Reviewer's report
Title:Antibodies against gonadotropin-releasing hormone (GnRH) and
destruction of enteric neurons in 3 patients suffering from gastrointestinal
dysfunction
Version: 2Date:23 February 2010
Reviewer: Philippe Ducrotte
Reviewer's report:
General comment
This is an interesting study raising an original hypothesis to explain some severe
GI motility disorders. Even if the mechanistic study in animals is not absolutely
convincing, it provides some additional interesting informations. The paper is well
written.
Minor comment
Is figure 2 useful ?
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests.
Reviewer's report
Title:Antibodies against gonadotropin-releasing hormone (GnRH) and
destruction of enteric neurons in 3 patients suffering from gastrointestinal
dysfunction
Version: 2Date:23 February 2010
Reviewer: Philippe Ducrotte
Reviewer's report:
General comment
This is an interesting study raising an original hypothesis to explain some severe
GI motility disorders. Even if the mechanistic study in animals is not absolutely
convincing, it provides some additional interesting informations. The paper is well
written.
Minor comment
Is figure 2 useful ?
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests.
Please review this paper.
user
Reviewer's report
Title:Antibodies against gonadotropin-releasing hormone (GnRH) and
destruction of enteric neurons in 3 patients suffering from gastrointestinal
dysfunction
Version: 2Date:23 February 2010
Reviewer: Philippe Ducrotte
Reviewer's report:
General comment
This is an interesting study raising an original hypothesis to explain some severe
GI motility disorders. Even if the mechanistic study in animals is not absolutely
convincing, it provides some additional interesting informations. The paper is well
written.
Minor comment
Is figure 2 useful ?
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests.
assistant