Title: Renal and bone side effects of long-term use of entecavir, tenofovir disoproxil fumarate,
and tenofovir alafenamide fumarate in patients with hepatitis B: A network meta-analysis
Version: 1 Date: 22 Jun 2023
Reviewer's report:
Interesting analysis, well-defined objective, systematic trials search, exclusion criteria given.
The choice for statistical method need to be justified.
Did you search statistical heterogeneity ?
Did you realised sensibility analysys (with follow-up duration) ?
The fact that the vast majority of included treated patients were from asian origin need to be
mentioned.
Blood phosphorus is only an intermediate criteria for bone damage.
Some details : p2 introduction (introductiong), anti-infectious (anti-infective), p3 1 trial (1 trials)
I recommand acceptance after answering these remarks and details corrections
Title: Renal and bone side effects of long-term use of entecavir, tenofovir disoproxil fumarate,
and tenofovir alafenamide fumarate in patients with hepatitis B: A network meta-analysis
Version: 1 Date: 22 Jun 2023
Reviewer's report:
Interesting analysis, well-defined objective, systematic trials search, exclusion criteria given.
The choice for statistical method need to be justified.
Did you search statistical heterogeneity ?
Did you realised sensibility analysys (with follow-up duration) ?
The fact that the vast majority of included treated patients were from asian origin need to be
mentioned.
Blood phosphorus is only an intermediate criteria for bone damage.
Some details : p2 introduction (introductiong), anti-infectious (anti-infective), p3 1 trial (1 trials)
I recommand acceptance after answering these remarks and details corrections
Please review this paper.
user
Title: Renal and bone side effects of long-term use of entecavir, tenofovir disoproxil fumarate,
and tenofovir alafenamide fumarate in patients with hepatitis B: A network meta-analysis
Version: 1 Date: 22 Jun 2023
Reviewer's report:
Interesting analysis, well-defined objective, systematic trials search, exclusion criteria given.
The choice for statistical method need to be justified.
Did you search statistical heterogeneity ?
Did you realised sensibility analysys (with follow-up duration) ?
The fact that the vast majority of included treated patients were from asian origin need to be
mentioned.
Blood phosphorus is only an intermediate criteria for bone damage.
Some details : p2 introduction (introductiong), anti-infectious (anti-infective), p3 1 trial (1 trials)
I recommand acceptance after answering these remarks and details corrections
assistant