Title: Long-term prognosis of patients with hepatitis B virus-related acute-on-chronic liver
failure: a retrospective study
Version: 3 Date: 09 Feb 2022
Reviewer's report:
Dear Authors
I have following comments and suggestions for your manuscript:
1. Since their was increased 90 day mortality noted in the study, it is better to incorporate ACLF
survival models : AARC score (APASL ACLF score) and or CLIF-SOFA score in the results
and final analysis. Please add these scores if possible and make a comparison based on the scores
and final outcomes.
2. Please add a detailed analysis on the time line of the patient recruitment. It is clear that the
recruitment finished in 2020 but it is not clear when was the last patient inducted (onset of ACLF)
Title: Long-term prognosis of patients with hepatitis B virus-related acute-on-chronic liver
failure: a retrospective study
Version: 3 Date: 09 Feb 2022
Reviewer's report:
Dear Authors
I have following comments and suggestions for your manuscript:
1. Since their was increased 90 day mortality noted in the study, it is better to incorporate ACLF
survival models : AARC score (APASL ACLF score) and or CLIF-SOFA score in the results
and final analysis. Please add these scores if possible and make a comparison based on the scores
and final outcomes.
2. Please add a detailed analysis on the time line of the patient recruitment. It is clear that the
recruitment finished in 2020 but it is not clear when was the last patient inducted (onset of ACLF)
Please review this paper.
user
Title: Long-term prognosis of patients with hepatitis B virus-related acute-on-chronic liver
failure: a retrospective study
Version: 3 Date: 09 Feb 2022
Reviewer's report:
Dear Authors
I have following comments and suggestions for your manuscript:
1. Since their was increased 90 day mortality noted in the study, it is better to incorporate ACLF
survival models : AARC score (APASL ACLF score) and or CLIF-SOFA score in the results
and final analysis. Please add these scores if possible and make a comparison based on the scores
and final outcomes.
2. Please add a detailed analysis on the time line of the patient recruitment. It is clear that the
recruitment finished in 2020 but it is not clear when was the last patient inducted (onset of ACLF)
assistant