Reviewer's report
Title:Scintigraphic evaluation of oesophageal motility during adjuvant
radiotherapy to the mediastinum
Version: 1Date:4 June 2008
Reviewer: Roberto O Dantas
Reviewer's report:
Major revisions.
This paper need some revisions:
1.The scintigraphic method measure transit and not motility. In the conclusion
present in the abstract the reference is about "oesophageal transit". The did not
see abnormal peristaltic response.
2. What is the unit of ER40? In table 3 and text there were no units of ER40s and
of MTT.
3. The dysphagia and odynophagia of the patients may be consequence of
motility alterations but also of mucosa sensitivity. This possibility should be
present in discussion.
4. Why use three phases during the scintigraphic examination? What is the utility
of the last phase?
5. What was the scoring method of the scintigraphic examination?
6. What are the explanations for results that showed more residues in upright
position than in supine position, more residues with liquid bolus than semi-solids
bolus?
7. The numbers showee in results ar very close to each other. Althoug there are
differences between T2 and T0 it is small. The unit of residuess (counts or
%)should be in the text.
Minor revisions
1. It is better to wright 40 seconds than 40".
2. There is 3 figures legends in the text, but the number of figures is 5. There is
no legend for figures 4 and 5.
3. IT is important to have the units of measurements.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interest.
Reviewer's report
Title:Scintigraphic evaluation of oesophageal motility during adjuvant
radiotherapy to the mediastinum
Version: 1Date:4 June 2008
Reviewer: Roberto O Dantas
Reviewer's report:
Major revisions.
This paper need some revisions:
1.The scintigraphic method measure transit and not motility. In the conclusion
present in the abstract the reference is about "oesophageal transit". The did not
see abnormal peristaltic response.
2. What is the unit of ER40? In table 3 and text there were no units of ER40s and
of MTT.
3. The dysphagia and odynophagia of the patients may be consequence of
motility alterations but also of mucosa sensitivity. This possibility should be
present in discussion.
4. Why use three phases during the scintigraphic examination? What is the utility
of the last phase?
5. What was the scoring method of the scintigraphic examination?
6. What are the explanations for results that showed more residues in upright
position than in supine position, more residues with liquid bolus than semi-solids
bolus?
7. The numbers showee in results ar very close to each other. Althoug there are
differences between T2 and T0 it is small. The unit of residuess (counts or
%)should be in the text.
Minor revisions
1. It is better to wright 40 seconds than 40".
2. There is 3 figures legends in the text, but the number of figures is 5. There is
no legend for figures 4 and 5.
3. IT is important to have the units of measurements.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interest.
Please review this paper.
user
Reviewer's report
Title:Scintigraphic evaluation of oesophageal motility during adjuvant
radiotherapy to the mediastinum
Version: 1Date:4 June 2008
Reviewer: Roberto O Dantas
Reviewer's report:
Major revisions.
This paper need some revisions:
1.The scintigraphic method measure transit and not motility. In the conclusion
present in the abstract the reference is about "oesophageal transit". The did not
see abnormal peristaltic response.
2. What is the unit of ER40? In table 3 and text there were no units of ER40s and
of MTT.
3. The dysphagia and odynophagia of the patients may be consequence of
motility alterations but also of mucosa sensitivity. This possibility should be
present in discussion.
4. Why use three phases during the scintigraphic examination? What is the utility
of the last phase?
5. What was the scoring method of the scintigraphic examination?
6. What are the explanations for results that showed more residues in upright
position than in supine position, more residues with liquid bolus than semi-solids
bolus?
7. The numbers showee in results ar very close to each other. Althoug there are
differences between T2 and T0 it is small. The unit of residuess (counts or
%)should be in the text.
Minor revisions
1. It is better to wright 40 seconds than 40".
2. There is 3 figures legends in the text, but the number of figures is 5. There is
no legend for figures 4 and 5.
3. IT is important to have the units of measurements.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interest.
assistant