Reviewer's report
Title:Outcomes of endoscopic management of primary and refractory
postcholecystectomy biliary leaks in a multicentre review of 178 patients
Version:2Date:28 May 2015
Reviewer: SHUNJUN FU
Reviewer's report:
Reviewer’s report
Title: Outcomes of endoscopic management of primary and refractory
postcholecystectomy biliary leaks in a multicentre review of 178 patients
Version:1Date: 27 May 2015
Reviewer: Shun-Jun Fu
Reviewer's report:
The authors explored the clinical effectiveness of initial endotherapy for post-
cholecystectomy biliary leaks using an homogenous approach (sphincterotomy +
placement of a 10-French plastic stent) in a large series of patients as well as the
optimal and efficacy of rescue endotherapy for refractory biliary leaks. The study
is a very valuable research of clinical application. I have some questions for the
study.
Major Compulsory Revisions
1. How many patients was received laparoscopic cholecystectomy (LC) in your 4
institutions between March 2009 and July 2014? How much is the incidence of
biliary leaks? How much is the incidence of biliary injury? Many literary studies
and our experience showed that the incidence of biliary injury is higher than
biliary leak. Only biliary leak not biliary injury can be mostly solved by biliary
drainage in the percutaneous drains according to our experience. How to
explain?
2. How to deal with cystic duct stump when LC? Hamlock or Absorbable Clips?
Minor Essential Revisions
Line 260, page 12
“a median period of 67 days (range, 30-67 days)”. Is he median period of 67 days
same as the maximum 67 days?
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
I declare that I have no competing interests
Reviewer's report
Title:Outcomes of endoscopic management of primary and refractory
postcholecystectomy biliary leaks in a multicentre review of 178 patients
Version:2Date:28 May 2015
Reviewer: SHUNJUN FU
Reviewer's report:
Reviewer’s report
Title: Outcomes of endoscopic management of primary and refractory
postcholecystectomy biliary leaks in a multicentre review of 178 patients
Version:1Date: 27 May 2015
Reviewer: Shun-Jun Fu
Reviewer's report:
The authors explored the clinical effectiveness of initial endotherapy for post-
cholecystectomy biliary leaks using an homogenous approach (sphincterotomy +
placement of a 10-French plastic stent) in a large series of patients as well as the
optimal and efficacy of rescue endotherapy for refractory biliary leaks. The study
is a very valuable research of clinical application. I have some questions for the
study.
Major Compulsory Revisions
1. How many patients was received laparoscopic cholecystectomy (LC) in your 4
institutions between March 2009 and July 2014? How much is the incidence of
biliary leaks? How much is the incidence of biliary injury? Many literary studies
and our experience showed that the incidence of biliary injury is higher than
biliary leak. Only biliary leak not biliary injury can be mostly solved by biliary
drainage in the percutaneous drains according to our experience. How to
explain?
2. How to deal with cystic duct stump when LC? Hamlock or Absorbable Clips?
Minor Essential Revisions
Line 260, page 12
“a median period of 67 days (range, 30-67 days)”. Is he median period of 67 days
same as the maximum 67 days?
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
I declare that I have no competing interests
Please review this paper.
user
Reviewer's report
Title:Outcomes of endoscopic management of primary and refractory
postcholecystectomy biliary leaks in a multicentre review of 178 patients
Version:2Date:28 May 2015
Reviewer: SHUNJUN FU
Reviewer's report:
Reviewer’s report
Title: Outcomes of endoscopic management of primary and refractory
postcholecystectomy biliary leaks in a multicentre review of 178 patients
Version:1Date: 27 May 2015
Reviewer: Shun-Jun Fu
Reviewer's report:
The authors explored the clinical effectiveness of initial endotherapy for post-
cholecystectomy biliary leaks using an homogenous approach (sphincterotomy +
placement of a 10-French plastic stent) in a large series of patients as well as the
optimal and efficacy of rescue endotherapy for refractory biliary leaks. The study
is a very valuable research of clinical application. I have some questions for the
study.
Major Compulsory Revisions
1. How many patients was received laparoscopic cholecystectomy (LC) in your 4
institutions between March 2009 and July 2014? How much is the incidence of
biliary leaks? How much is the incidence of biliary injury? Many literary studies
and our experience showed that the incidence of biliary injury is higher than
biliary leak. Only biliary leak not biliary injury can be mostly solved by biliary
drainage in the percutaneous drains according to our experience. How to
explain?
2. How to deal with cystic duct stump when LC? Hamlock or Absorbable Clips?
Minor Essential Revisions
Line 260, page 12
“a median period of 67 days (range, 30-67 days)”. Is he median period of 67 days
same as the maximum 67 days?
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
I declare that I have no competing interests
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