Reviewer's report
Title:Increasing abdominal pressure with and without PEEP: Effects on
intra-peritoneal, intra-organ and intra-vascular pressures
Version: 3Date:21 February 2010
Reviewer: Alexander Schachtrupp
Reviewer's report:
Discretionary Revisions:
The authors have clearly improved the manuscript by a detailed answer to
reviewers comments as well as by a detailed inclusion of the available literature.
It would certainly be desirable to have information about the influence of several
PEEP levels on a IAP relevant also for the diagnosis of ACS.
The publication of this data however, may be very useful for future studies as
background and hypothesis generation.
Minor comments:
All pressure transducers were simultaneously zeroed to a level corresponding to
the ventral border of the front leg.
As position of the animal may vary in comparison to other porcine studies the
usage of a small figure or a sketch is recommended.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests
Reviewer's report
Title:Increasing abdominal pressure with and without PEEP: Effects on
intra-peritoneal, intra-organ and intra-vascular pressures
Version: 3Date:21 February 2010
Reviewer: Alexander Schachtrupp
Reviewer's report:
Discretionary Revisions:
The authors have clearly improved the manuscript by a detailed answer to
reviewers comments as well as by a detailed inclusion of the available literature.
It would certainly be desirable to have information about the influence of several
PEEP levels on a IAP relevant also for the diagnosis of ACS.
The publication of this data however, may be very useful for future studies as
background and hypothesis generation.
Minor comments:
All pressure transducers were simultaneously zeroed to a level corresponding to
the ventral border of the front leg.
As position of the animal may vary in comparison to other porcine studies the
usage of a small figure or a sketch is recommended.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests
Please review this paper.
user
Reviewer's report
Title:Increasing abdominal pressure with and without PEEP: Effects on
intra-peritoneal, intra-organ and intra-vascular pressures
Version: 3Date:21 February 2010
Reviewer: Alexander Schachtrupp
Reviewer's report:
Discretionary Revisions:
The authors have clearly improved the manuscript by a detailed answer to
reviewers comments as well as by a detailed inclusion of the available literature.
It would certainly be desirable to have information about the influence of several
PEEP levels on a IAP relevant also for the diagnosis of ACS.
The publication of this data however, may be very useful for future studies as
background and hypothesis generation.
Minor comments:
All pressure transducers were simultaneously zeroed to a level corresponding to
the ventral border of the front leg.
As position of the animal may vary in comparison to other porcine studies the
usage of a small figure or a sketch is recommended.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests
assistant