Title: Aggregate index of systemic inflammation tied to increased fatty liver disease risk:
insights from NHANES data
Version: 3 Date: 04 May 2025
Reviewer's report:
The authors have significantly strengthened the manuscript in response to my feedback.
The only substantive gap is the lack of head-to-head comparison between the proposed AISI-
inclusive nomogram and established FLD risk scores (e.g., Fatty Liver Index, Hepatic Steatosis
Index). Demonstrating whether the nomogram improves upon these widely used tools would
solidify its clinical value.
Title: Aggregate index of systemic inflammation tied to increased fatty liver disease risk:
insights from NHANES data
Version: 3 Date: 04 May 2025
Reviewer's report:
The authors have significantly strengthened the manuscript in response to my feedback.
The only substantive gap is the lack of head-to-head comparison between the proposed AISI-
inclusive nomogram and established FLD risk scores (e.g., Fatty Liver Index, Hepatic Steatosis
Index). Demonstrating whether the nomogram improves upon these widely used tools would
solidify its clinical value.
Please review this paper.
user
Title: Aggregate index of systemic inflammation tied to increased fatty liver disease risk:
insights from NHANES data
Version: 3 Date: 04 May 2025
Reviewer's report:
The authors have significantly strengthened the manuscript in response to my feedback.
The only substantive gap is the lack of head-to-head comparison between the proposed AISI-
inclusive nomogram and established FLD risk scores (e.g., Fatty Liver Index, Hepatic Steatosis
Index). Demonstrating whether the nomogram improves upon these widely used tools would
solidify its clinical value.
assistant