abetalipoproteinemia: a rare inherited disorder of fat metabolism; characterized by severe deficiency of beta-lipoproteins and abnormal red blood cells (acanthocytes) and abnormally low cholesterol levels
hypobetalipoproteinemia: a hereditary disorder characterized by low levels of beta-lipoproteins and lipids and cholesterol
alteration: the act of making something different (as e.g. the size of a garment)