Title: Preliminary Study on the Diagnostic Value of LEAP-2 and CK18 in Biopsy-Proven
MAFLD
Version: 2 Date: 09 Dec 2023
Reviewer's report:
This study assesses CK18 M30/M65 and LEAP-2 as potential biomarkers for diagnosing
Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD). Positive correlations with
ALT and AST are observed, with CK18 M65 recommended for screening and LEAP-2 for
differential diagnosis.
Some suggestions :
1. Clarify the clinical relevance of chosen biomarkers.
2, Address study limitations and propose future research directions.
3. Provide concise demographic characteristics of the study population.
4. Discuss potential implications for clinical practice.
Title: Preliminary Study on the Diagnostic Value of LEAP-2 and CK18 in Biopsy-Proven
MAFLD
Version: 2 Date: 09 Dec 2023
Reviewer's report:
This study assesses CK18 M30/M65 and LEAP-2 as potential biomarkers for diagnosing
Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD). Positive correlations with
ALT and AST are observed, with CK18 M65 recommended for screening and LEAP-2 for
differential diagnosis.
Some suggestions :
1. Clarify the clinical relevance of chosen biomarkers.
2, Address study limitations and propose future research directions.
3. Provide concise demographic characteristics of the study population.
4. Discuss potential implications for clinical practice.
Please review this paper.
user
Title: Preliminary Study on the Diagnostic Value of LEAP-2 and CK18 in Biopsy-Proven
MAFLD
Version: 2 Date: 09 Dec 2023
Reviewer's report:
This study assesses CK18 M30/M65 and LEAP-2 as potential biomarkers for diagnosing
Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD). Positive correlations with
ALT and AST are observed, with CK18 M65 recommended for screening and LEAP-2 for
differential diagnosis.
Some suggestions :
1. Clarify the clinical relevance of chosen biomarkers.
2, Address study limitations and propose future research directions.
3. Provide concise demographic characteristics of the study population.
4. Discuss potential implications for clinical practice.
assistant