Title: The molecular characteristics of gastric cancer patients living in Qinghai-Tibetan Plateau
Version: 4 Date: 16 Apr 2022
Reviewer's report:
This work attempts research the molecular characteristics of gastric cancer patients living in
Qinghai-Tibetan Plateau. They collected about 30 patients from Qinghai Provincial People’s
Hospital, and identified the molecular variations via whole exome sequencing. They found some
special characteristics for those gastric patients living in Qinghai-Tibetan Plateau, including
younger initial diagnosis age, most variations found in chromosome 7, et al. There are some
issues have to be addressed before publication.
1. The authors should link the molecular characteristics with some clinical features, for instance
talk about the differences in molecular variations between different minority nationality and Han
Chinese, the differences in molecular variations among different tumor stages, et al.
2. More clinical features should be discussed here, like tumor stage, survival, et al.
3. The authors should discuss the difference between patients living in Qinghai-Tibetan Plateau
and patients living in low-altitude place.
4. Double check the typos and grammar issues.
Title: The molecular characteristics of gastric cancer patients living in Qinghai-Tibetan Plateau
Version: 4 Date: 16 Apr 2022
Reviewer's report:
This work attempts research the molecular characteristics of gastric cancer patients living in
Qinghai-Tibetan Plateau. They collected about 30 patients from Qinghai Provincial People’s
Hospital, and identified the molecular variations via whole exome sequencing. They found some
special characteristics for those gastric patients living in Qinghai-Tibetan Plateau, including
younger initial diagnosis age, most variations found in chromosome 7, et al. There are some
issues have to be addressed before publication.
1. The authors should link the molecular characteristics with some clinical features, for instance
talk about the differences in molecular variations between different minority nationality and Han
Chinese, the differences in molecular variations among different tumor stages, et al.
2. More clinical features should be discussed here, like tumor stage, survival, et al.
3. The authors should discuss the difference between patients living in Qinghai-Tibetan Plateau
and patients living in low-altitude place.
4. Double check the typos and grammar issues.
Please review this paper.
user
Title: The molecular characteristics of gastric cancer patients living in Qinghai-Tibetan Plateau
Version: 4 Date: 16 Apr 2022
Reviewer's report:
This work attempts research the molecular characteristics of gastric cancer patients living in
Qinghai-Tibetan Plateau. They collected about 30 patients from Qinghai Provincial People’s
Hospital, and identified the molecular variations via whole exome sequencing. They found some
special characteristics for those gastric patients living in Qinghai-Tibetan Plateau, including
younger initial diagnosis age, most variations found in chromosome 7, et al. There are some
issues have to be addressed before publication.
1. The authors should link the molecular characteristics with some clinical features, for instance
talk about the differences in molecular variations between different minority nationality and Han
Chinese, the differences in molecular variations among different tumor stages, et al.
2. More clinical features should be discussed here, like tumor stage, survival, et al.
3. The authors should discuss the difference between patients living in Qinghai-Tibetan Plateau
and patients living in low-altitude place.
4. Double check the typos and grammar issues.
assistant