Title: Impact of cone-beam computed tomography with automated feeder detection software
on the survival outcome of patients with hepatocellular carcinoma during treatment with
conventional transarterial chemoembolization
Version: 1 Date: 21 Oct 2021
Reviewer's report:
Authors should be commended for their work.
I have the following comments:
1) Usually the main limitation of CT scan after conventional TACE is that it cannot capture
eventual residual viable tumoral areas in the nodule (due to lipiodol stain). How this new
technique overcomes this issue?
2) THe Kaplan Meyer curve should be improved reporting censored and number at risk.
3) Overall survival in HCC patients could be due to other clinical factors that should be
mentioned in the paper. Comment at least these, citing the relevant papers:
- Diabetes (PMID: 23845075)
- Use of eventual post-treatment systemic therapies (for example sorafenib or regorafenib,
PMID: 31877664, or newer immunotherapy ,PMID: 33086471).
Title: Impact of cone-beam computed tomography with automated feeder detection software
on the survival outcome of patients with hepatocellular carcinoma during treatment with
conventional transarterial chemoembolization
Version: 1 Date: 21 Oct 2021
Reviewer's report:
Authors should be commended for their work.
I have the following comments:
1) Usually the main limitation of CT scan after conventional TACE is that it cannot capture
eventual residual viable tumoral areas in the nodule (due to lipiodol stain). How this new
technique overcomes this issue?
2) THe Kaplan Meyer curve should be improved reporting censored and number at risk.
3) Overall survival in HCC patients could be due to other clinical factors that should be
mentioned in the paper. Comment at least these, citing the relevant papers:
- Diabetes (PMID: 23845075)
- Use of eventual post-treatment systemic therapies (for example sorafenib or regorafenib,
PMID: 31877664, or newer immunotherapy ,PMID: 33086471).
Please review this paper.
user
Title: Impact of cone-beam computed tomography with automated feeder detection software
on the survival outcome of patients with hepatocellular carcinoma during treatment with
conventional transarterial chemoembolization
Version: 1 Date: 21 Oct 2021
Reviewer's report:
Authors should be commended for their work.
I have the following comments:
1) Usually the main limitation of CT scan after conventional TACE is that it cannot capture
eventual residual viable tumoral areas in the nodule (due to lipiodol stain). How this new
technique overcomes this issue?
2) THe Kaplan Meyer curve should be improved reporting censored and number at risk.
3) Overall survival in HCC patients could be due to other clinical factors that should be
mentioned in the paper. Comment at least these, citing the relevant papers:
- Diabetes (PMID: 23845075)
- Use of eventual post-treatment systemic therapies (for example sorafenib or regorafenib,
PMID: 31877664, or newer immunotherapy ,PMID: 33086471).
assistant