Title: A Comprehensive Analysis of Percutaneous Liver Biopsy Characteristics and
Pathological Manifestations in a Large Patient Cohort (2009-2024)
Version: 3 Date: 09 Dec 2024
Reviewer's report:
This retrospective study done to analyze the characteristics of patients undergoing percutaneous
liver biopsies and investigate the pathological manifestations of four principal liver diseases
across different age groups: chronic hepatitis B, chronic hepatitis B complicated by metabolic
dysfunction-associated steatotic liver disease (MASLD), liver function abnormalities, and
standalone MASLD. its not clear from the study  whether the liver biopsies were done as a part
of the study protocol or  they were done only when  diagnosis was not clear , otherwise  fibroscan
of the liver / liver elastography  are non invasive procedures which are carried out for the above
mentioned diseases  to assess degree of fibrosis and monitor progression to fibrosis
Title: A Comprehensive Analysis of Percutaneous Liver Biopsy Characteristics and
Pathological Manifestations in a Large Patient Cohort (2009-2024)
Version: 3 Date: 09 Dec 2024
Reviewer's report:
This retrospective study done to analyze the characteristics of patients undergoing percutaneous
liver biopsies and investigate the pathological manifestations of four principal liver diseases
across different age groups: chronic hepatitis B, chronic hepatitis B complicated by metabolic
dysfunction-associated steatotic liver disease (MASLD), liver function abnormalities, and
standalone MASLD. its not clear from the study  whether the liver biopsies were done as a part
of the study protocol or  they were done only when  diagnosis was not clear , otherwise  fibroscan
of the liver / liver elastography  are non invasive procedures which are carried out for the above
mentioned diseases  to assess degree of fibrosis and monitor progression to fibrosis
Please review this paper.
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Title: A Comprehensive Analysis of Percutaneous Liver Biopsy Characteristics and
Pathological Manifestations in a Large Patient Cohort (2009-2024)
Version: 3 Date: 09 Dec 2024
Reviewer's report:
This retrospective study done to analyze the characteristics of patients undergoing percutaneous
liver biopsies and investigate the pathological manifestations of four principal liver diseases
across different age groups: chronic hepatitis B, chronic hepatitis B complicated by metabolic
dysfunction-associated steatotic liver disease (MASLD), liver function abnormalities, and
standalone MASLD. its not clear from the study  whether the liver biopsies were done as a part
of the study protocol or  they were done only when  diagnosis was not clear , otherwise  fibroscan
of the liver / liver elastography  are non invasive procedures which are carried out for the above
mentioned diseases  to assess degree of fibrosis and monitor progression to fibrosis
assistant