Title: Intriguing findings of liver fibrosis following Covid-19
Version: 1 Date: 10 Jun 2021
Reviewer's report:
This study tackles an important issue related to COVID-19 which assess liver fibrosis in
COVID-19 patients by serum HA and FIB-4 and to detect their relationship with liver function
tests, inflammatory markers, and blood oxygen saturation irrespective to underlying liver
disease.
My comments are.
1- In abstract section, there is a contradictory between P-value mentioned in sentence" HA
was higher in patients with higher liver stiffness (rs=0.30, p<0.05)" and in the sentence" SWE
correlated with HA (rs=0.30, p=0.021)". Please revise.
2- In introduction section, reference 5 [e.g. 5] ……….please omit "e.g".
3- In method section, the abbreviation of (RT-PCT) in the sentence "diagnosis of SARS-CoV-2
infection………."  Please correct to "RT-PCR".
4- Mention the unit of each parameter of FIB-4 equation.
5- In result section.
1- Author mentioned HA correlated with AST (rs=0.60, p<0.001) but r = 0.52 in the table 2
please revise.
2- Author mentioned HA correlated with FIB-4 (r=0.27) but r = 0.5 in the table 2 please revise.
3-  The sentence is not clear "HA correlated with all parameters but CRP". Please rephrase.
4- The sentence is not clear "Oxygen saturation at admission to the hospital was negatively
related with all of parameters but FIB-4". Please rephrase.
6- In Discussion section, reference 26 [e.g. 26] ……….please omit "e.g".
Title: Intriguing findings of liver fibrosis following Covid-19
Version: 1 Date: 10 Jun 2021
Reviewer's report:
This study tackles an important issue related to COVID-19 which assess liver fibrosis in
COVID-19 patients by serum HA and FIB-4 and to detect their relationship with liver function
tests, inflammatory markers, and blood oxygen saturation irrespective to underlying liver
disease.
My comments are.
1- In abstract section, there is a contradictory between P-value mentioned in sentence" HA
was higher in patients with higher liver stiffness (rs=0.30, p<0.05)" and in the sentence" SWE
correlated with HA (rs=0.30, p=0.021)". Please revise.
2- In introduction section, reference 5 [e.g. 5] ……….please omit "e.g".
3- In method section, the abbreviation of (RT-PCT) in the sentence "diagnosis of SARS-CoV-2
infection………."  Please correct to "RT-PCR".
4- Mention the unit of each parameter of FIB-4 equation.
5- In result section.
1- Author mentioned HA correlated with AST (rs=0.60, p<0.001) but r = 0.52 in the table 2
please revise.
2- Author mentioned HA correlated with FIB-4 (r=0.27) but r = 0.5 in the table 2 please revise.
3-  The sentence is not clear "HA correlated with all parameters but CRP". Please rephrase.
4- The sentence is not clear "Oxygen saturation at admission to the hospital was negatively
related with all of parameters but FIB-4". Please rephrase.
6- In Discussion section, reference 26 [e.g. 26] ……….please omit "e.g".
Please review this paper.
user
Title: Intriguing findings of liver fibrosis following Covid-19
Version: 1 Date: 10 Jun 2021
Reviewer's report:
This study tackles an important issue related to COVID-19 which assess liver fibrosis in
COVID-19 patients by serum HA and FIB-4 and to detect their relationship with liver function
tests, inflammatory markers, and blood oxygen saturation irrespective to underlying liver
disease.
My comments are.
1- In abstract section, there is a contradictory between P-value mentioned in sentence" HA
was higher in patients with higher liver stiffness (rs=0.30, p<0.05)" and in the sentence" SWE
correlated with HA (rs=0.30, p=0.021)". Please revise.
2- In introduction section, reference 5 [e.g. 5] ……….please omit "e.g".
3- In method section, the abbreviation of (RT-PCT) in the sentence "diagnosis of SARS-CoV-2
infection………."  Please correct to "RT-PCR".
4- Mention the unit of each parameter of FIB-4 equation.
5- In result section.
1- Author mentioned HA correlated with AST (rs=0.60, p<0.001) but r = 0.52 in the table 2
please revise.
2- Author mentioned HA correlated with FIB-4 (r=0.27) but r = 0.5 in the table 2 please revise.
3-  The sentence is not clear "HA correlated with all parameters but CRP". Please rephrase.
4- The sentence is not clear "Oxygen saturation at admission to the hospital was negatively
related with all of parameters but FIB-4". Please rephrase.
6- In Discussion section, reference 26 [e.g. 26] ……….please omit "e.g".
assistant