Reviewer's report
Title:Prevalence of pre-transplant electrocardiographic abnormalities and
post-transplant cardiac events in patients with liver cirrhosis
Version:2Date:18 January 2014
Reviewer: Jorge Quiroga
Reviewer's report:
Minor essential revisions
1. Were the patients subjected to procedures after the pretransplant cardiac
work-up ?. For example, pacemaker placement, coronary artery ballooning or
stenting or cardiac resincronization?. If so, the basal EKG, that is the core of this
study is not the true pre-transplant EKG. This points needs clarification.
2. There were cardiac events during the transplant surgery?. If so, were these
events recorded and included as post-transplant cardiac complications in this
series?. Introperative time is period of special risk for these events and this ponit
needs clarification
3. The cases of post-transplant deaths due to heart disease should be detailed
and its relationship with pre-transplant EKG alterations explained. Numerical data
may be added to table 5.
4. This same group of investigators reported previously (reference 13 in this
paper) the occurrence of peri-transplant heart failure in virtually this same series
of patients (186 patients in this paper and 177 in the previous one). The previous
paper included detailed pre-transplant echocardiographic data and only few EKG
data. The decision of the author´s of spliting pre-transplant heart data in two
papers is acceptable but jeopardizes, at least in part, the global comprehension
of the impact of heart disease on post-transplant evolution. In this reviewer´s
oppinion the paper would be improved if the authors make an effort for
integrating in the discussion of this paper the information they obtained in the
previous one. Surprinsingly, the comments the authors devote to that paper in
the discussion are extremely scarce.
5. The number of patients that were finally evaluated should be mentioned in the
abstract
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
I declare that I have no competing interests
Reviewer's report
Title:Prevalence of pre-transplant electrocardiographic abnormalities and
post-transplant cardiac events in patients with liver cirrhosis
Version:2Date:18 January 2014
Reviewer: Jorge Quiroga
Reviewer's report:
Minor essential revisions
1. Were the patients subjected to procedures after the pretransplant cardiac
work-up ?. For example, pacemaker placement, coronary artery ballooning or
stenting or cardiac resincronization?. If so, the basal EKG, that is the core of this
study is not the true pre-transplant EKG. This points needs clarification.
2. There were cardiac events during the transplant surgery?. If so, were these
events recorded and included as post-transplant cardiac complications in this
series?. Introperative time is period of special risk for these events and this ponit
needs clarification
3. The cases of post-transplant deaths due to heart disease should be detailed
and its relationship with pre-transplant EKG alterations explained. Numerical data
may be added to table 5.
4. This same group of investigators reported previously (reference 13 in this
paper) the occurrence of peri-transplant heart failure in virtually this same series
of patients (186 patients in this paper and 177 in the previous one). The previous
paper included detailed pre-transplant echocardiographic data and only few EKG
data. The decision of the author´s of spliting pre-transplant heart data in two
papers is acceptable but jeopardizes, at least in part, the global comprehension
of the impact of heart disease on post-transplant evolution. In this reviewer´s
oppinion the paper would be improved if the authors make an effort for
integrating in the discussion of this paper the information they obtained in the
previous one. Surprinsingly, the comments the authors devote to that paper in
the discussion are extremely scarce.
5. The number of patients that were finally evaluated should be mentioned in the
abstract
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
I declare that I have no competing interests
Please review this paper.
user
Reviewer's report
Title:Prevalence of pre-transplant electrocardiographic abnormalities and
post-transplant cardiac events in patients with liver cirrhosis
Version:2Date:18 January 2014
Reviewer: Jorge Quiroga
Reviewer's report:
Minor essential revisions
1. Were the patients subjected to procedures after the pretransplant cardiac
work-up ?. For example, pacemaker placement, coronary artery ballooning or
stenting or cardiac resincronization?. If so, the basal EKG, that is the core of this
study is not the true pre-transplant EKG. This points needs clarification.
2. There were cardiac events during the transplant surgery?. If so, were these
events recorded and included as post-transplant cardiac complications in this
series?. Introperative time is period of special risk for these events and this ponit
needs clarification
3. The cases of post-transplant deaths due to heart disease should be detailed
and its relationship with pre-transplant EKG alterations explained. Numerical data
may be added to table 5.
4. This same group of investigators reported previously (reference 13 in this
paper) the occurrence of peri-transplant heart failure in virtually this same series
of patients (186 patients in this paper and 177 in the previous one). The previous
paper included detailed pre-transplant echocardiographic data and only few EKG
data. The decision of the author´s of spliting pre-transplant heart data in two
papers is acceptable but jeopardizes, at least in part, the global comprehension
of the impact of heart disease on post-transplant evolution. In this reviewer´s
oppinion the paper would be improved if the authors make an effort for
integrating in the discussion of this paper the information they obtained in the
previous one. Surprinsingly, the comments the authors devote to that paper in
the discussion are extremely scarce.
5. The number of patients that were finally evaluated should be mentioned in the
abstract
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
I declare that I have no competing interests
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