Title: Indocyanine green fluorescence imaging localization-assisted thoracoscopy revision
surgery after repair of esophageal atresia
Version: 2 Date: 07 Jun 2022
Reviewer:  Stefaan H. A. J. Tytgat
Reviewer's report:
In this publication, the authors describe how they were able to clearly visualize recurrent trachea-
esophageal fistulae (rTEF) after esophageal atresia (EA) repair. Prior to the thoracoscopic rTEF
correction an indocyanine green (ICG) solution is sprayed in the fistula under bronchoscopic
guidance. With subsequent fluorescence imaging during the thoracoscopic dissection, the rTEF
can be identified and extensive dissection can be avoided.
Surgery for rTEF can be cumbersome, due to strong adhesions and local scar tissue formation.
Also identifying the rTEF and finding the plane between the trachea and the proximal esophagus
can be challenging, even for experienced surgeons. I believe that the suggested ICG fluorescence
rTEF identification could really be of help.
Stefaan Tytgat
University Medical Center Utrecht
The Netherlands
Title: Indocyanine green fluorescence imaging localization-assisted thoracoscopy revision
surgery after repair of esophageal atresia
Version: 2 Date: 07 Jun 2022
Reviewer:  Stefaan H. A. J. Tytgat
Reviewer's report:
In this publication, the authors describe how they were able to clearly visualize recurrent trachea-
esophageal fistulae (rTEF) after esophageal atresia (EA) repair. Prior to the thoracoscopic rTEF
correction an indocyanine green (ICG) solution is sprayed in the fistula under bronchoscopic
guidance. With subsequent fluorescence imaging during the thoracoscopic dissection, the rTEF
can be identified and extensive dissection can be avoided.
Surgery for rTEF can be cumbersome, due to strong adhesions and local scar tissue formation.
Also identifying the rTEF and finding the plane between the trachea and the proximal esophagus
can be challenging, even for experienced surgeons. I believe that the suggested ICG fluorescence
rTEF identification could really be of help.
Stefaan Tytgat
University Medical Center Utrecht
The Netherlands
Please review this paper.
user
Title: Indocyanine green fluorescence imaging localization-assisted thoracoscopy revision
surgery after repair of esophageal atresia
Version: 2 Date: 07 Jun 2022
Reviewer:  Stefaan H. A. J. Tytgat
Reviewer's report:
In this publication, the authors describe how they were able to clearly visualize recurrent trachea-
esophageal fistulae (rTEF) after esophageal atresia (EA) repair. Prior to the thoracoscopic rTEF
correction an indocyanine green (ICG) solution is sprayed in the fistula under bronchoscopic
guidance. With subsequent fluorescence imaging during the thoracoscopic dissection, the rTEF
can be identified and extensive dissection can be avoided.
Surgery for rTEF can be cumbersome, due to strong adhesions and local scar tissue formation.
Also identifying the rTEF and finding the plane between the trachea and the proximal esophagus
can be challenging, even for experienced surgeons. I believe that the suggested ICG fluorescence
rTEF identification could really be of help.
Stefaan Tytgat
University Medical Center Utrecht
The Netherlands
assistant