Title: Evaluation of Double-Balloon Enteroscopy in the Management of Type 1 Small Bowel
Vascular Lesions (angioectasia): A Retrospective Cohort Study
Version: 4 Date: 14 Dec 2024
Reviewer's report:
Dear authors,
Thanks for your responses
This study presents a comprehensive analysis of small bowel vascular lesions (SBVLs)
diagnosed through double-balloon enteroscopy (DBE) and their management. It highlights
the prevalence and clinical relevance of small bowel bleeding, with SBVLs, especially
angioectasias, being a significant contributor. The study also emphasizes the role of DBE not
only in diagnosing but also in providing therapeutic interventions for SBVLs, including various
endoscopic techniques such as argon plasma coagulation, injection therapy, and clipping.
The study's findings are particularly important for understanding the risk factors associated
with recurrent bleeding in SBVL patients. Anticoagulant use, cardiovascular disease, chronic
renal failure, diabetes mellitus, and specific lesion locations, such as in the duodenum and
ileum, were identified as significant predictors of rebleeding. These insights contribute to better
clinical decision-making by providing predictors for recurrence, which can guide the intensity
and frequency of follow-up treatments.
Additionally, the study effectively addresses the lack of standardized terminology in the field by
using the Yano classification for SBVLs. This approach helps to clarify lesion categorization,
reducing ambiguity in diagnosis and treatment planning.
Overall, the research provides valuable data that can enhance patient outcomes through
improved identification, treatment, and monitoring of SBVLs, especially those that are prone to
rebleeding. However, the retrospective nature of the study, and the fact that it was conducted in
a single center, suggests that further multicenter, prospective studies may be needed to validate
these findings and refine treatment protocols.
Title: Evaluation of Double-Balloon Enteroscopy in the Management of Type 1 Small Bowel
Vascular Lesions (angioectasia): A Retrospective Cohort Study
Version: 4 Date: 14 Dec 2024
Reviewer's report:
Dear authors,
Thanks for your responses
This study presents a comprehensive analysis of small bowel vascular lesions (SBVLs)
diagnosed through double-balloon enteroscopy (DBE) and their management. It highlights
the prevalence and clinical relevance of small bowel bleeding, with SBVLs, especially
angioectasias, being a significant contributor. The study also emphasizes the role of DBE not
only in diagnosing but also in providing therapeutic interventions for SBVLs, including various
endoscopic techniques such as argon plasma coagulation, injection therapy, and clipping.
The study's findings are particularly important for understanding the risk factors associated
with recurrent bleeding in SBVL patients. Anticoagulant use, cardiovascular disease, chronic
renal failure, diabetes mellitus, and specific lesion locations, such as in the duodenum and
ileum, were identified as significant predictors of rebleeding. These insights contribute to better
clinical decision-making by providing predictors for recurrence, which can guide the intensity
and frequency of follow-up treatments.
Additionally, the study effectively addresses the lack of standardized terminology in the field by
using the Yano classification for SBVLs. This approach helps to clarify lesion categorization,
reducing ambiguity in diagnosis and treatment planning.
Overall, the research provides valuable data that can enhance patient outcomes through
improved identification, treatment, and monitoring of SBVLs, especially those that are prone to
rebleeding. However, the retrospective nature of the study, and the fact that it was conducted in
a single center, suggests that further multicenter, prospective studies may be needed to validate
these findings and refine treatment protocols.
Please review this paper.
user
Title: Evaluation of Double-Balloon Enteroscopy in the Management of Type 1 Small Bowel
Vascular Lesions (angioectasia): A Retrospective Cohort Study
Version: 4 Date: 14 Dec 2024
Reviewer's report:
Dear authors,
Thanks for your responses
This study presents a comprehensive analysis of small bowel vascular lesions (SBVLs)
diagnosed through double-balloon enteroscopy (DBE) and their management. It highlights
the prevalence and clinical relevance of small bowel bleeding, with SBVLs, especially
angioectasias, being a significant contributor. The study also emphasizes the role of DBE not
only in diagnosing but also in providing therapeutic interventions for SBVLs, including various
endoscopic techniques such as argon plasma coagulation, injection therapy, and clipping.
The study's findings are particularly important for understanding the risk factors associated
with recurrent bleeding in SBVL patients. Anticoagulant use, cardiovascular disease, chronic
renal failure, diabetes mellitus, and specific lesion locations, such as in the duodenum and
ileum, were identified as significant predictors of rebleeding. These insights contribute to better
clinical decision-making by providing predictors for recurrence, which can guide the intensity
and frequency of follow-up treatments.
Additionally, the study effectively addresses the lack of standardized terminology in the field by
using the Yano classification for SBVLs. This approach helps to clarify lesion categorization,
reducing ambiguity in diagnosis and treatment planning.
Overall, the research provides valuable data that can enhance patient outcomes through
improved identification, treatment, and monitoring of SBVLs, especially those that are prone to
rebleeding. However, the retrospective nature of the study, and the fact that it was conducted in
a single center, suggests that further multicenter, prospective studies may be needed to validate
these findings and refine treatment protocols.
assistant