Title: PREDICTIVE ACCURACY OF FECAL CALPROTECTIN IN ASSESSING
CLINICAL ACTIVITY AND DISEASE SEVERITY IN PATIENTS WITH ULCERATIVE
COLITIS AND CROHN’S DISEASE
Version: 2 Date: 03 Apr 2025
Reviewer's report:
1. Approval of ethical committee and consent should have been mentioned in the materials and
methods section.
2. Predictive value of ESR and CRP in the same patients should have been evaluated and
compared with FCP for better understanding.
3. Although FCP is a noninvasive test still it is a costly test with financial implication for the
patient.
4. The FCP value was following a nonparametric distribution. Hence Spearman's correlation test
would have been a better statistical method than Pearson's correlation.
Title: PREDICTIVE ACCURACY OF FECAL CALPROTECTIN IN ASSESSING
CLINICAL ACTIVITY AND DISEASE SEVERITY IN PATIENTS WITH ULCERATIVE
COLITIS AND CROHN’S DISEASE
Version: 2 Date: 03 Apr 2025
Reviewer's report:
1. Approval of ethical committee and consent should have been mentioned in the materials and
methods section.
2. Predictive value of ESR and CRP in the same patients should have been evaluated and
compared with FCP for better understanding.
3. Although FCP is a noninvasive test still it is a costly test with financial implication for the
patient.
4. The FCP value was following a nonparametric distribution. Hence Spearman's correlation test
would have been a better statistical method than Pearson's correlation.
Please review this paper.
user
Title: PREDICTIVE ACCURACY OF FECAL CALPROTECTIN IN ASSESSING
CLINICAL ACTIVITY AND DISEASE SEVERITY IN PATIENTS WITH ULCERATIVE
COLITIS AND CROHN’S DISEASE
Version: 2 Date: 03 Apr 2025
Reviewer's report:
1. Approval of ethical committee and consent should have been mentioned in the materials and
methods section.
2. Predictive value of ESR and CRP in the same patients should have been evaluated and
compared with FCP for better understanding.
3. Although FCP is a noninvasive test still it is a costly test with financial implication for the
patient.
4. The FCP value was following a nonparametric distribution. Hence Spearman's correlation test
would have been a better statistical method than Pearson's correlation.
assistant