Reviewer's report
Title:Modified endoscopic submucosal dissection with enucleation for treatment
of gastric subepithelial tumors originating from the muscularis propria layer
Version: 1Date:23 May 2012
Reviewer: Seok-Reyol Choi
Reviewer's report:
This paper described the Modified endoscopic submucosal dissection used for
enucleation of gastric subepithelial tumors originating from the muscularis propria
layer. This kind of concept is not noble, but this procedure is not yet widely
accepted. Thus, this paper has values to contribute the advent of endoscopic
procedure for exploring subepithelial tumors.
I would like to point out three major revisions.
1. Page 7 and Figures. I do not understand the modified ESD exactly. What is
the transverse incision exactly? Longitudinal incision and transverse incision
makes cross shape incision? The Figure 1d does not show cross-shape incision.
I think not a picture but a simple illustration will explain this procedure more
properly. Please insert an illustration that explains the modified ESD, especially
two incision lines.
2. According to result, authors removed three tumors at fundus. As all
endoscopists know, it is not easy to remove EGC and SMT at fundus. Please
describe more how to remove those three lesions in method or discussion.
3. One of the important issues in this kind of procedures is that we could not
evaluate the resection margin. Practitioners can enucleate the SMT, but they are
not able to check whether the resection margin is clear or not pathologically. In
this matter, I would like to listen to authors’ opinion. So called endoscopic
complete enucleation can guarantee pathologic complete resection? Please
describe to this in method and discussion.
I raised a few questions to the authors. However, I think that the authors did very
good job. They handled subtle big SMTs which might need surgery. They
preserved the function of the stomach with successful enucleation of SMTs.
Furthermore, they exactly diagnosed the property of tumors.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests
Reviewer's report
Title:Modified endoscopic submucosal dissection with enucleation for treatment
of gastric subepithelial tumors originating from the muscularis propria layer
Version: 1Date:23 May 2012
Reviewer: Seok-Reyol Choi
Reviewer's report:
This paper described the Modified endoscopic submucosal dissection used for
enucleation of gastric subepithelial tumors originating from the muscularis propria
layer. This kind of concept is not noble, but this procedure is not yet widely
accepted. Thus, this paper has values to contribute the advent of endoscopic
procedure for exploring subepithelial tumors.
I would like to point out three major revisions.
1. Page 7 and Figures. I do not understand the modified ESD exactly. What is
the transverse incision exactly? Longitudinal incision and transverse incision
makes cross shape incision? The Figure 1d does not show cross-shape incision.
I think not a picture but a simple illustration will explain this procedure more
properly. Please insert an illustration that explains the modified ESD, especially
two incision lines.
2. According to result, authors removed three tumors at fundus. As all
endoscopists know, it is not easy to remove EGC and SMT at fundus. Please
describe more how to remove those three lesions in method or discussion.
3. One of the important issues in this kind of procedures is that we could not
evaluate the resection margin. Practitioners can enucleate the SMT, but they are
not able to check whether the resection margin is clear or not pathologically. In
this matter, I would like to listen to authors’ opinion. So called endoscopic
complete enucleation can guarantee pathologic complete resection? Please
describe to this in method and discussion.
I raised a few questions to the authors. However, I think that the authors did very
good job. They handled subtle big SMTs which might need surgery. They
preserved the function of the stomach with successful enucleation of SMTs.
Furthermore, they exactly diagnosed the property of tumors.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests
Please review this paper.
user
Reviewer's report
Title:Modified endoscopic submucosal dissection with enucleation for treatment
of gastric subepithelial tumors originating from the muscularis propria layer
Version: 1Date:23 May 2012
Reviewer: Seok-Reyol Choi
Reviewer's report:
This paper described the Modified endoscopic submucosal dissection used for
enucleation of gastric subepithelial tumors originating from the muscularis propria
layer. This kind of concept is not noble, but this procedure is not yet widely
accepted. Thus, this paper has values to contribute the advent of endoscopic
procedure for exploring subepithelial tumors.
I would like to point out three major revisions.
1. Page 7 and Figures. I do not understand the modified ESD exactly. What is
the transverse incision exactly? Longitudinal incision and transverse incision
makes cross shape incision? The Figure 1d does not show cross-shape incision.
I think not a picture but a simple illustration will explain this procedure more
properly. Please insert an illustration that explains the modified ESD, especially
two incision lines.
2. According to result, authors removed three tumors at fundus. As all
endoscopists know, it is not easy to remove EGC and SMT at fundus. Please
describe more how to remove those three lesions in method or discussion.
3. One of the important issues in this kind of procedures is that we could not
evaluate the resection margin. Practitioners can enucleate the SMT, but they are
not able to check whether the resection margin is clear or not pathologically. In
this matter, I would like to listen to authors’ opinion. So called endoscopic
complete enucleation can guarantee pathologic complete resection? Please
describe to this in method and discussion.
I raised a few questions to the authors. However, I think that the authors did very
good job. They handled subtle big SMTs which might need surgery. They
preserved the function of the stomach with successful enucleation of SMTs.
Furthermore, they exactly diagnosed the property of tumors.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests
assistant