Title: Association between wet-bulb globe temperature with peptic ulcer disease in different
geographic regions in a large Taiwanese population study
Version: 2 Date: 11 Feb 2025
Reviewer's report:
This study aimed to explore the association between wet-bulb globe temperature and peptic
ulcer disease among different geographical regions of Taiwan. Although this study is interesting,
several ambiguous points remain. Please see the comments below.
1. In abstract, the detailed method is unclear regarding which model was used to examine the
association. Moreover, reporting odds ratios (ORs) with their 95% confidence intervals seems
to be better than reporting the p-value.
2. In method section, a diagram illustrating the selection of final participants through inclusion
and exclusion criteria must be added.
3. In the section of “Definition of PUD”, the specific criteria that used to classify the participants
into PUD and non-PUD groups must be explained intensively.
4. In the result section, the combined number of men and women is not equal to the total number
of participants. Please check that again carefully.
5. In Table 3, what is the reason for the difference in the association between WBGT and PUD
at different time intervals in Northern Taiwan, where a negative association was found for the
noon period and a marginally positive association was observed for the working period? This
must be further discussed.
Title: Association between wet-bulb globe temperature with peptic ulcer disease in different
geographic regions in a large Taiwanese population study
Version: 2 Date: 11 Feb 2025
Reviewer's report:
This study aimed to explore the association between wet-bulb globe temperature and peptic
ulcer disease among different geographical regions of Taiwan. Although this study is interesting,
several ambiguous points remain. Please see the comments below.
1. In abstract, the detailed method is unclear regarding which model was used to examine the
association. Moreover, reporting odds ratios (ORs) with their 95% confidence intervals seems
to be better than reporting the p-value.
2. In method section, a diagram illustrating the selection of final participants through inclusion
and exclusion criteria must be added.
3. In the section of “Definition of PUD”, the specific criteria that used to classify the participants
into PUD and non-PUD groups must be explained intensively.
4. In the result section, the combined number of men and women is not equal to the total number
of participants. Please check that again carefully.
5. In Table 3, what is the reason for the difference in the association between WBGT and PUD
at different time intervals in Northern Taiwan, where a negative association was found for the
noon period and a marginally positive association was observed for the working period? This
must be further discussed.
Please review this paper.
user
Title: Association between wet-bulb globe temperature with peptic ulcer disease in different
geographic regions in a large Taiwanese population study
Version: 2 Date: 11 Feb 2025
Reviewer's report:
This study aimed to explore the association between wet-bulb globe temperature and peptic
ulcer disease among different geographical regions of Taiwan. Although this study is interesting,
several ambiguous points remain. Please see the comments below.
1. In abstract, the detailed method is unclear regarding which model was used to examine the
association. Moreover, reporting odds ratios (ORs) with their 95% confidence intervals seems
to be better than reporting the p-value.
2. In method section, a diagram illustrating the selection of final participants through inclusion
and exclusion criteria must be added.
3. In the section of “Definition of PUD”, the specific criteria that used to classify the participants
into PUD and non-PUD groups must be explained intensively.
4. In the result section, the combined number of men and women is not equal to the total number
of participants. Please check that again carefully.
5. In Table 3, what is the reason for the difference in the association between WBGT and PUD
at different time intervals in Northern Taiwan, where a negative association was found for the
noon period and a marginally positive association was observed for the working period? This
must be further discussed.
assistant