Title: Diagnostic Yield of Bidirectional Endoscopy for Iron Deficiency Anemia in Young
Patients
Version: 1 Date: 20 Jun 2024
Reviewer's report:
The authors aimed to investigate the diagnostic yield of bidirectional endoscopy in men younger
than age 45 and premenopausal women.
Main Comment:
- The study is retrospective in nature, and despite being done over a 14-year period, only a small
number of patients were included.
Other comments:
- For men with IDA, endoscopic evaluation is recommended by current guidelines and there is
no age threshold of 45 stated by authors.
-    Please describe how patients were selected for this study. Did you search in the procedure
indication?
-    The authors mentioned that they aimed to look at the diagnostic yield for pre-menopausal
women. However, women were included based on their age, not menopausal status.
- For classification of endoscopic findings in patients with pathology proven gastritis, please
mention whether gastric pathology was seen endoscopically or not.
- While the title indicates the yield of bi-directional endoscopy, authors included 20 patients
who did not have bidirectional endoscopy.
- Authors should mention how patients were selected for biopsy, and total number of patients
who had biopsies taken.
- The abstract needs to be more concise, and conclusion should include main study finding
according to main study aim and avoid speculation.
- Please provide some details about symptoms.
- Please include section about statistical analysis
Title: Diagnostic Yield of Bidirectional Endoscopy for Iron Deficiency Anemia in Young
Patients
Version: 1 Date: 20 Jun 2024
Reviewer's report:
The authors aimed to investigate the diagnostic yield of bidirectional endoscopy in men younger
than age 45 and premenopausal women.
Main Comment:
- The study is retrospective in nature, and despite being done over a 14-year period, only a small
number of patients were included.
Other comments:
- For men with IDA, endoscopic evaluation is recommended by current guidelines and there is
no age threshold of 45 stated by authors.
-    Please describe how patients were selected for this study. Did you search in the procedure
indication?
-    The authors mentioned that they aimed to look at the diagnostic yield for pre-menopausal
women. However, women were included based on their age, not menopausal status.
- For classification of endoscopic findings in patients with pathology proven gastritis, please
mention whether gastric pathology was seen endoscopically or not.
- While the title indicates the yield of bi-directional endoscopy, authors included 20 patients
who did not have bidirectional endoscopy.
- Authors should mention how patients were selected for biopsy, and total number of patients
who had biopsies taken.
- The abstract needs to be more concise, and conclusion should include main study finding
according to main study aim and avoid speculation.
- Please provide some details about symptoms.
- Please include section about statistical analysis
Please review this paper.
user
Title: Diagnostic Yield of Bidirectional Endoscopy for Iron Deficiency Anemia in Young
Patients
Version: 1 Date: 20 Jun 2024
Reviewer's report:
The authors aimed to investigate the diagnostic yield of bidirectional endoscopy in men younger
than age 45 and premenopausal women.
Main Comment:
- The study is retrospective in nature, and despite being done over a 14-year period, only a small
number of patients were included.
Other comments:
- For men with IDA, endoscopic evaluation is recommended by current guidelines and there is
no age threshold of 45 stated by authors.
-    Please describe how patients were selected for this study. Did you search in the procedure
indication?
-    The authors mentioned that they aimed to look at the diagnostic yield for pre-menopausal
women. However, women were included based on their age, not menopausal status.
- For classification of endoscopic findings in patients with pathology proven gastritis, please
mention whether gastric pathology was seen endoscopically or not.
- While the title indicates the yield of bi-directional endoscopy, authors included 20 patients
who did not have bidirectional endoscopy.
- Authors should mention how patients were selected for biopsy, and total number of patients
who had biopsies taken.
- The abstract needs to be more concise, and conclusion should include main study finding
according to main study aim and avoid speculation.
- Please provide some details about symptoms.
- Please include section about statistical analysis
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