Title: Primary Liver Cancer Disease Burden in Cambodia During 1990-2021: A Systematic
Analysis of Datasets from the Global Burden of Disease Study 2021
Version: 1 Date: 31 Mar 2025
Reviewer:  Hengliang Lv
Reviewer's report:
1.The description of the statistical methods is too brief. The calculation formula of EAPC
should be provided. The ARIMA model is generally used for short-term forecasting, and its
performance in long-term forecasting is not good. As can be seen from the results of this
manuscript, the forecasting effect is not satisfactory. Moreover, in the results, I did not find
any quantitative results regarding the predictions. It is recommended that the author delete the
predictive content and revise the entire manuscript, including the abstract.
2. This manuscript  analyzed the risk factors of liver cancer. It is recommended that in the
discussion section, control measures at the front end of the causal chain be proposed in response
to these risk factors.
Title: Primary Liver Cancer Disease Burden in Cambodia During 1990-2021: A Systematic
Analysis of Datasets from the Global Burden of Disease Study 2021
Version: 1 Date: 31 Mar 2025
Reviewer:  Hengliang Lv
Reviewer's report:
1.The description of the statistical methods is too brief. The calculation formula of EAPC
should be provided. The ARIMA model is generally used for short-term forecasting, and its
performance in long-term forecasting is not good. As can be seen from the results of this
manuscript, the forecasting effect is not satisfactory. Moreover, in the results, I did not find
any quantitative results regarding the predictions. It is recommended that the author delete the
predictive content and revise the entire manuscript, including the abstract.
2. This manuscript  analyzed the risk factors of liver cancer. It is recommended that in the
discussion section, control measures at the front end of the causal chain be proposed in response
to these risk factors.
Please review this paper.
user
Title: Primary Liver Cancer Disease Burden in Cambodia During 1990-2021: A Systematic
Analysis of Datasets from the Global Burden of Disease Study 2021
Version: 1 Date: 31 Mar 2025
Reviewer:  Hengliang Lv
Reviewer's report:
1.The description of the statistical methods is too brief. The calculation formula of EAPC
should be provided. The ARIMA model is generally used for short-term forecasting, and its
performance in long-term forecasting is not good. As can be seen from the results of this
manuscript, the forecasting effect is not satisfactory. Moreover, in the results, I did not find
any quantitative results regarding the predictions. It is recommended that the author delete the
predictive content and revise the entire manuscript, including the abstract.
2. This manuscript  analyzed the risk factors of liver cancer. It is recommended that in the
discussion section, control measures at the front end of the causal chain be proposed in response
to these risk factors.
assistant