Title: Association between the triglyceride glucose index and the risk of acute respiratory failure
in patients with acute pancreatitis
Version: 1 Date: 13 Feb 2025
Reviewer's report:
Thank you for this revision, which improved the quality of your paper!
I still have minor remarks :
- I think you should move the paragraph "Pancreatitis can lead to decreased pancreatic insulin
secretion and increased peripheral IR. Studies had shown that chronic h..., this mechanism could
also contribute to the onset of ARF [22]" from the discussion to the introduction section, in order
to explain why you want to perform your study earlier in your paper.
- I am still not completely convinced about the superiority of Tyg as compared to just checking
if people have hyperglycemia linked to a stress state associated with their severe AP. Maybe
you could just try to compare the ROC of Tyg for ARF prediction vs the ROC of blood glucose
alone or the ROC of TG alone? If the AUC of these isolated variables is lower than the one with
Tyg, you will have a strong argument to say that it is a more interesting marker.
Title: Association between the triglyceride glucose index and the risk of acute respiratory failure
in patients with acute pancreatitis
Version: 1 Date: 13 Feb 2025
Reviewer's report:
Thank you for this revision, which improved the quality of your paper!
I still have minor remarks :
- I think you should move the paragraph "Pancreatitis can lead to decreased pancreatic insulin
secretion and increased peripheral IR. Studies had shown that chronic h..., this mechanism could
also contribute to the onset of ARF [22]" from the discussion to the introduction section, in order
to explain why you want to perform your study earlier in your paper.
- I am still not completely convinced about the superiority of Tyg as compared to just checking
if people have hyperglycemia linked to a stress state associated with their severe AP. Maybe
you could just try to compare the ROC of Tyg for ARF prediction vs the ROC of blood glucose
alone or the ROC of TG alone? If the AUC of these isolated variables is lower than the one with
Tyg, you will have a strong argument to say that it is a more interesting marker.
Please review this paper.
user
Title: Association between the triglyceride glucose index and the risk of acute respiratory failure
in patients with acute pancreatitis
Version: 1 Date: 13 Feb 2025
Reviewer's report:
Thank you for this revision, which improved the quality of your paper!
I still have minor remarks :
- I think you should move the paragraph "Pancreatitis can lead to decreased pancreatic insulin
secretion and increased peripheral IR. Studies had shown that chronic h..., this mechanism could
also contribute to the onset of ARF [22]" from the discussion to the introduction section, in order
to explain why you want to perform your study earlier in your paper.
- I am still not completely convinced about the superiority of Tyg as compared to just checking
if people have hyperglycemia linked to a stress state associated with their severe AP. Maybe
you could just try to compare the ROC of Tyg for ARF prediction vs the ROC of blood glucose
alone or the ROC of TG alone? If the AUC of these isolated variables is lower than the one with
Tyg, you will have a strong argument to say that it is a more interesting marker.
assistant