Title: 18 F-FDG PET/CT metabolic parameters may have predictive value for relapse of type
1 autoimmune pancreatitis
Version: 4 Date: 11 Dec 2023
Reviewer's report:
Thank you for submitting the revision.
Despite the improvements made, further clarifications are still required.
A. Methods
a) Study subjects: do you mean not receiving maintenance therapy after remission, rather than
not receiving maintenance at all (i.e. after initial steroid induction phase)? as this statment of
not receiving maintenance therpy is contradictory to Results section p.7 line 188-191. Please
revise accordingly.
B. Results section
a). p. 6 line 181: please change "The median recurrence time of the relapsed group" to "The
median time to recurrence...."
b) What is the time between PET to initiation of steroid therapy  of the entire cohort? Please
add the information to the results section.
C. Tables
a) Table 3: for better reporting the ORs, please provide reference category for each parameter
in the table (an example can be found at the following link:  https://kjronline.org/DOIx.php?
id=10.3348/kjr.2022.0249).
b) Table 1: please add the definition of "lose weight" to the footnote.
D. Title
While the combination of IgG4 and TLG2.5 appears to more accurately predict patient relapse,
the ORs are not particularly strong, and the model's sensitivity and specificity are only
moderately effective. Therefore, I recommend opting for a less definitive title for the manuscript.
Title: 18 F-FDG PET/CT metabolic parameters may have predictive value for relapse of type
1 autoimmune pancreatitis
Version: 4 Date: 11 Dec 2023
Reviewer's report:
Thank you for submitting the revision.
Despite the improvements made, further clarifications are still required.
A. Methods
a) Study subjects: do you mean not receiving maintenance therapy after remission, rather than
not receiving maintenance at all (i.e. after initial steroid induction phase)? as this statment of
not receiving maintenance therpy is contradictory to Results section p.7 line 188-191. Please
revise accordingly.
B. Results section
a). p. 6 line 181: please change "The median recurrence time of the relapsed group" to "The
median time to recurrence...."
b) What is the time between PET to initiation of steroid therapy  of the entire cohort? Please
add the information to the results section.
C. Tables
a) Table 3: for better reporting the ORs, please provide reference category for each parameter
in the table (an example can be found at the following link:  https://kjronline.org/DOIx.php?
id=10.3348/kjr.2022.0249).
b) Table 1: please add the definition of "lose weight" to the footnote.
D. Title
While the combination of IgG4 and TLG2.5 appears to more accurately predict patient relapse,
the ORs are not particularly strong, and the model's sensitivity and specificity are only
moderately effective. Therefore, I recommend opting for a less definitive title for the manuscript.
Please review this paper.
user
Title: 18 F-FDG PET/CT metabolic parameters may have predictive value for relapse of type
1 autoimmune pancreatitis
Version: 4 Date: 11 Dec 2023
Reviewer's report:
Thank you for submitting the revision.
Despite the improvements made, further clarifications are still required.
A. Methods
a) Study subjects: do you mean not receiving maintenance therapy after remission, rather than
not receiving maintenance at all (i.e. after initial steroid induction phase)? as this statment of
not receiving maintenance therpy is contradictory to Results section p.7 line 188-191. Please
revise accordingly.
B. Results section
a). p. 6 line 181: please change "The median recurrence time of the relapsed group" to "The
median time to recurrence...."
b) What is the time between PET to initiation of steroid therapy  of the entire cohort? Please
add the information to the results section.
C. Tables
a) Table 3: for better reporting the ORs, please provide reference category for each parameter
in the table (an example can be found at the following link:  https://kjronline.org/DOIx.php?
id=10.3348/kjr.2022.0249).
b) Table 1: please add the definition of "lose weight" to the footnote.
D. Title
While the combination of IgG4 and TLG2.5 appears to more accurately predict patient relapse,
the ORs are not particularly strong, and the model's sensitivity and specificity are only
moderately effective. Therefore, I recommend opting for a less definitive title for the manuscript.
assistant