Title: Three-to-Six Month Post-POEM Timed Barium Esophagram Can Predict Esophageal
Contents and May Stratify Aspiration Risk on Follow-up EGD
Version: 2 Date: 03 Mar 2025
Reviewer's report:
Thank you for giving me the opportunity to review this paper.
This study examines whether esophagram findings before endoscopy can predict the presence
of esophageal contents three months after POEM, aiming to ensure the safe performance of
endoscopy. I believe this provides clinically valuable information.
Comments:
• Regarding Table 1:
It would be clearer to present patient background factors in one table and the outcomes
comparing pre- and post-POEM in a separate table.
• Regarding the ROC curve:
While the study sets 7 cm of the barium column as the cutoff value for residual esophageal
contents based on the ROC curve, the actual median barium column height after POEM is 0
cm. It would be beneficial to include interquartile range (IQR) data to provide a more detailed
distribution of the results.
• Regarding the indication for endotracheal intubation during endoscopy:
In Japan, endotracheal intubation is not performed during endoscopy. What criteria are used to
determine the need for endotracheal intubation?
Title: Three-to-Six Month Post-POEM Timed Barium Esophagram Can Predict Esophageal
Contents and May Stratify Aspiration Risk on Follow-up EGD
Version: 2 Date: 03 Mar 2025
Reviewer's report:
Thank you for giving me the opportunity to review this paper.
This study examines whether esophagram findings before endoscopy can predict the presence
of esophageal contents three months after POEM, aiming to ensure the safe performance of
endoscopy. I believe this provides clinically valuable information.
Comments:
• Regarding Table 1:
It would be clearer to present patient background factors in one table and the outcomes
comparing pre- and post-POEM in a separate table.
• Regarding the ROC curve:
While the study sets 7 cm of the barium column as the cutoff value for residual esophageal
contents based on the ROC curve, the actual median barium column height after POEM is 0
cm. It would be beneficial to include interquartile range (IQR) data to provide a more detailed
distribution of the results.
• Regarding the indication for endotracheal intubation during endoscopy:
In Japan, endotracheal intubation is not performed during endoscopy. What criteria are used to
determine the need for endotracheal intubation?
Please review this paper.
user
Title: Three-to-Six Month Post-POEM Timed Barium Esophagram Can Predict Esophageal
Contents and May Stratify Aspiration Risk on Follow-up EGD
Version: 2 Date: 03 Mar 2025
Reviewer's report:
Thank you for giving me the opportunity to review this paper.
This study examines whether esophagram findings before endoscopy can predict the presence
of esophageal contents three months after POEM, aiming to ensure the safe performance of
endoscopy. I believe this provides clinically valuable information.
Comments:
• Regarding Table 1:
It would be clearer to present patient background factors in one table and the outcomes
comparing pre- and post-POEM in a separate table.
• Regarding the ROC curve:
While the study sets 7 cm of the barium column as the cutoff value for residual esophageal
contents based on the ROC curve, the actual median barium column height after POEM is 0
cm. It would be beneficial to include interquartile range (IQR) data to provide a more detailed
distribution of the results.
• Regarding the indication for endotracheal intubation during endoscopy:
In Japan, endotracheal intubation is not performed during endoscopy. What criteria are used to
determine the need for endotracheal intubation?
assistant