Title: The insoluble excretion of multi-matrix system mesalazine preparations in patients with
ulcerative colitis
Version: 3 Date: 26 May 2022
Reviewer's report:
Did the authors investigate the taking of H2 blocker or proton pump inhibitor? These drugs are
thought to affect the rate of insoluble exercise.
Clinical and endoscopic severity is also critical to be affected insoluble exercise.
Is there any evidence whether insoluble exercise is associated to clinical outcome?
Title: The insoluble excretion of multi-matrix system mesalazine preparations in patients with
ulcerative colitis
Version: 3 Date: 26 May 2022
Reviewer's report:
Did the authors investigate the taking of H2 blocker or proton pump inhibitor? These drugs are
thought to affect the rate of insoluble exercise.
Clinical and endoscopic severity is also critical to be affected insoluble exercise.
Is there any evidence whether insoluble exercise is associated to clinical outcome?
Please review this paper.
user
Title: The insoluble excretion of multi-matrix system mesalazine preparations in patients with
ulcerative colitis
Version: 3 Date: 26 May 2022
Reviewer's report:
Did the authors investigate the taking of H2 blocker or proton pump inhibitor? These drugs are
thought to affect the rate of insoluble exercise.
Clinical and endoscopic severity is also critical to be affected insoluble exercise.
Is there any evidence whether insoluble exercise is associated to clinical outcome?
assistant