Title: Different imaging techniques' diagnostic efficacy for Crohn's disease activity and external
validation and comparison of MDCTAs, SES-CD and IBUS-SAS
Version: 1 Date: 20 Jul 2024
Reviewer's report:
I am very pleased to have had the opportunity to review this manuscript.
This study evaluated the correlation between MDCT, SES-CD, IBUS, blood test findings, and
biomarkers in Crohn's disease. It was shown that these contribute to reflecting disease activity
in CD.
This study is not suitable for publication in this journal due to the following issues.
The word limit for abstracts in BMC gastroenterology has been exceeded. The authors should
submit their work in accordance with the basic guidelines.
This study was conducted with written informed consent through consent to participate, but it
is a retrospective study. Why could the authors not have made this a prospective study?
CD is a disease that involves abscesses. Were abscesses that could affect blood test findings
excluded? Were other infections also excluded?
The correlation coefficient between FC and imaging tests such as SES-CD is low. The reliability
of the endoscopic examination in this study is questionable.
The AUC results of the ROC analysis showed that SES-CD was lower than MDCT and IBUS.
Are these results correct? If true, this would greatly reduce the need for endoscopic evaluation.
Title: Different imaging techniques' diagnostic efficacy for Crohn's disease activity and external
validation and comparison of MDCTAs, SES-CD and IBUS-SAS
Version: 1 Date: 20 Jul 2024
Reviewer's report:
I am very pleased to have had the opportunity to review this manuscript.
This study evaluated the correlation between MDCT, SES-CD, IBUS, blood test findings, and
biomarkers in Crohn's disease. It was shown that these contribute to reflecting disease activity
in CD.
This study is not suitable for publication in this journal due to the following issues.
The word limit for abstracts in BMC gastroenterology has been exceeded. The authors should
submit their work in accordance with the basic guidelines.
This study was conducted with written informed consent through consent to participate, but it
is a retrospective study. Why could the authors not have made this a prospective study?
CD is a disease that involves abscesses. Were abscesses that could affect blood test findings
excluded? Were other infections also excluded?
The correlation coefficient between FC and imaging tests such as SES-CD is low. The reliability
of the endoscopic examination in this study is questionable.
The AUC results of the ROC analysis showed that SES-CD was lower than MDCT and IBUS.
Are these results correct? If true, this would greatly reduce the need for endoscopic evaluation.
Please review this paper.
user
Title: Different imaging techniques' diagnostic efficacy for Crohn's disease activity and external
validation and comparison of MDCTAs, SES-CD and IBUS-SAS
Version: 1 Date: 20 Jul 2024
Reviewer's report:
I am very pleased to have had the opportunity to review this manuscript.
This study evaluated the correlation between MDCT, SES-CD, IBUS, blood test findings, and
biomarkers in Crohn's disease. It was shown that these contribute to reflecting disease activity
in CD.
This study is not suitable for publication in this journal due to the following issues.
The word limit for abstracts in BMC gastroenterology has been exceeded. The authors should
submit their work in accordance with the basic guidelines.
This study was conducted with written informed consent through consent to participate, but it
is a retrospective study. Why could the authors not have made this a prospective study?
CD is a disease that involves abscesses. Were abscesses that could affect blood test findings
excluded? Were other infections also excluded?
The correlation coefficient between FC and imaging tests such as SES-CD is low. The reliability
of the endoscopic examination in this study is questionable.
The AUC results of the ROC analysis showed that SES-CD was lower than MDCT and IBUS.
Are these results correct? If true, this would greatly reduce the need for endoscopic evaluation.
assistant