Reviewer's report
Title:Effectiveness of CO2-insufflated Endoscopic Submucosal Dissection with
the duodenal balloon occlusion method for early esophageal or gastric cancer
Version: 4Date:20 March 2012
Reviewer: Yutaka Saito
Reviewer's report:
1) The References were incorrect.
Ref. No. 11 is paper about CO2 insufflation for colorectal ESD not for routine CS.
The other paper about CO2 use for colorectal ESD is as below;
Kikuchi T, et al. Transcutaneous monitoring of partial pressure of carbon dioxide
during endoscopic submucosal dissection of early colorectal neoplasia with
carbon dioxide insufflation: a prospective study. Surg Endosc. 2010
Sep;24(9):2231-5. Epub 2010 Feb 23.
2) Introduction
The authors described that “ little investigation has been performed on how CO 2
gas used in ESD for the treatment of early esophageal or gastric cancer affects
the human body.” In the Introduction section but this description is incorrect.
The usefulness and safety of CO2 use in upper GI ESD were already reported.
Please refer to papers as follows;
Nonaka S, et al. Safety of carbon dioxide insufflation for upper gastrointestinal
tract endoscopic treatment of patients under deep sedation. Surg Endosc. 2010
Jul;24(7):1638-45. Epub 2010 Jan 28.
Maeda Y, et al. A pilot study to assess mediastinal emphysema after esophageal
endoscopic submucosal dissection with carbon dioxide insufflation. Endoscopy.
2012 Mar 9. [Epub ahead of print]
Uemura M, et al. Effects of Carbon Dioxide Insufflation in Esophageal
Endoscopic Submucosal Dissection. Hepatogastroenterology. 2011 Oct
14;59(115-116). doi: 10.5754/hge11547. [Epub ahead of print]
3) Discussion
The same issue in the introduction
The authors described as “The advantage of CO 2 -insufflated ESD for early
colorectal cancer has been previously reported [5]. However, no study has
scientifically examined the influences of CO 2 insufflation on the human body
during ESD of the upper gastrointestinal (GI) tract. “
This is not correct. Please refer to appropriate papers.
According to the previous papers, upper GI ESD using CO2 can be conducted
safely so please discuss the comparison with these previously reported papers.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: Yes, but I do not feel adequately qualified to assess the
statistics.
Declaration of competing interests:
I declare that I have no competing interests
Reviewer's report
Title:Effectiveness of CO2-insufflated Endoscopic Submucosal Dissection with
the duodenal balloon occlusion method for early esophageal or gastric cancer
Version: 4Date:20 March 2012
Reviewer: Yutaka Saito
Reviewer's report:
1) The References were incorrect.
Ref. No. 11 is paper about CO2 insufflation for colorectal ESD not for routine CS.
The other paper about CO2 use for colorectal ESD is as below;
Kikuchi T, et al. Transcutaneous monitoring of partial pressure of carbon dioxide
during endoscopic submucosal dissection of early colorectal neoplasia with
carbon dioxide insufflation: a prospective study. Surg Endosc. 2010
Sep;24(9):2231-5. Epub 2010 Feb 23.
2) Introduction
The authors described that “ little investigation has been performed on how CO 2
gas used in ESD for the treatment of early esophageal or gastric cancer affects
the human body.” In the Introduction section but this description is incorrect.
The usefulness and safety of CO2 use in upper GI ESD were already reported.
Please refer to papers as follows;
Nonaka S, et al. Safety of carbon dioxide insufflation for upper gastrointestinal
tract endoscopic treatment of patients under deep sedation. Surg Endosc. 2010
Jul;24(7):1638-45. Epub 2010 Jan 28.
Maeda Y, et al. A pilot study to assess mediastinal emphysema after esophageal
endoscopic submucosal dissection with carbon dioxide insufflation. Endoscopy.
2012 Mar 9. [Epub ahead of print]
Uemura M, et al. Effects of Carbon Dioxide Insufflation in Esophageal
Endoscopic Submucosal Dissection. Hepatogastroenterology. 2011 Oct
14;59(115-116). doi: 10.5754/hge11547. [Epub ahead of print]
3) Discussion
The same issue in the introduction
The authors described as “The advantage of CO 2 -insufflated ESD for early
colorectal cancer has been previously reported [5]. However, no study has
scientifically examined the influences of CO 2 insufflation on the human body
during ESD of the upper gastrointestinal (GI) tract. “
This is not correct. Please refer to appropriate papers.
According to the previous papers, upper GI ESD using CO2 can be conducted
safely so please discuss the comparison with these previously reported papers.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: Yes, but I do not feel adequately qualified to assess the
statistics.
Declaration of competing interests:
I declare that I have no competing interests
Please review this paper.
user
Reviewer's report
Title:Effectiveness of CO2-insufflated Endoscopic Submucosal Dissection with
the duodenal balloon occlusion method for early esophageal or gastric cancer
Version: 4Date:20 March 2012
Reviewer: Yutaka Saito
Reviewer's report:
1) The References were incorrect.
Ref. No. 11 is paper about CO2 insufflation for colorectal ESD not for routine CS.
The other paper about CO2 use for colorectal ESD is as below;
Kikuchi T, et al. Transcutaneous monitoring of partial pressure of carbon dioxide
during endoscopic submucosal dissection of early colorectal neoplasia with
carbon dioxide insufflation: a prospective study. Surg Endosc. 2010
Sep;24(9):2231-5. Epub 2010 Feb 23.
2) Introduction
The authors described that “ little investigation has been performed on how CO 2
gas used in ESD for the treatment of early esophageal or gastric cancer affects
the human body.” In the Introduction section but this description is incorrect.
The usefulness and safety of CO2 use in upper GI ESD were already reported.
Please refer to papers as follows;
Nonaka S, et al. Safety of carbon dioxide insufflation for upper gastrointestinal
tract endoscopic treatment of patients under deep sedation. Surg Endosc. 2010
Jul;24(7):1638-45. Epub 2010 Jan 28.
Maeda Y, et al. A pilot study to assess mediastinal emphysema after esophageal
endoscopic submucosal dissection with carbon dioxide insufflation. Endoscopy.
2012 Mar 9. [Epub ahead of print]
Uemura M, et al. Effects of Carbon Dioxide Insufflation in Esophageal
Endoscopic Submucosal Dissection. Hepatogastroenterology. 2011 Oct
14;59(115-116). doi: 10.5754/hge11547. [Epub ahead of print]
3) Discussion
The same issue in the introduction
The authors described as “The advantage of CO 2 -insufflated ESD for early
colorectal cancer has been previously reported [5]. However, no study has
scientifically examined the influences of CO 2 insufflation on the human body
during ESD of the upper gastrointestinal (GI) tract. “
This is not correct. Please refer to appropriate papers.
According to the previous papers, upper GI ESD using CO2 can be conducted
safely so please discuss the comparison with these previously reported papers.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: Yes, but I do not feel adequately qualified to assess the
statistics.
Declaration of competing interests:
I declare that I have no competing interests
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