Title: Prognostic Value of Neutrophil-to-Lymphocyte Ratio in Septic Patients with Liver
Cirrhosis: A Cohort Study
Version: 1 Date: 27 May 2025
Reviewer's report:
Thank you for revising the manuscript and addressing most of the concerns raised in the initial
review. The authors have made significant improvements to the methodology, data analysis,
and presentation of results, which substantially enhance the quality of the work. However, two
issues still require further revision to ensure the scientific rigor and validity of the conclusions.
1. Concern Regarding the process of identifying cirrhosis patients from the sepsis cohort .
While the authors have provided the detailed process in the response letter, the revised
manuscript still does not add it. Please add the  process  in the revised manuscript.
2. Concern Regarding the issue of Model I
The authors declaimed that they haved incorporated MELD scores and a composite indicator
for severe liver disease as covariates in the Model I  in the revised Table 2. However, However,
I did not find any modifications in Notes of Table 2.
Title: Prognostic Value of Neutrophil-to-Lymphocyte Ratio in Septic Patients with Liver
Cirrhosis: A Cohort Study
Version: 1 Date: 27 May 2025
Reviewer's report:
Thank you for revising the manuscript and addressing most of the concerns raised in the initial
review. The authors have made significant improvements to the methodology, data analysis,
and presentation of results, which substantially enhance the quality of the work. However, two
issues still require further revision to ensure the scientific rigor and validity of the conclusions.
1. Concern Regarding the process of identifying cirrhosis patients from the sepsis cohort .
While the authors have provided the detailed process in the response letter, the revised
manuscript still does not add it. Please add the  process  in the revised manuscript.
2. Concern Regarding the issue of Model I
The authors declaimed that they haved incorporated MELD scores and a composite indicator
for severe liver disease as covariates in the Model I  in the revised Table 2. However, However,
I did not find any modifications in Notes of Table 2.
Please review this paper.
user
Title: Prognostic Value of Neutrophil-to-Lymphocyte Ratio in Septic Patients with Liver
Cirrhosis: A Cohort Study
Version: 1 Date: 27 May 2025
Reviewer's report:
Thank you for revising the manuscript and addressing most of the concerns raised in the initial
review. The authors have made significant improvements to the methodology, data analysis,
and presentation of results, which substantially enhance the quality of the work. However, two
issues still require further revision to ensure the scientific rigor and validity of the conclusions.
1. Concern Regarding the process of identifying cirrhosis patients from the sepsis cohort .
While the authors have provided the detailed process in the response letter, the revised
manuscript still does not add it. Please add the  process  in the revised manuscript.
2. Concern Regarding the issue of Model I
The authors declaimed that they haved incorporated MELD scores and a composite indicator
for severe liver disease as covariates in the Model I  in the revised Table 2. However, However,
I did not find any modifications in Notes of Table 2.
assistant