Reviewer's report
Title:Gene expression analysis of a Helicobacter pylori-infected and high-salt
diet-treated mouse gastric tumor model: Identification of CD177 as a novel
prognostic factor in patients with gastric cancer
Version: 2Date:21 March 2013
Reviewer: Thomas Wex
Reviewer's report:
Overall, the authors have addressed the points of criticisms raised in the
previous report appropriately.
- Please correct Table 2. Depth of invasion is presented from 53 instead of 55
patients (essential)
- Numbers of animals that died or became moribund should be presented
detailed for the groups B, C, and D (see page 8). (essential)
- Group D is the most interesting group with respect to the topic of this
manuscript. However, more than 1/3 (6 out of 15) of all animals were excluded
from this group. Is there any further information available from these animals,
and does the exclusion of these animals affect the overall conclusion? The
authors could shortly discuss this aspect. (discretionary)
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
'I declare that I have no competing interests'
Reviewer's report
Title:Gene expression analysis of a Helicobacter pylori-infected and high-salt
diet-treated mouse gastric tumor model: Identification of CD177 as a novel
prognostic factor in patients with gastric cancer
Version: 2Date:21 March 2013
Reviewer: Thomas Wex
Reviewer's report:
Overall, the authors have addressed the points of criticisms raised in the
previous report appropriately.
- Please correct Table 2. Depth of invasion is presented from 53 instead of 55
patients (essential)
- Numbers of animals that died or became moribund should be presented
detailed for the groups B, C, and D (see page 8). (essential)
- Group D is the most interesting group with respect to the topic of this
manuscript. However, more than 1/3 (6 out of 15) of all animals were excluded
from this group. Is there any further information available from these animals,
and does the exclusion of these animals affect the overall conclusion? The
authors could shortly discuss this aspect. (discretionary)
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
'I declare that I have no competing interests'
Please review this paper.
user
Reviewer's report
Title:Gene expression analysis of a Helicobacter pylori-infected and high-salt
diet-treated mouse gastric tumor model: Identification of CD177 as a novel
prognostic factor in patients with gastric cancer
Version: 2Date:21 March 2013
Reviewer: Thomas Wex
Reviewer's report:
Overall, the authors have addressed the points of criticisms raised in the
previous report appropriately.
- Please correct Table 2. Depth of invasion is presented from 53 instead of 55
patients (essential)
- Numbers of animals that died or became moribund should be presented
detailed for the groups B, C, and D (see page 8). (essential)
- Group D is the most interesting group with respect to the topic of this
manuscript. However, more than 1/3 (6 out of 15) of all animals were excluded
from this group. Is there any further information available from these animals,
and does the exclusion of these animals affect the overall conclusion? The
authors could shortly discuss this aspect. (discretionary)
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
'I declare that I have no competing interests'
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