Reviewer's report
Title:Contrast enhanced ultrasound findings in Peripheral Anaplastic T Cell
Lymphoma, revealed as Cavitating Mesenteric Lymph Node Syndrom in Celiac
Disease
Version: 1Date:31 August 2012
Reviewer: Paul J Ciclitira
Reviewer's report:
Cavitating lymph nodes are recognised complications of celiac disease. Thus this
is neither an unique or novel case. This is considered to be part of the
development of a T-cell lymphoma complicating celiac disease.
The title and content of the manuscript centres around the use of contrast
enhanced ultrasound findings in peripheral anaplastic T cell lymphoma. This
involves Cavitating mesenteric lymph node syndrome in celiac disease. The
focus of the manuscript is the use of contrast enhanced ultrasound. The
investigation failed to provide a diagnosis in this case. Thus the novel
investigation has not served any useful purpose. Thus, this is in turn a negative
result for the use of a novel type of imaging. I suggest that this description of a
novel type of imaging, that is contrast enhanced ultrasound has failed to provide
a valuable use for this investigation in this and therefore in further cases. In my
opinion the case report therefore fails to provide an improved method of
diagnosis in this and thus in turn further cases. To answer your specific question
the case report fails to provide any evidence for improved diagnosis using this
technique. I personally do not believe the case report warrants publication as it
has described an unusual but recognised complication of celiac disease for
which the new method of imaging has failed to serve any practical value.
Reviewer's report
Title:Contrast enhanced ultrasound findings in Peripheral Anaplastic T Cell
Lymphoma, revealed as Cavitating Mesenteric Lymph Node Syndrom in Celiac
Disease
Version: 1Date:31 August 2012
Reviewer: Paul J Ciclitira
Reviewer's report:
Cavitating lymph nodes are recognised complications of celiac disease. Thus this
is neither an unique or novel case. This is considered to be part of the
development of a T-cell lymphoma complicating celiac disease.
The title and content of the manuscript centres around the use of contrast
enhanced ultrasound findings in peripheral anaplastic T cell lymphoma. This
involves Cavitating mesenteric lymph node syndrome in celiac disease. The
focus of the manuscript is the use of contrast enhanced ultrasound. The
investigation failed to provide a diagnosis in this case. Thus the novel
investigation has not served any useful purpose. Thus, this is in turn a negative
result for the use of a novel type of imaging. I suggest that this description of a
novel type of imaging, that is contrast enhanced ultrasound has failed to provide
a valuable use for this investigation in this and therefore in further cases. In my
opinion the case report therefore fails to provide an improved method of
diagnosis in this and thus in turn further cases. To answer your specific question
the case report fails to provide any evidence for improved diagnosis using this
technique. I personally do not believe the case report warrants publication as it
has described an unusual but recognised complication of celiac disease for
which the new method of imaging has failed to serve any practical value.
Please review this paper.
user
Reviewer's report
Title:Contrast enhanced ultrasound findings in Peripheral Anaplastic T Cell
Lymphoma, revealed as Cavitating Mesenteric Lymph Node Syndrom in Celiac
Disease
Version: 1Date:31 August 2012
Reviewer: Paul J Ciclitira
Reviewer's report:
Cavitating lymph nodes are recognised complications of celiac disease. Thus this
is neither an unique or novel case. This is considered to be part of the
development of a T-cell lymphoma complicating celiac disease.
The title and content of the manuscript centres around the use of contrast
enhanced ultrasound findings in peripheral anaplastic T cell lymphoma. This
involves Cavitating mesenteric lymph node syndrome in celiac disease. The
focus of the manuscript is the use of contrast enhanced ultrasound. The
investigation failed to provide a diagnosis in this case. Thus the novel
investigation has not served any useful purpose. Thus, this is in turn a negative
result for the use of a novel type of imaging. I suggest that this description of a
novel type of imaging, that is contrast enhanced ultrasound has failed to provide
a valuable use for this investigation in this and therefore in further cases. In my
opinion the case report therefore fails to provide an improved method of
diagnosis in this and thus in turn further cases. To answer your specific question
the case report fails to provide any evidence for improved diagnosis using this
technique. I personally do not believe the case report warrants publication as it
has described an unusual but recognised complication of celiac disease for
which the new method of imaging has failed to serve any practical value.
assistant