Title: Acute idiopathic pancreatitis is associated with more aggressive disease course in Crohn’s
disease but not in ulcerative colitis
Version: 3 Date: 23 Mar 2023
Reviewer's report:
complements to the authors for a well written manuscript. I have few comments to make
1. Introduction: authors would consider changing EIM "approximately involves 24% of IBD"
to "involves Upto 24% of IBD"
2. Methodology: a figure on study flow would be helpful.
All inclusion criteria can be mentioned at one place..like only first case of AIP will be included
has been mentioned separately.
3. what would be the impact of Recurrent AIP if they were to be included for analysis
4. How do authors justify presence of such high numbers of EIM in CD patients.
5.DIscussion: authors can under play  findings like "A further observation of this study
demonstrated a statistically significant 10-fold increase in the risk of recurrence of acute
idiopathic pancreatitis in comparison to other causes of pancreatitis in UC patients". such
remarks in small sample study can be appear stretched.
Title: Acute idiopathic pancreatitis is associated with more aggressive disease course in Crohn’s
disease but not in ulcerative colitis
Version: 3 Date: 23 Mar 2023
Reviewer's report:
complements to the authors for a well written manuscript. I have few comments to make
1. Introduction: authors would consider changing EIM "approximately involves 24% of IBD"
to "involves Upto 24% of IBD"
2. Methodology: a figure on study flow would be helpful.
All inclusion criteria can be mentioned at one place..like only first case of AIP will be included
has been mentioned separately.
3. what would be the impact of Recurrent AIP if they were to be included for analysis
4. How do authors justify presence of such high numbers of EIM in CD patients.
5.DIscussion: authors can under play  findings like "A further observation of this study
demonstrated a statistically significant 10-fold increase in the risk of recurrence of acute
idiopathic pancreatitis in comparison to other causes of pancreatitis in UC patients". such
remarks in small sample study can be appear stretched.
Please review this paper.
user
Title: Acute idiopathic pancreatitis is associated with more aggressive disease course in Crohn’s
disease but not in ulcerative colitis
Version: 3 Date: 23 Mar 2023
Reviewer's report:
complements to the authors for a well written manuscript. I have few comments to make
1. Introduction: authors would consider changing EIM "approximately involves 24% of IBD"
to "involves Upto 24% of IBD"
2. Methodology: a figure on study flow would be helpful.
All inclusion criteria can be mentioned at one place..like only first case of AIP will be included
has been mentioned separately.
3. what would be the impact of Recurrent AIP if they were to be included for analysis
4. How do authors justify presence of such high numbers of EIM in CD patients.
5.DIscussion: authors can under play  findings like "A further observation of this study
demonstrated a statistically significant 10-fold increase in the risk of recurrence of acute
idiopathic pancreatitis in comparison to other causes of pancreatitis in UC patients". such
remarks in small sample study can be appear stretched.
assistant