Title: Liver histology pattern of young patients with inactive chronic hepatitis B virus infection
from a Hospital in South West Nigeria
Version: 5 Date: 02 Oct 2024
Reviewer's report:
Abstract:
"Thirty-nine (44.3%) had significant necroinflammation and fibrosis on histology, 19 (21.6%)
of whom had necroinflammation only and 13(14.8%) had combined necroinflammation and
fibrosis."
This should read "Thirty-nine (44.3%) had significant necroinflammation and/or fibrosis...."
Background:
Please put a NUMERICAL value for ALT ULN for males and females as per SOGHIN.
Results:
"Sixty three(92.6%) patients who had APRI score of < 0.5 and FIB 4 score of < 1.45 were
found to have corresponding no to mild fibrosis on histology. Three participants with FIB 4
score of > 1.45 had evidence of significant fibrosis on histology however, seventeen (85%)
participants with no fibrosis or mild fibrosis using both the APRI and FIB 4 score were found
to have significant fibrosis on histology. "
Indicate what the denominator is. Eg 63/68 etc
The rest of article:
Please do a thorough review for language and grammar.
Title: Liver histology pattern of young patients with inactive chronic hepatitis B virus infection
from a Hospital in South West Nigeria
Version: 5 Date: 02 Oct 2024
Reviewer's report:
Abstract:
"Thirty-nine (44.3%) had significant necroinflammation and fibrosis on histology, 19 (21.6%)
of whom had necroinflammation only and 13(14.8%) had combined necroinflammation and
fibrosis."
This should read "Thirty-nine (44.3%) had significant necroinflammation and/or fibrosis...."
Background:
Please put a NUMERICAL value for ALT ULN for males and females as per SOGHIN.
Results:
"Sixty three(92.6%) patients who had APRI score of < 0.5 and FIB 4 score of < 1.45 were
found to have corresponding no to mild fibrosis on histology. Three participants with FIB 4
score of > 1.45 had evidence of significant fibrosis on histology however, seventeen (85%)
participants with no fibrosis or mild fibrosis using both the APRI and FIB 4 score were found
to have significant fibrosis on histology. "
Indicate what the denominator is. Eg 63/68 etc
The rest of article:
Please do a thorough review for language and grammar.
Please review this paper.
user
Title: Liver histology pattern of young patients with inactive chronic hepatitis B virus infection
from a Hospital in South West Nigeria
Version: 5 Date: 02 Oct 2024
Reviewer's report:
Abstract:
"Thirty-nine (44.3%) had significant necroinflammation and fibrosis on histology, 19 (21.6%)
of whom had necroinflammation only and 13(14.8%) had combined necroinflammation and
fibrosis."
This should read "Thirty-nine (44.3%) had significant necroinflammation and/or fibrosis...."
Background:
Please put a NUMERICAL value for ALT ULN for males and females as per SOGHIN.
Results:
"Sixty three(92.6%) patients who had APRI score of < 0.5 and FIB 4 score of < 1.45 were
found to have corresponding no to mild fibrosis on histology. Three participants with FIB 4
score of > 1.45 had evidence of significant fibrosis on histology however, seventeen (85%)
participants with no fibrosis or mild fibrosis using both the APRI and FIB 4 score were found
to have significant fibrosis on histology. "
Indicate what the denominator is. Eg 63/68 etc
The rest of article:
Please do a thorough review for language and grammar.
assistant