Reviewer's report 
 A comparison of Child-Pugh, APACHE II and APACHE III scoring systems in predicting Title: 
hospital mortality of patients with liver cirrhosis 
Authors: 
Constantinos Chatzicostas ( matrix01gr@yahoo.gr )
Dr Maria Roussomoustakaki ( mrousso1@hotmail.com )
Georgios Notas ( chief@med.uoc.gr )
Ioannis G Vlachonikolis ( i.vlachonikolis@surrey.ac.uk )
Demetrios Samonakis ( photein@in.gr )
John Romanos ( romanos@med.uoc.gr )
Emmanouel Vardas ( evardas@hotmail.com )
Prof Elias A Kouroumalis ( kouroum@med.uoc.gr )
 3  17 Mar 2003 Version: Date: 
 Markus Wehler Reviewer: 
 A paper whose findings are important to those with closely related research Level of interest: 
interests 
 Accept after discretionary revisions Advice on publication: 
The questions of the reviewers were answered point by point. The proposed goodness of fit statistic 
changed the results of the manuscript completely. The methods are appropriate and well described, 
results adhere to the relevant standards for reporting and data deposition. The discussion points out 
the major problems associated with such research and the conclusions apply to the reported data. 
Discretionary revisions: 
1. The title should indicate that ward patients and not critically ill patients were investigated. 
2. The expression "strata of increasing predicting mortality" (page 2, last para, and page 12) is difficult to understand and should be rephrased. 
Competing interests: 
None declared. 
Reviewer's report 
 A comparison of Child-Pugh, APACHE II and APACHE III scoring systems in predicting Title: 
hospital mortality of patients with liver cirrhosis 
Authors: 
Constantinos Chatzicostas ( matrix01gr@yahoo.gr )
Dr Maria Roussomoustakaki ( mrousso1@hotmail.com )
Georgios Notas ( chief@med.uoc.gr )
Ioannis G Vlachonikolis ( i.vlachonikolis@surrey.ac.uk )
Demetrios Samonakis ( photein@in.gr )
John Romanos ( romanos@med.uoc.gr )
Emmanouel Vardas ( evardas@hotmail.com )
Prof Elias A Kouroumalis ( kouroum@med.uoc.gr )
 3  17 Mar 2003 Version: Date: 
 Markus Wehler Reviewer: 
 A paper whose findings are important to those with closely related research Level of interest: 
interests 
 Accept after discretionary revisions Advice on publication: 
The questions of the reviewers were answered point by point. The proposed goodness of fit statistic 
changed the results of the manuscript completely. The methods are appropriate and well described, 
results adhere to the relevant standards for reporting and data deposition. The discussion points out 
the major problems associated with such research and the conclusions apply to the reported data. 
Discretionary revisions: 
1. The title should indicate that ward patients and not critically ill patients were investigated. 
2. The expression "strata of increasing predicting mortality" (page 2, last para, and page 12) is difficult to understand and should be rephrased. 
Competing interests: 
None declared. 
Please review this paper.
user
Reviewer's report 
 A comparison of Child-Pugh, APACHE II and APACHE III scoring systems in predicting Title: 
hospital mortality of patients with liver cirrhosis 
Authors: 
Constantinos Chatzicostas ( matrix01gr@yahoo.gr )
Dr Maria Roussomoustakaki ( mrousso1@hotmail.com )
Georgios Notas ( chief@med.uoc.gr )
Ioannis G Vlachonikolis ( i.vlachonikolis@surrey.ac.uk )
Demetrios Samonakis ( photein@in.gr )
John Romanos ( romanos@med.uoc.gr )
Emmanouel Vardas ( evardas@hotmail.com )
Prof Elias A Kouroumalis ( kouroum@med.uoc.gr )
 3  17 Mar 2003 Version: Date: 
 Markus Wehler Reviewer: 
 A paper whose findings are important to those with closely related research Level of interest: 
interests 
 Accept after discretionary revisions Advice on publication: 
The questions of the reviewers were answered point by point. The proposed goodness of fit statistic 
changed the results of the manuscript completely. The methods are appropriate and well described, 
results adhere to the relevant standards for reporting and data deposition. The discussion points out 
the major problems associated with such research and the conclusions apply to the reported data. 
Discretionary revisions: 
1. The title should indicate that ward patients and not critically ill patients were investigated. 
2. The expression "strata of increasing predicting mortality" (page 2, last para, and page 12) is difficult to understand and should be rephrased. 
Competing interests: 
None declared. 
assistant