Reviewer's report 
 A comparison of oral omeprazole and intravenous cimetidine in reducing complications of Title: 
duodenal peptic ulcer 
 3  11 October 2005 Version: Date: 
 Xavier Calvet Reviewer: 
Reviewer's report: 
General 
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Major Compulsory Revisions (that the author must respond to before a decision on publication can 
be reached) 
1. There is an aparent contradiction between the material and methods where the authoprs state 
that patients bleeding because of drugs were excluded and cite specifically NSAIDs and table 1 
showing that near 50% of the patients were on NSAID therapy. 
2. As far as I know, PPI's decrease acid secretion but not parietal cell mass. I suppose there has 
been an error in the redaction of the first paragraph of the discussion. 
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Minor Essential Revisions (such as missing labels on figures, or the wrong use of a term, which the 
author can be trusted to correct) 
------------------------------------------------------------------------------- 
Discretionary Revisions (which the author can choose to ignore) 
 Accept after minor essential revisions What next?: 
 An article of limited interest Level of interest: 
 Needs some language corrections before being published Quality of written English: 
 No Statistical review: 
Declaration of competing interests: 
'I declare that I have no competing interests' 
Reviewer's report 
 A comparison of oral omeprazole and intravenous cimetidine in reducing complications of Title: 
duodenal peptic ulcer 
 3  11 October 2005 Version: Date: 
 Xavier Calvet Reviewer: 
Reviewer's report: 
General 
------------------------------------------------------------------------------- 
Major Compulsory Revisions (that the author must respond to before a decision on publication can 
be reached) 
1. There is an aparent contradiction between the material and methods where the authoprs state 
that patients bleeding because of drugs were excluded and cite specifically NSAIDs and table 1 
showing that near 50% of the patients were on NSAID therapy. 
2. As far as I know, PPI's decrease acid secretion but not parietal cell mass. I suppose there has 
been an error in the redaction of the first paragraph of the discussion. 
------------------------------------------------------------------------------- 
Minor Essential Revisions (such as missing labels on figures, or the wrong use of a term, which the 
author can be trusted to correct) 
------------------------------------------------------------------------------- 
Discretionary Revisions (which the author can choose to ignore) 
 Accept after minor essential revisions What next?: 
 An article of limited interest Level of interest: 
 Needs some language corrections before being published Quality of written English: 
 No Statistical review: 
Declaration of competing interests: 
'I declare that I have no competing interests' 
Please review this paper.
user
Reviewer's report 
 A comparison of oral omeprazole and intravenous cimetidine in reducing complications of Title: 
duodenal peptic ulcer 
 3  11 October 2005 Version: Date: 
 Xavier Calvet Reviewer: 
Reviewer's report: 
General 
------------------------------------------------------------------------------- 
Major Compulsory Revisions (that the author must respond to before a decision on publication can 
be reached) 
1. There is an aparent contradiction between the material and methods where the authoprs state 
that patients bleeding because of drugs were excluded and cite specifically NSAIDs and table 1 
showing that near 50% of the patients were on NSAID therapy. 
2. As far as I know, PPI's decrease acid secretion but not parietal cell mass. I suppose there has 
been an error in the redaction of the first paragraph of the discussion. 
------------------------------------------------------------------------------- 
Minor Essential Revisions (such as missing labels on figures, or the wrong use of a term, which the 
author can be trusted to correct) 
------------------------------------------------------------------------------- 
Discretionary Revisions (which the author can choose to ignore) 
 Accept after minor essential revisions What next?: 
 An article of limited interest Level of interest: 
 Needs some language corrections before being published Quality of written English: 
 No Statistical review: 
Declaration of competing interests: 
'I declare that I have no competing interests' 
assistant