Reviewer's report
Title:Five mucosal transcripts of interest in ulcerative colitis identified by
quantitative real-time PCR: a prospective study
Version: 2Date:16 November 2007
Reviewer: alexandra zahn
Reviewer's report:
General
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Major Compulsory Revisions (that the author must respond to before a decision
on publication can be reached)
In my opinion, the major problem of this study persists after revision. No
additional experiments on protein level were performed. Thus, the impact of the
authors findings on the pathophysiology of UC stays unclear. This is reflected in
a very speculative discussion. I cannot recommend the manuscript for
publication.
-------------------------------------------------------------------------------
Minor Essential Revisions (such as missing labels on figures, or the wrong use of
a term, which the author can be trusted to correct)
-------------------------------------------------------------------------------
Discretionary Revisions (which the author can choose to ignore)
What next?: Reject because too small an advance to publish
Level of interest: An article of limited interest
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests.
Reviewer's report
Title:Five mucosal transcripts of interest in ulcerative colitis identified by
quantitative real-time PCR: a prospective study
Version: 2Date:16 November 2007
Reviewer: alexandra zahn
Reviewer's report:
General
-------------------------------------------------------------------------------
Major Compulsory Revisions (that the author must respond to before a decision
on publication can be reached)
In my opinion, the major problem of this study persists after revision. No
additional experiments on protein level were performed. Thus, the impact of the
authors findings on the pathophysiology of UC stays unclear. This is reflected in
a very speculative discussion. I cannot recommend the manuscript for
publication.
-------------------------------------------------------------------------------
Minor Essential Revisions (such as missing labels on figures, or the wrong use of
a term, which the author can be trusted to correct)
-------------------------------------------------------------------------------
Discretionary Revisions (which the author can choose to ignore)
What next?: Reject because too small an advance to publish
Level of interest: An article of limited interest
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests.
Please review this paper.
user
Reviewer's report
Title:Five mucosal transcripts of interest in ulcerative colitis identified by
quantitative real-time PCR: a prospective study
Version: 2Date:16 November 2007
Reviewer: alexandra zahn
Reviewer's report:
General
-------------------------------------------------------------------------------
Major Compulsory Revisions (that the author must respond to before a decision
on publication can be reached)
In my opinion, the major problem of this study persists after revision. No
additional experiments on protein level were performed. Thus, the impact of the
authors findings on the pathophysiology of UC stays unclear. This is reflected in
a very speculative discussion. I cannot recommend the manuscript for
publication.
-------------------------------------------------------------------------------
Minor Essential Revisions (such as missing labels on figures, or the wrong use of
a term, which the author can be trusted to correct)
-------------------------------------------------------------------------------
Discretionary Revisions (which the author can choose to ignore)
What next?: Reject because too small an advance to publish
Level of interest: An article of limited interest
Quality of written English: Acceptable
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests.
assistant