Reviewer's report
Title:Correlation between magnifying narrow band imaging and histopathology
in gastric protruding/ or polypoid lesions: a pilot feasibility trial
Version: 1Date:11 August 2011
Reviewer: Hsiu-Po Wang
Reviewer's report:
Comments to the authors:
In this study, authors have investigated the usefulness of magnifying endoscopy
with narrow band imaging (ME-NBI) system in the evaluation of gastric polypoid
lesions. Although few studies have addressed this issue, however, there are
some questions that need considerations.
1) The classifications of gastric lesions by ME-NBI have been studied by several
investigators previously, such as Yao et al, Nakayoshi et al, Goto et al, Kaise et
al, etc.; however, the clinical implication is still limited due to complicated
classification system. In this study, by using four “fine mucosal structures” and
five “micro vascular patterns”, there will be “20” combined patterns for
interpretations. Therefore, the complexity hampered the clinical usefulness of this
study.
2) Because the interpretation of ME-NBI imaging is subjective if the classification
is complicated, the variations of endoscopist’s opinions may exist. Although the
endoscopic diagnoses of this study were confirmed by consensus with the
members, there were no “inter-observer” or “intra-observer” evaluation for the
classification system.
3) In this study, because not all the polypoid lesions were removed in en-bloc
pattern (some of them ,especially for endoscopic suspicious non-neoplastic
lesions, were biopsied for pathological examination), bias exist for the
histopathological results of the polypoid lesions.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests
Reviewer's report
Title:Correlation between magnifying narrow band imaging and histopathology
in gastric protruding/ or polypoid lesions: a pilot feasibility trial
Version: 1Date:11 August 2011
Reviewer: Hsiu-Po Wang
Reviewer's report:
Comments to the authors:
In this study, authors have investigated the usefulness of magnifying endoscopy
with narrow band imaging (ME-NBI) system in the evaluation of gastric polypoid
lesions. Although few studies have addressed this issue, however, there are
some questions that need considerations.
1) The classifications of gastric lesions by ME-NBI have been studied by several
investigators previously, such as Yao et al, Nakayoshi et al, Goto et al, Kaise et
al, etc.; however, the clinical implication is still limited due to complicated
classification system. In this study, by using four “fine mucosal structures” and
five “micro vascular patterns”, there will be “20” combined patterns for
interpretations. Therefore, the complexity hampered the clinical usefulness of this
study.
2) Because the interpretation of ME-NBI imaging is subjective if the classification
is complicated, the variations of endoscopist’s opinions may exist. Although the
endoscopic diagnoses of this study were confirmed by consensus with the
members, there were no “inter-observer” or “intra-observer” evaluation for the
classification system.
3) In this study, because not all the polypoid lesions were removed in en-bloc
pattern (some of them ,especially for endoscopic suspicious non-neoplastic
lesions, were biopsied for pathological examination), bias exist for the
histopathological results of the polypoid lesions.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests
Please review this paper.
user
Reviewer's report
Title:Correlation between magnifying narrow band imaging and histopathology
in gastric protruding/ or polypoid lesions: a pilot feasibility trial
Version: 1Date:11 August 2011
Reviewer: Hsiu-Po Wang
Reviewer's report:
Comments to the authors:
In this study, authors have investigated the usefulness of magnifying endoscopy
with narrow band imaging (ME-NBI) system in the evaluation of gastric polypoid
lesions. Although few studies have addressed this issue, however, there are
some questions that need considerations.
1) The classifications of gastric lesions by ME-NBI have been studied by several
investigators previously, such as Yao et al, Nakayoshi et al, Goto et al, Kaise et
al, etc.; however, the clinical implication is still limited due to complicated
classification system. In this study, by using four “fine mucosal structures” and
five “micro vascular patterns”, there will be “20” combined patterns for
interpretations. Therefore, the complexity hampered the clinical usefulness of this
study.
2) Because the interpretation of ME-NBI imaging is subjective if the classification
is complicated, the variations of endoscopist’s opinions may exist. Although the
endoscopic diagnoses of this study were confirmed by consensus with the
members, there were no “inter-observer” or “intra-observer” evaluation for the
classification system.
3) In this study, because not all the polypoid lesions were removed in en-bloc
pattern (some of them ,especially for endoscopic suspicious non-neoplastic
lesions, were biopsied for pathological examination), bias exist for the
histopathological results of the polypoid lesions.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests
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