Reviewer's report
Title:Visceral Obesity and the Risk of Barrett's Esophagus in Japanese Patients
with Non-alcoholic Fatty Liver Disease
Version: 1Date:5 May 2009
Reviewer: Elfriede Bollschweiler
Reviewer's report:
Akiyama and colleagues described in a retrospective study the correlation of BMI
and visceral obesity with the existence of Barrett Mucosa. They measured the
visceral obesity with the help of CT. I think that this paper is of great interst by
several points:
1. Barrett esophagus is an actual topic because of the risk for adenocarcinoma of
the esophagus.
2. In Japan the incidence of AC of the esophgus as well as gastroesophgeal
reflux is rare.
3. In this study the authors analysed patients with fatty liver disease.
This is a group with a higher prevalence of visceral obesity. And they found a
high rate of Barrett mucosa in this group.
4. The method for measuring visceral obesity is adequate.
The manuscript is well written, the statistical methods are adequate.
In my opinion the paper should be published in the present form.
Reviewer's report
Title:Visceral Obesity and the Risk of Barrett's Esophagus in Japanese Patients
with Non-alcoholic Fatty Liver Disease
Version: 1Date:5 May 2009
Reviewer: Elfriede Bollschweiler
Reviewer's report:
Akiyama and colleagues described in a retrospective study the correlation of BMI
and visceral obesity with the existence of Barrett Mucosa. They measured the
visceral obesity with the help of CT. I think that this paper is of great interst by
several points:
1. Barrett esophagus is an actual topic because of the risk for adenocarcinoma of
the esophagus.
2. In Japan the incidence of AC of the esophgus as well as gastroesophgeal
reflux is rare.
3. In this study the authors analysed patients with fatty liver disease.
This is a group with a higher prevalence of visceral obesity. And they found a
high rate of Barrett mucosa in this group.
4. The method for measuring visceral obesity is adequate.
The manuscript is well written, the statistical methods are adequate.
In my opinion the paper should be published in the present form.
Please review this paper.
user
Reviewer's report
Title:Visceral Obesity and the Risk of Barrett's Esophagus in Japanese Patients
with Non-alcoholic Fatty Liver Disease
Version: 1Date:5 May 2009
Reviewer: Elfriede Bollschweiler
Reviewer's report:
Akiyama and colleagues described in a retrospective study the correlation of BMI
and visceral obesity with the existence of Barrett Mucosa. They measured the
visceral obesity with the help of CT. I think that this paper is of great interst by
several points:
1. Barrett esophagus is an actual topic because of the risk for adenocarcinoma of
the esophagus.
2. In Japan the incidence of AC of the esophgus as well as gastroesophgeal
reflux is rare.
3. In this study the authors analysed patients with fatty liver disease.
This is a group with a higher prevalence of visceral obesity. And they found a
high rate of Barrett mucosa in this group.
4. The method for measuring visceral obesity is adequate.
The manuscript is well written, the statistical methods are adequate.
In my opinion the paper should be published in the present form.
assistant