Title: TPH1 gene polymorphism rs211105 is associated with serotonin and tryptophan
hydroxylase 1 concentrations in acute pancreatitis patients
Version: 1 Date: 17 Oct 2021
Reviewer's report:
The results did not provide evidence that rs211105 has a "causal effect"  on acute pancreatitis
because the study design is a cross-sectional study. Maybe some adjustment for the title
from "TPH1 gene polymorphism rs211105 influences serotonin and tryptophan hydroxylase
1 concentration in acute pancreatitis patients" to  "TPH1 gene polymorphism rs211105 is
associated with serotonin and tryptophan hydroxylase 1 concentration in acute pancreatitis
patients" is more appropriate.
Title: TPH1 gene polymorphism rs211105 is associated with serotonin and tryptophan
hydroxylase 1 concentrations in acute pancreatitis patients
Version: 1 Date: 17 Oct 2021
Reviewer's report:
The results did not provide evidence that rs211105 has a "causal effect"  on acute pancreatitis
because the study design is a cross-sectional study. Maybe some adjustment for the title
from "TPH1 gene polymorphism rs211105 influences serotonin and tryptophan hydroxylase
1 concentration in acute pancreatitis patients" to  "TPH1 gene polymorphism rs211105 is
associated with serotonin and tryptophan hydroxylase 1 concentration in acute pancreatitis
patients" is more appropriate.
Please review this paper.
user
Title: TPH1 gene polymorphism rs211105 is associated with serotonin and tryptophan
hydroxylase 1 concentrations in acute pancreatitis patients
Version: 1 Date: 17 Oct 2021
Reviewer's report:
The results did not provide evidence that rs211105 has a "causal effect"  on acute pancreatitis
because the study design is a cross-sectional study. Maybe some adjustment for the title
from "TPH1 gene polymorphism rs211105 influences serotonin and tryptophan hydroxylase
1 concentration in acute pancreatitis patients" to  "TPH1 gene polymorphism rs211105 is
associated with serotonin and tryptophan hydroxylase 1 concentration in acute pancreatitis
patients" is more appropriate.
assistant