Reviewer's report
Title:Time Esophageal pH<4 Overestimates the Prevalence of Pathologic
Esophageal Reflux in Subjects with Gastroesophageal Reflux Disease Treated
with Proton Pump Inhibitors
Version: 3Date:17 April 2008
Reviewer: Martin Fein
Reviewer's report:
In response to my review the paper has been considerably improved.
It contains a clear description of the method of gastric integrated acidity
and a detailed discussion on its potential clinical relevance.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests
Reviewer's report
Title:Time Esophageal pH<4 Overestimates the Prevalence of Pathologic
Esophageal Reflux in Subjects with Gastroesophageal Reflux Disease Treated
with Proton Pump Inhibitors
Version: 3Date:17 April 2008
Reviewer: Martin Fein
Reviewer's report:
In response to my review the paper has been considerably improved.
It contains a clear description of the method of gastric integrated acidity
and a detailed discussion on its potential clinical relevance.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests
Please review this paper.
user
Reviewer's report
Title:Time Esophageal pH<4 Overestimates the Prevalence of Pathologic
Esophageal Reflux in Subjects with Gastroesophageal Reflux Disease Treated
with Proton Pump Inhibitors
Version: 3Date:17 April 2008
Reviewer: Martin Fein
Reviewer's report:
In response to my review the paper has been considerably improved.
It contains a clear description of the method of gastric integrated acidity
and a detailed discussion on its potential clinical relevance.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests
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