Title: Atrophic gastritis rather than Helicobacter pylori infection can be an independent risk
factor of colorectal polyps: a retrospective study in China
Version: 6 Date: 04 Apr 2023
Reviewer's report:
The title of the article fully corresponds to the content and main conclusion. In the “Introduction”
section, the authors skillfully explain the feasibility of the study, demonstrating a good
knowledge of previous studies.
Methods of work correspond to the purpose of the study, allow to achieve objective results. The
authors examined 792 patients. Colorectal polyps were found in 385 people, atrophic gastritis
- in 332 patients. Multivariate analysis showed that age, gender, and atrophic gastritis were
independent risk factors for colorectal polyps. AUC for association of atrophic gastritis and
colorectal polyps was 0.62 (p<0.001), for Helicobacter pylori infection it was 0.57 (p<0.001).
The Discussion section is written in good, clear language. The authors interpret the results
obtained in the light of previous studies and skillfully substantiate the novelty of the work and
the possible pathogenetic relationship between atrophic gastritis and colorectal polyps. The list
of references includes 31 works that are modern and allow substantiating the significance and
novelty of the study. There are no comments on the quality of diagrams and drawings. Ethical
requirements in accordance with the Declaration of Helsinki were observed in the work.
The work was performed using modern research methods on a large clinical material, which
made it possible to obtain original data on the direct relationship between atrophic gastritis and
colorectal polyps, which are of great practical and theoretical significance. The materials of the
article are presented in a good clear language.
The authors made adjustments to the article in accordance with the comments made. The article
may be published in the journal BMC Gastroenterology.
Title: Atrophic gastritis rather than Helicobacter pylori infection can be an independent risk
factor of colorectal polyps: a retrospective study in China
Version: 6 Date: 04 Apr 2023
Reviewer's report:
The title of the article fully corresponds to the content and main conclusion. In the “Introduction”
section, the authors skillfully explain the feasibility of the study, demonstrating a good
knowledge of previous studies.
Methods of work correspond to the purpose of the study, allow to achieve objective results. The
authors examined 792 patients. Colorectal polyps were found in 385 people, atrophic gastritis
- in 332 patients. Multivariate analysis showed that age, gender, and atrophic gastritis were
independent risk factors for colorectal polyps. AUC for association of atrophic gastritis and
colorectal polyps was 0.62 (p<0.001), for Helicobacter pylori infection it was 0.57 (p<0.001).
The Discussion section is written in good, clear language. The authors interpret the results
obtained in the light of previous studies and skillfully substantiate the novelty of the work and
the possible pathogenetic relationship between atrophic gastritis and colorectal polyps. The list
of references includes 31 works that are modern and allow substantiating the significance and
novelty of the study. There are no comments on the quality of diagrams and drawings. Ethical
requirements in accordance with the Declaration of Helsinki were observed in the work.
The work was performed using modern research methods on a large clinical material, which
made it possible to obtain original data on the direct relationship between atrophic gastritis and
colorectal polyps, which are of great practical and theoretical significance. The materials of the
article are presented in a good clear language.
The authors made adjustments to the article in accordance with the comments made. The article
may be published in the journal BMC Gastroenterology.
Please review this paper.
user
Title: Atrophic gastritis rather than Helicobacter pylori infection can be an independent risk
factor of colorectal polyps: a retrospective study in China
Version: 6 Date: 04 Apr 2023
Reviewer's report:
The title of the article fully corresponds to the content and main conclusion. In the “Introduction”
section, the authors skillfully explain the feasibility of the study, demonstrating a good
knowledge of previous studies.
Methods of work correspond to the purpose of the study, allow to achieve objective results. The
authors examined 792 patients. Colorectal polyps were found in 385 people, atrophic gastritis
- in 332 patients. Multivariate analysis showed that age, gender, and atrophic gastritis were
independent risk factors for colorectal polyps. AUC for association of atrophic gastritis and
colorectal polyps was 0.62 (p<0.001), for Helicobacter pylori infection it was 0.57 (p<0.001).
The Discussion section is written in good, clear language. The authors interpret the results
obtained in the light of previous studies and skillfully substantiate the novelty of the work and
the possible pathogenetic relationship between atrophic gastritis and colorectal polyps. The list
of references includes 31 works that are modern and allow substantiating the significance and
novelty of the study. There are no comments on the quality of diagrams and drawings. Ethical
requirements in accordance with the Declaration of Helsinki were observed in the work.
The work was performed using modern research methods on a large clinical material, which
made it possible to obtain original data on the direct relationship between atrophic gastritis and
colorectal polyps, which are of great practical and theoretical significance. The materials of the
article are presented in a good clear language.
The authors made adjustments to the article in accordance with the comments made. The article
may be published in the journal BMC Gastroenterology.
assistant