Reviewer's report
Title:Dilemma of endoscopic features of solitary rectal ulcer syndrome.
Version: 2Date:22 April 2012
Reviewer: Alireza Keshtgar
Reviewer's report:
Major Compulsory revision
The authors should emphasise in the discussion that the neoplastic lesions of
adenoma and adenocarcinoma has been reported as an association with SRUS
and there is no established causal relationship in the literature.
Minor Essential Revisions
The authors should describe in methodology the criteria for diagnosis of acute
and chronic inflammation on histology.
The figures 6, 8 and 9 can be removed.
In the figure 7 the histology micrograph figures 7C and 7D have been mislabelled
as figures 10 and 11 in the manuscript.
The figure 10 should include markers to clearly demonstrate the finding of 'rectal
glands separated by splaying smooth muscle fibers and fibrosis', which is
referred to in the mislabelled figure 7C.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests.
Reviewer's report
Title:Dilemma of endoscopic features of solitary rectal ulcer syndrome.
Version: 2Date:22 April 2012
Reviewer: Alireza Keshtgar
Reviewer's report:
Major Compulsory revision
The authors should emphasise in the discussion that the neoplastic lesions of
adenoma and adenocarcinoma has been reported as an association with SRUS
and there is no established causal relationship in the literature.
Minor Essential Revisions
The authors should describe in methodology the criteria for diagnosis of acute
and chronic inflammation on histology.
The figures 6, 8 and 9 can be removed.
In the figure 7 the histology micrograph figures 7C and 7D have been mislabelled
as figures 10 and 11 in the manuscript.
The figure 10 should include markers to clearly demonstrate the finding of 'rectal
glands separated by splaying smooth muscle fibers and fibrosis', which is
referred to in the mislabelled figure 7C.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests.
Please review this paper.
user
Reviewer's report
Title:Dilemma of endoscopic features of solitary rectal ulcer syndrome.
Version: 2Date:22 April 2012
Reviewer: Alireza Keshtgar
Reviewer's report:
Major Compulsory revision
The authors should emphasise in the discussion that the neoplastic lesions of
adenoma and adenocarcinoma has been reported as an association with SRUS
and there is no established causal relationship in the literature.
Minor Essential Revisions
The authors should describe in methodology the criteria for diagnosis of acute
and chronic inflammation on histology.
The figures 6, 8 and 9 can be removed.
In the figure 7 the histology micrograph figures 7C and 7D have been mislabelled
as figures 10 and 11 in the manuscript.
The figure 10 should include markers to clearly demonstrate the finding of 'rectal
glands separated by splaying smooth muscle fibers and fibrosis', which is
referred to in the mislabelled figure 7C.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests.
assistant