Title: Comparison of conventional MRI analysis versus MRI-based radiomics to predict the
circumferential margin resection involvement of rectal cancer
Version: 3 Date: 06 Mar 2024
Reviewer:  Pablo Palma
Reviewer's report:
The article has undoubtedly improved, especially as far as my revisions regarding clinical
involvement are concerned.
However, I miss the clarifications regarding other issues already indicated: The cohort of patients
included raises a number of important questions:
1. How can there be such a high number of patients with circumferential margin involvement
where no neoadjuvant treatment has been applied?
2. It would be very interesting if the authors could comment on the value of this
research in patients after neoadjuvant treatment, as a re-staging of their rectal
cancer.
Title: Comparison of conventional MRI analysis versus MRI-based radiomics to predict the
circumferential margin resection involvement of rectal cancer
Version: 3 Date: 06 Mar 2024
Reviewer:  Pablo Palma
Reviewer's report:
The article has undoubtedly improved, especially as far as my revisions regarding clinical
involvement are concerned.
However, I miss the clarifications regarding other issues already indicated: The cohort of patients
included raises a number of important questions:
1. How can there be such a high number of patients with circumferential margin involvement
where no neoadjuvant treatment has been applied?
2. It would be very interesting if the authors could comment on the value of this
research in patients after neoadjuvant treatment, as a re-staging of their rectal
cancer.
Please review this paper.
user
Title: Comparison of conventional MRI analysis versus MRI-based radiomics to predict the
circumferential margin resection involvement of rectal cancer
Version: 3 Date: 06 Mar 2024
Reviewer:  Pablo Palma
Reviewer's report:
The article has undoubtedly improved, especially as far as my revisions regarding clinical
involvement are concerned.
However, I miss the clarifications regarding other issues already indicated: The cohort of patients
included raises a number of important questions:
1. How can there be such a high number of patients with circumferential margin involvement
where no neoadjuvant treatment has been applied?
2. It would be very interesting if the authors could comment on the value of this
research in patients after neoadjuvant treatment, as a re-staging of their rectal
cancer.
assistant