Title: Systemic immune-inflammation index within the first postoperative hour as a predictor of
severe postoperative complications in upper abdominal surgery: A retrospective single-center
study
Version: 1 Date: 11 Jul 2022
Reviewer's report:
Dear editor
Thank you for giving me the opportunity to evaluate this work.
In this study,  310 patients who underwent upper GIS surgery were evaluated, the success of the
SII in predicting postoperative complications was studied.
The study is generally well designed and well written. I have a few comments to the authors;
1- Those with active infection (total lymphocyte count > 10 9/l) who were included in the
exclusion criteria from the study should be more clearly stated.
2- Was the ethics committee approval for the study or was it only IRB approval? Was an author
from the surgical specialty included in this study?
3- Is it routine to get a hemogram and biochemistry at the postoperative 1st hour from patients
who have had all upper GIS operations in your hospital? For example, what would be the clinical
benefit of checking albumin routinely in the 1st postoperative hour?
4- As a practice in our center, patients at risk of delayed extubation after UAS would be
transferred to the anesthesia intensive care unit (AICU) for further observation
What are the criteria for "delayed extubation"? Is there information about the complication rates
in patients followed in the general surgery intensive care unit?
5- The exclusion criteria were patients with incomplete medical records, who underwent
complex surgical procedures, with severe anemia, active bleeding, neutropenia and/or active
infection (total lymphocyte count >109/L).
-----it is recommended that the authors do a flow-chart showing how many patients were
excluded from these criteria.
6- How the oxygenation index is calculated should be stated in the method section.
Title: Systemic immune-inflammation index within the first postoperative hour as a predictor of
severe postoperative complications in upper abdominal surgery: A retrospective single-center
study
Version: 1 Date: 11 Jul 2022
Reviewer's report:
Dear editor
Thank you for giving me the opportunity to evaluate this work.
In this study,  310 patients who underwent upper GIS surgery were evaluated, the success of the
SII in predicting postoperative complications was studied.
The study is generally well designed and well written. I have a few comments to the authors;
1- Those with active infection (total lymphocyte count > 10 9/l) who were included in the
exclusion criteria from the study should be more clearly stated.
2- Was the ethics committee approval for the study or was it only IRB approval? Was an author
from the surgical specialty included in this study?
3- Is it routine to get a hemogram and biochemistry at the postoperative 1st hour from patients
who have had all upper GIS operations in your hospital? For example, what would be the clinical
benefit of checking albumin routinely in the 1st postoperative hour?
4- As a practice in our center, patients at risk of delayed extubation after UAS would be
transferred to the anesthesia intensive care unit (AICU) for further observation
What are the criteria for "delayed extubation"? Is there information about the complication rates
in patients followed in the general surgery intensive care unit?
5- The exclusion criteria were patients with incomplete medical records, who underwent
complex surgical procedures, with severe anemia, active bleeding, neutropenia and/or active
infection (total lymphocyte count >109/L).
-----it is recommended that the authors do a flow-chart showing how many patients were
excluded from these criteria.
6- How the oxygenation index is calculated should be stated in the method section.
Please review this paper.
user
Title: Systemic immune-inflammation index within the first postoperative hour as a predictor of
severe postoperative complications in upper abdominal surgery: A retrospective single-center
study
Version: 1 Date: 11 Jul 2022
Reviewer's report:
Dear editor
Thank you for giving me the opportunity to evaluate this work.
In this study,  310 patients who underwent upper GIS surgery were evaluated, the success of the
SII in predicting postoperative complications was studied.
The study is generally well designed and well written. I have a few comments to the authors;
1- Those with active infection (total lymphocyte count > 10 9/l) who were included in the
exclusion criteria from the study should be more clearly stated.
2- Was the ethics committee approval for the study or was it only IRB approval? Was an author
from the surgical specialty included in this study?
3- Is it routine to get a hemogram and biochemistry at the postoperative 1st hour from patients
who have had all upper GIS operations in your hospital? For example, what would be the clinical
benefit of checking albumin routinely in the 1st postoperative hour?
4- As a practice in our center, patients at risk of delayed extubation after UAS would be
transferred to the anesthesia intensive care unit (AICU) for further observation
What are the criteria for "delayed extubation"? Is there information about the complication rates
in patients followed in the general surgery intensive care unit?
5- The exclusion criteria were patients with incomplete medical records, who underwent
complex surgical procedures, with severe anemia, active bleeding, neutropenia and/or active
infection (total lymphocyte count >109/L).
-----it is recommended that the authors do a flow-chart showing how many patients were
excluded from these criteria.
6- How the oxygenation index is calculated should be stated in the method section.
assistant