Title: Choledocholithiasis as a risk factor for cholangiocarcinoma: a nationwide retrospective
cohort study
Version: 2 Date: 13 Jan 2025
Reviewer:  Cecilia Stromberg
Reviewer's report:
This is a well performed  study and  a well written  manuscript  well in agreement with previous
findings.
1. How accurate is the diagnosis of bile duct stones in the databases you have used? Has the
databases been validated ?
2. How were the stones treated? Did all patients have an ERCP ?  How many had
sphincterotomy?  Open surgery? Do these groups differ regarding risk of ECC  or ICC?
Title: Choledocholithiasis as a risk factor for cholangiocarcinoma: a nationwide retrospective
cohort study
Version: 2 Date: 13 Jan 2025
Reviewer:  Cecilia Stromberg
Reviewer's report:
This is a well performed  study and  a well written  manuscript  well in agreement with previous
findings.
1. How accurate is the diagnosis of bile duct stones in the databases you have used? Has the
databases been validated ?
2. How were the stones treated? Did all patients have an ERCP ?  How many had
sphincterotomy?  Open surgery? Do these groups differ regarding risk of ECC  or ICC?
Please review this paper.
user
Title: Choledocholithiasis as a risk factor for cholangiocarcinoma: a nationwide retrospective
cohort study
Version: 2 Date: 13 Jan 2025
Reviewer:  Cecilia Stromberg
Reviewer's report:
This is a well performed  study and  a well written  manuscript  well in agreement with previous
findings.
1. How accurate is the diagnosis of bile duct stones in the databases you have used? Has the
databases been validated ?
2. How were the stones treated? Did all patients have an ERCP ?  How many had
sphincterotomy?  Open surgery? Do these groups differ regarding risk of ECC  or ICC?
assistant