Title: Eubiotic effect of rifaximin is associated with decreasing abdominal pain in symptomatic
uncomplicated diverticular disease: results from an observational cohort study
Version: 0 Date: 04 Jan 2023
Reviewer:  Francesco Roscio
Reviewer's report:
The topic is interesting, as it scientifically analyzes the rationale of a therapy too often prescribed
on an empirical basis. Congratulations to the authors for having pursued an observation period
of 6 months.
The paper was quite well written, both the methodology and the statistical analysis are correct.
It just needs some linguistic revisions.
However, I would like to focus on the size of the analyzed cohort.
A series of 12 patients is small. A patient outflow of nearly 50% is significant.
I leave to the Editor the decision whether or not to publish a paper with such low power.
If this aspect does not constitute a limitation, nothing prevents me from publishing it.
Title: Eubiotic effect of rifaximin is associated with decreasing abdominal pain in symptomatic
uncomplicated diverticular disease: results from an observational cohort study
Version: 0 Date: 04 Jan 2023
Reviewer:  Francesco Roscio
Reviewer's report:
The topic is interesting, as it scientifically analyzes the rationale of a therapy too often prescribed
on an empirical basis. Congratulations to the authors for having pursued an observation period
of 6 months.
The paper was quite well written, both the methodology and the statistical analysis are correct.
It just needs some linguistic revisions.
However, I would like to focus on the size of the analyzed cohort.
A series of 12 patients is small. A patient outflow of nearly 50% is significant.
I leave to the Editor the decision whether or not to publish a paper with such low power.
If this aspect does not constitute a limitation, nothing prevents me from publishing it.
Please review this paper.
user
Title: Eubiotic effect of rifaximin is associated with decreasing abdominal pain in symptomatic
uncomplicated diverticular disease: results from an observational cohort study
Version: 0 Date: 04 Jan 2023
Reviewer:  Francesco Roscio
Reviewer's report:
The topic is interesting, as it scientifically analyzes the rationale of a therapy too often prescribed
on an empirical basis. Congratulations to the authors for having pursued an observation period
of 6 months.
The paper was quite well written, both the methodology and the statistical analysis are correct.
It just needs some linguistic revisions.
However, I would like to focus on the size of the analyzed cohort.
A series of 12 patients is small. A patient outflow of nearly 50% is significant.
I leave to the Editor the decision whether or not to publish a paper with such low power.
If this aspect does not constitute a limitation, nothing prevents me from publishing it.
assistant