Title: Esophageal cancer: a twenty-four-year experience at a tertiary care center with an
evaluation of the prognostic significance of the Neutrophil-Lymphocyte ratio
Version: 3 Date: 30 Oct 2023
Reviewer:  Shunji Endo
Reviewer's report:
There are few papers on esophageal cancer from the Middle East, so I think this is a valuable
epidemiological study.
I think that the following sentence is an important result; “After adjusting for age, gender, TNM
staging and grading, cox regression analysis showed that an increased NLR was a significant
predictor of mortality, with an adjusted hazard ratio of 1.095 (p=0.011).”, but I would like to
see a figure or table that visually appeals to this.
Title: Esophageal cancer: a twenty-four-year experience at a tertiary care center with an
evaluation of the prognostic significance of the Neutrophil-Lymphocyte ratio
Version: 3 Date: 30 Oct 2023
Reviewer:  Shunji Endo
Reviewer's report:
There are few papers on esophageal cancer from the Middle East, so I think this is a valuable
epidemiological study.
I think that the following sentence is an important result; “After adjusting for age, gender, TNM
staging and grading, cox regression analysis showed that an increased NLR was a significant
predictor of mortality, with an adjusted hazard ratio of 1.095 (p=0.011).”, but I would like to
see a figure or table that visually appeals to this.
Please review this paper.
user
Title: Esophageal cancer: a twenty-four-year experience at a tertiary care center with an
evaluation of the prognostic significance of the Neutrophil-Lymphocyte ratio
Version: 3 Date: 30 Oct 2023
Reviewer:  Shunji Endo
Reviewer's report:
There are few papers on esophageal cancer from the Middle East, so I think this is a valuable
epidemiological study.
I think that the following sentence is an important result; “After adjusting for age, gender, TNM
staging and grading, cox regression analysis showed that an increased NLR was a significant
predictor of mortality, with an adjusted hazard ratio of 1.095 (p=0.011).”, but I would like to
see a figure or table that visually appeals to this.
assistant