Title: Prevalence and factors associated with fatigue in patients with ulcerative colitis in China:
A cross-sectional study
Version: 1 Date: 05 Feb 2022
Reviewer:  Katsuhisa Ohashi
Reviewer's report:
Fatigue symptoms are difficult to recognize in clinical practice and often underestimated
compared to patient complaints. It is significant to show that patients with ulcerative colitis who
have various disabilities in their daily lives often have complications of fatigue, even when they
are in remission. In addition to the disease status of ulcerative colitis, such as the extent of colitis
and disease activity, psychological factors such as anxiety are also associated with an increased
risk of fatigue, and thus the need for comprehensive care is recognized. The study is statistically
well designed and should be evaluated in a larger number of patients in the future.
Title: Prevalence and factors associated with fatigue in patients with ulcerative colitis in China:
A cross-sectional study
Version: 1 Date: 05 Feb 2022
Reviewer:  Katsuhisa Ohashi
Reviewer's report:
Fatigue symptoms are difficult to recognize in clinical practice and often underestimated
compared to patient complaints. It is significant to show that patients with ulcerative colitis who
have various disabilities in their daily lives often have complications of fatigue, even when they
are in remission. In addition to the disease status of ulcerative colitis, such as the extent of colitis
and disease activity, psychological factors such as anxiety are also associated with an increased
risk of fatigue, and thus the need for comprehensive care is recognized. The study is statistically
well designed and should be evaluated in a larger number of patients in the future.
Please review this paper.
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Title: Prevalence and factors associated with fatigue in patients with ulcerative colitis in China:
A cross-sectional study
Version: 1 Date: 05 Feb 2022
Reviewer:  Katsuhisa Ohashi
Reviewer's report:
Fatigue symptoms are difficult to recognize in clinical practice and often underestimated
compared to patient complaints. It is significant to show that patients with ulcerative colitis who
have various disabilities in their daily lives often have complications of fatigue, even when they
are in remission. In addition to the disease status of ulcerative colitis, such as the extent of colitis
and disease activity, psychological factors such as anxiety are also associated with an increased
risk of fatigue, and thus the need for comprehensive care is recognized. The study is statistically
well designed and should be evaluated in a larger number of patients in the future.
assistant