Title: The Association between Non- and Pro-Healthy Diet Indices and the Risk of Colorectal
Cancer: A Case-Control Study
Version: 0 Date: 30 Sep 2024
Reviewer's report:
Introduction
Comment 1: Please add the following new reference concerning
Iranian statistics https://gco.iarc.who.int/media/globocan/factsheets/populations/364-iran-
islamic-republic-of-fact-sheet.pdf
Comment 2: Lines 74 and 79: When describing the studies, the type of the study is needed (cross-
sectional, case-control, etc).
Comment 3: please add same references about epidemiological and nutritional transition in Iran
as a study justification.
Methods
Comment 4: Have you done any sensitive analysis to confirm the results?
Comment 5: Please specify the reference category in the statistical analysis (lowest or highest
tertile)
Comment 6: Were the tertile categories based on the control distribution or on the entire included
population?
Discussion
Comment 7: The role of inflammation in the development of CRC must be considered.
Comment 8: The link between gut microbiota and inflammation should also be explored.
Title: The Association between Non- and Pro-Healthy Diet Indices and the Risk of Colorectal
Cancer: A Case-Control Study
Version: 0 Date: 30 Sep 2024
Reviewer's report:
Introduction
Comment 1: Please add the following new reference concerning
Iranian statistics https://gco.iarc.who.int/media/globocan/factsheets/populations/364-iran-
islamic-republic-of-fact-sheet.pdf
Comment 2: Lines 74 and 79: When describing the studies, the type of the study is needed (cross-
sectional, case-control, etc).
Comment 3: please add same references about epidemiological and nutritional transition in Iran
as a study justification.
Methods
Comment 4: Have you done any sensitive analysis to confirm the results?
Comment 5: Please specify the reference category in the statistical analysis (lowest or highest
tertile)
Comment 6: Were the tertile categories based on the control distribution or on the entire included
population?
Discussion
Comment 7: The role of inflammation in the development of CRC must be considered.
Comment 8: The link between gut microbiota and inflammation should also be explored.
Please review this paper.
user
Title: The Association between Non- and Pro-Healthy Diet Indices and the Risk of Colorectal
Cancer: A Case-Control Study
Version: 0 Date: 30 Sep 2024
Reviewer's report:
Introduction
Comment 1: Please add the following new reference concerning
Iranian statistics https://gco.iarc.who.int/media/globocan/factsheets/populations/364-iran-
islamic-republic-of-fact-sheet.pdf
Comment 2: Lines 74 and 79: When describing the studies, the type of the study is needed (cross-
sectional, case-control, etc).
Comment 3: please add same references about epidemiological and nutritional transition in Iran
as a study justification.
Methods
Comment 4: Have you done any sensitive analysis to confirm the results?
Comment 5: Please specify the reference category in the statistical analysis (lowest or highest
tertile)
Comment 6: Were the tertile categories based on the control distribution or on the entire included
population?
Discussion
Comment 7: The role of inflammation in the development of CRC must be considered.
Comment 8: The link between gut microbiota and inflammation should also be explored.
assistant