Reviewer's report
Title:Anticoagulant therapy for nodular regenerative hyperplasia in a
HIV-infected patient
Version: 3Date:16 November 2009
Reviewer: Vincent Mallet
Reviewer's report:
Major Compulsory Revisions: None
Minor Essential Revisions: in the Introduction is written "The central veins are
obliterated by the parietal thickening of the portal veins reducing the vascular
lumen and sinusoids are dilated." It is the obliteration of the small portal veins
that leads to the atrophy of the supplied acinus and to the hypertrophy of the
adjacent acinus. Sinusoidal dilatation is secondary to the increase in blood flow
(and not to congestion because of venous outflow blockage). Please check the
review of Reshamwala et al.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
None related to this report.
Reviewer's report
Title:Anticoagulant therapy for nodular regenerative hyperplasia in a
HIV-infected patient
Version: 3Date:16 November 2009
Reviewer: Vincent Mallet
Reviewer's report:
Major Compulsory Revisions: None
Minor Essential Revisions: in the Introduction is written "The central veins are
obliterated by the parietal thickening of the portal veins reducing the vascular
lumen and sinusoids are dilated." It is the obliteration of the small portal veins
that leads to the atrophy of the supplied acinus and to the hypertrophy of the
adjacent acinus. Sinusoidal dilatation is secondary to the increase in blood flow
(and not to congestion because of venous outflow blockage). Please check the
review of Reshamwala et al.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
None related to this report.
Please review this paper.
user
Reviewer's report
Title:Anticoagulant therapy for nodular regenerative hyperplasia in a
HIV-infected patient
Version: 3Date:16 November 2009
Reviewer: Vincent Mallet
Reviewer's report:
Major Compulsory Revisions: None
Minor Essential Revisions: in the Introduction is written "The central veins are
obliterated by the parietal thickening of the portal veins reducing the vascular
lumen and sinusoids are dilated." It is the obliteration of the small portal veins
that leads to the atrophy of the supplied acinus and to the hypertrophy of the
adjacent acinus. Sinusoidal dilatation is secondary to the increase in blood flow
(and not to congestion because of venous outflow blockage). Please check the
review of Reshamwala et al.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
None related to this report.
assistant