Title: Risk factors for metachronous colorectal cancer and advanced neoplasia following
primary colorectal cancer: A systematic review and meta-analysis
Version: 0 Date: 05 Jul 2023
Reviewer's report:
In this article, Zhang explored the clinical, environmental and  and endoscopic risk factors of
metachronous CRC and advanced neoplasia. In general, the article is well written with sound
methodology. My only questions are:
1.Why the authors chose risk ratio, rather than odds ratio as the primary outcome with most
included studies being retrospective cohort?
2.How did the authors transplate different outcome measurem (HR, OR, and RR) in different
studies into common parameter for meta-analysis?
Title: Risk factors for metachronous colorectal cancer and advanced neoplasia following
primary colorectal cancer: A systematic review and meta-analysis
Version: 0 Date: 05 Jul 2023
Reviewer's report:
In this article, Zhang explored the clinical, environmental and  and endoscopic risk factors of
metachronous CRC and advanced neoplasia. In general, the article is well written with sound
methodology. My only questions are:
1.Why the authors chose risk ratio, rather than odds ratio as the primary outcome with most
included studies being retrospective cohort?
2.How did the authors transplate different outcome measurem (HR, OR, and RR) in different
studies into common parameter for meta-analysis?
Please review this paper.
user
Title: Risk factors for metachronous colorectal cancer and advanced neoplasia following
primary colorectal cancer: A systematic review and meta-analysis
Version: 0 Date: 05 Jul 2023
Reviewer's report:
In this article, Zhang explored the clinical, environmental and  and endoscopic risk factors of
metachronous CRC and advanced neoplasia. In general, the article is well written with sound
methodology. My only questions are:
1.Why the authors chose risk ratio, rather than odds ratio as the primary outcome with most
included studies being retrospective cohort?
2.How did the authors transplate different outcome measurem (HR, OR, and RR) in different
studies into common parameter for meta-analysis?
assistant