Reviewer's report
Title:Using an oblique incident laser beam to measure the optical properties of
stomach mucosa/submucosa tissue
Version: 1Date:12 June 2008
Reviewer: Alexey N Bashkatov
Reviewer's report:
In this paper the authors investigated the optical properties of stomach tissues.
The study is very interesting and important for tissue optics, and data presented
in the paper can be used for many medical applications. Therefore, the paper of
Wei et al. is very important and relevant and so the paper may be accepted to
publishing in BMC Gastroenterology. However, some remarks should be
corrected before the acceptance. They are listed below.
1. In this paper measure the absorption and reduced scattering coefficients of
stomach tissues using the reflectance spectroscopy in the wavelength range
from 635 to 980 nm. Results of these measurements are presented in figs. 2 and
3. However, the authors not compare the results with similar results obtained by
other authors (for example, Bashkatov A.N., et al. Optical properties of human
stomach mucosa in the spectral range from 400 to 2000 nm: prognosis for
gastroenterology // Medical Laser Application, Vol. 22, P. 95-104, 2007; Holmer
C., et al. Optical properties of adenocarcinoma and squamous cell carcinoma of
the gastroesophageal junction // J. Biomed. Opt., Vol. 12, N. 1, 014025, 2007;
etc). Thus, comparison between results presented in the reviewed paper and
obtained other authors should be performed.
2. In last paragraph of Section "Discussion" the authors write: "Fig. 6 shows that
the diffuse reflectance for tissue samples are 0.456 mm-1 at 635 nm and drops
to 0.425 mm-1 at 730 nm…". However, it is well known, that reflectance is
dimensionless parameter, and, so, not clear how the reflectance coefficient was
measured in units of inverse millimeters.
3. In Section "Materials and Methods" (Subsection "Theory") after Eq. 7 authors
write: "with m's the reduced scattering coefficient, i.e. m's (1-g)…" The "m's (1-g)"
should be changed to ms (1-g)
4. Ref. 19: "J. Swartling, J.S. Dam, and S. Andersson-Engels, "Comparison of
spatially and temporally resolved diffuse-reflectance measurement systems for
determination of biomedical properties," Appl. Opt., vol. 42, pp. 4612-4620,
2003." should be changed by "J. Swartling, J.S. Dam, and S. Andersson-Engels,
"Comparison of spatially and temporally resolved diffuse-reflectance
measurement systems for determination of biomedical optical properties," Appl.
Opt., vol. 42, pp. 4612-4620, 2003."
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests
Reviewer's report
Title:Using an oblique incident laser beam to measure the optical properties of
stomach mucosa/submucosa tissue
Version: 1Date:12 June 2008
Reviewer: Alexey N Bashkatov
Reviewer's report:
In this paper the authors investigated the optical properties of stomach tissues.
The study is very interesting and important for tissue optics, and data presented
in the paper can be used for many medical applications. Therefore, the paper of
Wei et al. is very important and relevant and so the paper may be accepted to
publishing in BMC Gastroenterology. However, some remarks should be
corrected before the acceptance. They are listed below.
1. In this paper measure the absorption and reduced scattering coefficients of
stomach tissues using the reflectance spectroscopy in the wavelength range
from 635 to 980 nm. Results of these measurements are presented in figs. 2 and
3. However, the authors not compare the results with similar results obtained by
other authors (for example, Bashkatov A.N., et al. Optical properties of human
stomach mucosa in the spectral range from 400 to 2000 nm: prognosis for
gastroenterology // Medical Laser Application, Vol. 22, P. 95-104, 2007; Holmer
C., et al. Optical properties of adenocarcinoma and squamous cell carcinoma of
the gastroesophageal junction // J. Biomed. Opt., Vol. 12, N. 1, 014025, 2007;
etc). Thus, comparison between results presented in the reviewed paper and
obtained other authors should be performed.
2. In last paragraph of Section "Discussion" the authors write: "Fig. 6 shows that
the diffuse reflectance for tissue samples are 0.456 mm-1 at 635 nm and drops
to 0.425 mm-1 at 730 nm…". However, it is well known, that reflectance is
dimensionless parameter, and, so, not clear how the reflectance coefficient was
measured in units of inverse millimeters.
3. In Section "Materials and Methods" (Subsection "Theory") after Eq. 7 authors
write: "with m's the reduced scattering coefficient, i.e. m's (1-g)…" The "m's (1-g)"
should be changed to ms (1-g)
4. Ref. 19: "J. Swartling, J.S. Dam, and S. Andersson-Engels, "Comparison of
spatially and temporally resolved diffuse-reflectance measurement systems for
determination of biomedical properties," Appl. Opt., vol. 42, pp. 4612-4620,
2003." should be changed by "J. Swartling, J.S. Dam, and S. Andersson-Engels,
"Comparison of spatially and temporally resolved diffuse-reflectance
measurement systems for determination of biomedical optical properties," Appl.
Opt., vol. 42, pp. 4612-4620, 2003."
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests
Please review this paper.
user
Reviewer's report
Title:Using an oblique incident laser beam to measure the optical properties of
stomach mucosa/submucosa tissue
Version: 1Date:12 June 2008
Reviewer: Alexey N Bashkatov
Reviewer's report:
In this paper the authors investigated the optical properties of stomach tissues.
The study is very interesting and important for tissue optics, and data presented
in the paper can be used for many medical applications. Therefore, the paper of
Wei et al. is very important and relevant and so the paper may be accepted to
publishing in BMC Gastroenterology. However, some remarks should be
corrected before the acceptance. They are listed below.
1. In this paper measure the absorption and reduced scattering coefficients of
stomach tissues using the reflectance spectroscopy in the wavelength range
from 635 to 980 nm. Results of these measurements are presented in figs. 2 and
3. However, the authors not compare the results with similar results obtained by
other authors (for example, Bashkatov A.N., et al. Optical properties of human
stomach mucosa in the spectral range from 400 to 2000 nm: prognosis for
gastroenterology // Medical Laser Application, Vol. 22, P. 95-104, 2007; Holmer
C., et al. Optical properties of adenocarcinoma and squamous cell carcinoma of
the gastroesophageal junction // J. Biomed. Opt., Vol. 12, N. 1, 014025, 2007;
etc). Thus, comparison between results presented in the reviewed paper and
obtained other authors should be performed.
2. In last paragraph of Section "Discussion" the authors write: "Fig. 6 shows that
the diffuse reflectance for tissue samples are 0.456 mm-1 at 635 nm and drops
to 0.425 mm-1 at 730 nm…". However, it is well known, that reflectance is
dimensionless parameter, and, so, not clear how the reflectance coefficient was
measured in units of inverse millimeters.
3. In Section "Materials and Methods" (Subsection "Theory") after Eq. 7 authors
write: "with m's the reduced scattering coefficient, i.e. m's (1-g)…" The "m's (1-g)"
should be changed to ms (1-g)
4. Ref. 19: "J. Swartling, J.S. Dam, and S. Andersson-Engels, "Comparison of
spatially and temporally resolved diffuse-reflectance measurement systems for
determination of biomedical properties," Appl. Opt., vol. 42, pp. 4612-4620,
2003." should be changed by "J. Swartling, J.S. Dam, and S. Andersson-Engels,
"Comparison of spatially and temporally resolved diffuse-reflectance
measurement systems for determination of biomedical optical properties," Appl.
Opt., vol. 42, pp. 4612-4620, 2003."
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests
assistant