Reviewer ’s report  
 
Title: Two cases of agenesis of the dorsal pancreas and a review of the literature  
 
Version: 0 Date: 04 Feb 2020  
 
Reviewer: Yoshiaki Kawaguchi  
 
Reviewer's report:  
 
This paper is mentioned about cases of agenesis of the dorsal pancreas (ADP). ADP is a very 
rare anatomical variation of the pancreas, which almost has been discovered by chance on CT or 
MRI images. I think that this paper is very interesting because it is  important to know and 
understand this disease. But there are some points to be modified or added for paper.  
 
1. Are there case reports of ADP, which may cause recurrent pancreatitis? In the cases how 
are the patients treated? For example, if the patients have pancreatic duct hypertention, 
endoscopic sphincterotomy may be effective.  
2. It is important to differentiate ADP from pancreatic fat infiltration or chronic pancreatitis. 
How can the author perform the differentiation?  
3. In case of ADP, is there min or papilla?  
4. Is agenesis of the ventral pancreas reported? If reported, the author add it into this paper.  
 
 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
Yes 
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
Yes 
 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in t he manus cript or would you recommend an 
additional statistical review?  
If an additional statistical review is recommended, please speci fy what aspects require further 
assessment in your comments to the editors.  
 
Not relevant to this manuscript  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Not suitable for publication unless extensively edited  
 
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following que stions:  
 
1. Have you in the past five years received reimbursements, f ees, funding, or salary from an 
organisation that may in any way gain or lose financial ly from the publication of this 
manuscript, either now or in the future?  
 
2. Do you hold any stocks o r shares in an organisation t hat may in any way gain or lose 
financially from the publication of this manuscript, either now or in the future?  
 
3. Do you hold or are you currently applying for any patents  relating to the content of the 
manuscript?  
 
4. Have y ou received reimbursements, fees, funding, or salary from an organization that 
holds or has applied for patents relating to the content of the manuscript?  
 
5. Do you have any other financial competing interests?  
 
6. Do you have any non -financial competing in terests in relation to this paper?  
 
If you can answer no to all of the above, write 'I declare that I have  no competi ng interests' 
below. If your reply is yes to any, please give details below.  
 
I declare that I have no  competing interests  
 
I agree to the open peer review policy of the journal. I understan d that my name will be included 
on my report to the authors and, if the manuscript is accepted for publication, my named report  
including any attachments I upload will be posted on the websi te along with the authors' 
responses. I agree for my report to be made available under an Open Access Creative Commons  
CC-BY license ( http://creativecommons.org/licenses/by/4.0/ ). I understand that any comments 
which I do not wish to be included in my name d report can be in cluded as confidential comments 
to the editors, which will not be published.  
 
I agree to the open peer review policy of the journal  
Reviewer ’s report  
 
Title: Two cases of agenesis of the dorsal pancreas and a review of the literature  
 
Version: 0 Date: 04 Feb 2020  
 
Reviewer: Yoshiaki Kawaguchi  
 
Reviewer's report:  
 
This paper is mentioned about cases of agenesis of the dorsal pancreas (ADP). ADP is a very 
rare anatomical variation of the pancreas, which almost has been discovered by chance on CT or 
MRI images. I think that this paper is very interesting because it is  important to know and 
understand this disease. But there are some points to be modified or added for paper.  
 
1. Are there case reports of ADP, which may cause recurrent pancreatitis? In the cases how 
are the patients treated? For example, if the patients have pancreatic duct hypertention, 
endoscopic sphincterotomy may be effective.  
2. It is important to differentiate ADP from pancreatic fat infiltration or chronic pancreatitis. 
How can the author perform the differentiation?  
3. In case of ADP, is there min or papilla?  
4. Is agenesis of the ventral pancreas reported? If reported, the author add it into this paper.  
 
 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
Yes 
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
Yes 
 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in t he manus cript or would you recommend an 
additional statistical review?  
If an additional statistical review is recommended, please speci fy what aspects require further 
assessment in your comments to the editors.  
 
Not relevant to this manuscript  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Not suitable for publication unless extensively edited  
 
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following que stions:  
 
1. Have you in the past five years received reimbursements, f ees, funding, or salary from an 
organisation that may in any way gain or lose financial ly from the publication of this 
manuscript, either now or in the future?  
 
2. Do you hold any stocks o r shares in an organisation t hat may in any way gain or lose 
financially from the publication of this manuscript, either now or in the future?  
 
3. Do you hold or are you currently applying for any patents  relating to the content of the 
manuscript?  
 
4. Have y ou received reimbursements, fees, funding, or salary from an organization that 
holds or has applied for patents relating to the content of the manuscript?  
 
5. Do you have any other financial competing interests?  
 
6. Do you have any non -financial competing in terests in relation to this paper?  
 
If you can answer no to all of the above, write 'I declare that I have  no competi ng interests' 
below. If your reply is yes to any, please give details below.  
 
I declare that I have no  competing interests  
 
I agree to the open peer review policy of the journal. I understan d that my name will be included 
on my report to the authors and, if the manuscript is accepted for publication, my named report  
including any attachments I upload will be posted on the websi te along with the authors' 
responses. I agree for my report to be made available under an Open Access Creative Commons  
CC-BY license ( http://creativecommons.org/licenses/by/4.0/ ). I understand that any comments 
which I do not wish to be included in my name d report can be in cluded as confidential comments 
to the editors, which will not be published.  
 
I agree to the open peer review policy of the journal  
Please review this paper.
user
Reviewer ’s report  
 
Title: Two cases of agenesis of the dorsal pancreas and a review of the literature  
 
Version: 0 Date: 04 Feb 2020  
 
Reviewer: Yoshiaki Kawaguchi  
 
Reviewer's report:  
 
This paper is mentioned about cases of agenesis of the dorsal pancreas (ADP). ADP is a very 
rare anatomical variation of the pancreas, which almost has been discovered by chance on CT or 
MRI images. I think that this paper is very interesting because it is  important to know and 
understand this disease. But there are some points to be modified or added for paper.  
 
1. Are there case reports of ADP, which may cause recurrent pancreatitis? In the cases how 
are the patients treated? For example, if the patients have pancreatic duct hypertention, 
endoscopic sphincterotomy may be effective.  
2. It is important to differentiate ADP from pancreatic fat infiltration or chronic pancreatitis. 
How can the author perform the differentiation?  
3. In case of ADP, is there min or papilla?  
4. Is agenesis of the ventral pancreas reported? If reported, the author add it into this paper.  
 
 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
Yes 
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
Yes 
 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in t he manus cript or would you recommend an 
additional statistical review?  
If an additional statistical review is recommended, please speci fy what aspects require further 
assessment in your comments to the editors.  
 
Not relevant to this manuscript  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Not suitable for publication unless extensively edited  
 
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following que stions:  
 
1. Have you in the past five years received reimbursements, f ees, funding, or salary from an 
organisation that may in any way gain or lose financial ly from the publication of this 
manuscript, either now or in the future?  
 
2. Do you hold any stocks o r shares in an organisation t hat may in any way gain or lose 
financially from the publication of this manuscript, either now or in the future?  
 
3. Do you hold or are you currently applying for any patents  relating to the content of the 
manuscript?  
 
4. Have y ou received reimbursements, fees, funding, or salary from an organization that 
holds or has applied for patents relating to the content of the manuscript?  
 
5. Do you have any other financial competing interests?  
 
6. Do you have any non -financial competing in terests in relation to this paper?  
 
If you can answer no to all of the above, write 'I declare that I have  no competi ng interests' 
below. If your reply is yes to any, please give details below.  
 
I declare that I have no  competing interests  
 
I agree to the open peer review policy of the journal. I understan d that my name will be included 
on my report to the authors and, if the manuscript is accepted for publication, my named report  
including any attachments I upload will be posted on the websi te along with the authors' 
responses. I agree for my report to be made available under an Open Access Creative Commons  
CC-BY license ( http://creativecommons.org/licenses/by/4.0/ ). I understand that any comments 
which I do not wish to be included in my name d report can be in cluded as confidential comments 
to the editors, which will not be published.  
 
I agree to the open peer review policy of the journal  
assistant