Title: Feasibility of Cholecystectomy in Patients with Silent Common Bile Duct Stones Cohort
prospective single arm multicentre study
Version: 3 Date: 17 Jul 2024
Reviewer:  Ahmed Elgeidie
Reviewer's report:
I think the research idea is not valid.
There is a general agreement in surgical society that CBD stones once detected must be removed,
simply because of feared consequences.
Another point is the clinical presentation. I mean that presenting epigastric pain may be due
to gallbladder stones but also may be due to CBD stones, even in the presence of a normal
biochemical tests . Therefore, it may be difficult to discern the actual cause.
Finally, we all know that the gallbladder is a good reservoir for bile, so when we remove it the
CBD stone will mostly be symptomatic. In such case, even if the CBD stone presence is silent,
LC will make it not silent.
For these reasons I found the principle research idea unfathomable.
Title: Feasibility of Cholecystectomy in Patients with Silent Common Bile Duct Stones Cohort
prospective single arm multicentre study
Version: 3 Date: 17 Jul 2024
Reviewer:  Ahmed Elgeidie
Reviewer's report:
I think the research idea is not valid.
There is a general agreement in surgical society that CBD stones once detected must be removed,
simply because of feared consequences.
Another point is the clinical presentation. I mean that presenting epigastric pain may be due
to gallbladder stones but also may be due to CBD stones, even in the presence of a normal
biochemical tests . Therefore, it may be difficult to discern the actual cause.
Finally, we all know that the gallbladder is a good reservoir for bile, so when we remove it the
CBD stone will mostly be symptomatic. In such case, even if the CBD stone presence is silent,
LC will make it not silent.
For these reasons I found the principle research idea unfathomable.
Please review this paper.
user
Title: Feasibility of Cholecystectomy in Patients with Silent Common Bile Duct Stones Cohort
prospective single arm multicentre study
Version: 3 Date: 17 Jul 2024
Reviewer:  Ahmed Elgeidie
Reviewer's report:
I think the research idea is not valid.
There is a general agreement in surgical society that CBD stones once detected must be removed,
simply because of feared consequences.
Another point is the clinical presentation. I mean that presenting epigastric pain may be due
to gallbladder stones but also may be due to CBD stones, even in the presence of a normal
biochemical tests . Therefore, it may be difficult to discern the actual cause.
Finally, we all know that the gallbladder is a good reservoir for bile, so when we remove it the
CBD stone will mostly be symptomatic. In such case, even if the CBD stone presence is silent,
LC will make it not silent.
For these reasons I found the principle research idea unfathomable.
assistant