Reviewer's report
Title:Keratin 8 variants and prognosis of patients with alcoholic cirrhosis
Version: 1Date:14 August 2012
Reviewer: Johannes Haybaeck
Reviewer's report:
Review for BMC Gastroenterology
Manuscript entitled: "Keratin 8 variants and prognosis of patients with alcoholic
cirrhosis"
Dear colleague,
it was interesting to review the article entitled "Keratin 8 variants and prognosis of
patients with alcoholic cirrhosis" by Valentyn Usachov et al. There the authors
aimed at analyzing the prognostic impact of K8 variants. They basically found
negative results. As the work was conducted in an accurate and logical manner
these data are important, and are another puzzle stone for the understanding of
intermediate filament biology, liver integrity and hepatic physiology.
Overall the study was thoroughly designed and conducted. The questions raised
by the authors are relevant and therefore this nice piece of work is appropriate
for publication in BMC Gastroenterology. Only maybe the title could be a bit more
informative providing information about the results.
Level of interest: An exceptional article
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests.
Reviewer's report
Title:Keratin 8 variants and prognosis of patients with alcoholic cirrhosis
Version: 1Date:14 August 2012
Reviewer: Johannes Haybaeck
Reviewer's report:
Review for BMC Gastroenterology
Manuscript entitled: "Keratin 8 variants and prognosis of patients with alcoholic
cirrhosis"
Dear colleague,
it was interesting to review the article entitled "Keratin 8 variants and prognosis of
patients with alcoholic cirrhosis" by Valentyn Usachov et al. There the authors
aimed at analyzing the prognostic impact of K8 variants. They basically found
negative results. As the work was conducted in an accurate and logical manner
these data are important, and are another puzzle stone for the understanding of
intermediate filament biology, liver integrity and hepatic physiology.
Overall the study was thoroughly designed and conducted. The questions raised
by the authors are relevant and therefore this nice piece of work is appropriate
for publication in BMC Gastroenterology. Only maybe the title could be a bit more
informative providing information about the results.
Level of interest: An exceptional article
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests.
Please review this paper.
user
Reviewer's report
Title:Keratin 8 variants and prognosis of patients with alcoholic cirrhosis
Version: 1Date:14 August 2012
Reviewer: Johannes Haybaeck
Reviewer's report:
Review for BMC Gastroenterology
Manuscript entitled: "Keratin 8 variants and prognosis of patients with alcoholic
cirrhosis"
Dear colleague,
it was interesting to review the article entitled "Keratin 8 variants and prognosis of
patients with alcoholic cirrhosis" by Valentyn Usachov et al. There the authors
aimed at analyzing the prognostic impact of K8 variants. They basically found
negative results. As the work was conducted in an accurate and logical manner
these data are important, and are another puzzle stone for the understanding of
intermediate filament biology, liver integrity and hepatic physiology.
Overall the study was thoroughly designed and conducted. The questions raised
by the authors are relevant and therefore this nice piece of work is appropriate
for publication in BMC Gastroenterology. Only maybe the title could be a bit more
informative providing information about the results.
Level of interest: An exceptional article
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests.
assistant