sifter: a household sieve (as for flour)
sieve: a strainer for separating lumps from powdered material or grading particles
charcot-marie-tooth disease: a form of neuropathy that can begin between childhood and young adulthood; characterized by weakness and atrophy of the muscles of the hands and lower legs; progression is slow and individuals affected can have a normal life span; inheritance is X-linked recessive or X-linked dominant