Title: Characteristics, clinical outcomes and patient-reported outcomes of patients with
ulcerative colitis receiving tofacitinib: a real-world survey in the United States and five European
countries
Version: 1 Date: 13 Nov 2022
Reviewer's report:
This article examines the therapeutic effect of tofacitinib for each administration period. This
is very useful to know the real-world therapeutic effect of tofacitinib. It is also interesting to
note that both physicians and patients were asked about the effectiveness of tofacitinib and their
satisfaction with the treatment. When such surveys are conducted, they often target a small
number of medical institutions or only one country. However, this survey was conducted on a
large number of physicians and patients in multiple countries, and the results indicate a high
level of treatment efficacy and satisfaction with tofacitinib, which is considered more credible. I
believe that this is very useful for physicians and patients who are considering using tofacitinib
in the future.
The following points should be reconsidered.
1. While tofacitinib is expected to have a high therapeutic effect, various side effects have been
reported. Does this article investigate the appearance of side effects? Also, does the appearance
of side effects affect the satisfaction of physicians and patients with the treatment?
2. I believe that satisfaction with treatment is also influenced by medical costs. Has the level of
satisfaction with medical costs been surveyed?
Title: Characteristics, clinical outcomes and patient-reported outcomes of patients with
ulcerative colitis receiving tofacitinib: a real-world survey in the United States and five European
countries
Version: 1 Date: 13 Nov 2022
Reviewer's report:
This article examines the therapeutic effect of tofacitinib for each administration period. This
is very useful to know the real-world therapeutic effect of tofacitinib. It is also interesting to
note that both physicians and patients were asked about the effectiveness of tofacitinib and their
satisfaction with the treatment. When such surveys are conducted, they often target a small
number of medical institutions or only one country. However, this survey was conducted on a
large number of physicians and patients in multiple countries, and the results indicate a high
level of treatment efficacy and satisfaction with tofacitinib, which is considered more credible. I
believe that this is very useful for physicians and patients who are considering using tofacitinib
in the future.
The following points should be reconsidered.
1. While tofacitinib is expected to have a high therapeutic effect, various side effects have been
reported. Does this article investigate the appearance of side effects? Also, does the appearance
of side effects affect the satisfaction of physicians and patients with the treatment?
2. I believe that satisfaction with treatment is also influenced by medical costs. Has the level of
satisfaction with medical costs been surveyed?
Please review this paper.
user
Title: Characteristics, clinical outcomes and patient-reported outcomes of patients with
ulcerative colitis receiving tofacitinib: a real-world survey in the United States and five European
countries
Version: 1 Date: 13 Nov 2022
Reviewer's report:
This article examines the therapeutic effect of tofacitinib for each administration period. This
is very useful to know the real-world therapeutic effect of tofacitinib. It is also interesting to
note that both physicians and patients were asked about the effectiveness of tofacitinib and their
satisfaction with the treatment. When such surveys are conducted, they often target a small
number of medical institutions or only one country. However, this survey was conducted on a
large number of physicians and patients in multiple countries, and the results indicate a high
level of treatment efficacy and satisfaction with tofacitinib, which is considered more credible. I
believe that this is very useful for physicians and patients who are considering using tofacitinib
in the future.
The following points should be reconsidered.
1. While tofacitinib is expected to have a high therapeutic effect, various side effects have been
reported. Does this article investigate the appearance of side effects? Also, does the appearance
of side effects affect the satisfaction of physicians and patients with the treatment?
2. I believe that satisfaction with treatment is also influenced by medical costs. Has the level of
satisfaction with medical costs been surveyed?
assistant