Title: 7-Hydroxycoumarin ameliorates ulcerative colitis in mice by inhibiting the MAPK
pathway and alleviating gut microbiota dysbiosis
Version: 5 Date: 09 Aug 2024
Reviewer's report:
Useful scientific work and I have some suggestions to be your manuscript more clear and
interesting for readers:
#2.1 Succinctly state the DAI evaluation method.
#2.10 The 16S analysis needs to be expanded upon, there are many parameters in 16S analyses
and the reader is told limited sequencing method.
#3.1 Kindly make appropriate description of DAI. If applicable add in the section, the H&E
score, or mark out colonic crypts and epithelial cells with arrows in Figure 1F.
#3.5.5 It is difficult to draw conclusions of PCoA and NMDS. Suggest accurate representation.
#Improve the discussion section.
#Abbreviations of the same word are found both in the methods and results paragraphs. I also
found some editing errors in the manuscript. Kindly revised the manuscript carefully.
Title: 7-Hydroxycoumarin ameliorates ulcerative colitis in mice by inhibiting the MAPK
pathway and alleviating gut microbiota dysbiosis
Version: 5 Date: 09 Aug 2024
Reviewer's report:
Useful scientific work and I have some suggestions to be your manuscript more clear and
interesting for readers:
#2.1 Succinctly state the DAI evaluation method.
#2.10 The 16S analysis needs to be expanded upon, there are many parameters in 16S analyses
and the reader is told limited sequencing method.
#3.1 Kindly make appropriate description of DAI. If applicable add in the section, the H&E
score, or mark out colonic crypts and epithelial cells with arrows in Figure 1F.
#3.5.5 It is difficult to draw conclusions of PCoA and NMDS. Suggest accurate representation.
#Improve the discussion section.
#Abbreviations of the same word are found both in the methods and results paragraphs. I also
found some editing errors in the manuscript. Kindly revised the manuscript carefully.
Please review this paper.
user
Title: 7-Hydroxycoumarin ameliorates ulcerative colitis in mice by inhibiting the MAPK
pathway and alleviating gut microbiota dysbiosis
Version: 5 Date: 09 Aug 2024
Reviewer's report:
Useful scientific work and I have some suggestions to be your manuscript more clear and
interesting for readers:
#2.1 Succinctly state the DAI evaluation method.
#2.10 The 16S analysis needs to be expanded upon, there are many parameters in 16S analyses
and the reader is told limited sequencing method.
#3.1 Kindly make appropriate description of DAI. If applicable add in the section, the H&E
score, or mark out colonic crypts and epithelial cells with arrows in Figure 1F.
#3.5.5 It is difficult to draw conclusions of PCoA and NMDS. Suggest accurate representation.
#Improve the discussion section.
#Abbreviations of the same word are found both in the methods and results paragraphs. I also
found some editing errors in the manuscript. Kindly revised the manuscript carefully.
assistant