Title: Predictors of pathological complete response after total neoadjuvant treatment using short
course radiotherapy for locally advanced rectal cancer
Version: 2 Date: 02 Feb 2025
Reviewer's report:
I appreciate the opportunity to review this manuscript. I should mention that I did not have the
chance to review the original manuscript. The manuscript in its current form is well written. I
reviewed both the reviewers' comments as well as the authors' comments and it seems to me
that the authors provided good responses. I will empashize that the authors mention that they
do not practice W&W regimen due to scarce evidence. My personal experience is that W&W is
currently being practiced in leading centers around the world. I think that the main flaw of this
manuscript is not being novel enough, especially due to a low number of patients. I recommend
the authors submit it to a local/regional journal.
Title: Predictors of pathological complete response after total neoadjuvant treatment using short
course radiotherapy for locally advanced rectal cancer
Version: 2 Date: 02 Feb 2025
Reviewer's report:
I appreciate the opportunity to review this manuscript. I should mention that I did not have the
chance to review the original manuscript. The manuscript in its current form is well written. I
reviewed both the reviewers' comments as well as the authors' comments and it seems to me
that the authors provided good responses. I will empashize that the authors mention that they
do not practice W&W regimen due to scarce evidence. My personal experience is that W&W is
currently being practiced in leading centers around the world. I think that the main flaw of this
manuscript is not being novel enough, especially due to a low number of patients. I recommend
the authors submit it to a local/regional journal.
Please review this paper.
user
Title: Predictors of pathological complete response after total neoadjuvant treatment using short
course radiotherapy for locally advanced rectal cancer
Version: 2 Date: 02 Feb 2025
Reviewer's report:
I appreciate the opportunity to review this manuscript. I should mention that I did not have the
chance to review the original manuscript. The manuscript in its current form is well written. I
reviewed both the reviewers' comments as well as the authors' comments and it seems to me
that the authors provided good responses. I will empashize that the authors mention that they
do not practice W&W regimen due to scarce evidence. My personal experience is that W&W is
currently being practiced in leading centers around the world. I think that the main flaw of this
manuscript is not being novel enough, especially due to a low number of patients. I recommend
the authors submit it to a local/regional journal.
assistant