Title: Establishment of a prognostic signature based on fatty acid metabolism genes in HCC
associated with hepatitis B
Version: 2 Date: 13 Jun 2023
Reviewer's report:
1. Power Analysis of the sample size should be done. Power analysis descriptions and the power
value of the study should be given in the Data Collection section.
2. In the statistical analysis section; It should be added that Kaplan-Meier survival analysis,
LASSO-penalized Cox regression analysis, time-dependent receiver operating characteristic
(ROC) curve analysis, nomogram analysis and correlation analysis are used. It should also be
written that R software is used.
3. Test Set is the set where validation is done. The training and test set sample rates should be
specified (such as 60%-40% or 70%-30%).
4. Statistical results are given with figures, not tables. However, the readability level of numerical
values on the figures is low. Figures should be given more clearly and statistical significance
(p-values) should be added.
Title: Establishment of a prognostic signature based on fatty acid metabolism genes in HCC
associated with hepatitis B
Version: 2 Date: 13 Jun 2023
Reviewer's report:
1. Power Analysis of the sample size should be done. Power analysis descriptions and the power
value of the study should be given in the Data Collection section.
2. In the statistical analysis section; It should be added that Kaplan-Meier survival analysis,
LASSO-penalized Cox regression analysis, time-dependent receiver operating characteristic
(ROC) curve analysis, nomogram analysis and correlation analysis are used. It should also be
written that R software is used.
3. Test Set is the set where validation is done. The training and test set sample rates should be
specified (such as 60%-40% or 70%-30%).
4. Statistical results are given with figures, not tables. However, the readability level of numerical
values on the figures is low. Figures should be given more clearly and statistical significance
(p-values) should be added.
Please review this paper.
user
Title: Establishment of a prognostic signature based on fatty acid metabolism genes in HCC
associated with hepatitis B
Version: 2 Date: 13 Jun 2023
Reviewer's report:
1. Power Analysis of the sample size should be done. Power analysis descriptions and the power
value of the study should be given in the Data Collection section.
2. In the statistical analysis section; It should be added that Kaplan-Meier survival analysis,
LASSO-penalized Cox regression analysis, time-dependent receiver operating characteristic
(ROC) curve analysis, nomogram analysis and correlation analysis are used. It should also be
written that R software is used.
3. Test Set is the set where validation is done. The training and test set sample rates should be
specified (such as 60%-40% or 70%-30%).
4. Statistical results are given with figures, not tables. However, the readability level of numerical
values on the figures is low. Figures should be given more clearly and statistical significance
(p-values) should be added.
assistant