Reviewer's report
Title:Unexplained Chest/Epigastric Pain in Patients with Normal Endoscopy as a
Predictor for Ischemic Heart Disease and Mortality: A Danish 10-Year Cohort
Study
Version: 6Date:9 April 2008
Reviewer: Noel Bairey Merz
Reviewer's report:
The manuscript is overall responsive to the prior review. The authors did not fully
respond to the first query, e.g. they did not clarify if they selected the symptom
constellation by fitting it to the outcome data and if they did this, it should be
described as a limitation and proposed to be tested in a secondary population. If
the selected their symptoms a priori this is not a problem.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: Yes, but I do not feel adequately qualified to assess the
statistics.
Declaration of competing interests:
I declare that I have no competing interests.
Reviewer's report
Title:Unexplained Chest/Epigastric Pain in Patients with Normal Endoscopy as a
Predictor for Ischemic Heart Disease and Mortality: A Danish 10-Year Cohort
Study
Version: 6Date:9 April 2008
Reviewer: Noel Bairey Merz
Reviewer's report:
The manuscript is overall responsive to the prior review. The authors did not fully
respond to the first query, e.g. they did not clarify if they selected the symptom
constellation by fitting it to the outcome data and if they did this, it should be
described as a limitation and proposed to be tested in a secondary population. If
the selected their symptoms a priori this is not a problem.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: Yes, but I do not feel adequately qualified to assess the
statistics.
Declaration of competing interests:
I declare that I have no competing interests.
Please review this paper.
user
Reviewer's report
Title:Unexplained Chest/Epigastric Pain in Patients with Normal Endoscopy as a
Predictor for Ischemic Heart Disease and Mortality: A Danish 10-Year Cohort
Study
Version: 6Date:9 April 2008
Reviewer: Noel Bairey Merz
Reviewer's report:
The manuscript is overall responsive to the prior review. The authors did not fully
respond to the first query, e.g. they did not clarify if they selected the symptom
constellation by fitting it to the outcome data and if they did this, it should be
described as a limitation and proposed to be tested in a secondary population. If
the selected their symptoms a priori this is not a problem.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: Yes, but I do not feel adequately qualified to assess the
statistics.
Declaration of competing interests:
I declare that I have no competing interests.
assistant