Title: Association between body roundness index (BRI) and gallstones: results of the 2017-2020
National Health and Nutrition Examination Survey (NHANES)
Version: 1 Date: 17 May 2024
Reviewer:  Anwar Abouelnasr
Reviewer's report:
Dear Authors, please see my comments and edits below
-In the section on the baseline characteristics of participants, it is noted that the dietary
information collected included details on energy, sugar, and fat. However, it is crucial to
determine whether additional dietary factors such as water intake, dietary fiber, caffeine
consumption, and alcohol consumption were also documented and analyzed as part of the dietary
information.
-With respect to limitations, it is acknowledged that despite the consideration of several pertinent
variables, the complete elimination of confounding factors poses a significant challenge.
Therefore, it is essential to exercise prudence when interpreting the conclusion, and this
cautionary note should be explicitly elucidated within the limitations section of the study.
-In the discussion of covariates, it is important to address the absence of information concerning
participants' medication use. Notably, certain medications, including estrogen, progesterone,
and octreotide, are known to predispose individuals to gallstones. The failure to account for
the potential impact of medication use represents a noteworthy limitation that should be duly
acknowledged or included within the study's limitations.
-Furthermore, it is suggested that the potential influence of the body roundness index on
gallstone formation may be attributed to hormonal levels. Therefore, conducting further research
to explore this potential connection and integrating relevant findings into the study is advisable.
Title: Association between body roundness index (BRI) and gallstones: results of the 2017-2020
National Health and Nutrition Examination Survey (NHANES)
Version: 1 Date: 17 May 2024
Reviewer:  Anwar Abouelnasr
Reviewer's report:
Dear Authors, please see my comments and edits below
-In the section on the baseline characteristics of participants, it is noted that the dietary
information collected included details on energy, sugar, and fat. However, it is crucial to
determine whether additional dietary factors such as water intake, dietary fiber, caffeine
consumption, and alcohol consumption were also documented and analyzed as part of the dietary
information.
-With respect to limitations, it is acknowledged that despite the consideration of several pertinent
variables, the complete elimination of confounding factors poses a significant challenge.
Therefore, it is essential to exercise prudence when interpreting the conclusion, and this
cautionary note should be explicitly elucidated within the limitations section of the study.
-In the discussion of covariates, it is important to address the absence of information concerning
participants' medication use. Notably, certain medications, including estrogen, progesterone,
and octreotide, are known to predispose individuals to gallstones. The failure to account for
the potential impact of medication use represents a noteworthy limitation that should be duly
acknowledged or included within the study's limitations.
-Furthermore, it is suggested that the potential influence of the body roundness index on
gallstone formation may be attributed to hormonal levels. Therefore, conducting further research
to explore this potential connection and integrating relevant findings into the study is advisable.
Please review this paper.
user
Title: Association between body roundness index (BRI) and gallstones: results of the 2017-2020
National Health and Nutrition Examination Survey (NHANES)
Version: 1 Date: 17 May 2024
Reviewer:  Anwar Abouelnasr
Reviewer's report:
Dear Authors, please see my comments and edits below
-In the section on the baseline characteristics of participants, it is noted that the dietary
information collected included details on energy, sugar, and fat. However, it is crucial to
determine whether additional dietary factors such as water intake, dietary fiber, caffeine
consumption, and alcohol consumption were also documented and analyzed as part of the dietary
information.
-With respect to limitations, it is acknowledged that despite the consideration of several pertinent
variables, the complete elimination of confounding factors poses a significant challenge.
Therefore, it is essential to exercise prudence when interpreting the conclusion, and this
cautionary note should be explicitly elucidated within the limitations section of the study.
-In the discussion of covariates, it is important to address the absence of information concerning
participants' medication use. Notably, certain medications, including estrogen, progesterone,
and octreotide, are known to predispose individuals to gallstones. The failure to account for
the potential impact of medication use represents a noteworthy limitation that should be duly
acknowledged or included within the study's limitations.
-Furthermore, it is suggested that the potential influence of the body roundness index on
gallstone formation may be attributed to hormonal levels. Therefore, conducting further research
to explore this potential connection and integrating relevant findings into the study is advisable.
assistant