Title: Analysis of clinical features and prognostic factors in patients with Hepatic Hydrothorax:
A single-center study from China
Version: 1 Date: 04 May 2022
Reviewer:  Sikandar Ansari
Reviewer's report:
1-page 5 last line:
All patients had pleural fluid combined with ascites, including 87 cases (66.4%) with massive
pleural fluid combined with massive ascites and 96 cases (73.3%) with compressive pulmonary
atelectasis.
Recommendation: This line is not clear and may need to be rephrased.
2-page 5 line 4:This was followed by hyponatraemia in 52 cases (39.7%), infection of the pleural
fluid in 30 cases (22.9%), renal insufficiency in 24 cases (18.3%), liver failure in 21 cases (16%),
peritonitis in 18 cases (13.7%), hepatic encephalopathy and gastrointestinal bleeding both in 16
cases (12.2%) and hepatorenal syndrome in 9 cases
Recommendation : Please consider mentioning how pleural fluid infection was determined? by
culture? by Empyema standards?
3-Page 8:The most common symptoms of HH are dyspnoea and abdominal distention, which
may be associated with massive pleural effusion compressing the lung tissue and massive
accumulation of abdominal fluid resulting in.
Recommendation: Spelling of Dyspnea needs to be corrected.
4: Page 8:More complete clinical data from hospital records of patients with decompensated
cirrhosis and ascites admitted to the First Hospital of Jilin University from January 2013 to June
2021 were extracted for retrospective analysis, and risk factors affecting prognostic survival
were further analysed based on follow-up survival time.
Recommendation: Spelling of analyzed needs to be corrected.
5: spelling for Hyponatremia needs to be corrected at multiple sites.
Title: Analysis of clinical features and prognostic factors in patients with Hepatic Hydrothorax:
A single-center study from China
Version: 1 Date: 04 May 2022
Reviewer:  Sikandar Ansari
Reviewer's report:
1-page 5 last line:
All patients had pleural fluid combined with ascites, including 87 cases (66.4%) with massive
pleural fluid combined with massive ascites and 96 cases (73.3%) with compressive pulmonary
atelectasis.
Recommendation: This line is not clear and may need to be rephrased.
2-page 5 line 4:This was followed by hyponatraemia in 52 cases (39.7%), infection of the pleural
fluid in 30 cases (22.9%), renal insufficiency in 24 cases (18.3%), liver failure in 21 cases (16%),
peritonitis in 18 cases (13.7%), hepatic encephalopathy and gastrointestinal bleeding both in 16
cases (12.2%) and hepatorenal syndrome in 9 cases
Recommendation : Please consider mentioning how pleural fluid infection was determined? by
culture? by Empyema standards?
3-Page 8:The most common symptoms of HH are dyspnoea and abdominal distention, which
may be associated with massive pleural effusion compressing the lung tissue and massive
accumulation of abdominal fluid resulting in.
Recommendation: Spelling of Dyspnea needs to be corrected.
4: Page 8:More complete clinical data from hospital records of patients with decompensated
cirrhosis and ascites admitted to the First Hospital of Jilin University from January 2013 to June
2021 were extracted for retrospective analysis, and risk factors affecting prognostic survival
were further analysed based on follow-up survival time.
Recommendation: Spelling of analyzed needs to be corrected.
5: spelling for Hyponatremia needs to be corrected at multiple sites.
Please review this paper.
user
Title: Analysis of clinical features and prognostic factors in patients with Hepatic Hydrothorax:
A single-center study from China
Version: 1 Date: 04 May 2022
Reviewer:  Sikandar Ansari
Reviewer's report:
1-page 5 last line:
All patients had pleural fluid combined with ascites, including 87 cases (66.4%) with massive
pleural fluid combined with massive ascites and 96 cases (73.3%) with compressive pulmonary
atelectasis.
Recommendation: This line is not clear and may need to be rephrased.
2-page 5 line 4:This was followed by hyponatraemia in 52 cases (39.7%), infection of the pleural
fluid in 30 cases (22.9%), renal insufficiency in 24 cases (18.3%), liver failure in 21 cases (16%),
peritonitis in 18 cases (13.7%), hepatic encephalopathy and gastrointestinal bleeding both in 16
cases (12.2%) and hepatorenal syndrome in 9 cases
Recommendation : Please consider mentioning how pleural fluid infection was determined? by
culture? by Empyema standards?
3-Page 8:The most common symptoms of HH are dyspnoea and abdominal distention, which
may be associated with massive pleural effusion compressing the lung tissue and massive
accumulation of abdominal fluid resulting in.
Recommendation: Spelling of Dyspnea needs to be corrected.
4: Page 8:More complete clinical data from hospital records of patients with decompensated
cirrhosis and ascites admitted to the First Hospital of Jilin University from January 2013 to June
2021 were extracted for retrospective analysis, and risk factors affecting prognostic survival
were further analysed based on follow-up survival time.
Recommendation: Spelling of analyzed needs to be corrected.
5: spelling for Hyponatremia needs to be corrected at multiple sites.
assistant