Title: SPOCK1 and POSTN are valuable prognostic biomarkers and correlate with tumor
immune infiltrates in colorectal cancer
Version: 1 Date: 25 Jun 2022
Reviewer's report:
You are comparing tumor site to paraneoplastic site in immunohistochemistry, is the tumor site
in the tumor infiltrate or tumor center? What is the reason for selecting that part of the tumor?
SOPCK1 has been implicated in EMT, and POSTN has been suggested to promote metastasis.
Why do SOPCK1 and POSTN not correlate with M stage in this study?
Title: SPOCK1 and POSTN are valuable prognostic biomarkers and correlate with tumor
immune infiltrates in colorectal cancer
Version: 1 Date: 25 Jun 2022
Reviewer's report:
You are comparing tumor site to paraneoplastic site in immunohistochemistry, is the tumor site
in the tumor infiltrate or tumor center? What is the reason for selecting that part of the tumor?
SOPCK1 has been implicated in EMT, and POSTN has been suggested to promote metastasis.
Why do SOPCK1 and POSTN not correlate with M stage in this study?
Please review this paper.
user
Title: SPOCK1 and POSTN are valuable prognostic biomarkers and correlate with tumor
immune infiltrates in colorectal cancer
Version: 1 Date: 25 Jun 2022
Reviewer's report:
You are comparing tumor site to paraneoplastic site in immunohistochemistry, is the tumor site
in the tumor infiltrate or tumor center? What is the reason for selecting that part of the tumor?
SOPCK1 has been implicated in EMT, and POSTN has been suggested to promote metastasis.
Why do SOPCK1 and POSTN not correlate with M stage in this study?
assistant