Title: Intriguing findings of liver fibrosis following Covid-19
Version: 1 Date: 08 Jul 2021
Reviewer's report:
The authors investigated changes in liver fibrosis in COVID-19 patients, they assessed serum
hyaluronic acid and FIB-4   in 66 patients and 17 controls. They found that these markers may
be elevated  in more than half of patients in the study. I would like to thank the authors for this
great effort. However, l have major concerns:
- Sample size calculation and power of the study is important to validate the findings of the study.
- l also would like to ask why you selected 66 patients and 17 controls. Why this number and
not another number?
-In introduction, in the last sentence of the fourth paragraph, you stated that FIB-4 may not be
valid marker for fibrosis. SO, Why you selected FIB-4 for the study?
- In the third paragraph of methods, you mentioned that if the case has oxygen saturation below
93%, this will be considered respiratory failure. I ask you to revise this piece of information and
provide the reference for that.
Best regards
Title: Intriguing findings of liver fibrosis following Covid-19
Version: 1 Date: 08 Jul 2021
Reviewer's report:
The authors investigated changes in liver fibrosis in COVID-19 patients, they assessed serum
hyaluronic acid and FIB-4   in 66 patients and 17 controls. They found that these markers may
be elevated  in more than half of patients in the study. I would like to thank the authors for this
great effort. However, l have major concerns:
- Sample size calculation and power of the study is important to validate the findings of the study.
- l also would like to ask why you selected 66 patients and 17 controls. Why this number and
not another number?
-In introduction, in the last sentence of the fourth paragraph, you stated that FIB-4 may not be
valid marker for fibrosis. SO, Why you selected FIB-4 for the study?
- In the third paragraph of methods, you mentioned that if the case has oxygen saturation below
93%, this will be considered respiratory failure. I ask you to revise this piece of information and
provide the reference for that.
Best regards
Please review this paper.
user
Title: Intriguing findings of liver fibrosis following Covid-19
Version: 1 Date: 08 Jul 2021
Reviewer's report:
The authors investigated changes in liver fibrosis in COVID-19 patients, they assessed serum
hyaluronic acid and FIB-4   in 66 patients and 17 controls. They found that these markers may
be elevated  in more than half of patients in the study. I would like to thank the authors for this
great effort. However, l have major concerns:
- Sample size calculation and power of the study is important to validate the findings of the study.
- l also would like to ask why you selected 66 patients and 17 controls. Why this number and
not another number?
-In introduction, in the last sentence of the fourth paragraph, you stated that FIB-4 may not be
valid marker for fibrosis. SO, Why you selected FIB-4 for the study?
- In the third paragraph of methods, you mentioned that if the case has oxygen saturation below
93%, this will be considered respiratory failure. I ask you to revise this piece of information and
provide the reference for that.
Best regards
assistant