Reviewer's report
Title:Meta-analysis of Percutaneous Radiofrequency Ablation versus Ethanol
Injection in Hepatocellular Carcinoma.
Version: 1Date:2 February 2009
Reviewer: Guy J Maddern
Reviewer's report:
Limited data available.
Good effort to compile and analyse the data.
The quality of the studies included was a bit difficult to guage, most included
patients who appear suitable for a liver resection/trasplant (74% Childs A, 57%
solitary, mean size 2.5cm).
Perhaps the autors can clarify why these were irresectable.
The studies included are very expectedly heterogenous, but RFA results appear
unquestionably better.
Reproducible
Well written - should use more headings and subheadings especially in results
category eg. A)Safety
i) Complications
B) Use of resources
i) Hospital stay
ii)No. of sessions
iii) Cost etc.
Need statistics
Review to confirm results
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: Yes, but I do not feel adequately qualified to assess the
statistics.
Declaration of competing interests:
I declare that I have no competing interests
Reviewer's report
Title:Meta-analysis of Percutaneous Radiofrequency Ablation versus Ethanol
Injection in Hepatocellular Carcinoma.
Version: 1Date:2 February 2009
Reviewer: Guy J Maddern
Reviewer's report:
Limited data available.
Good effort to compile and analyse the data.
The quality of the studies included was a bit difficult to guage, most included
patients who appear suitable for a liver resection/trasplant (74% Childs A, 57%
solitary, mean size 2.5cm).
Perhaps the autors can clarify why these were irresectable.
The studies included are very expectedly heterogenous, but RFA results appear
unquestionably better.
Reproducible
Well written - should use more headings and subheadings especially in results
category eg. A)Safety
i) Complications
B) Use of resources
i) Hospital stay
ii)No. of sessions
iii) Cost etc.
Need statistics
Review to confirm results
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: Yes, but I do not feel adequately qualified to assess the
statistics.
Declaration of competing interests:
I declare that I have no competing interests
Please review this paper.
user
Reviewer's report
Title:Meta-analysis of Percutaneous Radiofrequency Ablation versus Ethanol
Injection in Hepatocellular Carcinoma.
Version: 1Date:2 February 2009
Reviewer: Guy J Maddern
Reviewer's report:
Limited data available.
Good effort to compile and analyse the data.
The quality of the studies included was a bit difficult to guage, most included
patients who appear suitable for a liver resection/trasplant (74% Childs A, 57%
solitary, mean size 2.5cm).
Perhaps the autors can clarify why these were irresectable.
The studies included are very expectedly heterogenous, but RFA results appear
unquestionably better.
Reproducible
Well written - should use more headings and subheadings especially in results
category eg. A)Safety
i) Complications
B) Use of resources
i) Hospital stay
ii)No. of sessions
iii) Cost etc.
Need statistics
Review to confirm results
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: Yes, but I do not feel adequately qualified to assess the
statistics.
Declaration of competing interests:
I declare that I have no competing interests
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