Title:  Development and clinical validation of deep learning-based Immunohistochemistry
prediction models for subtyping and staging of gastrointestinal cancers
Version: 5 Date: 02 May 2025
Reviewer's report:
I would like to thank the authors for their response to each comment. Modifications done to the
manuscript made it clear and suitable for publication.
However  (Table 2. The baseline of MRMC) needs to re-revised. the site of biopsy of specimen
30 is mentioned to be rectal despite that diagnosis is non atrophic gastritis. the same is in
specimens  7,11,16 are mentioned to be esophageal biopsy while they are diagnosed as gastritis.
Title:  Development and clinical validation of deep learning-based Immunohistochemistry
prediction models for subtyping and staging of gastrointestinal cancers
Version: 5 Date: 02 May 2025
Reviewer's report:
I would like to thank the authors for their response to each comment. Modifications done to the
manuscript made it clear and suitable for publication.
However  (Table 2. The baseline of MRMC) needs to re-revised. the site of biopsy of specimen
30 is mentioned to be rectal despite that diagnosis is non atrophic gastritis. the same is in
specimens  7,11,16 are mentioned to be esophageal biopsy while they are diagnosed as gastritis.
Please review this paper.
user
Title:  Development and clinical validation of deep learning-based Immunohistochemistry
prediction models for subtyping and staging of gastrointestinal cancers
Version: 5 Date: 02 May 2025
Reviewer's report:
I would like to thank the authors for their response to each comment. Modifications done to the
manuscript made it clear and suitable for publication.
However  (Table 2. The baseline of MRMC) needs to re-revised. the site of biopsy of specimen
30 is mentioned to be rectal despite that diagnosis is non atrophic gastritis. the same is in
specimens  7,11,16 are mentioned to be esophageal biopsy while they are diagnosed as gastritis.
assistant