Reviewer's report
Title:Co-culture of primary human tumor hepatocytes from patients with
hepatocellular carcinoma with autologous peripheral blood mononuclear cells:
Study of their in vitro immunological interactions.
Version: 2Date:8 October 2012
Reviewer: Svenja Sydor
Reviewer's report:
As a minor comment I recommended to depict standard deviation in their graphs.
Although the authors rsponded to my comment by providing standard deviations
the revised changes are not acceptable yet. In figures 4c and 5c graph scales
are not correct thus standard deviations are not illustrated completely or seem to
be truncated.
I recommend changing the graph's scales to show standard deviations as a
whole. Furthermore SD levels are very high so significant changes between
some groups appear remarkable but due to a collective of 11 patients/cell
preparations it may be possible.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests.
Reviewer's report
Title:Co-culture of primary human tumor hepatocytes from patients with
hepatocellular carcinoma with autologous peripheral blood mononuclear cells:
Study of their in vitro immunological interactions.
Version: 2Date:8 October 2012
Reviewer: Svenja Sydor
Reviewer's report:
As a minor comment I recommended to depict standard deviation in their graphs.
Although the authors rsponded to my comment by providing standard deviations
the revised changes are not acceptable yet. In figures 4c and 5c graph scales
are not correct thus standard deviations are not illustrated completely or seem to
be truncated.
I recommend changing the graph's scales to show standard deviations as a
whole. Furthermore SD levels are very high so significant changes between
some groups appear remarkable but due to a collective of 11 patients/cell
preparations it may be possible.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests.
Please review this paper.
user
Reviewer's report
Title:Co-culture of primary human tumor hepatocytes from patients with
hepatocellular carcinoma with autologous peripheral blood mononuclear cells:
Study of their in vitro immunological interactions.
Version: 2Date:8 October 2012
Reviewer: Svenja Sydor
Reviewer's report:
As a minor comment I recommended to depict standard deviation in their graphs.
Although the authors rsponded to my comment by providing standard deviations
the revised changes are not acceptable yet. In figures 4c and 5c graph scales
are not correct thus standard deviations are not illustrated completely or seem to
be truncated.
I recommend changing the graph's scales to show standard deviations as a
whole. Furthermore SD levels are very high so significant changes between
some groups appear remarkable but due to a collective of 11 patients/cell
preparations it may be possible.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests.
assistant