Reviewer's report
Title:Using an oblique incident laser beam to measure the optical properties of
stomach mucosa/submucosa tissue
Version: 4Date:16 December 2008
Reviewer: Alexey N Bashkatov
Reviewer's report:
In this paper the authors investigated the optical properties of stomach tissues.
The study is interesting and important for tissue optics, and the data presented in
the paper can be used for many medical applications. Therefore, the paper of
Wei et al. is important and relevant and so the paper may be accepted to
publishing in BMC Gastroenterology. However, some remarks should be taken
into account before the acceptance. They are listed below.
1. In the Section "Sample preparation" of this paper, the authors write that tissue
samples were "stored in a refrigerator at -70°C before measurement". However,
the authors not discuss the storage method from point of view of validity of the
tissue optical properties. At the same time the both freezing and thawing cause
significant changes in tissue optical properties and, so, the discussion has to be
added.
2. It is not clear how the images from the CCD were converted to the tissue
optical properties. The procedure has to be presented.
3. The discussion section merely describes the data presented in the figures. The
authors also repeat the same few sentences when they present results for the
various parameters, simply changing the numerical values where necessary.
This makes the section long and difficult to read. Thus, this section cannot be
accepted as discussion.
4. The language of the paper should be improved, for there are some
imperfections concerning grammar and style.
Level of interest: An article of limited interest
Quality of written English: Needs some language corrections before being
published
Statistical review: Yes, but I do not feel adequately qualified to assess the
statistics.
Declaration of competing interests:
I declare that I have no competing interests
Reviewer's report
Title:Using an oblique incident laser beam to measure the optical properties of
stomach mucosa/submucosa tissue
Version: 4Date:16 December 2008
Reviewer: Alexey N Bashkatov
Reviewer's report:
In this paper the authors investigated the optical properties of stomach tissues.
The study is interesting and important for tissue optics, and the data presented in
the paper can be used for many medical applications. Therefore, the paper of
Wei et al. is important and relevant and so the paper may be accepted to
publishing in BMC Gastroenterology. However, some remarks should be taken
into account before the acceptance. They are listed below.
1. In the Section "Sample preparation" of this paper, the authors write that tissue
samples were "stored in a refrigerator at -70°C before measurement". However,
the authors not discuss the storage method from point of view of validity of the
tissue optical properties. At the same time the both freezing and thawing cause
significant changes in tissue optical properties and, so, the discussion has to be
added.
2. It is not clear how the images from the CCD were converted to the tissue
optical properties. The procedure has to be presented.
3. The discussion section merely describes the data presented in the figures. The
authors also repeat the same few sentences when they present results for the
various parameters, simply changing the numerical values where necessary.
This makes the section long and difficult to read. Thus, this section cannot be
accepted as discussion.
4. The language of the paper should be improved, for there are some
imperfections concerning grammar and style.
Level of interest: An article of limited interest
Quality of written English: Needs some language corrections before being
published
Statistical review: Yes, but I do not feel adequately qualified to assess the
statistics.
Declaration of competing interests:
I declare that I have no competing interests
Please review this paper.
user
Reviewer's report
Title:Using an oblique incident laser beam to measure the optical properties of
stomach mucosa/submucosa tissue
Version: 4Date:16 December 2008
Reviewer: Alexey N Bashkatov
Reviewer's report:
In this paper the authors investigated the optical properties of stomach tissues.
The study is interesting and important for tissue optics, and the data presented in
the paper can be used for many medical applications. Therefore, the paper of
Wei et al. is important and relevant and so the paper may be accepted to
publishing in BMC Gastroenterology. However, some remarks should be taken
into account before the acceptance. They are listed below.
1. In the Section "Sample preparation" of this paper, the authors write that tissue
samples were "stored in a refrigerator at -70°C before measurement". However,
the authors not discuss the storage method from point of view of validity of the
tissue optical properties. At the same time the both freezing and thawing cause
significant changes in tissue optical properties and, so, the discussion has to be
added.
2. It is not clear how the images from the CCD were converted to the tissue
optical properties. The procedure has to be presented.
3. The discussion section merely describes the data presented in the figures. The
authors also repeat the same few sentences when they present results for the
various parameters, simply changing the numerical values where necessary.
This makes the section long and difficult to read. Thus, this section cannot be
accepted as discussion.
4. The language of the paper should be improved, for there are some
imperfections concerning grammar and style.
Level of interest: An article of limited interest
Quality of written English: Needs some language corrections before being
published
Statistical review: Yes, but I do not feel adequately qualified to assess the
statistics.
Declaration of competing interests:
I declare that I have no competing interests
assistant