Reviewer's report
Title:A case series in patients with enteropathy and chronic granulomatous
diseases
Version:2Date:4 March 2015
Reviewer: Heyson Chan
Reviewer's report:
The authors reported three cases with sarcoidosis and celiac-like enteropathy,
which has been rarely reported in the literature.
Major revision
Although this is of interest in the field of gastroenterology, there are several major
compulsory revisions that the authors need to address before publication.
As the authors had stated, sarcoidosis is a diagnosis of exclusion. It is therefore
important for them to explain how the other differential diagnoses were being
excluded. In patient A, it was stated that bronchial biopsies revealed no evidence
of mycobacteria. Please specify if it was by ZN stain or formal TB culture has
been performed. In patient B, please specify what had been done to exclude
other differential diagnoses. In patient C, again, please specify what had been
done for the bronchoscopy.
Treatment should also be discussed. In patient A, it was stated that the patient
received a course of prednisolone. Please specify the duration and dosage used.
Please also specify whether maintenance therapy was required to maintain
remission for the underlying sarcoidosis. In patient B, please specify what is
meant by several courses.
Minor essential revision
There is room for improvement for the quality of written English. Below are
examples that the authors may consider revising:
- Page 3, line 25: “studies suggest” instead of “studies suggests”
- Page 5, line 13: “at the age” instead of “at an age”
- Page 6, line 6: “several courses of steroid” instead of “several times steroid”
- Page 8, line 18: “Independent of” instead of “independently of”
- Page 20, line 10: “presented with” instead of “presented”
Discretionary revisions
The authors may consider adding a conclusion statement at the end of the main
text to highlight the significance of this case series.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
I declare that I have no competing interests
Reviewer's report
Title:A case series in patients with enteropathy and chronic granulomatous
diseases
Version:2Date:4 March 2015
Reviewer: Heyson Chan
Reviewer's report:
The authors reported three cases with sarcoidosis and celiac-like enteropathy,
which has been rarely reported in the literature.
Major revision
Although this is of interest in the field of gastroenterology, there are several major
compulsory revisions that the authors need to address before publication.
As the authors had stated, sarcoidosis is a diagnosis of exclusion. It is therefore
important for them to explain how the other differential diagnoses were being
excluded. In patient A, it was stated that bronchial biopsies revealed no evidence
of mycobacteria. Please specify if it was by ZN stain or formal TB culture has
been performed. In patient B, please specify what had been done to exclude
other differential diagnoses. In patient C, again, please specify what had been
done for the bronchoscopy.
Treatment should also be discussed. In patient A, it was stated that the patient
received a course of prednisolone. Please specify the duration and dosage used.
Please also specify whether maintenance therapy was required to maintain
remission for the underlying sarcoidosis. In patient B, please specify what is
meant by several courses.
Minor essential revision
There is room for improvement for the quality of written English. Below are
examples that the authors may consider revising:
- Page 3, line 25: “studies suggest” instead of “studies suggests”
- Page 5, line 13: “at the age” instead of “at an age”
- Page 6, line 6: “several courses of steroid” instead of “several times steroid”
- Page 8, line 18: “Independent of” instead of “independently of”
- Page 20, line 10: “presented with” instead of “presented”
Discretionary revisions
The authors may consider adding a conclusion statement at the end of the main
text to highlight the significance of this case series.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
I declare that I have no competing interests
Please review this paper.
user
Reviewer's report
Title:A case series in patients with enteropathy and chronic granulomatous
diseases
Version:2Date:4 March 2015
Reviewer: Heyson Chan
Reviewer's report:
The authors reported three cases with sarcoidosis and celiac-like enteropathy,
which has been rarely reported in the literature.
Major revision
Although this is of interest in the field of gastroenterology, there are several major
compulsory revisions that the authors need to address before publication.
As the authors had stated, sarcoidosis is a diagnosis of exclusion. It is therefore
important for them to explain how the other differential diagnoses were being
excluded. In patient A, it was stated that bronchial biopsies revealed no evidence
of mycobacteria. Please specify if it was by ZN stain or formal TB culture has
been performed. In patient B, please specify what had been done to exclude
other differential diagnoses. In patient C, again, please specify what had been
done for the bronchoscopy.
Treatment should also be discussed. In patient A, it was stated that the patient
received a course of prednisolone. Please specify the duration and dosage used.
Please also specify whether maintenance therapy was required to maintain
remission for the underlying sarcoidosis. In patient B, please specify what is
meant by several courses.
Minor essential revision
There is room for improvement for the quality of written English. Below are
examples that the authors may consider revising:
- Page 3, line 25: “studies suggest” instead of “studies suggests”
- Page 5, line 13: “at the age” instead of “at an age”
- Page 6, line 6: “several courses of steroid” instead of “several times steroid”
- Page 8, line 18: “Independent of” instead of “independently of”
- Page 20, line 10: “presented with” instead of “presented”
Discretionary revisions
The authors may consider adding a conclusion statement at the end of the main
text to highlight the significance of this case series.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
I declare that I have no competing interests
assistant