Title: Timing of endoscopy in patients with acute variceal bleeding in cirrhosis: An updated
systematic review and meta-analysis
Version: 0 Date: 11 May 2025
Reviewer's report:
While the authors provide a comprehensive and well-conducted meta-analysis on the timing of
endoscopy in acute variceal bleeding (AVB), the interpretation of their findings—particularly
the increased mortality associated with endoscopy within 6 hours—warrants critical caution due
to potential confounding by indication.
Title: Timing of endoscopy in patients with acute variceal bleeding in cirrhosis: An updated
systematic review and meta-analysis
Version: 0 Date: 11 May 2025
Reviewer's report:
While the authors provide a comprehensive and well-conducted meta-analysis on the timing of
endoscopy in acute variceal bleeding (AVB), the interpretation of their findings—particularly
the increased mortality associated with endoscopy within 6 hours—warrants critical caution due
to potential confounding by indication.
Please review this paper.
user
Title: Timing of endoscopy in patients with acute variceal bleeding in cirrhosis: An updated
systematic review and meta-analysis
Version: 0 Date: 11 May 2025
Reviewer's report:
While the authors provide a comprehensive and well-conducted meta-analysis on the timing of
endoscopy in acute variceal bleeding (AVB), the interpretation of their findings—particularly
the increased mortality associated with endoscopy within 6 hours—warrants critical caution due
to potential confounding by indication.
assistant