Reviewer's report
Title:Effects of paracentesis on hemodynamic parameters and respiratory
function in critically ill patients
Version:1Date:1 November 2013
Reviewer: Alexander Koch
Reviewer's report:
Phillip an collegues report on the "Effects of paracentesis on hemodynamic
parameters and respiratory function in critically ill patients". Main findings are that
paracentesis in critically ill patients is safe regarding hemodynamic
function, renal function and intervention-related complications. Paracentesis in
critically ill and mechanically ventilated patients results in immediate and
sustained improvement of respiratory function. The manuscript is well written and
data presentation is sound. A highlight of the study is the thorough analysis of
multiple cardiovascular and pulmonary parameters. The authors accurately
mention the limitations of thir study. Nevertheless, i have some minor remarks:
1. The backgroud section should be more focused on ICU patients.
2. the fact that albumin substitution was at the discretion of the treating ICU
physician and was not performed following national/international guidelines
should be adressed in the limitations section.
3. it would be very interesting, if the authors would present data on serum
albumin/protein levels before and after paracentesis.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
I declare that I have no competing interests
Reviewer's report
Title:Effects of paracentesis on hemodynamic parameters and respiratory
function in critically ill patients
Version:1Date:1 November 2013
Reviewer: Alexander Koch
Reviewer's report:
Phillip an collegues report on the "Effects of paracentesis on hemodynamic
parameters and respiratory function in critically ill patients". Main findings are that
paracentesis in critically ill patients is safe regarding hemodynamic
function, renal function and intervention-related complications. Paracentesis in
critically ill and mechanically ventilated patients results in immediate and
sustained improvement of respiratory function. The manuscript is well written and
data presentation is sound. A highlight of the study is the thorough analysis of
multiple cardiovascular and pulmonary parameters. The authors accurately
mention the limitations of thir study. Nevertheless, i have some minor remarks:
1. The backgroud section should be more focused on ICU patients.
2. the fact that albumin substitution was at the discretion of the treating ICU
physician and was not performed following national/international guidelines
should be adressed in the limitations section.
3. it would be very interesting, if the authors would present data on serum
albumin/protein levels before and after paracentesis.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
I declare that I have no competing interests
Please review this paper.
user
Reviewer's report
Title:Effects of paracentesis on hemodynamic parameters and respiratory
function in critically ill patients
Version:1Date:1 November 2013
Reviewer: Alexander Koch
Reviewer's report:
Phillip an collegues report on the "Effects of paracentesis on hemodynamic
parameters and respiratory function in critically ill patients". Main findings are that
paracentesis in critically ill patients is safe regarding hemodynamic
function, renal function and intervention-related complications. Paracentesis in
critically ill and mechanically ventilated patients results in immediate and
sustained improvement of respiratory function. The manuscript is well written and
data presentation is sound. A highlight of the study is the thorough analysis of
multiple cardiovascular and pulmonary parameters. The authors accurately
mention the limitations of thir study. Nevertheless, i have some minor remarks:
1. The backgroud section should be more focused on ICU patients.
2. the fact that albumin substitution was at the discretion of the treating ICU
physician and was not performed following national/international guidelines
should be adressed in the limitations section.
3. it would be very interesting, if the authors would present data on serum
albumin/protein levels before and after paracentesis.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
I declare that I have no competing interests
assistant