Reviewer's report
Title:Autoimmune pancreatitis with colonic stenosis: an unusual complication
and atypical pancreatographic finding
Version:2Date:20 July 2014
Reviewer: Luca Frulloni
Reviewer's report:
The paper is interisting since describes a case of AIP involving colon, with
stricture, and responding to steroid therapy. I have the following remarks:
1. The case cannot be classified as definitive type 1 AIP, since it has Response
to steroids and level 1 Serology, level 2 ductal and level 2 parenchimal. However,
the very high levels of serum IgG4 indicates a type 1 AIP. In the discussion
section the Author can stress the lack of ICDC in this case before steroid
treatment.
2. the Authors did not report the dosage of steroids.
3. MR and MRCP may evaluate the MPD dilation upstream the stenosis not
evaluable by ERCP, and the length of stenosis. Indeed, a long stenosis (> 1/3)
my let to a definitive diagnosis of type 1 AIP. MR and MRCP is included in ICDC.
This should be discussed.
Level of interest: An article of importance in its field
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
I declare that I have no competing interests
Reviewer's report
Title:Autoimmune pancreatitis with colonic stenosis: an unusual complication
and atypical pancreatographic finding
Version:2Date:20 July 2014
Reviewer: Luca Frulloni
Reviewer's report:
The paper is interisting since describes a case of AIP involving colon, with
stricture, and responding to steroid therapy. I have the following remarks:
1. The case cannot be classified as definitive type 1 AIP, since it has Response
to steroids and level 1 Serology, level 2 ductal and level 2 parenchimal. However,
the very high levels of serum IgG4 indicates a type 1 AIP. In the discussion
section the Author can stress the lack of ICDC in this case before steroid
treatment.
2. the Authors did not report the dosage of steroids.
3. MR and MRCP may evaluate the MPD dilation upstream the stenosis not
evaluable by ERCP, and the length of stenosis. Indeed, a long stenosis (> 1/3)
my let to a definitive diagnosis of type 1 AIP. MR and MRCP is included in ICDC.
This should be discussed.
Level of interest: An article of importance in its field
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
I declare that I have no competing interests
Please review this paper.
user
Reviewer's report
Title:Autoimmune pancreatitis with colonic stenosis: an unusual complication
and atypical pancreatographic finding
Version:2Date:20 July 2014
Reviewer: Luca Frulloni
Reviewer's report:
The paper is interisting since describes a case of AIP involving colon, with
stricture, and responding to steroid therapy. I have the following remarks:
1. The case cannot be classified as definitive type 1 AIP, since it has Response
to steroids and level 1 Serology, level 2 ductal and level 2 parenchimal. However,
the very high levels of serum IgG4 indicates a type 1 AIP. In the discussion
section the Author can stress the lack of ICDC in this case before steroid
treatment.
2. the Authors did not report the dosage of steroids.
3. MR and MRCP may evaluate the MPD dilation upstream the stenosis not
evaluable by ERCP, and the length of stenosis. Indeed, a long stenosis (> 1/3)
my let to a definitive diagnosis of type 1 AIP. MR and MRCP is included in ICDC.
This should be discussed.
Level of interest: An article of importance in its field
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
I declare that I have no competing interests
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