Reviewer's report
Title:Bleeding from gastrointestinal angioectasias is not related to bleeding
disorders - a case control study
Version: 1Date:1 February 2010
Reviewer: Meganathan Kannan
Reviewer's report:
Thanks for sending the manuscript for review and my comments are as follows;
1. The aim of the study was reasonable and the primary goal of the study was to
correlate the “bleeding from angioectasis” with the “bleeding disorder”.
2. While the platelet count was normal, that may exclude the possibility of
thrombocytopenia related bleeding; did the authors perform any of the platelet
function studies? Because the platelet dysfunction can cause bleeding.
3. What was the severity of bleeding in the study group? The severity may be
evaluated based on the number of transfusion required (single or multiple) to
stop the bleeding.
4. To have a meaningful statistical comparison, the control group could have
been increased to minimum of fifty.
5. The discussion needs to be re-written.
6. Recent references in the relevant field need to be cited. For example there are
several reports on AVWS and Bleeding disorders.
The manuscript may be accepted after the modification.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests.
Reviewer's report
Title:Bleeding from gastrointestinal angioectasias is not related to bleeding
disorders - a case control study
Version: 1Date:1 February 2010
Reviewer: Meganathan Kannan
Reviewer's report:
Thanks for sending the manuscript for review and my comments are as follows;
1. The aim of the study was reasonable and the primary goal of the study was to
correlate the “bleeding from angioectasis” with the “bleeding disorder”.
2. While the platelet count was normal, that may exclude the possibility of
thrombocytopenia related bleeding; did the authors perform any of the platelet
function studies? Because the platelet dysfunction can cause bleeding.
3. What was the severity of bleeding in the study group? The severity may be
evaluated based on the number of transfusion required (single or multiple) to
stop the bleeding.
4. To have a meaningful statistical comparison, the control group could have
been increased to minimum of fifty.
5. The discussion needs to be re-written.
6. Recent references in the relevant field need to be cited. For example there are
several reports on AVWS and Bleeding disorders.
The manuscript may be accepted after the modification.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests.
Please review this paper.
user
Reviewer's report
Title:Bleeding from gastrointestinal angioectasias is not related to bleeding
disorders - a case control study
Version: 1Date:1 February 2010
Reviewer: Meganathan Kannan
Reviewer's report:
Thanks for sending the manuscript for review and my comments are as follows;
1. The aim of the study was reasonable and the primary goal of the study was to
correlate the “bleeding from angioectasis” with the “bleeding disorder”.
2. While the platelet count was normal, that may exclude the possibility of
thrombocytopenia related bleeding; did the authors perform any of the platelet
function studies? Because the platelet dysfunction can cause bleeding.
3. What was the severity of bleeding in the study group? The severity may be
evaluated based on the number of transfusion required (single or multiple) to
stop the bleeding.
4. To have a meaningful statistical comparison, the control group could have
been increased to minimum of fifty.
5. The discussion needs to be re-written.
6. Recent references in the relevant field need to be cited. For example there are
several reports on AVWS and Bleeding disorders.
The manuscript may be accepted after the modification.
Level of interest: An article whose findings are important to those with closely
related research interests
Quality of written English: Needs some language corrections before being
published
Statistical review: No, the manuscript does not need to be seen by a
statistician.
Declaration of competing interests:
I declare that I have no competing interests.
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