Title: Can transrectal ultrasonography distinguish anorectal malignant melanoma from low
rectal adenocarcinoma? a retrospective paired study for ten years
Version: 1 Date: 23 Nov 2021
Reviewer's report:
thank you for the opportunity to review this retrospective study comparing the characteristics
of primary rectal melanoma and adenocarcinoma. Can transrectal ultrasonography distinguish
anorectal malignant melanoma from low rectal adenocarcinoma? a retrospective paired study
for ten years. this study included 36 patients from 2008 to 2019. why tumor matching was only
performed on the sex and age of the patients. it is difficult to conclude that primary melanomas
are more superficial than adenocarcinomas of the lower rectum when all the tumors have not
been included. in fact, in the case of superficial adenocarcinomas of the rectum that are accessible
to local treatment, the majority of endorectal echo-endoscopies find only a limited invasion of
the wall.  It would have been more judicious to describe the complete series and to report the
anatomopathological results compared with those of the echo-endoscopic work-up. Moreover,
magnetic resonance imaging still has a complementary place in preoperative explorations.
Title: Can transrectal ultrasonography distinguish anorectal malignant melanoma from low
rectal adenocarcinoma? a retrospective paired study for ten years
Version: 1 Date: 23 Nov 2021
Reviewer's report:
thank you for the opportunity to review this retrospective study comparing the characteristics
of primary rectal melanoma and adenocarcinoma. Can transrectal ultrasonography distinguish
anorectal malignant melanoma from low rectal adenocarcinoma? a retrospective paired study
for ten years. this study included 36 patients from 2008 to 2019. why tumor matching was only
performed on the sex and age of the patients. it is difficult to conclude that primary melanomas
are more superficial than adenocarcinomas of the lower rectum when all the tumors have not
been included. in fact, in the case of superficial adenocarcinomas of the rectum that are accessible
to local treatment, the majority of endorectal echo-endoscopies find only a limited invasion of
the wall.  It would have been more judicious to describe the complete series and to report the
anatomopathological results compared with those of the echo-endoscopic work-up. Moreover,
magnetic resonance imaging still has a complementary place in preoperative explorations.
Please review this paper.
user
Title: Can transrectal ultrasonography distinguish anorectal malignant melanoma from low
rectal adenocarcinoma? a retrospective paired study for ten years
Version: 1 Date: 23 Nov 2021
Reviewer's report:
thank you for the opportunity to review this retrospective study comparing the characteristics
of primary rectal melanoma and adenocarcinoma. Can transrectal ultrasonography distinguish
anorectal malignant melanoma from low rectal adenocarcinoma? a retrospective paired study
for ten years. this study included 36 patients from 2008 to 2019. why tumor matching was only
performed on the sex and age of the patients. it is difficult to conclude that primary melanomas
are more superficial than adenocarcinomas of the lower rectum when all the tumors have not
been included. in fact, in the case of superficial adenocarcinomas of the rectum that are accessible
to local treatment, the majority of endorectal echo-endoscopies find only a limited invasion of
the wall.  It would have been more judicious to describe the complete series and to report the
anatomopathological results compared with those of the echo-endoscopic work-up. Moreover,
magnetic resonance imaging still has a complementary place in preoperative explorations.
assistant