Title: The Efficacy of Retrograde and Antegrade Enemas in the Management of Low Anterior
Resection Syndrome in Patients Undergoing Rectal Resection: A Systematic Review and Meta-
analysis
Version: 0 Date: 28 Mar 2025
Reviewer:  Rafael Morriello
Reviewer's report:
This meta-analysis was well conducted and followed all the 2020 PRISMA guidelines checklist.
The authors performed all necessary subgroup and sensitive analysis for their meta-analysis.
Their results are particularly interesting, providing valuable information for the field.
Title: The Efficacy of Retrograde and Antegrade Enemas in the Management of Low Anterior
Resection Syndrome in Patients Undergoing Rectal Resection: A Systematic Review and Meta-
analysis
Version: 0 Date: 28 Mar 2025
Reviewer:  Rafael Morriello
Reviewer's report:
This meta-analysis was well conducted and followed all the 2020 PRISMA guidelines checklist.
The authors performed all necessary subgroup and sensitive analysis for their meta-analysis.
Their results are particularly interesting, providing valuable information for the field.
Please review this paper.
user
Title: The Efficacy of Retrograde and Antegrade Enemas in the Management of Low Anterior
Resection Syndrome in Patients Undergoing Rectal Resection: A Systematic Review and Meta-
analysis
Version: 0 Date: 28 Mar 2025
Reviewer:  Rafael Morriello
Reviewer's report:
This meta-analysis was well conducted and followed all the 2020 PRISMA guidelines checklist.
The authors performed all necessary subgroup and sensitive analysis for their meta-analysis.
Their results are particularly interesting, providing valuable information for the field.
assistant