Title: Correlation of MKI67 with Prognosis, Immune Infiltration, and T Cell Exhaustion in
Hepatocellular Carcinoma
Version: 1 Date: 24 Aug 2021
Reviewer's report:
Interesting work.
My only recommendations are about the discussion that should be improved:
1) More insights on the pathogenesis of HCC should be provided. On this regard, cite and
comment the following papers:
- PMID: 29220698 on the molecular mechanisms in the setting of HCC on NAFLD progression
- PMID: 28976021 on fibrosis progression in HCV patients
- PMID: 23845075 on role of metabolic factors and diabetes in immunomodulation in HCC
- PMID: 25974743 on the role of angiotensin pathway in fibrosis progression
Title: Correlation of MKI67 with Prognosis, Immune Infiltration, and T Cell Exhaustion in
Hepatocellular Carcinoma
Version: 1 Date: 24 Aug 2021
Reviewer's report:
Interesting work.
My only recommendations are about the discussion that should be improved:
1) More insights on the pathogenesis of HCC should be provided. On this regard, cite and
comment the following papers:
- PMID: 29220698 on the molecular mechanisms in the setting of HCC on NAFLD progression
- PMID: 28976021 on fibrosis progression in HCV patients
- PMID: 23845075 on role of metabolic factors and diabetes in immunomodulation in HCC
- PMID: 25974743 on the role of angiotensin pathway in fibrosis progression
Please review this paper.
user
Title: Correlation of MKI67 with Prognosis, Immune Infiltration, and T Cell Exhaustion in
Hepatocellular Carcinoma
Version: 1 Date: 24 Aug 2021
Reviewer's report:
Interesting work.
My only recommendations are about the discussion that should be improved:
1) More insights on the pathogenesis of HCC should be provided. On this regard, cite and
comment the following papers:
- PMID: 29220698 on the molecular mechanisms in the setting of HCC on NAFLD progression
- PMID: 28976021 on fibrosis progression in HCV patients
- PMID: 23845075 on role of metabolic factors and diabetes in immunomodulation in HCC
- PMID: 25974743 on the role of angiotensin pathway in fibrosis progression
assistant