Title: Gut microbiome alterations in colitis rats after moxibustion at bilateral Tianshu acupoints
Version: 2 Date: 07 Dec 2021
Reviewer's report:
1. Changes have not been  marked in the revised manuscript.
2. The DAI score, colon tissues pathological section and histology score of five groups  are very
important.  This revised version supplements these results, but does not answer the reason why
the first manuscript is not showed.
3. The authors answered that it is well known that the application of acute model will change the
intestinal flora, but did not explain whether this model can reflect the characteristics of intestinal
flora of chronic ulcerative colitis.
Title: Gut microbiome alterations in colitis rats after moxibustion at bilateral Tianshu acupoints
Version: 2 Date: 07 Dec 2021
Reviewer's report:
1. Changes have not been  marked in the revised manuscript.
2. The DAI score, colon tissues pathological section and histology score of five groups  are very
important.  This revised version supplements these results, but does not answer the reason why
the first manuscript is not showed.
3. The authors answered that it is well known that the application of acute model will change the
intestinal flora, but did not explain whether this model can reflect the characteristics of intestinal
flora of chronic ulcerative colitis.
Please review this paper.
user
Title: Gut microbiome alterations in colitis rats after moxibustion at bilateral Tianshu acupoints
Version: 2 Date: 07 Dec 2021
Reviewer's report:
1. Changes have not been  marked in the revised manuscript.
2. The DAI score, colon tissues pathological section and histology score of five groups  are very
important.  This revised version supplements these results, but does not answer the reason why
the first manuscript is not showed.
3. The authors answered that it is well known that the application of acute model will change the
intestinal flora, but did not explain whether this model can reflect the characteristics of intestinal
flora of chronic ulcerative colitis.
assistant