Title: The Diagnostic Criteria for Psychosomatic Research-Revised (DCPR-R) in a National
China Multicenter Cohort of Patients with Irritable Bowel Syndrome and Overlapping
Gastroesophageal Reflux Disease
Version: 2 Date: 20 Jan 2025
Reviewer's report:
This study analyzed the prevalence of DCPR-R psychosomatic syndrome in patients with IBS
alone and IBS+GERD from 20 hospitals, as well as the correlation between DCPR-R and some
other commonly used psychological assessment tools in clinical practice.
Since I'm not an expert in the psychiatric/psychological field, from the perspective of a doctor
who studies functional gastrointestinal disorders, I would like to make a few suggestions/
questions:
1.The hospitals in this study include: 9 hospitals in the eastern region, 2 hospitals in the
northeast, 5 hospitals in the central region, and 4 hospitals in the western region. Have regional
socio-economic and environmental differences been taken into account? Why not nationwide
coverage? Why was the number of hospitals uneven across regions?
2.There was a difference in age between patients with IBS and IBS+GERD, and the following
results suggested that age was a risk factor for DCRP-R>1 in patients with IBS only. It could be
seen that age might be a confounding factor. Some statistical methods can be considered to make
no significant difference in baseline information between groups and reduce the interference of
confounding factors.
3.Is DCPR-R a widely accepted diagnostic criterion? There was no significant correlation
between most of the currently commonly used assessment scales and DCPR-R (multivariate
analysis in table 3 and 4), which one should be believed to be authoritative (DCPR-R or other
scales)? Why did you choose this diagnostic criterion?
4.You said that this study explored the utility of DCPR-R in distinguishing psychosomatic
symptoms in functional gastrointestinal disorders with comorbid syndromes. Were other
functional disease phenotypes used to validate the suitability of the diagnostic tool (DCPR-R)?
Title: The Diagnostic Criteria for Psychosomatic Research-Revised (DCPR-R) in a National
China Multicenter Cohort of Patients with Irritable Bowel Syndrome and Overlapping
Gastroesophageal Reflux Disease
Version: 2 Date: 20 Jan 2025
Reviewer's report:
This study analyzed the prevalence of DCPR-R psychosomatic syndrome in patients with IBS
alone and IBS+GERD from 20 hospitals, as well as the correlation between DCPR-R and some
other commonly used psychological assessment tools in clinical practice.
Since I'm not an expert in the psychiatric/psychological field, from the perspective of a doctor
who studies functional gastrointestinal disorders, I would like to make a few suggestions/
questions:
1.The hospitals in this study include: 9 hospitals in the eastern region, 2 hospitals in the
northeast, 5 hospitals in the central region, and 4 hospitals in the western region. Have regional
socio-economic and environmental differences been taken into account? Why not nationwide
coverage? Why was the number of hospitals uneven across regions?
2.There was a difference in age between patients with IBS and IBS+GERD, and the following
results suggested that age was a risk factor for DCRP-R>1 in patients with IBS only. It could be
seen that age might be a confounding factor. Some statistical methods can be considered to make
no significant difference in baseline information between groups and reduce the interference of
confounding factors.
3.Is DCPR-R a widely accepted diagnostic criterion? There was no significant correlation
between most of the currently commonly used assessment scales and DCPR-R (multivariate
analysis in table 3 and 4), which one should be believed to be authoritative (DCPR-R or other
scales)? Why did you choose this diagnostic criterion?
4.You said that this study explored the utility of DCPR-R in distinguishing psychosomatic
symptoms in functional gastrointestinal disorders with comorbid syndromes. Were other
functional disease phenotypes used to validate the suitability of the diagnostic tool (DCPR-R)?
Please review this paper.
user
Title: The Diagnostic Criteria for Psychosomatic Research-Revised (DCPR-R) in a National
China Multicenter Cohort of Patients with Irritable Bowel Syndrome and Overlapping
Gastroesophageal Reflux Disease
Version: 2 Date: 20 Jan 2025
Reviewer's report:
This study analyzed the prevalence of DCPR-R psychosomatic syndrome in patients with IBS
alone and IBS+GERD from 20 hospitals, as well as the correlation between DCPR-R and some
other commonly used psychological assessment tools in clinical practice.
Since I'm not an expert in the psychiatric/psychological field, from the perspective of a doctor
who studies functional gastrointestinal disorders, I would like to make a few suggestions/
questions:
1.The hospitals in this study include: 9 hospitals in the eastern region, 2 hospitals in the
northeast, 5 hospitals in the central region, and 4 hospitals in the western region. Have regional
socio-economic and environmental differences been taken into account? Why not nationwide
coverage? Why was the number of hospitals uneven across regions?
2.There was a difference in age between patients with IBS and IBS+GERD, and the following
results suggested that age was a risk factor for DCRP-R>1 in patients with IBS only. It could be
seen that age might be a confounding factor. Some statistical methods can be considered to make
no significant difference in baseline information between groups and reduce the interference of
confounding factors.
3.Is DCPR-R a widely accepted diagnostic criterion? There was no significant correlation
between most of the currently commonly used assessment scales and DCPR-R (multivariate
analysis in table 3 and 4), which one should be believed to be authoritative (DCPR-R or other
scales)? Why did you choose this diagnostic criterion?
4.You said that this study explored the utility of DCPR-R in distinguishing psychosomatic
symptoms in functional gastrointestinal disorders with comorbid syndromes. Were other
functional disease phenotypes used to validate the suitability of the diagnostic tool (DCPR-R)?
assistant