Title: Risk factors for gastric mucosa lesion in critically ill patients undergoing endoscopy for
percutaneous gastrostomy: a case-control study
Version: 1 Date: 22 Sep 2024
Reviewer's report:
1. There is little relation of PEG implantation to gastric mucosal damage investigated in this
study. It only provides an opportunity to examine the gastric mucosa by endoscope.
2. Besides high dose PPI that was excluded in this study, what was the regimen used for stress
ulcer prophylaxis by these patients in this study, PPI or H2 blocker?
3. What were the indications for these patients in ICU to receive PEG insertion? PEG insertion
is often not considered for patient with unstable condition or poor life expectancy , such as ICU
patients.
4. Did these patients receive NG insertion and enteral nutrition before PEG implantation? Enteral
nutrition has a significant impact on the occurrence of stress ulcer.
5. Was there any difference for clinical conditions before endoscopic examination between
those patients with gastric mucosal lesion and without, such as sign of bleeding, vital signs or
APACHE II score?
6. Was there any difference for PEG associated complications between those patients with
gastric mucosal lesion and without?
Title: Risk factors for gastric mucosa lesion in critically ill patients undergoing endoscopy for
percutaneous gastrostomy: a case-control study
Version: 1 Date: 22 Sep 2024
Reviewer's report:
1. There is little relation of PEG implantation to gastric mucosal damage investigated in this
study. It only provides an opportunity to examine the gastric mucosa by endoscope.
2. Besides high dose PPI that was excluded in this study, what was the regimen used for stress
ulcer prophylaxis by these patients in this study, PPI or H2 blocker?
3. What were the indications for these patients in ICU to receive PEG insertion? PEG insertion
is often not considered for patient with unstable condition or poor life expectancy , such as ICU
patients.
4. Did these patients receive NG insertion and enteral nutrition before PEG implantation? Enteral
nutrition has a significant impact on the occurrence of stress ulcer.
5. Was there any difference for clinical conditions before endoscopic examination between
those patients with gastric mucosal lesion and without, such as sign of bleeding, vital signs or
APACHE II score?
6. Was there any difference for PEG associated complications between those patients with
gastric mucosal lesion and without?
Please review this paper.
user
Title: Risk factors for gastric mucosa lesion in critically ill patients undergoing endoscopy for
percutaneous gastrostomy: a case-control study
Version: 1 Date: 22 Sep 2024
Reviewer's report:
1. There is little relation of PEG implantation to gastric mucosal damage investigated in this
study. It only provides an opportunity to examine the gastric mucosa by endoscope.
2. Besides high dose PPI that was excluded in this study, what was the regimen used for stress
ulcer prophylaxis by these patients in this study, PPI or H2 blocker?
3. What were the indications for these patients in ICU to receive PEG insertion? PEG insertion
is often not considered for patient with unstable condition or poor life expectancy , such as ICU
patients.
4. Did these patients receive NG insertion and enteral nutrition before PEG implantation? Enteral
nutrition has a significant impact on the occurrence of stress ulcer.
5. Was there any difference for clinical conditions before endoscopic examination between
those patients with gastric mucosal lesion and without, such as sign of bleeding, vital signs or
APACHE II score?
6. Was there any difference for PEG associated complications between those patients with
gastric mucosal lesion and without?
assistant