Title: Exploring the Association Between Dietary Fiber Intake and Hepatic Steatosis: Insights
from NHANES
Version: 0 Date: 15 Apr 2024
Reviewer's report:
The authors present data from an observational study, investigating the association between fiber
intake and NAFLD.
The overall rationale is transparent, even though neither methods, topic or findings are novel.
The entire analysis is confirmatory.
Introduction: Fine.
Methods: Fine.
How did you define "high cholesterol levels"? The cut-offs differ by overall CVD risk status.
Results: Fine.
Please use adequate decimals according to raw data precision (e.g. WC with one decimal, liver
enzymes without...).
Discussion: You discovered huge differences of fiber-NAFLD associations between sexes, age
groups and ethnicities, with strata showing linear, inverse quadratic or wave-wise patterns.
Please clarify this heterogeneity more thoroughly.
Title: Exploring the Association Between Dietary Fiber Intake and Hepatic Steatosis: Insights
from NHANES
Version: 0 Date: 15 Apr 2024
Reviewer's report:
The authors present data from an observational study, investigating the association between fiber
intake and NAFLD.
The overall rationale is transparent, even though neither methods, topic or findings are novel.
The entire analysis is confirmatory.
Introduction: Fine.
Methods: Fine.
How did you define "high cholesterol levels"? The cut-offs differ by overall CVD risk status.
Results: Fine.
Please use adequate decimals according to raw data precision (e.g. WC with one decimal, liver
enzymes without...).
Discussion: You discovered huge differences of fiber-NAFLD associations between sexes, age
groups and ethnicities, with strata showing linear, inverse quadratic or wave-wise patterns.
Please clarify this heterogeneity more thoroughly.
Please review this paper.
user
Title: Exploring the Association Between Dietary Fiber Intake and Hepatic Steatosis: Insights
from NHANES
Version: 0 Date: 15 Apr 2024
Reviewer's report:
The authors present data from an observational study, investigating the association between fiber
intake and NAFLD.
The overall rationale is transparent, even though neither methods, topic or findings are novel.
The entire analysis is confirmatory.
Introduction: Fine.
Methods: Fine.
How did you define "high cholesterol levels"? The cut-offs differ by overall CVD risk status.
Results: Fine.
Please use adequate decimals according to raw data precision (e.g. WC with one decimal, liver
enzymes without...).
Discussion: You discovered huge differences of fiber-NAFLD associations between sexes, age
groups and ethnicities, with strata showing linear, inverse quadratic or wave-wise patterns.
Please clarify this heterogeneity more thoroughly.
assistant