Title: Long term changes in thrombocytopenia and leucopenia after HCV eradication with
direct-acting antivirals
Version: 4 Date: 11 Apr 2023
Reviewer's report:
Hematological parameters ......Chronological changes in hematological parameters were
assessed in the 110 patients who achieved SVR year after HCV eradication, mean WBC count,
which was 4,034/L before DAA treatment, increased to 4,546/L (p<0.01), with the increase
maintained for 5 years (Fig. 1A). ......Evaluation of hematological parameters within 24 weeks
after DAA treatment showed that, in our department, mean WBC count, which was 4,156/#L
before DAA treatment, increased to 4,520/#L 4 weeks after DAA treatment (p<0.01) and was
maintained for the following 20 weeks (Supplementary Fig. 5A).
You initially reported the number of patients as 110, in the second part you refer only to the
figure without reporting the number of subjects examined, this creates confusion
Title: Long term changes in thrombocytopenia and leucopenia after HCV eradication with
direct-acting antivirals
Version: 4 Date: 11 Apr 2023
Reviewer's report:
Hematological parameters ......Chronological changes in hematological parameters were
assessed in the 110 patients who achieved SVR year after HCV eradication, mean WBC count,
which was 4,034/L before DAA treatment, increased to 4,546/L (p<0.01), with the increase
maintained for 5 years (Fig. 1A). ......Evaluation of hematological parameters within 24 weeks
after DAA treatment showed that, in our department, mean WBC count, which was 4,156/#L
before DAA treatment, increased to 4,520/#L 4 weeks after DAA treatment (p<0.01) and was
maintained for the following 20 weeks (Supplementary Fig. 5A).
You initially reported the number of patients as 110, in the second part you refer only to the
figure without reporting the number of subjects examined, this creates confusion
Please review this paper.
user
Title: Long term changes in thrombocytopenia and leucopenia after HCV eradication with
direct-acting antivirals
Version: 4 Date: 11 Apr 2023
Reviewer's report:
Hematological parameters ......Chronological changes in hematological parameters were
assessed in the 110 patients who achieved SVR year after HCV eradication, mean WBC count,
which was 4,034/L before DAA treatment, increased to 4,546/L (p<0.01), with the increase
maintained for 5 years (Fig. 1A). ......Evaluation of hematological parameters within 24 weeks
after DAA treatment showed that, in our department, mean WBC count, which was 4,156/#L
before DAA treatment, increased to 4,520/#L 4 weeks after DAA treatment (p<0.01) and was
maintained for the following 20 weeks (Supplementary Fig. 5A).
You initially reported the number of patients as 110, in the second part you refer only to the
figure without reporting the number of subjects examined, this creates confusion
assistant