Title: Lipid Levels and Insulin Resistance Markers in Gastric Cancer Patients: Diagnostic and
Prognostic Significance
Version: 2 Date: 22 Aug 2024
Reviewer's report:
Lipid Levels and Insulin Resistance Markers in Gastric Cancer Patients: Diagnostic and
Prognostic Significance
In this study to investigate the clinical significance of serum lipid profiles, insulin resistance
markers including the triglyceride-glucose (TyG) index and the atherosclerotic index (AI), in
GC patients. Preoperative lipid profiles in the serum show a strong correlation with patients
diagnosed with GC. Evaluating a combination of various serum lipids and cancer markers
significantly improves diagnostic precision for GC and the ability to predict chemotherapy side
effects. Overall, this manuscript is well designed and studied. Some suggestions for this paper
are as follows:
Detailed comments to the author
1. The limitations of the paper and its interpretation are not discussed by using serum lipid
profiles, insulin resistance markers including the triglyceride-glucose (TyG) index and the
atherosclerotic index (AI), database collections.
2. In the discussion part, the author could discuss the possibility mechanism of chemotherapy
side effects.
Title: Lipid Levels and Insulin Resistance Markers in Gastric Cancer Patients: Diagnostic and
Prognostic Significance
Version: 2 Date: 22 Aug 2024
Reviewer's report:
Lipid Levels and Insulin Resistance Markers in Gastric Cancer Patients: Diagnostic and
Prognostic Significance
In this study to investigate the clinical significance of serum lipid profiles, insulin resistance
markers including the triglyceride-glucose (TyG) index and the atherosclerotic index (AI), in
GC patients. Preoperative lipid profiles in the serum show a strong correlation with patients
diagnosed with GC. Evaluating a combination of various serum lipids and cancer markers
significantly improves diagnostic precision for GC and the ability to predict chemotherapy side
effects. Overall, this manuscript is well designed and studied. Some suggestions for this paper
are as follows:
Detailed comments to the author
1. The limitations of the paper and its interpretation are not discussed by using serum lipid
profiles, insulin resistance markers including the triglyceride-glucose (TyG) index and the
atherosclerotic index (AI), database collections.
2. In the discussion part, the author could discuss the possibility mechanism of chemotherapy
side effects.
Please review this paper.
user
Title: Lipid Levels and Insulin Resistance Markers in Gastric Cancer Patients: Diagnostic and
Prognostic Significance
Version: 2 Date: 22 Aug 2024
Reviewer's report:
Lipid Levels and Insulin Resistance Markers in Gastric Cancer Patients: Diagnostic and
Prognostic Significance
In this study to investigate the clinical significance of serum lipid profiles, insulin resistance
markers including the triglyceride-glucose (TyG) index and the atherosclerotic index (AI), in
GC patients. Preoperative lipid profiles in the serum show a strong correlation with patients
diagnosed with GC. Evaluating a combination of various serum lipids and cancer markers
significantly improves diagnostic precision for GC and the ability to predict chemotherapy side
effects. Overall, this manuscript is well designed and studied. Some suggestions for this paper
are as follows:
Detailed comments to the author
1. The limitations of the paper and its interpretation are not discussed by using serum lipid
profiles, insulin resistance markers including the triglyceride-glucose (TyG) index and the
atherosclerotic index (AI), database collections.
2. In the discussion part, the author could discuss the possibility mechanism of chemotherapy
side effects.
assistant