Title: Development of a Novel Immune-Related lncRNA Prognostic Signature for Patients with
Hepatocellular Carcinoma
Version: 3 Date: 24 Jul 2022
Reviewer's report:
In this manuscript, the authors screened immune-related long non-coding RNAs (IncRNAs) to
evaluate whether to affect the prognosis of the patients with hepatocellular carcinoma. As a
result, they identified the several prognostic biomarkers. The method was simple and has been
well established, and the manuscript is well written. Please consider some concerns with regard
to the following points.
We need the information about the patients in detail because the several prognostic factors have
been identified in addition to age, gender, stage, and grade. Otherwise, the prognostic value of
these IncRNAs as prognostic factors is unclear.
The factors identified in this study are those that influence patient prognosis. Of more interest
is whether they are predictive of response to immunotherapy.
Title: Development of a Novel Immune-Related lncRNA Prognostic Signature for Patients with
Hepatocellular Carcinoma
Version: 3 Date: 24 Jul 2022
Reviewer's report:
In this manuscript, the authors screened immune-related long non-coding RNAs (IncRNAs) to
evaluate whether to affect the prognosis of the patients with hepatocellular carcinoma. As a
result, they identified the several prognostic biomarkers. The method was simple and has been
well established, and the manuscript is well written. Please consider some concerns with regard
to the following points.
We need the information about the patients in detail because the several prognostic factors have
been identified in addition to age, gender, stage, and grade. Otherwise, the prognostic value of
these IncRNAs as prognostic factors is unclear.
The factors identified in this study are those that influence patient prognosis. Of more interest
is whether they are predictive of response to immunotherapy.
Please review this paper.
user
Title: Development of a Novel Immune-Related lncRNA Prognostic Signature for Patients with
Hepatocellular Carcinoma
Version: 3 Date: 24 Jul 2022
Reviewer's report:
In this manuscript, the authors screened immune-related long non-coding RNAs (IncRNAs) to
evaluate whether to affect the prognosis of the patients with hepatocellular carcinoma. As a
result, they identified the several prognostic biomarkers. The method was simple and has been
well established, and the manuscript is well written. Please consider some concerns with regard
to the following points.
We need the information about the patients in detail because the several prognostic factors have
been identified in addition to age, gender, stage, and grade. Otherwise, the prognostic value of
these IncRNAs as prognostic factors is unclear.
The factors identified in this study are those that influence patient prognosis. Of more interest
is whether they are predictive of response to immunotherapy.
assistant