Title: Bowel Preparation Using 2-Liter Split-dose Polyethylene Glycol Regimen Plus
Lubiprostone Versus 4-Liter Split-dose Polyethylene Glycol Regimen: A Randomized
Controlled Trial
Version: 2 Date: 10 Jul 2022
Reviewer's report:
Dear all,
I have had the pleasure to read the reseach article by Sirinawasatien et al. The draft is well written
and the trial seem logically constructed. Methods and statistics are well described. The colon
cleansing regime with 2 l PEG spit dose plus prior lubiprostone is new and has not been reported
so far. Results are clearly presented, if somewhat to be expected since lubiprostine showed in
a meta-analysis from 2016 a higher rate of patients with excellent colon cleansing in different
colon cleansing regimes. Nevertheless, this is  new and importand data in this field. I have just
one little annotation for the figures 2 and 3 to please add the subject number (N) of each group
in the caption.
In summary I support the publication of the article.
Title: Bowel Preparation Using 2-Liter Split-dose Polyethylene Glycol Regimen Plus
Lubiprostone Versus 4-Liter Split-dose Polyethylene Glycol Regimen: A Randomized
Controlled Trial
Version: 2 Date: 10 Jul 2022
Reviewer's report:
Dear all,
I have had the pleasure to read the reseach article by Sirinawasatien et al. The draft is well written
and the trial seem logically constructed. Methods and statistics are well described. The colon
cleansing regime with 2 l PEG spit dose plus prior lubiprostone is new and has not been reported
so far. Results are clearly presented, if somewhat to be expected since lubiprostine showed in
a meta-analysis from 2016 a higher rate of patients with excellent colon cleansing in different
colon cleansing regimes. Nevertheless, this is  new and importand data in this field. I have just
one little annotation for the figures 2 and 3 to please add the subject number (N) of each group
in the caption.
In summary I support the publication of the article.
Please review this paper.
user
Title: Bowel Preparation Using 2-Liter Split-dose Polyethylene Glycol Regimen Plus
Lubiprostone Versus 4-Liter Split-dose Polyethylene Glycol Regimen: A Randomized
Controlled Trial
Version: 2 Date: 10 Jul 2022
Reviewer's report:
Dear all,
I have had the pleasure to read the reseach article by Sirinawasatien et al. The draft is well written
and the trial seem logically constructed. Methods and statistics are well described. The colon
cleansing regime with 2 l PEG spit dose plus prior lubiprostone is new and has not been reported
so far. Results are clearly presented, if somewhat to be expected since lubiprostine showed in
a meta-analysis from 2016 a higher rate of patients with excellent colon cleansing in different
colon cleansing regimes. Nevertheless, this is  new and importand data in this field. I have just
one little annotation for the figures 2 and 3 to please add the subject number (N) of each group
in the caption.
In summary I support the publication of the article.
assistant