Title: B3GNT7 regulates mucin O-glycosylation to alleviate colonic inflammation
Version: 1 Date: 07 Dec 2023
Reviewer's report:
In this study, the authors investigate  the specific role of B3GNT7 in ulcerative colitis and
explore its potential as a molecular marker. The subject matter is highly relevant, and the results
present relevant findings. However, a few minor points require further clarification to enhance
the manuscript for publication.
1) The presence of minor grammatical errors in the text has been noted. To address this, I
recommend utilizing an online grammar checker or an English correction service for thorough
proofreading.
2) In the sentence, "Protein interaction analysis demonstrated stronger interaction between
B3GNT7 and the mucin MUC family, including Muc2, Muc3, and Muc6," from the section
titled "Functional enrichment analysis of B3GNT7," it is unclear how protein interactions were
evaluated from gene expression data. To improve clarity, it is necessary to provide a more
detailed explanation of this analysis, both in this section and in the Material and Methods section
Title: B3GNT7 regulates mucin O-glycosylation to alleviate colonic inflammation
Version: 1 Date: 07 Dec 2023
Reviewer's report:
In this study, the authors investigate  the specific role of B3GNT7 in ulcerative colitis and
explore its potential as a molecular marker. The subject matter is highly relevant, and the results
present relevant findings. However, a few minor points require further clarification to enhance
the manuscript for publication.
1) The presence of minor grammatical errors in the text has been noted. To address this, I
recommend utilizing an online grammar checker or an English correction service for thorough
proofreading.
2) In the sentence, "Protein interaction analysis demonstrated stronger interaction between
B3GNT7 and the mucin MUC family, including Muc2, Muc3, and Muc6," from the section
titled "Functional enrichment analysis of B3GNT7," it is unclear how protein interactions were
evaluated from gene expression data. To improve clarity, it is necessary to provide a more
detailed explanation of this analysis, both in this section and in the Material and Methods section
Please review this paper.
user
Title: B3GNT7 regulates mucin O-glycosylation to alleviate colonic inflammation
Version: 1 Date: 07 Dec 2023
Reviewer's report:
In this study, the authors investigate  the specific role of B3GNT7 in ulcerative colitis and
explore its potential as a molecular marker. The subject matter is highly relevant, and the results
present relevant findings. However, a few minor points require further clarification to enhance
the manuscript for publication.
1) The presence of minor grammatical errors in the text has been noted. To address this, I
recommend utilizing an online grammar checker or an English correction service for thorough
proofreading.
2) In the sentence, "Protein interaction analysis demonstrated stronger interaction between
B3GNT7 and the mucin MUC family, including Muc2, Muc3, and Muc6," from the section
titled "Functional enrichment analysis of B3GNT7," it is unclear how protein interactions were
evaluated from gene expression data. To improve clarity, it is necessary to provide a more
detailed explanation of this analysis, both in this section and in the Material and Methods section
assistant