Title: The insoluble excretion of multi-matrix system mesalazine preparations in patients with
ulcerative colitis
Version: 3 Date: 28 May 2022
Reviewer:  Sakuma Takahashi
Reviewer's report:
It is my pleasure to review the manuscript entitled "The insoluble excretion of multi-matrix
system mesalazine preparations in patients with ulcerative colitis".
However, I have several concerns that need to be addressed before considering publication.
1) Please read the submission guidelines of BMC Gastroenterology carefully.
For example, the title page should list the full names and institutional addresses for all authors
 and  indicate the corresponding author. Please unify the reference style.
2)  The authors use "P" and "p" to notate "P-value".
Please use the same terminology throughout the document.
3)  The authors use "N" and "n" to notate "number".
Please use the same terminology throughout the document.
4)  I’d recommend that the authors enlarge Figure 1.a (Insoluble MMX tablets in the rectum)
and add arrows to tablets.
5)  The authors write "Bristol Stool Form Scale score at the start of treatment  44 : 32 : 26" in
Table 1. Please specify which scale corresponds to those numbers.
Title: The insoluble excretion of multi-matrix system mesalazine preparations in patients with
ulcerative colitis
Version: 3 Date: 28 May 2022
Reviewer:  Sakuma Takahashi
Reviewer's report:
It is my pleasure to review the manuscript entitled "The insoluble excretion of multi-matrix
system mesalazine preparations in patients with ulcerative colitis".
However, I have several concerns that need to be addressed before considering publication.
1) Please read the submission guidelines of BMC Gastroenterology carefully.
For example, the title page should list the full names and institutional addresses for all authors
 and  indicate the corresponding author. Please unify the reference style.
2)  The authors use "P" and "p" to notate "P-value".
Please use the same terminology throughout the document.
3)  The authors use "N" and "n" to notate "number".
Please use the same terminology throughout the document.
4)  I’d recommend that the authors enlarge Figure 1.a (Insoluble MMX tablets in the rectum)
and add arrows to tablets.
5)  The authors write "Bristol Stool Form Scale score at the start of treatment  44 : 32 : 26" in
Table 1. Please specify which scale corresponds to those numbers.
Please review this paper.
user
Title: The insoluble excretion of multi-matrix system mesalazine preparations in patients with
ulcerative colitis
Version: 3 Date: 28 May 2022
Reviewer:  Sakuma Takahashi
Reviewer's report:
It is my pleasure to review the manuscript entitled "The insoluble excretion of multi-matrix
system mesalazine preparations in patients with ulcerative colitis".
However, I have several concerns that need to be addressed before considering publication.
1) Please read the submission guidelines of BMC Gastroenterology carefully.
For example, the title page should list the full names and institutional addresses for all authors
 and  indicate the corresponding author. Please unify the reference style.
2)  The authors use "P" and "p" to notate "P-value".
Please use the same terminology throughout the document.
3)  The authors use "N" and "n" to notate "number".
Please use the same terminology throughout the document.
4)  I’d recommend that the authors enlarge Figure 1.a (Insoluble MMX tablets in the rectum)
and add arrows to tablets.
5)  The authors write "Bristol Stool Form Scale score at the start of treatment  44 : 32 : 26" in
Table 1. Please specify which scale corresponds to those numbers.
assistant