Title: The effect of chewing gum on postoperative ileus after laparotomy for gastroduodenal
perforations: A randomized controlled trial.
Version: 2 Date: 17 Jun 2024
Reviewer:  Yoichi Nakagawa
Reviewer's report:
Thank you for your manuscript.
In the manuscript, the authors discuss the effect of chewing gum on postoperative ileus. The main
contribution of the paper is that gum chewing reduces postoperative ileus even after laparotomy
for gastroduodenal perforations. The authors made a good attempt to evaluate this clinical
question by a randomized controlled trial. This study area and methods are overlapped previous
study such as “Effect of chewing gum in reducing postoperative ileus after gastroduodenal
perforation peritonitis surgery: A prospective randomised controlled trial” by Sanjay Muwel,
et al.; however, I believe that this paper can contribute in some way to the postoperative
management of gastroduodenal perforations.
Minor comments
Table1
The authors present categorical variables as n (% in raw) in each group. It is just a matter
of preference, but I found the numbers presented as n (% in raw) a bit confusing. I would
recommend describing the numbers as n (% in each group). For example, Male 22 (85%)/Female
4 (15%) in chewing gum group.
Surgery
The authors provide the site of perforation at surgery, but I would recommend adding details of
the surgery, e.g. procedure (bowel resection, simple suture, omental patch closure, etc).
Title: The effect of chewing gum on postoperative ileus after laparotomy for gastroduodenal
perforations: A randomized controlled trial.
Version: 2 Date: 17 Jun 2024
Reviewer:  Yoichi Nakagawa
Reviewer's report:
Thank you for your manuscript.
In the manuscript, the authors discuss the effect of chewing gum on postoperative ileus. The main
contribution of the paper is that gum chewing reduces postoperative ileus even after laparotomy
for gastroduodenal perforations. The authors made a good attempt to evaluate this clinical
question by a randomized controlled trial. This study area and methods are overlapped previous
study such as “Effect of chewing gum in reducing postoperative ileus after gastroduodenal
perforation peritonitis surgery: A prospective randomised controlled trial” by Sanjay Muwel,
et al.; however, I believe that this paper can contribute in some way to the postoperative
management of gastroduodenal perforations.
Minor comments
Table1
The authors present categorical variables as n (% in raw) in each group. It is just a matter
of preference, but I found the numbers presented as n (% in raw) a bit confusing. I would
recommend describing the numbers as n (% in each group). For example, Male 22 (85%)/Female
4 (15%) in chewing gum group.
Surgery
The authors provide the site of perforation at surgery, but I would recommend adding details of
the surgery, e.g. procedure (bowel resection, simple suture, omental patch closure, etc).
Please review this paper.
user
Title: The effect of chewing gum on postoperative ileus after laparotomy for gastroduodenal
perforations: A randomized controlled trial.
Version: 2 Date: 17 Jun 2024
Reviewer:  Yoichi Nakagawa
Reviewer's report:
Thank you for your manuscript.
In the manuscript, the authors discuss the effect of chewing gum on postoperative ileus. The main
contribution of the paper is that gum chewing reduces postoperative ileus even after laparotomy
for gastroduodenal perforations. The authors made a good attempt to evaluate this clinical
question by a randomized controlled trial. This study area and methods are overlapped previous
study such as “Effect of chewing gum in reducing postoperative ileus after gastroduodenal
perforation peritonitis surgery: A prospective randomised controlled trial” by Sanjay Muwel,
et al.; however, I believe that this paper can contribute in some way to the postoperative
management of gastroduodenal perforations.
Minor comments
Table1
The authors present categorical variables as n (% in raw) in each group. It is just a matter
of preference, but I found the numbers presented as n (% in raw) a bit confusing. I would
recommend describing the numbers as n (% in each group). For example, Male 22 (85%)/Female
4 (15%) in chewing gum group.
Surgery
The authors provide the site of perforation at surgery, but I would recommend adding details of
the surgery, e.g. procedure (bowel resection, simple suture, omental patch closure, etc).
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