Title: Incidence and Risk of Remnant Gastric Cancer after Gastrectomy for Gastric Cancer: A
Population-Based Study from the SEER Database
Version: 0 Date: 21 Dec 2023
Reviewer:  Akira Umemura
Reviewer's report:
The authors have demonstrated that the cumulative incidence of RGCs was 1.88% at 20
years after GC gastrectomy in the U.S. population. In addition,  multivariate analyses also
demonstrated that older age, male sex, marital status, lower income, and invasion depth are
independent risk factors for RGC development. These results are informative for readers
involved in GC treatments. There are some suggestions requiring revision.
1. Please make a table of  discussion in Line 207-221. Provided table can also visualize and
emphasize your results.
2.   Line 240-245, de novo GC in male is relatively leap of logic, this phenomenon can not be
explained by this mechanism.  For examples, marital status, lower income and smoking habit
are related to social problems of lost surveillance in these patients.
3. You have to mention about H. pylori infection in RGC patients citing prior publications more
in detail.
Title: Incidence and Risk of Remnant Gastric Cancer after Gastrectomy for Gastric Cancer: A
Population-Based Study from the SEER Database
Version: 0 Date: 21 Dec 2023
Reviewer:  Akira Umemura
Reviewer's report:
The authors have demonstrated that the cumulative incidence of RGCs was 1.88% at 20
years after GC gastrectomy in the U.S. population. In addition,  multivariate analyses also
demonstrated that older age, male sex, marital status, lower income, and invasion depth are
independent risk factors for RGC development. These results are informative for readers
involved in GC treatments. There are some suggestions requiring revision.
1. Please make a table of  discussion in Line 207-221. Provided table can also visualize and
emphasize your results.
2.   Line 240-245, de novo GC in male is relatively leap of logic, this phenomenon can not be
explained by this mechanism.  For examples, marital status, lower income and smoking habit
are related to social problems of lost surveillance in these patients.
3. You have to mention about H. pylori infection in RGC patients citing prior publications more
in detail.
Please review this paper.
user
Title: Incidence and Risk of Remnant Gastric Cancer after Gastrectomy for Gastric Cancer: A
Population-Based Study from the SEER Database
Version: 0 Date: 21 Dec 2023
Reviewer:  Akira Umemura
Reviewer's report:
The authors have demonstrated that the cumulative incidence of RGCs was 1.88% at 20
years after GC gastrectomy in the U.S. population. In addition,  multivariate analyses also
demonstrated that older age, male sex, marital status, lower income, and invasion depth are
independent risk factors for RGC development. These results are informative for readers
involved in GC treatments. There are some suggestions requiring revision.
1. Please make a table of  discussion in Line 207-221. Provided table can also visualize and
emphasize your results.
2.   Line 240-245, de novo GC in male is relatively leap of logic, this phenomenon can not be
explained by this mechanism.  For examples, marital status, lower income and smoking habit
are related to social problems of lost surveillance in these patients.
3. You have to mention about H. pylori infection in RGC patients citing prior publications more
in detail.
assistant