Title: Fatigue in Patients with Inflammatory Bowel Disease - Strongly Influenced by Depression
and not Identifiable through Laboratory Testing: a Cross-Sectional Survey Study
Version: 1 Date: 01 Jun 2023
Reviewer's report:
I would like congratulate the authors for addressing a crucial aspect of Inflammatory Bowel
Disease (IBD) management, namely, fatigue. Their study focuses on a topic that is often
overlooked but significantly impacts the overall well-being of individuals with IBD. By
examining the relationship between fatigue and IBD, the authors have made a valuable
contribution to the field.
However, I have a few suggestions and questions regarding certain aspects of the study that I
believe could enhance the overall quality and impact of the research:
Sample Representation: I would appreciate it if the authors could explain why CD patients were
more than UC in the study and whether the sample accurately represents the larger population
of IBD patients.
Prospective Data: The authors mention that the data used in this study is from 2018. While
I understand that gathering prospective data can be challenging, it would be helpful if the
authors clarify the date of ethics approval and also if the same data has been used for any other
publication
Patient Selection: The study appears to include only patients who underwent outpatient (OP)
treatment. It would be valuable to acknowledge any limitations associated with this patient
selection criterion, as it may impact the generalizability of the findings to the entire IBD patient
population
Table Terminology: In the tables presented, it would be more appropriate to use the term "Total"
instead of "Together." This modification would enhance clarity and align with standard scientific
terminology.
UC Patients: The authors state that there was no influence of activity on fatigue among UC
patients. It would be beneficial to explore and discuss the potential reasons behind this finding.
Treatment Effects: Was there any specific impact of particular drugs or treatment on fatigue
Overall, this study contributes to the existing literature on IBD by shedding light on the often
neglected issue of fatigue. With the suggested refinements and elaborations, the authors can
enhance the impact of their research and provide valuable insights for clinicians, researchers,
and patients in the field of gastroenterology.
Title: Fatigue in Patients with Inflammatory Bowel Disease - Strongly Influenced by Depression
and not Identifiable through Laboratory Testing: a Cross-Sectional Survey Study
Version: 1 Date: 01 Jun 2023
Reviewer's report:
I would like congratulate the authors for addressing a crucial aspect of Inflammatory Bowel
Disease (IBD) management, namely, fatigue. Their study focuses on a topic that is often
overlooked but significantly impacts the overall well-being of individuals with IBD. By
examining the relationship between fatigue and IBD, the authors have made a valuable
contribution to the field.
However, I have a few suggestions and questions regarding certain aspects of the study that I
believe could enhance the overall quality and impact of the research:
Sample Representation: I would appreciate it if the authors could explain why CD patients were
more than UC in the study and whether the sample accurately represents the larger population
of IBD patients.
Prospective Data: The authors mention that the data used in this study is from 2018. While
I understand that gathering prospective data can be challenging, it would be helpful if the
authors clarify the date of ethics approval and also if the same data has been used for any other
publication
Patient Selection: The study appears to include only patients who underwent outpatient (OP)
treatment. It would be valuable to acknowledge any limitations associated with this patient
selection criterion, as it may impact the generalizability of the findings to the entire IBD patient
population
Table Terminology: In the tables presented, it would be more appropriate to use the term "Total"
instead of "Together." This modification would enhance clarity and align with standard scientific
terminology.
UC Patients: The authors state that there was no influence of activity on fatigue among UC
patients. It would be beneficial to explore and discuss the potential reasons behind this finding.
Treatment Effects: Was there any specific impact of particular drugs or treatment on fatigue
Overall, this study contributes to the existing literature on IBD by shedding light on the often
neglected issue of fatigue. With the suggested refinements and elaborations, the authors can
enhance the impact of their research and provide valuable insights for clinicians, researchers,
and patients in the field of gastroenterology.
Please review this paper.
user
Title: Fatigue in Patients with Inflammatory Bowel Disease - Strongly Influenced by Depression
and not Identifiable through Laboratory Testing: a Cross-Sectional Survey Study
Version: 1 Date: 01 Jun 2023
Reviewer's report:
I would like congratulate the authors for addressing a crucial aspect of Inflammatory Bowel
Disease (IBD) management, namely, fatigue. Their study focuses on a topic that is often
overlooked but significantly impacts the overall well-being of individuals with IBD. By
examining the relationship between fatigue and IBD, the authors have made a valuable
contribution to the field.
However, I have a few suggestions and questions regarding certain aspects of the study that I
believe could enhance the overall quality and impact of the research:
Sample Representation: I would appreciate it if the authors could explain why CD patients were
more than UC in the study and whether the sample accurately represents the larger population
of IBD patients.
Prospective Data: The authors mention that the data used in this study is from 2018. While
I understand that gathering prospective data can be challenging, it would be helpful if the
authors clarify the date of ethics approval and also if the same data has been used for any other
publication
Patient Selection: The study appears to include only patients who underwent outpatient (OP)
treatment. It would be valuable to acknowledge any limitations associated with this patient
selection criterion, as it may impact the generalizability of the findings to the entire IBD patient
population
Table Terminology: In the tables presented, it would be more appropriate to use the term "Total"
instead of "Together." This modification would enhance clarity and align with standard scientific
terminology.
UC Patients: The authors state that there was no influence of activity on fatigue among UC
patients. It would be beneficial to explore and discuss the potential reasons behind this finding.
Treatment Effects: Was there any specific impact of particular drugs or treatment on fatigue
Overall, this study contributes to the existing literature on IBD by shedding light on the often
neglected issue of fatigue. With the suggested refinements and elaborations, the authors can
enhance the impact of their research and provide valuable insights for clinicians, researchers,
and patients in the field of gastroenterology.
assistant