Reviewer's report
Title:Prevalence of Non-Alcoholic Fatty Pancreas Disease (NAFPD) and Its Risk
Factors among Adult Medical Check-Up Patients in a Private Hospital: A Large
Cross Sectional Study
Version:4Date:2 November 2015
Reviewer: Gabor Firneisz
Reviewer's report:
I still suggest to correct the following 2 sentences on page 9 Line 209-210 in the
final text as a minor correction:
“The beta cell dysfunction will cause insulin resistance condition. Long-term
hyperglycemia condition will also cause beta cell dysfunction due to
hyperinsulinemia.” (?)
due to that Beta cell dysfunction is rather a medical expression that is used to
describe the reduced relative capacity of beta cells to secrete insulin compared
to as it would be needed to maintain optimal glycemic control.
Therefore I suggest to replace these two sentences in the final text with a
sentence reflecting a better understanding of beta cell dysfunction, similarly to
e.g. as follows:
'The beta cell dsyfunction results in an unmet relative insulin need to maintain
optimal glycemic control and in combination with insulin resistance at the
periphery synergistically contributes to the long-term hyperglycemia.'
Otherwise all the requested changes were made with satisfaction.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: Yes, but I do not feel adequately qualified to assess the
statistics.
Reviewer's report
Title:Prevalence of Non-Alcoholic Fatty Pancreas Disease (NAFPD) and Its Risk
Factors among Adult Medical Check-Up Patients in a Private Hospital: A Large
Cross Sectional Study
Version:4Date:2 November 2015
Reviewer: Gabor Firneisz
Reviewer's report:
I still suggest to correct the following 2 sentences on page 9 Line 209-210 in the
final text as a minor correction:
“The beta cell dysfunction will cause insulin resistance condition. Long-term
hyperglycemia condition will also cause beta cell dysfunction due to
hyperinsulinemia.” (?)
due to that Beta cell dysfunction is rather a medical expression that is used to
describe the reduced relative capacity of beta cells to secrete insulin compared
to as it would be needed to maintain optimal glycemic control.
Therefore I suggest to replace these two sentences in the final text with a
sentence reflecting a better understanding of beta cell dysfunction, similarly to
e.g. as follows:
'The beta cell dsyfunction results in an unmet relative insulin need to maintain
optimal glycemic control and in combination with insulin resistance at the
periphery synergistically contributes to the long-term hyperglycemia.'
Otherwise all the requested changes were made with satisfaction.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: Yes, but I do not feel adequately qualified to assess the
statistics.
Please review this paper.
user
Reviewer's report
Title:Prevalence of Non-Alcoholic Fatty Pancreas Disease (NAFPD) and Its Risk
Factors among Adult Medical Check-Up Patients in a Private Hospital: A Large
Cross Sectional Study
Version:4Date:2 November 2015
Reviewer: Gabor Firneisz
Reviewer's report:
I still suggest to correct the following 2 sentences on page 9 Line 209-210 in the
final text as a minor correction:
“The beta cell dysfunction will cause insulin resistance condition. Long-term
hyperglycemia condition will also cause beta cell dysfunction due to
hyperinsulinemia.” (?)
due to that Beta cell dysfunction is rather a medical expression that is used to
describe the reduced relative capacity of beta cells to secrete insulin compared
to as it would be needed to maintain optimal glycemic control.
Therefore I suggest to replace these two sentences in the final text with a
sentence reflecting a better understanding of beta cell dysfunction, similarly to
e.g. as follows:
'The beta cell dsyfunction results in an unmet relative insulin need to maintain
optimal glycemic control and in combination with insulin resistance at the
periphery synergistically contributes to the long-term hyperglycemia.'
Otherwise all the requested changes were made with satisfaction.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: Yes, but I do not feel adequately qualified to assess the
statistics.
assistant