Title: Formation of non-cholesterol gallstones in populations within clonorchiasis endemic
regions is closely related to Clonorchis sinensis infection
Version: 1 Date: 06 Mar 2025
Reviewer's report:
This article presents an interesting and important study on the association between Clonorchis
sinensis infection and the formation of gallbladder non-cholesterol stones in males in an endemic
area. The research question is relevant, and the findings contribute to our understanding of the
etiology of gallbladder stones in this specific population.
1. I noticed that the diagnosis of Clonorchis sinensis infection in the article was conducted using
the IgG antibody method, which involves a considerable amount of work. Has an effectiveness
evaluation been conducted for this method? Clinically, the microscopic examination of feces is
commonly used. If the two methods are combined, would the accuracy rate be higher?
2. The language of the article needs further refinement.
Title: Formation of non-cholesterol gallstones in populations within clonorchiasis endemic
regions is closely related to Clonorchis sinensis infection
Version: 1 Date: 06 Mar 2025
Reviewer's report:
This article presents an interesting and important study on the association between Clonorchis
sinensis infection and the formation of gallbladder non-cholesterol stones in males in an endemic
area. The research question is relevant, and the findings contribute to our understanding of the
etiology of gallbladder stones in this specific population.
1. I noticed that the diagnosis of Clonorchis sinensis infection in the article was conducted using
the IgG antibody method, which involves a considerable amount of work. Has an effectiveness
evaluation been conducted for this method? Clinically, the microscopic examination of feces is
commonly used. If the two methods are combined, would the accuracy rate be higher?
2. The language of the article needs further refinement.
Please review this paper.
user
Title: Formation of non-cholesterol gallstones in populations within clonorchiasis endemic
regions is closely related to Clonorchis sinensis infection
Version: 1 Date: 06 Mar 2025
Reviewer's report:
This article presents an interesting and important study on the association between Clonorchis
sinensis infection and the formation of gallbladder non-cholesterol stones in males in an endemic
area. The research question is relevant, and the findings contribute to our understanding of the
etiology of gallbladder stones in this specific population.
1. I noticed that the diagnosis of Clonorchis sinensis infection in the article was conducted using
the IgG antibody method, which involves a considerable amount of work. Has an effectiveness
evaluation been conducted for this method? Clinically, the microscopic examination of feces is
commonly used. If the two methods are combined, would the accuracy rate be higher?
2. The language of the article needs further refinement.
assistant