Title: Alcohol increases treatment failure for Helicobacter pylori eradication in Asian
populations
Version: 1 Date: 01 Feb 2023
Reviewer's report:
Dear Dr. Wang,
Thank you for your efforts in the field of the relationship between alcohol consumption and the
failure of H. pylori eradication. The results of this meta-analysis are interesting. My comments
for this article were listed below
1. Among 7 studies in the subgroup analysis, table 3, the amount of ethanol drinking
was to define the alcohol consumption. Therefore, the interpretation of the meta-analysis might
be incorrect. In the three studies that defined alcohol consumption as >80g of ethanol drinking,
the failure of H. pylori eradication was associated with alcohol consumption. On the other hand,
in the rest four studies that defined alcohol consumption as < 40g of ethanol drinking, the
eradication rate was not affected by ethanol. However, we could not make the conclusion that
higher alcohol consumption would be associated with lower efficacy of eradication.
2. English editing is suggested due to some typos are found.
Title: Alcohol increases treatment failure for Helicobacter pylori eradication in Asian
populations
Version: 1 Date: 01 Feb 2023
Reviewer's report:
Dear Dr. Wang,
Thank you for your efforts in the field of the relationship between alcohol consumption and the
failure of H. pylori eradication. The results of this meta-analysis are interesting. My comments
for this article were listed below
1. Among 7 studies in the subgroup analysis, table 3, the amount of ethanol drinking
was to define the alcohol consumption. Therefore, the interpretation of the meta-analysis might
be incorrect. In the three studies that defined alcohol consumption as >80g of ethanol drinking,
the failure of H. pylori eradication was associated with alcohol consumption. On the other hand,
in the rest four studies that defined alcohol consumption as < 40g of ethanol drinking, the
eradication rate was not affected by ethanol. However, we could not make the conclusion that
higher alcohol consumption would be associated with lower efficacy of eradication.
2. English editing is suggested due to some typos are found.
Please review this paper.
user
Title: Alcohol increases treatment failure for Helicobacter pylori eradication in Asian
populations
Version: 1 Date: 01 Feb 2023
Reviewer's report:
Dear Dr. Wang,
Thank you for your efforts in the field of the relationship between alcohol consumption and the
failure of H. pylori eradication. The results of this meta-analysis are interesting. My comments
for this article were listed below
1. Among 7 studies in the subgroup analysis, table 3, the amount of ethanol drinking
was to define the alcohol consumption. Therefore, the interpretation of the meta-analysis might
be incorrect. In the three studies that defined alcohol consumption as >80g of ethanol drinking,
the failure of H. pylori eradication was associated with alcohol consumption. On the other hand,
in the rest four studies that defined alcohol consumption as < 40g of ethanol drinking, the
eradication rate was not affected by ethanol. However, we could not make the conclusion that
higher alcohol consumption would be associated with lower efficacy of eradication.
2. English editing is suggested due to some typos are found.
assistant