Title: Antimicrobial resistance in patients with decompensated liver cirrhosis and bacterial
infections in a tertiary center in Northern Germany
Version: 1 Date: 30 Apr 2021
Reviewer's report:
This is an interesting and important article about cirrhotic patients with bacterial infections.
However, I have some questions and suggestions to this study:
1) Because all of the enrolled cirrhotic patients have ascites, the world “ascites” should be listed
in the title of this article.
2) What is “BSI”? blood stream infection? It should be listed in the Abbreviations sections or
in the article.
3) In this study, the definition of SBP was “ # 500 nucleus containing cells/µl ascites fluid”.
Please provide the guidelines or articles as reference about this definition.
4) Pneumonia is also an important infection in cirrhotic patients. It is better to explain why
pneumonia was not analyzed in this study.
5) Using regression analysis method may provide more information in this study.
6) What is the mortality of the patients in the study  Infections are important issues in patients
with liver cirrhosis because of the high mortality. Could you provide this data in the article? If
not possible, please also mentioned that in the limitation part of the article.
Thanks!
Title: Antimicrobial resistance in patients with decompensated liver cirrhosis and bacterial
infections in a tertiary center in Northern Germany
Version: 1 Date: 30 Apr 2021
Reviewer's report:
This is an interesting and important article about cirrhotic patients with bacterial infections.
However, I have some questions and suggestions to this study:
1) Because all of the enrolled cirrhotic patients have ascites, the world “ascites” should be listed
in the title of this article.
2) What is “BSI”? blood stream infection? It should be listed in the Abbreviations sections or
in the article.
3) In this study, the definition of SBP was “ # 500 nucleus containing cells/µl ascites fluid”.
Please provide the guidelines or articles as reference about this definition.
4) Pneumonia is also an important infection in cirrhotic patients. It is better to explain why
pneumonia was not analyzed in this study.
5) Using regression analysis method may provide more information in this study.
6) What is the mortality of the patients in the study  Infections are important issues in patients
with liver cirrhosis because of the high mortality. Could you provide this data in the article? If
not possible, please also mentioned that in the limitation part of the article.
Thanks!
Please review this paper.
user
Title: Antimicrobial resistance in patients with decompensated liver cirrhosis and bacterial
infections in a tertiary center in Northern Germany
Version: 1 Date: 30 Apr 2021
Reviewer's report:
This is an interesting and important article about cirrhotic patients with bacterial infections.
However, I have some questions and suggestions to this study:
1) Because all of the enrolled cirrhotic patients have ascites, the world “ascites” should be listed
in the title of this article.
2) What is “BSI”? blood stream infection? It should be listed in the Abbreviations sections or
in the article.
3) In this study, the definition of SBP was “ # 500 nucleus containing cells/µl ascites fluid”.
Please provide the guidelines or articles as reference about this definition.
4) Pneumonia is also an important infection in cirrhotic patients. It is better to explain why
pneumonia was not analyzed in this study.
5) Using regression analysis method may provide more information in this study.
6) What is the mortality of the patients in the study  Infections are important issues in patients
with liver cirrhosis because of the high mortality. Could you provide this data in the article? If
not possible, please also mentioned that in the limitation part of the article.
Thanks!
assistant