Reviewer's report
Title:Reduced lymphocyte count as an early marker for secondary pancreatic
infection in acute pancreatitis
Version:2Date:9 June 2015
Reviewer: Jens M Mayer
Reviewer's report:
The authors have reviewed an impressive number of patients presenting with
acute pancreatitis within a relatively short period of time and restrospectively
examined the predictive value of several clinical and chemical parameters on the
development of secondary pancreatic infection. The goal of the study is clear and
the methods applied are absolutely adequate. It is remarkable that the authors
were able to recruit this large number of patients, this is only possible in a well
organized and clinically expert setting. The data seem genuine and
unmanipulated, I could find no inaccuracies or other signs of data
mismanagement and the result part is up to good scientific standards. The
discussion is well made and takes into account the most recent and relevant
publication on the examined issue. Also, it sticks to the findings of the study and
does not stride too far into theory or pathophysiology, which would not be
supported by the authors’ findings. There is no widespread discussion of the
limitations of the presented work, but considering that this is a clearly clinical
paper, this point is not really relevant. Title and abstract are adequate, the writing
is well done and the manuscript is easy to read and understand.
In summary, it was a pleasure to read and review this recommendable article and
I strongly support its publication in your prestigious magazine.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
I declare that I have no competing interests
Reviewer's report
Title:Reduced lymphocyte count as an early marker for secondary pancreatic
infection in acute pancreatitis
Version:2Date:9 June 2015
Reviewer: Jens M Mayer
Reviewer's report:
The authors have reviewed an impressive number of patients presenting with
acute pancreatitis within a relatively short period of time and restrospectively
examined the predictive value of several clinical and chemical parameters on the
development of secondary pancreatic infection. The goal of the study is clear and
the methods applied are absolutely adequate. It is remarkable that the authors
were able to recruit this large number of patients, this is only possible in a well
organized and clinically expert setting. The data seem genuine and
unmanipulated, I could find no inaccuracies or other signs of data
mismanagement and the result part is up to good scientific standards. The
discussion is well made and takes into account the most recent and relevant
publication on the examined issue. Also, it sticks to the findings of the study and
does not stride too far into theory or pathophysiology, which would not be
supported by the authors’ findings. There is no widespread discussion of the
limitations of the presented work, but considering that this is a clearly clinical
paper, this point is not really relevant. Title and abstract are adequate, the writing
is well done and the manuscript is easy to read and understand.
In summary, it was a pleasure to read and review this recommendable article and
I strongly support its publication in your prestigious magazine.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
I declare that I have no competing interests
Please review this paper.
user
Reviewer's report
Title:Reduced lymphocyte count as an early marker for secondary pancreatic
infection in acute pancreatitis
Version:2Date:9 June 2015
Reviewer: Jens M Mayer
Reviewer's report:
The authors have reviewed an impressive number of patients presenting with
acute pancreatitis within a relatively short period of time and restrospectively
examined the predictive value of several clinical and chemical parameters on the
development of secondary pancreatic infection. The goal of the study is clear and
the methods applied are absolutely adequate. It is remarkable that the authors
were able to recruit this large number of patients, this is only possible in a well
organized and clinically expert setting. The data seem genuine and
unmanipulated, I could find no inaccuracies or other signs of data
mismanagement and the result part is up to good scientific standards. The
discussion is well made and takes into account the most recent and relevant
publication on the examined issue. Also, it sticks to the findings of the study and
does not stride too far into theory or pathophysiology, which would not be
supported by the authors’ findings. There is no widespread discussion of the
limitations of the presented work, but considering that this is a clearly clinical
paper, this point is not really relevant. Title and abstract are adequate, the writing
is well done and the manuscript is easy to read and understand.
In summary, it was a pleasure to read and review this recommendable article and
I strongly support its publication in your prestigious magazine.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
I declare that I have no competing interests
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