Title: The Impact of Relaxing the Requirements for Dyspeptic Symptom Onset Frequency or
Duration in Rome IV Criteria on the Symptom Pattern and Diagnosis of Functional Dyspepsia
Version: 4 Date: 04 Oct 2024
Reviewer's report:
Congratulations on the work provided. Compared to last review, it is a step forward.
However, first of all, my biggest concern remains the "own questionnaire". Apart from the
early satiety definition as mentioned earlier, I see that in the questionnaire Q2 you asked about
"retrosternal burning sensation" (= heartburn) and then about "heartburn". It is the same. In the
discussion and table 3, it is "acid reflux" and "heartburn". I think the authors should use one
translation. And just make a statement about the fact that the Rome questionnaire has not been
used (in the limitations).
Furthermore, the manuscript still needs language polishing.
67: "cure" needs to be "explanation"
70: FD is considered a heterogeneous condition… (remove "as")
71: which may negatively impact the efficacy of … (remove "on")
81: duration criteria for at least (instead of "of at least")
88: maybe refer to "Rome Foundation Clinical Diagnostic Criteria for Disorders of Gut-Brain
Interaction. Drossman, Douglas A.Tack, Jan et al. Gastroenterology, Volume 162, Issue 3, 675
– 679)"
115: (ii) patients who were pregnant or lactating
117-119: (vi) current use of steroids or nonsteroidal anti-inflammatory drugs; (vii) patients who
declined to participate in this study.
191: meet the Rome IV criteria (not "meets")
196: age (Supplementary Table 2), gender (Supplementary Table 1)
239: "proposed to subdivide"
Table 3: maybe explain shortly what p# is
No further comments
Title: The Impact of Relaxing the Requirements for Dyspeptic Symptom Onset Frequency or
Duration in Rome IV Criteria on the Symptom Pattern and Diagnosis of Functional Dyspepsia
Version: 4 Date: 04 Oct 2024
Reviewer's report:
Congratulations on the work provided. Compared to last review, it is a step forward.
However, first of all, my biggest concern remains the "own questionnaire". Apart from the
early satiety definition as mentioned earlier, I see that in the questionnaire Q2 you asked about
"retrosternal burning sensation" (= heartburn) and then about "heartburn". It is the same. In the
discussion and table 3, it is "acid reflux" and "heartburn". I think the authors should use one
translation. And just make a statement about the fact that the Rome questionnaire has not been
used (in the limitations).
Furthermore, the manuscript still needs language polishing.
67: "cure" needs to be "explanation"
70: FD is considered a heterogeneous condition… (remove "as")
71: which may negatively impact the efficacy of … (remove "on")
81: duration criteria for at least (instead of "of at least")
88: maybe refer to "Rome Foundation Clinical Diagnostic Criteria for Disorders of Gut-Brain
Interaction. Drossman, Douglas A.Tack, Jan et al. Gastroenterology, Volume 162, Issue 3, 675
– 679)"
115: (ii) patients who were pregnant or lactating
117-119: (vi) current use of steroids or nonsteroidal anti-inflammatory drugs; (vii) patients who
declined to participate in this study.
191: meet the Rome IV criteria (not "meets")
196: age (Supplementary Table 2), gender (Supplementary Table 1)
239: "proposed to subdivide"
Table 3: maybe explain shortly what p# is
No further comments
Please review this paper.
user
Title: The Impact of Relaxing the Requirements for Dyspeptic Symptom Onset Frequency or
Duration in Rome IV Criteria on the Symptom Pattern and Diagnosis of Functional Dyspepsia
Version: 4 Date: 04 Oct 2024
Reviewer's report:
Congratulations on the work provided. Compared to last review, it is a step forward.
However, first of all, my biggest concern remains the "own questionnaire". Apart from the
early satiety definition as mentioned earlier, I see that in the questionnaire Q2 you asked about
"retrosternal burning sensation" (= heartburn) and then about "heartburn". It is the same. In the
discussion and table 3, it is "acid reflux" and "heartburn". I think the authors should use one
translation. And just make a statement about the fact that the Rome questionnaire has not been
used (in the limitations).
Furthermore, the manuscript still needs language polishing.
67: "cure" needs to be "explanation"
70: FD is considered a heterogeneous condition… (remove "as")
71: which may negatively impact the efficacy of … (remove "on")
81: duration criteria for at least (instead of "of at least")
88: maybe refer to "Rome Foundation Clinical Diagnostic Criteria for Disorders of Gut-Brain
Interaction. Drossman, Douglas A.Tack, Jan et al. Gastroenterology, Volume 162, Issue 3, 675
– 679)"
115: (ii) patients who were pregnant or lactating
117-119: (vi) current use of steroids or nonsteroidal anti-inflammatory drugs; (vii) patients who
declined to participate in this study.
191: meet the Rome IV criteria (not "meets")
196: age (Supplementary Table 2), gender (Supplementary Table 1)
239: "proposed to subdivide"
Table 3: maybe explain shortly what p# is
No further comments
assistant