Title: Severe Combined Immunodeficiency: Improved survival leading to detection of
underlying liver disease
Version: 3 Date: 30 Dec 2022
Reviewer's report:
I find merit in the present study.
Non immunological effects of ADA SCID represent important aspects in the clinical evaluation
and management of the patients and also in assessing post-therapy life expectancy. Even if the
study presents a small cohort evaluation due to the rarity of pathology, the authors conclusions
are well detailed and convincing.
In my opinion it could be accepted for publication on BMC Gastroenterology with just minor
correction
Correct the sentence pag 15 line 11 “inactivated S-adenosylhomocysteine hydrolase (SAH)
enzyme causing…”
Title: Severe Combined Immunodeficiency: Improved survival leading to detection of
underlying liver disease
Version: 3 Date: 30 Dec 2022
Reviewer's report:
I find merit in the present study.
Non immunological effects of ADA SCID represent important aspects in the clinical evaluation
and management of the patients and also in assessing post-therapy life expectancy. Even if the
study presents a small cohort evaluation due to the rarity of pathology, the authors conclusions
are well detailed and convincing.
In my opinion it could be accepted for publication on BMC Gastroenterology with just minor
correction
Correct the sentence pag 15 line 11 “inactivated S-adenosylhomocysteine hydrolase (SAH)
enzyme causing…”
Please review this paper.
user
Title: Severe Combined Immunodeficiency: Improved survival leading to detection of
underlying liver disease
Version: 3 Date: 30 Dec 2022
Reviewer's report:
I find merit in the present study.
Non immunological effects of ADA SCID represent important aspects in the clinical evaluation
and management of the patients and also in assessing post-therapy life expectancy. Even if the
study presents a small cohort evaluation due to the rarity of pathology, the authors conclusions
are well detailed and convincing.
In my opinion it could be accepted for publication on BMC Gastroenterology with just minor
correction
Correct the sentence pag 15 line 11 “inactivated S-adenosylhomocysteine hydrolase (SAH)
enzyme causing…”
assistant