Reviewer's report
Title:Carbon monoxide-Releasing Molecule-2 (CORM-2) attenuates acute
hepatic ischemia reperfusion injury in rats
Version: 1Date:7 January 2010
Reviewer: Leandra Ramalho
Reviewer's report:
Reviewer(s)' Comments to Author:
The present study determined the effect of Carbon monoxide-Releasing
Molecule-2 (CORM-2) in the acute hepatic ischemia reperfusion injury in rats.
The animals underwent to a classical ischemia/reperfusion model and the
respective treatments. The authors have accessed frequently utilized parameters
in ischemia/reperfusion studies. The authors conclude that CORM-2 ameliorates
acute hepatic ischemia reperfusion injury in rats.
Minor comments:
1. The authors should provide an alternative method, like as PCR, to confirm the
immunochemistry findings.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
'I declare that I have no competing interests'
Reviewer's report
Title:Carbon monoxide-Releasing Molecule-2 (CORM-2) attenuates acute
hepatic ischemia reperfusion injury in rats
Version: 1Date:7 January 2010
Reviewer: Leandra Ramalho
Reviewer's report:
Reviewer(s)' Comments to Author:
The present study determined the effect of Carbon monoxide-Releasing
Molecule-2 (CORM-2) in the acute hepatic ischemia reperfusion injury in rats.
The animals underwent to a classical ischemia/reperfusion model and the
respective treatments. The authors have accessed frequently utilized parameters
in ischemia/reperfusion studies. The authors conclude that CORM-2 ameliorates
acute hepatic ischemia reperfusion injury in rats.
Minor comments:
1. The authors should provide an alternative method, like as PCR, to confirm the
immunochemistry findings.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
'I declare that I have no competing interests'
Please review this paper.
user
Reviewer's report
Title:Carbon monoxide-Releasing Molecule-2 (CORM-2) attenuates acute
hepatic ischemia reperfusion injury in rats
Version: 1Date:7 January 2010
Reviewer: Leandra Ramalho
Reviewer's report:
Reviewer(s)' Comments to Author:
The present study determined the effect of Carbon monoxide-Releasing
Molecule-2 (CORM-2) in the acute hepatic ischemia reperfusion injury in rats.
The animals underwent to a classical ischemia/reperfusion model and the
respective treatments. The authors have accessed frequently utilized parameters
in ischemia/reperfusion studies. The authors conclude that CORM-2 ameliorates
acute hepatic ischemia reperfusion injury in rats.
Minor comments:
1. The authors should provide an alternative method, like as PCR, to confirm the
immunochemistry findings.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
'I declare that I have no competing interests'
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