Title: Triglyceride Glucose-Waist Circumference: The Optimum Index to Screen Nonalcoholic
Fatty Liver Disease in Non-obese Adults
Version: 4 Date: 07 Aug 2023
Reviewer's report:
PEER REVIEWER ASSESSMENTS:
OBJECTIVE - Full research articles: is there a clear objective that addresses one or several
testable research questions? (Brief or other article types: is there a clear objective?)
Yes - there is a clear objective
DESIGN - Is the current approach (including controls and analysis protocols) appropriate for
the objective?
Yes - the approach is appropriate
EXECUTION - Are the experiments and analyses performed with sufficient technical rigor to
allow confidence in the results?
Yes - experiments and analyses were performed appropriately
STATISTICS - Is the use of statistics in the manuscript appropriate?
Yes - appropriate statistical analyses have been used in the study
INTERPRETATION - Is the current interpretation/discussion of the results reasonable and not
overstated?
Yes - the author's interpretation is reasonable
OVERALL MANUSCRIPT POTENTIAL - Has the author addressed your concerns sufficiently
for you to now recommend the work as a technically sound contribution? If not, can further
revisions be made to make the work technically sound?
Yes - current version is technically sound
PEER REVIEWER COMMENTS:
GENERAL COMMENTS: This is an interesting MS, and authors did good job on revision.
Simplified measures to access liver pathology are much needed in situations when biopsy is not
indicated (i.e. non obese adults).
ADDITIONAL REQUESTS/SUGGESTIONS:
pleas do small revisions for grammar and structure (MS does not need re-reviewing another
time).
"Fibroscan is a non-invasive way to assess hepatic steatosis [control attenuation parameters
(CAP)] and liver stiffness measurement" change to "Fibroscan is a non-invasive way to assess
hepatic steatosis [by control attenuation parameters (CAP)] and fibrosis [by liver stiffness
measurement  (LSM)].
"The correlations of CAP and LSM to the indexes were conducted by generalized linear models".
change to " "The correlations of CAP and LSM to the indexes were assessed by generalized
linear models."
"The positive association was existed between TG/HDL-c and TyG-WC  .." change to "The
positive association was detected for TG/HDL-c and TyG-WC "
"TyG-WC was positive related .." change to "TyG-WC were positively associated with ...
In Conclusion of Abstract, please chane past tense to Present tense  (were to are)
Title: Triglyceride Glucose-Waist Circumference: The Optimum Index to Screen Nonalcoholic
Fatty Liver Disease in Non-obese Adults
Version: 4 Date: 07 Aug 2023
Reviewer's report:
PEER REVIEWER ASSESSMENTS:
OBJECTIVE - Full research articles: is there a clear objective that addresses one or several
testable research questions? (Brief or other article types: is there a clear objective?)
Yes - there is a clear objective
DESIGN - Is the current approach (including controls and analysis protocols) appropriate for
the objective?
Yes - the approach is appropriate
EXECUTION - Are the experiments and analyses performed with sufficient technical rigor to
allow confidence in the results?
Yes - experiments and analyses were performed appropriately
STATISTICS - Is the use of statistics in the manuscript appropriate?
Yes - appropriate statistical analyses have been used in the study
INTERPRETATION - Is the current interpretation/discussion of the results reasonable and not
overstated?
Yes - the author's interpretation is reasonable
OVERALL MANUSCRIPT POTENTIAL - Has the author addressed your concerns sufficiently
for you to now recommend the work as a technically sound contribution? If not, can further
revisions be made to make the work technically sound?
Yes - current version is technically sound
PEER REVIEWER COMMENTS:
GENERAL COMMENTS: This is an interesting MS, and authors did good job on revision.
Simplified measures to access liver pathology are much needed in situations when biopsy is not
indicated (i.e. non obese adults).
ADDITIONAL REQUESTS/SUGGESTIONS:
pleas do small revisions for grammar and structure (MS does not need re-reviewing another
time).
"Fibroscan is a non-invasive way to assess hepatic steatosis [control attenuation parameters
(CAP)] and liver stiffness measurement" change to "Fibroscan is a non-invasive way to assess
hepatic steatosis [by control attenuation parameters (CAP)] and fibrosis [by liver stiffness
measurement  (LSM)].
"The correlations of CAP and LSM to the indexes were conducted by generalized linear models".
change to " "The correlations of CAP and LSM to the indexes were assessed by generalized
linear models."
"The positive association was existed between TG/HDL-c and TyG-WC  .." change to "The
positive association was detected for TG/HDL-c and TyG-WC "
"TyG-WC was positive related .." change to "TyG-WC were positively associated with ...
In Conclusion of Abstract, please chane past tense to Present tense  (were to are)
Please review this paper.
user
Title: Triglyceride Glucose-Waist Circumference: The Optimum Index to Screen Nonalcoholic
Fatty Liver Disease in Non-obese Adults
Version: 4 Date: 07 Aug 2023
Reviewer's report:
PEER REVIEWER ASSESSMENTS:
OBJECTIVE - Full research articles: is there a clear objective that addresses one or several
testable research questions? (Brief or other article types: is there a clear objective?)
Yes - there is a clear objective
DESIGN - Is the current approach (including controls and analysis protocols) appropriate for
the objective?
Yes - the approach is appropriate
EXECUTION - Are the experiments and analyses performed with sufficient technical rigor to
allow confidence in the results?
Yes - experiments and analyses were performed appropriately
STATISTICS - Is the use of statistics in the manuscript appropriate?
Yes - appropriate statistical analyses have been used in the study
INTERPRETATION - Is the current interpretation/discussion of the results reasonable and not
overstated?
Yes - the author's interpretation is reasonable
OVERALL MANUSCRIPT POTENTIAL - Has the author addressed your concerns sufficiently
for you to now recommend the work as a technically sound contribution? If not, can further
revisions be made to make the work technically sound?
Yes - current version is technically sound
PEER REVIEWER COMMENTS:
GENERAL COMMENTS: This is an interesting MS, and authors did good job on revision.
Simplified measures to access liver pathology are much needed in situations when biopsy is not
indicated (i.e. non obese adults).
ADDITIONAL REQUESTS/SUGGESTIONS:
pleas do small revisions for grammar and structure (MS does not need re-reviewing another
time).
"Fibroscan is a non-invasive way to assess hepatic steatosis [control attenuation parameters
(CAP)] and liver stiffness measurement" change to "Fibroscan is a non-invasive way to assess
hepatic steatosis [by control attenuation parameters (CAP)] and fibrosis [by liver stiffness
measurement  (LSM)].
"The correlations of CAP and LSM to the indexes were conducted by generalized linear models".
change to " "The correlations of CAP and LSM to the indexes were assessed by generalized
linear models."
"The positive association was existed between TG/HDL-c and TyG-WC  .." change to "The
positive association was detected for TG/HDL-c and TyG-WC "
"TyG-WC was positive related .." change to "TyG-WC were positively associated with ...
In Conclusion of Abstract, please chane past tense to Present tense  (were to are)
assistant