Reviewer's report
Title:A comparison of four fibrosis indexes in chronic HCV: Development of new
fibrosis-cirrhosis index (FCI)
Version: 2Date:17 March 2011
Reviewer: Ned Snyder
Reviewer's report:
Major Compulsory Revisions:
The authors have adequately addressed my concerns in questions 1,2,4, and 5.
In question 3, I expressed my concern about the relatively high mean values for
the APRI and FIB-4 in Fo-F1 patients as compared to previous reports. While the
authors usefully reply that this has been reported in other studies from the region,
I do not follow their statement that this might reflect "geographical variation in the
seroprevalence of HCV". This needs to be clarified or omitted.
Minor Essential Revisions:Inthe formula for the FIB-4 the ALT is to the 1/2 power
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests
Reviewer's report
Title:A comparison of four fibrosis indexes in chronic HCV: Development of new
fibrosis-cirrhosis index (FCI)
Version: 2Date:17 March 2011
Reviewer: Ned Snyder
Reviewer's report:
Major Compulsory Revisions:
The authors have adequately addressed my concerns in questions 1,2,4, and 5.
In question 3, I expressed my concern about the relatively high mean values for
the APRI and FIB-4 in Fo-F1 patients as compared to previous reports. While the
authors usefully reply that this has been reported in other studies from the region,
I do not follow their statement that this might reflect "geographical variation in the
seroprevalence of HCV". This needs to be clarified or omitted.
Minor Essential Revisions:Inthe formula for the FIB-4 the ALT is to the 1/2 power
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests
Please review this paper.
user
Reviewer's report
Title:A comparison of four fibrosis indexes in chronic HCV: Development of new
fibrosis-cirrhosis index (FCI)
Version: 2Date:17 March 2011
Reviewer: Ned Snyder
Reviewer's report:
Major Compulsory Revisions:
The authors have adequately addressed my concerns in questions 1,2,4, and 5.
In question 3, I expressed my concern about the relatively high mean values for
the APRI and FIB-4 in Fo-F1 patients as compared to previous reports. While the
authors usefully reply that this has been reported in other studies from the region,
I do not follow their statement that this might reflect "geographical variation in the
seroprevalence of HCV". This needs to be clarified or omitted.
Minor Essential Revisions:Inthe formula for the FIB-4 the ALT is to the 1/2 power
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests
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