Reviewer's report
Title:Rebleeding rate after capsule endoscopy for patients with obscure
gastrointestinal bleeding
Version: 1Date:14 February 2008
Reviewer: mark E. mcalindon
Reviewer's report:
Major 1: I am not absolutely clear if "therapeutic intervention" and "specific
medical therapy" are considered seperately - I think they are, but perhaps this
needs to be clarified further.
Major 2: One of the main messages is that therapeutic intervention reduces
rebleed rate, but there are no details about these two groups of patients. Perhaps
patients did not undergo intervention because they had significant co-morbidity
(eg advanced heart failure) and were on aspirin or anticoagulants. One would
expect that this kind of patient would be at high risk of rebleed. i.e. is it the
intervention that helps, or is it that those who do not undergo intervention are a
high risk group? This should be addressed.
What next?: Unable to decide on acceptance or rejection until the authors have
responded to the major compulsory revisions
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests.
Reviewer's report
Title:Rebleeding rate after capsule endoscopy for patients with obscure
gastrointestinal bleeding
Version: 1Date:14 February 2008
Reviewer: mark E. mcalindon
Reviewer's report:
Major 1: I am not absolutely clear if "therapeutic intervention" and "specific
medical therapy" are considered seperately - I think they are, but perhaps this
needs to be clarified further.
Major 2: One of the main messages is that therapeutic intervention reduces
rebleed rate, but there are no details about these two groups of patients. Perhaps
patients did not undergo intervention because they had significant co-morbidity
(eg advanced heart failure) and were on aspirin or anticoagulants. One would
expect that this kind of patient would be at high risk of rebleed. i.e. is it the
intervention that helps, or is it that those who do not undergo intervention are a
high risk group? This should be addressed.
What next?: Unable to decide on acceptance or rejection until the authors have
responded to the major compulsory revisions
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests.
Please review this paper.
user
Reviewer's report
Title:Rebleeding rate after capsule endoscopy for patients with obscure
gastrointestinal bleeding
Version: 1Date:14 February 2008
Reviewer: mark E. mcalindon
Reviewer's report:
Major 1: I am not absolutely clear if "therapeutic intervention" and "specific
medical therapy" are considered seperately - I think they are, but perhaps this
needs to be clarified further.
Major 2: One of the main messages is that therapeutic intervention reduces
rebleed rate, but there are no details about these two groups of patients. Perhaps
patients did not undergo intervention because they had significant co-morbidity
(eg advanced heart failure) and were on aspirin or anticoagulants. One would
expect that this kind of patient would be at high risk of rebleed. i.e. is it the
intervention that helps, or is it that those who do not undergo intervention are a
high risk group? This should be addressed.
What next?: Unable to decide on acceptance or rejection until the authors have
responded to the major compulsory revisions
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests.
assistant