Title: Influence of a novel classification of the papilla of Vater on the outcome of needle-knife
fistulotomy for biliary cannulation
Version: 1 Date: 15 Feb 2021
Reviewer's report:
This seems to be a prospective observational study that objectively verified the novel
classification system of PV devised by the authors.
Major revision
1. The methods for selective biliary cannulation known so far are very diverse, and the
methods may be different depending on the preference of the endoscopist or each endoscopist’s
familiarity with a specific device. In addition, the selection of the 2nd line method may vary
depending on the situation when attempting the first line procedure. In order to evaluate the
clinical usefulness of the proposed PV morphology new classification system, I wonder why the
authors selected the success or failure of NKF and the occurrence of complications as clinical
indicators among several methods of selective biliary cannulation. So, please elaborate this in
the introduction and discussion sections.
2. The content of the method is too long and verbose. Please describe in abbreviated terms
focusing on the core content.
Minor revision
1. In the conclusion, state that this novel classification system would be a guide to selecting
the most optimal biliary cannulation option for each patient though the subsequent clinical
verification process.
2. Please correct any typos pointed out by a reviewer in the manuscript.
Title: Influence of a novel classification of the papilla of Vater on the outcome of needle-knife
fistulotomy for biliary cannulation
Version: 1 Date: 15 Feb 2021
Reviewer's report:
This seems to be a prospective observational study that objectively verified the novel
classification system of PV devised by the authors.
Major revision
1. The methods for selective biliary cannulation known so far are very diverse, and the
methods may be different depending on the preference of the endoscopist or each endoscopist’s
familiarity with a specific device. In addition, the selection of the 2nd line method may vary
depending on the situation when attempting the first line procedure. In order to evaluate the
clinical usefulness of the proposed PV morphology new classification system, I wonder why the
authors selected the success or failure of NKF and the occurrence of complications as clinical
indicators among several methods of selective biliary cannulation. So, please elaborate this in
the introduction and discussion sections.
2. The content of the method is too long and verbose. Please describe in abbreviated terms
focusing on the core content.
Minor revision
1. In the conclusion, state that this novel classification system would be a guide to selecting
the most optimal biliary cannulation option for each patient though the subsequent clinical
verification process.
2. Please correct any typos pointed out by a reviewer in the manuscript.
Please review this paper.
user
Title: Influence of a novel classification of the papilla of Vater on the outcome of needle-knife
fistulotomy for biliary cannulation
Version: 1 Date: 15 Feb 2021
Reviewer's report:
This seems to be a prospective observational study that objectively verified the novel
classification system of PV devised by the authors.
Major revision
1. The methods for selective biliary cannulation known so far are very diverse, and the
methods may be different depending on the preference of the endoscopist or each endoscopist’s
familiarity with a specific device. In addition, the selection of the 2nd line method may vary
depending on the situation when attempting the first line procedure. In order to evaluate the
clinical usefulness of the proposed PV morphology new classification system, I wonder why the
authors selected the success or failure of NKF and the occurrence of complications as clinical
indicators among several methods of selective biliary cannulation. So, please elaborate this in
the introduction and discussion sections.
2. The content of the method is too long and verbose. Please describe in abbreviated terms
focusing on the core content.
Minor revision
1. In the conclusion, state that this novel classification system would be a guide to selecting
the most optimal biliary cannulation option for each patient though the subsequent clinical
verification process.
2. Please correct any typos pointed out by a reviewer in the manuscript.
assistant