Title: Effects of probiotics in elderly hospitalized tube-fed patients with antibiotics use
Version: 3 Date: 25 Sep 2024
Reviewer's report:
Abstract
- Methods: change the highlighted verb from singular to plural in the excerpt: "the probiotics
WAS continued to use for an additional 7 days after completion of antibiotics therapy";
- Results: change the highlighted word from singular to plural in the excerpt: "11 patients
completed the study in both GROUP";
- Conclusion: according to the Results, there was a significant difference in the stool frequency
for the probiotic group. No significant differences were found in the stool form. This only
occurred during the follow-up period (4 weeks), but this is not clear in the Conclusion, causing
confusion.
Text
- Methods: change the highlighted word from singular to plural in the excerpt:  "Both GROUP
had patient who failed to complete the study either due to the use of antibiotics for more than
14 days or personal reasons.";
-- In the "Data collection" subsection did not describe which data were collected within each
category: anthropometric, laboratory, medication, and nutrient intake. Therefore, it is impossible
for the study to be repeated;
-- In the "Statistical methods" subsection, the power of the test was very low, not reaching the
minimum recommended in the literature, which is 0.8 or 80%. I suggest looking in the literature
for a justification to further support the relevance of the results found.;
- Results:  This excerpt should be rewritten to conform to the formal norms of the English
language: "There were no significant differences were observed in baseline characteristics
between the two groups". Suggestion: "There were no significant differences in baseline
characteristics between the two groups";
-- This excerpt does not present the data that confirms your statement: "During the follow-up
period of the probiotic group (a total of 4 weeks), the stool form significantly differed compared
to both the beginning and end of antibiotics therapy";
- Discussion: change the highlighted word from singular to plural in the excerpt:"We found that
the PATIENT in both groups were moderate malnutrition risk as both have a score over 3";
-- This excerpt should be rewritten to conform to the formal norms of the English language:
"Increasing amount of evidences indicates that critical illnes...". Suggestion:  "A growing body
of evidence indicates that critical illnes...";
-- Change the highlighted word from plural to singular in the excerpt: "Lastly, we didn’t design
the comparison between different compositions or dosages of the PROBIOTICS strains.";
- Conclusion: the Conclusion needs to be rewritten to agree with the Objectives of the study, as
it does not provide any conclusions regarding nutritional status.
In addition, the Conclusion is about the prolonged effects of the probiotic after the end of
antibiotic treatment, but this is not clear and the information seems to be about the effects of the
probiotics during antibiotic use, which influences stool frequency and not stool form.
Title: Effects of probiotics in elderly hospitalized tube-fed patients with antibiotics use
Version: 3 Date: 25 Sep 2024
Reviewer's report:
Abstract
- Methods: change the highlighted verb from singular to plural in the excerpt: "the probiotics
WAS continued to use for an additional 7 days after completion of antibiotics therapy";
- Results: change the highlighted word from singular to plural in the excerpt: "11 patients
completed the study in both GROUP";
- Conclusion: according to the Results, there was a significant difference in the stool frequency
for the probiotic group. No significant differences were found in the stool form. This only
occurred during the follow-up period (4 weeks), but this is not clear in the Conclusion, causing
confusion.
Text
- Methods: change the highlighted word from singular to plural in the excerpt:  "Both GROUP
had patient who failed to complete the study either due to the use of antibiotics for more than
14 days or personal reasons.";
-- In the "Data collection" subsection did not describe which data were collected within each
category: anthropometric, laboratory, medication, and nutrient intake. Therefore, it is impossible
for the study to be repeated;
-- In the "Statistical methods" subsection, the power of the test was very low, not reaching the
minimum recommended in the literature, which is 0.8 or 80%. I suggest looking in the literature
for a justification to further support the relevance of the results found.;
- Results:  This excerpt should be rewritten to conform to the formal norms of the English
language: "There were no significant differences were observed in baseline characteristics
between the two groups". Suggestion: "There were no significant differences in baseline
characteristics between the two groups";
-- This excerpt does not present the data that confirms your statement: "During the follow-up
period of the probiotic group (a total of 4 weeks), the stool form significantly differed compared
to both the beginning and end of antibiotics therapy";
- Discussion: change the highlighted word from singular to plural in the excerpt:"We found that
the PATIENT in both groups were moderate malnutrition risk as both have a score over 3";
-- This excerpt should be rewritten to conform to the formal norms of the English language:
"Increasing amount of evidences indicates that critical illnes...". Suggestion:  "A growing body
of evidence indicates that critical illnes...";
-- Change the highlighted word from plural to singular in the excerpt: "Lastly, we didn’t design
the comparison between different compositions or dosages of the PROBIOTICS strains.";
- Conclusion: the Conclusion needs to be rewritten to agree with the Objectives of the study, as
it does not provide any conclusions regarding nutritional status.
In addition, the Conclusion is about the prolonged effects of the probiotic after the end of
antibiotic treatment, but this is not clear and the information seems to be about the effects of the
probiotics during antibiotic use, which influences stool frequency and not stool form.
Please review this paper.
user
Title: Effects of probiotics in elderly hospitalized tube-fed patients with antibiotics use
Version: 3 Date: 25 Sep 2024
Reviewer's report:
Abstract
- Methods: change the highlighted verb from singular to plural in the excerpt: "the probiotics
WAS continued to use for an additional 7 days after completion of antibiotics therapy";
- Results: change the highlighted word from singular to plural in the excerpt: "11 patients
completed the study in both GROUP";
- Conclusion: according to the Results, there was a significant difference in the stool frequency
for the probiotic group. No significant differences were found in the stool form. This only
occurred during the follow-up period (4 weeks), but this is not clear in the Conclusion, causing
confusion.
Text
- Methods: change the highlighted word from singular to plural in the excerpt:  "Both GROUP
had patient who failed to complete the study either due to the use of antibiotics for more than
14 days or personal reasons.";
-- In the "Data collection" subsection did not describe which data were collected within each
category: anthropometric, laboratory, medication, and nutrient intake. Therefore, it is impossible
for the study to be repeated;
-- In the "Statistical methods" subsection, the power of the test was very low, not reaching the
minimum recommended in the literature, which is 0.8 or 80%. I suggest looking in the literature
for a justification to further support the relevance of the results found.;
- Results:  This excerpt should be rewritten to conform to the formal norms of the English
language: "There were no significant differences were observed in baseline characteristics
between the two groups". Suggestion: "There were no significant differences in baseline
characteristics between the two groups";
-- This excerpt does not present the data that confirms your statement: "During the follow-up
period of the probiotic group (a total of 4 weeks), the stool form significantly differed compared
to both the beginning and end of antibiotics therapy";
- Discussion: change the highlighted word from singular to plural in the excerpt:"We found that
the PATIENT in both groups were moderate malnutrition risk as both have a score over 3";
-- This excerpt should be rewritten to conform to the formal norms of the English language:
"Increasing amount of evidences indicates that critical illnes...". Suggestion:  "A growing body
of evidence indicates that critical illnes...";
-- Change the highlighted word from plural to singular in the excerpt: "Lastly, we didn’t design
the comparison between different compositions or dosages of the PROBIOTICS strains.";
- Conclusion: the Conclusion needs to be rewritten to agree with the Objectives of the study, as
it does not provide any conclusions regarding nutritional status.
In addition, the Conclusion is about the prolonged effects of the probiotic after the end of
antibiotic treatment, but this is not clear and the information seems to be about the effects of the
probiotics during antibiotic use, which influences stool frequency and not stool form.
assistant