Reviewer ’s report  
 
Title: Abdominal migraine in children: Association between gastric motility parameters and 
clinical characteristics  
 
 
Version: 0 Date: 27 Oct 2015  
 
 
Reviewer: Noorizan  Abdul Majid  
 
 
Reviewer's report:  
 
Generally this is goo d study. There is yet any study thus far that look into the gastric motility and 
abdominal migraine and correlations with their clinical symptoms. I applaud the authors' effort. 
Abdominal migraine being uncommon, I can understand the long duration that the  author took to 
recruit the patients. However it is desirable for the author to include the description of the study 
design and show the adequate sample size needed. The assessment of symptom severity and 
scoring system was not clearly explained. If these were based on previous validated scoring 
system, then the author should include the reference and if this is not the case the author should 
described them clearly and whether any validation of the scoring system made.It was not 
mentioned in the methodology  section whether the investigator who performed the ultrasound 
was blinded to the diagnosis of cases or control. Although in the 'discussion section' it was 
mentioned briefly the investigator was not blinded in that she did  know that she is dealing with 
GIT cases, it is important to know whether she is blinded to cases and controls.There was also no 
mentioned whether intraobserver reliability was performed.  
 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
No 
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
Yes 
Are the conclusions drawn ade quately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in the manuscript or would you recommend an 
additional statistical review?  
If an additional statistical  review is recommended, please specify what aspects require further 
assessment in your comments to the editors.  
 
I am able to assess the statistics  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Acceptable  
 
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following questions:  
 
1. Have you in the past five y ears received reimbursements, fees, funding, or salary from 
an organisation that may in any way gain or lose financially from the publication of this  
manuscript, either now or in the future?  
 
2. Do you hold any stocks or shares in an organisation that may i n any way gain or lose  
financially from the publication of this manuscript, either now or in the future?  
 
3. Do you hold or are you currently applying for any patents relating to the content of the  
manuscript?  
 
4. Have you received reimbursements, fees, funding, or salary from an organization that 
holds  or has applied for patents relating to the content of the manuscript?  
 
5. Do you have any other financial competing interests?  
 
6. Do you have any non -financial com peting interests in relation to this paper?  
 
If you can answer no to all of the above, write 'I declare that I have no competing interests' 
below.  If your reply is yes to any, please give details below.  
 
I declare that I have no competing interests  
 
I agree to the open peer review policy of the journal. I understand that my name will be included  
on my report to the authors and, if the manuscript is accepted for publication, my named report  
including any attachments I upload will be posted on the website along  with the authors'  
responses. I agree for my report to be made available under an Open Access Creative Commons  
CC-BY license ( http://creativecommons.org/licenses/by/4.0/ ). I understand that any comments  
which I do not wish to be included in my named report  can be included as confidential comments  
to the editors, which will not be published.  
 
I agree to the open peer review policy of the journal  
Reviewer ’s report  
 
Title: Abdominal migraine in children: Association between gastric motility parameters and 
clinical characteristics  
 
 
Version: 0 Date: 27 Oct 2015  
 
 
Reviewer: Noorizan  Abdul Majid  
 
 
Reviewer's report:  
 
Generally this is goo d study. There is yet any study thus far that look into the gastric motility and 
abdominal migraine and correlations with their clinical symptoms. I applaud the authors' effort. 
Abdominal migraine being uncommon, I can understand the long duration that the  author took to 
recruit the patients. However it is desirable for the author to include the description of the study 
design and show the adequate sample size needed. The assessment of symptom severity and 
scoring system was not clearly explained. If these were based on previous validated scoring 
system, then the author should include the reference and if this is not the case the author should 
described them clearly and whether any validation of the scoring system made.It was not 
mentioned in the methodology  section whether the investigator who performed the ultrasound 
was blinded to the diagnosis of cases or control. Although in the 'discussion section' it was 
mentioned briefly the investigator was not blinded in that she did  know that she is dealing with 
GIT cases, it is important to know whether she is blinded to cases and controls.There was also no 
mentioned whether intraobserver reliability was performed.  
 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
No 
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
Yes 
Are the conclusions drawn ade quately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in the manuscript or would you recommend an 
additional statistical review?  
If an additional statistical  review is recommended, please specify what aspects require further 
assessment in your comments to the editors.  
 
I am able to assess the statistics  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Acceptable  
 
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following questions:  
 
1. Have you in the past five y ears received reimbursements, fees, funding, or salary from 
an organisation that may in any way gain or lose financially from the publication of this  
manuscript, either now or in the future?  
 
2. Do you hold any stocks or shares in an organisation that may i n any way gain or lose  
financially from the publication of this manuscript, either now or in the future?  
 
3. Do you hold or are you currently applying for any patents relating to the content of the  
manuscript?  
 
4. Have you received reimbursements, fees, funding, or salary from an organization that 
holds  or has applied for patents relating to the content of the manuscript?  
 
5. Do you have any other financial competing interests?  
 
6. Do you have any non -financial com peting interests in relation to this paper?  
 
If you can answer no to all of the above, write 'I declare that I have no competing interests' 
below.  If your reply is yes to any, please give details below.  
 
I declare that I have no competing interests  
 
I agree to the open peer review policy of the journal. I understand that my name will be included  
on my report to the authors and, if the manuscript is accepted for publication, my named report  
including any attachments I upload will be posted on the website along  with the authors'  
responses. I agree for my report to be made available under an Open Access Creative Commons  
CC-BY license ( http://creativecommons.org/licenses/by/4.0/ ). I understand that any comments  
which I do not wish to be included in my named report  can be included as confidential comments  
to the editors, which will not be published.  
 
I agree to the open peer review policy of the journal  
Please review this paper.
user
Reviewer ’s report  
 
Title: Abdominal migraine in children: Association between gastric motility parameters and 
clinical characteristics  
 
 
Version: 0 Date: 27 Oct 2015  
 
 
Reviewer: Noorizan  Abdul Majid  
 
 
Reviewer's report:  
 
Generally this is goo d study. There is yet any study thus far that look into the gastric motility and 
abdominal migraine and correlations with their clinical symptoms. I applaud the authors' effort. 
Abdominal migraine being uncommon, I can understand the long duration that the  author took to 
recruit the patients. However it is desirable for the author to include the description of the study 
design and show the adequate sample size needed. The assessment of symptom severity and 
scoring system was not clearly explained. If these were based on previous validated scoring 
system, then the author should include the reference and if this is not the case the author should 
described them clearly and whether any validation of the scoring system made.It was not 
mentioned in the methodology  section whether the investigator who performed the ultrasound 
was blinded to the diagnosis of cases or control. Although in the 'discussion section' it was 
mentioned briefly the investigator was not blinded in that she did  know that she is dealing with 
GIT cases, it is important to know whether she is blinded to cases and controls.There was also no 
mentioned whether intraobserver reliability was performed.  
 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
No 
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
Yes 
Are the conclusions drawn ade quately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in the manuscript or would you recommend an 
additional statistical review?  
If an additional statistical  review is recommended, please specify what aspects require further 
assessment in your comments to the editors.  
 
I am able to assess the statistics  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Acceptable  
 
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following questions:  
 
1. Have you in the past five y ears received reimbursements, fees, funding, or salary from 
an organisation that may in any way gain or lose financially from the publication of this  
manuscript, either now or in the future?  
 
2. Do you hold any stocks or shares in an organisation that may i n any way gain or lose  
financially from the publication of this manuscript, either now or in the future?  
 
3. Do you hold or are you currently applying for any patents relating to the content of the  
manuscript?  
 
4. Have you received reimbursements, fees, funding, or salary from an organization that 
holds  or has applied for patents relating to the content of the manuscript?  
 
5. Do you have any other financial competing interests?  
 
6. Do you have any non -financial com peting interests in relation to this paper?  
 
If you can answer no to all of the above, write 'I declare that I have no competing interests' 
below.  If your reply is yes to any, please give details below.  
 
I declare that I have no competing interests  
 
I agree to the open peer review policy of the journal. I understand that my name will be included  
on my report to the authors and, if the manuscript is accepted for publication, my named report  
including any attachments I upload will be posted on the website along  with the authors'  
responses. I agree for my report to be made available under an Open Access Creative Commons  
CC-BY license ( http://creativecommons.org/licenses/by/4.0/ ). I understand that any comments  
which I do not wish to be included in my named report  can be included as confidential comments  
to the editors, which will not be published.  
 
I agree to the open peer review policy of the journal  
assistant