Title: The nomograph predicting the recurrence of Solid Pseudopapillary Neoplasm of the
Pancreas: a study of the SEER database and a Chinese cohort
Version: 1 Date: 18 Jan 2025
Reviewer's report:
In this manuscript, the authors demonstrated the details of SPN recurrence. SPN is very rare
tumor, so this manuscript is meaningful. However, this manuscript need to improve some
content.
1. The surgical procedures (for example, PD, DP, TP, MP, enucleation, and so on), the range of
lymphadenectomy (D0, D1 or D2), and the regimen of chemotherapy should have been shown.
2. Please provide the recurrence rate and the recurrent-free survival time in R0 resection cases.
3. This manuscript showed the chemoradiotherapy can reduce the risk of recurrence. Dose this
mean that performing both chemotherapy and radiotherapy can reduce the risk of recurrence?
Does the chemoradiotherapy perform preoperatively or postoperatively?   The details of
chemoradiotherapy should have been shown.
Title: The nomograph predicting the recurrence of Solid Pseudopapillary Neoplasm of the
Pancreas: a study of the SEER database and a Chinese cohort
Version: 1 Date: 18 Jan 2025
Reviewer's report:
In this manuscript, the authors demonstrated the details of SPN recurrence. SPN is very rare
tumor, so this manuscript is meaningful. However, this manuscript need to improve some
content.
1. The surgical procedures (for example, PD, DP, TP, MP, enucleation, and so on), the range of
lymphadenectomy (D0, D1 or D2), and the regimen of chemotherapy should have been shown.
2. Please provide the recurrence rate and the recurrent-free survival time in R0 resection cases.
3. This manuscript showed the chemoradiotherapy can reduce the risk of recurrence. Dose this
mean that performing both chemotherapy and radiotherapy can reduce the risk of recurrence?
Does the chemoradiotherapy perform preoperatively or postoperatively?   The details of
chemoradiotherapy should have been shown.
Please review this paper.
user
Title: The nomograph predicting the recurrence of Solid Pseudopapillary Neoplasm of the
Pancreas: a study of the SEER database and a Chinese cohort
Version: 1 Date: 18 Jan 2025
Reviewer's report:
In this manuscript, the authors demonstrated the details of SPN recurrence. SPN is very rare
tumor, so this manuscript is meaningful. However, this manuscript need to improve some
content.
1. The surgical procedures (for example, PD, DP, TP, MP, enucleation, and so on), the range of
lymphadenectomy (D0, D1 or D2), and the regimen of chemotherapy should have been shown.
2. Please provide the recurrence rate and the recurrent-free survival time in R0 resection cases.
3. This manuscript showed the chemoradiotherapy can reduce the risk of recurrence. Dose this
mean that performing both chemotherapy and radiotherapy can reduce the risk of recurrence?
Does the chemoradiotherapy perform preoperatively or postoperatively?   The details of
chemoradiotherapy should have been shown.
assistant