Title: The influence of subjective well-being on anxiety, depression and quality of life in patients
with functional dyspepsia
Version: 2 Date: 21 Mar 2025
Reviewer's report:
Mental Health History and Medication Use
- It would be relevant to know whether data on participants' mental health history and medication
use were collected, especially regarding antidepressants. Since these drugs are sometimes
prescribed for managing functional dyspepsia symptoms, they could introduce bias in the
interpretation of the questionnaires. Similarly, it would be useful to consider probiotic use,
as their relationship with neurotransmitter production (such as serotonin and GABA) could
influence patients’ mood. If these data were not collected, it is recommended to mention this
as a limitation of the study.
Table Formatting
- It is suggested to standardize the font size across all tables to improve clarity and presentation.
Correction in Diagnostic Criteria Terminology
- In the text, the diagnostic criteria are referred to as "Roman", whereas the correct term is
"Rome", without the final "n".
Precision in Objective Formulation
- The study’s objective states that it aims to "examine the impact of subjective well-being
(SWB) on anxiety, depression, symptom severity, and quality of life in patients with functional
dyspepsia." However, since the study design is cross-sectional, it does not allow for causal
inference. It is recommended to replace the term "impact" with "association" or "relationship,"
as these terms are more appropriate for this type of study.
- In this same regard, the abstract currently states that SWB "affects" the severity of dyspepsia,
anxiety, and depression, and "improves" quality of life. However, since there is no data to
establish causality, it is recommended to rephrase this statement to reflect a relationship rather
than a causal effect. In the manuscript, the conclusion is appropriately stated, so this change is
only necessary in the abstract.
- Congratulations on this excellent work. It is a valuable study that provides relevant insights
into subjective well-being and its relationship with functional dyspepsia.
Title: The influence of subjective well-being on anxiety, depression and quality of life in patients
with functional dyspepsia
Version: 2 Date: 21 Mar 2025
Reviewer's report:
Mental Health History and Medication Use
- It would be relevant to know whether data on participants' mental health history and medication
use were collected, especially regarding antidepressants. Since these drugs are sometimes
prescribed for managing functional dyspepsia symptoms, they could introduce bias in the
interpretation of the questionnaires. Similarly, it would be useful to consider probiotic use,
as their relationship with neurotransmitter production (such as serotonin and GABA) could
influence patients’ mood. If these data were not collected, it is recommended to mention this
as a limitation of the study.
Table Formatting
- It is suggested to standardize the font size across all tables to improve clarity and presentation.
Correction in Diagnostic Criteria Terminology
- In the text, the diagnostic criteria are referred to as "Roman", whereas the correct term is
"Rome", without the final "n".
Precision in Objective Formulation
- The study’s objective states that it aims to "examine the impact of subjective well-being
(SWB) on anxiety, depression, symptom severity, and quality of life in patients with functional
dyspepsia." However, since the study design is cross-sectional, it does not allow for causal
inference. It is recommended to replace the term "impact" with "association" or "relationship,"
as these terms are more appropriate for this type of study.
- In this same regard, the abstract currently states that SWB "affects" the severity of dyspepsia,
anxiety, and depression, and "improves" quality of life. However, since there is no data to
establish causality, it is recommended to rephrase this statement to reflect a relationship rather
than a causal effect. In the manuscript, the conclusion is appropriately stated, so this change is
only necessary in the abstract.
- Congratulations on this excellent work. It is a valuable study that provides relevant insights
into subjective well-being and its relationship with functional dyspepsia.
Please review this paper.
user
Title: The influence of subjective well-being on anxiety, depression and quality of life in patients
with functional dyspepsia
Version: 2 Date: 21 Mar 2025
Reviewer's report:
Mental Health History and Medication Use
- It would be relevant to know whether data on participants' mental health history and medication
use were collected, especially regarding antidepressants. Since these drugs are sometimes
prescribed for managing functional dyspepsia symptoms, they could introduce bias in the
interpretation of the questionnaires. Similarly, it would be useful to consider probiotic use,
as their relationship with neurotransmitter production (such as serotonin and GABA) could
influence patients’ mood. If these data were not collected, it is recommended to mention this
as a limitation of the study.
Table Formatting
- It is suggested to standardize the font size across all tables to improve clarity and presentation.
Correction in Diagnostic Criteria Terminology
- In the text, the diagnostic criteria are referred to as "Roman", whereas the correct term is
"Rome", without the final "n".
Precision in Objective Formulation
- The study’s objective states that it aims to "examine the impact of subjective well-being
(SWB) on anxiety, depression, symptom severity, and quality of life in patients with functional
dyspepsia." However, since the study design is cross-sectional, it does not allow for causal
inference. It is recommended to replace the term "impact" with "association" or "relationship,"
as these terms are more appropriate for this type of study.
- In this same regard, the abstract currently states that SWB "affects" the severity of dyspepsia,
anxiety, and depression, and "improves" quality of life. However, since there is no data to
establish causality, it is recommended to rephrase this statement to reflect a relationship rather
than a causal effect. In the manuscript, the conclusion is appropriately stated, so this change is
only necessary in the abstract.
- Congratulations on this excellent work. It is a valuable study that provides relevant insights
into subjective well-being and its relationship with functional dyspepsia.
assistant