Title: Long Transparent Cap-Assisted Clip Closure Technique: A New Choice for
Gastrointestinal Defect Closure
Version: 2 Date: 06 Feb 2025
Reviewer:  Takeshi Ohki
Reviewer's report:
(1) This paper compares the long transparent cap-assisted clip closure technique (LTCCC)
advocated by the authors with the conventional purse-string suture (PSS). As the authors
mention, the technique of closing with an endoscopic clip using a cap and suction has been a
standard procedure for some time, and fixing the tip of the cap in place or using a hard cap with
a nail are also techniques that have been used. The LTCCC technique that the authors advocate
is not a novel technique, as can be seen in Figure 1, but is just one of the arrangements.
(2) The background of LTCCC and PSS is different, and PSS is thought to be selected for larger
lesions and mucosal defects. Therefore, in order to perform accurate matching using propensity
score matching (PSM), it is necessary to include the size of the tumour or specimen, or the size
of the mucosal defect, in the evaluation.
(3) In order to convince readers, it would be preferable to compare the conventional method
using a cap with the authors' modifications with PSS, or to compare a simple endoscopic closure
technique that does not use a cap or PSS.
Title: Long Transparent Cap-Assisted Clip Closure Technique: A New Choice for
Gastrointestinal Defect Closure
Version: 2 Date: 06 Feb 2025
Reviewer:  Takeshi Ohki
Reviewer's report:
(1) This paper compares the long transparent cap-assisted clip closure technique (LTCCC)
advocated by the authors with the conventional purse-string suture (PSS). As the authors
mention, the technique of closing with an endoscopic clip using a cap and suction has been a
standard procedure for some time, and fixing the tip of the cap in place or using a hard cap with
a nail are also techniques that have been used. The LTCCC technique that the authors advocate
is not a novel technique, as can be seen in Figure 1, but is just one of the arrangements.
(2) The background of LTCCC and PSS is different, and PSS is thought to be selected for larger
lesions and mucosal defects. Therefore, in order to perform accurate matching using propensity
score matching (PSM), it is necessary to include the size of the tumour or specimen, or the size
of the mucosal defect, in the evaluation.
(3) In order to convince readers, it would be preferable to compare the conventional method
using a cap with the authors' modifications with PSS, or to compare a simple endoscopic closure
technique that does not use a cap or PSS.
Please review this paper.
user
Title: Long Transparent Cap-Assisted Clip Closure Technique: A New Choice for
Gastrointestinal Defect Closure
Version: 2 Date: 06 Feb 2025
Reviewer:  Takeshi Ohki
Reviewer's report:
(1) This paper compares the long transparent cap-assisted clip closure technique (LTCCC)
advocated by the authors with the conventional purse-string suture (PSS). As the authors
mention, the technique of closing with an endoscopic clip using a cap and suction has been a
standard procedure for some time, and fixing the tip of the cap in place or using a hard cap with
a nail are also techniques that have been used. The LTCCC technique that the authors advocate
is not a novel technique, as can be seen in Figure 1, but is just one of the arrangements.
(2) The background of LTCCC and PSS is different, and PSS is thought to be selected for larger
lesions and mucosal defects. Therefore, in order to perform accurate matching using propensity
score matching (PSM), it is necessary to include the size of the tumour or specimen, or the size
of the mucosal defect, in the evaluation.
(3) In order to convince readers, it would be preferable to compare the conventional method
using a cap with the authors' modifications with PSS, or to compare a simple endoscopic closure
technique that does not use a cap or PSS.
assistant