Title: Molecular Analyses of ADAMTS-1, -4, -5, and IL-17A Cytokine Relationship in Patients
with Ulcerative Colitis
Version: 2 Date: 10 Apr 2023
Reviewer's report:
The research methods and results of the article can be self-consistent, but through the query
of ‘The human protein atlas’ (https://www.proteinatlas.org/), it is suggested that the protein
expression of ADAMTS1 and ADAMTS4 in human colon tissue is very low. The main
expression of ADAMTS5 in human colon tissue is in glandular cells, which is different from
the situation shown in Fig. 2. It is hoped that the authors could explain it in conjunction with
relevant literature.
Title: Molecular Analyses of ADAMTS-1, -4, -5, and IL-17A Cytokine Relationship in Patients
with Ulcerative Colitis
Version: 2 Date: 10 Apr 2023
Reviewer's report:
The research methods and results of the article can be self-consistent, but through the query
of ‘The human protein atlas’ (https://www.proteinatlas.org/), it is suggested that the protein
expression of ADAMTS1 and ADAMTS4 in human colon tissue is very low. The main
expression of ADAMTS5 in human colon tissue is in glandular cells, which is different from
the situation shown in Fig. 2. It is hoped that the authors could explain it in conjunction with
relevant literature.
Please review this paper.
user
Title: Molecular Analyses of ADAMTS-1, -4, -5, and IL-17A Cytokine Relationship in Patients
with Ulcerative Colitis
Version: 2 Date: 10 Apr 2023
Reviewer's report:
The research methods and results of the article can be self-consistent, but through the query
of ‘The human protein atlas’ (https://www.proteinatlas.org/), it is suggested that the protein
expression of ADAMTS1 and ADAMTS4 in human colon tissue is very low. The main
expression of ADAMTS5 in human colon tissue is in glandular cells, which is different from
the situation shown in Fig. 2. It is hoped that the authors could explain it in conjunction with
relevant literature.
assistant