Title: Transcatheter arterial chemoembolization alone versus combined with microwave
ablation for recurrent small hepatocellular carcinoma after resection: A retrospective
comparative study
Version: 3 Date: 01 Mar 2022
Reviewer's report:
To the authors:
“Transcatheter arterial chemoembolization alone versus combined with microwave ablation for
recurrent small hepatocellular carcinoma after resection: A retrospective comparative study”
My comments are as follows.
1. Please show the rationale whether hepatitis B be present or not.
2. Please show the rationale for setting the cut-off value of AFP to 400 ng/mL.
3. As a result, which treatment, MWA or RFA, do you think it is suitable after TACE?
4. You mentioned “TACE and TACE-MWA may lead to a similar OS in patients with recurrent
small HCC after resection. However, TACE-MWA shows a better tumor response at 1 month
and may prolong tumor PFS time”. How about as the first line treatment in patients with recurrent
small HCC, not after resection? Please explain your opinion.
I hope that my comments will be useful in improving the article.
Title: Transcatheter arterial chemoembolization alone versus combined with microwave
ablation for recurrent small hepatocellular carcinoma after resection: A retrospective
comparative study
Version: 3 Date: 01 Mar 2022
Reviewer's report:
To the authors:
“Transcatheter arterial chemoembolization alone versus combined with microwave ablation for
recurrent small hepatocellular carcinoma after resection: A retrospective comparative study”
My comments are as follows.
1. Please show the rationale whether hepatitis B be present or not.
2. Please show the rationale for setting the cut-off value of AFP to 400 ng/mL.
3. As a result, which treatment, MWA or RFA, do you think it is suitable after TACE?
4. You mentioned “TACE and TACE-MWA may lead to a similar OS in patients with recurrent
small HCC after resection. However, TACE-MWA shows a better tumor response at 1 month
and may prolong tumor PFS time”. How about as the first line treatment in patients with recurrent
small HCC, not after resection? Please explain your opinion.
I hope that my comments will be useful in improving the article.
Please review this paper.
user
Title: Transcatheter arterial chemoembolization alone versus combined with microwave
ablation for recurrent small hepatocellular carcinoma after resection: A retrospective
comparative study
Version: 3 Date: 01 Mar 2022
Reviewer's report:
To the authors:
“Transcatheter arterial chemoembolization alone versus combined with microwave ablation for
recurrent small hepatocellular carcinoma after resection: A retrospective comparative study”
My comments are as follows.
1. Please show the rationale whether hepatitis B be present or not.
2. Please show the rationale for setting the cut-off value of AFP to 400 ng/mL.
3. As a result, which treatment, MWA or RFA, do you think it is suitable after TACE?
4. You mentioned “TACE and TACE-MWA may lead to a similar OS in patients with recurrent
small HCC after resection. However, TACE-MWA shows a better tumor response at 1 month
and may prolong tumor PFS time”. How about as the first line treatment in patients with recurrent
small HCC, not after resection? Please explain your opinion.
I hope that my comments will be useful in improving the article.
assistant