Title: Efficiency of laparoscopic retroperitoneal pancreatic necrosectomy for treating infected
pancreatic necrosis with duodenal fistula: A single-center retrospective cohort study
Version: 2 Date: 30 Oct 2024
Reviewer:  Ioannis Maroulis
Reviewer's report:
I would like to congratulate the authors on their fascinating work regarding this interesting
report entitled “Efficiency of laparoscopic retroperitoneal pancreatic necrosectomy for treating
infected pancreatic necrosis with duodenal fistula: A single-center retrospective cohort study”.
The manuscript is well-written and the incorporated figures and tables make the study easy to
follow.
I strongly recommend acceptance for publication of the paper after minor revision:
1) I would suggest a brief discussion on new biomarkers on inflammatory postoperative
complications and the role of Butyrylcholinesterase (BChE) enzyme.
According to the literature, BChE has been proved a marker for the risk of developing SSI and
septic complications in patients undergoing colorectal surgery.
Add this information and consider citing the recently published article:
https://pubmed.ncbi.nlm.nih.gov/39229253/
Title: Efficiency of laparoscopic retroperitoneal pancreatic necrosectomy for treating infected
pancreatic necrosis with duodenal fistula: A single-center retrospective cohort study
Version: 2 Date: 30 Oct 2024
Reviewer:  Ioannis Maroulis
Reviewer's report:
I would like to congratulate the authors on their fascinating work regarding this interesting
report entitled “Efficiency of laparoscopic retroperitoneal pancreatic necrosectomy for treating
infected pancreatic necrosis with duodenal fistula: A single-center retrospective cohort study”.
The manuscript is well-written and the incorporated figures and tables make the study easy to
follow.
I strongly recommend acceptance for publication of the paper after minor revision:
1) I would suggest a brief discussion on new biomarkers on inflammatory postoperative
complications and the role of Butyrylcholinesterase (BChE) enzyme.
According to the literature, BChE has been proved a marker for the risk of developing SSI and
septic complications in patients undergoing colorectal surgery.
Add this information and consider citing the recently published article:
https://pubmed.ncbi.nlm.nih.gov/39229253/
Please review this paper.
user
Title: Efficiency of laparoscopic retroperitoneal pancreatic necrosectomy for treating infected
pancreatic necrosis with duodenal fistula: A single-center retrospective cohort study
Version: 2 Date: 30 Oct 2024
Reviewer:  Ioannis Maroulis
Reviewer's report:
I would like to congratulate the authors on their fascinating work regarding this interesting
report entitled “Efficiency of laparoscopic retroperitoneal pancreatic necrosectomy for treating
infected pancreatic necrosis with duodenal fistula: A single-center retrospective cohort study”.
The manuscript is well-written and the incorporated figures and tables make the study easy to
follow.
I strongly recommend acceptance for publication of the paper after minor revision:
1) I would suggest a brief discussion on new biomarkers on inflammatory postoperative
complications and the role of Butyrylcholinesterase (BChE) enzyme.
According to the literature, BChE has been proved a marker for the risk of developing SSI and
septic complications in patients undergoing colorectal surgery.
Add this information and consider citing the recently published article:
https://pubmed.ncbi.nlm.nih.gov/39229253/
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