Reviewer's report 
 Dapsone induced cholangitis as a part of dapsone syndrome: a case report Title: 
Authors: 
Srivenu Itha ( srivenu@sgpgi.ac.in )
Dr Ashish Kumar ( ashishk@sgpgi.ac.in )
Sadhna Dhingra ( sdhingra@sgpgi.ac.in )
Gourdas Choudhuri ( gourdas@satyam.net.in )
 1  2 Apr 2003 Version: Date: 
 Regina Helena Costa H Queiroz Reviewer: 
 not specified Level of interest: 
 Accept after discretionary revisions Advice on publication: 
1.The manuscript contains original work , which may contribute significantly to BMC 
Gastroenterology. 2.New references must be included in the Background( especially about dapsone and agranulocytosis, a very important hypersensitivity reaction).In the discussion, what the author think 
about the relationship of the hepatic metabolism of dapsone and the cholangitis ? (Michael D. 
Coleman, reported reviews about mechanisms of dapsone toxicity) 3. I recommend a revision of the discussion of this manuscript. 
Competing interests: 
None declared. 
Reviewer's report 
 Dapsone induced cholangitis as a part of dapsone syndrome: a case report Title: 
Authors: 
Srivenu Itha ( srivenu@sgpgi.ac.in )
Dr Ashish Kumar ( ashishk@sgpgi.ac.in )
Sadhna Dhingra ( sdhingra@sgpgi.ac.in )
Gourdas Choudhuri ( gourdas@satyam.net.in )
 1  2 Apr 2003 Version: Date: 
 Regina Helena Costa H Queiroz Reviewer: 
 not specified Level of interest: 
 Accept after discretionary revisions Advice on publication: 
1.The manuscript contains original work , which may contribute significantly to BMC 
Gastroenterology. 2.New references must be included in the Background( especially about dapsone and agranulocytosis, a very important hypersensitivity reaction).In the discussion, what the author think 
about the relationship of the hepatic metabolism of dapsone and the cholangitis ? (Michael D. 
Coleman, reported reviews about mechanisms of dapsone toxicity) 3. I recommend a revision of the discussion of this manuscript. 
Competing interests: 
None declared. 
Please review this paper.
user
Reviewer's report 
 Dapsone induced cholangitis as a part of dapsone syndrome: a case report Title: 
Authors: 
Srivenu Itha ( srivenu@sgpgi.ac.in )
Dr Ashish Kumar ( ashishk@sgpgi.ac.in )
Sadhna Dhingra ( sdhingra@sgpgi.ac.in )
Gourdas Choudhuri ( gourdas@satyam.net.in )
 1  2 Apr 2003 Version: Date: 
 Regina Helena Costa H Queiroz Reviewer: 
 not specified Level of interest: 
 Accept after discretionary revisions Advice on publication: 
1.The manuscript contains original work , which may contribute significantly to BMC 
Gastroenterology. 2.New references must be included in the Background( especially about dapsone and agranulocytosis, a very important hypersensitivity reaction).In the discussion, what the author think 
about the relationship of the hepatic metabolism of dapsone and the cholangitis ? (Michael D. 
Coleman, reported reviews about mechanisms of dapsone toxicity) 3. I recommend a revision of the discussion of this manuscript. 
Competing interests: 
None declared. 
assistant