Reviewer's report
Title:The actin-bundling protein Fascin is overexpressed in inflammatory bowel
disease and may be important in tissue repair.
Version: 2Date:19 January 2011
Reviewer: Evanthia Kostopoulou
Reviewer's report:
The present paper is dealing with the interesting subject of fascin expression in
IBD, including the effects of therapeutic modalities on this expression.
It is an interesting study and most of the previously suggested points for major
revision have been addressed by the authors.
Concerning previous suggestions for discretionary revisions, the authors have
chosen not to add any comment for Ki67 labelling or EMT, especially since,
according to their opinion, examining proliferation in the current study material
would require extensive investigation, beyond the scope of the present study.
Their decision does not affect the quality of the paper concerning publication,
although a reference might be added concerning the relevant data (for Ki67)
described by the authors in their coverletter.
According to my opinion, the present study could be accepted for publication in
BMC Gastroenterology and constitutes a useful contribution to the field, which
may prove to be of importance.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests
Reviewer's report
Title:The actin-bundling protein Fascin is overexpressed in inflammatory bowel
disease and may be important in tissue repair.
Version: 2Date:19 January 2011
Reviewer: Evanthia Kostopoulou
Reviewer's report:
The present paper is dealing with the interesting subject of fascin expression in
IBD, including the effects of therapeutic modalities on this expression.
It is an interesting study and most of the previously suggested points for major
revision have been addressed by the authors.
Concerning previous suggestions for discretionary revisions, the authors have
chosen not to add any comment for Ki67 labelling or EMT, especially since,
according to their opinion, examining proliferation in the current study material
would require extensive investigation, beyond the scope of the present study.
Their decision does not affect the quality of the paper concerning publication,
although a reference might be added concerning the relevant data (for Ki67)
described by the authors in their coverletter.
According to my opinion, the present study could be accepted for publication in
BMC Gastroenterology and constitutes a useful contribution to the field, which
may prove to be of importance.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests
Please review this paper.
user
Reviewer's report
Title:The actin-bundling protein Fascin is overexpressed in inflammatory bowel
disease and may be important in tissue repair.
Version: 2Date:19 January 2011
Reviewer: Evanthia Kostopoulou
Reviewer's report:
The present paper is dealing with the interesting subject of fascin expression in
IBD, including the effects of therapeutic modalities on this expression.
It is an interesting study and most of the previously suggested points for major
revision have been addressed by the authors.
Concerning previous suggestions for discretionary revisions, the authors have
chosen not to add any comment for Ki67 labelling or EMT, especially since,
according to their opinion, examining proliferation in the current study material
would require extensive investigation, beyond the scope of the present study.
Their decision does not affect the quality of the paper concerning publication,
although a reference might be added concerning the relevant data (for Ki67)
described by the authors in their coverletter.
According to my opinion, the present study could be accepted for publication in
BMC Gastroenterology and constitutes a useful contribution to the field, which
may prove to be of importance.
Level of interest: An article of importance in its field
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests
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