Reviewer's report
Title:Inflammatory bowel disease (IBD)-like disease in a case of a 33-year old
man with glycogenosis 1b
Version:2Date:3 February 2015
Reviewer: Heyson Chan
Reviewer's report:
The authors described a rare case of IBD-like condition in GSD type 1b which is
of interest to the field of IBD. Of particular note, they describe such case in an
adult, in contrast to the mostly reported case in pediatric population. This case
also differs from previously reported cases as the intestinal symptoms of this
case did not respond to G-CSF treatment. The authors have provided reasonable
review and explanations to the possible reasons contributing to failure of G-CSF
treatment in this case.
Several grammatical mistakes were spotted. It is advisable for the authors to
review the written English before publishing. The mistakes spotted were
summarized in the minor essential revisions section.
Overall, the authors have described an interesting case with reasonable review
of available literature. I recommend accepting the manuscript after the minor
essential revisions.
Minor Essential Revisions
- line 25: replace glycogenosis - change to GSD
- line 32, line 58, line 62, line 77: use "transverse colon" instead of "transversing
colon"
- line 48: please spell out "inflammatory bowel disease" when "IBD" first appear
in the main text
- line 55, 56: move "pancytopenia may occur with GSD 1b" to line 47 to make it
follow other described characteristics of the disease
- line 66: the type of "TNF-alpha" cannot be showed up - consider spelling it out
or reinsert the "alpha" symbol
- The "conclusion" part is too long. I suppose this is "Discussion" part. Please add
a few sentences to the "conclusion" part instead
- line 85: we describe "a" (instead of "the") case....
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
No to all of the above
Reviewer's report
Title:Inflammatory bowel disease (IBD)-like disease in a case of a 33-year old
man with glycogenosis 1b
Version:2Date:3 February 2015
Reviewer: Heyson Chan
Reviewer's report:
The authors described a rare case of IBD-like condition in GSD type 1b which is
of interest to the field of IBD. Of particular note, they describe such case in an
adult, in contrast to the mostly reported case in pediatric population. This case
also differs from previously reported cases as the intestinal symptoms of this
case did not respond to G-CSF treatment. The authors have provided reasonable
review and explanations to the possible reasons contributing to failure of G-CSF
treatment in this case.
Several grammatical mistakes were spotted. It is advisable for the authors to
review the written English before publishing. The mistakes spotted were
summarized in the minor essential revisions section.
Overall, the authors have described an interesting case with reasonable review
of available literature. I recommend accepting the manuscript after the minor
essential revisions.
Minor Essential Revisions
- line 25: replace glycogenosis - change to GSD
- line 32, line 58, line 62, line 77: use "transverse colon" instead of "transversing
colon"
- line 48: please spell out "inflammatory bowel disease" when "IBD" first appear
in the main text
- line 55, 56: move "pancytopenia may occur with GSD 1b" to line 47 to make it
follow other described characteristics of the disease
- line 66: the type of "TNF-alpha" cannot be showed up - consider spelling it out
or reinsert the "alpha" symbol
- The "conclusion" part is too long. I suppose this is "Discussion" part. Please add
a few sentences to the "conclusion" part instead
- line 85: we describe "a" (instead of "the") case....
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
No to all of the above
Please review this paper.
user
Reviewer's report
Title:Inflammatory bowel disease (IBD)-like disease in a case of a 33-year old
man with glycogenosis 1b
Version:2Date:3 February 2015
Reviewer: Heyson Chan
Reviewer's report:
The authors described a rare case of IBD-like condition in GSD type 1b which is
of interest to the field of IBD. Of particular note, they describe such case in an
adult, in contrast to the mostly reported case in pediatric population. This case
also differs from previously reported cases as the intestinal symptoms of this
case did not respond to G-CSF treatment. The authors have provided reasonable
review and explanations to the possible reasons contributing to failure of G-CSF
treatment in this case.
Several grammatical mistakes were spotted. It is advisable for the authors to
review the written English before publishing. The mistakes spotted were
summarized in the minor essential revisions section.
Overall, the authors have described an interesting case with reasonable review
of available literature. I recommend accepting the manuscript after the minor
essential revisions.
Minor Essential Revisions
- line 25: replace glycogenosis - change to GSD
- line 32, line 58, line 62, line 77: use "transverse colon" instead of "transversing
colon"
- line 48: please spell out "inflammatory bowel disease" when "IBD" first appear
in the main text
- line 55, 56: move "pancytopenia may occur with GSD 1b" to line 47 to make it
follow other described characteristics of the disease
- line 66: the type of "TNF-alpha" cannot be showed up - consider spelling it out
or reinsert the "alpha" symbol
- The "conclusion" part is too long. I suppose this is "Discussion" part. Please add
a few sentences to the "conclusion" part instead
- line 85: we describe "a" (instead of "the") case....
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
No to all of the above
assistant