Reviewer's report
Title:Correlation between the methylation of SULF2 and WRN promoter and the
irinotecan chemosensitivity in gastric cancer
Version: 4Date:20 September 2013
Reviewer: Gyeong Hoon Kang
Reviewer's report:
Minor Essential Revisions.
1. Why did the authors use 1997 AJCC staging rather than 2003 AJCC staging
for the gastrectomy samples which were from 2009 to 2011?
2. The authors should delete "MethyLight" in the sentence "The
fluorescence-based real-time PCR assay, MethyLight, was used in the detection
of methylated DNA." becuase the authors did not perform the MethyLight
technology.
Level of interest: An article of importance in its field
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests.
Reviewer's report
Title:Correlation between the methylation of SULF2 and WRN promoter and the
irinotecan chemosensitivity in gastric cancer
Version: 4Date:20 September 2013
Reviewer: Gyeong Hoon Kang
Reviewer's report:
Minor Essential Revisions.
1. Why did the authors use 1997 AJCC staging rather than 2003 AJCC staging
for the gastrectomy samples which were from 2009 to 2011?
2. The authors should delete "MethyLight" in the sentence "The
fluorescence-based real-time PCR assay, MethyLight, was used in the detection
of methylated DNA." becuase the authors did not perform the MethyLight
technology.
Level of interest: An article of importance in its field
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests.
Please review this paper.
user
Reviewer's report
Title:Correlation between the methylation of SULF2 and WRN promoter and the
irinotecan chemosensitivity in gastric cancer
Version: 4Date:20 September 2013
Reviewer: Gyeong Hoon Kang
Reviewer's report:
Minor Essential Revisions.
1. Why did the authors use 1997 AJCC staging rather than 2003 AJCC staging
for the gastrectomy samples which were from 2009 to 2011?
2. The authors should delete "MethyLight" in the sentence "The
fluorescence-based real-time PCR assay, MethyLight, was used in the detection
of methylated DNA." becuase the authors did not perform the MethyLight
technology.
Level of interest: An article of importance in its field
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests.
assistant