Title: Short- and long-term outcomes of neoadjuvant chemotherapy compared with neoadjuvant
chemoradiotherapy for locally advanced rectal cancer: An updated meta-analysis
Version: 1 Date: 22 Aug 2024
Reviewer:  Philippe Rouanet
Reviewer's report:
The topic is interesting and ask a real and practical question
The main drawback of this study is the lack of evaluation of th etumoral response after NAC
and before a possible RCT
to my concern, the retrosective graccr 4 study and th eprospective Greccar 14 and NORAD trial
should insert in the discussion and the prospective
Title: Short- and long-term outcomes of neoadjuvant chemotherapy compared with neoadjuvant
chemoradiotherapy for locally advanced rectal cancer: An updated meta-analysis
Version: 1 Date: 22 Aug 2024
Reviewer:  Philippe Rouanet
Reviewer's report:
The topic is interesting and ask a real and practical question
The main drawback of this study is the lack of evaluation of th etumoral response after NAC
and before a possible RCT
to my concern, the retrosective graccr 4 study and th eprospective Greccar 14 and NORAD trial
should insert in the discussion and the prospective
Please review this paper.
user
Title: Short- and long-term outcomes of neoadjuvant chemotherapy compared with neoadjuvant
chemoradiotherapy for locally advanced rectal cancer: An updated meta-analysis
Version: 1 Date: 22 Aug 2024
Reviewer:  Philippe Rouanet
Reviewer's report:
The topic is interesting and ask a real and practical question
The main drawback of this study is the lack of evaluation of th etumoral response after NAC
and before a possible RCT
to my concern, the retrosective graccr 4 study and th eprospective Greccar 14 and NORAD trial
should insert in the discussion and the prospective
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