Title: Predictive factors for esophageal stenosis in patients receiving prophylactic steroid
therapy after endoscopic submucosal dissection for esophageal squamous cell carcinoma
Version: 1 Date: 31 Oct 2023
Reviewer's report:
I appreciate the opportunity for peer review on this article. The authors analyzed predictors of
esophageal stenosis in patients receiving prophylactic steroids after ESD and concluded that
total circumferential resection and a history of CRT were risk factors. However, in order to
accept the article, we would like to make the following comments.
Major
1. Although this is a retrospective study, as the authors mentioned in the limitation section, we
believe that different treatment strategies for steroid administration will have different effects
on stenosis. This may affect the number of EBD and thus the reliability of the data obtained in
this study. We believe that it is better to select cases for analysis in which the treatment strategy
(i.e., oral and local injection steroid use) was the same.
2. The fact that circumferential resection is a risk factor for causing refractory stenosis has been
reported in several studies and is not a new finding. We would like to know the reasons why
some patients have been successfully treated with circumferential resection without stenosis.
Minor
1. The method is described in the results section and the description method should be organized.
Title: Predictive factors for esophageal stenosis in patients receiving prophylactic steroid
therapy after endoscopic submucosal dissection for esophageal squamous cell carcinoma
Version: 1 Date: 31 Oct 2023
Reviewer's report:
I appreciate the opportunity for peer review on this article. The authors analyzed predictors of
esophageal stenosis in patients receiving prophylactic steroids after ESD and concluded that
total circumferential resection and a history of CRT were risk factors. However, in order to
accept the article, we would like to make the following comments.
Major
1. Although this is a retrospective study, as the authors mentioned in the limitation section, we
believe that different treatment strategies for steroid administration will have different effects
on stenosis. This may affect the number of EBD and thus the reliability of the data obtained in
this study. We believe that it is better to select cases for analysis in which the treatment strategy
(i.e., oral and local injection steroid use) was the same.
2. The fact that circumferential resection is a risk factor for causing refractory stenosis has been
reported in several studies and is not a new finding. We would like to know the reasons why
some patients have been successfully treated with circumferential resection without stenosis.
Minor
1. The method is described in the results section and the description method should be organized.
Please review this paper.
user
Title: Predictive factors for esophageal stenosis in patients receiving prophylactic steroid
therapy after endoscopic submucosal dissection for esophageal squamous cell carcinoma
Version: 1 Date: 31 Oct 2023
Reviewer's report:
I appreciate the opportunity for peer review on this article. The authors analyzed predictors of
esophageal stenosis in patients receiving prophylactic steroids after ESD and concluded that
total circumferential resection and a history of CRT were risk factors. However, in order to
accept the article, we would like to make the following comments.
Major
1. Although this is a retrospective study, as the authors mentioned in the limitation section, we
believe that different treatment strategies for steroid administration will have different effects
on stenosis. This may affect the number of EBD and thus the reliability of the data obtained in
this study. We believe that it is better to select cases for analysis in which the treatment strategy
(i.e., oral and local injection steroid use) was the same.
2. The fact that circumferential resection is a risk factor for causing refractory stenosis has been
reported in several studies and is not a new finding. We would like to know the reasons why
some patients have been successfully treated with circumferential resection without stenosis.
Minor
1. The method is described in the results section and the description method should be organized.
assistant