Reviewer's report
Title:A case series in patients with enteropathy and chronic granulomatous
diseases
Version:2Date:12 March 2015
Reviewer: Rashid Lui
Reviewer's report:
Minor Essential Revisions
page 7
line 4 to 7. May I ask whether imaging i.e. MRI spine or lumbar puncture was
done for the spastic paraparesis, and if so to include it in the case report.
Line 6 could you also provide details on the nerve conduction tests for the
inflammatory neuropathy diagnosis.
Line 6. please clarify whether the immunoglobulins were treating the neuropathy
or the spastic paraparesis.
Discretionary Revisions
In the supplementary tables you have provided, consider adding other
information i.e. the HLA-DRE/DQ2 haploype status
Can also consider mentioning the state of diet (gluten free vs normal), and also
response to treatment
Can state the impact of this association to clinical practice i.e. predict or monitor
response gluten free diet.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
I declare that I have no competing interests
Reviewer's report
Title:A case series in patients with enteropathy and chronic granulomatous
diseases
Version:2Date:12 March 2015
Reviewer: Rashid Lui
Reviewer's report:
Minor Essential Revisions
page 7
line 4 to 7. May I ask whether imaging i.e. MRI spine or lumbar puncture was
done for the spastic paraparesis, and if so to include it in the case report.
Line 6 could you also provide details on the nerve conduction tests for the
inflammatory neuropathy diagnosis.
Line 6. please clarify whether the immunoglobulins were treating the neuropathy
or the spastic paraparesis.
Discretionary Revisions
In the supplementary tables you have provided, consider adding other
information i.e. the HLA-DRE/DQ2 haploype status
Can also consider mentioning the state of diet (gluten free vs normal), and also
response to treatment
Can state the impact of this association to clinical practice i.e. predict or monitor
response gluten free diet.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
I declare that I have no competing interests
Please review this paper.
user
Reviewer's report
Title:A case series in patients with enteropathy and chronic granulomatous
diseases
Version:2Date:12 March 2015
Reviewer: Rashid Lui
Reviewer's report:
Minor Essential Revisions
page 7
line 4 to 7. May I ask whether imaging i.e. MRI spine or lumbar puncture was
done for the spastic paraparesis, and if so to include it in the case report.
Line 6 could you also provide details on the nerve conduction tests for the
inflammatory neuropathy diagnosis.
Line 6. please clarify whether the immunoglobulins were treating the neuropathy
or the spastic paraparesis.
Discretionary Revisions
In the supplementary tables you have provided, consider adding other
information i.e. the HLA-DRE/DQ2 haploype status
Can also consider mentioning the state of diet (gluten free vs normal), and also
response to treatment
Can state the impact of this association to clinical practice i.e. predict or monitor
response gluten free diet.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
I declare that I have no competing interests
assistant