Title: Pathological complete response after conversion therapy in unresectable hepatocellular
carcinoma: A retrospective study
Version: 0 Date: 28 Dec 2023
Reviewer's report:
the paper by Jia et al is a paper on an intersting focus.
Radiological and confirmed pathologycal response rate after the conversion therapy for HCC
could be intersting for future real word approch and studies are laking.
the main focus is on result and statistical analysis:
However, starting from the data the first thing that seems to be strage is the classification of
patients with BCLC: 51.7 % in stage 0-A, 8.3%in B and 40% in C; but PVTT was present in
75%. This seems to be quite strange because in the correct definition of BCLC stage portal
invasion authomatically defined a BCLC of stage C. how is it possibile?
Data on liver function are totally absent, these data are necessary
COx regression analysis and factors that can influence the outcome are lacking
data on death causes are absent.
this information are necessary to better understend the data presented
Title: Pathological complete response after conversion therapy in unresectable hepatocellular
carcinoma: A retrospective study
Version: 0 Date: 28 Dec 2023
Reviewer's report:
the paper by Jia et al is a paper on an intersting focus.
Radiological and confirmed pathologycal response rate after the conversion therapy for HCC
could be intersting for future real word approch and studies are laking.
the main focus is on result and statistical analysis:
However, starting from the data the first thing that seems to be strage is the classification of
patients with BCLC: 51.7 % in stage 0-A, 8.3%in B and 40% in C; but PVTT was present in
75%. This seems to be quite strange because in the correct definition of BCLC stage portal
invasion authomatically defined a BCLC of stage C. how is it possibile?
Data on liver function are totally absent, these data are necessary
COx regression analysis and factors that can influence the outcome are lacking
data on death causes are absent.
this information are necessary to better understend the data presented
Please review this paper.
user
Title: Pathological complete response after conversion therapy in unresectable hepatocellular
carcinoma: A retrospective study
Version: 0 Date: 28 Dec 2023
Reviewer's report:
the paper by Jia et al is a paper on an intersting focus.
Radiological and confirmed pathologycal response rate after the conversion therapy for HCC
could be intersting for future real word approch and studies are laking.
the main focus is on result and statistical analysis:
However, starting from the data the first thing that seems to be strage is the classification of
patients with BCLC: 51.7 % in stage 0-A, 8.3%in B and 40% in C; but PVTT was present in
75%. This seems to be quite strange because in the correct definition of BCLC stage portal
invasion authomatically defined a BCLC of stage C. how is it possibile?
Data on liver function are totally absent, these data are necessary
COx regression analysis and factors that can influence the outcome are lacking
data on death causes are absent.
this information are necessary to better understend the data presented
assistant