Reviewer's report
Title:Laxative effects of Salecan on normal and two models of experimental
constipated mice
Version: 4Date:6 February 2013
Reviewer: fenghong huang
Reviewer's report:
Major Compulsory Revisions
1. The authors still don’t state whether the animals were fasted in fecal
parameters measurements in normal mice. Why were the animals given food
before the fecal parameters measurements in two types of constipation model
mice? Please provide the related references. If the animals were fasted in these
studies, how can the authors make sure that the feces collected within 8 h were
produced during the experimental period?
2. It is meaningless to state the effects of short chain fatty acids if the authors
can’t provide evidences that salecan can produce short chain fatty acids.
Level of interest: An article of limited interest
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests
Reviewer's report
Title:Laxative effects of Salecan on normal and two models of experimental
constipated mice
Version: 4Date:6 February 2013
Reviewer: fenghong huang
Reviewer's report:
Major Compulsory Revisions
1. The authors still don’t state whether the animals were fasted in fecal
parameters measurements in normal mice. Why were the animals given food
before the fecal parameters measurements in two types of constipation model
mice? Please provide the related references. If the animals were fasted in these
studies, how can the authors make sure that the feces collected within 8 h were
produced during the experimental period?
2. It is meaningless to state the effects of short chain fatty acids if the authors
can’t provide evidences that salecan can produce short chain fatty acids.
Level of interest: An article of limited interest
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests
Please review this paper.
user
Reviewer's report
Title:Laxative effects of Salecan on normal and two models of experimental
constipated mice
Version: 4Date:6 February 2013
Reviewer: fenghong huang
Reviewer's report:
Major Compulsory Revisions
1. The authors still don’t state whether the animals were fasted in fecal
parameters measurements in normal mice. Why were the animals given food
before the fecal parameters measurements in two types of constipation model
mice? Please provide the related references. If the animals were fasted in these
studies, how can the authors make sure that the feces collected within 8 h were
produced during the experimental period?
2. It is meaningless to state the effects of short chain fatty acids if the authors
can’t provide evidences that salecan can produce short chain fatty acids.
Level of interest: An article of limited interest
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests
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