Reviewer's report
Title:Increased proton pump inhibitor and NSAID exposure in irritable bowel
syndrome: results from a case-control study
Version: 3Date:28 July 2012
Reviewer: saurabh mukewar
Reviewer's report:
Addressed issue of duration of exposure prior to onset of symptoms.
Other comments:
ABSTRACT
Results: Should add a statement that PPI use was not significantly correlated
after controlling for dyspepsia. - made necessary changes to abstract.
METHODS
“In other cases, diagnosis according to Rome III criteria (symptoms for at
least 6 months) was confirmed using questionnaires sent to patients to assess
symptom duration
following initial symptom onset.” – Unclear what this means. Were these cases
with <6 month history of IBS symptoms. - addressed
“The control group consisted of 408 individuals randomly selected from the
general population in
Maastricht, the Netherlands” – Were there 287 controls or 408 controls?
- addressed
Level of interest: An article of limited interest
Quality of written English: Acceptable
Statistical review: Yes, and I have assessed the statistics in my report.
Reviewer's report
Title:Increased proton pump inhibitor and NSAID exposure in irritable bowel
syndrome: results from a case-control study
Version: 3Date:28 July 2012
Reviewer: saurabh mukewar
Reviewer's report:
Addressed issue of duration of exposure prior to onset of symptoms.
Other comments:
ABSTRACT
Results: Should add a statement that PPI use was not significantly correlated
after controlling for dyspepsia. - made necessary changes to abstract.
METHODS
“In other cases, diagnosis according to Rome III criteria (symptoms for at
least 6 months) was confirmed using questionnaires sent to patients to assess
symptom duration
following initial symptom onset.” – Unclear what this means. Were these cases
with <6 month history of IBS symptoms. - addressed
“The control group consisted of 408 individuals randomly selected from the
general population in
Maastricht, the Netherlands” – Were there 287 controls or 408 controls?
- addressed
Level of interest: An article of limited interest
Quality of written English: Acceptable
Statistical review: Yes, and I have assessed the statistics in my report.
Please review this paper.
user
Reviewer's report
Title:Increased proton pump inhibitor and NSAID exposure in irritable bowel
syndrome: results from a case-control study
Version: 3Date:28 July 2012
Reviewer: saurabh mukewar
Reviewer's report:
Addressed issue of duration of exposure prior to onset of symptoms.
Other comments:
ABSTRACT
Results: Should add a statement that PPI use was not significantly correlated
after controlling for dyspepsia. - made necessary changes to abstract.
METHODS
“In other cases, diagnosis according to Rome III criteria (symptoms for at
least 6 months) was confirmed using questionnaires sent to patients to assess
symptom duration
following initial symptom onset.” – Unclear what this means. Were these cases
with <6 month history of IBS symptoms. - addressed
“The control group consisted of 408 individuals randomly selected from the
general population in
Maastricht, the Netherlands” – Were there 287 controls or 408 controls?
- addressed
Level of interest: An article of limited interest
Quality of written English: Acceptable
Statistical review: Yes, and I have assessed the statistics in my report.
assistant