Reviewer's report 
 Septic thrombophlebitis of the superior mesenteric vein and multiple liver abscesses in a patient with Title: 
Crohn`s disease at onset. 
 3  14 February 2007 Version: Date: 
 Alessandro Fichera Reviewer: 
Reviewer's report: 
General 
The paper is significantly improved but, there are still some changes that need to be made, mostly of the English language. ------------------------------------------------------------------------------- 
Major Compulsory Revisions (that the author must respond to before a decision on publication can be 
reached) None ------------------------------------------------------------------------------- 
Minor Essential Revisions (such as missing labels on figures, or the wrong use of a term, which the author 
can be trusted to correct) 
In the Case Report, the first sentence that reads: “A 25-year-old white male smoker patient was admitted to 
our hospital after due to fever and right lower quadrant abdominal pain” “after” should be eliminated. 
In several places “patients” is spelled “pacients”. That should be corrected. The use of the abbreviation CD 
for Crohn’s disease is not used throughout the paper and that should be corrected. 
Although it is important and interesting to know the dose of prednisone according to the body weight, I think 
that the overall dose should be mentioned when describing the case report. 
In the Case Report, the sentence that reads: “the time he continued on his medication of 5mg of prednisone 
per day” should read: “At the time he was still taking 5mg of prednisone by mouth per day”. 
At the end of the Case Report, a brief discussion on postoperative medical management following his 
discharge should be mentioned. 
In the Discussion, at the end of the first paragraph, the first sentence that reads: “We report a case of a 
young man in which said association was confirmed and was treated successfully with conservative therapy” should be changed to “A reported case of a young man with pylephlebitis and liver abscesses 
associated with Crohn’s disease was treated successfully with conservative therapy followed by surgery. 
In the Discussion, again, several times patient is spelled with a “c” and Crohn’s disease is not abbreviated 
throughout the Discussion. 
The new figure is very helpful in understanding the course of the patient. Overall, I think the paper is 
significantly improved and after these minor grammatical changes should be accepted for publication. 
------------------------------------------------------------------------------- 
Discretionary Revisions (which the author can choose to ignore) 
None 
 Accept after minor essential revisions What next?: 
 An article of importance in its field Level of interest: 
 Needs some language corrections before being published Quality of written English: 
 No, the manuscript does not need to be seen by a statistician. Statistical review: 
Declaration of competing interests: 
'I declare that I have no competing interests' 
Reviewer's report 
 Septic thrombophlebitis of the superior mesenteric vein and multiple liver abscesses in a patient with Title: 
Crohn`s disease at onset. 
 3  14 February 2007 Version: Date: 
 Alessandro Fichera Reviewer: 
Reviewer's report: 
General 
The paper is significantly improved but, there are still some changes that need to be made, mostly of the English language. ------------------------------------------------------------------------------- 
Major Compulsory Revisions (that the author must respond to before a decision on publication can be 
reached) None ------------------------------------------------------------------------------- 
Minor Essential Revisions (such as missing labels on figures, or the wrong use of a term, which the author 
can be trusted to correct) 
In the Case Report, the first sentence that reads: “A 25-year-old white male smoker patient was admitted to 
our hospital after due to fever and right lower quadrant abdominal pain” “after” should be eliminated. 
In several places “patients” is spelled “pacients”. That should be corrected. The use of the abbreviation CD 
for Crohn’s disease is not used throughout the paper and that should be corrected. 
Although it is important and interesting to know the dose of prednisone according to the body weight, I think 
that the overall dose should be mentioned when describing the case report. 
In the Case Report, the sentence that reads: “the time he continued on his medication of 5mg of prednisone 
per day” should read: “At the time he was still taking 5mg of prednisone by mouth per day”. 
At the end of the Case Report, a brief discussion on postoperative medical management following his 
discharge should be mentioned. 
In the Discussion, at the end of the first paragraph, the first sentence that reads: “We report a case of a 
young man in which said association was confirmed and was treated successfully with conservative therapy” should be changed to “A reported case of a young man with pylephlebitis and liver abscesses 
associated with Crohn’s disease was treated successfully with conservative therapy followed by surgery. 
In the Discussion, again, several times patient is spelled with a “c” and Crohn’s disease is not abbreviated 
throughout the Discussion. 
The new figure is very helpful in understanding the course of the patient. Overall, I think the paper is 
significantly improved and after these minor grammatical changes should be accepted for publication. 
------------------------------------------------------------------------------- 
Discretionary Revisions (which the author can choose to ignore) 
None 
 Accept after minor essential revisions What next?: 
 An article of importance in its field Level of interest: 
 Needs some language corrections before being published Quality of written English: 
 No, the manuscript does not need to be seen by a statistician. Statistical review: 
Declaration of competing interests: 
'I declare that I have no competing interests' 
Please review this paper.
user
Reviewer's report 
 Septic thrombophlebitis of the superior mesenteric vein and multiple liver abscesses in a patient with Title: 
Crohn`s disease at onset. 
 3  14 February 2007 Version: Date: 
 Alessandro Fichera Reviewer: 
Reviewer's report: 
General 
The paper is significantly improved but, there are still some changes that need to be made, mostly of the English language. ------------------------------------------------------------------------------- 
Major Compulsory Revisions (that the author must respond to before a decision on publication can be 
reached) None ------------------------------------------------------------------------------- 
Minor Essential Revisions (such as missing labels on figures, or the wrong use of a term, which the author 
can be trusted to correct) 
In the Case Report, the first sentence that reads: “A 25-year-old white male smoker patient was admitted to 
our hospital after due to fever and right lower quadrant abdominal pain” “after” should be eliminated. 
In several places “patients” is spelled “pacients”. That should be corrected. The use of the abbreviation CD 
for Crohn’s disease is not used throughout the paper and that should be corrected. 
Although it is important and interesting to know the dose of prednisone according to the body weight, I think 
that the overall dose should be mentioned when describing the case report. 
In the Case Report, the sentence that reads: “the time he continued on his medication of 5mg of prednisone 
per day” should read: “At the time he was still taking 5mg of prednisone by mouth per day”. 
At the end of the Case Report, a brief discussion on postoperative medical management following his 
discharge should be mentioned. 
In the Discussion, at the end of the first paragraph, the first sentence that reads: “We report a case of a 
young man in which said association was confirmed and was treated successfully with conservative therapy” should be changed to “A reported case of a young man with pylephlebitis and liver abscesses 
associated with Crohn’s disease was treated successfully with conservative therapy followed by surgery. 
In the Discussion, again, several times patient is spelled with a “c” and Crohn’s disease is not abbreviated 
throughout the Discussion. 
The new figure is very helpful in understanding the course of the patient. Overall, I think the paper is 
significantly improved and after these minor grammatical changes should be accepted for publication. 
------------------------------------------------------------------------------- 
Discretionary Revisions (which the author can choose to ignore) 
None 
 Accept after minor essential revisions What next?: 
 An article of importance in its field Level of interest: 
 Needs some language corrections before being published Quality of written English: 
 No, the manuscript does not need to be seen by a statistician. Statistical review: 
Declaration of competing interests: 
'I declare that I have no competing interests' 
assistant