Reviewer's report
Title:Laparoscopic versus open appendectomy in patients with suspected
appendicitis: a systematic review of meta-analyses of randomised controlled
trials
Version:2Date:17 February 2015
Reviewer: Nereo Vettoretto
Reviewer's report:
Discretionary revisions: in discussion the authors cite different approaches to the
treatment of acute appendicitis and the references 21,22 are intended to
compare single incision laparoscopic appendectomy (LA) vs conventional three
port LA. this should be mentioned more specifically in the text and I would also
introduce the conservative antibiotic therapy as an alternative (cit. Di Saverio S,
Sibilio A, Giorgini E, Biscardi A, Villani S, Coccolini F, Smerieri N, Pisano M,
Ansaloni L, Sartelli M, Catena F, Tugnoli G. The NOTA Study (Non Operative
Treatment for Acute Appendicitis): prospective study on the efficacy and safety of
antibiotics (amoxicillin and clavulanic acid) for treating patients with right lower
quadrant abdominal pain and long-term follow-up of conservatively treated
suspected appendicitis. Ann Surg. 2014 Jul;260(1):109-17.).
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: Yes, but I do not feel adequately qualified to assess the
statistics.
Declaration of competing interests:
I declare that I have no competing interests
Reviewer's report
Title:Laparoscopic versus open appendectomy in patients with suspected
appendicitis: a systematic review of meta-analyses of randomised controlled
trials
Version:2Date:17 February 2015
Reviewer: Nereo Vettoretto
Reviewer's report:
Discretionary revisions: in discussion the authors cite different approaches to the
treatment of acute appendicitis and the references 21,22 are intended to
compare single incision laparoscopic appendectomy (LA) vs conventional three
port LA. this should be mentioned more specifically in the text and I would also
introduce the conservative antibiotic therapy as an alternative (cit. Di Saverio S,
Sibilio A, Giorgini E, Biscardi A, Villani S, Coccolini F, Smerieri N, Pisano M,
Ansaloni L, Sartelli M, Catena F, Tugnoli G. The NOTA Study (Non Operative
Treatment for Acute Appendicitis): prospective study on the efficacy and safety of
antibiotics (amoxicillin and clavulanic acid) for treating patients with right lower
quadrant abdominal pain and long-term follow-up of conservatively treated
suspected appendicitis. Ann Surg. 2014 Jul;260(1):109-17.).
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: Yes, but I do not feel adequately qualified to assess the
statistics.
Declaration of competing interests:
I declare that I have no competing interests
Please review this paper.
user
Reviewer's report
Title:Laparoscopic versus open appendectomy in patients with suspected
appendicitis: a systematic review of meta-analyses of randomised controlled
trials
Version:2Date:17 February 2015
Reviewer: Nereo Vettoretto
Reviewer's report:
Discretionary revisions: in discussion the authors cite different approaches to the
treatment of acute appendicitis and the references 21,22 are intended to
compare single incision laparoscopic appendectomy (LA) vs conventional three
port LA. this should be mentioned more specifically in the text and I would also
introduce the conservative antibiotic therapy as an alternative (cit. Di Saverio S,
Sibilio A, Giorgini E, Biscardi A, Villani S, Coccolini F, Smerieri N, Pisano M,
Ansaloni L, Sartelli M, Catena F, Tugnoli G. The NOTA Study (Non Operative
Treatment for Acute Appendicitis): prospective study on the efficacy and safety of
antibiotics (amoxicillin and clavulanic acid) for treating patients with right lower
quadrant abdominal pain and long-term follow-up of conservatively treated
suspected appendicitis. Ann Surg. 2014 Jul;260(1):109-17.).
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: Yes, but I do not feel adequately qualified to assess the
statistics.
Declaration of competing interests:
I declare that I have no competing interests
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