Reviewer's report
Title:Deficiency in four and one half LIM domain protein 2 (FHL2) aggravates
liver fibrosis in mice
Version: 1Date:29 August 2012
Reviewer: Pao-Hsien Chu
Reviewer's report:
FHL2-/- and wild type (wt) mice were challenged with CCl4. Fibrotic response
was qualified by qRT-PCR and IHC. FHL2 was strongly expressed in the
myofibroblasts of fibrotic human livers.
1. The major concern is without mechanism. Please provide some direct linkage
of interaction proteins or possible treatment effects.
2. The Englich writing needs to improved lots.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
Nil.
Reviewer's report
Title:Deficiency in four and one half LIM domain protein 2 (FHL2) aggravates
liver fibrosis in mice
Version: 1Date:29 August 2012
Reviewer: Pao-Hsien Chu
Reviewer's report:
FHL2-/- and wild type (wt) mice were challenged with CCl4. Fibrotic response
was qualified by qRT-PCR and IHC. FHL2 was strongly expressed in the
myofibroblasts of fibrotic human livers.
1. The major concern is without mechanism. Please provide some direct linkage
of interaction proteins or possible treatment effects.
2. The Englich writing needs to improved lots.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
Nil.
Please review this paper.
user
Reviewer's report
Title:Deficiency in four and one half LIM domain protein 2 (FHL2) aggravates
liver fibrosis in mice
Version: 1Date:29 August 2012
Reviewer: Pao-Hsien Chu
Reviewer's report:
FHL2-/- and wild type (wt) mice were challenged with CCl4. Fibrotic response
was qualified by qRT-PCR and IHC. FHL2 was strongly expressed in the
myofibroblasts of fibrotic human livers.
1. The major concern is without mechanism. Please provide some direct linkage
of interaction proteins or possible treatment effects.
2. The Englich writing needs to improved lots.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
Nil.
assistant