Reviewer's report
Title:Association between Helicobacter pylori cagA-related genes and clinical
outcomes in Colombia and Japan
Version: 2Date:15 August 2011
Reviewer: Hossein Dabiri
Reviewer's report:
- Major Compulsory Revisions
There is no need to major revision.
- Minor Essential Revisions
1- Page 6, line 6: each deoxynucleotide concentration must be written in
millimolar not Micro liter (µL)
2- Page 6, line 8: regarding the product size of used primers are short ( table 1),
thereby the PCR program as 30 cycles; 5 min at 94°C, 30 sec and 5 min at 72°C
seems uncommon and must be checked.
3-page 6 and 7: In some cases, the standard material sources addressing
(company, county) is not considered as the name of country is missed.
4- In case of table 2, since the references of selected genes have given in the
context, the table2 is no longer mandatory.
5- In case of the table 4 and 5, P value should be calculated for each row.
6- Page 9, paragraph2, in result section under subtitle of “The association
between candidate genes and clinical outcomes” only two genes (jhp0045,
jhp0046) of four studied genes (hp0967, jhp0045, jhp0046 and jhp0951) have
been considered.
7- Page 9, under subtitle of “The association between candidate genes and
clinical outcomes”: it is better to present each country result separately and more
clearly.
Level of interest: An article of outstanding merit and interest in its field
Quality of written English: Acceptable
Statistical review: Yes, but I do not feel adequately qualified to assess the
statistics.
Declaration of competing interests:
I declare that I have no competing interests.
Reviewer's report
Title:Association between Helicobacter pylori cagA-related genes and clinical
outcomes in Colombia and Japan
Version: 2Date:15 August 2011
Reviewer: Hossein Dabiri
Reviewer's report:
- Major Compulsory Revisions
There is no need to major revision.
- Minor Essential Revisions
1- Page 6, line 6: each deoxynucleotide concentration must be written in
millimolar not Micro liter (µL)
2- Page 6, line 8: regarding the product size of used primers are short ( table 1),
thereby the PCR program as 30 cycles; 5 min at 94°C, 30 sec and 5 min at 72°C
seems uncommon and must be checked.
3-page 6 and 7: In some cases, the standard material sources addressing
(company, county) is not considered as the name of country is missed.
4- In case of table 2, since the references of selected genes have given in the
context, the table2 is no longer mandatory.
5- In case of the table 4 and 5, P value should be calculated for each row.
6- Page 9, paragraph2, in result section under subtitle of “The association
between candidate genes and clinical outcomes” only two genes (jhp0045,
jhp0046) of four studied genes (hp0967, jhp0045, jhp0046 and jhp0951) have
been considered.
7- Page 9, under subtitle of “The association between candidate genes and
clinical outcomes”: it is better to present each country result separately and more
clearly.
Level of interest: An article of outstanding merit and interest in its field
Quality of written English: Acceptable
Statistical review: Yes, but I do not feel adequately qualified to assess the
statistics.
Declaration of competing interests:
I declare that I have no competing interests.
Please review this paper.
user
Reviewer's report
Title:Association between Helicobacter pylori cagA-related genes and clinical
outcomes in Colombia and Japan
Version: 2Date:15 August 2011
Reviewer: Hossein Dabiri
Reviewer's report:
- Major Compulsory Revisions
There is no need to major revision.
- Minor Essential Revisions
1- Page 6, line 6: each deoxynucleotide concentration must be written in
millimolar not Micro liter (µL)
2- Page 6, line 8: regarding the product size of used primers are short ( table 1),
thereby the PCR program as 30 cycles; 5 min at 94°C, 30 sec and 5 min at 72°C
seems uncommon and must be checked.
3-page 6 and 7: In some cases, the standard material sources addressing
(company, county) is not considered as the name of country is missed.
4- In case of table 2, since the references of selected genes have given in the
context, the table2 is no longer mandatory.
5- In case of the table 4 and 5, P value should be calculated for each row.
6- Page 9, paragraph2, in result section under subtitle of “The association
between candidate genes and clinical outcomes” only two genes (jhp0045,
jhp0046) of four studied genes (hp0967, jhp0045, jhp0046 and jhp0951) have
been considered.
7- Page 9, under subtitle of “The association between candidate genes and
clinical outcomes”: it is better to present each country result separately and more
clearly.
Level of interest: An article of outstanding merit and interest in its field
Quality of written English: Acceptable
Statistical review: Yes, but I do not feel adequately qualified to assess the
statistics.
Declaration of competing interests:
I declare that I have no competing interests.
assistant