Title: Title: Clinicopathologic characteristics and prognosis of synchronous colorectal cancer:
A retrospective study
Version: 0 Date: 03 Dec 2021
Reviewer's report:
although this study concerns a large cohort, 26% of patients are not studied because they are
considered lost to follow-up, well above the less than 10% admitted to validate conclusions.
this loss of follow-up rate is a major limit.
this point should at least be mentioned in the discussion
the percentage of 27% of SCRC is much higher than that of the literature, and should also be
at least mentioned in the discussion.
the authors studied the operated CRCs in their structure, the conclusions can therefore only
concern the operated patients and not all the CRCs.
this study presents multiple results making reading difficult and would undoubtedly deserve to
be divided into 2 papers: 1 comparing the PCRC and the SCRC, and a 2nd comparing the EO
CRC and the LO CRC.
several factors studied, such as CA125, CA153, alphafoetoprotein, KI expression and ascites,
are of no interest and could be deleted from the article to facilitate understanding.
Title: Title: Clinicopathologic characteristics and prognosis of synchronous colorectal cancer:
A retrospective study
Version: 0 Date: 03 Dec 2021
Reviewer's report:
although this study concerns a large cohort, 26% of patients are not studied because they are
considered lost to follow-up, well above the less than 10% admitted to validate conclusions.
this loss of follow-up rate is a major limit.
this point should at least be mentioned in the discussion
the percentage of 27% of SCRC is much higher than that of the literature, and should also be
at least mentioned in the discussion.
the authors studied the operated CRCs in their structure, the conclusions can therefore only
concern the operated patients and not all the CRCs.
this study presents multiple results making reading difficult and would undoubtedly deserve to
be divided into 2 papers: 1 comparing the PCRC and the SCRC, and a 2nd comparing the EO
CRC and the LO CRC.
several factors studied, such as CA125, CA153, alphafoetoprotein, KI expression and ascites,
are of no interest and could be deleted from the article to facilitate understanding.
Please review this paper.
user
Title: Title: Clinicopathologic characteristics and prognosis of synchronous colorectal cancer:
A retrospective study
Version: 0 Date: 03 Dec 2021
Reviewer's report:
although this study concerns a large cohort, 26% of patients are not studied because they are
considered lost to follow-up, well above the less than 10% admitted to validate conclusions.
this loss of follow-up rate is a major limit.
this point should at least be mentioned in the discussion
the percentage of 27% of SCRC is much higher than that of the literature, and should also be
at least mentioned in the discussion.
the authors studied the operated CRCs in their structure, the conclusions can therefore only
concern the operated patients and not all the CRCs.
this study presents multiple results making reading difficult and would undoubtedly deserve to
be divided into 2 papers: 1 comparing the PCRC and the SCRC, and a 2nd comparing the EO
CRC and the LO CRC.
several factors studied, such as CA125, CA153, alphafoetoprotein, KI expression and ascites,
are of no interest and could be deleted from the article to facilitate understanding.
assistant