Title: Evaluation of symptomatic small bowel stricture in Crohn’s disease by double-balloon
endoscopy
Version: 1 Date: 19 Feb 2023
Reviewer's report:
I read the paper titled 'Evaluation of symptomatic small bowel stricture in Crohn’s disease by
double-balloon endoscopy' interestingly and appreciate the authors for their academic efforts
to figure out the role of DBE in stricturing small bowel CD. Here are my comments regarding
this study.
Major comments.
1. The authors showed that DBE found more small bowel strictures than CT enterography (CTE),
especially in those with low CDOS. I wonder which kinds of management were given to those
who had DBE-positive strictures with low CDOS. DBE is more sensitive to detecting small
intestinal strictures than CTE. However, if DBE-positive, mild strictures did not require any
change in management, the clinical role of DBE would be less significant.
2. If the authors performed therapeutic interventions for strictures, such as balloon dilation,
stricturoplasty, or bowel resection surgery, please provide the outcomes.
3. If available, please provide the clinical course of those with strictures detected by only DbE
and by only CTE, respectively.
Minor comments.
1. The introduction is a little excessively redundant and is felt somewhat incoherent in the
viewpoint of the study aims. I think the authors can brief the introduction focusing on their study
aims.
2. I recommend the authors get an English editing service to improve the readability for average
readers.
3. I found several typos or inadequately used upper cases in the manuscript, and they can be
corrected if an expert editing service is used.
4. Please provide abbreviations of repeated phrases or terms once when those appear first in
the manuscript.
Title: Evaluation of symptomatic small bowel stricture in Crohn’s disease by double-balloon
endoscopy
Version: 1 Date: 19 Feb 2023
Reviewer's report:
I read the paper titled 'Evaluation of symptomatic small bowel stricture in Crohn’s disease by
double-balloon endoscopy' interestingly and appreciate the authors for their academic efforts
to figure out the role of DBE in stricturing small bowel CD. Here are my comments regarding
this study.
Major comments.
1. The authors showed that DBE found more small bowel strictures than CT enterography (CTE),
especially in those with low CDOS. I wonder which kinds of management were given to those
who had DBE-positive strictures with low CDOS. DBE is more sensitive to detecting small
intestinal strictures than CTE. However, if DBE-positive, mild strictures did not require any
change in management, the clinical role of DBE would be less significant.
2. If the authors performed therapeutic interventions for strictures, such as balloon dilation,
stricturoplasty, or bowel resection surgery, please provide the outcomes.
3. If available, please provide the clinical course of those with strictures detected by only DbE
and by only CTE, respectively.
Minor comments.
1. The introduction is a little excessively redundant and is felt somewhat incoherent in the
viewpoint of the study aims. I think the authors can brief the introduction focusing on their study
aims.
2. I recommend the authors get an English editing service to improve the readability for average
readers.
3. I found several typos or inadequately used upper cases in the manuscript, and they can be
corrected if an expert editing service is used.
4. Please provide abbreviations of repeated phrases or terms once when those appear first in
the manuscript.
Please review this paper.
user
Title: Evaluation of symptomatic small bowel stricture in Crohn’s disease by double-balloon
endoscopy
Version: 1 Date: 19 Feb 2023
Reviewer's report:
I read the paper titled 'Evaluation of symptomatic small bowel stricture in Crohn’s disease by
double-balloon endoscopy' interestingly and appreciate the authors for their academic efforts
to figure out the role of DBE in stricturing small bowel CD. Here are my comments regarding
this study.
Major comments.
1. The authors showed that DBE found more small bowel strictures than CT enterography (CTE),
especially in those with low CDOS. I wonder which kinds of management were given to those
who had DBE-positive strictures with low CDOS. DBE is more sensitive to detecting small
intestinal strictures than CTE. However, if DBE-positive, mild strictures did not require any
change in management, the clinical role of DBE would be less significant.
2. If the authors performed therapeutic interventions for strictures, such as balloon dilation,
stricturoplasty, or bowel resection surgery, please provide the outcomes.
3. If available, please provide the clinical course of those with strictures detected by only DbE
and by only CTE, respectively.
Minor comments.
1. The introduction is a little excessively redundant and is felt somewhat incoherent in the
viewpoint of the study aims. I think the authors can brief the introduction focusing on their study
aims.
2. I recommend the authors get an English editing service to improve the readability for average
readers.
3. I found several typos or inadequately used upper cases in the manuscript, and they can be
corrected if an expert editing service is used.
4. Please provide abbreviations of repeated phrases or terms once when those appear first in
the manuscript.
assistant