Reviewer's report
Title:Role of serotonin in fatty acid-induced non-alcoholic fatty liver disease in
mice
Version: 4Date:19 August 2013
Reviewer: Bernhard Watzl
Reviewer's report:
The revised version has improved significantly and the authors have addressed
most of the reviewer's comments.
Some points still could be improved.
Lines 106 ff: Please indicate how many mice were used for the second
experiment.
Line 153: "...receiving a 6% fat diet". This is not in line with the information given
in Table 1 (11 %).
Lines 154-155: "...the means of the combined high-fat groups were calculated". I
do not think that this is correct because it ignores a potential impact of the fat
quality.
Line 168: "...fat quality had a pronounced effect" (see above).
Line 156ff: I still think that a two-way ANOVA would be correct. Is the outcome of
the analysis different between a one-way and a two-way ANOVA?
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: Yes, and I have assessed the statistics in my report.
Reviewer's report
Title:Role of serotonin in fatty acid-induced non-alcoholic fatty liver disease in
mice
Version: 4Date:19 August 2013
Reviewer: Bernhard Watzl
Reviewer's report:
The revised version has improved significantly and the authors have addressed
most of the reviewer's comments.
Some points still could be improved.
Lines 106 ff: Please indicate how many mice were used for the second
experiment.
Line 153: "...receiving a 6% fat diet". This is not in line with the information given
in Table 1 (11 %).
Lines 154-155: "...the means of the combined high-fat groups were calculated". I
do not think that this is correct because it ignores a potential impact of the fat
quality.
Line 168: "...fat quality had a pronounced effect" (see above).
Line 156ff: I still think that a two-way ANOVA would be correct. Is the outcome of
the analysis different between a one-way and a two-way ANOVA?
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: Yes, and I have assessed the statistics in my report.
Please review this paper.
user
Reviewer's report
Title:Role of serotonin in fatty acid-induced non-alcoholic fatty liver disease in
mice
Version: 4Date:19 August 2013
Reviewer: Bernhard Watzl
Reviewer's report:
The revised version has improved significantly and the authors have addressed
most of the reviewer's comments.
Some points still could be improved.
Lines 106 ff: Please indicate how many mice were used for the second
experiment.
Line 153: "...receiving a 6% fat diet". This is not in line with the information given
in Table 1 (11 %).
Lines 154-155: "...the means of the combined high-fat groups were calculated". I
do not think that this is correct because it ignores a potential impact of the fat
quality.
Line 168: "...fat quality had a pronounced effect" (see above).
Line 156ff: I still think that a two-way ANOVA would be correct. Is the outcome of
the analysis different between a one-way and a two-way ANOVA?
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: Yes, and I have assessed the statistics in my report.
assistant