Title: Clinical Characteristics and Treatment Outcomes of Primary Malignant Melanoma of
Esophagus: A Single Center Experience
Version: 3 Date: 02 Mar 2022
Reviewer's report:
“Clinical Characteristics and Treatment Outcomes of Primary Malignant Melanoma of
Esophagus: A Single Center Experience” retrospectively reviewed 17 patients diagnosed with
PMME. This manuscript has a depth analysis for PMME and interesting discovery ,but dure to
limited case number, the conclusions need to be very carefully.
As#surgery did not significantly improve overall survival while patients with diffusely
infiltrative tumor morphology(only two cases) showed better overall survival.
And please also mention the sample size and statistical differences during the discussion.
Title: Clinical Characteristics and Treatment Outcomes of Primary Malignant Melanoma of
Esophagus: A Single Center Experience
Version: 3 Date: 02 Mar 2022
Reviewer's report:
“Clinical Characteristics and Treatment Outcomes of Primary Malignant Melanoma of
Esophagus: A Single Center Experience” retrospectively reviewed 17 patients diagnosed with
PMME. This manuscript has a depth analysis for PMME and interesting discovery ,but dure to
limited case number, the conclusions need to be very carefully.
As#surgery did not significantly improve overall survival while patients with diffusely
infiltrative tumor morphology(only two cases) showed better overall survival.
And please also mention the sample size and statistical differences during the discussion.
Please review this paper.
user
Title: Clinical Characteristics and Treatment Outcomes of Primary Malignant Melanoma of
Esophagus: A Single Center Experience
Version: 3 Date: 02 Mar 2022
Reviewer's report:
“Clinical Characteristics and Treatment Outcomes of Primary Malignant Melanoma of
Esophagus: A Single Center Experience” retrospectively reviewed 17 patients diagnosed with
PMME. This manuscript has a depth analysis for PMME and interesting discovery ,but dure to
limited case number, the conclusions need to be very carefully.
As#surgery did not significantly improve overall survival while patients with diffusely
infiltrative tumor morphology(only two cases) showed better overall survival.
And please also mention the sample size and statistical differences during the discussion.
assistant