Title: Novel non-HDLc/HDLc Ratio for Predicting MASLD: A Cross-Sectional Study in a
Chinese Health Screening Population
Version: 2 Date: 27 Sep 2024
Reviewer:  Panagiotis Tsibouris
Reviewer's report:
MAFLD should better used Minimal adaption is needed to accomplish the change Definition
should be provided in the introduction Dyslipidemia is part of the metabic syndrome Authors
should refer to possibility of patients with dyslipidemia  ( pathological cholesterol, HDL, TG)
to be connected with MAFLD They should also report possible role of non-HDL cholesterol in
the pathogenesis of MASLD/MASH Methods Number of excluded cases belong to the results
Drug induced liver injury needs rechalenge Authors should define if they exclude cases with
verified vases of toxic liver injury or even possible cases Chronic lever diseases should be
reported in detail. Patients ith MAFLD and MeLD should be reported separately if possible
Commorbidities precludeing exclusion from the study population should be described in detail
(CKD, Hematological disorders) Was any patient with heart disease excluded? Results Actually
authors defined as NAFLD exessive presence of fat in the liver Calculations should be redone
for MASLD Thats fatty liver +metabolic syndrome
Title: Novel non-HDLc/HDLc Ratio for Predicting MASLD: A Cross-Sectional Study in a
Chinese Health Screening Population
Version: 2 Date: 27 Sep 2024
Reviewer:  Panagiotis Tsibouris
Reviewer's report:
MAFLD should better used Minimal adaption is needed to accomplish the change Definition
should be provided in the introduction Dyslipidemia is part of the metabic syndrome Authors
should refer to possibility of patients with dyslipidemia  ( pathological cholesterol, HDL, TG)
to be connected with MAFLD They should also report possible role of non-HDL cholesterol in
the pathogenesis of MASLD/MASH Methods Number of excluded cases belong to the results
Drug induced liver injury needs rechalenge Authors should define if they exclude cases with
verified vases of toxic liver injury or even possible cases Chronic lever diseases should be
reported in detail. Patients ith MAFLD and MeLD should be reported separately if possible
Commorbidities precludeing exclusion from the study population should be described in detail
(CKD, Hematological disorders) Was any patient with heart disease excluded? Results Actually
authors defined as NAFLD exessive presence of fat in the liver Calculations should be redone
for MASLD Thats fatty liver +metabolic syndrome
Please review this paper.
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Title: Novel non-HDLc/HDLc Ratio for Predicting MASLD: A Cross-Sectional Study in a
Chinese Health Screening Population
Version: 2 Date: 27 Sep 2024
Reviewer:  Panagiotis Tsibouris
Reviewer's report:
MAFLD should better used Minimal adaption is needed to accomplish the change Definition
should be provided in the introduction Dyslipidemia is part of the metabic syndrome Authors
should refer to possibility of patients with dyslipidemia  ( pathological cholesterol, HDL, TG)
to be connected with MAFLD They should also report possible role of non-HDL cholesterol in
the pathogenesis of MASLD/MASH Methods Number of excluded cases belong to the results
Drug induced liver injury needs rechalenge Authors should define if they exclude cases with
verified vases of toxic liver injury or even possible cases Chronic lever diseases should be
reported in detail. Patients ith MAFLD and MeLD should be reported separately if possible
Commorbidities precludeing exclusion from the study population should be described in detail
(CKD, Hematological disorders) Was any patient with heart disease excluded? Results Actually
authors defined as NAFLD exessive presence of fat in the liver Calculations should be redone
for MASLD Thats fatty liver +metabolic syndrome
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