Reviewer's report
Title:Association between HLA-DRB1 alleles polymorphism and hepatocellular
carcinoma:A Meta-analysis
Version: 5Date:6 August 2010
Reviewer: gilberto vargas-alarcon
Reviewer's report:
Considering that HLA-DRB1 allele polymorphisms have been reported to be
associated with hepatocellular carcinoma susceptibility with inconsistent results,
in the present work the authors explored whether specific HLA-DRB1 alleles
(DRB1*07, DRB1*12, DRB1*15) contribute to the susceptibility of hepatocellular
carcinoma by performing meta-analysis with the previously published data. This
is an interesting analysis with some limitations that are considered by the
authors.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests.
Reviewer's report
Title:Association between HLA-DRB1 alleles polymorphism and hepatocellular
carcinoma:A Meta-analysis
Version: 5Date:6 August 2010
Reviewer: gilberto vargas-alarcon
Reviewer's report:
Considering that HLA-DRB1 allele polymorphisms have been reported to be
associated with hepatocellular carcinoma susceptibility with inconsistent results,
in the present work the authors explored whether specific HLA-DRB1 alleles
(DRB1*07, DRB1*12, DRB1*15) contribute to the susceptibility of hepatocellular
carcinoma by performing meta-analysis with the previously published data. This
is an interesting analysis with some limitations that are considered by the
authors.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests.
Please review this paper.
user
Reviewer's report
Title:Association between HLA-DRB1 alleles polymorphism and hepatocellular
carcinoma:A Meta-analysis
Version: 5Date:6 August 2010
Reviewer: gilberto vargas-alarcon
Reviewer's report:
Considering that HLA-DRB1 allele polymorphisms have been reported to be
associated with hepatocellular carcinoma susceptibility with inconsistent results,
in the present work the authors explored whether specific HLA-DRB1 alleles
(DRB1*07, DRB1*12, DRB1*15) contribute to the susceptibility of hepatocellular
carcinoma by performing meta-analysis with the previously published data. This
is an interesting analysis with some limitations that are considered by the
authors.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests.
assistant