Title: Prognostic Value of Neutrophil-to-Lymphocyte Ratio in Septic Patients with Liver
Cirrhosis: A Cohort Study
Version: 0 Date: 23 Apr 2025
Reviewer:  Giuseppe Guido Maria Scarlata
Reviewer's report:
In the present paper the Authors showed how NLR is an independent risk factor for in-hospital
all-cause death in septic patients with cirrhosis, and it can guide interventions for at high-risk
population. I have some revisions to improve it:
1. Some odds ratios  are reported before the confidence intervals, while others are embedded
within text or reversed. Please, revise it for improved readability.
2. I suggest to cite this recent paper about the use of this biomarker in cirrhotic patients (doi:
10.3390/medicina60111854);
3. The sensitivity, specificity, and optimal cut-off value for NLR are not reported. Please, fix it.
4. Please, justify variable selection for multivariable models;
5. Provide an abbreviation list and define all abbreviations at first use for improved readability.
Title: Prognostic Value of Neutrophil-to-Lymphocyte Ratio in Septic Patients with Liver
Cirrhosis: A Cohort Study
Version: 0 Date: 23 Apr 2025
Reviewer:  Giuseppe Guido Maria Scarlata
Reviewer's report:
In the present paper the Authors showed how NLR is an independent risk factor for in-hospital
all-cause death in septic patients with cirrhosis, and it can guide interventions for at high-risk
population. I have some revisions to improve it:
1. Some odds ratios  are reported before the confidence intervals, while others are embedded
within text or reversed. Please, revise it for improved readability.
2. I suggest to cite this recent paper about the use of this biomarker in cirrhotic patients (doi:
10.3390/medicina60111854);
3. The sensitivity, specificity, and optimal cut-off value for NLR are not reported. Please, fix it.
4. Please, justify variable selection for multivariable models;
5. Provide an abbreviation list and define all abbreviations at first use for improved readability.
Please review this paper.
user
Title: Prognostic Value of Neutrophil-to-Lymphocyte Ratio in Septic Patients with Liver
Cirrhosis: A Cohort Study
Version: 0 Date: 23 Apr 2025
Reviewer:  Giuseppe Guido Maria Scarlata
Reviewer's report:
In the present paper the Authors showed how NLR is an independent risk factor for in-hospital
all-cause death in septic patients with cirrhosis, and it can guide interventions for at high-risk
population. I have some revisions to improve it:
1. Some odds ratios  are reported before the confidence intervals, while others are embedded
within text or reversed. Please, revise it for improved readability.
2. I suggest to cite this recent paper about the use of this biomarker in cirrhotic patients (doi:
10.3390/medicina60111854);
3. The sensitivity, specificity, and optimal cut-off value for NLR are not reported. Please, fix it.
4. Please, justify variable selection for multivariable models;
5. Provide an abbreviation list and define all abbreviations at first use for improved readability.
assistant