Reviewer's report 
 Oxidised and total non-protein bound glutathione and related thiols in gallbladder bile of patients with Title: 
various gastrointestinal disorders. 
 2  30 October 2006 Version: Date: 
 Fiorella Piemonte Reviewer: 
Reviewer's report: 
General 
------------------------------------------------------------------------------- Major Compulsory Revisions (that the author must respond to before a decision on publication can be reached) 
1) the data should be presented as median and not as mean, given the extremely high SD. 
2) the thiol composition of gallbladder bile may be a reflection of some therapeutic trial. Indeed, the authors do not report any clinical information on the various patients and no data on the thiol composition in healthy subjects. 
------------------------------------------------------------------------------- 
Minor Essential Revisions (such as missing labels on figures, or the wrong use of a term, which the author 
can be trusted to correct) 
------------------------------------------------------------------------------- 
Discretionary Revisions (which the author can choose to ignore) 
 Unable to decide on acceptance or rejection until the authors have responded to the major What next?: 
compulsory revisions 
 An article of limited interest Level of interest: 
 Acceptable Quality of written English: 
 Yes Statistical review: 
Declaration of competing interests: 
'I declare that I have no competing interests'
Reviewer's report 
 Oxidised and total non-protein bound glutathione and related thiols in gallbladder bile of patients with Title: 
various gastrointestinal disorders. 
 2  30 October 2006 Version: Date: 
 Fiorella Piemonte Reviewer: 
Reviewer's report: 
General 
------------------------------------------------------------------------------- Major Compulsory Revisions (that the author must respond to before a decision on publication can be reached) 
1) the data should be presented as median and not as mean, given the extremely high SD. 
2) the thiol composition of gallbladder bile may be a reflection of some therapeutic trial. Indeed, the authors do not report any clinical information on the various patients and no data on the thiol composition in healthy subjects. 
------------------------------------------------------------------------------- 
Minor Essential Revisions (such as missing labels on figures, or the wrong use of a term, which the author 
can be trusted to correct) 
------------------------------------------------------------------------------- 
Discretionary Revisions (which the author can choose to ignore) 
 Unable to decide on acceptance or rejection until the authors have responded to the major What next?: 
compulsory revisions 
 An article of limited interest Level of interest: 
 Acceptable Quality of written English: 
 Yes Statistical review: 
Declaration of competing interests: 
'I declare that I have no competing interests'
Please review this paper.
user
Reviewer's report 
 Oxidised and total non-protein bound glutathione and related thiols in gallbladder bile of patients with Title: 
various gastrointestinal disorders. 
 2  30 October 2006 Version: Date: 
 Fiorella Piemonte Reviewer: 
Reviewer's report: 
General 
------------------------------------------------------------------------------- Major Compulsory Revisions (that the author must respond to before a decision on publication can be reached) 
1) the data should be presented as median and not as mean, given the extremely high SD. 
2) the thiol composition of gallbladder bile may be a reflection of some therapeutic trial. Indeed, the authors do not report any clinical information on the various patients and no data on the thiol composition in healthy subjects. 
------------------------------------------------------------------------------- 
Minor Essential Revisions (such as missing labels on figures, or the wrong use of a term, which the author 
can be trusted to correct) 
------------------------------------------------------------------------------- 
Discretionary Revisions (which the author can choose to ignore) 
 Unable to decide on acceptance or rejection until the authors have responded to the major What next?: 
compulsory revisions 
 An article of limited interest Level of interest: 
 Acceptable Quality of written English: 
 Yes Statistical review: 
Declaration of competing interests: 
'I declare that I have no competing interests'
assistant