Reviewer's report
Title:An association between colonic adenoma and abdominal obesity : A cross
sectional study.
Version: 5Date:19 November 2008
Reviewer: Anette Hjartåker
Reviewer's report:
The manuscript has improved a lot after the revision. Unfortunately the abstract
is missing in the version I have access to, so I cannot comment on that.
I have some minor comments:
Introduction:
1. Please include a statement regarding the association between BMI and
adenoma.
2. Also, I suggest referring to the latest report from WCRF/AICR, 2007.
3. The 1st paragraph is a mix of issues regarding colorectal cancer in particular
and cancer in general. I suggest restricting the presentation to colorectal issues.
4. First sentence in 2nd paragraph: exchange “… the opportunity.. ” to “an
opportunity..”
Methods:
5. Please give some more details about the dietary assessment method used. A
food frequency questionnaire is usually used to record habitually diet during the
last year, month etc, i.e. giving retrospective data.
6. The BMI category 23.0-25.0 and the BMI category # 25 are overlapping.
Please correct.
7. The 2nd sentence in the 3rd paragraph (starting with “We excluded…”) needs
to be rewritten.
Results:
8. As you did analyze abdominal obesity according to number of polyps, I think
you should mention this in the result section even if you did not find any
statistically significant association. It is of interest to know that you found an
association between having/not having polyps and abdominal obesity, but that
you did not find an association between number of polyps and abdominal
obesity. This should also be commented on in the discussion.
9. In the 3rd and 4th sentence in the 3rd paragraph: Omit the exact numbers and
present only the percentages. n are in any case given in table 2.
Table 1:
10. Please add that the figures are age- and gender adjusted.
Table 2:
11. The absolute numbers (n) should be given in brackets instead of the
percentages. Total n for the abdominal group and total n for the normal group
could be included in their respective column headings (analogous to table 1).
Tables 3 and 4:
12. The wording “OR and “Adjusting OR” are misleading as also the first OR is
adjusted according to the footnote. Please rewrite, e.g. Adjusted OR, model 1
and adjusted OR model 2, + inclusion of correct reference to the footnotes.
13. Please include n for each category in the tables.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: Yes, and I have assessed the statistics in my report.
Declaration of competing interests:
I declare that I have no competing interests
Reviewer's report
Title:An association between colonic adenoma and abdominal obesity : A cross
sectional study.
Version: 5Date:19 November 2008
Reviewer: Anette Hjartåker
Reviewer's report:
The manuscript has improved a lot after the revision. Unfortunately the abstract
is missing in the version I have access to, so I cannot comment on that.
I have some minor comments:
Introduction:
1. Please include a statement regarding the association between BMI and
adenoma.
2. Also, I suggest referring to the latest report from WCRF/AICR, 2007.
3. The 1st paragraph is a mix of issues regarding colorectal cancer in particular
and cancer in general. I suggest restricting the presentation to colorectal issues.
4. First sentence in 2nd paragraph: exchange “… the opportunity.. ” to “an
opportunity..”
Methods:
5. Please give some more details about the dietary assessment method used. A
food frequency questionnaire is usually used to record habitually diet during the
last year, month etc, i.e. giving retrospective data.
6. The BMI category 23.0-25.0 and the BMI category # 25 are overlapping.
Please correct.
7. The 2nd sentence in the 3rd paragraph (starting with “We excluded…”) needs
to be rewritten.
Results:
8. As you did analyze abdominal obesity according to number of polyps, I think
you should mention this in the result section even if you did not find any
statistically significant association. It is of interest to know that you found an
association between having/not having polyps and abdominal obesity, but that
you did not find an association between number of polyps and abdominal
obesity. This should also be commented on in the discussion.
9. In the 3rd and 4th sentence in the 3rd paragraph: Omit the exact numbers and
present only the percentages. n are in any case given in table 2.
Table 1:
10. Please add that the figures are age- and gender adjusted.
Table 2:
11. The absolute numbers (n) should be given in brackets instead of the
percentages. Total n for the abdominal group and total n for the normal group
could be included in their respective column headings (analogous to table 1).
Tables 3 and 4:
12. The wording “OR and “Adjusting OR” are misleading as also the first OR is
adjusted according to the footnote. Please rewrite, e.g. Adjusted OR, model 1
and adjusted OR model 2, + inclusion of correct reference to the footnotes.
13. Please include n for each category in the tables.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: Yes, and I have assessed the statistics in my report.
Declaration of competing interests:
I declare that I have no competing interests
Please review this paper.
user
Reviewer's report
Title:An association between colonic adenoma and abdominal obesity : A cross
sectional study.
Version: 5Date:19 November 2008
Reviewer: Anette Hjartåker
Reviewer's report:
The manuscript has improved a lot after the revision. Unfortunately the abstract
is missing in the version I have access to, so I cannot comment on that.
I have some minor comments:
Introduction:
1. Please include a statement regarding the association between BMI and
adenoma.
2. Also, I suggest referring to the latest report from WCRF/AICR, 2007.
3. The 1st paragraph is a mix of issues regarding colorectal cancer in particular
and cancer in general. I suggest restricting the presentation to colorectal issues.
4. First sentence in 2nd paragraph: exchange “… the opportunity.. ” to “an
opportunity..”
Methods:
5. Please give some more details about the dietary assessment method used. A
food frequency questionnaire is usually used to record habitually diet during the
last year, month etc, i.e. giving retrospective data.
6. The BMI category 23.0-25.0 and the BMI category # 25 are overlapping.
Please correct.
7. The 2nd sentence in the 3rd paragraph (starting with “We excluded…”) needs
to be rewritten.
Results:
8. As you did analyze abdominal obesity according to number of polyps, I think
you should mention this in the result section even if you did not find any
statistically significant association. It is of interest to know that you found an
association between having/not having polyps and abdominal obesity, but that
you did not find an association between number of polyps and abdominal
obesity. This should also be commented on in the discussion.
9. In the 3rd and 4th sentence in the 3rd paragraph: Omit the exact numbers and
present only the percentages. n are in any case given in table 2.
Table 1:
10. Please add that the figures are age- and gender adjusted.
Table 2:
11. The absolute numbers (n) should be given in brackets instead of the
percentages. Total n for the abdominal group and total n for the normal group
could be included in their respective column headings (analogous to table 1).
Tables 3 and 4:
12. The wording “OR and “Adjusting OR” are misleading as also the first OR is
adjusted according to the footnote. Please rewrite, e.g. Adjusted OR, model 1
and adjusted OR model 2, + inclusion of correct reference to the footnotes.
13. Please include n for each category in the tables.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: Yes, and I have assessed the statistics in my report.
Declaration of competing interests:
I declare that I have no competing interests
assistant