Reviewer's report
Title:Combined use of AFP, CEA, CA125 and CAl9-9 improves the sensitivity
for the diagnosis of gastric cancer
Version: 2Date:9 February 2013
Reviewer: Qiang Tong
Reviewer's report:
Minor Essential Revisions
In this manuscript the authors aimed to determine whether the combined use of
AFP, CEA, CA125 and CAl9-9 tumor markers may increase the sensitivity for the
diagnosis of gastric cancer. The sample size of 149 patients with gastric cancer,
111 patients with benign gastric disease and 124 healthy people is reasonable
and reliable. The statistical analysis methods are appropriate. The results are
good and suggest that the optimal application of these common tumor markers
could improve the clinical screening and diagnosis of gastric cancer. Generally
speaking, this is a well-written manuscript and should be of interest to readers of
BMC Gastroenterology.
I only have some concern about the Tables. There are some incorrect
characters, please correct them.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: Yes, but I do not feel adequately qualified to assess the
statistics.
Declaration of competing interests:
I declare that I have no competing interests
Reviewer's report
Title:Combined use of AFP, CEA, CA125 and CAl9-9 improves the sensitivity
for the diagnosis of gastric cancer
Version: 2Date:9 February 2013
Reviewer: Qiang Tong
Reviewer's report:
Minor Essential Revisions
In this manuscript the authors aimed to determine whether the combined use of
AFP, CEA, CA125 and CAl9-9 tumor markers may increase the sensitivity for the
diagnosis of gastric cancer. The sample size of 149 patients with gastric cancer,
111 patients with benign gastric disease and 124 healthy people is reasonable
and reliable. The statistical analysis methods are appropriate. The results are
good and suggest that the optimal application of these common tumor markers
could improve the clinical screening and diagnosis of gastric cancer. Generally
speaking, this is a well-written manuscript and should be of interest to readers of
BMC Gastroenterology.
I only have some concern about the Tables. There are some incorrect
characters, please correct them.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: Yes, but I do not feel adequately qualified to assess the
statistics.
Declaration of competing interests:
I declare that I have no competing interests
Please review this paper.
user
Reviewer's report
Title:Combined use of AFP, CEA, CA125 and CAl9-9 improves the sensitivity
for the diagnosis of gastric cancer
Version: 2Date:9 February 2013
Reviewer: Qiang Tong
Reviewer's report:
Minor Essential Revisions
In this manuscript the authors aimed to determine whether the combined use of
AFP, CEA, CA125 and CAl9-9 tumor markers may increase the sensitivity for the
diagnosis of gastric cancer. The sample size of 149 patients with gastric cancer,
111 patients with benign gastric disease and 124 healthy people is reasonable
and reliable. The statistical analysis methods are appropriate. The results are
good and suggest that the optimal application of these common tumor markers
could improve the clinical screening and diagnosis of gastric cancer. Generally
speaking, this is a well-written manuscript and should be of interest to readers of
BMC Gastroenterology.
I only have some concern about the Tables. There are some incorrect
characters, please correct them.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: Yes, but I do not feel adequately qualified to assess the
statistics.
Declaration of competing interests:
I declare that I have no competing interests
assistant