Title: Construction of disulfidptosis-related lncRNA signature for predicting the prognosis and
immune escape in colon adenocarcinoma
Version: 0 Date: 28 Sep 2023
Reviewer's report:
1. 3.1. Patient data are downloaded from the TCGA database for analysis, and the number of
tumor tissues and normal tissues included should be supplemented.
2. Table 1. In the materials and methods section, 476 tumor tissues were included in the analysis,
while only 447 tumor tissues were included in the Table 1. Please explain why the number of
tissues is different.
3. Authors should present DRLs in tabular format.
4.Table 1. 11/447#2.46%; 3/224#1.34%; 8/223#3.59%. Please explain why 11/447#2.47%;
3/224#1.35%; 8/223#3.58%.
5. Table 1. In TEST, T1+T2+T3+T4=99.99%. It is suggested that authors confirm the accuracy
of the data.
6. Table 1. In TEST, M0+M1+unknow=99.99%. It is recommended that authors double-check
the data for accuracy.
7.Figure 3E. Describe the meaning of Pr in the photo note.
8. Materials and Methods. Authors should provide details of the reagent used, including brand,
serial Number , and country.
9. There are some problems with the writing, please check the full text carefully. As shown in
Figure5, "Identification of the expression level of DRLs in colon cancer cell line." should be
changed to "Identification of the expression level of DRLs in colon cancer cell lines.”
10. The images in the whole text are consistent, and the manuscript is extremely readable.
The combination of bioinformatics analysis and simple verification ensures the accuracy of the
results.
Title: Construction of disulfidptosis-related lncRNA signature for predicting the prognosis and
immune escape in colon adenocarcinoma
Version: 0 Date: 28 Sep 2023
Reviewer's report:
1. 3.1. Patient data are downloaded from the TCGA database for analysis, and the number of
tumor tissues and normal tissues included should be supplemented.
2. Table 1. In the materials and methods section, 476 tumor tissues were included in the analysis,
while only 447 tumor tissues were included in the Table 1. Please explain why the number of
tissues is different.
3. Authors should present DRLs in tabular format.
4.Table 1. 11/447#2.46%; 3/224#1.34%; 8/223#3.59%. Please explain why 11/447#2.47%;
3/224#1.35%; 8/223#3.58%.
5. Table 1. In TEST, T1+T2+T3+T4=99.99%. It is suggested that authors confirm the accuracy
of the data.
6. Table 1. In TEST, M0+M1+unknow=99.99%. It is recommended that authors double-check
the data for accuracy.
7.Figure 3E. Describe the meaning of Pr in the photo note.
8. Materials and Methods. Authors should provide details of the reagent used, including brand,
serial Number , and country.
9. There are some problems with the writing, please check the full text carefully. As shown in
Figure5, "Identification of the expression level of DRLs in colon cancer cell line." should be
changed to "Identification of the expression level of DRLs in colon cancer cell lines.”
10. The images in the whole text are consistent, and the manuscript is extremely readable.
The combination of bioinformatics analysis and simple verification ensures the accuracy of the
results.
Please review this paper.
user
Title: Construction of disulfidptosis-related lncRNA signature for predicting the prognosis and
immune escape in colon adenocarcinoma
Version: 0 Date: 28 Sep 2023
Reviewer's report:
1. 3.1. Patient data are downloaded from the TCGA database for analysis, and the number of
tumor tissues and normal tissues included should be supplemented.
2. Table 1. In the materials and methods section, 476 tumor tissues were included in the analysis,
while only 447 tumor tissues were included in the Table 1. Please explain why the number of
tissues is different.
3. Authors should present DRLs in tabular format.
4.Table 1. 11/447#2.46%; 3/224#1.34%; 8/223#3.59%. Please explain why 11/447#2.47%;
3/224#1.35%; 8/223#3.58%.
5. Table 1. In TEST, T1+T2+T3+T4=99.99%. It is suggested that authors confirm the accuracy
of the data.
6. Table 1. In TEST, M0+M1+unknow=99.99%. It is recommended that authors double-check
the data for accuracy.
7.Figure 3E. Describe the meaning of Pr in the photo note.
8. Materials and Methods. Authors should provide details of the reagent used, including brand,
serial Number , and country.
9. There are some problems with the writing, please check the full text carefully. As shown in
Figure5, "Identification of the expression level of DRLs in colon cancer cell line." should be
changed to "Identification of the expression level of DRLs in colon cancer cell lines.”
10. The images in the whole text are consistent, and the manuscript is extremely readable.
The combination of bioinformatics analysis and simple verification ensures the accuracy of the
results.
assistant