Title: SASE, Success and Adverse Event Score in Endoscopic Retrograde
Cholangiopancreatography. A Novel Grading System
Version: 3 Date: 28 May 2023
Reviewer's report:
Congratulations to the authors on this multi centre prospective cohort study which consisted of
an impressive sample size of 16327 ERCP procedures. The ASGE grading system has indeed
been developed some years ago and needs frequent evaluation and updating.
In this cohort study, the authors used this database to validate the ASGE grading system and
noted discrepancies and inaccuracies in the system. The authors also suggested a novel grading
score SASE with a correct prediction of cannulation at 92.6%, AEE at 96.5% and bleeding at
96.3%.
suggestions:
1. in general when testing a new screening tool, an ROC curve is generated to show the sensitivity
and specificities. In the validation cohort section of results, perhaps more robust statistical data
needs to be shown.
2. table 2 and table 3 are very long and takes up a lot of space. perhaps it can be shortened, or
put into the appendix section.
Title: SASE, Success and Adverse Event Score in Endoscopic Retrograde
Cholangiopancreatography. A Novel Grading System
Version: 3 Date: 28 May 2023
Reviewer's report:
Congratulations to the authors on this multi centre prospective cohort study which consisted of
an impressive sample size of 16327 ERCP procedures. The ASGE grading system has indeed
been developed some years ago and needs frequent evaluation and updating.
In this cohort study, the authors used this database to validate the ASGE grading system and
noted discrepancies and inaccuracies in the system. The authors also suggested a novel grading
score SASE with a correct prediction of cannulation at 92.6%, AEE at 96.5% and bleeding at
96.3%.
suggestions:
1. in general when testing a new screening tool, an ROC curve is generated to show the sensitivity
and specificities. In the validation cohort section of results, perhaps more robust statistical data
needs to be shown.
2. table 2 and table 3 are very long and takes up a lot of space. perhaps it can be shortened, or
put into the appendix section.
Please review this paper.
user
Title: SASE, Success and Adverse Event Score in Endoscopic Retrograde
Cholangiopancreatography. A Novel Grading System
Version: 3 Date: 28 May 2023
Reviewer's report:
Congratulations to the authors on this multi centre prospective cohort study which consisted of
an impressive sample size of 16327 ERCP procedures. The ASGE grading system has indeed
been developed some years ago and needs frequent evaluation and updating.
In this cohort study, the authors used this database to validate the ASGE grading system and
noted discrepancies and inaccuracies in the system. The authors also suggested a novel grading
score SASE with a correct prediction of cannulation at 92.6%, AEE at 96.5% and bleeding at
96.3%.
suggestions:
1. in general when testing a new screening tool, an ROC curve is generated to show the sensitivity
and specificities. In the validation cohort section of results, perhaps more robust statistical data
needs to be shown.
2. table 2 and table 3 are very long and takes up a lot of space. perhaps it can be shortened, or
put into the appendix section.
assistant