Reviewer's report
Title:Effect of a multispecies probiotic supplement on quantity of irritable bowel
syndrome-related intestinal microbial phylotypes
Version: 2Date:8 June 2010
Reviewer: Robin Spiller
Reviewer's report:
The additional description of possible functional significance of the
Ruminococcus species adds value to the study. It may be that excessive mucus
degradation plays a part in the disruption of the barrier function reported in some
IBS patients.
It would be intresting to speculate what probiotics might achieve the same
reduction in Ruminococcus species
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: Yes, but I do not feel adequately qualified to assess the
statistics.
Declaration of competing interests:
I declare that I have no competing interests
Reviewer's report
Title:Effect of a multispecies probiotic supplement on quantity of irritable bowel
syndrome-related intestinal microbial phylotypes
Version: 2Date:8 June 2010
Reviewer: Robin Spiller
Reviewer's report:
The additional description of possible functional significance of the
Ruminococcus species adds value to the study. It may be that excessive mucus
degradation plays a part in the disruption of the barrier function reported in some
IBS patients.
It would be intresting to speculate what probiotics might achieve the same
reduction in Ruminococcus species
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: Yes, but I do not feel adequately qualified to assess the
statistics.
Declaration of competing interests:
I declare that I have no competing interests
Please review this paper.
user
Reviewer's report
Title:Effect of a multispecies probiotic supplement on quantity of irritable bowel
syndrome-related intestinal microbial phylotypes
Version: 2Date:8 June 2010
Reviewer: Robin Spiller
Reviewer's report:
The additional description of possible functional significance of the
Ruminococcus species adds value to the study. It may be that excessive mucus
degradation plays a part in the disruption of the barrier function reported in some
IBS patients.
It would be intresting to speculate what probiotics might achieve the same
reduction in Ruminococcus species
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: Yes, but I do not feel adequately qualified to assess the
statistics.
Declaration of competing interests:
I declare that I have no competing interests
assistant