Reviewer's report
Title:Hepatitis C virus core antigen, an earlier and stronger predictor on
sustained virological response in patients with genotype 1 HCV infection
Version:1Date:20 January 2014
Reviewer: Munechika Enjoji
Reviewer's report:
Earlier kinetics of HCVcAg and its predictive value of SVR were investigated in
this study, and #HCVcAg at 144 h was an earlier and stronger predictor than
RVR. This study includes novel findings which may be helpful for clinical
investigation of chronic hepatitis C. Then, this report has enough potential for
publication, I think.
Comments
1. [Abstract] Medical treatment regimen and duration should be presented
concretely.
2. [Table 4] Why 1 log was selected as a cutoff line of #HCVcAg?
3. Please check spelling and grammatical errors. For example; peglated
(Introduction; page 6, line 16).
Level of interest: An article of importance in its field
Quality of written English: Needs some language corrections before being
published
Statistical review: Yes, but I do not feel adequately qualified to assess the
statistics.
Declaration of competing interests:
I declare that I have no competing interests
Reviewer's report
Title:Hepatitis C virus core antigen, an earlier and stronger predictor on
sustained virological response in patients with genotype 1 HCV infection
Version:1Date:20 January 2014
Reviewer: Munechika Enjoji
Reviewer's report:
Earlier kinetics of HCVcAg and its predictive value of SVR were investigated in
this study, and #HCVcAg at 144 h was an earlier and stronger predictor than
RVR. This study includes novel findings which may be helpful for clinical
investigation of chronic hepatitis C. Then, this report has enough potential for
publication, I think.
Comments
1. [Abstract] Medical treatment regimen and duration should be presented
concretely.
2. [Table 4] Why 1 log was selected as a cutoff line of #HCVcAg?
3. Please check spelling and grammatical errors. For example; peglated
(Introduction; page 6, line 16).
Level of interest: An article of importance in its field
Quality of written English: Needs some language corrections before being
published
Statistical review: Yes, but I do not feel adequately qualified to assess the
statistics.
Declaration of competing interests:
I declare that I have no competing interests
Please review this paper.
user
Reviewer's report
Title:Hepatitis C virus core antigen, an earlier and stronger predictor on
sustained virological response in patients with genotype 1 HCV infection
Version:1Date:20 January 2014
Reviewer: Munechika Enjoji
Reviewer's report:
Earlier kinetics of HCVcAg and its predictive value of SVR were investigated in
this study, and #HCVcAg at 144 h was an earlier and stronger predictor than
RVR. This study includes novel findings which may be helpful for clinical
investigation of chronic hepatitis C. Then, this report has enough potential for
publication, I think.
Comments
1. [Abstract] Medical treatment regimen and duration should be presented
concretely.
2. [Table 4] Why 1 log was selected as a cutoff line of #HCVcAg?
3. Please check spelling and grammatical errors. For example; peglated
(Introduction; page 6, line 16).
Level of interest: An article of importance in its field
Quality of written English: Needs some language corrections before being
published
Statistical review: Yes, but I do not feel adequately qualified to assess the
statistics.
Declaration of competing interests:
I declare that I have no competing interests
assistant