Reviewer's report
Title:Imbalance of tissue inhibitors of metalloproteinases (TIMP) - 1 and - 4
serum levels, in patients with inflammatory bowel disease
Version: 2Date:20 June 2008
Reviewer: Klaus Fellermann
Reviewer's report:
As I stated in my first review I do not understand the significance of isolated
TIMP serum levels in IBD. In order to improve the manuscript I recommended
additional investigations, at leats MMP serum levels. However, this seems to be
impossible and my final conclusion is that I cannot accept this paper for
publication in its present form.
Level of interest: An article of limited interest
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests.
Reviewer's report
Title:Imbalance of tissue inhibitors of metalloproteinases (TIMP) - 1 and - 4
serum levels, in patients with inflammatory bowel disease
Version: 2Date:20 June 2008
Reviewer: Klaus Fellermann
Reviewer's report:
As I stated in my first review I do not understand the significance of isolated
TIMP serum levels in IBD. In order to improve the manuscript I recommended
additional investigations, at leats MMP serum levels. However, this seems to be
impossible and my final conclusion is that I cannot accept this paper for
publication in its present form.
Level of interest: An article of limited interest
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests.
Please review this paper.
user
Reviewer's report
Title:Imbalance of tissue inhibitors of metalloproteinases (TIMP) - 1 and - 4
serum levels, in patients with inflammatory bowel disease
Version: 2Date:20 June 2008
Reviewer: Klaus Fellermann
Reviewer's report:
As I stated in my first review I do not understand the significance of isolated
TIMP serum levels in IBD. In order to improve the manuscript I recommended
additional investigations, at leats MMP serum levels. However, this seems to be
impossible and my final conclusion is that I cannot accept this paper for
publication in its present form.
Level of interest: An article of limited interest
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests.
assistant