Title: Not All Carotenoids Can Reduce the Risk of Gastric Cancer: A Systematic Review with
Meta-Analysis
Version: 1 Date: 30 Dec 2023
Reviewer's report:
The paper, entitled: Not All Carotenoids Can Reduce the Risk of Gastric Cancer: A Systematic
Review with Meta-Analysis  well written approximately, but it needs some major revision as
follow as:
Please Check.
-Abstract: The statistical model used and the name of the statistical package should be
mentioned.
-Methods: 2.1.2 Interventions  (I): The included studies were observational, so intervention has
no meaning. It is better to use exposure in parentheses according to PICOT's strategy
-2.1.3 Control (C): This part of PICOTS is also related to the control group (placebo or routine
treatment) in interventional studies (RCTs) and has no meaning in observational studies, and
this item should be removed too!
-The results of reporting bias (quality of studies) are not mentioned in the text.
-The general charachetertics s of the included studies  must be mentioned as a table. (name of
author, year of publication, place of publication, sample size, type of study, and quality of study)
and other necessary information.
-Figure 5: Why is the funnel plot only in the subtype of a carotenoid has been reported? It is better
to report this result by type of studies separately, just as you have separated the results according
to type of studies. In total, two graphs are enough. Funnel plot for case control and funnel plot
for cohort-studies. so, the results of this section are needed to be revised in the related text
Title: Not All Carotenoids Can Reduce the Risk of Gastric Cancer: A Systematic Review with
Meta-Analysis
Version: 1 Date: 30 Dec 2023
Reviewer's report:
The paper, entitled: Not All Carotenoids Can Reduce the Risk of Gastric Cancer: A Systematic
Review with Meta-Analysis  well written approximately, but it needs some major revision as
follow as:
Please Check.
-Abstract: The statistical model used and the name of the statistical package should be
mentioned.
-Methods: 2.1.2 Interventions  (I): The included studies were observational, so intervention has
no meaning. It is better to use exposure in parentheses according to PICOT's strategy
-2.1.3 Control (C): This part of PICOTS is also related to the control group (placebo or routine
treatment) in interventional studies (RCTs) and has no meaning in observational studies, and
this item should be removed too!
-The results of reporting bias (quality of studies) are not mentioned in the text.
-The general charachetertics s of the included studies  must be mentioned as a table. (name of
author, year of publication, place of publication, sample size, type of study, and quality of study)
and other necessary information.
-Figure 5: Why is the funnel plot only in the subtype of a carotenoid has been reported? It is better
to report this result by type of studies separately, just as you have separated the results according
to type of studies. In total, two graphs are enough. Funnel plot for case control and funnel plot
for cohort-studies. so, the results of this section are needed to be revised in the related text
Please review this paper.
user
Title: Not All Carotenoids Can Reduce the Risk of Gastric Cancer: A Systematic Review with
Meta-Analysis
Version: 1 Date: 30 Dec 2023
Reviewer's report:
The paper, entitled: Not All Carotenoids Can Reduce the Risk of Gastric Cancer: A Systematic
Review with Meta-Analysis  well written approximately, but it needs some major revision as
follow as:
Please Check.
-Abstract: The statistical model used and the name of the statistical package should be
mentioned.
-Methods: 2.1.2 Interventions  (I): The included studies were observational, so intervention has
no meaning. It is better to use exposure in parentheses according to PICOT's strategy
-2.1.3 Control (C): This part of PICOTS is also related to the control group (placebo or routine
treatment) in interventional studies (RCTs) and has no meaning in observational studies, and
this item should be removed too!
-The results of reporting bias (quality of studies) are not mentioned in the text.
-The general charachetertics s of the included studies  must be mentioned as a table. (name of
author, year of publication, place of publication, sample size, type of study, and quality of study)
and other necessary information.
-Figure 5: Why is the funnel plot only in the subtype of a carotenoid has been reported? It is better
to report this result by type of studies separately, just as you have separated the results according
to type of studies. In total, two graphs are enough. Funnel plot for case control and funnel plot
for cohort-studies. so, the results of this section are needed to be revised in the related text
assistant