Title: The Diagnostic Value of MRI-PDFF in Hepatic Steatosis of Patients with metabolic
dysfunction-associated steatotic liver disease: A Systematic Review and Meta-Analysis
Version: 1 Date: 22 Mar 2025
Reviewer's report:
The paper "The Diagnostic Value of MRI-PDFF in Hepatic Steatosis of Patients with
Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis" aims to evaluate
the diagnostic efficacy of MRI-PDFF in assessing hepatic steatosis through systematic review
and meta-analysis approaches.
The main limitation of the paper is the term NAFLD is not current. The term MASLD and related
ones should be used.
A recent study "Azizi N, Naghibi H, Shakiba M, Morsali M, Zarei D, Abbastabar H, Ghanaati
H. Evaluation of MRI proton density fat fraction in hepatic steatosis: a systematic review and
meta-analysis. Eur Radiol. 2025"  is a more comprehensive study than the author's study that
reduces the impact of the present study.
Many more studies are available in the literature that can be suitable for this analysis (see the
reference above). There should be a more comprehensive explanation of why they did not meet
the criteria.
Title: The Diagnostic Value of MRI-PDFF in Hepatic Steatosis of Patients with metabolic
dysfunction-associated steatotic liver disease: A Systematic Review and Meta-Analysis
Version: 1 Date: 22 Mar 2025
Reviewer's report:
The paper "The Diagnostic Value of MRI-PDFF in Hepatic Steatosis of Patients with
Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis" aims to evaluate
the diagnostic efficacy of MRI-PDFF in assessing hepatic steatosis through systematic review
and meta-analysis approaches.
The main limitation of the paper is the term NAFLD is not current. The term MASLD and related
ones should be used.
A recent study "Azizi N, Naghibi H, Shakiba M, Morsali M, Zarei D, Abbastabar H, Ghanaati
H. Evaluation of MRI proton density fat fraction in hepatic steatosis: a systematic review and
meta-analysis. Eur Radiol. 2025"  is a more comprehensive study than the author's study that
reduces the impact of the present study.
Many more studies are available in the literature that can be suitable for this analysis (see the
reference above). There should be a more comprehensive explanation of why they did not meet
the criteria.
Please review this paper.
user
Title: The Diagnostic Value of MRI-PDFF in Hepatic Steatosis of Patients with metabolic
dysfunction-associated steatotic liver disease: A Systematic Review and Meta-Analysis
Version: 1 Date: 22 Mar 2025
Reviewer's report:
The paper "The Diagnostic Value of MRI-PDFF in Hepatic Steatosis of Patients with
Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis" aims to evaluate
the diagnostic efficacy of MRI-PDFF in assessing hepatic steatosis through systematic review
and meta-analysis approaches.
The main limitation of the paper is the term NAFLD is not current. The term MASLD and related
ones should be used.
A recent study "Azizi N, Naghibi H, Shakiba M, Morsali M, Zarei D, Abbastabar H, Ghanaati
H. Evaluation of MRI proton density fat fraction in hepatic steatosis: a systematic review and
meta-analysis. Eur Radiol. 2025"  is a more comprehensive study than the author's study that
reduces the impact of the present study.
Many more studies are available in the literature that can be suitable for this analysis (see the
reference above). There should be a more comprehensive explanation of why they did not meet
the criteria.
assistant