Reviewer's report
Title:HBV DNA level, not liver stiffness value, could predict significant liver
fibrosis in HBeAg negative chronic hepatitis B patients with liver biopsy indication
as AASLD and APASL guidelines
Version:2Date:8 October 2014
Reviewer: Cosmas Rinaldi Lesmana
Reviewer's report:
Major Concerns:
1. The sample size is small.
2. Could contain selection bias as the authors highlight in the discussion.
3. It was not clear enough the age selection criteria based.
4. There is no clear explanation in the discussion about more fibrosis in the
younger age.
Minor Concern:
The language need to be polished.
Level of interest: An article of insufficient interest to warrant publication in a
scientific/medical journal
Quality of written English: Needs some language corrections before being
published
Statistical review: Yes, and I have assessed the statistics in my report.
Declaration of competing interests:
No conflict of interest.
Reviewer's report
Title:HBV DNA level, not liver stiffness value, could predict significant liver
fibrosis in HBeAg negative chronic hepatitis B patients with liver biopsy indication
as AASLD and APASL guidelines
Version:2Date:8 October 2014
Reviewer: Cosmas Rinaldi Lesmana
Reviewer's report:
Major Concerns:
1. The sample size is small.
2. Could contain selection bias as the authors highlight in the discussion.
3. It was not clear enough the age selection criteria based.
4. There is no clear explanation in the discussion about more fibrosis in the
younger age.
Minor Concern:
The language need to be polished.
Level of interest: An article of insufficient interest to warrant publication in a
scientific/medical journal
Quality of written English: Needs some language corrections before being
published
Statistical review: Yes, and I have assessed the statistics in my report.
Declaration of competing interests:
No conflict of interest.
Please review this paper.
user
Reviewer's report
Title:HBV DNA level, not liver stiffness value, could predict significant liver
fibrosis in HBeAg negative chronic hepatitis B patients with liver biopsy indication
as AASLD and APASL guidelines
Version:2Date:8 October 2014
Reviewer: Cosmas Rinaldi Lesmana
Reviewer's report:
Major Concerns:
1. The sample size is small.
2. Could contain selection bias as the authors highlight in the discussion.
3. It was not clear enough the age selection criteria based.
4. There is no clear explanation in the discussion about more fibrosis in the
younger age.
Minor Concern:
The language need to be polished.
Level of interest: An article of insufficient interest to warrant publication in a
scientific/medical journal
Quality of written English: Needs some language corrections before being
published
Statistical review: Yes, and I have assessed the statistics in my report.
Declaration of competing interests:
No conflict of interest.
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