Title: Non-Alcoholic Fatty Liver Disease in Tanzania: Prevalence, Determinants, and
Diagnostic Performance of Triglycerides-Glucose Index and Triglycerides-Glucose Index –
Body Mass Index Compared to the Hepatic Ultrasound in Overweight and Obese Individuals
Version: 0 Date: 05 Jan 2024
Reviewer:  Fredirick Mashili
Reviewer's report:
The authors aimed to determine the prevalence of NFLD, its determinants and the correlation
with TyG in overweight and obese individuals in Tanzania. They report a high prevalence of
NFLD and show that TyG and TyG-BMI may be used as surrogate markers of NFLD. Generally
the study is novel given the paucity of data on NFLD in Tanzania and Africa in general. The
manuscript is very well written with a logical scientific flow and adds to the understanding of
NFLD globally. Minor revisions need to be done to further improve the manuscript.
1. Table 1 is too crowded. The authors should consider presenting only relevant data (those
which appeared significant and those required for discussion).
2. In the discussion the authors raised a very important point regarding urbanization and the
prevalence of NFLD. They however did not discuss their findings on urban rural differences in
the prevalence of NFLD. Adding this in the discussion will add more value to their findings and
generally improve the manuscript.
Title: Non-Alcoholic Fatty Liver Disease in Tanzania: Prevalence, Determinants, and
Diagnostic Performance of Triglycerides-Glucose Index and Triglycerides-Glucose Index –
Body Mass Index Compared to the Hepatic Ultrasound in Overweight and Obese Individuals
Version: 0 Date: 05 Jan 2024
Reviewer:  Fredirick Mashili
Reviewer's report:
The authors aimed to determine the prevalence of NFLD, its determinants and the correlation
with TyG in overweight and obese individuals in Tanzania. They report a high prevalence of
NFLD and show that TyG and TyG-BMI may be used as surrogate markers of NFLD. Generally
the study is novel given the paucity of data on NFLD in Tanzania and Africa in general. The
manuscript is very well written with a logical scientific flow and adds to the understanding of
NFLD globally. Minor revisions need to be done to further improve the manuscript.
1. Table 1 is too crowded. The authors should consider presenting only relevant data (those
which appeared significant and those required for discussion).
2. In the discussion the authors raised a very important point regarding urbanization and the
prevalence of NFLD. They however did not discuss their findings on urban rural differences in
the prevalence of NFLD. Adding this in the discussion will add more value to their findings and
generally improve the manuscript.
Please review this paper.
user
Title: Non-Alcoholic Fatty Liver Disease in Tanzania: Prevalence, Determinants, and
Diagnostic Performance of Triglycerides-Glucose Index and Triglycerides-Glucose Index –
Body Mass Index Compared to the Hepatic Ultrasound in Overweight and Obese Individuals
Version: 0 Date: 05 Jan 2024
Reviewer:  Fredirick Mashili
Reviewer's report:
The authors aimed to determine the prevalence of NFLD, its determinants and the correlation
with TyG in overweight and obese individuals in Tanzania. They report a high prevalence of
NFLD and show that TyG and TyG-BMI may be used as surrogate markers of NFLD. Generally
the study is novel given the paucity of data on NFLD in Tanzania and Africa in general. The
manuscript is very well written with a logical scientific flow and adds to the understanding of
NFLD globally. Minor revisions need to be done to further improve the manuscript.
1. Table 1 is too crowded. The authors should consider presenting only relevant data (those
which appeared significant and those required for discussion).
2. In the discussion the authors raised a very important point regarding urbanization and the
prevalence of NFLD. They however did not discuss their findings on urban rural differences in
the prevalence of NFLD. Adding this in the discussion will add more value to their findings and
generally improve the manuscript.
assistant