Reviewer's report
Title:Influence of Ketotifen, Cromolyn Sodium, and Compound 48/80 on the
survival rates after intestinal ischemia reperfusion injury in rats
Version: 3Date:16 June 2008
Reviewer: Igor Sukhotnik
Reviewer's report:
1-The answers were satisfactory. The authors note that they have financial
problens to detect the intestinal parameters. However, the measurement of
bowel and mucosal weight, mucosal DNA and protein as well as villus height or
crypt depth does not require a big financial support.
2-This reference is not appropriate. It concerns to changes in intestine during
hemorrhagis shock. Although blod flow in SMA is decreased during hemorrhagic
shock, the mechanisms of intestinal injury in shock is different from IR.
Level of interest: An article of limited interest
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Reviewer's report
Title:Influence of Ketotifen, Cromolyn Sodium, and Compound 48/80 on the
survival rates after intestinal ischemia reperfusion injury in rats
Version: 3Date:16 June 2008
Reviewer: Igor Sukhotnik
Reviewer's report:
1-The answers were satisfactory. The authors note that they have financial
problens to detect the intestinal parameters. However, the measurement of
bowel and mucosal weight, mucosal DNA and protein as well as villus height or
crypt depth does not require a big financial support.
2-This reference is not appropriate. It concerns to changes in intestine during
hemorrhagis shock. Although blod flow in SMA is decreased during hemorrhagic
shock, the mechanisms of intestinal injury in shock is different from IR.
Level of interest: An article of limited interest
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Please review this paper.
user
Reviewer's report
Title:Influence of Ketotifen, Cromolyn Sodium, and Compound 48/80 on the
survival rates after intestinal ischemia reperfusion injury in rats
Version: 3Date:16 June 2008
Reviewer: Igor Sukhotnik
Reviewer's report:
1-The answers were satisfactory. The authors note that they have financial
problens to detect the intestinal parameters. However, the measurement of
bowel and mucosal weight, mucosal DNA and protein as well as villus height or
crypt depth does not require a big financial support.
2-This reference is not appropriate. It concerns to changes in intestine during
hemorrhagis shock. Although blod flow in SMA is decreased during hemorrhagic
shock, the mechanisms of intestinal injury in shock is different from IR.
Level of interest: An article of limited interest
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
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