Reviewer's report 
 Lifestyle as a predictor for colonic neoplasia in asymptomatic individuals Title: 
 3  25 July 2005 Version: Date: 
 Ole Kronborg Reviewer: 
Reviewer's report: 
General 
Ac---------------------------------------------------------------------------- 
Major Compulsory Revisions (that the author must respond to before a decision on publication can 
be reached) 
The data in Fig 1 are already mentioned in the text. The data in tables 2-3are very exhorbitant and it 
might be easier for the reader to avoid illustrating some of the non-significant findings 
Discussion: The very limited age groups included may to some degree compromize the wider 
application of the results and this aspectmust be discussed. Furthermore the reasons for the definitions of advanced neoplasia should be given and the number of actual cancers stated. Finally 
it would be interesting to know how the authors valuate the importance of adherence to the lifestyle 
recommendations mentioned. The authors should be appraised for having used the opportunity to perform a nested case-control study. 
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Minor Essential Revisions (such as missing labels on figures, or the wrong use of a term, which the 
author can be trusted to correct) 
------------------------------------------------------------------------------- 
Discretionary Revisions (which the author can choose to ignore) 
 Accept after minor essential revisions What next?: 
 An article of importance in its field Level of interest: 
 Acceptable Quality of written English: 
 No Statistical review: 
Declaration of competing interests: 
I declare that I have no competing interests 
Reviewer's report 
 Lifestyle as a predictor for colonic neoplasia in asymptomatic individuals Title: 
 3  25 July 2005 Version: Date: 
 Ole Kronborg Reviewer: 
Reviewer's report: 
General 
Ac---------------------------------------------------------------------------- 
Major Compulsory Revisions (that the author must respond to before a decision on publication can 
be reached) 
The data in Fig 1 are already mentioned in the text. The data in tables 2-3are very exhorbitant and it 
might be easier for the reader to avoid illustrating some of the non-significant findings 
Discussion: The very limited age groups included may to some degree compromize the wider 
application of the results and this aspectmust be discussed. Furthermore the reasons for the definitions of advanced neoplasia should be given and the number of actual cancers stated. Finally 
it would be interesting to know how the authors valuate the importance of adherence to the lifestyle 
recommendations mentioned. The authors should be appraised for having used the opportunity to perform a nested case-control study. 
------------------------------------------------------------------------------- 
Minor Essential Revisions (such as missing labels on figures, or the wrong use of a term, which the 
author can be trusted to correct) 
------------------------------------------------------------------------------- 
Discretionary Revisions (which the author can choose to ignore) 
 Accept after minor essential revisions What next?: 
 An article of importance in its field Level of interest: 
 Acceptable Quality of written English: 
 No Statistical review: 
Declaration of competing interests: 
I declare that I have no competing interests 
Please review this paper.
user
Reviewer's report 
 Lifestyle as a predictor for colonic neoplasia in asymptomatic individuals Title: 
 3  25 July 2005 Version: Date: 
 Ole Kronborg Reviewer: 
Reviewer's report: 
General 
Ac---------------------------------------------------------------------------- 
Major Compulsory Revisions (that the author must respond to before a decision on publication can 
be reached) 
The data in Fig 1 are already mentioned in the text. The data in tables 2-3are very exhorbitant and it 
might be easier for the reader to avoid illustrating some of the non-significant findings 
Discussion: The very limited age groups included may to some degree compromize the wider 
application of the results and this aspectmust be discussed. Furthermore the reasons for the definitions of advanced neoplasia should be given and the number of actual cancers stated. Finally 
it would be interesting to know how the authors valuate the importance of adherence to the lifestyle 
recommendations mentioned. The authors should be appraised for having used the opportunity to perform a nested case-control study. 
------------------------------------------------------------------------------- 
Minor Essential Revisions (such as missing labels on figures, or the wrong use of a term, which the 
author can be trusted to correct) 
------------------------------------------------------------------------------- 
Discretionary Revisions (which the author can choose to ignore) 
 Accept after minor essential revisions What next?: 
 An article of importance in its field Level of interest: 
 Acceptable Quality of written English: 
 No Statistical review: 
Declaration of competing interests: 
I declare that I have no competing interests 
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