Title: The impact of endoscopist performance and patient factors on distal adenoma detection
and colorectal cancer incidence.
Version: 1 Date: 04 Dec 2023
Reviewer's report:
In this study, authors assessed the impact of endoscopists’ performance and patient factors
on distal adenoma detection and colorectal cancer incidence. A large number of patients were
registered in this trial and more than 34,000 participants received flexible sigmoidoscopy
screening in the 13 centres. Median follow-up was 17 years. After a detailed statistical analysis,
they found that bowel preparation quality and longer insertion and withdrawal time were key
for improving distal adenoma detection. Additionally, it was indicated that higher ADRs were
associated with a lower risk of distal CRC. The main research findings of this paper will be
important for prediction and prevention of distal CRC. I have no practical criticisms in terms
of methods, results and interpretation.
Title: The impact of endoscopist performance and patient factors on distal adenoma detection
and colorectal cancer incidence.
Version: 1 Date: 04 Dec 2023
Reviewer's report:
In this study, authors assessed the impact of endoscopists’ performance and patient factors
on distal adenoma detection and colorectal cancer incidence. A large number of patients were
registered in this trial and more than 34,000 participants received flexible sigmoidoscopy
screening in the 13 centres. Median follow-up was 17 years. After a detailed statistical analysis,
they found that bowel preparation quality and longer insertion and withdrawal time were key
for improving distal adenoma detection. Additionally, it was indicated that higher ADRs were
associated with a lower risk of distal CRC. The main research findings of this paper will be
important for prediction and prevention of distal CRC. I have no practical criticisms in terms
of methods, results and interpretation.
Please review this paper.
user
Title: The impact of endoscopist performance and patient factors on distal adenoma detection
and colorectal cancer incidence.
Version: 1 Date: 04 Dec 2023
Reviewer's report:
In this study, authors assessed the impact of endoscopists’ performance and patient factors
on distal adenoma detection and colorectal cancer incidence. A large number of patients were
registered in this trial and more than 34,000 participants received flexible sigmoidoscopy
screening in the 13 centres. Median follow-up was 17 years. After a detailed statistical analysis,
they found that bowel preparation quality and longer insertion and withdrawal time were key
for improving distal adenoma detection. Additionally, it was indicated that higher ADRs were
associated with a lower risk of distal CRC. The main research findings of this paper will be
important for prediction and prevention of distal CRC. I have no practical criticisms in terms
of methods, results and interpretation.
assistant