Reviewer's report
Title:Intraductal papillary mucinous carcinoma of the pancreas associated with
pancreas divisum: a case report and review of the literature
Version:3Date:21 April 2015
Reviewer: Puneet Dhar
Reviewer's report:
Interesting case report of a combination of IPMN occurring with pancreas
divisum. Other published cases reporting this combination have also been
reviewed. The difference here is the presentation in the ventral anlage of
pancreas.
Discretionary Revisions:
1. There is a significant overlap of reviewed cases with a previous publication
from Italy (Zippi and Quarto, J Gastroint Dig Syst 2014, 4:171 available online at
http://dx.doi.org/10.4172/2161-069X.1000171). The current submission has 12 of
the cases in Table 1 mentioned in a table in the earlier publication (omitting 1). It
may be preferable to allude to this publication and tabulate only the 2 fresh cases
added in this submission.
2. The diagnosis of Pancreas divisum has been established in the reported case
by ERCP . However since there is a coexistent tumour (IPMN here, it is possible
that it is incomplete divisum and the connection with main pancreatic duct has
been obscured by tumour obstruction. It may not be the case - but the possibility
should be alluded to.
3. Color images may be preferable especially in the pathology and endoscopy
images!
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
No conflict of interest
Reviewer's report
Title:Intraductal papillary mucinous carcinoma of the pancreas associated with
pancreas divisum: a case report and review of the literature
Version:3Date:21 April 2015
Reviewer: Puneet Dhar
Reviewer's report:
Interesting case report of a combination of IPMN occurring with pancreas
divisum. Other published cases reporting this combination have also been
reviewed. The difference here is the presentation in the ventral anlage of
pancreas.
Discretionary Revisions:
1. There is a significant overlap of reviewed cases with a previous publication
from Italy (Zippi and Quarto, J Gastroint Dig Syst 2014, 4:171 available online at
http://dx.doi.org/10.4172/2161-069X.1000171). The current submission has 12 of
the cases in Table 1 mentioned in a table in the earlier publication (omitting 1). It
may be preferable to allude to this publication and tabulate only the 2 fresh cases
added in this submission.
2. The diagnosis of Pancreas divisum has been established in the reported case
by ERCP . However since there is a coexistent tumour (IPMN here, it is possible
that it is incomplete divisum and the connection with main pancreatic duct has
been obscured by tumour obstruction. It may not be the case - but the possibility
should be alluded to.
3. Color images may be preferable especially in the pathology and endoscopy
images!
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
No conflict of interest
Please review this paper.
user
Reviewer's report
Title:Intraductal papillary mucinous carcinoma of the pancreas associated with
pancreas divisum: a case report and review of the literature
Version:3Date:21 April 2015
Reviewer: Puneet Dhar
Reviewer's report:
Interesting case report of a combination of IPMN occurring with pancreas
divisum. Other published cases reporting this combination have also been
reviewed. The difference here is the presentation in the ventral anlage of
pancreas.
Discretionary Revisions:
1. There is a significant overlap of reviewed cases with a previous publication
from Italy (Zippi and Quarto, J Gastroint Dig Syst 2014, 4:171 available online at
http://dx.doi.org/10.4172/2161-069X.1000171). The current submission has 12 of
the cases in Table 1 mentioned in a table in the earlier publication (omitting 1). It
may be preferable to allude to this publication and tabulate only the 2 fresh cases
added in this submission.
2. The diagnosis of Pancreas divisum has been established in the reported case
by ERCP . However since there is a coexistent tumour (IPMN here, it is possible
that it is incomplete divisum and the connection with main pancreatic duct has
been obscured by tumour obstruction. It may not be the case - but the possibility
should be alluded to.
3. Color images may be preferable especially in the pathology and endoscopy
images!
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests:
No conflict of interest
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