Title: Operation Sequence of Bidirectional Endoscopy with Topical Anesthesia Affected
Colonoscopy Performance: A Randomized Controlled Trial
Version: 1 Date: 17 Feb 2025
Reviewer:  Yu-Tse Chiu
Reviewer's report:
The authors have adequately addressed the issues raised in the previous review, resulting in
a well-written manuscript. Regarding the validation of the AI system, while it is unfortunate
that no large-scale trials currently support its reliability, certification by relevant authorities
still provides a certain level of quality assurance. However, although the authors clarified the
rationale for the discrepancy between the target sample size and the actual recruitment number
in their point-by-point response, this explanation was not included in the manuscript. This
omission could potentially confuse readers, particularly since the sample size calculation section
immediately precedes the results section. The manuscript would be further improved if the
authors included this clarification. Otherwise, I believe no further modifications are necessary.
Title: Operation Sequence of Bidirectional Endoscopy with Topical Anesthesia Affected
Colonoscopy Performance: A Randomized Controlled Trial
Version: 1 Date: 17 Feb 2025
Reviewer:  Yu-Tse Chiu
Reviewer's report:
The authors have adequately addressed the issues raised in the previous review, resulting in
a well-written manuscript. Regarding the validation of the AI system, while it is unfortunate
that no large-scale trials currently support its reliability, certification by relevant authorities
still provides a certain level of quality assurance. However, although the authors clarified the
rationale for the discrepancy between the target sample size and the actual recruitment number
in their point-by-point response, this explanation was not included in the manuscript. This
omission could potentially confuse readers, particularly since the sample size calculation section
immediately precedes the results section. The manuscript would be further improved if the
authors included this clarification. Otherwise, I believe no further modifications are necessary.
Please review this paper.
user
Title: Operation Sequence of Bidirectional Endoscopy with Topical Anesthesia Affected
Colonoscopy Performance: A Randomized Controlled Trial
Version: 1 Date: 17 Feb 2025
Reviewer:  Yu-Tse Chiu
Reviewer's report:
The authors have adequately addressed the issues raised in the previous review, resulting in
a well-written manuscript. Regarding the validation of the AI system, while it is unfortunate
that no large-scale trials currently support its reliability, certification by relevant authorities
still provides a certain level of quality assurance. However, although the authors clarified the
rationale for the discrepancy between the target sample size and the actual recruitment number
in their point-by-point response, this explanation was not included in the manuscript. This
omission could potentially confuse readers, particularly since the sample size calculation section
immediately precedes the results section. The manuscript would be further improved if the
authors included this clarification. Otherwise, I believe no further modifications are necessary.
assistant