Title: The Patient Perspective on Transanal Irrigation Treatment for Low Anterior Resection
Syndrome after Rectal Cancer Surgery -A Qualitative and Quantitative Study
Version: 1 Date: 10 Dec 2024
Reviewer:  Audrius Dulskas
Reviewer's report:
Dear Authors,
I would like to thank you with this great study.
Few comments
ABSTRACT
--well written
INTRODUCTION
--well written. Just, I would include the long-term effect of LARS (ulskas A, Kavaliauskas P,
Pilipavicius L, Jodinskas M, Mikalonis M, Samalavicius NE. Long-term bowel dysfunction
following low anterior resection. Sci Rep. 2020 Jul 17;10(1):11882.  and  Chen TY, Wiltink LM,
Nout RA, Meershoek-Klein Kranenbarg E, Laurberg S, Marijnen CA, van de Velde CJ. Bowel
function 14 years after preoperative short-course radiotherapy and total mesorectal excision for
rectal cancer: report of a multicenter randomized trial. Clin. Colorectal Cancer. 2015;14:106–
114.)
METHODS
--was anybody blinded for the results? I suppose during the interviewing process it could not
be done.
--what was the treatment for control group?
RESULTS
--why was the ileostomy take down so late?
--were patients using any other treatment after the initial study: biofeedback, medication, diet,
etc
--what was the percentage of drop off?
DISCUSSION
--well written
--drop off is a significant  limitation
Title: The Patient Perspective on Transanal Irrigation Treatment for Low Anterior Resection
Syndrome after Rectal Cancer Surgery -A Qualitative and Quantitative Study
Version: 1 Date: 10 Dec 2024
Reviewer:  Audrius Dulskas
Reviewer's report:
Dear Authors,
I would like to thank you with this great study.
Few comments
ABSTRACT
--well written
INTRODUCTION
--well written. Just, I would include the long-term effect of LARS (ulskas A, Kavaliauskas P,
Pilipavicius L, Jodinskas M, Mikalonis M, Samalavicius NE. Long-term bowel dysfunction
following low anterior resection. Sci Rep. 2020 Jul 17;10(1):11882.  and  Chen TY, Wiltink LM,
Nout RA, Meershoek-Klein Kranenbarg E, Laurberg S, Marijnen CA, van de Velde CJ. Bowel
function 14 years after preoperative short-course radiotherapy and total mesorectal excision for
rectal cancer: report of a multicenter randomized trial. Clin. Colorectal Cancer. 2015;14:106–
114.)
METHODS
--was anybody blinded for the results? I suppose during the interviewing process it could not
be done.
--what was the treatment for control group?
RESULTS
--why was the ileostomy take down so late?
--were patients using any other treatment after the initial study: biofeedback, medication, diet,
etc
--what was the percentage of drop off?
DISCUSSION
--well written
--drop off is a significant  limitation
Please review this paper.
user
Title: The Patient Perspective on Transanal Irrigation Treatment for Low Anterior Resection
Syndrome after Rectal Cancer Surgery -A Qualitative and Quantitative Study
Version: 1 Date: 10 Dec 2024
Reviewer:  Audrius Dulskas
Reviewer's report:
Dear Authors,
I would like to thank you with this great study.
Few comments
ABSTRACT
--well written
INTRODUCTION
--well written. Just, I would include the long-term effect of LARS (ulskas A, Kavaliauskas P,
Pilipavicius L, Jodinskas M, Mikalonis M, Samalavicius NE. Long-term bowel dysfunction
following low anterior resection. Sci Rep. 2020 Jul 17;10(1):11882.  and  Chen TY, Wiltink LM,
Nout RA, Meershoek-Klein Kranenbarg E, Laurberg S, Marijnen CA, van de Velde CJ. Bowel
function 14 years after preoperative short-course radiotherapy and total mesorectal excision for
rectal cancer: report of a multicenter randomized trial. Clin. Colorectal Cancer. 2015;14:106–
114.)
METHODS
--was anybody blinded for the results? I suppose during the interviewing process it could not
be done.
--what was the treatment for control group?
RESULTS
--why was the ileostomy take down so late?
--were patients using any other treatment after the initial study: biofeedback, medication, diet,
etc
--what was the percentage of drop off?
DISCUSSION
--well written
--drop off is a significant  limitation
assistant