Reviewer's report 
 Urodilatin Increases Natriuresis in Cirrhosis Patients with Sodium Retention. Title: 
 2  20 October 2006 Version: Date: 
 Yasuhiko Sugawara Reviewer: 
Reviewer's report: 
General comment 
The manuscript re-entitled “Effects of urodilatin on natriuresis in cirrhotic patients with sodium retention” by 
Carstens et al. has been properly revised according to our suggestion. On the whole this manuscript is acceptable for publication in BMC. I recognized that there are still some minor points which should be revised before publication. 
Minor comments. 
1. page 11, second paragraph. Both “URO was found to have no beneficial effect…” and “In a recent study on decompensated chronic heart failure…” need references. 
2. Third paragraph in page 11 starting with “On the other hand…” might be unnecessary and can be 
omitted. 3. Table 1. The title “summarizes the basal characteristics…” should be changed to “Summaries of the basal characteristics…”. 
4. Table 1. PP and MELD need explanations (spelling out) in the Table. 
 Accept after discretionary revisions What next?: 
 An article of importance in its field Level of interest: 
 Acceptable Quality of written English: 
 No Statistical review: 
Declaration of competing interests: 
I declare that I have no competing interests. 
Reviewer's report 
 Urodilatin Increases Natriuresis in Cirrhosis Patients with Sodium Retention. Title: 
 2  20 October 2006 Version: Date: 
 Yasuhiko Sugawara Reviewer: 
Reviewer's report: 
General comment 
The manuscript re-entitled “Effects of urodilatin on natriuresis in cirrhotic patients with sodium retention” by 
Carstens et al. has been properly revised according to our suggestion. On the whole this manuscript is acceptable for publication in BMC. I recognized that there are still some minor points which should be revised before publication. 
Minor comments. 
1. page 11, second paragraph. Both “URO was found to have no beneficial effect…” and “In a recent study on decompensated chronic heart failure…” need references. 
2. Third paragraph in page 11 starting with “On the other hand…” might be unnecessary and can be 
omitted. 3. Table 1. The title “summarizes the basal characteristics…” should be changed to “Summaries of the basal characteristics…”. 
4. Table 1. PP and MELD need explanations (spelling out) in the Table. 
 Accept after discretionary revisions What next?: 
 An article of importance in its field Level of interest: 
 Acceptable Quality of written English: 
 No Statistical review: 
Declaration of competing interests: 
I declare that I have no competing interests. 
Please review this paper.
user
Reviewer's report 
 Urodilatin Increases Natriuresis in Cirrhosis Patients with Sodium Retention. Title: 
 2  20 October 2006 Version: Date: 
 Yasuhiko Sugawara Reviewer: 
Reviewer's report: 
General comment 
The manuscript re-entitled “Effects of urodilatin on natriuresis in cirrhotic patients with sodium retention” by 
Carstens et al. has been properly revised according to our suggestion. On the whole this manuscript is acceptable for publication in BMC. I recognized that there are still some minor points which should be revised before publication. 
Minor comments. 
1. page 11, second paragraph. Both “URO was found to have no beneficial effect…” and “In a recent study on decompensated chronic heart failure…” need references. 
2. Third paragraph in page 11 starting with “On the other hand…” might be unnecessary and can be 
omitted. 3. Table 1. The title “summarizes the basal characteristics…” should be changed to “Summaries of the basal characteristics…”. 
4. Table 1. PP and MELD need explanations (spelling out) in the Table. 
 Accept after discretionary revisions What next?: 
 An article of importance in its field Level of interest: 
 Acceptable Quality of written English: 
 No Statistical review: 
Declaration of competing interests: 
I declare that I have no competing interests. 
assistant