Title: TITLE: The Association Between Blood Pressure and Gallstones and the Age of First
Cholecystectomy in U.S. Adults: Results from a Cross-Sectional Study
Version: 3 Date: 01 Jan 2025
Reviewer:  Yüksel Do#an
Reviewer's report:
The revised manuscript is of good quality in terms of clarity, logic and adherence to scientific
rules. Significant improvements with respect to earlier drafts can be seen in the presentation of
the results and the strengthening of the statistical analysis. However, the primary focus appears
to be on extending the analysis and increasing the depth of the narrative, as no specific statements
were identified regarding the correction of previous data.
1.Consistency of abbreviations: The use of 'GD' (gallstone disease) has been standardised;
occasionally 'GDS' is used incorrectly.
2.Original: "Effective blood pressure control not only improves cardiovascular outcomes, but
also reduces the risk of GD or delays in gallbladder-related procedures."
Proposed: "Effective blood pressure control improves cardiovascular outcomes and reduces the
risk of GD or delays in gallbladder-related procedures."
3.For accuracy, replace "poses significant risks" with "carries significant risks" in the the
INTRODUCTION for accuracy.
4.Unnecessary statements: Eliminate redundancies such as "further investigation of the
underlying mechanisms" (already implied by "future longitudinal studies").
5.Correct "reduce complications" in DISCUSSION to "reduce complications".
These corrections will further improve the clarity and readability of the article.
‘’This study identified an association between modifiable risk factors, particularly BP, and GD
in individuals aged > 48 years, as well as the age at first cholecystectomy’’. EVEN IF THE
ARTICLE WAS WRITTEN CAREFULLY, I THINK THERE IS NOT ENOUGH DATA TO
REACH THE FINAL CONCLUSION. FUTURE STUDIES NEED TO SUPPORT THIS. .
Title: TITLE: The Association Between Blood Pressure and Gallstones and the Age of First
Cholecystectomy in U.S. Adults: Results from a Cross-Sectional Study
Version: 3 Date: 01 Jan 2025
Reviewer:  Yüksel Do#an
Reviewer's report:
The revised manuscript is of good quality in terms of clarity, logic and adherence to scientific
rules. Significant improvements with respect to earlier drafts can be seen in the presentation of
the results and the strengthening of the statistical analysis. However, the primary focus appears
to be on extending the analysis and increasing the depth of the narrative, as no specific statements
were identified regarding the correction of previous data.
1.Consistency of abbreviations: The use of 'GD' (gallstone disease) has been standardised;
occasionally 'GDS' is used incorrectly.
2.Original: "Effective blood pressure control not only improves cardiovascular outcomes, but
also reduces the risk of GD or delays in gallbladder-related procedures."
Proposed: "Effective blood pressure control improves cardiovascular outcomes and reduces the
risk of GD or delays in gallbladder-related procedures."
3.For accuracy, replace "poses significant risks" with "carries significant risks" in the the
INTRODUCTION for accuracy.
4.Unnecessary statements: Eliminate redundancies such as "further investigation of the
underlying mechanisms" (already implied by "future longitudinal studies").
5.Correct "reduce complications" in DISCUSSION to "reduce complications".
These corrections will further improve the clarity and readability of the article.
‘’This study identified an association between modifiable risk factors, particularly BP, and GD
in individuals aged > 48 years, as well as the age at first cholecystectomy’’. EVEN IF THE
ARTICLE WAS WRITTEN CAREFULLY, I THINK THERE IS NOT ENOUGH DATA TO
REACH THE FINAL CONCLUSION. FUTURE STUDIES NEED TO SUPPORT THIS. .
Please review this paper.
user
Title: TITLE: The Association Between Blood Pressure and Gallstones and the Age of First
Cholecystectomy in U.S. Adults: Results from a Cross-Sectional Study
Version: 3 Date: 01 Jan 2025
Reviewer:  Yüksel Do#an
Reviewer's report:
The revised manuscript is of good quality in terms of clarity, logic and adherence to scientific
rules. Significant improvements with respect to earlier drafts can be seen in the presentation of
the results and the strengthening of the statistical analysis. However, the primary focus appears
to be on extending the analysis and increasing the depth of the narrative, as no specific statements
were identified regarding the correction of previous data.
1.Consistency of abbreviations: The use of 'GD' (gallstone disease) has been standardised;
occasionally 'GDS' is used incorrectly.
2.Original: "Effective blood pressure control not only improves cardiovascular outcomes, but
also reduces the risk of GD or delays in gallbladder-related procedures."
Proposed: "Effective blood pressure control improves cardiovascular outcomes and reduces the
risk of GD or delays in gallbladder-related procedures."
3.For accuracy, replace "poses significant risks" with "carries significant risks" in the the
INTRODUCTION for accuracy.
4.Unnecessary statements: Eliminate redundancies such as "further investigation of the
underlying mechanisms" (already implied by "future longitudinal studies").
5.Correct "reduce complications" in DISCUSSION to "reduce complications".
These corrections will further improve the clarity and readability of the article.
‘’This study identified an association between modifiable risk factors, particularly BP, and GD
in individuals aged > 48 years, as well as the age at first cholecystectomy’’. EVEN IF THE
ARTICLE WAS WRITTEN CAREFULLY, I THINK THERE IS NOT ENOUGH DATA TO
REACH THE FINAL CONCLUSION. FUTURE STUDIES NEED TO SUPPORT THIS. .
assistant