Reviewer's report
Title:Clinical relevance of the cagA, tnpA and tnpB genes in Helicobacter pylori
Version: 1Date:23 September 2013
Reviewer: Francesco Franceschi
Reviewer's report:
This is a study aimed at investigating on the role of CagA, tnpA and tnpB in
patients with gastric cancer. While the idea, even though not properly new, may
be of interest, my only concern is on the enrolled population. In fact, the authors
have enrolled 360 patients and the prevalence of either peptic ulcer or gastric
cancer was very high. Therefore, the authors need to explain what is the
prevalence of peptic culcer and gastric cancer in that population or whether they
enrolled patients based on the disease instead of on the symptoms.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I have no competing interests
Reviewer's report
Title:Clinical relevance of the cagA, tnpA and tnpB genes in Helicobacter pylori
Version: 1Date:23 September 2013
Reviewer: Francesco Franceschi
Reviewer's report:
This is a study aimed at investigating on the role of CagA, tnpA and tnpB in
patients with gastric cancer. While the idea, even though not properly new, may
be of interest, my only concern is on the enrolled population. In fact, the authors
have enrolled 360 patients and the prevalence of either peptic ulcer or gastric
cancer was very high. Therefore, the authors need to explain what is the
prevalence of peptic culcer and gastric cancer in that population or whether they
enrolled patients based on the disease instead of on the symptoms.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I have no competing interests
Please review this paper.
user
Reviewer's report
Title:Clinical relevance of the cagA, tnpA and tnpB genes in Helicobacter pylori
Version: 1Date:23 September 2013
Reviewer: Francesco Franceschi
Reviewer's report:
This is a study aimed at investigating on the role of CagA, tnpA and tnpB in
patients with gastric cancer. While the idea, even though not properly new, may
be of interest, my only concern is on the enrolled population. In fact, the authors
have enrolled 360 patients and the prevalence of either peptic ulcer or gastric
cancer was very high. Therefore, the authors need to explain what is the
prevalence of peptic culcer and gastric cancer in that population or whether they
enrolled patients based on the disease instead of on the symptoms.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I have no competing interests
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