Title: Medication Use Among Patients with Crohn’s Disease or Ulcerative Colitis Before and
After the Initiation of Advanced Therapy
Version: 5 Date: 13 Nov 2022
Reviewer's report:
The authors adequately addressed the points of critique. They chose to analyze the influence
of modern treatment options on glucocorticoids as well as pain medication. The former having
been shown in plenty of other publications before this, the latter being very new.
There are only minor points of critique.
A) Considering, that patients might be taking analgetics for different reasons, the statistically
significant reduction in pain medication is quite remarkable and is worth mentioning in the
abstract.
B) Page 7, first sentence: "these medications [analgetics]" do not result in healing of the inflamed
intestine.
C) Page 14, Number of pain medication fills: The equations model did not show a significiant
change in pain medication fill rather than showing that there was no significant change.
Title: Medication Use Among Patients with Crohn’s Disease or Ulcerative Colitis Before and
After the Initiation of Advanced Therapy
Version: 5 Date: 13 Nov 2022
Reviewer's report:
The authors adequately addressed the points of critique. They chose to analyze the influence
of modern treatment options on glucocorticoids as well as pain medication. The former having
been shown in plenty of other publications before this, the latter being very new.
There are only minor points of critique.
A) Considering, that patients might be taking analgetics for different reasons, the statistically
significant reduction in pain medication is quite remarkable and is worth mentioning in the
abstract.
B) Page 7, first sentence: "these medications [analgetics]" do not result in healing of the inflamed
intestine.
C) Page 14, Number of pain medication fills: The equations model did not show a significiant
change in pain medication fill rather than showing that there was no significant change.
Please review this paper.
user
Title: Medication Use Among Patients with Crohn’s Disease or Ulcerative Colitis Before and
After the Initiation of Advanced Therapy
Version: 5 Date: 13 Nov 2022
Reviewer's report:
The authors adequately addressed the points of critique. They chose to analyze the influence
of modern treatment options on glucocorticoids as well as pain medication. The former having
been shown in plenty of other publications before this, the latter being very new.
There are only minor points of critique.
A) Considering, that patients might be taking analgetics for different reasons, the statistically
significant reduction in pain medication is quite remarkable and is worth mentioning in the
abstract.
B) Page 7, first sentence: "these medications [analgetics]" do not result in healing of the inflamed
intestine.
C) Page 14, Number of pain medication fills: The equations model did not show a significiant
change in pain medication fill rather than showing that there was no significant change.
assistant