Reviewer ’s report  
 
Title: Hepatocellular carcinoma in Adult Thalassemia patients: An expert opinion based on  
current evidence  
 
Version: 1 Date: 23 Apr 2020  
 
Reviewer's report:  
 
Having read the revised manuscript, I will not deny the pos sibility of publication because of 
some different opinion I have on the topic, because It is obvious that being TH rare, in absence 
of evidence, different authors can have different points of view.  
 
However, in my opinion some issues must be corrected:  
 
1) please, avoid to underline (both in the abstract and main text) that the choice of the panel was 
the most authorative possible: someone with both known estensive expecience and pubblications 
on the topic could find this inconvenient and disappointing.  
2) thromboebolic prophilaxis should be the same as in non TH: no clear evidence suggests the 
opposite.  
 
Moreover, Reference 104 is a repetition.  
 
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Acceptable  
 
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following questions:  
 
1. Have you in the past five years received reimbursements, fees, funding,  or salary from an  
organisation that may in any way gain or lose financially from the publication of this  
manuscript, either now or in the future?  
 
2. Do you hold any stocks or shares in an organisation that may in any way gain or lose  
financially from the publication of this manuscript, either now or in the future?  
 
3. Do you hold or are you currently applying for any patents relating to the content of the  
manuscript?  
 
4. Have you received reimbursements, fees, funding, or salary from an organization that 
holds or has applied for patents relating to the content of the manuscript?  
 
5. Do you have any other financial competing interests?  
 
6. Do you have any non -financial competing interests in relation to this paper?  
 
If you can answer no to all of the above, write  'I declare that I have no competing interests' 
below.  If your reply is yes to any, please give details below.  
 
none  
 
I agree to the open peer review policy of the journal. I understand that my name will be included  
on my report to the authors and, if the manuscript is accepted for publication, my named report  
including any attachments I upload will be posted on the website along with the authors'  
responses. I agree for my report to be made available under an Open Acces s Creative Commons  
CC-BY license ( http://creativecommons.org/licenses/by/4.0/ ). I understand that any comments  
which I do not wish to be included in my named report can be included as confidential comments  
to the editors, which will not be published.  
 
I agree to the open peer review policy of the journal  
Reviewer ’s report  
 
Title: Hepatocellular carcinoma in Adult Thalassemia patients: An expert opinion based on  
current evidence  
 
Version: 1 Date: 23 Apr 2020  
 
Reviewer's report:  
 
Having read the revised manuscript, I will not deny the pos sibility of publication because of 
some different opinion I have on the topic, because It is obvious that being TH rare, in absence 
of evidence, different authors can have different points of view.  
 
However, in my opinion some issues must be corrected:  
 
1) please, avoid to underline (both in the abstract and main text) that the choice of the panel was 
the most authorative possible: someone with both known estensive expecience and pubblications 
on the topic could find this inconvenient and disappointing.  
2) thromboebolic prophilaxis should be the same as in non TH: no clear evidence suggests the 
opposite.  
 
Moreover, Reference 104 is a repetition.  
 
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Acceptable  
 
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following questions:  
 
1. Have you in the past five years received reimbursements, fees, funding,  or salary from an  
organisation that may in any way gain or lose financially from the publication of this  
manuscript, either now or in the future?  
 
2. Do you hold any stocks or shares in an organisation that may in any way gain or lose  
financially from the publication of this manuscript, either now or in the future?  
 
3. Do you hold or are you currently applying for any patents relating to the content of the  
manuscript?  
 
4. Have you received reimbursements, fees, funding, or salary from an organization that 
holds or has applied for patents relating to the content of the manuscript?  
 
5. Do you have any other financial competing interests?  
 
6. Do you have any non -financial competing interests in relation to this paper?  
 
If you can answer no to all of the above, write  'I declare that I have no competing interests' 
below.  If your reply is yes to any, please give details below.  
 
none  
 
I agree to the open peer review policy of the journal. I understand that my name will be included  
on my report to the authors and, if the manuscript is accepted for publication, my named report  
including any attachments I upload will be posted on the website along with the authors'  
responses. I agree for my report to be made available under an Open Acces s Creative Commons  
CC-BY license ( http://creativecommons.org/licenses/by/4.0/ ). I understand that any comments  
which I do not wish to be included in my named report can be included as confidential comments  
to the editors, which will not be published.  
 
I agree to the open peer review policy of the journal  
Please review this paper.
user
Reviewer ’s report  
 
Title: Hepatocellular carcinoma in Adult Thalassemia patients: An expert opinion based on  
current evidence  
 
Version: 1 Date: 23 Apr 2020  
 
Reviewer's report:  
 
Having read the revised manuscript, I will not deny the pos sibility of publication because of 
some different opinion I have on the topic, because It is obvious that being TH rare, in absence 
of evidence, different authors can have different points of view.  
 
However, in my opinion some issues must be corrected:  
 
1) please, avoid to underline (both in the abstract and main text) that the choice of the panel was 
the most authorative possible: someone with both known estensive expecience and pubblications 
on the topic could find this inconvenient and disappointing.  
2) thromboebolic prophilaxis should be the same as in non TH: no clear evidence suggests the 
opposite.  
 
Moreover, Reference 104 is a repetition.  
 
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Acceptable  
 
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following questions:  
 
1. Have you in the past five years received reimbursements, fees, funding,  or salary from an  
organisation that may in any way gain or lose financially from the publication of this  
manuscript, either now or in the future?  
 
2. Do you hold any stocks or shares in an organisation that may in any way gain or lose  
financially from the publication of this manuscript, either now or in the future?  
 
3. Do you hold or are you currently applying for any patents relating to the content of the  
manuscript?  
 
4. Have you received reimbursements, fees, funding, or salary from an organization that 
holds or has applied for patents relating to the content of the manuscript?  
 
5. Do you have any other financial competing interests?  
 
6. Do you have any non -financial competing interests in relation to this paper?  
 
If you can answer no to all of the above, write  'I declare that I have no competing interests' 
below.  If your reply is yes to any, please give details below.  
 
none  
 
I agree to the open peer review policy of the journal. I understand that my name will be included  
on my report to the authors and, if the manuscript is accepted for publication, my named report  
including any attachments I upload will be posted on the website along with the authors'  
responses. I agree for my report to be made available under an Open Acces s Creative Commons  
CC-BY license ( http://creativecommons.org/licenses/by/4.0/ ). I understand that any comments  
which I do not wish to be included in my named report can be included as confidential comments  
to the editors, which will not be published.  
 
I agree to the open peer review policy of the journal  
assistant