Title: Efficacy and safety of ERCP in patients with situs inversus totalis: multicenter case series
and literature review
Version: 3 Date: 05 Oct 2022
Reviewer's report:
This case series shows about ERCP in patients with SIT.
ERCP for patients with SIT is very rare condition, and the information from this case series is
important to do ERCP safely.
However, I have some concerns.
1. In the supine position, how is respiratory complications such as dysphagic pneumonia and
decrease of SpO2 during the procedure?
2. Why do you think is the rate of successful cannulation higher in modified positions than
in prone position? Is it because the biliary orifice is directed to 11 o’clock? Please state in
Discussion if possible.
Title: Efficacy and safety of ERCP in patients with situs inversus totalis: multicenter case series
and literature review
Version: 3 Date: 05 Oct 2022
Reviewer's report:
This case series shows about ERCP in patients with SIT.
ERCP for patients with SIT is very rare condition, and the information from this case series is
important to do ERCP safely.
However, I have some concerns.
1. In the supine position, how is respiratory complications such as dysphagic pneumonia and
decrease of SpO2 during the procedure?
2. Why do you think is the rate of successful cannulation higher in modified positions than
in prone position? Is it because the biliary orifice is directed to 11 o’clock? Please state in
Discussion if possible.
Please review this paper.
user
Title: Efficacy and safety of ERCP in patients with situs inversus totalis: multicenter case series
and literature review
Version: 3 Date: 05 Oct 2022
Reviewer's report:
This case series shows about ERCP in patients with SIT.
ERCP for patients with SIT is very rare condition, and the information from this case series is
important to do ERCP safely.
However, I have some concerns.
1. In the supine position, how is respiratory complications such as dysphagic pneumonia and
decrease of SpO2 during the procedure?
2. Why do you think is the rate of successful cannulation higher in modified positions than
in prone position? Is it because the biliary orifice is directed to 11 o’clock? Please state in
Discussion if possible.
assistant