Title: Title: Immediate postoperative parenteral anticoagulant therapy in patients with
mesenteric ischemia after intestinal resection – A retrospective cohort study at a single institute.
Version: 3 Date: 25 Mar 2022
Reviewer's report:
This study aimed to elucidate the benefits of postoperative parenteral anticoagulant in patients
with AMI and intestinal resection.
There were some limitations:
1. Page 2 conclusion part: There is an unnecessary “s” behind “improves”.
2. Page 6 Line 3: There is an unnecessary “o” behind “patients”.
3. Would the author introduce the preoperative anticoagulation strategy? The author mentioned
in the paper that nineteen patients had recent major cardiovascular procedures.
4.  Some enrolled patients may have a long hospital stay, even some may be more than 30 days.
So would the in-hospital mortality other than the overall 30-day mortality reflect the real-world
perioperative data?
5.  Would the author can introduce more perioperative details for us, including the arrythmia,
anastomosis leakage, and length of stay? How many patients underwent one-stage anastomosis
and how many patient do not underwent anastomosis? How may patients underwent
postoperative bleeding which needed extra operation? Are there any patients suffer from
postoperative bleeding of important organs?
6. Would the author tell us the indication to administrate the enoxaparin?
7. There were so many confounding factors. It is hard to draw the conclusion that the
postoperative parenteral anticoagulants would benefit the patients, just by multivariate analysis.
Title: Title: Immediate postoperative parenteral anticoagulant therapy in patients with
mesenteric ischemia after intestinal resection – A retrospective cohort study at a single institute.
Version: 3 Date: 25 Mar 2022
Reviewer's report:
This study aimed to elucidate the benefits of postoperative parenteral anticoagulant in patients
with AMI and intestinal resection.
There were some limitations:
1. Page 2 conclusion part: There is an unnecessary “s” behind “improves”.
2. Page 6 Line 3: There is an unnecessary “o” behind “patients”.
3. Would the author introduce the preoperative anticoagulation strategy? The author mentioned
in the paper that nineteen patients had recent major cardiovascular procedures.
4.  Some enrolled patients may have a long hospital stay, even some may be more than 30 days.
So would the in-hospital mortality other than the overall 30-day mortality reflect the real-world
perioperative data?
5.  Would the author can introduce more perioperative details for us, including the arrythmia,
anastomosis leakage, and length of stay? How many patients underwent one-stage anastomosis
and how many patient do not underwent anastomosis? How may patients underwent
postoperative bleeding which needed extra operation? Are there any patients suffer from
postoperative bleeding of important organs?
6. Would the author tell us the indication to administrate the enoxaparin?
7. There were so many confounding factors. It is hard to draw the conclusion that the
postoperative parenteral anticoagulants would benefit the patients, just by multivariate analysis.
Please review this paper.
user
Title: Title: Immediate postoperative parenteral anticoagulant therapy in patients with
mesenteric ischemia after intestinal resection – A retrospective cohort study at a single institute.
Version: 3 Date: 25 Mar 2022
Reviewer's report:
This study aimed to elucidate the benefits of postoperative parenteral anticoagulant in patients
with AMI and intestinal resection.
There were some limitations:
1. Page 2 conclusion part: There is an unnecessary “s” behind “improves”.
2. Page 6 Line 3: There is an unnecessary “o” behind “patients”.
3. Would the author introduce the preoperative anticoagulation strategy? The author mentioned
in the paper that nineteen patients had recent major cardiovascular procedures.
4.  Some enrolled patients may have a long hospital stay, even some may be more than 30 days.
So would the in-hospital mortality other than the overall 30-day mortality reflect the real-world
perioperative data?
5.  Would the author can introduce more perioperative details for us, including the arrythmia,
anastomosis leakage, and length of stay? How many patients underwent one-stage anastomosis
and how many patient do not underwent anastomosis? How may patients underwent
postoperative bleeding which needed extra operation? Are there any patients suffer from
postoperative bleeding of important organs?
6. Would the author tell us the indication to administrate the enoxaparin?
7. There were so many confounding factors. It is hard to draw the conclusion that the
postoperative parenteral anticoagulants would benefit the patients, just by multivariate analysis.
assistant