Title: Analysis of the Correlation between Defunctioning Stoma and Postoperative Low
Anterior Resection Syndrome in Rectal Cancer#A prospective cohort study
Version: 4 Date: 07 Aug 2024
Reviewer's report:
Author Yuhan et al. have generally addressed the reviewers' comments, but I would like to make
two following comments, including one minor revision. Even taking that into account, this paper
is valuable in that it is a prospective cohort with large number of cases, and although the results
are not remarkable for their novelty, they are informative for the reader.
Comment1:
The authors have removed 'previous surgery' from the exclusion criteria, but it is inappropriate
for a study to change the indication/exclusion criteria later in a prospective cohort. Please
consider the study design in detail in advance and make sure that indications and exclusions are
well judged before statistical analysis for future studies.
Comment2(minor revision):
Table 1 has not been properly corrected. The reviewer repeatedly stated that the English version
of Emmertsen's LARS score should be included in Table 1. The content of Table 1 in this paper
is the authors' original English wording, which differs from Emmertsen's English version of the
LARS score, which was the original Chinese version of the LARS score. The following is the
English version of Emmertsen's LARS score, so please use this for Table 1 in the text.
Do you ever have occasions when you cannot control your flatus (wind)?
#No, never
#Yes, less than once per week
#Yes, at least once per week
Do you ever have any accidental leakage of liquid stool?
#No, never
#Yes, less than once per week
#Yes, at least once per week
How often do you open your bowels?
#More than 7 times per day (24 hours)
#4–7 times per day (24 hours)
#1–3 times per day (24 hours)
#Less than once per day (24 hours)
Do you ever have to open your bowels again within one hour of the last bowel opening?
#No, never
#Yes, less than once per week
#Yes, at least once per week
Do you ever have such a strong urge to open your bowels that you have to rush to the toilet?
#No, never
#Yes, less than once per week
#Yes, at least once per week
Title: Analysis of the Correlation between Defunctioning Stoma and Postoperative Low
Anterior Resection Syndrome in Rectal Cancer#A prospective cohort study
Version: 4 Date: 07 Aug 2024
Reviewer's report:
Author Yuhan et al. have generally addressed the reviewers' comments, but I would like to make
two following comments, including one minor revision. Even taking that into account, this paper
is valuable in that it is a prospective cohort with large number of cases, and although the results
are not remarkable for their novelty, they are informative for the reader.
Comment1:
The authors have removed 'previous surgery' from the exclusion criteria, but it is inappropriate
for a study to change the indication/exclusion criteria later in a prospective cohort. Please
consider the study design in detail in advance and make sure that indications and exclusions are
well judged before statistical analysis for future studies.
Comment2(minor revision):
Table 1 has not been properly corrected. The reviewer repeatedly stated that the English version
of Emmertsen's LARS score should be included in Table 1. The content of Table 1 in this paper
is the authors' original English wording, which differs from Emmertsen's English version of the
LARS score, which was the original Chinese version of the LARS score. The following is the
English version of Emmertsen's LARS score, so please use this for Table 1 in the text.
Do you ever have occasions when you cannot control your flatus (wind)?
#No, never
#Yes, less than once per week
#Yes, at least once per week
Do you ever have any accidental leakage of liquid stool?
#No, never
#Yes, less than once per week
#Yes, at least once per week
How often do you open your bowels?
#More than 7 times per day (24 hours)
#4–7 times per day (24 hours)
#1–3 times per day (24 hours)
#Less than once per day (24 hours)
Do you ever have to open your bowels again within one hour of the last bowel opening?
#No, never
#Yes, less than once per week
#Yes, at least once per week
Do you ever have such a strong urge to open your bowels that you have to rush to the toilet?
#No, never
#Yes, less than once per week
#Yes, at least once per week
Please review this paper.
user
Title: Analysis of the Correlation between Defunctioning Stoma and Postoperative Low
Anterior Resection Syndrome in Rectal Cancer#A prospective cohort study
Version: 4 Date: 07 Aug 2024
Reviewer's report:
Author Yuhan et al. have generally addressed the reviewers' comments, but I would like to make
two following comments, including one minor revision. Even taking that into account, this paper
is valuable in that it is a prospective cohort with large number of cases, and although the results
are not remarkable for their novelty, they are informative for the reader.
Comment1:
The authors have removed 'previous surgery' from the exclusion criteria, but it is inappropriate
for a study to change the indication/exclusion criteria later in a prospective cohort. Please
consider the study design in detail in advance and make sure that indications and exclusions are
well judged before statistical analysis for future studies.
Comment2(minor revision):
Table 1 has not been properly corrected. The reviewer repeatedly stated that the English version
of Emmertsen's LARS score should be included in Table 1. The content of Table 1 in this paper
is the authors' original English wording, which differs from Emmertsen's English version of the
LARS score, which was the original Chinese version of the LARS score. The following is the
English version of Emmertsen's LARS score, so please use this for Table 1 in the text.
Do you ever have occasions when you cannot control your flatus (wind)?
#No, never
#Yes, less than once per week
#Yes, at least once per week
Do you ever have any accidental leakage of liquid stool?
#No, never
#Yes, less than once per week
#Yes, at least once per week
How often do you open your bowels?
#More than 7 times per day (24 hours)
#4–7 times per day (24 hours)
#1–3 times per day (24 hours)
#Less than once per day (24 hours)
Do you ever have to open your bowels again within one hour of the last bowel opening?
#No, never
#Yes, less than once per week
#Yes, at least once per week
Do you ever have such a strong urge to open your bowels that you have to rush to the toilet?
#No, never
#Yes, less than once per week
#Yes, at least once per week
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