Reviewer's report
Title:Threaded biliary inside stents are a safe and effective therapeutic option in
cases of malignant hilar obstruction.
Version: 2Date:26 October 2012
Reviewer: Rishi Pawa
Reviewer's report:
For distal biliary stricture (malignant), a fully covered metal stent is clearly
superior to a plastic stent or an uncovered metal stent due to higher patency
rates (requiring fewer interventions) and comparable rates of cholecystitis
(between covered and uncovered metal stents).
For malignant hilar strictures, covered metal stent is not an option. Numerous
studies have quoted better outcomes with uncovered metal stents as compared
to plastic stents. The idea of using a "Threaded Inside Stent" for malignant hilar
strictures appears very intriguing. The results published in this study are
promising, as these stents (TIS) not only have a comparable patency rate as
compared to metal stents, but also have significantly lower cost. However, larger
prospective trials need to be done before their (TIS) use becomes widely
accepted in clinical practice.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests.
Reviewer's report
Title:Threaded biliary inside stents are a safe and effective therapeutic option in
cases of malignant hilar obstruction.
Version: 2Date:26 October 2012
Reviewer: Rishi Pawa
Reviewer's report:
For distal biliary stricture (malignant), a fully covered metal stent is clearly
superior to a plastic stent or an uncovered metal stent due to higher patency
rates (requiring fewer interventions) and comparable rates of cholecystitis
(between covered and uncovered metal stents).
For malignant hilar strictures, covered metal stent is not an option. Numerous
studies have quoted better outcomes with uncovered metal stents as compared
to plastic stents. The idea of using a "Threaded Inside Stent" for malignant hilar
strictures appears very intriguing. The results published in this study are
promising, as these stents (TIS) not only have a comparable patency rate as
compared to metal stents, but also have significantly lower cost. However, larger
prospective trials need to be done before their (TIS) use becomes widely
accepted in clinical practice.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests.
Please review this paper.
user
Reviewer's report
Title:Threaded biliary inside stents are a safe and effective therapeutic option in
cases of malignant hilar obstruction.
Version: 2Date:26 October 2012
Reviewer: Rishi Pawa
Reviewer's report:
For distal biliary stricture (malignant), a fully covered metal stent is clearly
superior to a plastic stent or an uncovered metal stent due to higher patency
rates (requiring fewer interventions) and comparable rates of cholecystitis
(between covered and uncovered metal stents).
For malignant hilar strictures, covered metal stent is not an option. Numerous
studies have quoted better outcomes with uncovered metal stents as compared
to plastic stents. The idea of using a "Threaded Inside Stent" for malignant hilar
strictures appears very intriguing. The results published in this study are
promising, as these stents (TIS) not only have a comparable patency rate as
compared to metal stents, but also have significantly lower cost. However, larger
prospective trials need to be done before their (TIS) use becomes widely
accepted in clinical practice.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests.
assistant