Title: Awareness and treatment of Chronic Hepatitis B in Malaysia- findings from a community-
based screening campaign
Version: 1 Date: 21 Mar 2022
Reviewer's report:
This is a straightforward study highlighting a very important gap in the care cascade of hepatitis
B in Malaysia. Kudos to the authors!
That being said, there are some suggested edits that would strengthen this manuscript:
Abstract - HBV is an abbreviation for Hepatitis B Virus, so it is important to include that word
here.
Results – Their prevalence date suggests only a 2% positivity rate, that is surprising. I thought
it would be higher! Does this prevalence reflect the overall prevalence in Malaysia? It would be
good to address this in a sentence or two in the discussion section.
It would be a good addition to add a table to go along with these results, or a figure describing
the care cascade, with these numbers.
You mention standard deviation and confidence intervals in the abbreviations below. Did you
do any data analysis to look for correlates of infection awareness and antiviral treatment – if you
did, it would be good to describe those methods in the methods section and those results here
(with significance, p-values, confidence intervals). It would be very helpful to know who was
more likely to be aware of their infection (independent variables of age, gender, etc) and who
was more likely to be on antiviral treatment. If you didn’t do that level of analysis, that is fine,
but then you should remove those terms from the abbreviation list.
Discussion - Do the authors have knowledge of where the biggest gaps are, and what strategies
could help improve the cascade? What would be the next step(s) that the authors suggest in order
to improve the current situation? A few concrete steps would be an important call to action for
researchers, advocates and decision makers.
Abbreviations –
The term “confidence interval” is not found in the manuscript.
The term “Non-Governmental Organizations” is not found in the manuscript.
The term “point of care tests” is not found in the manuscript.
The term “standard deviation” is not found in the manuscript.
Title: Awareness and treatment of Chronic Hepatitis B in Malaysia- findings from a community-
based screening campaign
Version: 1 Date: 21 Mar 2022
Reviewer's report:
This is a straightforward study highlighting a very important gap in the care cascade of hepatitis
B in Malaysia. Kudos to the authors!
That being said, there are some suggested edits that would strengthen this manuscript:
Abstract - HBV is an abbreviation for Hepatitis B Virus, so it is important to include that word
here.
Results – Their prevalence date suggests only a 2% positivity rate, that is surprising. I thought
it would be higher! Does this prevalence reflect the overall prevalence in Malaysia? It would be
good to address this in a sentence or two in the discussion section.
It would be a good addition to add a table to go along with these results, or a figure describing
the care cascade, with these numbers.
You mention standard deviation and confidence intervals in the abbreviations below. Did you
do any data analysis to look for correlates of infection awareness and antiviral treatment – if you
did, it would be good to describe those methods in the methods section and those results here
(with significance, p-values, confidence intervals). It would be very helpful to know who was
more likely to be aware of their infection (independent variables of age, gender, etc) and who
was more likely to be on antiviral treatment. If you didn’t do that level of analysis, that is fine,
but then you should remove those terms from the abbreviation list.
Discussion - Do the authors have knowledge of where the biggest gaps are, and what strategies
could help improve the cascade? What would be the next step(s) that the authors suggest in order
to improve the current situation? A few concrete steps would be an important call to action for
researchers, advocates and decision makers.
Abbreviations –
The term “confidence interval” is not found in the manuscript.
The term “Non-Governmental Organizations” is not found in the manuscript.
The term “point of care tests” is not found in the manuscript.
The term “standard deviation” is not found in the manuscript.
Please review this paper.
user
Title: Awareness and treatment of Chronic Hepatitis B in Malaysia- findings from a community-
based screening campaign
Version: 1 Date: 21 Mar 2022
Reviewer's report:
This is a straightforward study highlighting a very important gap in the care cascade of hepatitis
B in Malaysia. Kudos to the authors!
That being said, there are some suggested edits that would strengthen this manuscript:
Abstract - HBV is an abbreviation for Hepatitis B Virus, so it is important to include that word
here.
Results – Their prevalence date suggests only a 2% positivity rate, that is surprising. I thought
it would be higher! Does this prevalence reflect the overall prevalence in Malaysia? It would be
good to address this in a sentence or two in the discussion section.
It would be a good addition to add a table to go along with these results, or a figure describing
the care cascade, with these numbers.
You mention standard deviation and confidence intervals in the abbreviations below. Did you
do any data analysis to look for correlates of infection awareness and antiviral treatment – if you
did, it would be good to describe those methods in the methods section and those results here
(with significance, p-values, confidence intervals). It would be very helpful to know who was
more likely to be aware of their infection (independent variables of age, gender, etc) and who
was more likely to be on antiviral treatment. If you didn’t do that level of analysis, that is fine,
but then you should remove those terms from the abbreviation list.
Discussion - Do the authors have knowledge of where the biggest gaps are, and what strategies
could help improve the cascade? What would be the next step(s) that the authors suggest in order
to improve the current situation? A few concrete steps would be an important call to action for
researchers, advocates and decision makers.
Abbreviations –
The term “confidence interval” is not found in the manuscript.
The term “Non-Governmental Organizations” is not found in the manuscript.
The term “point of care tests” is not found in the manuscript.
The term “standard deviation” is not found in the manuscript.
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