Title: The role of marital status in gallbladder cancer: a real-world competing risk analysis
Version: 0 Date: 03 Jun 2024
Reviewer's report:
Thank you for the opportunity to review the original research article entitled “The role of
marital status in gallbladder cancer: a real-world competing risk analysis” submitted to “BMC
Gastroenterology” for consideration for publication.
There are some issues with the entire article, and I have the following suggestion:
1.The author needs to add a flowchart of the validation cohort screening process.
2."From 2010 to 2015, relevant patient data was extracted from the SEER 18 Regs Custom Data
Set." Why not expand the selection of patient years in order to increase the sample size?
3.Patients with incomplete demographic, clinic-pathological, therapeutic, or follow-up data were
excluded in this study. The reason for the presence of the "unk" classification in tumor size in
Table 1 still remains unclear.
4.There are inconsistencies in the descriptions. ”An additional independent analysis was
undertaken, wherein patients were randomly assigned to two groups for the development of a
prognostic model: a training cohort (50%, n = 1597) and a validation cohort (50%, n = 1596).”
In fig 1, Training cohort = 1091, validation cohort = 1091.
5.How was the sample size of the external validation cohort determined?
Title: The role of marital status in gallbladder cancer: a real-world competing risk analysis
Version: 0 Date: 03 Jun 2024
Reviewer's report:
Thank you for the opportunity to review the original research article entitled “The role of
marital status in gallbladder cancer: a real-world competing risk analysis” submitted to “BMC
Gastroenterology” for consideration for publication.
There are some issues with the entire article, and I have the following suggestion:
1.The author needs to add a flowchart of the validation cohort screening process.
2."From 2010 to 2015, relevant patient data was extracted from the SEER 18 Regs Custom Data
Set." Why not expand the selection of patient years in order to increase the sample size?
3.Patients with incomplete demographic, clinic-pathological, therapeutic, or follow-up data were
excluded in this study. The reason for the presence of the "unk" classification in tumor size in
Table 1 still remains unclear.
4.There are inconsistencies in the descriptions. ”An additional independent analysis was
undertaken, wherein patients were randomly assigned to two groups for the development of a
prognostic model: a training cohort (50%, n = 1597) and a validation cohort (50%, n = 1596).”
In fig 1, Training cohort = 1091, validation cohort = 1091.
5.How was the sample size of the external validation cohort determined?
Please review this paper.
user
Title: The role of marital status in gallbladder cancer: a real-world competing risk analysis
Version: 0 Date: 03 Jun 2024
Reviewer's report:
Thank you for the opportunity to review the original research article entitled “The role of
marital status in gallbladder cancer: a real-world competing risk analysis” submitted to “BMC
Gastroenterology” for consideration for publication.
There are some issues with the entire article, and I have the following suggestion:
1.The author needs to add a flowchart of the validation cohort screening process.
2."From 2010 to 2015, relevant patient data was extracted from the SEER 18 Regs Custom Data
Set." Why not expand the selection of patient years in order to increase the sample size?
3.Patients with incomplete demographic, clinic-pathological, therapeutic, or follow-up data were
excluded in this study. The reason for the presence of the "unk" classification in tumor size in
Table 1 still remains unclear.
4.There are inconsistencies in the descriptions. ”An additional independent analysis was
undertaken, wherein patients were randomly assigned to two groups for the development of a
prognostic model: a training cohort (50%, n = 1597) and a validation cohort (50%, n = 1596).”
In fig 1, Training cohort = 1091, validation cohort = 1091.
5.How was the sample size of the external validation cohort determined?
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