Title: Abnormal Platelet Parameters in Inflammatory Bowel Disease: A Systematic Review and
Meta-Analysis
Version: 1 Date: 05 Apr 2024
Reviewer's report:
The authors shared their work entitled "Abnormal Platelet Parameters in Inflammatory Bowel
Disease: A Systematic Review and Meta-Analysis".
The study is robust. There are however some issues I would like the authors to clarify:
1.  in your inclusion criteria, what was the definition of adults, did all studies have patients ages
18 and more? or was it different cut offs of adults?
2. The authors assessed for heterogeneity and yet used random-effects model irrespective of
heterogeneity.  Can they explain why?
3. the authors had no restrictions on the languages, was any translation services/help used during
the screening process? Should they be included or mentioned in the acknowledgements?
4. The authors included subgroups for region ie asia europe etc, but failed to explain why they
did so in the methods and  the results obtained in the discussions. The results cannot be linked
with racial or ethnic differences as those areas cover a vast range.
Title: Abnormal Platelet Parameters in Inflammatory Bowel Disease: A Systematic Review and
Meta-Analysis
Version: 1 Date: 05 Apr 2024
Reviewer's report:
The authors shared their work entitled "Abnormal Platelet Parameters in Inflammatory Bowel
Disease: A Systematic Review and Meta-Analysis".
The study is robust. There are however some issues I would like the authors to clarify:
1.  in your inclusion criteria, what was the definition of adults, did all studies have patients ages
18 and more? or was it different cut offs of adults?
2. The authors assessed for heterogeneity and yet used random-effects model irrespective of
heterogeneity.  Can they explain why?
3. the authors had no restrictions on the languages, was any translation services/help used during
the screening process? Should they be included or mentioned in the acknowledgements?
4. The authors included subgroups for region ie asia europe etc, but failed to explain why they
did so in the methods and  the results obtained in the discussions. The results cannot be linked
with racial or ethnic differences as those areas cover a vast range.
Please review this paper.
user
Title: Abnormal Platelet Parameters in Inflammatory Bowel Disease: A Systematic Review and
Meta-Analysis
Version: 1 Date: 05 Apr 2024
Reviewer's report:
The authors shared their work entitled "Abnormal Platelet Parameters in Inflammatory Bowel
Disease: A Systematic Review and Meta-Analysis".
The study is robust. There are however some issues I would like the authors to clarify:
1.  in your inclusion criteria, what was the definition of adults, did all studies have patients ages
18 and more? or was it different cut offs of adults?
2. The authors assessed for heterogeneity and yet used random-effects model irrespective of
heterogeneity.  Can they explain why?
3. the authors had no restrictions on the languages, was any translation services/help used during
the screening process? Should they be included or mentioned in the acknowledgements?
4. The authors included subgroups for region ie asia europe etc, but failed to explain why they
did so in the methods and  the results obtained in the discussions. The results cannot be linked
with racial or ethnic differences as those areas cover a vast range.
assistant