Title: Combining Endoscopic variceal ligation and omeprazole sodium in treating upper
gastrointestinal hemorrhage combined with liver cirrhosis
Version: 1 Date: 23 Feb 2025
Reviewer's report:
Dear authors,
I read your manuscript, " Combining Endoscopic Variceal Liquidation and omeprazole sodium
in Treating Upper Gastrointestinal Hemorrhage Combined with Liver Cirrhosis," with great
interest.
I consider it important to establish the role of Proton pump inhibitors (IPP) in the treatment of
esophageal ulcers after ligation of esophageal varices.
Still, I have some remarks:
1. I think it would be best to emphasize the actual guidelines statements regarding variceal
bleeding in cirrhosis. This may be done in the introduction or discussion section.
2. In the material and method section it should be mentioned the medical background of these
patients should be related to beta-blockers and to mention the additional treatments, such as
vasopressin analogs or octreotide, which are also used in treating acute variceal bleeding. I
mention the missing data regarding previous or concomitant medication ( beta-blockers or
vasopressin analogs). Moreover, the authors should discuss the existing recommendations
regarding variceal bleeding in a cirrhotic patient. It should also be mentioned if the patient
received antibiotics.
3. I recommend mentioning how the parameters for the splenic and portal veins were determined
in the results section.
The statistics should take these into consideration.
Title: Combining Endoscopic variceal ligation and omeprazole sodium in treating upper
gastrointestinal hemorrhage combined with liver cirrhosis
Version: 1 Date: 23 Feb 2025
Reviewer's report:
Dear authors,
I read your manuscript, " Combining Endoscopic Variceal Liquidation and omeprazole sodium
in Treating Upper Gastrointestinal Hemorrhage Combined with Liver Cirrhosis," with great
interest.
I consider it important to establish the role of Proton pump inhibitors (IPP) in the treatment of
esophageal ulcers after ligation of esophageal varices.
Still, I have some remarks:
1. I think it would be best to emphasize the actual guidelines statements regarding variceal
bleeding in cirrhosis. This may be done in the introduction or discussion section.
2. In the material and method section it should be mentioned the medical background of these
patients should be related to beta-blockers and to mention the additional treatments, such as
vasopressin analogs or octreotide, which are also used in treating acute variceal bleeding. I
mention the missing data regarding previous or concomitant medication ( beta-blockers or
vasopressin analogs). Moreover, the authors should discuss the existing recommendations
regarding variceal bleeding in a cirrhotic patient. It should also be mentioned if the patient
received antibiotics.
3. I recommend mentioning how the parameters for the splenic and portal veins were determined
in the results section.
The statistics should take these into consideration.
Please review this paper.
user
Title: Combining Endoscopic variceal ligation and omeprazole sodium in treating upper
gastrointestinal hemorrhage combined with liver cirrhosis
Version: 1 Date: 23 Feb 2025
Reviewer's report:
Dear authors,
I read your manuscript, " Combining Endoscopic Variceal Liquidation and omeprazole sodium
in Treating Upper Gastrointestinal Hemorrhage Combined with Liver Cirrhosis," with great
interest.
I consider it important to establish the role of Proton pump inhibitors (IPP) in the treatment of
esophageal ulcers after ligation of esophageal varices.
Still, I have some remarks:
1. I think it would be best to emphasize the actual guidelines statements regarding variceal
bleeding in cirrhosis. This may be done in the introduction or discussion section.
2. In the material and method section it should be mentioned the medical background of these
patients should be related to beta-blockers and to mention the additional treatments, such as
vasopressin analogs or octreotide, which are also used in treating acute variceal bleeding. I
mention the missing data regarding previous or concomitant medication ( beta-blockers or
vasopressin analogs). Moreover, the authors should discuss the existing recommendations
regarding variceal bleeding in a cirrhotic patient. It should also be mentioned if the patient
received antibiotics.
3. I recommend mentioning how the parameters for the splenic and portal veins were determined
in the results section.
The statistics should take these into consideration.
assistant