledochal cysts
Line 233 and Line 278 and Line 307 – angiography is used as synonym for cholangiography
Title: Title # Endoscopic nasobiliary drainage-based saline-injection ultrasound: an  imaging
technique for remnant stone detection after retrograde cholangiopancreatography
Version: 4 Date: 13 Apr 2022
Reviewer's report:
The purpose of the study that is to determine the accuracy of ENBD-based saline-injection US
for remnant stone detection after ERCP. So it would be interesting to focus the results of ENBD-
based saline-injection US compared to the gold standard that is ERCP with stone extraction.
Additional data should be included in the discussion or be a part of a comparative study.
This is a very interesting study that evaluates the accuracy of enhanced US imaging using ENBD
saline-injection. It is clear the advantages over traditional MRI and CT scan and EUS regarding
cost and simplicity.
There was no information regarding the indication for ENBD in the study.
The objective of the study was to determine the accuracy of ENBD-based saline-injection US
for remnant stone detection after ERCP and in the conclusion of the study there is no mention
of calculation of the accuracy with the collected data.
Line 116 – choledochal cysts
Line 233 and Line 278 and Line 307 – angiography is used as synonym for cholangiography
Please review this paper.
user
Title: Title # Endoscopic nasobiliary drainage-based saline-injection ultrasound: an  imaging
technique for remnant stone detection after retrograde cholangiopancreatography
Version: 4 Date: 13 Apr 2022
Reviewer's report:
The purpose of the study that is to determine the accuracy of ENBD-based saline-injection US
for remnant stone detection after ERCP. So it would be interesting to focus the results of ENBD-
based saline-injection US compared to the gold standard that is ERCP with stone extraction.
Additional data should be included in the discussion or be a part of a comparative study.
This is a very interesting study that evaluates the accuracy of enhanced US imaging using ENBD
saline-injection. It is clear the advantages over traditional MRI and CT scan and EUS regarding
cost and simplicity.
There was no information regarding the indication for ENBD in the study.
The objective of the study was to determine the accuracy of ENBD-based saline-injection US
for remnant stone detection after ERCP and in the conclusion of the study there is no mention
of calculation of the accuracy with the collected data.
Line 116 – choledochal cysts
Line 233 and Line 278 and Line 307 – angiography is used as synonym for cholangiography
assistant