Title: Predicting Cholangiocarcinoma in Primary Sclerosing Cholangitis: Using Artificial
Intelligence, Clinical and Laboratory Data
Version: 6 Date: 23 Mar 2023
Reviewer's report:
Line_43, AI-based model better than statistical models? The reviewer regards statistical methods
(CoxPH) that the authors used as a broadly defined AI.
Line_382, the adjective 'large' is not necessary.
Line_101~103, the sentence is complicated and not friendly to readers.
In Line_191 and line_219, the sentences 'patients without IBD diagnosis were set IBD duration
as 0 years.' are repetitive.  The author should clarify when a PSC patient without IBD entered this
cohort, the IBD duration was zero. Was the IBD duration increasing when the study proceeded?
For example, the  IBD duration is 3 in the third year when a patient without IBD entered the
study.
Title: Predicting Cholangiocarcinoma in Primary Sclerosing Cholangitis: Using Artificial
Intelligence, Clinical and Laboratory Data
Version: 6 Date: 23 Mar 2023
Reviewer's report:
Line_43, AI-based model better than statistical models? The reviewer regards statistical methods
(CoxPH) that the authors used as a broadly defined AI.
Line_382, the adjective 'large' is not necessary.
Line_101~103, the sentence is complicated and not friendly to readers.
In Line_191 and line_219, the sentences 'patients without IBD diagnosis were set IBD duration
as 0 years.' are repetitive.  The author should clarify when a PSC patient without IBD entered this
cohort, the IBD duration was zero. Was the IBD duration increasing when the study proceeded?
For example, the  IBD duration is 3 in the third year when a patient without IBD entered the
study.
Please review this paper.
user
Title: Predicting Cholangiocarcinoma in Primary Sclerosing Cholangitis: Using Artificial
Intelligence, Clinical and Laboratory Data
Version: 6 Date: 23 Mar 2023
Reviewer's report:
Line_43, AI-based model better than statistical models? The reviewer regards statistical methods
(CoxPH) that the authors used as a broadly defined AI.
Line_382, the adjective 'large' is not necessary.
Line_101~103, the sentence is complicated and not friendly to readers.
In Line_191 and line_219, the sentences 'patients without IBD diagnosis were set IBD duration
as 0 years.' are repetitive.  The author should clarify when a PSC patient without IBD entered this
cohort, the IBD duration was zero. Was the IBD duration increasing when the study proceeded?
For example, the  IBD duration is 3 in the third year when a patient without IBD entered the
study.
assistant