Title: Comorbid Psychiatric Disorders and Long-Term Survival after Liver Transplantation in
Transplant Facilities with a Psychiatric Consultation-Liaison Team: a Multicenter Retrospective
Study
Version: 6 Date: 09 Mar 2023
Reviewer's report:
This is a retrospective, non-randomized, observational study report with the title “Comorbid
Psychiatric Disorders and Long-Term Survival after Liver Transplantation in Transplant
Facilities with a Psychiatric Consultation-Liaison Team: a Multicenter Retrospective Study”.
The authors had made many revisions to the manuscript according to the reviewer’s suggestion
and the reviewer could accept the revisions made for the third review. The authors should
consider the impact for liver transplantation care in psychiatry. The reviewer has the following
question about this manuscript:
1. The reviewer appreciates the changes made for a clearer conclusion. However, it should be
made more apparent that the lack of impact of delirium and major depressive disorder on survival
after further Cox proportional hazards regression analysis is dependent on the fact that delirium
within the first week was excluded. Furthermore, previous studies have shown that delirium and
mortality are correlated, which contradicts the conclusion of this manuscript. Further discussion
regarding this point should be made.
Title: Comorbid Psychiatric Disorders and Long-Term Survival after Liver Transplantation in
Transplant Facilities with a Psychiatric Consultation-Liaison Team: a Multicenter Retrospective
Study
Version: 6 Date: 09 Mar 2023
Reviewer's report:
This is a retrospective, non-randomized, observational study report with the title “Comorbid
Psychiatric Disorders and Long-Term Survival after Liver Transplantation in Transplant
Facilities with a Psychiatric Consultation-Liaison Team: a Multicenter Retrospective Study”.
The authors had made many revisions to the manuscript according to the reviewer’s suggestion
and the reviewer could accept the revisions made for the third review. The authors should
consider the impact for liver transplantation care in psychiatry. The reviewer has the following
question about this manuscript:
1. The reviewer appreciates the changes made for a clearer conclusion. However, it should be
made more apparent that the lack of impact of delirium and major depressive disorder on survival
after further Cox proportional hazards regression analysis is dependent on the fact that delirium
within the first week was excluded. Furthermore, previous studies have shown that delirium and
mortality are correlated, which contradicts the conclusion of this manuscript. Further discussion
regarding this point should be made.
Please review this paper.
user
Title: Comorbid Psychiatric Disorders and Long-Term Survival after Liver Transplantation in
Transplant Facilities with a Psychiatric Consultation-Liaison Team: a Multicenter Retrospective
Study
Version: 6 Date: 09 Mar 2023
Reviewer's report:
This is a retrospective, non-randomized, observational study report with the title “Comorbid
Psychiatric Disorders and Long-Term Survival after Liver Transplantation in Transplant
Facilities with a Psychiatric Consultation-Liaison Team: a Multicenter Retrospective Study”.
The authors had made many revisions to the manuscript according to the reviewer’s suggestion
and the reviewer could accept the revisions made for the third review. The authors should
consider the impact for liver transplantation care in psychiatry. The reviewer has the following
question about this manuscript:
1. The reviewer appreciates the changes made for a clearer conclusion. However, it should be
made more apparent that the lack of impact of delirium and major depressive disorder on survival
after further Cox proportional hazards regression analysis is dependent on the fact that delirium
within the first week was excluded. Furthermore, previous studies have shown that delirium and
mortality are correlated, which contradicts the conclusion of this manuscript. Further discussion
regarding this point should be made.
assistant