Title: Effect of Wet-heparinized Suction on The Quality of Mediastinal Solid Tumor Specimens
obtained by Endoscopic Ultrasound-guided Fine-needle Aspiration: a retrospective study from
a single center
Version: 2 Date: 03 May 2023
Reviewer's report:
I would like to congratulate the authors for reporting their novel method with Wet-heparinized
Suction on The Quality of Mediastinal Solid Tumor Specimens obtained by Endoscopic
Ultrasound-guided Fine-needle Aspiration. But I still have two questions for the authors to
answer.
1. In previous reports, wet picture technique can reduce the red blood cell contamination, but
the authors reported no significant difference between the two groups, why?
2. The authors reported that Wet-heparinized Suction can improve specimen quality compared
with traditional puncture techniques, but there is no clinical difference in diagnostic sensitivity
and specificity in the report. So what is the practical clinical significance of this method?
Title: Effect of Wet-heparinized Suction on The Quality of Mediastinal Solid Tumor Specimens
obtained by Endoscopic Ultrasound-guided Fine-needle Aspiration: a retrospective study from
a single center
Version: 2 Date: 03 May 2023
Reviewer's report:
I would like to congratulate the authors for reporting their novel method with Wet-heparinized
Suction on The Quality of Mediastinal Solid Tumor Specimens obtained by Endoscopic
Ultrasound-guided Fine-needle Aspiration. But I still have two questions for the authors to
answer.
1. In previous reports, wet picture technique can reduce the red blood cell contamination, but
the authors reported no significant difference between the two groups, why?
2. The authors reported that Wet-heparinized Suction can improve specimen quality compared
with traditional puncture techniques, but there is no clinical difference in diagnostic sensitivity
and specificity in the report. So what is the practical clinical significance of this method?
Please review this paper.
user
Title: Effect of Wet-heparinized Suction on The Quality of Mediastinal Solid Tumor Specimens
obtained by Endoscopic Ultrasound-guided Fine-needle Aspiration: a retrospective study from
a single center
Version: 2 Date: 03 May 2023
Reviewer's report:
I would like to congratulate the authors for reporting their novel method with Wet-heparinized
Suction on The Quality of Mediastinal Solid Tumor Specimens obtained by Endoscopic
Ultrasound-guided Fine-needle Aspiration. But I still have two questions for the authors to
answer.
1. In previous reports, wet picture technique can reduce the red blood cell contamination, but
the authors reported no significant difference between the two groups, why?
2. The authors reported that Wet-heparinized Suction can improve specimen quality compared
with traditional puncture techniques, but there is no clinical difference in diagnostic sensitivity
and specificity in the report. So what is the practical clinical significance of this method?
assistant