Title: Routine Psychological problems Screening in Hospitalized Inflammatory Bowel Diseases
and Its Effect for Progression-free Survival from Disease Worsening
Version: 1 Date: 15 Mar 2025
Reviewer:  Yoriaki Komeda
Reviewer's report:
This manuscript is a retrospective study evaluating the impact of psychological screening at
the time of hospitalization on disease worsening and long-term outcomes in patients with
inflammatory bowel disease (IBD). The study design is clear, and appropriate statistical methods
are used. However, several areas require improvement.
The study is described as a "case-control study," but it may be more appropriate to classify it
as a retrospective cohort study.
Regarding statistical analysis, the details of the propensity score matching (PSM), including the
variables used and the specific matching method, should be described in more detail to enhance
reproducibility for readers.
It is stated that "the screening group had a longer hospital stay, leading to a higher incidence of
adverse events (venous thromboembolism and pneumonia)." Could this be due to the severity
of the underlying disease? Please provide additional clarification.
The study uses PHQ-8 and GAD-7 as screening tools. It would be helpful to include the
questionnaire sheets as a supplementary figure or appendix for better understanding.
Title: Routine Psychological problems Screening in Hospitalized Inflammatory Bowel Diseases
and Its Effect for Progression-free Survival from Disease Worsening
Version: 1 Date: 15 Mar 2025
Reviewer:  Yoriaki Komeda
Reviewer's report:
This manuscript is a retrospective study evaluating the impact of psychological screening at
the time of hospitalization on disease worsening and long-term outcomes in patients with
inflammatory bowel disease (IBD). The study design is clear, and appropriate statistical methods
are used. However, several areas require improvement.
The study is described as a "case-control study," but it may be more appropriate to classify it
as a retrospective cohort study.
Regarding statistical analysis, the details of the propensity score matching (PSM), including the
variables used and the specific matching method, should be described in more detail to enhance
reproducibility for readers.
It is stated that "the screening group had a longer hospital stay, leading to a higher incidence of
adverse events (venous thromboembolism and pneumonia)." Could this be due to the severity
of the underlying disease? Please provide additional clarification.
The study uses PHQ-8 and GAD-7 as screening tools. It would be helpful to include the
questionnaire sheets as a supplementary figure or appendix for better understanding.
Please review this paper.
user
Title: Routine Psychological problems Screening in Hospitalized Inflammatory Bowel Diseases
and Its Effect for Progression-free Survival from Disease Worsening
Version: 1 Date: 15 Mar 2025
Reviewer:  Yoriaki Komeda
Reviewer's report:
This manuscript is a retrospective study evaluating the impact of psychological screening at
the time of hospitalization on disease worsening and long-term outcomes in patients with
inflammatory bowel disease (IBD). The study design is clear, and appropriate statistical methods
are used. However, several areas require improvement.
The study is described as a "case-control study," but it may be more appropriate to classify it
as a retrospective cohort study.
Regarding statistical analysis, the details of the propensity score matching (PSM), including the
variables used and the specific matching method, should be described in more detail to enhance
reproducibility for readers.
It is stated that "the screening group had a longer hospital stay, leading to a higher incidence of
adverse events (venous thromboembolism and pneumonia)." Could this be due to the severity
of the underlying disease? Please provide additional clarification.
The study uses PHQ-8 and GAD-7 as screening tools. It would be helpful to include the
questionnaire sheets as a supplementary figure or appendix for better understanding.
assistant