Reviewer’s report
Title:  Small bowel metastasis from pulmonary rhabdomyosarcoma causing intussusception: a case  
report
Version: 1 Date: 25 Mar 2019
Reviewer: Fedja Rochling
Reviewer's report:
Please include all comments for the authors in this box rather than uploading your report as an  
attachment. Please only upload as attachments annotated versions of manuscripts, graphs, supporting  
materials or other aspects of your report which cannot be included in a text format.
Please overwrite this text when adding your comments to the authors.
Comments
By Fedja Rochling MB BCh (NUI) MBA
Small bowel metastasis from pulmonary rhabdomyosarcoma causing intussusception: a case report
1.Line 28 term "Extension study" should be reconsidered
a.Comment
b.Would replace with something like " staging was performed using gastroscopy etc …"
2.Line 113
a.RMS is highly aggressive and metastatic.
b.Comment: would remove
3.Line 121: Small bowel metastases are clinical manifestations of an advanced tumor
a.Comment: this statement is very general. Any metastasis is advanced tumor burden by  
definition. Suggest to remove the sentence
4.Line 132: 
a.should be revised as the submitted case report is probably the 2nd report for this kind of  
presentation
b.Another case report was noted upon search of literature
c.Pleomorphic rhabdomyosarcoma metastasis to small intestine causing intussusception: A  
case report. Xi S, Tong W. Medicine (Baltimore). 2018 Dec;97(51): PMID: 30572480
5.References
a.Could also include
b.AJR Am J Roentgenol. 2017 Aug;209(2):409-416. doi: 10.2214/AJR.16.17466. Epub  
2017 Jun 7. Rhabdomyosarcoma in Children and Adolescents: Patterns and Risk Factors  
of Distant Metastasis. Kim JR1, Yoon HM1, Koh KN2, Jung AY1, Cho YA1, Lee JS1.
c.https://www-ajronline-org.library1.unmc.edu/doi/full/10.2214/AJR.16.17466
Are the methods appropriate and well described?
If not, please specify what is required in your comments to the authors.
Yes
Does the work include the necessary controls?
If not, please specify which controls are required in your comments to the authors.
Yes
Are the conclusions drawn adequately supported by the data shown?
If not, please explain in your comments to the authors.
No
Are you able to assess any statistics in the manuscript or would you recommend an additional  
statistical review?
If  an  additional  statistical  review  is  recommended,  please  specify  what  aspects  require  further  
assessment in your comments to the editors.
Not relevant to this manuscript
Quality of written English
Please indicate the quality of language in the manuscript:
Acceptable
Declaration of competing interests
Please complete a declaration of competing interests, considering the following questions:
1. Have you in the past five years received reimbursements, fees, funding, or salary from an  
organisation  that  may  in  any  way  gain  or  lose  financially  from  the  publication  of  this  
manuscript, either now or in the future?
2. Do you hold any stocks or shares in an organisation that may in any way gain or lose financially  
from the publication of this manuscript, either now or in the future?
3. Do  you  hold  or are  you  currently applying  for  any patents  relating  to  the  content  of  the  
manuscript?
4. Have you received reimbursements, fees, funding, or salary from an organization that holds or  
has applied for patents relating to the content of the manuscript?
5. Do you have any other financial competing interests?
6. Do you have any non-financial competing interests in relation to this paper?
If you can answer no to all of the above, write 'I declare that I have no competing interests' below. If  
your reply is yes to any, please give details below.
'I declare that I have no competing interests
I agree to the open peer review policy of the journal. I understand that my name will be included on my  
report to the authors and, if the manuscript is accepted for publication, my named report including any 
attachments I upload will be posted on the website along with the authors' responses. I agree for my 
report to be made available under an Open Access Creative Commons CC-BY license 
(http://creativecommons.org/licenses/by/4.0/ ). I understand that any comments which I do not wish to 
be included in my named report can be included as confidential comments to the editors, which will not  
be published.
I agree to the open peer review policy of the journal
Reviewer’s report
Title:  Small bowel metastasis from pulmonary rhabdomyosarcoma causing intussusception: a case  
report
Version: 1 Date: 25 Mar 2019
Reviewer: Fedja Rochling
Reviewer's report:
Please include all comments for the authors in this box rather than uploading your report as an  
attachment. Please only upload as attachments annotated versions of manuscripts, graphs, supporting  
materials or other aspects of your report which cannot be included in a text format.
Please overwrite this text when adding your comments to the authors.
Comments
By Fedja Rochling MB BCh (NUI) MBA
Small bowel metastasis from pulmonary rhabdomyosarcoma causing intussusception: a case report
1.Line 28 term "Extension study" should be reconsidered
a.Comment
b.Would replace with something like " staging was performed using gastroscopy etc …"
2.Line 113
a.RMS is highly aggressive and metastatic.
b.Comment: would remove
3.Line 121: Small bowel metastases are clinical manifestations of an advanced tumor
a.Comment: this statement is very general. Any metastasis is advanced tumor burden by  
definition. Suggest to remove the sentence
4.Line 132: 
a.should be revised as the submitted case report is probably the 2nd report for this kind of  
presentation
b.Another case report was noted upon search of literature
c.Pleomorphic rhabdomyosarcoma metastasis to small intestine causing intussusception: A  
case report. Xi S, Tong W. Medicine (Baltimore). 2018 Dec;97(51): PMID: 30572480
5.References
a.Could also include
b.AJR Am J Roentgenol. 2017 Aug;209(2):409-416. doi: 10.2214/AJR.16.17466. Epub  
2017 Jun 7. Rhabdomyosarcoma in Children and Adolescents: Patterns and Risk Factors  
of Distant Metastasis. Kim JR1, Yoon HM1, Koh KN2, Jung AY1, Cho YA1, Lee JS1.
c.https://www-ajronline-org.library1.unmc.edu/doi/full/10.2214/AJR.16.17466
Are the methods appropriate and well described?
If not, please specify what is required in your comments to the authors.
Yes
Does the work include the necessary controls?
If not, please specify which controls are required in your comments to the authors.
Yes
Are the conclusions drawn adequately supported by the data shown?
If not, please explain in your comments to the authors.
No
Are you able to assess any statistics in the manuscript or would you recommend an additional  
statistical review?
If  an  additional  statistical  review  is  recommended,  please  specify  what  aspects  require  further  
assessment in your comments to the editors.
Not relevant to this manuscript
Quality of written English
Please indicate the quality of language in the manuscript:
Acceptable
Declaration of competing interests
Please complete a declaration of competing interests, considering the following questions:
1. Have you in the past five years received reimbursements, fees, funding, or salary from an  
organisation  that  may  in  any  way  gain  or  lose  financially  from  the  publication  of  this  
manuscript, either now or in the future?
2. Do you hold any stocks or shares in an organisation that may in any way gain or lose financially  
from the publication of this manuscript, either now or in the future?
3. Do  you  hold  or are  you  currently applying  for  any patents  relating  to  the  content  of  the  
manuscript?
4. Have you received reimbursements, fees, funding, or salary from an organization that holds or  
has applied for patents relating to the content of the manuscript?
5. Do you have any other financial competing interests?
6. Do you have any non-financial competing interests in relation to this paper?
If you can answer no to all of the above, write 'I declare that I have no competing interests' below. If  
your reply is yes to any, please give details below.
'I declare that I have no competing interests
I agree to the open peer review policy of the journal. I understand that my name will be included on my  
report to the authors and, if the manuscript is accepted for publication, my named report including any 
attachments I upload will be posted on the website along with the authors' responses. I agree for my 
report to be made available under an Open Access Creative Commons CC-BY license 
(http://creativecommons.org/licenses/by/4.0/ ). I understand that any comments which I do not wish to 
be included in my named report can be included as confidential comments to the editors, which will not  
be published.
I agree to the open peer review policy of the journal
Please review this paper.
user
Reviewer’s report
Title:  Small bowel metastasis from pulmonary rhabdomyosarcoma causing intussusception: a case  
report
Version: 1 Date: 25 Mar 2019
Reviewer: Fedja Rochling
Reviewer's report:
Please include all comments for the authors in this box rather than uploading your report as an  
attachment. Please only upload as attachments annotated versions of manuscripts, graphs, supporting  
materials or other aspects of your report which cannot be included in a text format.
Please overwrite this text when adding your comments to the authors.
Comments
By Fedja Rochling MB BCh (NUI) MBA
Small bowel metastasis from pulmonary rhabdomyosarcoma causing intussusception: a case report
1.Line 28 term "Extension study" should be reconsidered
a.Comment
b.Would replace with something like " staging was performed using gastroscopy etc …"
2.Line 113
a.RMS is highly aggressive and metastatic.
b.Comment: would remove
3.Line 121: Small bowel metastases are clinical manifestations of an advanced tumor
a.Comment: this statement is very general. Any metastasis is advanced tumor burden by  
definition. Suggest to remove the sentence
4.Line 132: 
a.should be revised as the submitted case report is probably the 2nd report for this kind of  
presentation
b.Another case report was noted upon search of literature
c.Pleomorphic rhabdomyosarcoma metastasis to small intestine causing intussusception: A  
case report. Xi S, Tong W. Medicine (Baltimore). 2018 Dec;97(51): PMID: 30572480
5.References
a.Could also include
b.AJR Am J Roentgenol. 2017 Aug;209(2):409-416. doi: 10.2214/AJR.16.17466. Epub  
2017 Jun 7. Rhabdomyosarcoma in Children and Adolescents: Patterns and Risk Factors  
of Distant Metastasis. Kim JR1, Yoon HM1, Koh KN2, Jung AY1, Cho YA1, Lee JS1.
c.https://www-ajronline-org.library1.unmc.edu/doi/full/10.2214/AJR.16.17466
Are the methods appropriate and well described?
If not, please specify what is required in your comments to the authors.
Yes
Does the work include the necessary controls?
If not, please specify which controls are required in your comments to the authors.
Yes
Are the conclusions drawn adequately supported by the data shown?
If not, please explain in your comments to the authors.
No
Are you able to assess any statistics in the manuscript or would you recommend an additional  
statistical review?
If  an  additional  statistical  review  is  recommended,  please  specify  what  aspects  require  further  
assessment in your comments to the editors.
Not relevant to this manuscript
Quality of written English
Please indicate the quality of language in the manuscript:
Acceptable
Declaration of competing interests
Please complete a declaration of competing interests, considering the following questions:
1. Have you in the past five years received reimbursements, fees, funding, or salary from an  
organisation  that  may  in  any  way  gain  or  lose  financially  from  the  publication  of  this  
manuscript, either now or in the future?
2. Do you hold any stocks or shares in an organisation that may in any way gain or lose financially  
from the publication of this manuscript, either now or in the future?
3. Do  you  hold  or are  you  currently applying  for  any patents  relating  to  the  content  of  the  
manuscript?
4. Have you received reimbursements, fees, funding, or salary from an organization that holds or  
has applied for patents relating to the content of the manuscript?
5. Do you have any other financial competing interests?
6. Do you have any non-financial competing interests in relation to this paper?
If you can answer no to all of the above, write 'I declare that I have no competing interests' below. If  
your reply is yes to any, please give details below.
'I declare that I have no competing interests
I agree to the open peer review policy of the journal. I understand that my name will be included on my  
report to the authors and, if the manuscript is accepted for publication, my named report including any 
attachments I upload will be posted on the website along with the authors' responses. I agree for my 
report to be made available under an Open Access Creative Commons CC-BY license 
(http://creativecommons.org/licenses/by/4.0/ ). I understand that any comments which I do not wish to 
be included in my named report can be included as confidential comments to the editors, which will not  
be published.
I agree to the open peer review policy of the journal
assistant