Title: Relationship between observation time and detection rate of focal lesions in
Esophagogastroduodenoscopy: a single-center, retrospective study
Version: 1 Date: 25 Oct 2023
Reviewer's report:
Review comments
Authors aimed to study a relationship between observation time and overall focal lesion
detection rate in upper GI endoscopy. Previous multiple studies have investigated similar
relationship not with overall but with neoplastic lesion. I think the idea is interesting. I would
like to have some comments.
- Please clarify the reason why has surveillance endoscopy been excluded? They may have more
neoplastic lesions.
- Please clarify the reason why you decided 5min as a cut-off time.
- This is a retrospective observational study. How did you obtain informed consent from 13000
participants?
- In this study, gastric lesion included not “focal” lesions for example, atrophic gastritis or Barrett
esophagus. This may have confused and influenced the result. Please consider analyzing  the
result without these findings. And why slow endoscopists had a higher detection rate of atrophic
gastritis while fast ones had a high rate of intestinal metaplasia? This should be discussed.
- ‘The focal lesion detection rate was strongly correlated with the biopsy rate.’ I think this is
not a significant result because it is obvious that biopsy will be performed after detection of the
lesion. Or authors meant anything different from this result?
- Regarding Table 4, what was the proportion of expert in each fast and slow group? Please
explain why in table 4, expert resulted as a negative factor associated with detection of focal
lesions. And in the table slow group was a negative factor, why?
Title: Relationship between observation time and detection rate of focal lesions in
Esophagogastroduodenoscopy: a single-center, retrospective study
Version: 1 Date: 25 Oct 2023
Reviewer's report:
Review comments
Authors aimed to study a relationship between observation time and overall focal lesion
detection rate in upper GI endoscopy. Previous multiple studies have investigated similar
relationship not with overall but with neoplastic lesion. I think the idea is interesting. I would
like to have some comments.
- Please clarify the reason why has surveillance endoscopy been excluded? They may have more
neoplastic lesions.
- Please clarify the reason why you decided 5min as a cut-off time.
- This is a retrospective observational study. How did you obtain informed consent from 13000
participants?
- In this study, gastric lesion included not “focal” lesions for example, atrophic gastritis or Barrett
esophagus. This may have confused and influenced the result. Please consider analyzing  the
result without these findings. And why slow endoscopists had a higher detection rate of atrophic
gastritis while fast ones had a high rate of intestinal metaplasia? This should be discussed.
- ‘The focal lesion detection rate was strongly correlated with the biopsy rate.’ I think this is
not a significant result because it is obvious that biopsy will be performed after detection of the
lesion. Or authors meant anything different from this result?
- Regarding Table 4, what was the proportion of expert in each fast and slow group? Please
explain why in table 4, expert resulted as a negative factor associated with detection of focal
lesions. And in the table slow group was a negative factor, why?
Please review this paper.
user
Title: Relationship between observation time and detection rate of focal lesions in
Esophagogastroduodenoscopy: a single-center, retrospective study
Version: 1 Date: 25 Oct 2023
Reviewer's report:
Review comments
Authors aimed to study a relationship between observation time and overall focal lesion
detection rate in upper GI endoscopy. Previous multiple studies have investigated similar
relationship not with overall but with neoplastic lesion. I think the idea is interesting. I would
like to have some comments.
- Please clarify the reason why has surveillance endoscopy been excluded? They may have more
neoplastic lesions.
- Please clarify the reason why you decided 5min as a cut-off time.
- This is a retrospective observational study. How did you obtain informed consent from 13000
participants?
- In this study, gastric lesion included not “focal” lesions for example, atrophic gastritis or Barrett
esophagus. This may have confused and influenced the result. Please consider analyzing  the
result without these findings. And why slow endoscopists had a higher detection rate of atrophic
gastritis while fast ones had a high rate of intestinal metaplasia? This should be discussed.
- ‘The focal lesion detection rate was strongly correlated with the biopsy rate.’ I think this is
not a significant result because it is obvious that biopsy will be performed after detection of the
lesion. Or authors meant anything different from this result?
- Regarding Table 4, what was the proportion of expert in each fast and slow group? Please
explain why in table 4, expert resulted as a negative factor associated with detection of focal
lesions. And in the table slow group was a negative factor, why?
assistant