Reviewer's report
Title:Concurrent association of inflammatory polymyositis and Crohn's ileo-colitis
in a male: A case report of a rare association and review of literature
Version:3Date:18 November 2013
Reviewer: Klaus Herrlinger
Reviewer's report:
I doubt the diagnosis of Crohn’s disease. First of all, the patient had never
reported signs of IBD before. Endoscopy and histology are not diagnostic but
could also be attributed to toxic, ischemic or infectious colitis. The first seems to
be realistic since the patient had had severe alcohol excess three days prior to
admission. Combined steroid and azathioprine therapy did not suffice to induce
remission but to authors’ opinion the addition of 5-ASA did. Since 5-ASA has
shown marginal if any efficacy in Crohn’s disease it is very unlikely that this
treatment has led to a complete clinical and endoscopical (!) remission of Crohn’s
disease.
Level of interest: An article of insufficient interest to warrant publication in a
scientific/medical journal
Quality of written English: Not suitable for publication unless extensively edited
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
no
Reviewer's report
Title:Concurrent association of inflammatory polymyositis and Crohn's ileo-colitis
in a male: A case report of a rare association and review of literature
Version:3Date:18 November 2013
Reviewer: Klaus Herrlinger
Reviewer's report:
I doubt the diagnosis of Crohn’s disease. First of all, the patient had never
reported signs of IBD before. Endoscopy and histology are not diagnostic but
could also be attributed to toxic, ischemic or infectious colitis. The first seems to
be realistic since the patient had had severe alcohol excess three days prior to
admission. Combined steroid and azathioprine therapy did not suffice to induce
remission but to authors’ opinion the addition of 5-ASA did. Since 5-ASA has
shown marginal if any efficacy in Crohn’s disease it is very unlikely that this
treatment has led to a complete clinical and endoscopical (!) remission of Crohn’s
disease.
Level of interest: An article of insufficient interest to warrant publication in a
scientific/medical journal
Quality of written English: Not suitable for publication unless extensively edited
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
no
Please review this paper.
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Reviewer's report
Title:Concurrent association of inflammatory polymyositis and Crohn's ileo-colitis
in a male: A case report of a rare association and review of literature
Version:3Date:18 November 2013
Reviewer: Klaus Herrlinger
Reviewer's report:
I doubt the diagnosis of Crohn’s disease. First of all, the patient had never
reported signs of IBD before. Endoscopy and histology are not diagnostic but
could also be attributed to toxic, ischemic or infectious colitis. The first seems to
be realistic since the patient had had severe alcohol excess three days prior to
admission. Combined steroid and azathioprine therapy did not suffice to induce
remission but to authors’ opinion the addition of 5-ASA did. Since 5-ASA has
shown marginal if any efficacy in Crohn’s disease it is very unlikely that this
treatment has led to a complete clinical and endoscopical (!) remission of Crohn’s
disease.
Level of interest: An article of insufficient interest to warrant publication in a
scientific/medical journal
Quality of written English: Not suitable for publication unless extensively edited
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
no
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