Title: Impact of Nutrition Risk Index, Prognostic Nutritional Index and Skeletal Muscle Index
on early myelosuppression of first-line chemotherapy in stage IV gastric cancer patients
Version: 2 Date: 08 Aug 2024
Reviewer's report:
The paper provides very interesting data but it still needs a considerable revision
In this study, regimens of chemotherapy are not standardized. This study evaluated a mix of cases
treated with monotherapy (S-1/capecitabine) and doublet therapy (SOX/XELOX). Therefore, it
is unclear whether the myelosuppression is due to chemotherapy or nutritional status.
Furthermore, number of metastatic sits or presence of bone metastasis may affect the nutritional
status.
Authors should reanalyze after identifying these confounding factors.
Title: Impact of Nutrition Risk Index, Prognostic Nutritional Index and Skeletal Muscle Index
on early myelosuppression of first-line chemotherapy in stage IV gastric cancer patients
Version: 2 Date: 08 Aug 2024
Reviewer's report:
The paper provides very interesting data but it still needs a considerable revision
In this study, regimens of chemotherapy are not standardized. This study evaluated a mix of cases
treated with monotherapy (S-1/capecitabine) and doublet therapy (SOX/XELOX). Therefore, it
is unclear whether the myelosuppression is due to chemotherapy or nutritional status.
Furthermore, number of metastatic sits or presence of bone metastasis may affect the nutritional
status.
Authors should reanalyze after identifying these confounding factors.
Please review this paper.
user
Title: Impact of Nutrition Risk Index, Prognostic Nutritional Index and Skeletal Muscle Index
on early myelosuppression of first-line chemotherapy in stage IV gastric cancer patients
Version: 2 Date: 08 Aug 2024
Reviewer's report:
The paper provides very interesting data but it still needs a considerable revision
In this study, regimens of chemotherapy are not standardized. This study evaluated a mix of cases
treated with monotherapy (S-1/capecitabine) and doublet therapy (SOX/XELOX). Therefore, it
is unclear whether the myelosuppression is due to chemotherapy or nutritional status.
Furthermore, number of metastatic sits or presence of bone metastasis may affect the nutritional
status.
Authors should reanalyze after identifying these confounding factors.
assistant