Title: Threshold of Main Pancreatic Duct for Malignancy in Intraductal Papillary  Mucinous
Neoplasm at Head-neck and Body-tail
Version: 1 Date: 01 Oct 2022
Reviewer's report:
Interesting paper on a surgical series of IPMN. I think the main limitation is the risk of selection
bias due to the fact that all patients underwent surgery. This way all the other patients are
excluded from the analysis thus missing other potential prognostic factors.
Other comments:
1) English grammar should be improved. I recommend the authors to have their manuscript
revised by a native speaker
2) I would emphasize in the discussion the role of EUS-through the needle biopsy in the
diagnostic management of PCLs, citing the recent relevant papers PMID: 35451041  and PMID:
32014422
3) I would also quickly comment the role of EUS in general in the management of pancreatic
lesions (both cystic and solid) citing the papers PMID: 35124072  and PMID: 27356212)
Title: Threshold of Main Pancreatic Duct for Malignancy in Intraductal Papillary  Mucinous
Neoplasm at Head-neck and Body-tail
Version: 1 Date: 01 Oct 2022
Reviewer's report:
Interesting paper on a surgical series of IPMN. I think the main limitation is the risk of selection
bias due to the fact that all patients underwent surgery. This way all the other patients are
excluded from the analysis thus missing other potential prognostic factors.
Other comments:
1) English grammar should be improved. I recommend the authors to have their manuscript
revised by a native speaker
2) I would emphasize in the discussion the role of EUS-through the needle biopsy in the
diagnostic management of PCLs, citing the recent relevant papers PMID: 35451041  and PMID:
32014422
3) I would also quickly comment the role of EUS in general in the management of pancreatic
lesions (both cystic and solid) citing the papers PMID: 35124072  and PMID: 27356212)
Please review this paper.
user
Title: Threshold of Main Pancreatic Duct for Malignancy in Intraductal Papillary  Mucinous
Neoplasm at Head-neck and Body-tail
Version: 1 Date: 01 Oct 2022
Reviewer's report:
Interesting paper on a surgical series of IPMN. I think the main limitation is the risk of selection
bias due to the fact that all patients underwent surgery. This way all the other patients are
excluded from the analysis thus missing other potential prognostic factors.
Other comments:
1) English grammar should be improved. I recommend the authors to have their manuscript
revised by a native speaker
2) I would emphasize in the discussion the role of EUS-through the needle biopsy in the
diagnostic management of PCLs, citing the recent relevant papers PMID: 35451041  and PMID:
32014422
3) I would also quickly comment the role of EUS in general in the management of pancreatic
lesions (both cystic and solid) citing the papers PMID: 35124072  and PMID: 27356212)
assistant