Title: Clinical characteristics and management of liver abscess in The Gambia, a resource
limited countries
Version: 6 Date: 09 Jun 2024
Reviewer's report:
This paper has fundamental drawback in methodology - treatment section. It says  it is a
retrospective study. data collected retrospectively from records.
In the methodology  authors describe a strict  management startegy. To treat with antibiotics if
the abscess size is less then 5 cm and aspirate and give antibiotics if it is over 5 cm. this 5cm is
highly arbitrary and there is no such division in clinical practice. Aspiration /admission  is all
individualized. I do not think such a practice is acceptable and possible even in resource poor
setting.
Similarly in treatment it says large abscess after aspiration was observed for 4 hours and if vitals
were stable they were discharged. These patients having large abscesses usually need aggressive
IV antibiotics and such strict protocol cannot be practiced.
Title: Clinical characteristics and management of liver abscess in The Gambia, a resource
limited countries
Version: 6 Date: 09 Jun 2024
Reviewer's report:
This paper has fundamental drawback in methodology - treatment section. It says  it is a
retrospective study. data collected retrospectively from records.
In the methodology  authors describe a strict  management startegy. To treat with antibiotics if
the abscess size is less then 5 cm and aspirate and give antibiotics if it is over 5 cm. this 5cm is
highly arbitrary and there is no such division in clinical practice. Aspiration /admission  is all
individualized. I do not think such a practice is acceptable and possible even in resource poor
setting.
Similarly in treatment it says large abscess after aspiration was observed for 4 hours and if vitals
were stable they were discharged. These patients having large abscesses usually need aggressive
IV antibiotics and such strict protocol cannot be practiced.
Please review this paper.
user
Title: Clinical characteristics and management of liver abscess in The Gambia, a resource
limited countries
Version: 6 Date: 09 Jun 2024
Reviewer's report:
This paper has fundamental drawback in methodology - treatment section. It says  it is a
retrospective study. data collected retrospectively from records.
In the methodology  authors describe a strict  management startegy. To treat with antibiotics if
the abscess size is less then 5 cm and aspirate and give antibiotics if it is over 5 cm. this 5cm is
highly arbitrary and there is no such division in clinical practice. Aspiration /admission  is all
individualized. I do not think such a practice is acceptable and possible even in resource poor
setting.
Similarly in treatment it says large abscess after aspiration was observed for 4 hours and if vitals
were stable they were discharged. These patients having large abscesses usually need aggressive
IV antibiotics and such strict protocol cannot be practiced.
assistant