Reviewer's report
Title:Fingertip rapid point-of-care test in adult case-finding in coeliac disease
Version: 2Date:15 April 2013
Reviewer: fabiana zingone
Reviewer's report:
1. The authors should provide further details on the previous studies which had
tested the same diagnostic procedure in the introduction. They should also
compare their results to the ones reported in the discussion.
2. What is the time of the recruitment?
3. The study population should be better defined:
- The authors report in the title and several times in the text that they considered
adult subjects; however, the range of age reported is 1.2-77 years.
- Inclusion and exclusion criteria are not reported.
- The study population baseline data (i.e BMI, sex, comorbidities and
autoimmune diseases) are not reported.
4. Could the authors report the sensitivity and specificity of the test?
5. The authors checked small bowel antibody deposits but they do not report any
interpretation of the findings. Is this test useful for this particular study?
Minor comments: in the first paragraphs of the result please change
(case 5 in Table 1) with (case 4 in Table 1)
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Reviewer's report
Title:Fingertip rapid point-of-care test in adult case-finding in coeliac disease
Version: 2Date:15 April 2013
Reviewer: fabiana zingone
Reviewer's report:
1. The authors should provide further details on the previous studies which had
tested the same diagnostic procedure in the introduction. They should also
compare their results to the ones reported in the discussion.
2. What is the time of the recruitment?
3. The study population should be better defined:
- The authors report in the title and several times in the text that they considered
adult subjects; however, the range of age reported is 1.2-77 years.
- Inclusion and exclusion criteria are not reported.
- The study population baseline data (i.e BMI, sex, comorbidities and
autoimmune diseases) are not reported.
4. Could the authors report the sensitivity and specificity of the test?
5. The authors checked small bowel antibody deposits but they do not report any
interpretation of the findings. Is this test useful for this particular study?
Minor comments: in the first paragraphs of the result please change
(case 5 in Table 1) with (case 4 in Table 1)
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Please review this paper.
user
Reviewer's report
Title:Fingertip rapid point-of-care test in adult case-finding in coeliac disease
Version: 2Date:15 April 2013
Reviewer: fabiana zingone
Reviewer's report:
1. The authors should provide further details on the previous studies which had
tested the same diagnostic procedure in the introduction. They should also
compare their results to the ones reported in the discussion.
2. What is the time of the recruitment?
3. The study population should be better defined:
- The authors report in the title and several times in the text that they considered
adult subjects; however, the range of age reported is 1.2-77 years.
- Inclusion and exclusion criteria are not reported.
- The study population baseline data (i.e BMI, sex, comorbidities and
autoimmune diseases) are not reported.
4. Could the authors report the sensitivity and specificity of the test?
5. The authors checked small bowel antibody deposits but they do not report any
interpretation of the findings. Is this test useful for this particular study?
Minor comments: in the first paragraphs of the result please change
(case 5 in Table 1) with (case 4 in Table 1)
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
assistant