Reviewer ’s report  
 
Title: Rate and determinants of non -adherence to a gluten -free diet and nutritional status 
assessment in children and adolescents with celiac disease in a tertiary Brazilian referral center: a 
cross -sectional and retrospective study.  
 
Version: 1 Date: 01 Nov 2017  
 
Reviewer: Diana Sacchi  
 
Reviewer's report:  
 
Dear Authors,  
 
This is a well -written article that does identify an important gap in Celiac Disease (CD) 
treatment in children and a current "hot topic" in daily clinical practice in CD. However, to make 
this paper publishable, I would suggest the authors need to review the article due  to the presence 
of some linguistic errors (e.g. GDF instead of GFD in the abstract). Moreover, in the discussion 
the authors could strengthen the importance of the education on CD and the adherence of a GFD 
not only to the pediatric patients but also to t he parents as well, due to the fact that most of the 
questionnaires are obviously answered by the mothers.  
 
Your sincerely,  
Diana Sacchi.  
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
Yes 
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
No 
 
Are the conclusions drawn adequately supported by  the data shown?  
If not, please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in the manuscript or would you recommend an  
additional statistical review?  
If an additional statistical review is recommended, please specify  what aspects require further  
assessment in your comments to the editors.  
 
I am able to assess the statistics  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Needs some language corrections before being published  
 
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following questions:  
 
1. Have you in the past five years received reimbursements, fees, funding, or salary from an  
organisation that may in any way gain  or lose financially from the publication of this  
manuscript, either now or in the future?  
 
2. Do you hold any stocks or shares in an organisation that may in any way gain or lose  
financially from the publication of this manuscript, either now or in the fut ure? 
 
3. Do you hold or are you currently applying for any patents relating to the content of the  
manuscript?  
 
4. Have you received reimbursements, fees, funding, or salary from an organization that 
holds  or has applied for patents relating to the content of  the manuscript?  
 
5. Do you have any other financial competing interests?  
 
6. Do you have any non -financial competing interests in relation to this paper?  
 
If you can answer no to all of the above, write 'I declare that I have no competing interests' 
below.  If your reply is yes to any, please give details below.  
 
I declare I have no competing interests.  
 
I agree to the open peer review policy of the journal. I understand that my name will be included  
on my report to the authors and, if the manuscript is accepted  for publication, my named report  
including any attachments I upload will be posted on the website along with the authors'  
responses. I agree for my report to be made available under an Open Access Creative Commons  
CC-BY license ( http://creativecommons.org /licenses/by/4.0/ ). I understand that any comments  
which I do not wish to be included in my named report can be included as confidential comments  
to the editors, which will not be published.  
 
I agree to the open peer review policy of the journal  
Reviewer ’s report  
 
Title: Rate and determinants of non -adherence to a gluten -free diet and nutritional status 
assessment in children and adolescents with celiac disease in a tertiary Brazilian referral center: a 
cross -sectional and retrospective study.  
 
Version: 1 Date: 01 Nov 2017  
 
Reviewer: Diana Sacchi  
 
Reviewer's report:  
 
Dear Authors,  
 
This is a well -written article that does identify an important gap in Celiac Disease (CD) 
treatment in children and a current "hot topic" in daily clinical practice in CD. However, to make 
this paper publishable, I would suggest the authors need to review the article due  to the presence 
of some linguistic errors (e.g. GDF instead of GFD in the abstract). Moreover, in the discussion 
the authors could strengthen the importance of the education on CD and the adherence of a GFD 
not only to the pediatric patients but also to t he parents as well, due to the fact that most of the 
questionnaires are obviously answered by the mothers.  
 
Your sincerely,  
Diana Sacchi.  
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
Yes 
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
No 
 
Are the conclusions drawn adequately supported by  the data shown?  
If not, please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in the manuscript or would you recommend an  
additional statistical review?  
If an additional statistical review is recommended, please specify  what aspects require further  
assessment in your comments to the editors.  
 
I am able to assess the statistics  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Needs some language corrections before being published  
 
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following questions:  
 
1. Have you in the past five years received reimbursements, fees, funding, or salary from an  
organisation that may in any way gain  or lose financially from the publication of this  
manuscript, either now or in the future?  
 
2. Do you hold any stocks or shares in an organisation that may in any way gain or lose  
financially from the publication of this manuscript, either now or in the fut ure? 
 
3. Do you hold or are you currently applying for any patents relating to the content of the  
manuscript?  
 
4. Have you received reimbursements, fees, funding, or salary from an organization that 
holds  or has applied for patents relating to the content of  the manuscript?  
 
5. Do you have any other financial competing interests?  
 
6. Do you have any non -financial competing interests in relation to this paper?  
 
If you can answer no to all of the above, write 'I declare that I have no competing interests' 
below.  If your reply is yes to any, please give details below.  
 
I declare I have no competing interests.  
 
I agree to the open peer review policy of the journal. I understand that my name will be included  
on my report to the authors and, if the manuscript is accepted  for publication, my named report  
including any attachments I upload will be posted on the website along with the authors'  
responses. I agree for my report to be made available under an Open Access Creative Commons  
CC-BY license ( http://creativecommons.org /licenses/by/4.0/ ). I understand that any comments  
which I do not wish to be included in my named report can be included as confidential comments  
to the editors, which will not be published.  
 
I agree to the open peer review policy of the journal  
Please review this paper.
user
Reviewer ’s report  
 
Title: Rate and determinants of non -adherence to a gluten -free diet and nutritional status 
assessment in children and adolescents with celiac disease in a tertiary Brazilian referral center: a 
cross -sectional and retrospective study.  
 
Version: 1 Date: 01 Nov 2017  
 
Reviewer: Diana Sacchi  
 
Reviewer's report:  
 
Dear Authors,  
 
This is a well -written article that does identify an important gap in Celiac Disease (CD) 
treatment in children and a current "hot topic" in daily clinical practice in CD. However, to make 
this paper publishable, I would suggest the authors need to review the article due  to the presence 
of some linguistic errors (e.g. GDF instead of GFD in the abstract). Moreover, in the discussion 
the authors could strengthen the importance of the education on CD and the adherence of a GFD 
not only to the pediatric patients but also to t he parents as well, due to the fact that most of the 
questionnaires are obviously answered by the mothers.  
 
Your sincerely,  
Diana Sacchi.  
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
Yes 
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
No 
 
Are the conclusions drawn adequately supported by  the data shown?  
If not, please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in the manuscript or would you recommend an  
additional statistical review?  
If an additional statistical review is recommended, please specify  what aspects require further  
assessment in your comments to the editors.  
 
I am able to assess the statistics  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Needs some language corrections before being published  
 
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following questions:  
 
1. Have you in the past five years received reimbursements, fees, funding, or salary from an  
organisation that may in any way gain  or lose financially from the publication of this  
manuscript, either now or in the future?  
 
2. Do you hold any stocks or shares in an organisation that may in any way gain or lose  
financially from the publication of this manuscript, either now or in the fut ure? 
 
3. Do you hold or are you currently applying for any patents relating to the content of the  
manuscript?  
 
4. Have you received reimbursements, fees, funding, or salary from an organization that 
holds  or has applied for patents relating to the content of  the manuscript?  
 
5. Do you have any other financial competing interests?  
 
6. Do you have any non -financial competing interests in relation to this paper?  
 
If you can answer no to all of the above, write 'I declare that I have no competing interests' 
below.  If your reply is yes to any, please give details below.  
 
I declare I have no competing interests.  
 
I agree to the open peer review policy of the journal. I understand that my name will be included  
on my report to the authors and, if the manuscript is accepted  for publication, my named report  
including any attachments I upload will be posted on the website along with the authors'  
responses. I agree for my report to be made available under an Open Access Creative Commons  
CC-BY license ( http://creativecommons.org /licenses/by/4.0/ ). I understand that any comments  
which I do not wish to be included in my named report can be included as confidential comments  
to the editors, which will not be published.  
 
I agree to the open peer review policy of the journal  
assistant