Title: Fecal calprotectin is a useful biomarker for predicting the clinical outcome of granulocyte
and monocyte adsorptive apheresis in ulcerative colitis patients: a prospective observation study.
Version: 2 Date: 02 Apr 2021
Reviewer's report:
Dear authors
I am interested in this manuscript. Although the eligible patients were a few, you indicated and
demonstrated that fecal calprotectine (FC) the predictive biomarker of good clinical response to
GMA and improvement of mucosal inflammation after GMA treatment. Recently it is not easy
to undergo colonoscopy  for patients, because the spread of COVID19 is getting to be pretty
serious. So we suggested that the utility of FC will be enhanced. We think that this report are
very useful for treatment of ulcerative colitis.
Title: Fecal calprotectin is a useful biomarker for predicting the clinical outcome of granulocyte
and monocyte adsorptive apheresis in ulcerative colitis patients: a prospective observation study.
Version: 2 Date: 02 Apr 2021
Reviewer's report:
Dear authors
I am interested in this manuscript. Although the eligible patients were a few, you indicated and
demonstrated that fecal calprotectine (FC) the predictive biomarker of good clinical response to
GMA and improvement of mucosal inflammation after GMA treatment. Recently it is not easy
to undergo colonoscopy  for patients, because the spread of COVID19 is getting to be pretty
serious. So we suggested that the utility of FC will be enhanced. We think that this report are
very useful for treatment of ulcerative colitis.
Please review this paper.
user
Title: Fecal calprotectin is a useful biomarker for predicting the clinical outcome of granulocyte
and monocyte adsorptive apheresis in ulcerative colitis patients: a prospective observation study.
Version: 2 Date: 02 Apr 2021
Reviewer's report:
Dear authors
I am interested in this manuscript. Although the eligible patients were a few, you indicated and
demonstrated that fecal calprotectine (FC) the predictive biomarker of good clinical response to
GMA and improvement of mucosal inflammation after GMA treatment. Recently it is not easy
to undergo colonoscopy  for patients, because the spread of COVID19 is getting to be pretty
serious. So we suggested that the utility of FC will be enhanced. We think that this report are
very useful for treatment of ulcerative colitis.
assistant