Title: SPOCK1 and POSTN are valuable prognostic biomarkers and correlate with tumor
immune infiltrates in colorectal cancer
Version: 4 Date: 14 Nov 2022
Reviewer's report:
With the addition of scRNAseq data and other changes that the authors has made, the manuscript
seems in much better shape. However, there are still adjustment that I would like to recommend.
1. In result 3.8, additional reference should be added since CAF was not explained in any prior
sentences.
2. In figure 9E, does intensity of SPOCK1 and POSTN include only stromal areas or also tumor
cells?
Title: SPOCK1 and POSTN are valuable prognostic biomarkers and correlate with tumor
immune infiltrates in colorectal cancer
Version: 4 Date: 14 Nov 2022
Reviewer's report:
With the addition of scRNAseq data and other changes that the authors has made, the manuscript
seems in much better shape. However, there are still adjustment that I would like to recommend.
1. In result 3.8, additional reference should be added since CAF was not explained in any prior
sentences.
2. In figure 9E, does intensity of SPOCK1 and POSTN include only stromal areas or also tumor
cells?
Please review this paper.
user
Title: SPOCK1 and POSTN are valuable prognostic biomarkers and correlate with tumor
immune infiltrates in colorectal cancer
Version: 4 Date: 14 Nov 2022
Reviewer's report:
With the addition of scRNAseq data and other changes that the authors has made, the manuscript
seems in much better shape. However, there are still adjustment that I would like to recommend.
1. In result 3.8, additional reference should be added since CAF was not explained in any prior
sentences.
2. In figure 9E, does intensity of SPOCK1 and POSTN include only stromal areas or also tumor
cells?
assistant