Title: Growth development of children and adolescents with inflammatory bowel disease in the
period 2000-2014 based on data of the Saxon Pediatric IBD Registry: A population-based study
Version: 0 Date: 08 Oct 2023
Reviewer's report:
PEER REVIEWER ASSESSMENTS:
OBJECTIVE - Full research articles: is there a clear objective that addresses a testable research
question(s) (brief or other article types: is there a clear objective)?
Yes - there is a clear objective
DESIGN - Is the current approach (including controls and analysis protocols) appropriate for
the objective?
Yes - the approach is appropriate
EXECUTION - Are the experiments and analyses performed with technical rigor to allow
confidence in the results?
Yes - experiments and analyses were performed appropriately
STATISTICS - Is the use of statistics in the manuscript appropriate?
Yes - appropriate statistical analyses have been used in the study
INTERPRETATION - Is the current interpretation/discussion of the results reasonable and not
overstated?
No - there are minor issues
OVERALL MANUSCRIPT POTENTIAL - Is the current version of this work technically
sound? If not, can revisions be made to make the work technically sound?
Probably - with minor revisions
PEER REVIEWER COMMENTS:
GENERAL COMMENTS: Thank you for allowing me to review this interesting and well written
study.
1. Are the authors able to assess the impact of different treatment (biologics vs non-biologics),
disease duration, disease severity and extent on the weight and height of these children?
2. Are the authors able to demonstrate if early onset IBD is associated with more abnormal height
and weight compared to disease that happens late?
REQUESTED REVISIONS:
Please see the comments above.
ADDITIONAL REQUESTS/SUGGESTIONS:
Please see above
Title: Growth development of children and adolescents with inflammatory bowel disease in the
period 2000-2014 based on data of the Saxon Pediatric IBD Registry: A population-based study
Version: 0 Date: 08 Oct 2023
Reviewer's report:
PEER REVIEWER ASSESSMENTS:
OBJECTIVE - Full research articles: is there a clear objective that addresses a testable research
question(s) (brief or other article types: is there a clear objective)?
Yes - there is a clear objective
DESIGN - Is the current approach (including controls and analysis protocols) appropriate for
the objective?
Yes - the approach is appropriate
EXECUTION - Are the experiments and analyses performed with technical rigor to allow
confidence in the results?
Yes - experiments and analyses were performed appropriately
STATISTICS - Is the use of statistics in the manuscript appropriate?
Yes - appropriate statistical analyses have been used in the study
INTERPRETATION - Is the current interpretation/discussion of the results reasonable and not
overstated?
No - there are minor issues
OVERALL MANUSCRIPT POTENTIAL - Is the current version of this work technically
sound? If not, can revisions be made to make the work technically sound?
Probably - with minor revisions
PEER REVIEWER COMMENTS:
GENERAL COMMENTS: Thank you for allowing me to review this interesting and well written
study.
1. Are the authors able to assess the impact of different treatment (biologics vs non-biologics),
disease duration, disease severity and extent on the weight and height of these children?
2. Are the authors able to demonstrate if early onset IBD is associated with more abnormal height
and weight compared to disease that happens late?
REQUESTED REVISIONS:
Please see the comments above.
ADDITIONAL REQUESTS/SUGGESTIONS:
Please see above
Please review this paper.
user
Title: Growth development of children and adolescents with inflammatory bowel disease in the
period 2000-2014 based on data of the Saxon Pediatric IBD Registry: A population-based study
Version: 0 Date: 08 Oct 2023
Reviewer's report:
PEER REVIEWER ASSESSMENTS:
OBJECTIVE - Full research articles: is there a clear objective that addresses a testable research
question(s) (brief or other article types: is there a clear objective)?
Yes - there is a clear objective
DESIGN - Is the current approach (including controls and analysis protocols) appropriate for
the objective?
Yes - the approach is appropriate
EXECUTION - Are the experiments and analyses performed with technical rigor to allow
confidence in the results?
Yes - experiments and analyses were performed appropriately
STATISTICS - Is the use of statistics in the manuscript appropriate?
Yes - appropriate statistical analyses have been used in the study
INTERPRETATION - Is the current interpretation/discussion of the results reasonable and not
overstated?
No - there are minor issues
OVERALL MANUSCRIPT POTENTIAL - Is the current version of this work technically
sound? If not, can revisions be made to make the work technically sound?
Probably - with minor revisions
PEER REVIEWER COMMENTS:
GENERAL COMMENTS: Thank you for allowing me to review this interesting and well written
study.
1. Are the authors able to assess the impact of different treatment (biologics vs non-biologics),
disease duration, disease severity and extent on the weight and height of these children?
2. Are the authors able to demonstrate if early onset IBD is associated with more abnormal height
and weight compared to disease that happens late?
REQUESTED REVISIONS:
Please see the comments above.
ADDITIONAL REQUESTS/SUGGESTIONS:
Please see above
assistant