Title: Association of FIB-4 Index and Clinical Outcomes in Critically ill Patients with Acute
Kidney Injury: A Cohort Study
Version: 1 Date: 13 Oct 2021
Reviewer's report:
The analysis has been carried out considering the background that required intensive care, and
there is no objection to the research design and analysis method.
The concern is that the values of AST, ALT, and platelets, which are the components of the Fib4
Index, often fluctuate in cases with AKI and requiring intensive care.
Although the background factors have been adjusted, it is difficult to mention that the Fib4 Index
value directly reflects liver fibrosis at the time of admission to the intensive care unit.
The data at the time of entering the intensive care unit are being analyzed. If you can analyze the
data before entering the intensive care unit, you will be able to better examine the relationship
between the degree of liver fibrosis and the mortality rate of AKI patients who require intensive
care.
Title: Association of FIB-4 Index and Clinical Outcomes in Critically ill Patients with Acute
Kidney Injury: A Cohort Study
Version: 1 Date: 13 Oct 2021
Reviewer's report:
The analysis has been carried out considering the background that required intensive care, and
there is no objection to the research design and analysis method.
The concern is that the values of AST, ALT, and platelets, which are the components of the Fib4
Index, often fluctuate in cases with AKI and requiring intensive care.
Although the background factors have been adjusted, it is difficult to mention that the Fib4 Index
value directly reflects liver fibrosis at the time of admission to the intensive care unit.
The data at the time of entering the intensive care unit are being analyzed. If you can analyze the
data before entering the intensive care unit, you will be able to better examine the relationship
between the degree of liver fibrosis and the mortality rate of AKI patients who require intensive
care.
Please review this paper.
user
Title: Association of FIB-4 Index and Clinical Outcomes in Critically ill Patients with Acute
Kidney Injury: A Cohort Study
Version: 1 Date: 13 Oct 2021
Reviewer's report:
The analysis has been carried out considering the background that required intensive care, and
there is no objection to the research design and analysis method.
The concern is that the values of AST, ALT, and platelets, which are the components of the Fib4
Index, often fluctuate in cases with AKI and requiring intensive care.
Although the background factors have been adjusted, it is difficult to mention that the Fib4 Index
value directly reflects liver fibrosis at the time of admission to the intensive care unit.
The data at the time of entering the intensive care unit are being analyzed. If you can analyze the
data before entering the intensive care unit, you will be able to better examine the relationship
between the degree of liver fibrosis and the mortality rate of AKI patients who require intensive
care.
assistant