Reviewer's report
Title:Excretion of urinary histamine and N-tele methylhistamine in
gastrointestinal food allergy
Version:2Date:29 October 2014
Reviewer: Ivy Shiue
Reviewer's report:
This study seems to attempt to study the relationship of urinary histamine and
N-tele methylhistamine and food allergy.
1) Title: Please be more specific. The current working title is only very general.
2) Abstract: There was no study aimed stated and no study design mentioned. Is
it a case control study? A clinical trial? A case report?
3) Introduction: It's well-written.
4) Methods: Study design is unclear. Please explain in details. How are csaes
and controls identified and categorised? Any matching criteria? Study sample
selection is unclear. Please describe clearly in details. A diagram might be
helpful. Patient characteristics should be reported in Results but not in Methods.
No ethics approval seemed to be reported clearly.
5) Results: There should be a table describing and comparing individual
characteristics between "cases" and "controls". Did the authors consider other
statistical modeling such as regression models?
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: Yes, and I have assessed the statistics in my report.
Declaration of competing interests:
None
Reviewer's report
Title:Excretion of urinary histamine and N-tele methylhistamine in
gastrointestinal food allergy
Version:2Date:29 October 2014
Reviewer: Ivy Shiue
Reviewer's report:
This study seems to attempt to study the relationship of urinary histamine and
N-tele methylhistamine and food allergy.
1) Title: Please be more specific. The current working title is only very general.
2) Abstract: There was no study aimed stated and no study design mentioned. Is
it a case control study? A clinical trial? A case report?
3) Introduction: It's well-written.
4) Methods: Study design is unclear. Please explain in details. How are csaes
and controls identified and categorised? Any matching criteria? Study sample
selection is unclear. Please describe clearly in details. A diagram might be
helpful. Patient characteristics should be reported in Results but not in Methods.
No ethics approval seemed to be reported clearly.
5) Results: There should be a table describing and comparing individual
characteristics between "cases" and "controls". Did the authors consider other
statistical modeling such as regression models?
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: Yes, and I have assessed the statistics in my report.
Declaration of competing interests:
None
Please review this paper.
user
Reviewer's report
Title:Excretion of urinary histamine and N-tele methylhistamine in
gastrointestinal food allergy
Version:2Date:29 October 2014
Reviewer: Ivy Shiue
Reviewer's report:
This study seems to attempt to study the relationship of urinary histamine and
N-tele methylhistamine and food allergy.
1) Title: Please be more specific. The current working title is only very general.
2) Abstract: There was no study aimed stated and no study design mentioned. Is
it a case control study? A clinical trial? A case report?
3) Introduction: It's well-written.
4) Methods: Study design is unclear. Please explain in details. How are csaes
and controls identified and categorised? Any matching criteria? Study sample
selection is unclear. Please describe clearly in details. A diagram might be
helpful. Patient characteristics should be reported in Results but not in Methods.
No ethics approval seemed to be reported clearly.
5) Results: There should be a table describing and comparing individual
characteristics between "cases" and "controls". Did the authors consider other
statistical modeling such as regression models?
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: Yes, and I have assessed the statistics in my report.
Declaration of competing interests:
None
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