Title: Noninvasive models for the prediction of liver fibrosis in patients with chronic hepatitis B
Version: 0 Date: 20 Nov 2023
Reviewer:  Jean-Pierre Zarski
Reviewer's report:
This study, involving a large number of patients, investigated the value of several simple
biological tests for the assessment of fibrosis in chronic hepatitis B. These tests have no patent.
They were compared with liver biopsy.
1) What is the delay between biopsy and blood testing?
2) Has the biopsy been independently reviewed by one or more ana pathologists?
3) Is a study of cirrhotic patients alone with AUROCs (F4) missing?
4) Have you performed or compared elastometry (fibroscan)? or other frequently used blood
tests? Fibotest, Fibrometer, Hepascore?
Title: Noninvasive models for the prediction of liver fibrosis in patients with chronic hepatitis B
Version: 0 Date: 20 Nov 2023
Reviewer:  Jean-Pierre Zarski
Reviewer's report:
This study, involving a large number of patients, investigated the value of several simple
biological tests for the assessment of fibrosis in chronic hepatitis B. These tests have no patent.
They were compared with liver biopsy.
1) What is the delay between biopsy and blood testing?
2) Has the biopsy been independently reviewed by one or more ana pathologists?
3) Is a study of cirrhotic patients alone with AUROCs (F4) missing?
4) Have you performed or compared elastometry (fibroscan)? or other frequently used blood
tests? Fibotest, Fibrometer, Hepascore?
Please review this paper.
user
Title: Noninvasive models for the prediction of liver fibrosis in patients with chronic hepatitis B
Version: 0 Date: 20 Nov 2023
Reviewer:  Jean-Pierre Zarski
Reviewer's report:
This study, involving a large number of patients, investigated the value of several simple
biological tests for the assessment of fibrosis in chronic hepatitis B. These tests have no patent.
They were compared with liver biopsy.
1) What is the delay between biopsy and blood testing?
2) Has the biopsy been independently reviewed by one or more ana pathologists?
3) Is a study of cirrhotic patients alone with AUROCs (F4) missing?
4) Have you performed or compared elastometry (fibroscan)? or other frequently used blood
tests? Fibotest, Fibrometer, Hepascore?
assistant