Title: Association of circulating tumor cell-white blood cell clusters with survival outcomes in
patients with colorectal cancer after curative intent surgery
Version: 1 Date: 28 Sep 2022
Reviewer's report:
this is a very good topic looking at the association of CtC associated WBC clusters and prognosis
of CRC. i think the concept is very interesting and authors show that CTC - WBC is associated
with poor disease free survival. The clinical significance of this is valid and important.
As far as the study design goes the authors say the study is retrospective and I am not sure how
the authors get the blood tests to analyse the CTC associated WBC retrospectively.. THis will
have significant impact on the outcome of the study
further explanation of this is needed
Title: Association of circulating tumor cell-white blood cell clusters with survival outcomes in
patients with colorectal cancer after curative intent surgery
Version: 1 Date: 28 Sep 2022
Reviewer's report:
this is a very good topic looking at the association of CtC associated WBC clusters and prognosis
of CRC. i think the concept is very interesting and authors show that CTC - WBC is associated
with poor disease free survival. The clinical significance of this is valid and important.
As far as the study design goes the authors say the study is retrospective and I am not sure how
the authors get the blood tests to analyse the CTC associated WBC retrospectively.. THis will
have significant impact on the outcome of the study
further explanation of this is needed
Please review this paper.
user
Title: Association of circulating tumor cell-white blood cell clusters with survival outcomes in
patients with colorectal cancer after curative intent surgery
Version: 1 Date: 28 Sep 2022
Reviewer's report:
this is a very good topic looking at the association of CtC associated WBC clusters and prognosis
of CRC. i think the concept is very interesting and authors show that CTC - WBC is associated
with poor disease free survival. The clinical significance of this is valid and important.
As far as the study design goes the authors say the study is retrospective and I am not sure how
the authors get the blood tests to analyse the CTC associated WBC retrospectively.. THis will
have significant impact on the outcome of the study
further explanation of this is needed
assistant