Title: Additional chemoradiotherapy for superficial esophageal squamous cell carcinoma after
near-circumferential or full-circumferential noncurative endoscopic submucosal dissection: A
retrospective study
Version: 0 Date: 25 Dec 2023
Reviewer's report:
I think it is an important study to verify the efficiency of additional CRT after near or full-
circumferential noncurative ESD for superficial esophageal cancer. I have a few questions.
1. Page 12 Line 180. There is no discussion about the relationship between acute myeloid
leukemia and CRT. Please discuss it.
2. de novo esophageal stenosis is very important. There is a patient with refractory stenosis.
Please explain the mechanism of onset of de novo esophageal stenosis and for refractory stenosis
and detail to the factor to development of refractory stenosis.
Title: Additional chemoradiotherapy for superficial esophageal squamous cell carcinoma after
near-circumferential or full-circumferential noncurative endoscopic submucosal dissection: A
retrospective study
Version: 0 Date: 25 Dec 2023
Reviewer's report:
I think it is an important study to verify the efficiency of additional CRT after near or full-
circumferential noncurative ESD for superficial esophageal cancer. I have a few questions.
1. Page 12 Line 180. There is no discussion about the relationship between acute myeloid
leukemia and CRT. Please discuss it.
2. de novo esophageal stenosis is very important. There is a patient with refractory stenosis.
Please explain the mechanism of onset of de novo esophageal stenosis and for refractory stenosis
and detail to the factor to development of refractory stenosis.
Please review this paper.
user
Title: Additional chemoradiotherapy for superficial esophageal squamous cell carcinoma after
near-circumferential or full-circumferential noncurative endoscopic submucosal dissection: A
retrospective study
Version: 0 Date: 25 Dec 2023
Reviewer's report:
I think it is an important study to verify the efficiency of additional CRT after near or full-
circumferential noncurative ESD for superficial esophageal cancer. I have a few questions.
1. Page 12 Line 180. There is no discussion about the relationship between acute myeloid
leukemia and CRT. Please discuss it.
2. de novo esophageal stenosis is very important. There is a patient with refractory stenosis.
Please explain the mechanism of onset of de novo esophageal stenosis and for refractory stenosis
and detail to the factor to development of refractory stenosis.
assistant