Title: Endo-loop or Interrupted Suture Closure of Gallbladder Remnant During Laparoscopic
Subtotal Cholecystectomy- a Retrospective Analysis of Our Experience at a High-Volume
Centre of Eastern Nepal
Version: 4 Date: 13 Mar 2025
Reviewer's report:
1. The basis for comparison of both closure techniques may be faulty if the interrupted closure is
utilized when the posterior wall of the gallbladder is not adequately mobilizable enough to enable
application of an endoloop.  It could be argued that bile leak in the cases that had interrupted
suture closure was due to the difficulty in those cases.
2. It would also be important to compare the skill level of surgeons in both groups to see if that
influenced the outcomes.
3. The manuscript does not define what constitutes minor bile leak and how the diagnosis was
made in the study population
Title: Endo-loop or Interrupted Suture Closure of Gallbladder Remnant During Laparoscopic
Subtotal Cholecystectomy- a Retrospective Analysis of Our Experience at a High-Volume
Centre of Eastern Nepal
Version: 4 Date: 13 Mar 2025
Reviewer's report:
1. The basis for comparison of both closure techniques may be faulty if the interrupted closure is
utilized when the posterior wall of the gallbladder is not adequately mobilizable enough to enable
application of an endoloop.  It could be argued that bile leak in the cases that had interrupted
suture closure was due to the difficulty in those cases.
2. It would also be important to compare the skill level of surgeons in both groups to see if that
influenced the outcomes.
3. The manuscript does not define what constitutes minor bile leak and how the diagnosis was
made in the study population
Please review this paper.
user
Title: Endo-loop or Interrupted Suture Closure of Gallbladder Remnant During Laparoscopic
Subtotal Cholecystectomy- a Retrospective Analysis of Our Experience at a High-Volume
Centre of Eastern Nepal
Version: 4 Date: 13 Mar 2025
Reviewer's report:
1. The basis for comparison of both closure techniques may be faulty if the interrupted closure is
utilized when the posterior wall of the gallbladder is not adequately mobilizable enough to enable
application of an endoloop.  It could be argued that bile leak in the cases that had interrupted
suture closure was due to the difficulty in those cases.
2. It would also be important to compare the skill level of surgeons in both groups to see if that
influenced the outcomes.
3. The manuscript does not define what constitutes minor bile leak and how the diagnosis was
made in the study population
assistant