Title: The effectiveness of Radiotherapy and Transarterial Embolization for Advanced Gastric
Cancer Bleeding
Version: 2 Date: 15 Apr 2024
Reviewer's report:
Dear author,
the work entitled "Hemostatic Management in the Face of Inoperability: Evaluating
Radiotherapy and Transarterial Embolization for Advanced Gastric Cancer Bleeding" is an
interesting paper investigating the hemostatic outcomes of radiotherapy and embolization for
advanced gastric cancer.  I enjoyed reading the paper, but I think some points should be ruled
out and carefully reassessed:
title and introduction: make the title more concise finding a different formula, like "Effectiveness
of..". Try to be more synthetic in the introduction.
Methods and results: this work is a single-centre experience with heterogeneous protocols
comparing 19 vs 9 patients (small sample size). Hence, results should be carefully interpreted.
Laboratory data (like Hb) may be shown together with the median volumes of blood transfusions.
What was the histology of cancers? Were there present any Ln or distant metastases? Moreover,
please provide all the confidential intervals.
Discussion: given the retrospective nature of the design, it is not possible to act on the reasons
why a treatment was preferred over another one; however, I suggest you clarify this point
including them (operator preference/availability?).
On the other hand, despite the several limitations, the present study seems to be the first available
paper comparing the two techniques. You state that a judicious selection should be made in
choosing the type of treatment: try to deepen this point. Finally, suggest new frontiers for
implementation of this specific field.
Kind regards
Title: The effectiveness of Radiotherapy and Transarterial Embolization for Advanced Gastric
Cancer Bleeding
Version: 2 Date: 15 Apr 2024
Reviewer's report:
Dear author,
the work entitled "Hemostatic Management in the Face of Inoperability: Evaluating
Radiotherapy and Transarterial Embolization for Advanced Gastric Cancer Bleeding" is an
interesting paper investigating the hemostatic outcomes of radiotherapy and embolization for
advanced gastric cancer.  I enjoyed reading the paper, but I think some points should be ruled
out and carefully reassessed:
title and introduction: make the title more concise finding a different formula, like "Effectiveness
of..". Try to be more synthetic in the introduction.
Methods and results: this work is a single-centre experience with heterogeneous protocols
comparing 19 vs 9 patients (small sample size). Hence, results should be carefully interpreted.
Laboratory data (like Hb) may be shown together with the median volumes of blood transfusions.
What was the histology of cancers? Were there present any Ln or distant metastases? Moreover,
please provide all the confidential intervals.
Discussion: given the retrospective nature of the design, it is not possible to act on the reasons
why a treatment was preferred over another one; however, I suggest you clarify this point
including them (operator preference/availability?).
On the other hand, despite the several limitations, the present study seems to be the first available
paper comparing the two techniques. You state that a judicious selection should be made in
choosing the type of treatment: try to deepen this point. Finally, suggest new frontiers for
implementation of this specific field.
Kind regards
Please review this paper.
user
Title: The effectiveness of Radiotherapy and Transarterial Embolization for Advanced Gastric
Cancer Bleeding
Version: 2 Date: 15 Apr 2024
Reviewer's report:
Dear author,
the work entitled "Hemostatic Management in the Face of Inoperability: Evaluating
Radiotherapy and Transarterial Embolization for Advanced Gastric Cancer Bleeding" is an
interesting paper investigating the hemostatic outcomes of radiotherapy and embolization for
advanced gastric cancer.  I enjoyed reading the paper, but I think some points should be ruled
out and carefully reassessed:
title and introduction: make the title more concise finding a different formula, like "Effectiveness
of..". Try to be more synthetic in the introduction.
Methods and results: this work is a single-centre experience with heterogeneous protocols
comparing 19 vs 9 patients (small sample size). Hence, results should be carefully interpreted.
Laboratory data (like Hb) may be shown together with the median volumes of blood transfusions.
What was the histology of cancers? Were there present any Ln or distant metastases? Moreover,
please provide all the confidential intervals.
Discussion: given the retrospective nature of the design, it is not possible to act on the reasons
why a treatment was preferred over another one; however, I suggest you clarify this point
including them (operator preference/availability?).
On the other hand, despite the several limitations, the present study seems to be the first available
paper comparing the two techniques. You state that a judicious selection should be made in
choosing the type of treatment: try to deepen this point. Finally, suggest new frontiers for
implementation of this specific field.
Kind regards
assistant