Title: Network meta-analysis of adjuvant treatments for patients with hepatocellular carcinoma
after curative resection
Version: 1 Date: 04 Jul 2023
Reviewer's report:
The prevention of recurrence for patients with hepatocellular carcinoma after curative resection
is still a great challenge in clinical practice. In this article, the authors compared the efficacy
between different reported treatments by network meta-analysis. Generally, this is an interesting
and well-organized study. I have only a few suggestions.
In the conclusion of abstract, you mentioned that ‘Large scale of RCTs are needed to verify it.’
It is redundant, please remove.
Has this meta-analysis been registered?
You may consider additionally perform Q test to assess heterogeneity.
I noticed that the authors missed a few important studies regarding the background of
HCC. For example, Biosci Trends. 2022 Dec 26;16(6):405-425. doi: 10.5582/bst.2022.01109;
J Cell Physiol. 2019 Feb;234(2):1062-1070. doi: 10.1002/jcp.27324; J Cell Physiol. 2019
Aug;234(8):12116-12121. doi: 10.1002/jcp.28019. Epub 2019 Jan 15.
Title: Network meta-analysis of adjuvant treatments for patients with hepatocellular carcinoma
after curative resection
Version: 1 Date: 04 Jul 2023
Reviewer's report:
The prevention of recurrence for patients with hepatocellular carcinoma after curative resection
is still a great challenge in clinical practice. In this article, the authors compared the efficacy
between different reported treatments by network meta-analysis. Generally, this is an interesting
and well-organized study. I have only a few suggestions.
In the conclusion of abstract, you mentioned that ‘Large scale of RCTs are needed to verify it.’
It is redundant, please remove.
Has this meta-analysis been registered?
You may consider additionally perform Q test to assess heterogeneity.
I noticed that the authors missed a few important studies regarding the background of
HCC. For example, Biosci Trends. 2022 Dec 26;16(6):405-425. doi: 10.5582/bst.2022.01109;
J Cell Physiol. 2019 Feb;234(2):1062-1070. doi: 10.1002/jcp.27324; J Cell Physiol. 2019
Aug;234(8):12116-12121. doi: 10.1002/jcp.28019. Epub 2019 Jan 15.
Please review this paper.
user
Title: Network meta-analysis of adjuvant treatments for patients with hepatocellular carcinoma
after curative resection
Version: 1 Date: 04 Jul 2023
Reviewer's report:
The prevention of recurrence for patients with hepatocellular carcinoma after curative resection
is still a great challenge in clinical practice. In this article, the authors compared the efficacy
between different reported treatments by network meta-analysis. Generally, this is an interesting
and well-organized study. I have only a few suggestions.
In the conclusion of abstract, you mentioned that ‘Large scale of RCTs are needed to verify it.’
It is redundant, please remove.
Has this meta-analysis been registered?
You may consider additionally perform Q test to assess heterogeneity.
I noticed that the authors missed a few important studies regarding the background of
HCC. For example, Biosci Trends. 2022 Dec 26;16(6):405-425. doi: 10.5582/bst.2022.01109;
J Cell Physiol. 2019 Feb;234(2):1062-1070. doi: 10.1002/jcp.27324; J Cell Physiol. 2019
Aug;234(8):12116-12121. doi: 10.1002/jcp.28019. Epub 2019 Jan 15.
assistant