Title: Treatment and outcome of hepatorenal syndrome in Japan: A retrospective cohort study
using a national inpatient database
Version: 3 Date: 18 Jun 2023
Reviewer's report:
In this manuscript, Okushin et al. reported the nationwide study of the clinical characteristics,
treatment details, and mortality of Hepatorenal syndrome (HRS) by using The Japanese
Diagnosis Procedure Combination database. The authors concluded that HRS in Japan has a
high mortality rate. Although noradrenaline is recommended in Japanese clinical guidelines,
dopamine was more frequently used as a vasoconstrictor in clinical practice.
I think the revised paper is a very interesting and useful contribution.
Title: Treatment and outcome of hepatorenal syndrome in Japan: A retrospective cohort study
using a national inpatient database
Version: 3 Date: 18 Jun 2023
Reviewer's report:
In this manuscript, Okushin et al. reported the nationwide study of the clinical characteristics,
treatment details, and mortality of Hepatorenal syndrome (HRS) by using The Japanese
Diagnosis Procedure Combination database. The authors concluded that HRS in Japan has a
high mortality rate. Although noradrenaline is recommended in Japanese clinical guidelines,
dopamine was more frequently used as a vasoconstrictor in clinical practice.
I think the revised paper is a very interesting and useful contribution.
Please review this paper.
user
Title: Treatment and outcome of hepatorenal syndrome in Japan: A retrospective cohort study
using a national inpatient database
Version: 3 Date: 18 Jun 2023
Reviewer's report:
In this manuscript, Okushin et al. reported the nationwide study of the clinical characteristics,
treatment details, and mortality of Hepatorenal syndrome (HRS) by using The Japanese
Diagnosis Procedure Combination database. The authors concluded that HRS in Japan has a
high mortality rate. Although noradrenaline is recommended in Japanese clinical guidelines,
dopamine was more frequently used as a vasoconstrictor in clinical practice.
I think the revised paper is a very interesting and useful contribution.
assistant