Title: Construction of a prognostic risk model based on apoptosis-related genes to assess tumor
immune microenvironment and predict prognosis in hepatocellular carcinoma
Version: 1 Date: 11 Jul 2022
Reviewer's report:
This article by Wang and Ji aimed to establish a prognosis model based on apoptosis-related
genes (ARGs) to predict the outcome of HCC patients. Although it is indeed an urgent and
important matter to find an effective biomarker for the diagnosis and prognosis of HCC, this
topic has been investigated in several reports. The novelty is therefore limited. The following
are some suggestions that might help improve the manuscript.
1. Emphasize the novelty of this study. How is it different from previous results? What is its
value?
2. Compare the efficacy of this prognosis model to current clinical biomarkers, such as AFP.
3. Contrast and compare the results of previous reports that has also used ARGs as prognosis
biomarkers to your results.
4. Editing from a native speaker is required.
Title: Construction of a prognostic risk model based on apoptosis-related genes to assess tumor
immune microenvironment and predict prognosis in hepatocellular carcinoma
Version: 1 Date: 11 Jul 2022
Reviewer's report:
This article by Wang and Ji aimed to establish a prognosis model based on apoptosis-related
genes (ARGs) to predict the outcome of HCC patients. Although it is indeed an urgent and
important matter to find an effective biomarker for the diagnosis and prognosis of HCC, this
topic has been investigated in several reports. The novelty is therefore limited. The following
are some suggestions that might help improve the manuscript.
1. Emphasize the novelty of this study. How is it different from previous results? What is its
value?
2. Compare the efficacy of this prognosis model to current clinical biomarkers, such as AFP.
3. Contrast and compare the results of previous reports that has also used ARGs as prognosis
biomarkers to your results.
4. Editing from a native speaker is required.
Please review this paper.
user
Title: Construction of a prognostic risk model based on apoptosis-related genes to assess tumor
immune microenvironment and predict prognosis in hepatocellular carcinoma
Version: 1 Date: 11 Jul 2022
Reviewer's report:
This article by Wang and Ji aimed to establish a prognosis model based on apoptosis-related
genes (ARGs) to predict the outcome of HCC patients. Although it is indeed an urgent and
important matter to find an effective biomarker for the diagnosis and prognosis of HCC, this
topic has been investigated in several reports. The novelty is therefore limited. The following
are some suggestions that might help improve the manuscript.
1. Emphasize the novelty of this study. How is it different from previous results? What is its
value?
2. Compare the efficacy of this prognosis model to current clinical biomarkers, such as AFP.
3. Contrast and compare the results of previous reports that has also used ARGs as prognosis
biomarkers to your results.
4. Editing from a native speaker is required.
assistant