Reviewer's report
Title:Autoimmune Pancreatitis - A Comparative Description Highlighting North
American Experiences In Diagnosis And Management
Version: 1Date:17 December 2012
Reviewer: Raffaele Pezzilli
Reviewer's report:
The authors aimed to compare the various proposed criteria in assessing the
diagnosis of autoimmune pancreatitis. We should thank the authors for their
efforts but we have some concerns.
1. The study is retrospective and many clinical features in some patients have
been missed to definitively assess the diagnosis of autoimmune pancreatitis.
2. A number of patients were treated with steroids without a histological
diagnosis and this may explain why the Korean criteria has a sensitivity better
than the others criteria.
3. The authors should include in their comparative analysis also the new criteria
for the diagnosis of autoimmune pancreatitis Shimosegawa T, Chari ST, Frulloni
L, Kamisawa T, Kawa S, Mino-Kenudson M, Kim MH, Klöppel G, Lerch MM, Löhr
M, Notohara K, Okazaki K, Schneider A, Zhang L; International Association of
Pancreatology. International consensus diagnostic criteria for autoimmune
pancreatitis: guidelines of the International Association of Pancreatology.
Pancreas. 2011 Apr;40(3):352-8.
4. The statistical analysis is poor and a appropriate statistic should be added in
comparing the various criteria utilized for assessing the diagnosis of autoimmune
pancreatitis.
5. There are many percentages that have been missed: For example, on page 8
“Pre-treatment serology” “36/55 patients had serum IgG4 levels accessible to our
review.” the percentage should be added (65.5%).
6. Please do not initiate the period with arabical number.
Level of interest: An article of limited interest
Quality of written English: Acceptable
Statistical review: Yes, and I have assessed the statistics in my report.
Declaration of competing interests:
I declare that I have no competing interests
Reviewer's report
Title:Autoimmune Pancreatitis - A Comparative Description Highlighting North
American Experiences In Diagnosis And Management
Version: 1Date:17 December 2012
Reviewer: Raffaele Pezzilli
Reviewer's report:
The authors aimed to compare the various proposed criteria in assessing the
diagnosis of autoimmune pancreatitis. We should thank the authors for their
efforts but we have some concerns.
1. The study is retrospective and many clinical features in some patients have
been missed to definitively assess the diagnosis of autoimmune pancreatitis.
2. A number of patients were treated with steroids without a histological
diagnosis and this may explain why the Korean criteria has a sensitivity better
than the others criteria.
3. The authors should include in their comparative analysis also the new criteria
for the diagnosis of autoimmune pancreatitis Shimosegawa T, Chari ST, Frulloni
L, Kamisawa T, Kawa S, Mino-Kenudson M, Kim MH, Klöppel G, Lerch MM, Löhr
M, Notohara K, Okazaki K, Schneider A, Zhang L; International Association of
Pancreatology. International consensus diagnostic criteria for autoimmune
pancreatitis: guidelines of the International Association of Pancreatology.
Pancreas. 2011 Apr;40(3):352-8.
4. The statistical analysis is poor and a appropriate statistic should be added in
comparing the various criteria utilized for assessing the diagnosis of autoimmune
pancreatitis.
5. There are many percentages that have been missed: For example, on page 8
“Pre-treatment serology” “36/55 patients had serum IgG4 levels accessible to our
review.” the percentage should be added (65.5%).
6. Please do not initiate the period with arabical number.
Level of interest: An article of limited interest
Quality of written English: Acceptable
Statistical review: Yes, and I have assessed the statistics in my report.
Declaration of competing interests:
I declare that I have no competing interests
Please review this paper.
user
Reviewer's report
Title:Autoimmune Pancreatitis - A Comparative Description Highlighting North
American Experiences In Diagnosis And Management
Version: 1Date:17 December 2012
Reviewer: Raffaele Pezzilli
Reviewer's report:
The authors aimed to compare the various proposed criteria in assessing the
diagnosis of autoimmune pancreatitis. We should thank the authors for their
efforts but we have some concerns.
1. The study is retrospective and many clinical features in some patients have
been missed to definitively assess the diagnosis of autoimmune pancreatitis.
2. A number of patients were treated with steroids without a histological
diagnosis and this may explain why the Korean criteria has a sensitivity better
than the others criteria.
3. The authors should include in their comparative analysis also the new criteria
for the diagnosis of autoimmune pancreatitis Shimosegawa T, Chari ST, Frulloni
L, Kamisawa T, Kawa S, Mino-Kenudson M, Kim MH, Klöppel G, Lerch MM, Löhr
M, Notohara K, Okazaki K, Schneider A, Zhang L; International Association of
Pancreatology. International consensus diagnostic criteria for autoimmune
pancreatitis: guidelines of the International Association of Pancreatology.
Pancreas. 2011 Apr;40(3):352-8.
4. The statistical analysis is poor and a appropriate statistic should be added in
comparing the various criteria utilized for assessing the diagnosis of autoimmune
pancreatitis.
5. There are many percentages that have been missed: For example, on page 8
“Pre-treatment serology” “36/55 patients had serum IgG4 levels accessible to our
review.” the percentage should be added (65.5%).
6. Please do not initiate the period with arabical number.
Level of interest: An article of limited interest
Quality of written English: Acceptable
Statistical review: Yes, and I have assessed the statistics in my report.
Declaration of competing interests:
I declare that I have no competing interests
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