Title: Analysis of the distribution characteristics of pathogenic bacteria in the wound tissue of
patients with perianal abscess combined with infection and the influencing factors of wound
healing
Version: 3 Date: 20 Jan 2025
Reviewer:  Payam Behzadi
Reviewer's report:
Dear Author
Unfortunately, there are many cases which have not been revised.
1. The application of the terms should be unified: e.g., Gram-negative or
gram-negative not Gram-negative and gram-negative. There are several terms that
have been used the same throughout the manuscript. Please do revise all of them.
2. In abstract section: The authors have claimed "The results of multifactorial logistic
regression analysis showed that body mass index, diabetes mellitus, concurrent infections and
stool traits were independent risk factors influencing the poor quality of
wound healing (P < 0.05)." What does P < 0.05 mean?
Dear author, please do add in brief to the abstract.
3.  The keywords should be revised according to the MeSH terms. Please do revise
them.
4. The Methodology section still suffers from the lack of effective references. Please do  add
the related references for the used protocols.
5. Table 1 can be very effective if the current data presented by other items like
gender and the age range of the patients.
6.  Figure 1 can be very effective if the current data presented by other items like
gender and the age range of the patients. Please do read the following paper which can
be very useful reference for the current manuscript:
Distribution of chaperone-usher fimbriae and curli fimbriae among uropathogenic
Escherichia coli. BMC Microbiol. 2024 Sep 14;24(1):344. doi:
10.1186/s12866-024-03472-5. PMID: 39271999; PMCID: PMC11401301.
7. Please do interpret the results of the statistical analyses in Discussion section, in
details.
8. Discussion section has not been deeply revised.
9. Please do highlight the revised sections with yellow color.
Title: Analysis of the distribution characteristics of pathogenic bacteria in the wound tissue of
patients with perianal abscess combined with infection and the influencing factors of wound
healing
Version: 3 Date: 20 Jan 2025
Reviewer:  Payam Behzadi
Reviewer's report:
Dear Author
Unfortunately, there are many cases which have not been revised.
1. The application of the terms should be unified: e.g., Gram-negative or
gram-negative not Gram-negative and gram-negative. There are several terms that
have been used the same throughout the manuscript. Please do revise all of them.
2. In abstract section: The authors have claimed "The results of multifactorial logistic
regression analysis showed that body mass index, diabetes mellitus, concurrent infections and
stool traits were independent risk factors influencing the poor quality of
wound healing (P < 0.05)." What does P < 0.05 mean?
Dear author, please do add in brief to the abstract.
3.  The keywords should be revised according to the MeSH terms. Please do revise
them.
4. The Methodology section still suffers from the lack of effective references. Please do  add
the related references for the used protocols.
5. Table 1 can be very effective if the current data presented by other items like
gender and the age range of the patients.
6.  Figure 1 can be very effective if the current data presented by other items like
gender and the age range of the patients. Please do read the following paper which can
be very useful reference for the current manuscript:
Distribution of chaperone-usher fimbriae and curli fimbriae among uropathogenic
Escherichia coli. BMC Microbiol. 2024 Sep 14;24(1):344. doi:
10.1186/s12866-024-03472-5. PMID: 39271999; PMCID: PMC11401301.
7. Please do interpret the results of the statistical analyses in Discussion section, in
details.
8. Discussion section has not been deeply revised.
9. Please do highlight the revised sections with yellow color.
Please review this paper.
user
Title: Analysis of the distribution characteristics of pathogenic bacteria in the wound tissue of
patients with perianal abscess combined with infection and the influencing factors of wound
healing
Version: 3 Date: 20 Jan 2025
Reviewer:  Payam Behzadi
Reviewer's report:
Dear Author
Unfortunately, there are many cases which have not been revised.
1. The application of the terms should be unified: e.g., Gram-negative or
gram-negative not Gram-negative and gram-negative. There are several terms that
have been used the same throughout the manuscript. Please do revise all of them.
2. In abstract section: The authors have claimed "The results of multifactorial logistic
regression analysis showed that body mass index, diabetes mellitus, concurrent infections and
stool traits were independent risk factors influencing the poor quality of
wound healing (P < 0.05)." What does P < 0.05 mean?
Dear author, please do add in brief to the abstract.
3.  The keywords should be revised according to the MeSH terms. Please do revise
them.
4. The Methodology section still suffers from the lack of effective references. Please do  add
the related references for the used protocols.
5. Table 1 can be very effective if the current data presented by other items like
gender and the age range of the patients.
6.  Figure 1 can be very effective if the current data presented by other items like
gender and the age range of the patients. Please do read the following paper which can
be very useful reference for the current manuscript:
Distribution of chaperone-usher fimbriae and curli fimbriae among uropathogenic
Escherichia coli. BMC Microbiol. 2024 Sep 14;24(1):344. doi:
10.1186/s12866-024-03472-5. PMID: 39271999; PMCID: PMC11401301.
7. Please do interpret the results of the statistical analyses in Discussion section, in
details.
8. Discussion section has not been deeply revised.
9. Please do highlight the revised sections with yellow color.
assistant