Reviewer's report
Title:Outcomes in Culture Positive and Culture Negative Ascitic Fluid Infection in
Patients with Viral Cirrhosis: Cohort Study
Version: 2Date:14 September 2008
Reviewer: Sang Hoon Ahn
Reviewer's report:
This retrospective study examined the outcome and predictors for the survival in
cirrhotic patients with ascitic fluid infection. The authors found that the patients
with culture positive (SBP) had a higher in-hospital mortality compared to those
culture negative (CNNA), and independent predictors for the survival included
lower serum creatinine level and blood culture negativity.
This study addressed an interesting issue that has not been confirmed
previously. The supplement for the following points would improve the
manuscript.
Comments
1. The author should show the survival curve depicting the difference of
in-hospital mortality between SBP and CNNA group. In addition, please add the
table that shows the list of predictors for the survival and statistical results on
uni/multi-variate analysis described on page 10.
2. Describe the cause of death. How many patients died of ascitic fluid infection
rather than of other cirrhotic complications?
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: Yes, and I have assessed the statistics in my report.
Declaration of competing interests:
I declare that I have no competing interests.
Reviewer's report
Title:Outcomes in Culture Positive and Culture Negative Ascitic Fluid Infection in
Patients with Viral Cirrhosis: Cohort Study
Version: 2Date:14 September 2008
Reviewer: Sang Hoon Ahn
Reviewer's report:
This retrospective study examined the outcome and predictors for the survival in
cirrhotic patients with ascitic fluid infection. The authors found that the patients
with culture positive (SBP) had a higher in-hospital mortality compared to those
culture negative (CNNA), and independent predictors for the survival included
lower serum creatinine level and blood culture negativity.
This study addressed an interesting issue that has not been confirmed
previously. The supplement for the following points would improve the
manuscript.
Comments
1. The author should show the survival curve depicting the difference of
in-hospital mortality between SBP and CNNA group. In addition, please add the
table that shows the list of predictors for the survival and statistical results on
uni/multi-variate analysis described on page 10.
2. Describe the cause of death. How many patients died of ascitic fluid infection
rather than of other cirrhotic complications?
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: Yes, and I have assessed the statistics in my report.
Declaration of competing interests:
I declare that I have no competing interests.
Please review this paper.
user
Reviewer's report
Title:Outcomes in Culture Positive and Culture Negative Ascitic Fluid Infection in
Patients with Viral Cirrhosis: Cohort Study
Version: 2Date:14 September 2008
Reviewer: Sang Hoon Ahn
Reviewer's report:
This retrospective study examined the outcome and predictors for the survival in
cirrhotic patients with ascitic fluid infection. The authors found that the patients
with culture positive (SBP) had a higher in-hospital mortality compared to those
culture negative (CNNA), and independent predictors for the survival included
lower serum creatinine level and blood culture negativity.
This study addressed an interesting issue that has not been confirmed
previously. The supplement for the following points would improve the
manuscript.
Comments
1. The author should show the survival curve depicting the difference of
in-hospital mortality between SBP and CNNA group. In addition, please add the
table that shows the list of predictors for the survival and statistical results on
uni/multi-variate analysis described on page 10.
2. Describe the cause of death. How many patients died of ascitic fluid infection
rather than of other cirrhotic complications?
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: Yes, and I have assessed the statistics in my report.
Declaration of competing interests:
I declare that I have no competing interests.
assistant