Title: The Reflux Symptom Score has good screening value for Laryngopharyngeal Reflux
Version: 1 Date: 07 Jul 2024
Reviewer's report:
This article compared RSS and salivary pepsin of LPR patients, investigated the consistency
of RSS and its screening value in diagnosing LPR.   The topic made sense in applying RSS in
China LPR patients, as RSI and RFS have their limitations, pH monitoring cannot be widely
used because the fee, uncomfortable, invasiveness etc. So  I  suppose this article to be published.
But I have several questions and opinions:
1. In the inclusion criteria, the patients had long-term LPR symptoms, so how long did they have
them? Is there a criteria in the case history?
2. In the exclusion criteria, were the  patients included, if they had surgery, trauma, acupuncture
recently?
3. The article said all patients had electronic laryngoscope  examination, then what were the
results and how were their RFS?
4. As all patients had RSS, how their RSI, as RSS included all RSI items?
5. As the salivary pepsin series were performed by patients themselves, how the consistency  of
the procedure was kept, as this can directly affect the results?
Title: The Reflux Symptom Score has good screening value for Laryngopharyngeal Reflux
Version: 1 Date: 07 Jul 2024
Reviewer's report:
This article compared RSS and salivary pepsin of LPR patients, investigated the consistency
of RSS and its screening value in diagnosing LPR.   The topic made sense in applying RSS in
China LPR patients, as RSI and RFS have their limitations, pH monitoring cannot be widely
used because the fee, uncomfortable, invasiveness etc. So  I  suppose this article to be published.
But I have several questions and opinions:
1. In the inclusion criteria, the patients had long-term LPR symptoms, so how long did they have
them? Is there a criteria in the case history?
2. In the exclusion criteria, were the  patients included, if they had surgery, trauma, acupuncture
recently?
3. The article said all patients had electronic laryngoscope  examination, then what were the
results and how were their RFS?
4. As all patients had RSS, how their RSI, as RSS included all RSI items?
5. As the salivary pepsin series were performed by patients themselves, how the consistency  of
the procedure was kept, as this can directly affect the results?
Please review this paper.
user
Title: The Reflux Symptom Score has good screening value for Laryngopharyngeal Reflux
Version: 1 Date: 07 Jul 2024
Reviewer's report:
This article compared RSS and salivary pepsin of LPR patients, investigated the consistency
of RSS and its screening value in diagnosing LPR.   The topic made sense in applying RSS in
China LPR patients, as RSI and RFS have their limitations, pH monitoring cannot be widely
used because the fee, uncomfortable, invasiveness etc. So  I  suppose this article to be published.
But I have several questions and opinions:
1. In the inclusion criteria, the patients had long-term LPR symptoms, so how long did they have
them? Is there a criteria in the case history?
2. In the exclusion criteria, were the  patients included, if they had surgery, trauma, acupuncture
recently?
3. The article said all patients had electronic laryngoscope  examination, then what were the
results and how were their RFS?
4. As all patients had RSS, how their RSI, as RSS included all RSI items?
5. As the salivary pepsin series were performed by patients themselves, how the consistency  of
the procedure was kept, as this can directly affect the results?
assistant