Reviewer ’s report  
 
Title: A case report of intestinal obstruction caused by cryptogenic multifocal ulcerous stenosing  
enteritis  
 
Version: 0 Date: 02 Jul 2020  
 
Reviewer's report:  
 
1. You should not introduce confusion of CMUSE and CNSU. If term CNSU is already given than 
you should try and use the same. An uncommon entity doesn 't deserve confusion in literature. So 
I suggest align and use term CNSU unless you believe that CNSU is a misnomer and ideal 
terminology should be CMUSE!  
2. Too many grammar and language revisions needed e.g. patient doesn't get admitted for surgical 
treatment of small bowel obstruction. Patient is admitted for symptoms of vomiting, pain etc and 
during investigations we find small bowel obstruction and hence we advocate surgical treatment 
based on some indications etc...… So your language of case presentat ion has to be refined.  
3. Conclusion - You should not write that you will continue to follow up for relapse of condition!. 
Conclusion is that clinicians should be aware of this rare or uncommon entity etc.... Raise 
awareness by reporting this entity. So ag ain, language needs to be refined please.  
4. Currently, there are only over 60 cases of CMUSE or CNSU reported in the world [1],Which  
was first reportedin 1964[2], It featured by unexplained small bowel multiple superficial 
ulcers,stenosis,obstruction and  no biological signs of systematic inflammation, which are prone to 
recurrence ，Some patients are effective in hormone therapy[3].  
Comment - The above is all incorrect grammar. Comma, fullstop, sentence formation all is wrong. 
Needs revision please.  
5. In t he future, we will continue to follow up this patient, and regularly perform barium meal 
examinations of the whole digestive tract, and if necessary, perform capsule endoscopy or 
enteroscopy to observe the intestinal cavity and observe whether similar lesi ons recur.  
Comment - All statements like above are not needed. You just need to state that you shall continue 
to followup the patient and monitor for relapse of the condition. Please don't speculate. There is 
no indication for 'regular barium enema'etc. an d Capsule is contraindicated (relative 
contraindication if not absolute) in patients with suspected obstruction or adhesions.  
6. Authors have used different font types e.g. NSAID is different font type. In Short, grammar, 
language etc needs extensive revi sion for worthy scientific manuscript. Case is novel. Case is good. 
But the whole presentation, style etc needs extensive revision of content.  
7. Remove figure 2 of ct scan and also remove one histology figure. You need to include 
magnification, stains and what does the histology figure show with some arrows inside image to 
tell readers what is seen. So total 2 figures will be removed and we will  have 4 - ct scan, operative 
picture x 2 and histology.  
Thanks  
 
Publons Reviewer Recognition . Springer Nature can send verifica tion of this review directly to 
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Please find the details of processing in Publons ’ privacy policy https://publons.com/about/terms  
 
Yes 
 
Are the m ethods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
Yes 
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
No 
 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in the manus cript or would you recommend an additional 
statistical review?  
If an additional statistical review is recommended, please speci fy what aspects require further 
assessment in your comments to the editors.  
 
Not relevant to this manuscript  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Not suitable for publication unless extensively edited  
 
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following questions:  
 
1. Have you in the past five years received reimbursements, fees, funding, or salary from an 
organisation that may in any way gain or lose financial ly from the publication of this 
manuscript, either now or in the future?  
 
2. Do you hold any stocks or shares in an organisation t hat may in any way gain or lose 
financially from the publication of t his manuscript, either now or in the future?  
 
3. Do you hold or are you currently applying for any patents  relating to the content of the 
manuscript?  
 
4. Have you received reimbursements, fees, funding, or salary from an organization that holds 
or has applie d for patents relating to the content of the manuscript?  
 
5. Do you have any other financial competing interests?  
 
6. Do you have any non -financial competing interests in relation to this paper?  
 
If you can answer no to all of the above, write 'I declare that  I have no competing interests' below.  
If your reply is yes to any, please give details below.  
 
I declare that I have no competing interests  
 
Reviewer Publication Consent. I agree for my report to be made available under an Open Access  
Creative Commons CC -BY License ( http://creativecommons.org/licenses/by/4.0 ) if this 
manuscript is accepted for publication. Any comments that I do not wish to be included in the 
published report have been included as confidential comments to the editor, wh ich will not be 
published.  If you are not happy for us to publish this report, please contact the edi torial office 
before completing the review.  If you wish, you can include your name in your publish ed report. 
Please note you must decide whether to include y our name at the start of the process and  confirm 
this decision whenever prompted. If you change your decision later, we will not be able to publish 
your name.  
 
I agree to the terms of the CC -BY 4.0 license; please do not publish my name with my report.  
(default) 
Reviewer ’s report  
 
Title: A case report of intestinal obstruction caused by cryptogenic multifocal ulcerous stenosing  
enteritis  
 
Version: 0 Date: 02 Jul 2020  
 
Reviewer's report:  
 
1. You should not introduce confusion of CMUSE and CNSU. If term CNSU is already given than 
you should try and use the same. An uncommon entity doesn 't deserve confusion in literature. So 
I suggest align and use term CNSU unless you believe that CNSU is a misnomer and ideal 
terminology should be CMUSE!  
2. Too many grammar and language revisions needed e.g. patient doesn't get admitted for surgical 
treatment of small bowel obstruction. Patient is admitted for symptoms of vomiting, pain etc and 
during investigations we find small bowel obstruction and hence we advocate surgical treatment 
based on some indications etc...… So your language of case presentat ion has to be refined.  
3. Conclusion - You should not write that you will continue to follow up for relapse of condition!. 
Conclusion is that clinicians should be aware of this rare or uncommon entity etc.... Raise 
awareness by reporting this entity. So ag ain, language needs to be refined please.  
4. Currently, there are only over 60 cases of CMUSE or CNSU reported in the world [1],Which  
was first reportedin 1964[2], It featured by unexplained small bowel multiple superficial 
ulcers,stenosis,obstruction and  no biological signs of systematic inflammation, which are prone to 
recurrence ，Some patients are effective in hormone therapy[3].  
Comment - The above is all incorrect grammar. Comma, fullstop, sentence formation all is wrong. 
Needs revision please.  
5. In t he future, we will continue to follow up this patient, and regularly perform barium meal 
examinations of the whole digestive tract, and if necessary, perform capsule endoscopy or 
enteroscopy to observe the intestinal cavity and observe whether similar lesi ons recur.  
Comment - All statements like above are not needed. You just need to state that you shall continue 
to followup the patient and monitor for relapse of the condition. Please don't speculate. There is 
no indication for 'regular barium enema'etc. an d Capsule is contraindicated (relative 
contraindication if not absolute) in patients with suspected obstruction or adhesions.  
6. Authors have used different font types e.g. NSAID is different font type. In Short, grammar, 
language etc needs extensive revi sion for worthy scientific manuscript. Case is novel. Case is good. 
But the whole presentation, style etc needs extensive revision of content.  
7. Remove figure 2 of ct scan and also remove one histology figure. You need to include 
magnification, stains and what does the histology figure show with some arrows inside image to 
tell readers what is seen. So total 2 figures will be removed and we will  have 4 - ct scan, operative 
picture x 2 and histology.  
Thanks  
 
Publons Reviewer Recognition . Springer Nature can send verifica tion of this review directly to 
Publons (a subsidiary of Clarivate Analytics). If you would like to take advantage of this service, 
please click on the “Yes” option below. You r name, email  address, title of the reviewed 
manuscript, name of the journal, and date of your review submission (the “Review Data ”) will 
then be transmitted to Publons upon publication of the manuscript.  If you have already registered 
at Publons, they wil l notify you of the receipt of this review and update your profile as per your 
settings and their policy. If you are not registered with Publons,  you will receive an email from 
them asking you to register in order for them to be able to recognize your revi ew on your new 
profile page. Publons may use the Review Data to generate derivat ive metadata for the benefit  of 
Publons and you as a reviewer, carefully considering the sensi tivity of such information. For 
example, Publons may verify your record as a revie wer by updatin g your profile published on its 
webservice if you have registered for such service or help editors t o identify candidate reviewers. 
Please find the details of processing in Publons ’ privacy policy https://publons.com/about/terms  
 
Yes 
 
Are the m ethods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
Yes 
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
No 
 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in the manus cript or would you recommend an additional 
statistical review?  
If an additional statistical review is recommended, please speci fy what aspects require further 
assessment in your comments to the editors.  
 
Not relevant to this manuscript  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Not suitable for publication unless extensively edited  
 
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following questions:  
 
1. Have you in the past five years received reimbursements, fees, funding, or salary from an 
organisation that may in any way gain or lose financial ly from the publication of this 
manuscript, either now or in the future?  
 
2. Do you hold any stocks or shares in an organisation t hat may in any way gain or lose 
financially from the publication of t his manuscript, either now or in the future?  
 
3. Do you hold or are you currently applying for any patents  relating to the content of the 
manuscript?  
 
4. Have you received reimbursements, fees, funding, or salary from an organization that holds 
or has applie d for patents relating to the content of the manuscript?  
 
5. Do you have any other financial competing interests?  
 
6. Do you have any non -financial competing interests in relation to this paper?  
 
If you can answer no to all of the above, write 'I declare that  I have no competing interests' below.  
If your reply is yes to any, please give details below.  
 
I declare that I have no competing interests  
 
Reviewer Publication Consent. I agree for my report to be made available under an Open Access  
Creative Commons CC -BY License ( http://creativecommons.org/licenses/by/4.0 ) if this 
manuscript is accepted for publication. Any comments that I do not wish to be included in the 
published report have been included as confidential comments to the editor, wh ich will not be 
published.  If you are not happy for us to publish this report, please contact the edi torial office 
before completing the review.  If you wish, you can include your name in your publish ed report. 
Please note you must decide whether to include y our name at the start of the process and  confirm 
this decision whenever prompted. If you change your decision later, we will not be able to publish 
your name.  
 
I agree to the terms of the CC -BY 4.0 license; please do not publish my name with my report.  
(default) 
Please review this paper.
user
Reviewer ’s report  
 
Title: A case report of intestinal obstruction caused by cryptogenic multifocal ulcerous stenosing  
enteritis  
 
Version: 0 Date: 02 Jul 2020  
 
Reviewer's report:  
 
1. You should not introduce confusion of CMUSE and CNSU. If term CNSU is already given than 
you should try and use the same. An uncommon entity doesn 't deserve confusion in literature. So 
I suggest align and use term CNSU unless you believe that CNSU is a misnomer and ideal 
terminology should be CMUSE!  
2. Too many grammar and language revisions needed e.g. patient doesn't get admitted for surgical 
treatment of small bowel obstruction. Patient is admitted for symptoms of vomiting, pain etc and 
during investigations we find small bowel obstruction and hence we advocate surgical treatment 
based on some indications etc...… So your language of case presentat ion has to be refined.  
3. Conclusion - You should not write that you will continue to follow up for relapse of condition!. 
Conclusion is that clinicians should be aware of this rare or uncommon entity etc.... Raise 
awareness by reporting this entity. So ag ain, language needs to be refined please.  
4. Currently, there are only over 60 cases of CMUSE or CNSU reported in the world [1],Which  
was first reportedin 1964[2], It featured by unexplained small bowel multiple superficial 
ulcers,stenosis,obstruction and  no biological signs of systematic inflammation, which are prone to 
recurrence ，Some patients are effective in hormone therapy[3].  
Comment - The above is all incorrect grammar. Comma, fullstop, sentence formation all is wrong. 
Needs revision please.  
5. In t he future, we will continue to follow up this patient, and regularly perform barium meal 
examinations of the whole digestive tract, and if necessary, perform capsule endoscopy or 
enteroscopy to observe the intestinal cavity and observe whether similar lesi ons recur.  
Comment - All statements like above are not needed. You just need to state that you shall continue 
to followup the patient and monitor for relapse of the condition. Please don't speculate. There is 
no indication for 'regular barium enema'etc. an d Capsule is contraindicated (relative 
contraindication if not absolute) in patients with suspected obstruction or adhesions.  
6. Authors have used different font types e.g. NSAID is different font type. In Short, grammar, 
language etc needs extensive revi sion for worthy scientific manuscript. Case is novel. Case is good. 
But the whole presentation, style etc needs extensive revision of content.  
7. Remove figure 2 of ct scan and also remove one histology figure. You need to include 
magnification, stains and what does the histology figure show with some arrows inside image to 
tell readers what is seen. So total 2 figures will be removed and we will  have 4 - ct scan, operative 
picture x 2 and histology.  
Thanks  
 
Publons Reviewer Recognition . Springer Nature can send verifica tion of this review directly to 
Publons (a subsidiary of Clarivate Analytics). If you would like to take advantage of this service, 
please click on the “Yes” option below. You r name, email  address, title of the reviewed 
manuscript, name of the journal, and date of your review submission (the “Review Data ”) will 
then be transmitted to Publons upon publication of the manuscript.  If you have already registered 
at Publons, they wil l notify you of the receipt of this review and update your profile as per your 
settings and their policy. If you are not registered with Publons,  you will receive an email from 
them asking you to register in order for them to be able to recognize your revi ew on your new 
profile page. Publons may use the Review Data to generate derivat ive metadata for the benefit  of 
Publons and you as a reviewer, carefully considering the sensi tivity of such information. For 
example, Publons may verify your record as a revie wer by updatin g your profile published on its 
webservice if you have registered for such service or help editors t o identify candidate reviewers. 
Please find the details of processing in Publons ’ privacy policy https://publons.com/about/terms  
 
Yes 
 
Are the m ethods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
Yes 
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
No 
 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in the manus cript or would you recommend an additional 
statistical review?  
If an additional statistical review is recommended, please speci fy what aspects require further 
assessment in your comments to the editors.  
 
Not relevant to this manuscript  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Not suitable for publication unless extensively edited  
 
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following questions:  
 
1. Have you in the past five years received reimbursements, fees, funding, or salary from an 
organisation that may in any way gain or lose financial ly from the publication of this 
manuscript, either now or in the future?  
 
2. Do you hold any stocks or shares in an organisation t hat may in any way gain or lose 
financially from the publication of t his manuscript, either now or in the future?  
 
3. Do you hold or are you currently applying for any patents  relating to the content of the 
manuscript?  
 
4. Have you received reimbursements, fees, funding, or salary from an organization that holds 
or has applie d for patents relating to the content of the manuscript?  
 
5. Do you have any other financial competing interests?  
 
6. Do you have any non -financial competing interests in relation to this paper?  
 
If you can answer no to all of the above, write 'I declare that  I have no competing interests' below.  
If your reply is yes to any, please give details below.  
 
I declare that I have no competing interests  
 
Reviewer Publication Consent. I agree for my report to be made available under an Open Access  
Creative Commons CC -BY License ( http://creativecommons.org/licenses/by/4.0 ) if this 
manuscript is accepted for publication. Any comments that I do not wish to be included in the 
published report have been included as confidential comments to the editor, wh ich will not be 
published.  If you are not happy for us to publish this report, please contact the edi torial office 
before completing the review.  If you wish, you can include your name in your publish ed report. 
Please note you must decide whether to include y our name at the start of the process and  confirm 
this decision whenever prompted. If you change your decision later, we will not be able to publish 
your name.  
 
I agree to the terms of the CC -BY 4.0 license; please do not publish my name with my report.  
(default) 
assistant