Title: Multicenter analysis of the efficacy of early cholecystectomy and preoperative
cholecystostomy for severe acute cholecystitis: A retrospective study of data from the multi-
institutional database of the Hiroshima Surgical Study Group of Clinical Oncology
Version: 6 Date: 08 Sep 2024
Reviewer's report:
The manuscript presents a comprehensive and well-structured retrospective study evaluating
the timing and effectiveness of early cholecystectomy and preoperative percutaneous
cholecystostomy (PC) for patients with severe acute cholecystitis. The study provides valuable
insights into the optimal treatment strategies for high-risk patients, and the data derived from
a multi-institutional database strengthens the reliability of the findings. Overall, the manuscript
is well-written, and the research methodology is sound. The statistical analyses are appropriate,
and the conclusions are well-supported by the data.I recommend the manuscript for publication
Title: Multicenter analysis of the efficacy of early cholecystectomy and preoperative
cholecystostomy for severe acute cholecystitis: A retrospective study of data from the multi-
institutional database of the Hiroshima Surgical Study Group of Clinical Oncology
Version: 6 Date: 08 Sep 2024
Reviewer's report:
The manuscript presents a comprehensive and well-structured retrospective study evaluating
the timing and effectiveness of early cholecystectomy and preoperative percutaneous
cholecystostomy (PC) for patients with severe acute cholecystitis. The study provides valuable
insights into the optimal treatment strategies for high-risk patients, and the data derived from
a multi-institutional database strengthens the reliability of the findings. Overall, the manuscript
is well-written, and the research methodology is sound. The statistical analyses are appropriate,
and the conclusions are well-supported by the data.I recommend the manuscript for publication
Please review this paper.
user
Title: Multicenter analysis of the efficacy of early cholecystectomy and preoperative
cholecystostomy for severe acute cholecystitis: A retrospective study of data from the multi-
institutional database of the Hiroshima Surgical Study Group of Clinical Oncology
Version: 6 Date: 08 Sep 2024
Reviewer's report:
The manuscript presents a comprehensive and well-structured retrospective study evaluating
the timing and effectiveness of early cholecystectomy and preoperative percutaneous
cholecystostomy (PC) for patients with severe acute cholecystitis. The study provides valuable
insights into the optimal treatment strategies for high-risk patients, and the data derived from
a multi-institutional database strengthens the reliability of the findings. Overall, the manuscript
is well-written, and the research methodology is sound. The statistical analyses are appropriate,
and the conclusions are well-supported by the data.I recommend the manuscript for publication
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