Reviewer's report
Title:Lack of association between peroxisome proliferator-activated receptors
alpha and gamma2 polymorphisms and progressive liver damage in patients with
non-alcoholic fatty liver disease: a case control study
Version: 2Date:12 July 2010
Reviewer: Véronique Barbu
Reviewer's report:
Minor essential revision:
To answer to your comment 1: I do not agree with the fact that genotyping 2
SNPs by assays with Taqman probes is slower and hard working... Once the
technique is correctly done, it is faster for a lot of patients. I would appreciate if
you could introduce in the genetic part of "the materials and methods" a sentence
precising that you confirmed by sequencing the mutated patients.
I agree with all the other comments.
The manuscript has been greatly improved by the authors.
The paper is now suitable for publication.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests
Reviewer's report
Title:Lack of association between peroxisome proliferator-activated receptors
alpha and gamma2 polymorphisms and progressive liver damage in patients with
non-alcoholic fatty liver disease: a case control study
Version: 2Date:12 July 2010
Reviewer: Véronique Barbu
Reviewer's report:
Minor essential revision:
To answer to your comment 1: I do not agree with the fact that genotyping 2
SNPs by assays with Taqman probes is slower and hard working... Once the
technique is correctly done, it is faster for a lot of patients. I would appreciate if
you could introduce in the genetic part of "the materials and methods" a sentence
precising that you confirmed by sequencing the mutated patients.
I agree with all the other comments.
The manuscript has been greatly improved by the authors.
The paper is now suitable for publication.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests
Please review this paper.
user
Reviewer's report
Title:Lack of association between peroxisome proliferator-activated receptors
alpha and gamma2 polymorphisms and progressive liver damage in patients with
non-alcoholic fatty liver disease: a case control study
Version: 2Date:12 July 2010
Reviewer: Véronique Barbu
Reviewer's report:
Minor essential revision:
To answer to your comment 1: I do not agree with the fact that genotyping 2
SNPs by assays with Taqman probes is slower and hard working... Once the
technique is correctly done, it is faster for a lot of patients. I would appreciate if
you could introduce in the genetic part of "the materials and methods" a sentence
precising that you confirmed by sequencing the mutated patients.
I agree with all the other comments.
The manuscript has been greatly improved by the authors.
The paper is now suitable for publication.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests
assistant