Reviewer ’s report  
 
Title: A Rare Cause of Dysphagia Due to Esophageal Intramural Pseudodiverticulosis: A Case  
Report and Review of Li terature  
 
Version: 1 Date: 16 Oct 2019  
 
Reviewer: Saikiran Raghavapuram  
 
Reviewer's report:  
 
Authors have described a rare case of esophageal intramural pseudodiverticulosis. Though its is 
rare, it is well reported in the literature.  
 
 
I have following comments/suggestions to the authors:  
 
 
1) What prompted authors to obtain barium esophagogram after the initial EGD showing severe 
esophageal stenosis? Are authors concerned about missing some other diagnosis which would be 
helped by a bariu m esophagogram?  
 
 
2) There are certain grammatical mistakes in the case report. a) On page 5, comma after "reports 
of critically ill patients" can be followed by period (full stop) and the following sentence can be 
written as "EIP was the proposed underlyin g cause of increased intraluminal pressure leading to 
esophageal perforation and pneumomediastinum is those two cases. b) On page 6, in the first 
paragraph, a period can be used in place of comma after "interconnecting and bridging to one 
another" and the following sentence can be started with "Although".  
 
 
3) Was there a follow up longer than 3 weeks on this patient to see if the dysphagia has recurred 
post dilatation?  
 
 
4) Is there any data about the chance and risks of perforation of such pseudodiverticulae post 
dilatation? Is there any data regarding bacterial infection of such pseudodiverticulae? Is there any 
data regarding the incidence of esophageal cancer in such pa tients and how often endoscopy is 
recommended for it's detection?  
 
 
 
 
 
 
 
Are the methods appropriate and well described?  
If not, pleas e specify what is required in your comments to the authors.  
 
Unable to assess  
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
Unable to assess  
 
Are the conclusions drawn adequately suppo rted by the data shown?  
If not, please explain in your comments to the authors.  
 
Unable to assess  
 
Are you able to assess any statistics in the manus cript or would you recommend an 
additional statistical review?  
If an a dditional statistical review is recommended, please speci fy what aspects require further 
assessment in your comments to the editors.  
 
Not relevant to this manuscript  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Needs some language corrections before being published  
 
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following questions:  
 
1. Have you in the past five years received reimbursements, f ees, funding, or salary from an 
organisation that may in any way gain or lose financially from the publi cation of this 
manuscript, either now or in the future?  
 
2. Do you hold any stocks or shares in an organisation t hat may in any way gain or lose 
financially from the publication of this manuscript, either now or in the future?  
 
3. Do you hold or are you curr ently applying for any patents  relating to the content of the 
manuscript?  
 
4. Have you received reimbursements, fees, funding, or salary from an organization that 
holds or has applied for patents relating to the content of the manuscript?  
 
5. Do you have any  other financial competing interests?  
 
6. Do you have any non -financial competing interests in relation to this paper?  
If you can answer no to all of the above, write 'I declare that I have  no competing interests' 
below. If your reply is yes to any, please give details below.  
 
I declare that I have no competing interests  
 
I agree to the open peer review policy of the journal. I understan d that my name will be included 
on my report to the authors and, if the manuscript is accepted for publication, my named repo rt 
including any attachments I upload will be posted on the website along with the authors' 
responses. I agree for my report to be made available under an Open Access Creative Commons 
CC-BY license ( http://creativecommons.org/licenses/by/4.0/ ). I understan d that any comments 
which I do not wish to be included in my named report can be in cluded as confidential comments 
to the editors, which will not be published.  
 
I agree to the open peer review policy of the journal  
Reviewer ’s report  
 
Title: A Rare Cause of Dysphagia Due to Esophageal Intramural Pseudodiverticulosis: A Case  
Report and Review of Li terature  
 
Version: 1 Date: 16 Oct 2019  
 
Reviewer: Saikiran Raghavapuram  
 
Reviewer's report:  
 
Authors have described a rare case of esophageal intramural pseudodiverticulosis. Though its is 
rare, it is well reported in the literature.  
 
 
I have following comments/suggestions to the authors:  
 
 
1) What prompted authors to obtain barium esophagogram after the initial EGD showing severe 
esophageal stenosis? Are authors concerned about missing some other diagnosis which would be 
helped by a bariu m esophagogram?  
 
 
2) There are certain grammatical mistakes in the case report. a) On page 5, comma after "reports 
of critically ill patients" can be followed by period (full stop) and the following sentence can be 
written as "EIP was the proposed underlyin g cause of increased intraluminal pressure leading to 
esophageal perforation and pneumomediastinum is those two cases. b) On page 6, in the first 
paragraph, a period can be used in place of comma after "interconnecting and bridging to one 
another" and the following sentence can be started with "Although".  
 
 
3) Was there a follow up longer than 3 weeks on this patient to see if the dysphagia has recurred 
post dilatation?  
 
 
4) Is there any data about the chance and risks of perforation of such pseudodiverticulae post 
dilatation? Is there any data regarding bacterial infection of such pseudodiverticulae? Is there any 
data regarding the incidence of esophageal cancer in such pa tients and how often endoscopy is 
recommended for it's detection?  
 
 
 
 
 
 
 
Are the methods appropriate and well described?  
If not, pleas e specify what is required in your comments to the authors.  
 
Unable to assess  
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
Unable to assess  
 
Are the conclusions drawn adequately suppo rted by the data shown?  
If not, please explain in your comments to the authors.  
 
Unable to assess  
 
Are you able to assess any statistics in the manus cript or would you recommend an 
additional statistical review?  
If an a dditional statistical review is recommended, please speci fy what aspects require further 
assessment in your comments to the editors.  
 
Not relevant to this manuscript  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Needs some language corrections before being published  
 
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following questions:  
 
1. Have you in the past five years received reimbursements, f ees, funding, or salary from an 
organisation that may in any way gain or lose financially from the publi cation of this 
manuscript, either now or in the future?  
 
2. Do you hold any stocks or shares in an organisation t hat may in any way gain or lose 
financially from the publication of this manuscript, either now or in the future?  
 
3. Do you hold or are you curr ently applying for any patents  relating to the content of the 
manuscript?  
 
4. Have you received reimbursements, fees, funding, or salary from an organization that 
holds or has applied for patents relating to the content of the manuscript?  
 
5. Do you have any  other financial competing interests?  
 
6. Do you have any non -financial competing interests in relation to this paper?  
If you can answer no to all of the above, write 'I declare that I have  no competing interests' 
below. If your reply is yes to any, please give details below.  
 
I declare that I have no competing interests  
 
I agree to the open peer review policy of the journal. I understan d that my name will be included 
on my report to the authors and, if the manuscript is accepted for publication, my named repo rt 
including any attachments I upload will be posted on the website along with the authors' 
responses. I agree for my report to be made available under an Open Access Creative Commons 
CC-BY license ( http://creativecommons.org/licenses/by/4.0/ ). I understan d that any comments 
which I do not wish to be included in my named report can be in cluded as confidential comments 
to the editors, which will not be published.  
 
I agree to the open peer review policy of the journal  
Please review this paper.
user
Reviewer ’s report  
 
Title: A Rare Cause of Dysphagia Due to Esophageal Intramural Pseudodiverticulosis: A Case  
Report and Review of Li terature  
 
Version: 1 Date: 16 Oct 2019  
 
Reviewer: Saikiran Raghavapuram  
 
Reviewer's report:  
 
Authors have described a rare case of esophageal intramural pseudodiverticulosis. Though its is 
rare, it is well reported in the literature.  
 
 
I have following comments/suggestions to the authors:  
 
 
1) What prompted authors to obtain barium esophagogram after the initial EGD showing severe 
esophageal stenosis? Are authors concerned about missing some other diagnosis which would be 
helped by a bariu m esophagogram?  
 
 
2) There are certain grammatical mistakes in the case report. a) On page 5, comma after "reports 
of critically ill patients" can be followed by period (full stop) and the following sentence can be 
written as "EIP was the proposed underlyin g cause of increased intraluminal pressure leading to 
esophageal perforation and pneumomediastinum is those two cases. b) On page 6, in the first 
paragraph, a period can be used in place of comma after "interconnecting and bridging to one 
another" and the following sentence can be started with "Although".  
 
 
3) Was there a follow up longer than 3 weeks on this patient to see if the dysphagia has recurred 
post dilatation?  
 
 
4) Is there any data about the chance and risks of perforation of such pseudodiverticulae post 
dilatation? Is there any data regarding bacterial infection of such pseudodiverticulae? Is there any 
data regarding the incidence of esophageal cancer in such pa tients and how often endoscopy is 
recommended for it's detection?  
 
 
 
 
 
 
 
Are the methods appropriate and well described?  
If not, pleas e specify what is required in your comments to the authors.  
 
Unable to assess  
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
Unable to assess  
 
Are the conclusions drawn adequately suppo rted by the data shown?  
If not, please explain in your comments to the authors.  
 
Unable to assess  
 
Are you able to assess any statistics in the manus cript or would you recommend an 
additional statistical review?  
If an a dditional statistical review is recommended, please speci fy what aspects require further 
assessment in your comments to the editors.  
 
Not relevant to this manuscript  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Needs some language corrections before being published  
 
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following questions:  
 
1. Have you in the past five years received reimbursements, f ees, funding, or salary from an 
organisation that may in any way gain or lose financially from the publi cation of this 
manuscript, either now or in the future?  
 
2. Do you hold any stocks or shares in an organisation t hat may in any way gain or lose 
financially from the publication of this manuscript, either now or in the future?  
 
3. Do you hold or are you curr ently applying for any patents  relating to the content of the 
manuscript?  
 
4. Have you received reimbursements, fees, funding, or salary from an organization that 
holds or has applied for patents relating to the content of the manuscript?  
 
5. Do you have any  other financial competing interests?  
 
6. Do you have any non -financial competing interests in relation to this paper?  
If you can answer no to all of the above, write 'I declare that I have  no competing interests' 
below. If your reply is yes to any, please give details below.  
 
I declare that I have no competing interests  
 
I agree to the open peer review policy of the journal. I understan d that my name will be included 
on my report to the authors and, if the manuscript is accepted for publication, my named repo rt 
including any attachments I upload will be posted on the website along with the authors' 
responses. I agree for my report to be made available under an Open Access Creative Commons 
CC-BY license ( http://creativecommons.org/licenses/by/4.0/ ). I understan d that any comments 
which I do not wish to be included in my named report can be in cluded as confidential comments 
to the editors, which will not be published.  
 
I agree to the open peer review policy of the journal  
assistant