Title: Natural history of decompensated cirrhosis with serum hepatitis B DNA < 2000IU/mL:
a retrospective study
Version: 1 Date: 11 Sep 2022
Reviewer:  Ponsiano Ocama
Reviewer's report:
This is a well written manuscript on an important subject. In most cases patients with LLV if
not cirrhotic are not treated as this may also mean inactive infection especially in those HBeAg
negative and normal liver enzymes. Moreover, occult HBV with negative HBsAg but detected
viraemic may also progress.
This study clearly shows that those alreay with complications, one may find a low level viraemia
but this is still not innocent.
This paper should be published as is
Title: Natural history of decompensated cirrhosis with serum hepatitis B DNA < 2000IU/mL:
a retrospective study
Version: 1 Date: 11 Sep 2022
Reviewer:  Ponsiano Ocama
Reviewer's report:
This is a well written manuscript on an important subject. In most cases patients with LLV if
not cirrhotic are not treated as this may also mean inactive infection especially in those HBeAg
negative and normal liver enzymes. Moreover, occult HBV with negative HBsAg but detected
viraemic may also progress.
This study clearly shows that those alreay with complications, one may find a low level viraemia
but this is still not innocent.
This paper should be published as is
Please review this paper.
user
Title: Natural history of decompensated cirrhosis with serum hepatitis B DNA < 2000IU/mL:
a retrospective study
Version: 1 Date: 11 Sep 2022
Reviewer:  Ponsiano Ocama
Reviewer's report:
This is a well written manuscript on an important subject. In most cases patients with LLV if
not cirrhotic are not treated as this may also mean inactive infection especially in those HBeAg
negative and normal liver enzymes. Moreover, occult HBV with negative HBsAg but detected
viraemic may also progress.
This study clearly shows that those alreay with complications, one may find a low level viraemia
but this is still not innocent.
This paper should be published as is
assistant