Reviewer's report
Title:Successful Management of Severe Intrahepatic Cholestasis of Pregnancy:
Report of a First Japanese Case
Version:3Date:19 August 2014
Reviewer: Giammarco Fava
Reviewer's report:
This paper by Kamimura et al. describes accurately a clinical case of severe
intrahepatic cholestasis in a Japanese pregnant woman. This case was
successfully treated with ursodeoxycholic acid and the genetic sequence
analysis has supported the diagnosis. The novelty of the manuscript is that such
disease is rare in Asian women. The paper is well written and easy to follow. The
Reviewer has only a concern to address.
Minor Essential Revisions
Page 9, line 17. The Authors should explain why they didn’t utilize MRI in the
pregnant woman.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: Yes, and I have assessed the statistics in my report.
Declaration of competing interests:
I declare that I have no competing interests
Reviewer's report
Title:Successful Management of Severe Intrahepatic Cholestasis of Pregnancy:
Report of a First Japanese Case
Version:3Date:19 August 2014
Reviewer: Giammarco Fava
Reviewer's report:
This paper by Kamimura et al. describes accurately a clinical case of severe
intrahepatic cholestasis in a Japanese pregnant woman. This case was
successfully treated with ursodeoxycholic acid and the genetic sequence
analysis has supported the diagnosis. The novelty of the manuscript is that such
disease is rare in Asian women. The paper is well written and easy to follow. The
Reviewer has only a concern to address.
Minor Essential Revisions
Page 9, line 17. The Authors should explain why they didn’t utilize MRI in the
pregnant woman.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: Yes, and I have assessed the statistics in my report.
Declaration of competing interests:
I declare that I have no competing interests
Please review this paper.
user
Reviewer's report
Title:Successful Management of Severe Intrahepatic Cholestasis of Pregnancy:
Report of a First Japanese Case
Version:3Date:19 August 2014
Reviewer: Giammarco Fava
Reviewer's report:
This paper by Kamimura et al. describes accurately a clinical case of severe
intrahepatic cholestasis in a Japanese pregnant woman. This case was
successfully treated with ursodeoxycholic acid and the genetic sequence
analysis has supported the diagnosis. The novelty of the manuscript is that such
disease is rare in Asian women. The paper is well written and easy to follow. The
Reviewer has only a concern to address.
Minor Essential Revisions
Page 9, line 17. The Authors should explain why they didn’t utilize MRI in the
pregnant woman.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: Yes, and I have assessed the statistics in my report.
Declaration of competing interests:
I declare that I have no competing interests
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