Title: The 30-day hospital readmission and mortality after surgery in colorectal cancer patients
Version: 3 Date: 13 Jun 2022
Reviewer's report:
Authors reported that no prior studies assess the colorectal cancer rate  of hospital readimissions
among the Saudi population. The authors stated that Saudi peoples experienced CRC at late
stages with low survival rate and the rate of readmission after surgery is unknown. Following
datas from the Ministry of National Guard- Health Affairs Cancer Registry, the present study
aims to assess and clarify these issues. Identifying the rate of readmission and its predictors will
contribute to the development of interventions that should reduce readmission, hospitalization
costs and improve cancer patient outcomes
This is a retrospective cohort study that uses data from a Saudi national registry and it was
approved by King Abdullah international medical research center. Statistical analysis was well
conducted.
Compared to non-readmitted patients, readmitted patients were less likely to have regional stage
(55.10% vs. 63.52%; P-value=0.03) but more likely to have a distant metastasis (34.69 vs.
17.26; P-value=0.03). In the univariate analysis, there was a positive association between age
and readmission and females had higher odds of readmission than males, but both did not reach
a significance level.
The authors found that 13.76% of CRC patients were readmitted within 30-day of index
hospitalization, a finding that is slightly higher than previous studies. Gastrointestinal, urinary
tract and surgical site infection were the most frequent causes of readmission. Metastatic disease
is a reknowned factor that could affect the readmission rate.….
The high rate of open surgery (about 70%) can affect the high rate of readmissions for infections
(surgical site infection or gastrointestinal infection)? I think that optimizing and developing
a minimally invasive surgery program could be an effective resource of containing costs and
readmissions.
Title: The 30-day hospital readmission and mortality after surgery in colorectal cancer patients
Version: 3 Date: 13 Jun 2022
Reviewer's report:
Authors reported that no prior studies assess the colorectal cancer rate  of hospital readimissions
among the Saudi population. The authors stated that Saudi peoples experienced CRC at late
stages with low survival rate and the rate of readmission after surgery is unknown. Following
datas from the Ministry of National Guard- Health Affairs Cancer Registry, the present study
aims to assess and clarify these issues. Identifying the rate of readmission and its predictors will
contribute to the development of interventions that should reduce readmission, hospitalization
costs and improve cancer patient outcomes
This is a retrospective cohort study that uses data from a Saudi national registry and it was
approved by King Abdullah international medical research center. Statistical analysis was well
conducted.
Compared to non-readmitted patients, readmitted patients were less likely to have regional stage
(55.10% vs. 63.52%; P-value=0.03) but more likely to have a distant metastasis (34.69 vs.
17.26; P-value=0.03). In the univariate analysis, there was a positive association between age
and readmission and females had higher odds of readmission than males, but both did not reach
a significance level.
The authors found that 13.76% of CRC patients were readmitted within 30-day of index
hospitalization, a finding that is slightly higher than previous studies. Gastrointestinal, urinary
tract and surgical site infection were the most frequent causes of readmission. Metastatic disease
is a reknowned factor that could affect the readmission rate.….
The high rate of open surgery (about 70%) can affect the high rate of readmissions for infections
(surgical site infection or gastrointestinal infection)? I think that optimizing and developing
a minimally invasive surgery program could be an effective resource of containing costs and
readmissions.
Please review this paper.
user
Title: The 30-day hospital readmission and mortality after surgery in colorectal cancer patients
Version: 3 Date: 13 Jun 2022
Reviewer's report:
Authors reported that no prior studies assess the colorectal cancer rate  of hospital readimissions
among the Saudi population. The authors stated that Saudi peoples experienced CRC at late
stages with low survival rate and the rate of readmission after surgery is unknown. Following
datas from the Ministry of National Guard- Health Affairs Cancer Registry, the present study
aims to assess and clarify these issues. Identifying the rate of readmission and its predictors will
contribute to the development of interventions that should reduce readmission, hospitalization
costs and improve cancer patient outcomes
This is a retrospective cohort study that uses data from a Saudi national registry and it was
approved by King Abdullah international medical research center. Statistical analysis was well
conducted.
Compared to non-readmitted patients, readmitted patients were less likely to have regional stage
(55.10% vs. 63.52%; P-value=0.03) but more likely to have a distant metastasis (34.69 vs.
17.26; P-value=0.03). In the univariate analysis, there was a positive association between age
and readmission and females had higher odds of readmission than males, but both did not reach
a significance level.
The authors found that 13.76% of CRC patients were readmitted within 30-day of index
hospitalization, a finding that is slightly higher than previous studies. Gastrointestinal, urinary
tract and surgical site infection were the most frequent causes of readmission. Metastatic disease
is a reknowned factor that could affect the readmission rate.….
The high rate of open surgery (about 70%) can affect the high rate of readmissions for infections
(surgical site infection or gastrointestinal infection)? I think that optimizing and developing
a minimally invasive surgery program could be an effective resource of containing costs and
readmissions.
assistant