Title: Management of post-operative pancreatic fistulas following Longmire-Traverso pylorus-
preserving pancreatoduodenectomy by endoscopic vacuum-assisted closure therapy
Version: 2 Date: 13 Sep 2021
Reviewer:  Antonino Granata
Reviewer's report:
The manuscript is well written and built. The data are well collected and described.
In my opinion the proposed handmade device can be very hazardous in clinical practice even in
skilled hands. at the best of my knowledge, are available on the market dedicated devices with
“CE” mark, why did the authors decide to use a handmade device?
Vacuum therapy can be helpful in treatment in upper- GI fistula even pancreatic, but in
my opinion, the authors should compare with other well-established techniques available in
literature to exalt the proposed data.
I’s a very small court of patient this is a major limitation of the study.
Please explain the issues about the exitus of the "patient 8"
Title: Management of post-operative pancreatic fistulas following Longmire-Traverso pylorus-
preserving pancreatoduodenectomy by endoscopic vacuum-assisted closure therapy
Version: 2 Date: 13 Sep 2021
Reviewer:  Antonino Granata
Reviewer's report:
The manuscript is well written and built. The data are well collected and described.
In my opinion the proposed handmade device can be very hazardous in clinical practice even in
skilled hands. at the best of my knowledge, are available on the market dedicated devices with
“CE” mark, why did the authors decide to use a handmade device?
Vacuum therapy can be helpful in treatment in upper- GI fistula even pancreatic, but in
my opinion, the authors should compare with other well-established techniques available in
literature to exalt the proposed data.
I’s a very small court of patient this is a major limitation of the study.
Please explain the issues about the exitus of the "patient 8"
Please review this paper.
user
Title: Management of post-operative pancreatic fistulas following Longmire-Traverso pylorus-
preserving pancreatoduodenectomy by endoscopic vacuum-assisted closure therapy
Version: 2 Date: 13 Sep 2021
Reviewer:  Antonino Granata
Reviewer's report:
The manuscript is well written and built. The data are well collected and described.
In my opinion the proposed handmade device can be very hazardous in clinical practice even in
skilled hands. at the best of my knowledge, are available on the market dedicated devices with
“CE” mark, why did the authors decide to use a handmade device?
Vacuum therapy can be helpful in treatment in upper- GI fistula even pancreatic, but in
my opinion, the authors should compare with other well-established techniques available in
literature to exalt the proposed data.
I’s a very small court of patient this is a major limitation of the study.
Please explain the issues about the exitus of the "patient 8"
assistant