Reviewer's report
Title:Associations of a PTPN11 G/A polymorphism at intron 3 with Helicobactor
pylori seropositivity, gastric atrophy and gastric cancer in Japanese
Version: 1Date:29 October 2008
Reviewer: Haruhiko Sugimura
Reviewer's report:
major:
It is not clear to calculate OR for the subpopulation of severe gastric atrophy and
Hp infected severe gastric atrophy. Please state clearly what this subpopulation
represent?
minor
A seronegative, but sever gastric atrophic population were added in table 4b and
it generated the significant difference. What explains the seronegative gastric
atrophy? Is it the same pathway in seropositive atrophy?
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests. HS
Reviewer's report
Title:Associations of a PTPN11 G/A polymorphism at intron 3 with Helicobactor
pylori seropositivity, gastric atrophy and gastric cancer in Japanese
Version: 1Date:29 October 2008
Reviewer: Haruhiko Sugimura
Reviewer's report:
major:
It is not clear to calculate OR for the subpopulation of severe gastric atrophy and
Hp infected severe gastric atrophy. Please state clearly what this subpopulation
represent?
minor
A seronegative, but sever gastric atrophic population were added in table 4b and
it generated the significant difference. What explains the seronegative gastric
atrophy? Is it the same pathway in seropositive atrophy?
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests. HS
Please review this paper.
user
Reviewer's report
Title:Associations of a PTPN11 G/A polymorphism at intron 3 with Helicobactor
pylori seropositivity, gastric atrophy and gastric cancer in Japanese
Version: 1Date:29 October 2008
Reviewer: Haruhiko Sugimura
Reviewer's report:
major:
It is not clear to calculate OR for the subpopulation of severe gastric atrophy and
Hp infected severe gastric atrophy. Please state clearly what this subpopulation
represent?
minor
A seronegative, but sever gastric atrophic population were added in table 4b and
it generated the significant difference. What explains the seronegative gastric
atrophy? Is it the same pathway in seropositive atrophy?
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests. HS
assistant