Reviewer's report
Title:A retrospective study of acute pancreatitis in patients with hemorrhagic
fever with renal syndrome
Version: 3Date:1 October 2013
Reviewer: Rakesh Kochhar
Reviewer's report:
Major comments: The authors have explained that other etiologies of acute
pancreatitis were excluded. And they argue that presence of pain and imaging
findings despite normal enzymes are good enough to diagnose acute
pancreatitis. One could debate that; though. the authors should discuss this fact
(normal enzymes) in their discussion.
They also need to suggest the possible pathogenesis of acute pancreatitis in the
viral hemorrhagic fever. And discuss why should occurrence of pancreatitis in
their patients be linked to Hanta virus.
The conclusion of " In addition, when HFRS patients present with abdominal
pain, pancreatic enzyme levels should be detected and imaging analyses should
be conducted to assess the function and morphology of the pancreas to detect
the complications of AP " needs to be modified becauase one cannot say that all
patients of abdominal pain(65%) with Hanta virus infection should have a CT
scan. And they should also discuss the implications of diagnosing AP in the
hemorrhagic fever patients.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Reviewer's report
Title:A retrospective study of acute pancreatitis in patients with hemorrhagic
fever with renal syndrome
Version: 3Date:1 October 2013
Reviewer: Rakesh Kochhar
Reviewer's report:
Major comments: The authors have explained that other etiologies of acute
pancreatitis were excluded. And they argue that presence of pain and imaging
findings despite normal enzymes are good enough to diagnose acute
pancreatitis. One could debate that; though. the authors should discuss this fact
(normal enzymes) in their discussion.
They also need to suggest the possible pathogenesis of acute pancreatitis in the
viral hemorrhagic fever. And discuss why should occurrence of pancreatitis in
their patients be linked to Hanta virus.
The conclusion of " In addition, when HFRS patients present with abdominal
pain, pancreatic enzyme levels should be detected and imaging analyses should
be conducted to assess the function and morphology of the pancreas to detect
the complications of AP " needs to be modified becauase one cannot say that all
patients of abdominal pain(65%) with Hanta virus infection should have a CT
scan. And they should also discuss the implications of diagnosing AP in the
hemorrhagic fever patients.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Please review this paper.
user
Reviewer's report
Title:A retrospective study of acute pancreatitis in patients with hemorrhagic
fever with renal syndrome
Version: 3Date:1 October 2013
Reviewer: Rakesh Kochhar
Reviewer's report:
Major comments: The authors have explained that other etiologies of acute
pancreatitis were excluded. And they argue that presence of pain and imaging
findings despite normal enzymes are good enough to diagnose acute
pancreatitis. One could debate that; though. the authors should discuss this fact
(normal enzymes) in their discussion.
They also need to suggest the possible pathogenesis of acute pancreatitis in the
viral hemorrhagic fever. And discuss why should occurrence of pancreatitis in
their patients be linked to Hanta virus.
The conclusion of " In addition, when HFRS patients present with abdominal
pain, pancreatic enzyme levels should be detected and imaging analyses should
be conducted to assess the function and morphology of the pancreas to detect
the complications of AP " needs to be modified becauase one cannot say that all
patients of abdominal pain(65%) with Hanta virus infection should have a CT
scan. And they should also discuss the implications of diagnosing AP in the
hemorrhagic fever patients.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a
statistician.
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