Reviewer's report
Title:Inflammatory myoglandular polyp of the cecum: case report and review of
literature
Version: 2Date:22 December 2009
Reviewer: gabriel becheanu
Reviewer's report:
Major Compulsory Revisions
None
Minor Essential Revisions
None
Discretionary Revisions
The histological and immnunohistological pictures (figure 3, a - d) are not
convincing (in my opinion) for the positive histological diagnosis of an
inflammatory myoglandular polyp: the muscular hyperplasia is not prominent (anti
- actin reaction reveals very well the walls of the vessels, but few muscular
fibers), as well as glandular hyperplasia; only cystic dilatations of the glands are
obvious. Around the glands (dilated or not) there is no obvious muscular
hyperplasia.
In the same time, there is too much inflammation, diffuse, with granulation tissue,
superficial and profound.
Again, in my opinion, these figures are more consistent for the diagnosis of an
inflammatory polyp versus juvenile polyp.
Some other pictures in the literature are not concludent for the diagnosis of
IMGP.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests.
Reviewer's report
Title:Inflammatory myoglandular polyp of the cecum: case report and review of
literature
Version: 2Date:22 December 2009
Reviewer: gabriel becheanu
Reviewer's report:
Major Compulsory Revisions
None
Minor Essential Revisions
None
Discretionary Revisions
The histological and immnunohistological pictures (figure 3, a - d) are not
convincing (in my opinion) for the positive histological diagnosis of an
inflammatory myoglandular polyp: the muscular hyperplasia is not prominent (anti
- actin reaction reveals very well the walls of the vessels, but few muscular
fibers), as well as glandular hyperplasia; only cystic dilatations of the glands are
obvious. Around the glands (dilated or not) there is no obvious muscular
hyperplasia.
In the same time, there is too much inflammation, diffuse, with granulation tissue,
superficial and profound.
Again, in my opinion, these figures are more consistent for the diagnosis of an
inflammatory polyp versus juvenile polyp.
Some other pictures in the literature are not concludent for the diagnosis of
IMGP.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests.
Please review this paper.
user
Reviewer's report
Title:Inflammatory myoglandular polyp of the cecum: case report and review of
literature
Version: 2Date:22 December 2009
Reviewer: gabriel becheanu
Reviewer's report:
Major Compulsory Revisions
None
Minor Essential Revisions
None
Discretionary Revisions
The histological and immnunohistological pictures (figure 3, a - d) are not
convincing (in my opinion) for the positive histological diagnosis of an
inflammatory myoglandular polyp: the muscular hyperplasia is not prominent (anti
- actin reaction reveals very well the walls of the vessels, but few muscular
fibers), as well as glandular hyperplasia; only cystic dilatations of the glands are
obvious. Around the glands (dilated or not) there is no obvious muscular
hyperplasia.
In the same time, there is too much inflammation, diffuse, with granulation tissue,
superficial and profound.
Again, in my opinion, these figures are more consistent for the diagnosis of an
inflammatory polyp versus juvenile polyp.
Some other pictures in the literature are not concludent for the diagnosis of
IMGP.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests.
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