Title: The Association between Non- and Pro-Healthy Diet Indices and the Risk of Colorectal
Cancer: A Case-Control Study
Version: 1 Date: 17 Oct 2024
Reviewer:  Panagiotis Tsibouris
Reviewer's report:
Effect of risk factors in Ca bowel starts several year before diagnosis Moreover symptoms during
the symptomatic fase could lead in adaptation of nutricional habits Thus it is important to know
when questionnaire was given In addition several snapshots are advisable Abstract should define
when questionnaire was given Methods Controls should had had a colonoscopy performed to
exclude large adenomas usually faced as advance neoplasia in most studies At least one year
of follow-up could exclude cancer in controls  Authors should define if other exclusion criteria
were taken into consideration like underlined comorbidities or pregnancy How family history
was defined? How authors have overcame recalling biases about dietary habits several years ago
Statistics Study sample calculation should be provided
Title: The Association between Non- and Pro-Healthy Diet Indices and the Risk of Colorectal
Cancer: A Case-Control Study
Version: 1 Date: 17 Oct 2024
Reviewer:  Panagiotis Tsibouris
Reviewer's report:
Effect of risk factors in Ca bowel starts several year before diagnosis Moreover symptoms during
the symptomatic fase could lead in adaptation of nutricional habits Thus it is important to know
when questionnaire was given In addition several snapshots are advisable Abstract should define
when questionnaire was given Methods Controls should had had a colonoscopy performed to
exclude large adenomas usually faced as advance neoplasia in most studies At least one year
of follow-up could exclude cancer in controls  Authors should define if other exclusion criteria
were taken into consideration like underlined comorbidities or pregnancy How family history
was defined? How authors have overcame recalling biases about dietary habits several years ago
Statistics Study sample calculation should be provided
Please review this paper.
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Title: The Association between Non- and Pro-Healthy Diet Indices and the Risk of Colorectal
Cancer: A Case-Control Study
Version: 1 Date: 17 Oct 2024
Reviewer:  Panagiotis Tsibouris
Reviewer's report:
Effect of risk factors in Ca bowel starts several year before diagnosis Moreover symptoms during
the symptomatic fase could lead in adaptation of nutricional habits Thus it is important to know
when questionnaire was given In addition several snapshots are advisable Abstract should define
when questionnaire was given Methods Controls should had had a colonoscopy performed to
exclude large adenomas usually faced as advance neoplasia in most studies At least one year
of follow-up could exclude cancer in controls  Authors should define if other exclusion criteria
were taken into consideration like underlined comorbidities or pregnancy How family history
was defined? How authors have overcame recalling biases about dietary habits several years ago
Statistics Study sample calculation should be provided
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