Title: Role of endoscopic ultrasonography for differential diagnosis of upper gastrointestinal
submucosal lesions
Version: 0 Date: 05 Jul 2021
Reviewer's report:
The authors presented their experience with diagnostic B mode EUS in the differential diagnosis
of SMLs.
1) The title should be changed to "...differential diagnosis..."
2) Introduction, line 59. It is incorrect to state that identification of SMLs with endoscopy is
difficult. You may want to state "Differential diagnosis of...is difficult"
3) Line 65: I do not understand the term "hierarchal" here. Maybe you want to say "wall layer
structure"?
4) Methods, line 90: please replace "microprobe" with "miniprobe"
5) Line 93: water infusion does not sound correct. I would write "lumen filling with water"
6) Results, line 125: please replace "pathologies"  with "histological types"
7) Line 155, please amend as follows: "Sensitivity, specificity and predictive value of the
originating layer on EUS to determine the pathological nature of the submucosal lesions"
8) Discussion: please add a paragraph to discuss the limitations of the current study.
In particular, I would quote:
a) retrospective design;
b) the lack of CH-EUS (please add some reference in this regard, e.g. Kamata K, Takenaka
M, Kitano M, et al. Contrast-enhanced harmonic endoscopic ultrasonography for differential
diagnosis of submucosal tumors of the upper gastrointestinal tract. Journal of Gastroenterology
and Hepatology (Australia) 2017;32:1686-1692.);
c) the lack of EUS-FNA/B (you can cite: Jenssen, C., Hocke, M., Fusaroli, P., et al. EFSUMB
Guidelines on Interventional Ultrasound (INVUS), Part IV - EUS-guided interventions:
General Aspects and EUS-guided Sampling (Short Version). Ultraschall in der Medizin
2016;37:157-169.)
9) Please go through your text from A to Z to revise several language issues that require polishing
Title: Role of endoscopic ultrasonography for differential diagnosis of upper gastrointestinal
submucosal lesions
Version: 0 Date: 05 Jul 2021
Reviewer's report:
The authors presented their experience with diagnostic B mode EUS in the differential diagnosis
of SMLs.
1) The title should be changed to "...differential diagnosis..."
2) Introduction, line 59. It is incorrect to state that identification of SMLs with endoscopy is
difficult. You may want to state "Differential diagnosis of...is difficult"
3) Line 65: I do not understand the term "hierarchal" here. Maybe you want to say "wall layer
structure"?
4) Methods, line 90: please replace "microprobe" with "miniprobe"
5) Line 93: water infusion does not sound correct. I would write "lumen filling with water"
6) Results, line 125: please replace "pathologies"  with "histological types"
7) Line 155, please amend as follows: "Sensitivity, specificity and predictive value of the
originating layer on EUS to determine the pathological nature of the submucosal lesions"
8) Discussion: please add a paragraph to discuss the limitations of the current study.
In particular, I would quote:
a) retrospective design;
b) the lack of CH-EUS (please add some reference in this regard, e.g. Kamata K, Takenaka
M, Kitano M, et al. Contrast-enhanced harmonic endoscopic ultrasonography for differential
diagnosis of submucosal tumors of the upper gastrointestinal tract. Journal of Gastroenterology
and Hepatology (Australia) 2017;32:1686-1692.);
c) the lack of EUS-FNA/B (you can cite: Jenssen, C., Hocke, M., Fusaroli, P., et al. EFSUMB
Guidelines on Interventional Ultrasound (INVUS), Part IV - EUS-guided interventions:
General Aspects and EUS-guided Sampling (Short Version). Ultraschall in der Medizin
2016;37:157-169.)
9) Please go through your text from A to Z to revise several language issues that require polishing
Please review this paper.
user
Title: Role of endoscopic ultrasonography for differential diagnosis of upper gastrointestinal
submucosal lesions
Version: 0 Date: 05 Jul 2021
Reviewer's report:
The authors presented their experience with diagnostic B mode EUS in the differential diagnosis
of SMLs.
1) The title should be changed to "...differential diagnosis..."
2) Introduction, line 59. It is incorrect to state that identification of SMLs with endoscopy is
difficult. You may want to state "Differential diagnosis of...is difficult"
3) Line 65: I do not understand the term "hierarchal" here. Maybe you want to say "wall layer
structure"?
4) Methods, line 90: please replace "microprobe" with "miniprobe"
5) Line 93: water infusion does not sound correct. I would write "lumen filling with water"
6) Results, line 125: please replace "pathologies"  with "histological types"
7) Line 155, please amend as follows: "Sensitivity, specificity and predictive value of the
originating layer on EUS to determine the pathological nature of the submucosal lesions"
8) Discussion: please add a paragraph to discuss the limitations of the current study.
In particular, I would quote:
a) retrospective design;
b) the lack of CH-EUS (please add some reference in this regard, e.g. Kamata K, Takenaka
M, Kitano M, et al. Contrast-enhanced harmonic endoscopic ultrasonography for differential
diagnosis of submucosal tumors of the upper gastrointestinal tract. Journal of Gastroenterology
and Hepatology (Australia) 2017;32:1686-1692.);
c) the lack of EUS-FNA/B (you can cite: Jenssen, C., Hocke, M., Fusaroli, P., et al. EFSUMB
Guidelines on Interventional Ultrasound (INVUS), Part IV - EUS-guided interventions:
General Aspects and EUS-guided Sampling (Short Version). Ultraschall in der Medizin
2016;37:157-169.)
9) Please go through your text from A to Z to revise several language issues that require polishing
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