Reviewer's report
Title:High mortality of pneumonia in cirrhotic patients with ascites
Version: 2Date:27 December 2012
Reviewer: Tony Bruns
Reviewer's report:
In their revision, the authors clarify some important points raised and improved
the value of the manuscript (Points 1a, 1b).
In their point-to-point responses, the authors acknowledge that the following data
are important to interpret the results and confounders: MELD score, causes of
death, type of pneumonia (CAP, HAP, VAP), presence of SIRS, ICU-treatment,
penumonia severity scores (Points 2a-d). However, their method of data
acquisition (retrospective ICD-based study) does not allow to incorporate these
data.
Furthermore, microbiological data are not available and, therefore,
recommendations regarding prophylaxis (vaccination) or empiric treatment
cannot be drawn.
Major Compulsory Revisions
1) English grammar is poor throughout the manuscript. I would advice a
professional language editing service prior to publication.
2) Please indicate the limitations of the study (see Points 2a-d and above) in the
manuscript.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests
Reviewer's report
Title:High mortality of pneumonia in cirrhotic patients with ascites
Version: 2Date:27 December 2012
Reviewer: Tony Bruns
Reviewer's report:
In their revision, the authors clarify some important points raised and improved
the value of the manuscript (Points 1a, 1b).
In their point-to-point responses, the authors acknowledge that the following data
are important to interpret the results and confounders: MELD score, causes of
death, type of pneumonia (CAP, HAP, VAP), presence of SIRS, ICU-treatment,
penumonia severity scores (Points 2a-d). However, their method of data
acquisition (retrospective ICD-based study) does not allow to incorporate these
data.
Furthermore, microbiological data are not available and, therefore,
recommendations regarding prophylaxis (vaccination) or empiric treatment
cannot be drawn.
Major Compulsory Revisions
1) English grammar is poor throughout the manuscript. I would advice a
professional language editing service prior to publication.
2) Please indicate the limitations of the study (see Points 2a-d and above) in the
manuscript.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests
Please review this paper.
user
Reviewer's report
Title:High mortality of pneumonia in cirrhotic patients with ascites
Version: 2Date:27 December 2012
Reviewer: Tony Bruns
Reviewer's report:
In their revision, the authors clarify some important points raised and improved
the value of the manuscript (Points 1a, 1b).
In their point-to-point responses, the authors acknowledge that the following data
are important to interpret the results and confounders: MELD score, causes of
death, type of pneumonia (CAP, HAP, VAP), presence of SIRS, ICU-treatment,
penumonia severity scores (Points 2a-d). However, their method of data
acquisition (retrospective ICD-based study) does not allow to incorporate these
data.
Furthermore, microbiological data are not available and, therefore,
recommendations regarding prophylaxis (vaccination) or empiric treatment
cannot be drawn.
Major Compulsory Revisions
1) English grammar is poor throughout the manuscript. I would advice a
professional language editing service prior to publication.
2) Please indicate the limitations of the study (see Points 2a-d and above) in the
manuscript.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests
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