Title: Effectiveness of Endoscopic Papillectomy with Stent Placement in Pancreatic and Bile
Ducts for Treating Duodenal Papillary Adenoma: A Retrospective Study
Version: 1 Date: 29 Jul 2024
Reviewer's report:
I read with great interest the article titled “Effectiveness of Endoscopic Papillectomy with
Stent Placement in Pancreatic and Bile Ducts for Treating Duodenal Papillary Adenoma: A
Retrospective Study” by Jiani et al.
This retrospective study describes the role of pancreatic and biliary stenting in management of
duodenal papillary adenomas. I have the following comments to be made for this study:
1. Abstract: please mention primary and secondary outcomes of the study in methods section.
Moreover, also mention percentages (values) in results section, wherever it can be done.
2. Section of “endoscopic procedures”:
a. specify and give reference of which guideline that was followed for anti-coagulation/anti-
platelet stoppage
b. Please provide the detailed technique of performing endoscopic papillectomy in a
supplementary table: discussing various nuances practiced at author’s center and devices used
for the same.
c. What was the “indication” as to which case will receive biliary or pancreatic stenting or both
or no stent at all ? please specify in the methodology. The guidelines clearly suggest to place
PD stent (ASGE) to prevent PEP rates.
d. Please specify whether adverse events were recorded as per ASGE lexicon and AGREE
classification ? if not, please do the same and mention in the manuscript.
e. What criteria was followed for assessing which cases will need stent removal ?
f. Please mention what all was done on follow-up ? as per manuscript, all cases underwent biopsy
of the resected area ?
3. Definitions: please specify the references of articles which authors have used for their
definitions.
4. Put the follow up part in methodology and remove from section of definitions.
5. Results: section of population characteristics: As per Figure 1, the cases of non-pancreatic
stenting includes cases with biliary stenting also; similarly the case is true vice cersa for non-
biliary stented cases which includes pancreatic stenting. Ideally, if the authors have made 4
groups, the comparison of each should be made with those cases which have no-stent (both
biliary and pancreatic) to show whether a single or combination of stents has any role to play in
adverse events and post-resection outcomes on recurrence of adenoma.
6. please modify the results and discussion of the manuscript accordingly as per suggestions
given above.
Title: Effectiveness of Endoscopic Papillectomy with Stent Placement in Pancreatic and Bile
Ducts for Treating Duodenal Papillary Adenoma: A Retrospective Study
Version: 1 Date: 29 Jul 2024
Reviewer's report:
I read with great interest the article titled “Effectiveness of Endoscopic Papillectomy with
Stent Placement in Pancreatic and Bile Ducts for Treating Duodenal Papillary Adenoma: A
Retrospective Study” by Jiani et al.
This retrospective study describes the role of pancreatic and biliary stenting in management of
duodenal papillary adenomas. I have the following comments to be made for this study:
1. Abstract: please mention primary and secondary outcomes of the study in methods section.
Moreover, also mention percentages (values) in results section, wherever it can be done.
2. Section of “endoscopic procedures”:
a. specify and give reference of which guideline that was followed for anti-coagulation/anti-
platelet stoppage
b. Please provide the detailed technique of performing endoscopic papillectomy in a
supplementary table: discussing various nuances practiced at author’s center and devices used
for the same.
c. What was the “indication” as to which case will receive biliary or pancreatic stenting or both
or no stent at all ? please specify in the methodology. The guidelines clearly suggest to place
PD stent (ASGE) to prevent PEP rates.
d. Please specify whether adverse events were recorded as per ASGE lexicon and AGREE
classification ? if not, please do the same and mention in the manuscript.
e. What criteria was followed for assessing which cases will need stent removal ?
f. Please mention what all was done on follow-up ? as per manuscript, all cases underwent biopsy
of the resected area ?
3. Definitions: please specify the references of articles which authors have used for their
definitions.
4. Put the follow up part in methodology and remove from section of definitions.
5. Results: section of population characteristics: As per Figure 1, the cases of non-pancreatic
stenting includes cases with biliary stenting also; similarly the case is true vice cersa for non-
biliary stented cases which includes pancreatic stenting. Ideally, if the authors have made 4
groups, the comparison of each should be made with those cases which have no-stent (both
biliary and pancreatic) to show whether a single or combination of stents has any role to play in
adverse events and post-resection outcomes on recurrence of adenoma.
6. please modify the results and discussion of the manuscript accordingly as per suggestions
given above.
Please review this paper.
user
Title: Effectiveness of Endoscopic Papillectomy with Stent Placement in Pancreatic and Bile
Ducts for Treating Duodenal Papillary Adenoma: A Retrospective Study
Version: 1 Date: 29 Jul 2024
Reviewer's report:
I read with great interest the article titled “Effectiveness of Endoscopic Papillectomy with
Stent Placement in Pancreatic and Bile Ducts for Treating Duodenal Papillary Adenoma: A
Retrospective Study” by Jiani et al.
This retrospective study describes the role of pancreatic and biliary stenting in management of
duodenal papillary adenomas. I have the following comments to be made for this study:
1. Abstract: please mention primary and secondary outcomes of the study in methods section.
Moreover, also mention percentages (values) in results section, wherever it can be done.
2. Section of “endoscopic procedures”:
a. specify and give reference of which guideline that was followed for anti-coagulation/anti-
platelet stoppage
b. Please provide the detailed technique of performing endoscopic papillectomy in a
supplementary table: discussing various nuances practiced at author’s center and devices used
for the same.
c. What was the “indication” as to which case will receive biliary or pancreatic stenting or both
or no stent at all ? please specify in the methodology. The guidelines clearly suggest to place
PD stent (ASGE) to prevent PEP rates.
d. Please specify whether adverse events were recorded as per ASGE lexicon and AGREE
classification ? if not, please do the same and mention in the manuscript.
e. What criteria was followed for assessing which cases will need stent removal ?
f. Please mention what all was done on follow-up ? as per manuscript, all cases underwent biopsy
of the resected area ?
3. Definitions: please specify the references of articles which authors have used for their
definitions.
4. Put the follow up part in methodology and remove from section of definitions.
5. Results: section of population characteristics: As per Figure 1, the cases of non-pancreatic
stenting includes cases with biliary stenting also; similarly the case is true vice cersa for non-
biliary stented cases which includes pancreatic stenting. Ideally, if the authors have made 4
groups, the comparison of each should be made with those cases which have no-stent (both
biliary and pancreatic) to show whether a single or combination of stents has any role to play in
adverse events and post-resection outcomes on recurrence of adenoma.
6. please modify the results and discussion of the manuscript accordingly as per suggestions
given above.
assistant