Title: Fatigue, pain and faecal incontinence in adult Inflammatory Bowel Disease patients and
the unmet need: a national cross-sectional survey
Version: 2 Date: 02 Nov 2024
Reviewer:  Panagiotis Tsibouris
Reviewer's report:
Abstract Numerical and p values in multivariated analysis should be presented Methods Did
a campagn preceeded posting questionnaires? What about minority inhabitants in NorthWest?
Were they excluded? Were treating physicians ( both GPs and specialists) involved in this
survey? Authors should mention that the survey represents a 7 day snapshot Was disease activity
or severity taken into consideration ?  Which depression and anxiety score was taken into
consideration since both of them could be affected by the disease? When mental illness was
diagnosed to be considered as preceeding IBD ? Which mental illnesses have been included?
Was dementia an exclusion criterion?  Results How many questionnaires were actualy sented
out from the 12500 initially allocated? Ones received were 8486 plus 5% with missing data or
refused to take part in the study it makes 8910. Because there is a male predominance in IBD
patients and the population of the study is predominantly female ( possibly because female tend
to respond more frequently in quality of life studies, did authors proceed in any adaptation?
Analysis in relation to disease activity and severity is missing Is it possible to be performed?
Title: Fatigue, pain and faecal incontinence in adult Inflammatory Bowel Disease patients and
the unmet need: a national cross-sectional survey
Version: 2 Date: 02 Nov 2024
Reviewer:  Panagiotis Tsibouris
Reviewer's report:
Abstract Numerical and p values in multivariated analysis should be presented Methods Did
a campagn preceeded posting questionnaires? What about minority inhabitants in NorthWest?
Were they excluded? Were treating physicians ( both GPs and specialists) involved in this
survey? Authors should mention that the survey represents a 7 day snapshot Was disease activity
or severity taken into consideration ?  Which depression and anxiety score was taken into
consideration since both of them could be affected by the disease? When mental illness was
diagnosed to be considered as preceeding IBD ? Which mental illnesses have been included?
Was dementia an exclusion criterion?  Results How many questionnaires were actualy sented
out from the 12500 initially allocated? Ones received were 8486 plus 5% with missing data or
refused to take part in the study it makes 8910. Because there is a male predominance in IBD
patients and the population of the study is predominantly female ( possibly because female tend
to respond more frequently in quality of life studies, did authors proceed in any adaptation?
Analysis in relation to disease activity and severity is missing Is it possible to be performed?
Please review this paper.
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Title: Fatigue, pain and faecal incontinence in adult Inflammatory Bowel Disease patients and
the unmet need: a national cross-sectional survey
Version: 2 Date: 02 Nov 2024
Reviewer:  Panagiotis Tsibouris
Reviewer's report:
Abstract Numerical and p values in multivariated analysis should be presented Methods Did
a campagn preceeded posting questionnaires? What about minority inhabitants in NorthWest?
Were they excluded? Were treating physicians ( both GPs and specialists) involved in this
survey? Authors should mention that the survey represents a 7 day snapshot Was disease activity
or severity taken into consideration ?  Which depression and anxiety score was taken into
consideration since both of them could be affected by the disease? When mental illness was
diagnosed to be considered as preceeding IBD ? Which mental illnesses have been included?
Was dementia an exclusion criterion?  Results How many questionnaires were actualy sented
out from the 12500 initially allocated? Ones received were 8486 plus 5% with missing data or
refused to take part in the study it makes 8910. Because there is a male predominance in IBD
patients and the population of the study is predominantly female ( possibly because female tend
to respond more frequently in quality of life studies, did authors proceed in any adaptation?
Analysis in relation to disease activity and severity is missing Is it possible to be performed?
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