Title: Autoimmune Liver Diseases, Autoantibodies, and Their Associations and liver disease
outcome, a single- center Retrospective Study heir Associations and liver disease outcome, a
single-center Retrospective Study
Version: 6 Date: 06 Feb 2025
Reviewer's report:
Mohammad et al. investigated the association between autoimmune liver disease (AILD),
autoantibodies, systemic rheumatic diseases, and prognosis. However, several concerns need to
be addressed in this article:
1.The sections on “Introduction” and “Discussion” are too long. These sections need to be more
concise.
2.A flow chart of this study is recommended.
3.It is unclear whether the authors used statistical software. If they did, it should be indicated
in the “Methods” section.
4.It is unclear whether the authors used a two-tailed P-value in this study.
5.In Table 4, the authors compared liver function indicators in AILD patients. They noted that
“Liver function data were extracted from laboratory tests taken close to the data collection
period.” However, liver function results may be influenced by treatment. Therefore, more
detailed treatment information for the included AILD patients should be provided.
6.Many studies have revealed that genetic factors may be associated with autoimmune diseases.
It is recommended that the authors discuss the association between AILD and systemic
rheumatic diseases from a genetic perspective.
Title: Autoimmune Liver Diseases, Autoantibodies, and Their Associations and liver disease
outcome, a single- center Retrospective Study heir Associations and liver disease outcome, a
single-center Retrospective Study
Version: 6 Date: 06 Feb 2025
Reviewer's report:
Mohammad et al. investigated the association between autoimmune liver disease (AILD),
autoantibodies, systemic rheumatic diseases, and prognosis. However, several concerns need to
be addressed in this article:
1.The sections on “Introduction” and “Discussion” are too long. These sections need to be more
concise.
2.A flow chart of this study is recommended.
3.It is unclear whether the authors used statistical software. If they did, it should be indicated
in the “Methods” section.
4.It is unclear whether the authors used a two-tailed P-value in this study.
5.In Table 4, the authors compared liver function indicators in AILD patients. They noted that
“Liver function data were extracted from laboratory tests taken close to the data collection
period.” However, liver function results may be influenced by treatment. Therefore, more
detailed treatment information for the included AILD patients should be provided.
6.Many studies have revealed that genetic factors may be associated with autoimmune diseases.
It is recommended that the authors discuss the association between AILD and systemic
rheumatic diseases from a genetic perspective.
Please review this paper.
user
Title: Autoimmune Liver Diseases, Autoantibodies, and Their Associations and liver disease
outcome, a single- center Retrospective Study heir Associations and liver disease outcome, a
single-center Retrospective Study
Version: 6 Date: 06 Feb 2025
Reviewer's report:
Mohammad et al. investigated the association between autoimmune liver disease (AILD),
autoantibodies, systemic rheumatic diseases, and prognosis. However, several concerns need to
be addressed in this article:
1.The sections on “Introduction” and “Discussion” are too long. These sections need to be more
concise.
2.A flow chart of this study is recommended.
3.It is unclear whether the authors used statistical software. If they did, it should be indicated
in the “Methods” section.
4.It is unclear whether the authors used a two-tailed P-value in this study.
5.In Table 4, the authors compared liver function indicators in AILD patients. They noted that
“Liver function data were extracted from laboratory tests taken close to the data collection
period.” However, liver function results may be influenced by treatment. Therefore, more
detailed treatment information for the included AILD patients should be provided.
6.Many studies have revealed that genetic factors may be associated with autoimmune diseases.
It is recommended that the authors discuss the association between AILD and systemic
rheumatic diseases from a genetic perspective.
assistant