Reviewer's report
Title:Dyspeptic Symptoms and Delayed Gastric Emptying of Solids in Patients
with Inactive Crohn's Disease.
Version: 2Date:14 September 2012
Reviewer: J Keller
Reviewer's report:
Comment 2: The authors’ response does not answer my question. The upper
limit of normal for t ½ given by Ghoos et al. (Gastroenterology 1993) is 118 min.
Why did the authors choose 200 min and how do they explain that 3 out of 14
healthy subjects have delayed gastric emptying even when considering values
up to 200 min as normal? According to a previous analysis in more than 1000
patients age has no influence on t 1/2 when using the Ghoos method (Keller et
al. Neurogastroenterol Motil 2009).
Comment 5: From the data given in the manuscript I still doubt that there can be
a significant association between PADYQ score for vomiting and gastric
emptying velocity. It would be helpful to see the correlation.
Level of interest: An article of importance in its field
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
'I declare that I have no competing interests'
Reviewer's report
Title:Dyspeptic Symptoms and Delayed Gastric Emptying of Solids in Patients
with Inactive Crohn's Disease.
Version: 2Date:14 September 2012
Reviewer: J Keller
Reviewer's report:
Comment 2: The authors’ response does not answer my question. The upper
limit of normal for t ½ given by Ghoos et al. (Gastroenterology 1993) is 118 min.
Why did the authors choose 200 min and how do they explain that 3 out of 14
healthy subjects have delayed gastric emptying even when considering values
up to 200 min as normal? According to a previous analysis in more than 1000
patients age has no influence on t 1/2 when using the Ghoos method (Keller et
al. Neurogastroenterol Motil 2009).
Comment 5: From the data given in the manuscript I still doubt that there can be
a significant association between PADYQ score for vomiting and gastric
emptying velocity. It would be helpful to see the correlation.
Level of interest: An article of importance in its field
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
'I declare that I have no competing interests'
Please review this paper.
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Reviewer's report
Title:Dyspeptic Symptoms and Delayed Gastric Emptying of Solids in Patients
with Inactive Crohn's Disease.
Version: 2Date:14 September 2012
Reviewer: J Keller
Reviewer's report:
Comment 2: The authors’ response does not answer my question. The upper
limit of normal for t ½ given by Ghoos et al. (Gastroenterology 1993) is 118 min.
Why did the authors choose 200 min and how do they explain that 3 out of 14
healthy subjects have delayed gastric emptying even when considering values
up to 200 min as normal? According to a previous analysis in more than 1000
patients age has no influence on t 1/2 when using the Ghoos method (Keller et
al. Neurogastroenterol Motil 2009).
Comment 5: From the data given in the manuscript I still doubt that there can be
a significant association between PADYQ score for vomiting and gastric
emptying velocity. It would be helpful to see the correlation.
Level of interest: An article of importance in its field
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
'I declare that I have no competing interests'
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