Title: The Association Between Oxidative Balance Score with Constipation and Diarrhea in US
Adults: A Cross-sectional Analysis of NHANES 2007–2010
Version: 2 Date: 23 Nov 2024
Reviewer's report:
Congratulations on the development of your research regarding the relationship between diet,
specifically oxidative stress, and intestinal symptoms. Your findings contribute valuable insights
to this important area of study.
I would like to offer a few comments for your consideration. Firstly, it may be beneficial to
include in the limitations section that the medications received by the sample population were
not evaluated. This is particularly relevant for conditions such as depression and diabetes, which
could potentially influence the development of diarrhea and constipation.
Additionally, I suggest clarifying the clinical implications of your findings in the discussion
section. The final statement in the conclusions may lead to some ambiguity. It is challenging to
recommend a specific diet for men to prevent constipation and for women to prevent diarrhea
when we cannot predict which symptom they will develop. This recommendation might only be
applicable in higher-risk situations, such as when associated with certain medications or aimed
at preventing symptom relapses in the context of functional disorders.
In the event that it is not possible to make a specific recommendation, I believe it should be
addressed that there is a limitation in the findings for establishing concrete recommendations
in clinical practice, using a less assertive phrase than the one used in the conclusions: 'The
results indicate that maintaining an antioxidant-rich diet is essential for preventing the risk of
constipation in males and diarrhea in females´.
Thank you for considering these suggestions, and I look forward to seeing how your work
evolves.
Best regards.
Title: The Association Between Oxidative Balance Score with Constipation and Diarrhea in US
Adults: A Cross-sectional Analysis of NHANES 2007–2010
Version: 2 Date: 23 Nov 2024
Reviewer's report:
Congratulations on the development of your research regarding the relationship between diet,
specifically oxidative stress, and intestinal symptoms. Your findings contribute valuable insights
to this important area of study.
I would like to offer a few comments for your consideration. Firstly, it may be beneficial to
include in the limitations section that the medications received by the sample population were
not evaluated. This is particularly relevant for conditions such as depression and diabetes, which
could potentially influence the development of diarrhea and constipation.
Additionally, I suggest clarifying the clinical implications of your findings in the discussion
section. The final statement in the conclusions may lead to some ambiguity. It is challenging to
recommend a specific diet for men to prevent constipation and for women to prevent diarrhea
when we cannot predict which symptom they will develop. This recommendation might only be
applicable in higher-risk situations, such as when associated with certain medications or aimed
at preventing symptom relapses in the context of functional disorders.
In the event that it is not possible to make a specific recommendation, I believe it should be
addressed that there is a limitation in the findings for establishing concrete recommendations
in clinical practice, using a less assertive phrase than the one used in the conclusions: 'The
results indicate that maintaining an antioxidant-rich diet is essential for preventing the risk of
constipation in males and diarrhea in females´.
Thank you for considering these suggestions, and I look forward to seeing how your work
evolves.
Best regards.
Please review this paper.
user
Title: The Association Between Oxidative Balance Score with Constipation and Diarrhea in US
Adults: A Cross-sectional Analysis of NHANES 2007–2010
Version: 2 Date: 23 Nov 2024
Reviewer's report:
Congratulations on the development of your research regarding the relationship between diet,
specifically oxidative stress, and intestinal symptoms. Your findings contribute valuable insights
to this important area of study.
I would like to offer a few comments for your consideration. Firstly, it may be beneficial to
include in the limitations section that the medications received by the sample population were
not evaluated. This is particularly relevant for conditions such as depression and diabetes, which
could potentially influence the development of diarrhea and constipation.
Additionally, I suggest clarifying the clinical implications of your findings in the discussion
section. The final statement in the conclusions may lead to some ambiguity. It is challenging to
recommend a specific diet for men to prevent constipation and for women to prevent diarrhea
when we cannot predict which symptom they will develop. This recommendation might only be
applicable in higher-risk situations, such as when associated with certain medications or aimed
at preventing symptom relapses in the context of functional disorders.
In the event that it is not possible to make a specific recommendation, I believe it should be
addressed that there is a limitation in the findings for establishing concrete recommendations
in clinical practice, using a less assertive phrase than the one used in the conclusions: 'The
results indicate that maintaining an antioxidant-rich diet is essential for preventing the risk of
constipation in males and diarrhea in females´.
Thank you for considering these suggestions, and I look forward to seeing how your work
evolves.
Best regards.
assistant