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ADNI_033_S_5259_MR_MPRAGE_br_raw_20130726063429819_52_S196570_I382634
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- temporal lobe appears preserved, with no observable tissue loss
- no evident atrophy or tissue thinning seen in the occipital lobe
- limbic cortex demonstrates a healthy morphology without signs of atrophy
- insular cortex maintains a normal appearance with no observable atrophic features
- no findings suggestive of atrophy are seen in the parietal lobe
- frontal lobe appears preserved, with no observable tissue loss
For the ventricles:
- 4th ventricle appears within normal size limits with no apparent enlargement
- no observable enlargement of the 3rd ventricle
- inf. lateral ventricle appears within normal size limits with no apparent enlargement
- no evident size increase noted in the external csf
- no appreciable enlargement noted in the lateral ventricle
For the subcortical structures:
- no findings suggestive of atrophy are seen in the hippocampus
- mild bilateral atrophy of the basal forebrain
- no observable atrophic changes in the ventral dc
- no observable atrophic changes in the putamen
- no findings suggestive of atrophy are seen in the thalamus
- amygdala appears within normal limits without apparent atrophy
- pallidum appears preserved, with no observable tissue loss
- no observable atrophic changes in the caudate
- the accumbens shows no notable changes suggestive of atrophy
|
CN
|
FTLD_203673010_03017_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178325_dupl_7
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- moderate-to-severe enlargement of the external csf
- mild-to-moderate enlargement of the 3rd ventricle
- 4th ventricle maintains a typical volume without observable enlargement
- severe bilateral enlargement of the lateral ventricle
- mild-to-moderate bilateral enlargement of the inf. lateral ventricle
For the subcortical structures:
- the basal forebrain shows no notable changes suggestive of atrophy
- moderate atrophy of the left thalamus and mild-to-moderate atrophy of the right thalamus
- moderate atrophy of the left accumbens and mild-to-moderate atrophy of the right accumbens
- mild-to-moderate atrophy of the left hippocampus
- the left hippocampus volume is borderline low
- moderate atrophy of the left caudate and moderate-to-severe atrophy of the right caudate
- mild atrophy of the left amygdala and mild-to-moderate atrophy of the right amygdala
- moderate atrophy of the left pallidum and moderate-to-severe atrophy of the right pallidum
- mild bilateral atrophy of the ventral dc
- moderate-to-severe bilateral atrophy of the putamen
For the cerebral cortex:
- no findings suggestive of atrophy are seen in the limbic cortex
- no appreciable degenerative or atrophic changes observed in the occipital lobe
- no appreciable degenerative or atrophic changes observed in the parietal lobe
- insular cortex demonstrates a healthy morphology without signs of atrophy
- moderate atrophy of the left frontal lobe and moderate-to-severe atrophy of the right frontal lobe; focal volume loss observed in the following subregions: middle frontal gyrus (mild-to-moderate atrophy on the left and moderate atrophy on the right), triangular inf. frontal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), lateral orbital gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), posterior orbital gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), supplementary motor cortex (mild atrophy both left/right), frontal pole (normal-to-mild atrophy on the left and mild atrophy on the right), anterior orbital gyrus (normal on the left and mild-to-moderate atrophy on the right), precentral gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), subcallosal area (no significant abnormality), sup. frontal gyrus medial segment (normal-to-mild atrophy on the left and mild atrophy on the right), gyrus rectus (no significant abnormality), medial frontal cortex (no significant abnormality), precentral gyrus medial segment (no significant abnormality), sup. frontal gyrus (no significant abnormality), orbital inf. frontal gyrus (no significant abnormality), opercular inf. frontal gyrus (no significant abnormality) and medial orbital gyrus (no significant abnormality)
- temporal lobe appears preserved, with no observable tissue loss
|
BV
|
FTLD_203142083_03384_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10450647_dupl_2
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- moderate atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: inf. temporal gyrus (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right), temporal pole (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), sup. temporal gyrus (no significant abnormality), fusiform gyrus (mild atrophy on the left), planum temporale (no significant abnormality), middle temporal gyrus (no significant abnormality), planum polare (no significant abnormality) and transverse temporal gyrus (no significant abnormality)
- the frontal lobe shows no notable changes suggestive of atrophy
- no findings suggestive of atrophy are seen in the limbic cortex
- no appreciable degenerative or atrophic changes observed in the parietal lobe
- occipital lobe maintains a normal appearance with no observable atrophic features
- insular cortex appears preserved, with no observable tissue loss
For the subcortical structures:
- no appreciable degenerative or atrophic changes observed in the thalamus
- ventral dc demonstrates a healthy morphology without signs of atrophy
- pallidum appears within normal limits without apparent atrophy
- mild atrophy of the left hippocampus
- moderate atrophy of the left amygdala; the right amygdala is normal
- no observable atrophic changes in the basal forebrain
- caudate demonstrates a healthy morphology without signs of atrophy
- no evident atrophy or tissue thinning seen in the putamen
- no evident atrophy or tissue thinning seen in the accumbens
For the ventricles:
- severe enlargement of the left inf. lateral ventricle; the right inf. lateral ventricle is normal
- no observable enlargement of the lateral ventricle
- mild enlargement of the 3rd ventricle
- no findings suggestive of enlargement are seen in the external csf
- no appreciable enlargement noted in the 4th ventricle
|
SV
|
FTLD_203390564_03469_MR_Accelerated_Sagittal_IR-FSPGR_br_raw_202_I10450804
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- no clear enlargement or abnormal growth seen in the lateral ventricle
- 3rd ventricle appears to be of normal dimensions, with no observable increase in size
- the 4th ventricle shows no notable changes suggestive of enlargement
- external csf appears to be of normal dimensions, with no observable increase in size
- no findings suggestive of enlargement are seen in the inf. lateral ventricle
For the cerebral cortex:
- mild atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: parietal operculum (mild atrophy both left/right), posterior insula (mild-to-moderate atrophy on the left and normal on the right), anterior insula (no significant abnormality), central operculum (no significant abnormality) and frontal operculum (no significant abnormality)
- occipital lobe demonstrates a healthy morphology without signs of atrophy
- frontal lobe maintains a normal appearance with no observable atrophic features
- no evident atrophy or tissue thinning seen in the parietal lobe
- temporal lobe maintains a normal appearance with no observable atrophic features
- no appreciable degenerative or atrophic changes observed in the limbic cortex
For the subcortical structures:
- pallidum appears within normal limits without apparent atrophy
- caudate maintains a normal appearance with no observable atrophic features
- mild bilateral atrophy of the amygdala
- basal forebrain appears preserved, with no observable tissue loss
- thalamus appears preserved, with no observable tissue loss
- accumbens appears within normal limits without apparent atrophy
- ventral dc appears within normal limits without apparent atrophy
- no findings suggestive of atrophy are seen in the putamen
- mild atrophy of the left hippocampus
|
CN
|
FTLD_203177063_03367_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10450616_dupl_1
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- mild-to-moderate atrophy of the left frontal lobe; the right frontal lobe is normal; focal volume loss observed in the following subregions: subcallosal area (no significant abnormality), sup. frontal gyrus (mild atrophy on the left), opercular inf. frontal gyrus (mild-to-moderate atrophy on the left and normal on the right), posterior orbital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), precentral gyrus medial segment (no significant abnormality), sup. frontal gyrus medial segment (mild atrophy on the left and normal-to-mild atrophy on the right), frontal pole (mild atrophy on the left and normal on the right), medial frontal cortex (mild atrophy on the left and normal on the right), medial orbital gyrus (mild atrophy on the left and normal on the right), gyrus rectus (mild atrophy on the right), orbital inf. frontal gyrus (no significant abnormality), triangular inf. frontal gyrus (no significant abnormality), middle frontal gyrus (no significant abnormality), precentral gyrus (no significant abnormality), anterior orbital gyrus (no significant abnormality), lateral orbital gyrus (no significant abnormality) and supplementary motor cortex (no significant abnormality)
- mild-to-moderate atrophy of the left insular cortex and mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (severe atrophy on the left and moderate atrophy on the right), frontal operculum (mild-to-moderate atrophy on the left and mild atrophy on the right), posterior insula (no significant abnormality), central operculum (no significant abnormality) and parietal operculum (no significant abnormality)
- the parietal lobe shows no notable changes suggestive of atrophy
- occipital lobe appears within normal limits without apparent atrophy
- mild bilateral atrophy of the temporal lobe; focal volume loss observed in the following subregions: inf. temporal gyrus (mild atrophy both left/right), fusiform gyrus (no significant abnormality), planum polare (no significant abnormality), planum temporale (no significant abnormality), middle temporal gyrus (no significant abnormality), temporal pole (no significant abnormality), sup. temporal gyrus (no significant abnormality) and transverse temporal gyrus (no significant abnormality)
- limbic cortex appears preserved, with no observable tissue loss
For the ventricles:
- no evident size increase noted in the inf. lateral ventricle
- lateral ventricle maintains its expected proportions without signs of enlargement
- no evident size increase noted in the 4th ventricle
- mild enlargement of the external csf
- 3rd ventricle appears to be of normal dimensions, with no observable increase in size
For the subcortical structures:
- mild bilateral atrophy of the amygdala
- mild atrophy of the left putamen; the right putamen is normal
- no observable atrophic changes in the pallidum
- mild bilateral atrophy of the accumbens
- ventral dc appears preserved, with no observable tissue loss
- no appreciable degenerative or atrophic changes observed in the basal forebrain
- no findings suggestive of atrophy are seen in the hippocampus
- no observable atrophic changes in the thalamus
- mild atrophy of the left caudate; the right caudate is normal
|
PNFA
|
ADNI_126_S_5243_MR_Accelerated_Sag_IR-FSPGR___br_raw_20130716150308823_25_S195167_I380753
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- external csf maintains its expected proportions without signs of enlargement
- no appreciable enlargement noted in the 3rd ventricle
- no clear enlargement or abnormal growth seen in the lateral ventricle
- no appreciable enlargement noted in the 4th ventricle
- mild enlargement of the right inf. lateral ventricle; the left inf. lateral ventricle is normal
For the subcortical structures:
- no evident atrophy or tissue thinning seen in the thalamus
- hippocampus demonstrates a healthy morphology without signs of atrophy
- no evident atrophy or tissue thinning seen in the putamen
- no observable atrophic changes in the pallidum
- ventral dc demonstrates a healthy morphology without signs of atrophy
- no findings suggestive of atrophy are seen in the accumbens
- no evident atrophy or tissue thinning seen in the caudate
- no observable atrophic changes in the basal forebrain
- no observable atrophic changes in the amygdala
For the cerebral cortex:
- occipital lobe appears within normal limits without apparent atrophy
- no evident atrophy or tissue thinning seen in the parietal lobe
- no clear atrophic alterations are visible in the temporal lobe
- no observable atrophic changes in the frontal lobe
- insular cortex maintains a normal appearance with no observable atrophic features
- no observable atrophic changes in the limbic cortex
|
CN
|
FTLD_203605837_02730_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10449891_dupl_6
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- mild-to-moderate atrophy of the left caudate and severe atrophy of the right caudate
- moderate atrophy of the left accumbens and severe atrophy of the right accumbens
- mild-to-moderate atrophy of the left putamen and severe atrophy of the right putamen
- mild atrophy of the right thalamus; normal-to-mild atrophy of the left thalamus
- mild-to-moderate atrophy of the left amygdala and severe atrophy of the right amygdala
- ventral dc maintains a normal appearance with no observable atrophic features
- mild atrophy of the left pallidum and mild-to-moderate atrophy of the right pallidum
- no appreciable degenerative or atrophic changes observed in the basal forebrain
- mild atrophy of the left hippocampus
- mild-to-moderate atrophy of the right hippocampus
For the ventricles:
- severe bilateral enlargement of the inf. lateral ventricle
- mild enlargement of the 4th ventricle
- mild-to-moderate enlargement of the external csf
- moderate enlargement of the 3rd ventricle
- moderate enlargement of the left lateral ventricle and severe enlargement of the right lateral ventricle
For the cerebral cortex:
- moderate-to-severe atrophy of the left frontal lobe and severe atrophy of the right frontal lobe; focal volume loss observed in the following subregions: middle frontal gyrus (mild-to-moderate atrophy on the left and moderate-to-severe atrophy on the right), medial orbital gyrus (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right), sup. frontal gyrus medial segment (mild atrophy on the left and moderate-to-severe atrophy on the right), gyrus rectus (mild-to-moderate atrophy both left/right), sup. frontal gyrus (mild-to-moderate atrophy both left/right), lateral orbital gyrus (normal-to-mild atrophy on the left and moderate atrophy on the right), frontal pole (mild atrophy on the left and mild-to-moderate atrophy on the right), orbital inf. frontal gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), medial frontal cortex (mild atrophy both left/right), posterior orbital gyrus (mild atrophy both left/right), anterior orbital gyrus (normal on the left and moderate atrophy on the right), opercular inf. frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), precentral gyrus medial segment (no significant abnormality), supplementary motor cortex (no significant abnormality), precentral gyrus (no significant abnormality), triangular inf. frontal gyrus (no significant abnormality) and subcallosal area (no significant abnormality)
- parietal lobe maintains a normal appearance with no observable atrophic features
- mild-to-moderate bilateral atrophy of the insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate atrophy on the left and moderate-to-severe atrophy on the right), frontal operculum (mild atrophy both left/right), central operculum (normal-to-mild atrophy on the left and mild atrophy on the right), posterior insula (normal-to-mild atrophy on the left and mild atrophy on the right) and parietal operculum (no significant abnormality)
- no findings suggestive of atrophy are seen in the occipital lobe
- moderate bilateral atrophy of the limbic cortex; focal volume loss observed in the following subregions: anterior cingulate gyrus (moderate atrophy both left/right), middle cingulate gyrus (mild-to-moderate atrophy both left/right), entorhinal area (mild atrophy on the right), parahippocampal gyrus (no significant abnormality) and posterior cingulate gyrus (no significant abnormality)
- mild atrophy of the right temporal lobe; the left temporal lobe is normal; focal volume loss observed in the following subregions: planum temporale (no significant abnormality), temporal pole (no significant abnormality), middle temporal gyrus (mild-to-moderate atrophy on the right), fusiform gyrus (no significant abnormality), sup. temporal gyrus (no significant abnormality), inf. temporal gyrus (no significant abnormality), transverse temporal gyrus (no significant abnormality) and planum polare (no significant abnormality)
|
BV
|
FTLD_203936524_01423_MR_Sagittal_MP-Rage_br_raw_20230206172842682_I10182092_dupl_1
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- the limbic cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in entorhinal area (mild-to-moderate atrophy on the left and moderate-to-severe atrophy on the right), posterior cingulate gyrus (no significant abnormality), parahippocampal gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), anterior cingulate gyrus (no significant abnormality) and middle cingulate gyrus (no significant abnormality)
- mild atrophy of the right parietal lobe; the left parietal lobe is normal; focal volume loss observed in the following subregions: postcentral gyrus medial segment (mild-to-moderate atrophy on the left), angular gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), postcentral gyrus (no significant abnormality), precuneus (no significant abnormality), supramarginal gyrus (no significant abnormality) and sup. parietal lobule (no significant abnormality)
- no appreciable degenerative or atrophic changes observed in the frontal lobe
- occipital lobe appears within normal limits without apparent atrophy
- mild-to-moderate atrophy of the right insular cortex; the left insular cortex is normal; focal volume loss observed in the following subregions: anterior insula (mild atrophy on the left and moderate-to-severe atrophy on the right), posterior insula (mild atrophy on the left and mild-to-moderate atrophy on the right), central operculum (mild atrophy on the right), parietal operculum (no significant abnormality) and frontal operculum (no significant abnormality)
- moderate atrophy of the left temporal lobe and severe atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (mild-to-moderate atrophy on the left and severe atrophy on the right), middle temporal gyrus (mild atrophy on the left and severe atrophy on the right), fusiform gyrus (mild-to-moderate atrophy on the left and moderate atrophy on the right), inf. temporal gyrus (normal on the left and moderate-to-severe atrophy on the right), planum polare (normal on the left and mild-to-moderate atrophy on the right), planum temporale (no significant abnormality), sup. temporal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and transverse temporal gyrus (no significant abnormality)
For the ventricles:
- severe bilateral enlargement of the inf. lateral ventricle
- moderate enlargement of the right lateral ventricle; normal-to-mild enlargement of the left lateral ventricle
- moderate enlargement of the 3rd ventricle
- no evident size increase noted in the 4th ventricle
- mild-to-moderate enlargement of the external csf
For the subcortical structures:
- mild-to-moderate atrophy of the right pallidum; the left pallidum is normal
- no observable atrophic changes in the basal forebrain
- ventral dc appears within normal limits without apparent atrophy
- mild-to-moderate atrophy of the left hippocampus
- severe atrophy of the right hippocampus
- severe bilateral atrophy of the amygdala
- mild-to-moderate atrophy of the left accumbens and severe atrophy of the right accumbens
- no appreciable degenerative or atrophic changes observed in the thalamus
- moderate-to-severe atrophy of the right putamen; normal-to-mild atrophy of the left putamen
- moderate atrophy of the right caudate; the left caudate is normal
|
SV
|
FTLD_203107266_02660_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177776_dupl_1
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- mild-to-moderate enlargement of the external csf
- mild enlargement of the left lateral ventricle; normal-to-mild enlargement of the right lateral ventricle
- 4th ventricle maintains its expected proportions without signs of enlargement
- mild-to-moderate enlargement of the 3rd ventricle
- severe enlargement of the left inf. lateral ventricle and moderate enlargement of the right inf. lateral ventricle
For the subcortical structures:
- thalamus maintains a normal appearance with no observable atrophic features
- caudate maintains a normal appearance with no observable atrophic features
- ventral dc appears preserved, with no observable tissue loss
- moderate atrophy of the left putamen; the right putamen is normal
- no appreciable degenerative or atrophic changes observed in the pallidum
- basal forebrain maintains a normal appearance with no observable atrophic features
- mild-to-moderate atrophy of the left accumbens; normal-to-mild atrophy of the right accumbens
- severe atrophy of the left amygdala and moderate-to-severe atrophy of the right amygdala
- moderate atrophy of the left hippocampus
For the cerebral cortex:
- no observable atrophic changes in the occipital lobe
- severe atrophy of the left temporal lobe and moderate atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (severe atrophy on the left and moderate atrophy on the right), sup. temporal gyrus (moderate-to-severe atrophy on the left and mild atrophy on the right), inf. temporal gyrus (mild-to-moderate atrophy both left/right), planum polare (moderate-to-severe atrophy on the left and normal on the right), fusiform gyrus (mild atrophy both left/right), middle temporal gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), planum temporale (mild-to-moderate atrophy on the left and normal on the right) and transverse temporal gyrus (mild atrophy on the left and normal on the right)
- no findings suggestive of atrophy are seen in the parietal lobe
- moderate-to-severe atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: entorhinal area (moderate-to-severe atrophy on the left and mild atrophy on the right), anterior cingulate gyrus (moderate atrophy on the left and normal-to-mild atrophy on the right), parahippocampal gyrus (moderate atrophy on the left and normal on the right), posterior cingulate gyrus (no significant abnormality) and middle cingulate gyrus (no significant abnormality)
- severe atrophy of the left insular cortex; normal-to-mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: posterior insula (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right), anterior insula (severe atrophy on the left and normal on the right), central operculum (mild atrophy on the left and normal-to-mild atrophy on the right), frontal operculum (mild-to-moderate atrophy on the left) and parietal operculum (mild atrophy on the left)
- no appreciable degenerative or atrophic changes observed in the frontal lobe
|
SV
|
FTLD_203107266_02660_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177776_dupl_10
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- severe atrophy of the left amygdala and moderate-to-severe atrophy of the right amygdala
- no findings suggestive of atrophy are seen in the basal forebrain
- no observable atrophic changes in the caudate
- pallidum maintains a normal appearance with no observable atrophic features
- moderate atrophy of the left hippocampus
- mild-to-moderate atrophy of the left accumbens; normal-to-mild atrophy of the right accumbens
- no observable atrophic changes in the ventral dc
- moderate atrophy of the left putamen; the right putamen is normal
- no findings suggestive of atrophy are seen in the thalamus
For the ventricles:
- severe enlargement of the left inf. lateral ventricle and moderate enlargement of the right inf. lateral ventricle
- mild-to-moderate enlargement of the external csf
- mild-to-moderate enlargement of the 3rd ventricle
- 4th ventricle maintains a typical volume without observable enlargement
- mild enlargement of the left lateral ventricle; normal-to-mild enlargement of the right lateral ventricle
For the cerebral cortex:
- moderate-to-severe atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: entorhinal area (moderate-to-severe atrophy on the left and mild atrophy on the right), anterior cingulate gyrus (moderate atrophy on the left and normal-to-mild atrophy on the right), parahippocampal gyrus (moderate atrophy on the left and normal on the right), posterior cingulate gyrus (no significant abnormality) and middle cingulate gyrus (no significant abnormality)
- parietal lobe demonstrates a healthy morphology without signs of atrophy
- severe atrophy of the left temporal lobe and moderate atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (severe atrophy on the left and moderate atrophy on the right), sup. temporal gyrus (moderate-to-severe atrophy on the left and mild atrophy on the right), inf. temporal gyrus (mild-to-moderate atrophy both left/right), planum polare (moderate-to-severe atrophy on the left and normal on the right), fusiform gyrus (mild atrophy both left/right), middle temporal gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), planum temporale (mild-to-moderate atrophy on the left and normal on the right) and transverse temporal gyrus (mild atrophy on the left and normal on the right)
- no observable atrophic changes in the frontal lobe
- severe atrophy of the left insular cortex; normal-to-mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: posterior insula (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right), anterior insula (severe atrophy on the left and normal on the right), central operculum (mild atrophy on the left and normal-to-mild atrophy on the right), frontal operculum (mild-to-moderate atrophy on the left) and parietal operculum (mild atrophy on the left)
- no clear atrophic alterations are visible in the occipital lobe
|
SV
|
ADNI_023_S_0331_MR_MPR__GradWarp__B1_Correction__N3__Scaled_Br_20090717141242912_S66021_I149510_dupl_2
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- mild-to-moderate atrophy of the left hippocampus
- moderate atrophy of the right hippocampus
- mild bilateral atrophy of the accumbens
- ventral dc appears within normal limits without apparent atrophy
- pallidum demonstrates a healthy morphology without signs of atrophy
- putamen appears preserved, with no observable tissue loss
- the basal forebrain shows no notable changes suggestive of atrophy
- mild bilateral atrophy of the amygdala
- thalamus appears within normal limits without apparent atrophy
- the caudate shows no notable changes suggestive of atrophy
For the ventricles:
- mild-to-moderate bilateral enlargement of the inf. lateral ventricle
- external csf appears within normal size limits with no apparent enlargement
- mild-to-moderate enlargement of the 4th ventricle
- 3rd ventricle maintains its expected proportions without signs of enlargement
- mild enlargement of the right lateral ventricle; normal-to-mild enlargement of the left lateral ventricle
For the cerebral cortex:
- mild atrophy of the left limbic cortex and mild-to-moderate atrophy of the right limbic cortex; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), middle cingulate gyrus (normal on the left and mild atrophy on the right), entorhinal area (no significant abnormality), posterior cingulate gyrus (mild atrophy on the left and normal on the right) and parahippocampal gyrus (no significant abnormality)
- frontal lobe maintains a normal appearance with no observable atrophic features
- mild atrophy of the right parietal lobe; the left parietal lobe is normal; focal volume loss observed in the following subregions: precuneus (mild atrophy both left/right), supramarginal gyrus (mild atrophy on the right), postcentral gyrus medial segment (no significant abnormality), angular gyrus (no significant abnormality), postcentral gyrus (no significant abnormality) and sup. parietal lobule (no significant abnormality)
- mild-to-moderate bilateral atrophy of the occipital lobe; focal volume loss observed in the following subregions: lingual gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), calcarine cortex (mild atrophy on the left and normal-to-mild atrophy on the right), cuneus (mild atrophy on the left and normal on the right), occipital fusiform gyrus (mild atrophy on the left), inf. occipital gyrus (no significant abnormality), middle occipital gyrus (no significant abnormality), occipital pole (no significant abnormality) and sup. occipital gyrus (no significant abnormality)
- insular cortex maintains a normal appearance with no observable atrophic features
- mild atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: temporal pole (mild atrophy on the left and normal-to-mild atrophy on the right), sup. temporal gyrus (no significant abnormality), fusiform gyrus (mild atrophy on the left), inf. temporal gyrus (no significant abnormality), planum polare (no significant abnormality), planum temporale (no significant abnormality), middle temporal gyrus (no significant abnormality) and transverse temporal gyrus (no significant abnormality)
|
AD
|
FTLD_203474892_02297_MR_Sagittal_MP-Rage_br_raw_20230209100618623_I10183355_dupl_7
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- ventral dc demonstrates a healthy morphology without signs of atrophy
- no appreciable degenerative or atrophic changes observed in the basal forebrain
- amygdala appears preserved, with no observable tissue loss
- mild bilateral atrophy of the caudate
- no findings suggestive of atrophy are seen in the hippocampus
- thalamus demonstrates a healthy morphology without signs of atrophy
- the putamen shows no notable changes suggestive of atrophy
- mild bilateral atrophy of the accumbens
- the pallidum shows no notable changes suggestive of atrophy
For the ventricles:
- mild enlargement of the 3rd ventricle
- mild-to-moderate enlargement of the external csf
- mild enlargement of the left inf. lateral ventricle; normal-to-mild enlargement of the right inf. lateral ventricle
- no findings suggestive of enlargement are seen in the 4th ventricle
- lateral ventricle maintains its expected proportions without signs of enlargement
For the cerebral cortex:
- no observable atrophic changes in the limbic cortex
- mild bilateral atrophy of the insular cortex; focal volume loss observed in the following subregions: anterior insula (mild atrophy both left/right), central operculum (mild atrophy both left/right), posterior insula (no significant abnormality), frontal operculum (no significant abnormality) and parietal operculum (no significant abnormality)
- parietal lobe maintains a normal appearance with no observable atrophic features
- mild atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: transverse temporal gyrus (normal on the left and mild atrophy on the right), planum polare (no significant abnormality), inf. temporal gyrus (mild atrophy on the left), temporal pole (mild atrophy on the left and normal on the right), fusiform gyrus (mild atrophy on the left), sup. temporal gyrus (no significant abnormality), planum temporale (no significant abnormality) and middle temporal gyrus (no significant abnormality)
- moderate bilateral atrophy of the frontal lobe; focal volume loss observed in the following subregions: precentral gyrus (mild-to-moderate atrophy both left/right), opercular inf. frontal gyrus (mild atrophy both left/right), triangular inf. frontal gyrus (mild atrophy both left/right), medial orbital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), sup. frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), supplementary motor cortex (mild atrophy on the left and normal-to-mild atrophy on the right), medial frontal cortex (mild atrophy on the left), orbital inf. frontal gyrus (no significant abnormality), posterior orbital gyrus (normal on the left and mild atrophy on the right), gyrus rectus (mild atrophy on the left and normal on the right), sup. frontal gyrus medial segment (mild atrophy on the right), middle frontal gyrus (no significant abnormality), lateral orbital gyrus (no significant abnormality), anterior orbital gyrus (no significant abnormality), subcallosal area (no significant abnormality), frontal pole (no significant abnormality) and precentral gyrus medial segment (no significant abnormality)
- occipital lobe appears within normal limits without apparent atrophy
|
PNFA
|
FTLD_203160043_01346_MR_Sagittal_MP-Rage_br_raw_20230206140338189_I10181124_dupl_14
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- accumbens maintains a normal appearance with no observable atrophic features
- putamen appears within normal limits without apparent atrophy
- no clear atrophic alterations are visible in the amygdala
- the left hippocampus volume is borderline low
- the left hippocampus volume is borderline low
- no evident atrophy or tissue thinning seen in the pallidum
- thalamus appears within normal limits without apparent atrophy
- mild atrophy of the right caudate; the left caudate is normal
- basal forebrain appears preserved, with no observable tissue loss
- no evident atrophy or tissue thinning seen in the ventral dc
For the cerebral cortex:
- no evident atrophy or tissue thinning seen in the insular cortex
- temporal lobe demonstrates a healthy morphology without signs of atrophy
- mild atrophy of the right frontal lobe; the left frontal lobe is normal; focal volume loss observed in the following subregions: precentral gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), sup. frontal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), middle frontal gyrus (no significant abnormality), subcallosal area (no significant abnormality), precentral gyrus medial segment (mild-to-moderate atrophy on the left), lateral orbital gyrus (no significant abnormality), opercular inf. frontal gyrus (no significant abnormality), medial orbital gyrus (no significant abnormality), triangular inf. frontal gyrus (no significant abnormality), medial frontal cortex (no significant abnormality), posterior orbital gyrus (no significant abnormality), gyrus rectus (no significant abnormality), supplementary motor cortex (no significant abnormality), frontal pole (no significant abnormality), orbital inf. frontal gyrus (no significant abnormality), anterior orbital gyrus (no significant abnormality) and sup. frontal gyrus medial segment (no significant abnormality)
- no findings suggestive of atrophy are seen in the limbic cortex
- no findings suggestive of atrophy are seen in the occipital lobe
- parietal lobe maintains a normal appearance with no observable atrophic features
For the ventricles:
- mild enlargement of the left lateral ventricle and moderate enlargement of the right lateral ventricle
- no appreciable enlargement noted in the 4th ventricle
- mild-to-moderate enlargement of the 3rd ventricle
- mild bilateral enlargement of the inf. lateral ventricle
- no evident size increase noted in the external csf
|
PNFA
|
FTLD_203432376_01673_MR_Sagittal_MP-Rage_br_raw_20230206145827122_I10181308_dupl_20
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- mild atrophy of the left pallidum and mild-to-moderate atrophy of the right pallidum
- mild-to-moderate atrophy of the left putamen and moderate atrophy of the right putamen
- mild atrophy of the right caudate; normal-to-mild atrophy of the left caudate
- no observable atrophic changes in the basal forebrain
- mild-to-moderate atrophy of the left accumbens and moderate atrophy of the right accumbens
- no findings suggestive of atrophy are seen in the hippocampus
- moderate bilateral atrophy of the amygdala
- the ventral dc shows no notable changes suggestive of atrophy
- thalamus appears within normal limits without apparent atrophy
For the ventricles:
- no observable enlargement of the 3rd ventricle
- moderate-to-severe enlargement of the external csf
- mild enlargement of the 4th ventricle
- no appreciable enlargement noted in the inf. lateral ventricle
- lateral ventricle maintains its expected proportions without signs of enlargement
For the cerebral cortex:
- mild atrophy of the left frontal lobe and moderate atrophy of the right frontal lobe; focal volume loss observed in the following subregions: frontal pole (mild atrophy on the left and moderate atrophy on the right), middle frontal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), lateral orbital gyrus (no significant abnormality), sup. frontal gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), triangular inf. frontal gyrus (no significant abnormality), medial frontal cortex (normal on the left and mild atrophy on the right), anterior orbital gyrus (normal on the left and mild atrophy on the right), orbital inf. frontal gyrus (no significant abnormality), precentral gyrus (normal on the left and mild atrophy on the right), supplementary motor cortex (no significant abnormality), precentral gyrus medial segment (no significant abnormality), opercular inf. frontal gyrus (no significant abnormality), sup. frontal gyrus medial segment (no significant abnormality), gyrus rectus (no significant abnormality), medial orbital gyrus (no significant abnormality), posterior orbital gyrus (no significant abnormality) and subcallosal area (no significant abnormality)
- mild atrophy of the left insular cortex and moderate atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (mild atrophy on the left and mild-to-moderate atrophy on the right), parietal operculum (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), central operculum (mild atrophy on the right), frontal operculum (no significant abnormality) and posterior insula (no significant abnormality)
- parietal lobe appears preserved, with no observable tissue loss
- mild atrophy of the right occipital lobe; normal-to-mild atrophy of the left occipital lobe; focal volume loss observed in the following subregions: inf. occipital gyrus (normal on the left and mild-to-moderate atrophy on the right), calcarine cortex (no significant abnormality), occipital fusiform gyrus (no significant abnormality), sup. occipital gyrus (no significant abnormality), occipital pole (no significant abnormality), middle occipital gyrus (no significant abnormality), cuneus (no significant abnormality) and lingual gyrus (no significant abnormality)
- limbic cortex demonstrates a healthy morphology without signs of atrophy
- mild atrophy of the right temporal lobe; the left temporal lobe is normal; focal volume loss observed in the following subregions: inf. temporal gyrus (no significant abnormality), fusiform gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), sup. temporal gyrus (normal on the left and mild-to-moderate atrophy on the right), transverse temporal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), temporal pole (mild atrophy on the left and normal-to-mild atrophy on the right), planum temporale (normal on the left and mild atrophy on the right), planum polare (no significant abnormality) and middle temporal gyrus (no significant abnormality)
|
PNFA
|
FTLD_203590286_02689_MR_Accelerated_Sagittal_IR-FSPGR_br_raw_202_I10176953_dupl_7
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- no appreciable degenerative or atrophic changes observed in the amygdala
- no clear atrophic alterations are visible in the putamen
- mild bilateral atrophy of the caudate
- no appreciable degenerative or atrophic changes observed in the basal forebrain
- hippocampus maintains a normal appearance with no observable atrophic features
- no clear atrophic alterations are visible in the thalamus
- mild atrophy of the left accumbens; the right accumbens is normal
- no observable atrophic changes in the ventral dc
- no evident atrophy or tissue thinning seen in the pallidum
For the ventricles:
- 3rd ventricle appears to be of normal dimensions, with no observable increase in size
- external csf appears to be of normal dimensions, with no observable increase in size
- no evident size increase noted in the 4th ventricle
- no evident size increase noted in the inf. lateral ventricle
- lateral ventricle maintains its expected proportions without signs of enlargement
For the cerebral cortex:
- parietal lobe maintains a normal appearance with no observable atrophic features
- no clear atrophic alterations are visible in the occipital lobe
- no evident atrophy or tissue thinning seen in the frontal lobe
- mild atrophy of the right temporal lobe; normal-to-mild atrophy of the left temporal lobe; focal volume loss observed in the following subregions: transverse temporal gyrus (no significant abnormality), temporal pole (mild atrophy both left/right), planum temporale (no significant abnormality), sup. temporal gyrus (mild atrophy on the left and normal on the right), fusiform gyrus (no significant abnormality), planum polare (no significant abnormality), middle temporal gyrus (no significant abnormality) and inf. temporal gyrus (no significant abnormality)
- no observable atrophic changes in the insular cortex
- no observable atrophic changes in the limbic cortex
|
PNFA
|
FTLD_203489181_03188_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10176905_dupl_3
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- no evident atrophy or tissue thinning seen in the amygdala
- pallidum demonstrates a healthy morphology without signs of atrophy
- the left hippocampus volume is borderline low
- the caudate shows no notable changes suggestive of atrophy
- no clear atrophic alterations are visible in the basal forebrain
- no clear atrophic alterations are visible in the thalamus
- ventral dc maintains a normal appearance with no observable atrophic features
- mild atrophy of the left accumbens; the right accumbens is normal
- putamen appears preserved, with no observable tissue loss
For the ventricles:
- mild enlargement of the 3rd ventricle
- mild-to-moderate enlargement of the right inf. lateral ventricle; the left inf. lateral ventricle is normal
- mild enlargement of the 4th ventricle
- mild-to-moderate bilateral enlargement of the lateral ventricle
- no evident size increase noted in the external csf
For the cerebral cortex:
- mild-to-moderate bilateral atrophy of the insular cortex; focal volume loss observed in the following subregions: anterior insula (mild atrophy both left/right), central operculum (normal-to-mild atrophy on the left and mild atrophy on the right), posterior insula (normal on the left and mild atrophy on the right), frontal operculum (mild atrophy on the left and normal on the right) and parietal operculum (mild atrophy on the left and normal on the right)
- the parietal lobe shows no notable changes suggestive of atrophy
- temporal lobe demonstrates a healthy morphology without signs of atrophy
- no evident atrophy or tissue thinning seen in the occipital lobe
- no observable atrophic changes in the frontal lobe
- no appreciable degenerative or atrophic changes observed in the limbic cortex
|
BV
|
FTLD_203063631_02136_MR_Sagittal_MP-Rage_br_raw_20230209095431440_I10183301_dupl_5
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- mild-to-moderate atrophy of the right insular cortex; the left insular cortex is normal; focal volume loss observed in the following subregions: anterior insula (mild-to-moderate atrophy on the left and moderate atrophy on the right), central operculum (normal on the left and mild-to-moderate atrophy on the right), parietal operculum (no significant abnormality), frontal operculum (mild atrophy on the left and normal on the right) and posterior insula (no significant abnormality)
- no appreciable degenerative or atrophic changes observed in the occipital lobe
- mild atrophy of the right limbic cortex; the left limbic cortex is normal; focal volume loss observed in the following subregions: middle cingulate gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), anterior cingulate gyrus (normal on the left and mild atrophy on the right), parahippocampal gyrus (no significant abnormality), entorhinal area (no significant abnormality) and posterior cingulate gyrus (no significant abnormality)
- mild-to-moderate atrophy of the left frontal lobe and severe atrophy of the right frontal lobe; focal volume loss observed in the following subregions: sup. frontal gyrus (moderate atrophy on the left and mild-to-moderate atrophy on the right), sup. frontal gyrus medial segment (mild atrophy both left/right), middle frontal gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), frontal pole (normal-to-mild atrophy on the left and mild atrophy on the right), opercular inf. frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), triangular inf. frontal gyrus (normal on the left and mild-to-moderate atrophy on the right), precentral gyrus (mild-to-moderate atrophy on the right), subcallosal area (no significant abnormality), anterior orbital gyrus (normal on the left and mild atrophy on the right), supplementary motor cortex (normal on the left and mild atrophy on the right), lateral orbital gyrus (no significant abnormality), precentral gyrus medial segment (no significant abnormality), orbital inf. frontal gyrus (no significant abnormality), medial frontal cortex (no significant abnormality), medial orbital gyrus (no significant abnormality), posterior orbital gyrus (no significant abnormality) and gyrus rectus (no significant abnormality)
- no evident atrophy or tissue thinning seen in the parietal lobe
- mild atrophy of the right temporal lobe; the left temporal lobe is normal; focal volume loss observed in the following subregions: middle temporal gyrus (mild-to-moderate atrophy on the right), transverse temporal gyrus (no significant abnormality), fusiform gyrus (no significant abnormality), planum polare (no significant abnormality), planum temporale (no significant abnormality), inf. temporal gyrus (no significant abnormality), sup. temporal gyrus (no significant abnormality) and temporal pole (no significant abnormality)
For the ventricles:
- severe enlargement of the right inf. lateral ventricle; the left inf. lateral ventricle is normal
- mild-to-moderate enlargement of the 3rd ventricle
- moderate enlargement of the external csf
- mild enlargement of the left lateral ventricle and moderate enlargement of the right lateral ventricle
- moderate-to-severe enlargement of the 4th ventricle
For the subcortical structures:
- mild-to-moderate atrophy of the right ventral dc; normal-to-mild atrophy of the left ventral dc
- mild atrophy of the left accumbens and mild-to-moderate atrophy of the right accumbens
- the left hippocampus volume is borderline low
- moderate atrophy of the left caudate and severe atrophy of the right caudate
- no appreciable degenerative or atrophic changes observed in the amygdala
- mild-to-moderate atrophy of the left pallidum and moderate-to-severe atrophy of the right pallidum
- moderate atrophy of the right thalamus; the left thalamus is normal
- moderate atrophy of the left putamen and moderate-to-severe atrophy of the right putamen
- no evident atrophy or tissue thinning seen in the basal forebrain
|
BV
|
FTLD_203014537_02731_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178217_dupl_12
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- no clear atrophic alterations are visible in the basal forebrain
- amygdala appears within normal limits without apparent atrophy
- mild atrophy of the left ventral dc; the right ventral dc is normal
- the thalamus shows no notable changes suggestive of atrophy
- moderate atrophy of the left pallidum; the right pallidum is normal
- mild atrophy of the left putamen; the right putamen is normal
- no clear atrophic alterations are visible in the accumbens
- hippocampus demonstrates a healthy morphology without signs of atrophy
- caudate appears within normal limits without apparent atrophy
For the cerebral cortex:
- no observable atrophic changes in the limbic cortex
- no clear atrophic alterations are visible in the temporal lobe
- mild atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: anterior insula (mild atrophy both left/right), frontal operculum (no significant abnormality), parietal operculum (no significant abnormality), posterior insula (no significant abnormality) and central operculum (no significant abnormality)
- no findings suggestive of atrophy are seen in the occipital lobe
- mild-to-moderate atrophy of the left frontal lobe and mild atrophy of the right frontal lobe; focal volume loss observed in the following subregions: precentral gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), middle frontal gyrus (mild atrophy both left/right), posterior orbital gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), lateral orbital gyrus (no significant abnormality), frontal pole (no significant abnormality), orbital inf. frontal gyrus (no significant abnormality), anterior orbital gyrus (mild atrophy on the left), subcallosal area (no significant abnormality), sup. frontal gyrus medial segment (normal on the left and mild atrophy on the right), triangular inf. frontal gyrus (no significant abnormality), opercular inf. frontal gyrus (no significant abnormality), medial frontal cortex (no significant abnormality), supplementary motor cortex (no significant abnormality), gyrus rectus (no significant abnormality), medial orbital gyrus (no significant abnormality), precentral gyrus medial segment (no significant abnormality) and sup. frontal gyrus (no significant abnormality)
- no findings suggestive of atrophy are seen in the parietal lobe
For the ventricles:
- no appreciable enlargement noted in the inf. lateral ventricle
- mild enlargement of the left lateral ventricle; normal-to-mild enlargement of the right lateral ventricle
- 3rd ventricle maintains a typical volume without observable enlargement
- no observable enlargement of the 4th ventricle
- no appreciable enlargement noted in the external csf
|
PNFA
|
FTLD_203231766_02663_MR_Accelerated_Sagittal_MPRAGE_Repeat_br_raw_I10178175_dupl_7
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- no appreciable degenerative or atrophic changes observed in the pallidum
- thalamus maintains a normal appearance with no observable atrophic features
- mild atrophy of the right caudate; the left caudate is normal
- no findings suggestive of atrophy are seen in the basal forebrain
- moderate-to-severe atrophy of the left amygdala and severe atrophy of the right amygdala
- mild atrophy of the right putamen; normal-to-mild atrophy of the left putamen
- ventral dc demonstrates a healthy morphology without signs of atrophy
- mild atrophy of the left accumbens and moderate atrophy of the right accumbens
- mild-to-moderate atrophy of the right hippocampus
For the ventricles:
- moderate enlargement of the right inf. lateral ventricle; the left inf. lateral ventricle is normal
- no evident size increase noted in the 3rd ventricle
- moderate enlargement of the external csf
- no appreciable enlargement noted in the 4th ventricle
- the lateral ventricle shows no notable changes suggestive of enlargement
For the cerebral cortex:
- mild atrophy of the right frontal lobe; the left frontal lobe is normal; focal volume loss observed in the following subregions: subcallosal area (mild atrophy on the left and mild-to-moderate atrophy on the right), frontal pole (mild atrophy both left/right), gyrus rectus (mild atrophy both left/right), sup. frontal gyrus medial segment (no significant abnormality), middle frontal gyrus (normal on the left and mild atrophy on the right), supplementary motor cortex (no significant abnormality), lateral orbital gyrus (no significant abnormality), precentral gyrus (no significant abnormality), opercular inf. frontal gyrus (no significant abnormality), orbital inf. frontal gyrus (no significant abnormality), triangular inf. frontal gyrus (no significant abnormality), medial frontal cortex (no significant abnormality), anterior orbital gyrus (no significant abnormality), medial orbital gyrus (no significant abnormality), posterior orbital gyrus (no significant abnormality), precentral gyrus medial segment (no significant abnormality) and sup. frontal gyrus (no significant abnormality)
- parietal lobe appears preserved, with no observable tissue loss
- mild-to-moderate bilateral atrophy of the limbic cortex; focal volume loss observed in the following subregions: parahippocampal gyrus (mild-to-moderate atrophy on the left and moderate atrophy on the right), entorhinal area (mild atrophy on the left and moderate atrophy on the right), middle cingulate gyrus (mild atrophy both left/right), anterior cingulate gyrus (mild atrophy on the left and normal on the right) and posterior cingulate gyrus (no significant abnormality)
- mild-to-moderate atrophy of the right insular cortex; the left insular cortex is normal; focal volume loss observed in the following subregions: posterior insula (mild-to-moderate atrophy on the left and moderate-to-severe atrophy on the right), anterior insula (normal on the left and moderate atrophy on the right), frontal operculum (normal-to-mild atrophy on the left and mild atrophy on the right), parietal operculum (no significant abnormality) and central operculum (no significant abnormality)
- moderate atrophy of the left temporal lobe and severe atrophy of the right temporal lobe; focal volume loss observed in the following subregions: middle temporal gyrus (mild atrophy on the left and moderate-to-severe atrophy on the right), temporal pole (mild atrophy on the left and moderate-to-severe atrophy on the right), fusiform gyrus (mild-to-moderate atrophy both left/right), inf. temporal gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), sup. temporal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), planum polare (no significant abnormality), transverse temporal gyrus (no significant abnormality) and planum temporale (no significant abnormality)
- no evident atrophy or tissue thinning seen in the occipital lobe
|
SV
|
ADNI_094_S_4089_MR_Accelerated_SAG_IR-SPGR__br_raw_20110630122131904_28_S113223_I242720_dupl_1
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: parahippocampal gyrus (mild atrophy both left/right), entorhinal area (no significant abnormality), posterior cingulate gyrus (mild atrophy on the left), anterior cingulate gyrus (no significant abnormality) and middle cingulate gyrus (no significant abnormality)
- mild-to-moderate atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: temporal pole (mild-to-moderate atrophy on the left and mild atrophy on the right), planum polare (normal-to-mild atrophy on the left and mild atrophy on the right), planum temporale (no significant abnormality), inf. temporal gyrus (mild atrophy on the left), transverse temporal gyrus (no significant abnormality), fusiform gyrus (no significant abnormality), middle temporal gyrus (no significant abnormality) and sup. temporal gyrus (no significant abnormality)
- mild atrophy of the right parietal lobe; normal-to-mild atrophy of the left parietal lobe; focal volume loss observed in the following subregions: angular gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), precuneus (mild atrophy on the left and normal-to-mild atrophy on the right), postcentral gyrus (no significant abnormality), postcentral gyrus medial segment (mild atrophy on the left and normal on the right), sup. parietal lobule (mild atrophy on the left and normal on the right) and supramarginal gyrus (no significant abnormality)
- the occipital lobe shows no notable changes suggestive of atrophy
- no clear atrophic alterations are visible in the frontal lobe
- insular cortex maintains a normal appearance with no observable atrophic features
For the subcortical structures:
- no findings suggestive of atrophy are seen in the basal forebrain
- severe atrophy of the left amygdala and mild-to-moderate atrophy of the right amygdala
- caudate maintains a normal appearance with no observable atrophic features
- the ventral dc shows no notable changes suggestive of atrophy
- mild atrophy of the left putamen; normal-to-mild atrophy of the right putamen
- mild-to-moderate atrophy of the left hippocampus
- the left hippocampus volume is borderline low
- mild atrophy of the left thalamus; the right thalamus is normal
- mild atrophy of the left accumbens; normal-to-mild atrophy of the right accumbens
- pallidum maintains a normal appearance with no observable atrophic features
For the ventricles:
- no evident size increase noted in the 4th ventricle
- 3rd ventricle appears within normal size limits with no apparent enlargement
- no evident size increase noted in the lateral ventricle
- mild enlargement of the external csf
- moderate enlargement of the left inf. lateral ventricle and mild enlargement of the right inf. lateral ventricle
|
AD
|
FTLD_203966778_01876_MR_Sagittal_MP-Rage_br_raw_20230206175323985_I10182277_dupl_3
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- occipital lobe appears preserved, with no observable tissue loss
- no clear atrophic alterations are visible in the temporal lobe
- no clear atrophic alterations are visible in the limbic cortex
- insular cortex appears preserved, with no observable tissue loss
- the parietal lobe shows no notable changes suggestive of atrophy
- mild bilateral atrophy of the frontal lobe; focal volume loss observed in the following subregions: supplementary motor cortex (no significant abnormality), subcallosal area (no significant abnormality), frontal pole (mild atrophy both left/right), gyrus rectus (mild atrophy both left/right), triangular inf. frontal gyrus (normal on the left and mild-to-moderate atrophy on the right), lateral orbital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), precentral gyrus medial segment (mild atrophy on the left and normal-to-mild atrophy on the right), medial frontal cortex (normal on the left and mild atrophy on the right), sup. frontal gyrus medial segment (normal on the left and mild atrophy on the right), medial orbital gyrus (no significant abnormality), posterior orbital gyrus (mild atrophy on the left and normal on the right), middle frontal gyrus (no significant abnormality), opercular inf. frontal gyrus (no significant abnormality), anterior orbital gyrus (no significant abnormality), precentral gyrus (no significant abnormality), orbital inf. frontal gyrus (no significant abnormality) and sup. frontal gyrus (no significant abnormality)
For the subcortical structures:
- mild bilateral atrophy of the ventral dc
- mild atrophy of the right putamen; normal-to-mild atrophy of the left putamen
- mild bilateral atrophy of the thalamus
- mild bilateral atrophy of the accumbens
- the left hippocampus volume is borderline low
- the left hippocampus volume is borderline low
- mild bilateral atrophy of the pallidum
- mild atrophy of the right amygdala; normal-to-mild atrophy of the left amygdala
- mild atrophy of the right caudate; normal-to-mild atrophy of the left caudate
- no observable atrophic changes in the basal forebrain
For the ventricles:
- moderate-to-severe enlargement of the left lateral ventricle and moderate enlargement of the right lateral ventricle
- no evident size increase noted in the external csf
- no evident size increase noted in the 4th ventricle
- moderate bilateral enlargement of the inf. lateral ventricle
- mild enlargement of the 3rd ventricle
|
BV
|
FTLD_203432376_01673_MR_Sagittal_MP-Rage_br_raw_20230206145827122_I10181308_dupl_2
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- no observable atrophic changes in the basal forebrain
- thalamus appears preserved, with no observable tissue loss
- mild-to-moderate atrophy of the left accumbens and moderate atrophy of the right accumbens
- no appreciable degenerative or atrophic changes observed in the hippocampus
- mild-to-moderate atrophy of the left putamen and moderate atrophy of the right putamen
- ventral dc maintains a normal appearance with no observable atrophic features
- mild atrophy of the right caudate; normal-to-mild atrophy of the left caudate
- moderate bilateral atrophy of the amygdala
- mild atrophy of the left pallidum and mild-to-moderate atrophy of the right pallidum
For the ventricles:
- moderate-to-severe enlargement of the external csf
- no appreciable enlargement noted in the lateral ventricle
- no clear enlargement or abnormal growth seen in the inf. lateral ventricle
- mild enlargement of the 4th ventricle
- the 3rd ventricle shows no notable changes suggestive of enlargement
For the cerebral cortex:
- no findings suggestive of atrophy are seen in the parietal lobe
- mild atrophy of the right occipital lobe; normal-to-mild atrophy of the left occipital lobe; focal volume loss observed in the following subregions: inf. occipital gyrus (normal on the left and mild-to-moderate atrophy on the right), calcarine cortex (no significant abnormality), occipital fusiform gyrus (no significant abnormality), sup. occipital gyrus (no significant abnormality), occipital pole (no significant abnormality), middle occipital gyrus (no significant abnormality), cuneus (no significant abnormality) and lingual gyrus (no significant abnormality)
- mild atrophy of the left frontal lobe and moderate atrophy of the right frontal lobe; focal volume loss observed in the following subregions: frontal pole (mild atrophy on the left and moderate atrophy on the right), middle frontal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), lateral orbital gyrus (no significant abnormality), sup. frontal gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), triangular inf. frontal gyrus (no significant abnormality), medial frontal cortex (normal on the left and mild atrophy on the right), anterior orbital gyrus (normal on the left and mild atrophy on the right), orbital inf. frontal gyrus (no significant abnormality), precentral gyrus (normal on the left and mild atrophy on the right), supplementary motor cortex (no significant abnormality), precentral gyrus medial segment (no significant abnormality), opercular inf. frontal gyrus (no significant abnormality), sup. frontal gyrus medial segment (no significant abnormality), gyrus rectus (no significant abnormality), medial orbital gyrus (no significant abnormality), posterior orbital gyrus (no significant abnormality) and subcallosal area (no significant abnormality)
- mild atrophy of the right temporal lobe; the left temporal lobe is normal; focal volume loss observed in the following subregions: inf. temporal gyrus (no significant abnormality), fusiform gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), sup. temporal gyrus (normal on the left and mild-to-moderate atrophy on the right), transverse temporal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), temporal pole (mild atrophy on the left and normal-to-mild atrophy on the right), planum temporale (normal on the left and mild atrophy on the right), planum polare (no significant abnormality) and middle temporal gyrus (no significant abnormality)
- no observable atrophic changes in the limbic cortex
- mild atrophy of the left insular cortex and moderate atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (mild atrophy on the left and mild-to-moderate atrophy on the right), parietal operculum (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), central operculum (mild atrophy on the right), frontal operculum (no significant abnormality) and posterior insula (no significant abnormality)
|
PNFA
|
FTLD_203170195_03597_MR_Accelerated_Sagittal_MPRAGE_br_raw_20241_I11047609_dupl_7
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- severe enlargement of the external csf
- mild-to-moderate bilateral enlargement of the lateral ventricle
- mild enlargement of the 3rd ventricle
- severe enlargement of the left inf. lateral ventricle and mild-to-moderate enlargement of the right inf. lateral ventricle
- mild enlargement of the 4th ventricle
For the subcortical structures:
- mild-to-moderate atrophy of the left thalamus; normal-to-mild atrophy of the right thalamus
- severe atrophy of the left accumbens and moderate-to-severe atrophy of the right accumbens
- no observable atrophic changes in the ventral dc
- mild-to-moderate atrophy of the left pallidum; the right pallidum is normal
- severe atrophy of the left caudate and moderate-to-severe atrophy of the right caudate
- basal forebrain appears preserved, with no observable tissue loss
- severe atrophy of the left putamen and mild-to-moderate atrophy of the right putamen
- moderate-to-severe atrophy of the left amygdala and mild atrophy of the right amygdala
- the left hippocampus volume is borderline low
- the left hippocampus volume is borderline low
For the cerebral cortex:
- no observable atrophic changes in the occipital lobe
- moderate-to-severe atrophy of the left limbic cortex and mild atrophy of the right limbic cortex; focal volume loss observed in the following subregions: anterior cingulate gyrus (moderate-to-severe atrophy on the left and moderate atrophy on the right), parahippocampal gyrus (mild atrophy on the left), middle cingulate gyrus (mild-to-moderate atrophy on the left and normal on the right), posterior cingulate gyrus (no significant abnormality) and entorhinal area (no significant abnormality)
- moderate atrophy of the left temporal lobe and mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate atrophy on the left and mild atrophy on the right), inf. temporal gyrus (moderate atrophy on the left), planum temporale (mild atrophy on the right), middle temporal gyrus (mild atrophy on the left and normal on the right), fusiform gyrus (normal on the left and mild atrophy on the right), transverse temporal gyrus (no significant abnormality), planum polare (no significant abnormality) and sup. temporal gyrus (no significant abnormality)
- severe atrophy of the left frontal lobe and moderate-to-severe atrophy of the right frontal lobe; focal volume loss observed in the following subregions: gyrus rectus (severe atrophy on the left and moderate atrophy on the right), medial orbital gyrus (severe atrophy on the left and mild-to-moderate atrophy on the right), frontal pole (moderate-to-severe atrophy on the left and moderate atrophy on the right), posterior orbital gyrus (severe atrophy on the left and mild atrophy on the right), sup. frontal gyrus medial segment (moderate atrophy both left/right), middle frontal gyrus (moderate-to-severe atrophy on the left and mild atrophy on the right), lateral orbital gyrus (moderate atrophy on the left and mild-to-moderate atrophy on the right), sup. frontal gyrus (moderate-to-severe atrophy on the left and mild atrophy on the right), medial frontal cortex (moderate atrophy on the left and mild atrophy on the right), subcallosal area (mild-to-moderate atrophy both left/right), anterior orbital gyrus (moderate atrophy on the left and normal on the right), opercular inf. frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), orbital inf. frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), triangular inf. frontal gyrus (normal on the left and mild atrophy on the right), precentral gyrus (no significant abnormality), precentral gyrus medial segment (no significant abnormality) and supplementary motor cortex (no significant abnormality)
- moderate-to-severe bilateral atrophy of the insular cortex; focal volume loss observed in the following subregions: anterior insula (severe atrophy on the left and moderate-to-severe atrophy on the right), frontal operculum (mild-to-moderate atrophy both left/right), posterior insula (mild atrophy both left/right), parietal operculum (mild atrophy on the right) and central operculum (mild atrophy on the left and normal on the right)
- no evident atrophy or tissue thinning seen in the parietal lobe
|
BV
|
FTLD_203794298_03899_MR_Accelerated_Sagittal_MPRAGE_br_raw_20241_I11047963
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- the pallidum shows no notable changes suggestive of atrophy
- no appreciable degenerative or atrophic changes observed in the accumbens
- amygdala demonstrates a healthy morphology without signs of atrophy
- basal forebrain demonstrates a healthy morphology without signs of atrophy
- thalamus appears within normal limits without apparent atrophy
- no findings suggestive of atrophy are seen in the caudate
- no observable atrophic changes in the hippocampus
- no appreciable degenerative or atrophic changes observed in the ventral dc
- no observable atrophic changes in the putamen
For the ventricles:
- no observable enlargement of the 3rd ventricle
- lateral ventricle appears to be of normal dimensions, with no observable increase in size
- 4th ventricle appears within normal size limits with no apparent enlargement
- no observable enlargement of the inf. lateral ventricle
- no observable enlargement of the external csf
For the cerebral cortex:
- temporal lobe maintains a normal appearance with no observable atrophic features
- no observable atrophic changes in the occipital lobe
- the limbic cortex shows no notable changes suggestive of atrophy
- parietal lobe appears within normal limits without apparent atrophy
- insular cortex appears within normal limits without apparent atrophy
- frontal lobe demonstrates a healthy morphology without signs of atrophy
|
CN
|
FTLD_203760928_02826_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178306_dupl_5
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- severe atrophy of the left temporal lobe and moderate-to-severe atrophy of the right temporal lobe; focal volume loss observed in the following subregions: middle temporal gyrus (moderate atrophy on the left and mild-to-moderate atrophy on the right), inf. temporal gyrus (mild-to-moderate atrophy both left/right), fusiform gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), temporal pole (mild-to-moderate atrophy on the left and mild atrophy on the right), planum polare (normal on the left and mild-to-moderate atrophy on the right), planum temporale (mild atrophy on the left and normal on the right), sup. temporal gyrus (no significant abnormality) and transverse temporal gyrus (no significant abnormality)
- the occipital lobe shows no notable changes suggestive of atrophy
- mild-to-moderate atrophy of the left frontal lobe and mild atrophy of the right frontal lobe; focal volume loss observed in the following subregions: middle frontal gyrus (mild atrophy both left/right), subcallosal area (mild atrophy both left/right), lateral orbital gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), orbital inf. frontal gyrus (no significant abnormality), frontal pole (normal on the left and mild atrophy on the right), anterior orbital gyrus (mild atrophy on the left and normal on the right), precentral gyrus (mild atrophy on the left and normal on the right), precentral gyrus medial segment (mild atrophy on the left and normal on the right), supplementary motor cortex (no significant abnormality), gyrus rectus (mild atrophy on the left), medial orbital gyrus (mild atrophy on the left), posterior orbital gyrus (no significant abnormality), sup. frontal gyrus (no significant abnormality), opercular inf. frontal gyrus (no significant abnormality), triangular inf. frontal gyrus (no significant abnormality), medial frontal cortex (no significant abnormality) and sup. frontal gyrus medial segment (no significant abnormality)
- mild-to-moderate atrophy of the left parietal lobe and mild atrophy of the right parietal lobe; focal volume loss observed in the following subregions: precuneus (mild-to-moderate atrophy on the left and mild atrophy on the right), angular gyrus (mild atrophy both left/right), postcentral gyrus medial segment (mild atrophy on the left and normal-to-mild atrophy on the right), sup. parietal lobule (no significant abnormality), postcentral gyrus (no significant abnormality) and supramarginal gyrus (no significant abnormality)
- mild-to-moderate atrophy of the left limbic cortex and moderate atrophy of the right limbic cortex; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild-to-moderate atrophy both left/right), parahippocampal gyrus (mild atrophy both left/right), entorhinal area (mild atrophy on the left and normal-to-mild atrophy on the right), middle cingulate gyrus (normal on the left and mild atrophy on the right) and posterior cingulate gyrus (mild atrophy on the right)
- moderate atrophy of the left insular cortex and mild-to-moderate atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate atrophy on the left and mild-to-moderate atrophy on the right), posterior insula (mild atrophy both left/right), frontal operculum (normal-to-mild atrophy on the left and mild atrophy on the right), parietal operculum (mild atrophy on the left and normal-to-mild atrophy on the right) and central operculum (no significant abnormality)
For the subcortical structures:
- moderate atrophy of the left putamen and mild-to-moderate atrophy of the right putamen
- mild-to-moderate atrophy of the left pallidum and mild atrophy of the right pallidum
- mild-to-moderate atrophy of the left hippocampus
- moderate atrophy of the right hippocampus
- moderate bilateral atrophy of the caudate
- severe atrophy of the left accumbens and moderate-to-severe atrophy of the right accumbens
- no observable atrophic changes in the basal forebrain
- no clear atrophic alterations are visible in the thalamus
- no appreciable degenerative or atrophic changes observed in the ventral dc
- moderate-to-severe atrophy of the left amygdala and severe atrophy of the right amygdala
For the ventricles:
- no findings suggestive of enlargement are seen in the 4th ventricle
- moderate-to-severe enlargement of the external csf
- mild-to-moderate enlargement of the 3rd ventricle
- moderate-to-severe enlargement of the left inf. lateral ventricle and severe enlargement of the right inf. lateral ventricle
- mild enlargement of the right lateral ventricle; normal-to-mild enlargement of the left lateral ventricle
|
BV
|
FTLD_203997070_03079_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177924_dupl_6
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- mild enlargement of the right inf. lateral ventricle; normal-to-mild enlargement of the left inf. lateral ventricle
- mild-to-moderate bilateral enlargement of the lateral ventricle
- the 4th ventricle shows no notable changes suggestive of enlargement
- mild-to-moderate enlargement of the external csf
- 3rd ventricle maintains its expected proportions without signs of enlargement
For the cerebral cortex:
- mild-to-moderate atrophy of the right temporal lobe; the left temporal lobe is normal; focal volume loss observed in the following subregions: temporal pole (mild atrophy on the left and mild-to-moderate atrophy on the right), fusiform gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), inf. temporal gyrus (normal on the left and mild-to-moderate atrophy on the right), middle temporal gyrus (no significant abnormality), sup. temporal gyrus (no significant abnormality), transverse temporal gyrus (no significant abnormality), planum polare (no significant abnormality) and planum temporale (no significant abnormality)
- moderate atrophy of the left limbic cortex and moderate-to-severe atrophy of the right limbic cortex; focal volume loss observed in the following subregions: anterior cingulate gyrus (moderate atrophy both left/right), posterior cingulate gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), entorhinal area (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), parahippocampal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and middle cingulate gyrus (no significant abnormality)
- mild-to-moderate atrophy of the right insular cortex; the left insular cortex is normal; focal volume loss observed in the following subregions: anterior insula (moderate atrophy on the left and moderate-to-severe atrophy on the right), posterior insula (mild atrophy on the right), frontal operculum (mild atrophy on the left and normal-to-mild atrophy on the right), parietal operculum (no significant abnormality) and central operculum (no significant abnormality)
- occipital lobe demonstrates a healthy morphology without signs of atrophy
- parietal lobe demonstrates a healthy morphology without signs of atrophy
- mild-to-moderate atrophy of the left frontal lobe and severe atrophy of the right frontal lobe; focal volume loss observed in the following subregions: medial orbital gyrus (moderate atrophy both left/right), medial frontal cortex (moderate atrophy on the left and mild-to-moderate atrophy on the right), gyrus rectus (mild-to-moderate atrophy both left/right), lateral orbital gyrus (mild atrophy on the left and moderate atrophy on the right), middle frontal gyrus (mild atrophy on the left and moderate atrophy on the right), posterior orbital gyrus (mild-to-moderate atrophy both left/right), frontal pole (mild atrophy on the left and mild-to-moderate atrophy on the right), anterior orbital gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), triangular inf. frontal gyrus (mild-to-moderate atrophy on the right), precentral gyrus medial segment (no significant abnormality), sup. frontal gyrus medial segment (normal on the left and mild atrophy on the right), supplementary motor cortex (normal on the left and mild atrophy on the right), sup. frontal gyrus (mild atrophy on the left and normal on the right), precentral gyrus (no significant abnormality), orbital inf. frontal gyrus (no significant abnormality), subcallosal area (no significant abnormality) and opercular inf. frontal gyrus (no significant abnormality)
For the subcortical structures:
- moderate-to-severe atrophy of the left amygdala and severe atrophy of the right amygdala
- no clear atrophic alterations are visible in the basal forebrain
- moderate atrophy of the left putamen and severe atrophy of the right putamen
- mild atrophy of the left hippocampus
- mild-to-moderate atrophy of the right hippocampus
- severe bilateral atrophy of the accumbens
- mild atrophy of the right thalamus; the left thalamus is normal
- mild-to-moderate atrophy of the right pallidum; normal-to-mild atrophy of the left pallidum
- no evident atrophy or tissue thinning seen in the ventral dc
- moderate atrophy of the left caudate and severe atrophy of the right caudate
|
BV
|
ADNI_130_S_4660_MR_MPRAGE_br_raw_20120423092147818_143_S148079_I300034_dupl_1
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- no findings suggestive of atrophy are seen in the ventral dc
- mild-to-moderate atrophy of the right amygdala; normal-to-mild atrophy of the left amygdala
- mild atrophy of the left hippocampus
- mild-to-moderate atrophy of the right hippocampus
- no appreciable degenerative or atrophic changes observed in the basal forebrain
- the putamen shows no notable changes suggestive of atrophy
- no evident atrophy or tissue thinning seen in the accumbens
- no observable atrophic changes in the caudate
- mild atrophy of the left pallidum; normal-to-mild atrophy of the right pallidum
- thalamus appears within normal limits without apparent atrophy
For the cerebral cortex:
- mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy on the left), middle cingulate gyrus (no significant abnormality), parahippocampal gyrus (no significant abnormality), entorhinal area (no significant abnormality) and posterior cingulate gyrus (no significant abnormality)
- no findings suggestive of atrophy are seen in the occipital lobe
- mild atrophy of the left parietal lobe; the right parietal lobe is normal; focal volume loss observed in the following subregions: postcentral gyrus medial segment (no significant abnormality), supramarginal gyrus (mild atrophy on the left), postcentral gyrus (no significant abnormality), precuneus (no significant abnormality), sup. parietal lobule (no significant abnormality) and angular gyrus (no significant abnormality)
- the frontal lobe shows no notable changes suggestive of atrophy
- no observable atrophic changes in the temporal lobe
- insular cortex appears within normal limits without apparent atrophy
For the ventricles:
- mild enlargement of the external csf
- 4th ventricle appears to be of normal dimensions, with no observable increase in size
- the lateral ventricle shows no notable changes suggestive of enlargement
- no observable enlargement of the inf. lateral ventricle
- 3rd ventricle maintains its expected proportions without signs of enlargement
|
AD
|
FTLD_203805483_02380_MR_Sagittal_MP-Rage_br_raw_20230209101607742_I10183415
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- ventral dc demonstrates a healthy morphology without signs of atrophy
- no findings suggestive of atrophy are seen in the amygdala
- accumbens appears within normal limits without apparent atrophy
- thalamus appears within normal limits without apparent atrophy
- putamen appears preserved, with no observable tissue loss
- pallidum appears within normal limits without apparent atrophy
- the basal forebrain shows no notable changes suggestive of atrophy
- caudate demonstrates a healthy morphology without signs of atrophy
- no observable atrophic changes in the hippocampus
For the cerebral cortex:
- occipital lobe appears within normal limits without apparent atrophy
- mild atrophy of the left insular cortex; normal-to-mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: central operculum (mild atrophy on the left and normal-to-mild atrophy on the right), parietal operculum (mild atrophy on the left and normal-to-mild atrophy on the right), anterior insula (no significant abnormality), posterior insula (no significant abnormality) and frontal operculum (no significant abnormality)
- no observable atrophic changes in the parietal lobe
- no clear atrophic alterations are visible in the limbic cortex
- frontal lobe appears preserved, with no observable tissue loss
- no appreciable degenerative or atrophic changes observed in the temporal lobe
For the ventricles:
- no clear enlargement or abnormal growth seen in the lateral ventricle
- 4th ventricle maintains a typical volume without observable enlargement
- external csf appears within normal size limits with no apparent enlargement
- no evident size increase noted in the 3rd ventricle
- inf. lateral ventricle appears to be of normal dimensions, with no observable increase in size
|
CN
|
ADNI_035_S_0997_MR_MPR__GradWarp__B1_Correction__N3__Scaled_Br_20081017105328574_S53638_I121831_dupl_1
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- occipital lobe maintains a normal appearance with no observable atrophic features
- limbic cortex maintains a normal appearance with no observable atrophic features
- no evident atrophy or tissue thinning seen in the parietal lobe
- moderate-to-severe atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: temporal pole (moderate-to-severe atrophy on the left and normal-to-mild atrophy on the right), fusiform gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), inf. temporal gyrus (mild-to-moderate atrophy on the left), planum polare (no significant abnormality), planum temporale (mild atrophy on the left and normal on the right), transverse temporal gyrus (no significant abnormality), middle temporal gyrus (no significant abnormality) and sup. temporal gyrus (no significant abnormality)
- mild atrophy of the right insular cortex; normal-to-mild atrophy of the left insular cortex; focal volume loss observed in the following subregions: anterior insula (mild atrophy both left/right), posterior insula (mild atrophy both left/right), parietal operculum (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), central operculum (no significant abnormality) and frontal operculum (no significant abnormality)
- the frontal lobe shows no notable changes suggestive of atrophy
For the subcortical structures:
- no clear atrophic alterations are visible in the putamen
- severe atrophy of the left amygdala and mild-to-moderate atrophy of the right amygdala
- no appreciable degenerative or atrophic changes observed in the basal forebrain
- moderate-to-severe atrophy of the left hippocampus
- mild-to-moderate atrophy of the right hippocampus
- no evident atrophy or tissue thinning seen in the pallidum
- thalamus appears preserved, with no observable tissue loss
- no evident atrophy or tissue thinning seen in the caudate
- mild atrophy of the left ventral dc; normal-to-mild atrophy of the right ventral dc
- mild bilateral atrophy of the accumbens
For the ventricles:
- external csf appears within normal size limits with no apparent enlargement
- mild-to-moderate bilateral enlargement of the inf. lateral ventricle
- no observable enlargement of the lateral ventricle
- mild enlargement of the 4th ventricle
- no evident size increase noted in the 3rd ventricle
|
AD
|
FTLD_203163034_02436_MR_Sagittal_MP-Rage_br_raw_20230209101942649_I10183429_dupl_8
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- no clear atrophic alterations are visible in the limbic cortex
- no clear atrophic alterations are visible in the parietal lobe
- mild atrophy of the left frontal lobe; normal-to-mild atrophy of the right frontal lobe; focal volume loss observed in the following subregions: opercular inf. frontal gyrus (mild atrophy both left/right), posterior orbital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), sup. frontal gyrus medial segment (no significant abnormality), supplementary motor cortex (mild-to-moderate atrophy on the left and normal on the right), gyrus rectus (mild atrophy on the left and normal on the right), middle frontal gyrus (no significant abnormality), orbital inf. frontal gyrus (no significant abnormality), triangular inf. frontal gyrus (mild atrophy on the left and normal on the right), sup. frontal gyrus (no significant abnormality), anterior orbital gyrus (no significant abnormality), lateral orbital gyrus (no significant abnormality), subcallosal area (no significant abnormality), frontal pole (no significant abnormality), medial frontal cortex (no significant abnormality), medial orbital gyrus (no significant abnormality), precentral gyrus (no significant abnormality) and precentral gyrus medial segment (no significant abnormality)
- no evident atrophy or tissue thinning seen in the occipital lobe
- the insular cortex shows no notable changes suggestive of atrophy
- no findings suggestive of atrophy are seen in the temporal lobe
For the ventricles:
- inf. lateral ventricle appears within normal size limits with no apparent enlargement
- mild-to-moderate enlargement of the external csf
- lateral ventricle appears within normal size limits with no apparent enlargement
- no clear enlargement or abnormal growth seen in the 4th ventricle
- the 3rd ventricle shows no notable changes suggestive of enlargement
For the subcortical structures:
- no evident atrophy or tissue thinning seen in the thalamus
- mild atrophy of the left amygdala; the right amygdala is normal
- no findings suggestive of atrophy are seen in the basal forebrain
- mild bilateral atrophy of the caudate
- no findings suggestive of atrophy are seen in the hippocampus
- ventral dc demonstrates a healthy morphology without signs of atrophy
- mild-to-moderate atrophy of the left accumbens and mild atrophy of the right accumbens
- mild bilateral atrophy of the pallidum
- mild atrophy of the left putamen; normal-to-mild atrophy of the right putamen
|
PNFA
|
ADNI_032_S_0978_MR_MPR____N3__Scaled_Br_20090129130739856_S61100_I134905_dupl_1
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- the accumbens shows no notable changes suggestive of atrophy
- mild bilateral atrophy of the putamen
- caudate appears preserved, with no observable tissue loss
- ventral dc appears within normal limits without apparent atrophy
- mild bilateral atrophy of the amygdala
- no findings suggestive of atrophy are seen in the basal forebrain
- mild atrophy of the left hippocampus
- mild atrophy of the right hippocampus
- mild bilateral atrophy of the pallidum
- no findings suggestive of atrophy are seen in the thalamus
For the ventricles:
- no observable enlargement of the 3rd ventricle
- mild enlargement of the right inf. lateral ventricle; normal-to-mild enlargement of the left inf. lateral ventricle
- lateral ventricle appears to be of normal dimensions, with no observable increase in size
- no findings suggestive of enlargement are seen in the 4th ventricle
- external csf maintains a typical volume without observable enlargement
For the cerebral cortex:
- limbic cortex appears preserved, with no observable tissue loss
- no observable atrophic changes in the parietal lobe
- no observable atrophic changes in the temporal lobe
- mild atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: posterior insula (mild atrophy on the left and normal-to-mild atrophy on the right), central operculum (no significant abnormality), parietal operculum (no significant abnormality), anterior insula (no significant abnormality) and frontal operculum (no significant abnormality)
- no appreciable degenerative or atrophic changes observed in the frontal lobe
- no clear atrophic alterations are visible in the occipital lobe
|
AD
|
FTLD_203447962_03264_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10177413_dupl_17
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- mild enlargement of the right lateral ventricle; the left lateral ventricle is normal
- mild enlargement of the 3rd ventricle
- severe bilateral enlargement of the inf. lateral ventricle
- no findings suggestive of enlargement are seen in the 4th ventricle
- mild enlargement of the external csf
For the cerebral cortex:
- mild atrophy of the left insular cortex and moderate atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate atrophy on the left and severe atrophy on the right), posterior insula (mild atrophy on the left and mild-to-moderate atrophy on the right), parietal operculum (no significant abnormality), central operculum (no significant abnormality) and frontal operculum (no significant abnormality)
- occipital lobe demonstrates a healthy morphology without signs of atrophy
- severe bilateral atrophy of the temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate-to-severe atrophy both left/right), fusiform gyrus (mild-to-moderate atrophy on the left and moderate atrophy on the right), inf. temporal gyrus (mild-to-moderate atrophy on the left and moderate atrophy on the right), sup. temporal gyrus (mild atrophy on the left and moderate atrophy on the right), middle temporal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), planum polare (no significant abnormality), planum temporale (no significant abnormality) and transverse temporal gyrus (no significant abnormality)
- mild-to-moderate bilateral atrophy of the limbic cortex; focal volume loss observed in the following subregions: entorhinal area (moderate atrophy both left/right), anterior cingulate gyrus (mild atrophy both left/right), parahippocampal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), middle cingulate gyrus (no significant abnormality) and posterior cingulate gyrus (no significant abnormality)
- frontal lobe maintains a normal appearance with no observable atrophic features
- parietal lobe maintains a normal appearance with no observable atrophic features
For the subcortical structures:
- mild atrophy of the left hippocampus
- mild-to-moderate atrophy of the right hippocampus
- mild atrophy of the left pallidum and moderate atrophy of the right pallidum
- no evident atrophy or tissue thinning seen in the basal forebrain
- moderate-to-severe atrophy of the left accumbens and severe atrophy of the right accumbens
- severe bilateral atrophy of the amygdala
- no observable atrophic changes in the thalamus
- mild-to-moderate atrophy of the left caudate and mild atrophy of the right caudate
- no appreciable degenerative or atrophic changes observed in the ventral dc
- mild atrophy of the left putamen and severe atrophy of the right putamen
|
SV
|
ADNI_098_S_4215_MR_Accelerated_Sag_IR-SPGR__br_raw_20110913152714124_180_S121936_I255836_dupl_1
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- no observable atrophic changes in the frontal lobe
- mild atrophy of the right limbic cortex; normal-to-mild atrophy of the left limbic cortex; focal volume loss observed in the following subregions: anterior cingulate gyrus (normal on the left and mild atrophy on the right), middle cingulate gyrus (mild atrophy on the left and normal on the right), entorhinal area (no significant abnormality), posterior cingulate gyrus (no significant abnormality) and parahippocampal gyrus (no significant abnormality)
- temporal lobe appears preserved, with no observable tissue loss
- no clear atrophic alterations are visible in the occipital lobe
- insular cortex demonstrates a healthy morphology without signs of atrophy
- parietal lobe demonstrates a healthy morphology without signs of atrophy
For the subcortical structures:
- no observable atrophic changes in the ventral dc
- no observable atrophic changes in the basal forebrain
- amygdala demonstrates a healthy morphology without signs of atrophy
- caudate demonstrates a healthy morphology without signs of atrophy
- thalamus appears preserved, with no observable tissue loss
- mild atrophy of the left hippocampus
- mild atrophy of the right hippocampus
- no findings suggestive of atrophy are seen in the accumbens
- putamen appears within normal limits without apparent atrophy
- no findings suggestive of atrophy are seen in the pallidum
For the ventricles:
- no clear enlargement or abnormal growth seen in the lateral ventricle
- mild enlargement of the left inf. lateral ventricle; normal-to-mild enlargement of the right inf. lateral ventricle
- 4th ventricle appears within normal size limits with no apparent enlargement
- no observable enlargement of the 3rd ventricle
- external csf maintains its expected proportions without signs of enlargement
|
AD
|
ADNI_941_S_6514_MR_Accelerated_Sagittal_MPRAGE__br_raw_20180727104527197_65_S709616_I1027315
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- no evident size increase noted in the external csf
- no observable enlargement of the inf. lateral ventricle
- lateral ventricle maintains its expected proportions without signs of enlargement
- 3rd ventricle maintains a typical volume without observable enlargement
- no observable enlargement of the 4th ventricle
For the subcortical structures:
- pallidum maintains a normal appearance with no observable atrophic features
- no evident atrophy or tissue thinning seen in the thalamus
- the caudate shows no notable changes suggestive of atrophy
- no appreciable degenerative or atrophic changes observed in the putamen
- amygdala maintains a normal appearance with no observable atrophic features
- no findings suggestive of atrophy are seen in the basal forebrain
- ventral dc demonstrates a healthy morphology without signs of atrophy
- no evident atrophy or tissue thinning seen in the accumbens
- hippocampus maintains a normal appearance with no observable atrophic features
For the cerebral cortex:
- parietal lobe appears within normal limits without apparent atrophy
- no observable atrophic changes in the limbic cortex
- no appreciable degenerative or atrophic changes observed in the insular cortex
- frontal lobe appears within normal limits without apparent atrophy
- mild atrophy of the right temporal lobe; the left temporal lobe is normal; focal volume loss observed in the following subregions: middle temporal gyrus (mild atrophy both left/right), temporal pole (mild atrophy both left/right), transverse temporal gyrus (no significant abnormality), planum temporale (no significant abnormality), planum polare (no significant abnormality), fusiform gyrus (no significant abnormality), inf. temporal gyrus (no significant abnormality) and sup. temporal gyrus (no significant abnormality)
- no clear atrophic alterations are visible in the occipital lobe
|
CN
|
FTLD_203322480_01082_MR_Sagittal_MP-Rage_br_raw_20230206133325499_I10181026
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- no clear enlargement or abnormal growth seen in the 3rd ventricle
- 4th ventricle maintains a typical volume without observable enlargement
- no findings suggestive of enlargement are seen in the inf. lateral ventricle
- no clear enlargement or abnormal growth seen in the lateral ventricle
- mild enlargement of the external csf
For the subcortical structures:
- thalamus demonstrates a healthy morphology without signs of atrophy
- hippocampus demonstrates a healthy morphology without signs of atrophy
- no observable atrophic changes in the caudate
- no clear atrophic alterations are visible in the accumbens
- no observable atrophic changes in the putamen
- basal forebrain demonstrates a healthy morphology without signs of atrophy
- mild atrophy of the right amygdala; the left amygdala is normal
- no evident atrophy or tissue thinning seen in the ventral dc
- pallidum appears preserved, with no observable tissue loss
For the cerebral cortex:
- no observable atrophic changes in the temporal lobe
- the limbic cortex shows no notable changes suggestive of atrophy
- parietal lobe appears preserved, with no observable tissue loss
- occipital lobe appears within normal limits without apparent atrophy
- mild bilateral atrophy of the frontal lobe; focal volume loss observed in the following subregions: triangular inf. frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), middle frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), anterior orbital gyrus (normal on the left and mild atrophy on the right), posterior orbital gyrus (no significant abnormality), subcallosal area (no significant abnormality), sup. frontal gyrus (no significant abnormality), gyrus rectus (no significant abnormality), medial frontal cortex (no significant abnormality), frontal pole (no significant abnormality), opercular inf. frontal gyrus (no significant abnormality), orbital inf. frontal gyrus (no significant abnormality), lateral orbital gyrus (no significant abnormality), medial orbital gyrus (no significant abnormality), precentral gyrus (no significant abnormality), precentral gyrus medial segment (no significant abnormality), sup. frontal gyrus medial segment (no significant abnormality) and supplementary motor cortex (no significant abnormality)
- mild atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: anterior insula (mild-to-moderate atrophy on the left and mild atrophy on the right), parietal operculum (mild atrophy on the left), posterior insula (no significant abnormality), central operculum (no significant abnormality) and frontal operculum (no significant abnormality)
|
CN
|
FTLD_203924869_01962_MR_Sagittal_MP-Rage_br_raw_20230206152530374_I10181383
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- accumbens appears within normal limits without apparent atrophy
- no evident atrophy or tissue thinning seen in the basal forebrain
- no clear atrophic alterations are visible in the thalamus
- mild-to-moderate atrophy of the left putamen and mild atrophy of the right putamen
- no clear atrophic alterations are visible in the ventral dc
- the caudate shows no notable changes suggestive of atrophy
- pallidum appears within normal limits without apparent atrophy
- no clear atrophic alterations are visible in the hippocampus
- amygdala demonstrates a healthy morphology without signs of atrophy
For the cerebral cortex:
- the occipital lobe shows no notable changes suggestive of atrophy
- frontal lobe demonstrates a healthy morphology without signs of atrophy
- no observable atrophic changes in the insular cortex
- limbic cortex maintains a normal appearance with no observable atrophic features
- no findings suggestive of atrophy are seen in the temporal lobe
- parietal lobe maintains a normal appearance with no observable atrophic features
For the ventricles:
- no findings suggestive of enlargement are seen in the external csf
- 4th ventricle maintains its expected proportions without signs of enlargement
- mild enlargement of the right inf. lateral ventricle; normal-to-mild enlargement of the left inf. lateral ventricle
- no clear enlargement or abnormal growth seen in the 3rd ventricle
- no clear enlargement or abnormal growth seen in the lateral ventricle
|
CN
|
ADNI_033_S_10144_MR_Accelerated_Sagittal_MPRAGE_MSV21_br_raw_20240710183736482_1_I10873175_dupl_1
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- mild atrophy of the right parietal lobe; the left parietal lobe is normal; focal volume loss observed in the following subregions: supramarginal gyrus (normal on the left and mild atrophy on the right), precuneus (normal on the left and mild atrophy on the right), postcentral gyrus (no significant abnormality), angular gyrus (no significant abnormality), postcentral gyrus medial segment (no significant abnormality) and sup. parietal lobule (no significant abnormality)
- mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: parahippocampal gyrus (no significant abnormality), entorhinal area (no significant abnormality), anterior cingulate gyrus (mild atrophy on the left and normal on the right), posterior cingulate gyrus (mild atrophy on the left and normal on the right) and middle cingulate gyrus (no significant abnormality)
- occipital lobe demonstrates a healthy morphology without signs of atrophy
- mild-to-moderate bilateral atrophy of the frontal lobe; focal volume loss observed in the following subregions: middle frontal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), triangular inf. frontal gyrus (mild atrophy on the right), sup. frontal gyrus (mild atrophy on the right), opercular inf. frontal gyrus (no significant abnormality), orbital inf. frontal gyrus (no significant abnormality), precentral gyrus (no significant abnormality), precentral gyrus medial segment (no significant abnormality), supplementary motor cortex (no significant abnormality), gyrus rectus (no significant abnormality), medial orbital gyrus (no significant abnormality), posterior orbital gyrus (no significant abnormality), subcallosal area (no significant abnormality), frontal pole (no significant abnormality), medial frontal cortex (no significant abnormality), anterior orbital gyrus (no significant abnormality), lateral orbital gyrus (no significant abnormality) and sup. frontal gyrus medial segment (no significant abnormality)
- mild bilateral atrophy of the insular cortex; focal volume loss observed in the following subregions: frontal operculum (mild atrophy both left/right), central operculum (mild atrophy on the left and normal-to-mild atrophy on the right), anterior insula (no significant abnormality), parietal operculum (no significant abnormality) and posterior insula (no significant abnormality)
- mild bilateral atrophy of the temporal lobe; focal volume loss observed in the following subregions: fusiform gyrus (mild atrophy both left/right), transverse temporal gyrus (mild atrophy both left/right), temporal pole (mild atrophy on the right), planum polare (no significant abnormality), sup. temporal gyrus (no significant abnormality), planum temporale (no significant abnormality), inf. temporal gyrus (no significant abnormality) and middle temporal gyrus (no significant abnormality)
For the ventricles:
- no observable enlargement of the lateral ventricle
- mild-to-moderate enlargement of the 4th ventricle
- 3rd ventricle maintains a typical volume without observable enlargement
- moderate bilateral enlargement of the inf. lateral ventricle
- no clear enlargement or abnormal growth seen in the external csf
For the subcortical structures:
- no evident atrophy or tissue thinning seen in the accumbens
- amygdala appears preserved, with no observable tissue loss
- thalamus appears preserved, with no observable tissue loss
- basal forebrain appears within normal limits without apparent atrophy
- the left hippocampus volume is borderline low
- the left hippocampus volume is borderline low
- putamen demonstrates a healthy morphology without signs of atrophy
- no clear atrophic alterations are visible in the pallidum
- no observable atrophic changes in the caudate
- ventral dc appears preserved, with no observable tissue loss
|
AD
|
FTLD_203961383_03386_MR_Accelerated_Sagittal_MPRAGE_TEST_br_raw_2_I10450649_dupl_10
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- mild-to-moderate atrophy of the right pallidum; the left pallidum is normal
- no findings suggestive of atrophy are seen in the basal forebrain
- moderate atrophy of the right putamen; normal-to-mild atrophy of the left putamen
- mild atrophy of the left hippocampus
- mild-to-moderate atrophy of the right hippocampus
- mild atrophy of the left caudate and moderate-to-severe atrophy of the right caudate
- mild-to-moderate atrophy of the left accumbens and severe atrophy of the right accumbens
- the thalamus shows no notable changes suggestive of atrophy
- severe bilateral atrophy of the amygdala
- no clear atrophic alterations are visible in the ventral dc
For the cerebral cortex:
- parietal lobe appears within normal limits without apparent atrophy
- frontal lobe maintains a normal appearance with no observable atrophic features
- moderate-to-severe atrophy of the right limbic cortex; the left limbic cortex is normal; focal volume loss observed in the following subregions: entorhinal area (mild atrophy on the left and mild-to-moderate atrophy on the right), parahippocampal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), anterior cingulate gyrus (normal on the left and moderate atrophy on the right), middle cingulate gyrus (mild atrophy on the right) and posterior cingulate gyrus (no significant abnormality)
- no findings suggestive of atrophy are seen in the occipital lobe
- mild-to-moderate atrophy of the right insular cortex; the left insular cortex is normal; focal volume loss observed in the following subregions: anterior insula (mild-to-moderate atrophy on the left and moderate atrophy on the right), parietal operculum (no significant abnormality), posterior insula (normal on the left and mild-to-moderate atrophy on the right), frontal operculum (no significant abnormality) and central operculum (no significant abnormality)
- moderate atrophy of the left temporal lobe and severe atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate-to-severe atrophy on the left and severe atrophy on the right), inf. temporal gyrus (moderate atrophy on the left and moderate-to-severe atrophy on the right), fusiform gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), middle temporal gyrus (normal on the left and moderate-to-severe atrophy on the right), sup. temporal gyrus (mild-to-moderate atrophy on the right), planum polare (normal on the left and mild atrophy on the right), planum temporale (no significant abnormality) and transverse temporal gyrus (no significant abnormality)
For the ventricles:
- moderate enlargement of the 3rd ventricle
- no appreciable enlargement noted in the 4th ventricle
- severe bilateral enlargement of the inf. lateral ventricle
- moderate-to-severe enlargement of the external csf
- mild enlargement of the right lateral ventricle; the left lateral ventricle is normal
|
SV
|
FTLD_203723261_03162_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10177101_dupl_14
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- mild-to-moderate enlargement of the external csf
- severe bilateral enlargement of the inf. lateral ventricle
- no observable enlargement of the 4th ventricle
- severe enlargement of the left lateral ventricle and mild-to-moderate enlargement of the right lateral ventricle
- no findings suggestive of enlargement are seen in the 3rd ventricle
For the subcortical structures:
- moderate-to-severe atrophy of the left hippocampus
- moderate-to-severe atrophy of the right hippocampus
- no evident atrophy or tissue thinning seen in the ventral dc
- moderate-to-severe atrophy of the left accumbens and mild-to-moderate atrophy of the right accumbens
- mild atrophy of the left thalamus; the right thalamus is normal
- moderate-to-severe atrophy of the left putamen and mild-to-moderate atrophy of the right putamen
- moderate atrophy of the left caudate and mild atrophy of the right caudate
- moderate atrophy of the left pallidum and mild-to-moderate atrophy of the right pallidum
- severe bilateral atrophy of the amygdala
- no findings suggestive of atrophy are seen in the basal forebrain
For the cerebral cortex:
- mild atrophy of the left frontal lobe; the right frontal lobe is normal; focal volume loss observed in the following subregions: orbital inf. frontal gyrus (no significant abnormality), gyrus rectus (mild-to-moderate atrophy on the left and normal on the right), triangular inf. frontal gyrus (mild atrophy on the right), precentral gyrus (no significant abnormality), frontal pole (no significant abnormality), medial frontal cortex (mild atrophy on the left), anterior orbital gyrus (mild atrophy on the left), medial orbital gyrus (no significant abnormality), supplementary motor cortex (no significant abnormality), sup. frontal gyrus (no significant abnormality), sup. frontal gyrus medial segment (no significant abnormality), opercular inf. frontal gyrus (no significant abnormality), middle frontal gyrus (no significant abnormality), lateral orbital gyrus (no significant abnormality), posterior orbital gyrus (no significant abnormality), precentral gyrus medial segment (no significant abnormality) and subcallosal area (no significant abnormality)
- no findings suggestive of atrophy are seen in the occipital lobe
- mild-to-moderate atrophy of the left insular cortex and mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right), posterior insula (moderate atrophy both left/right), central operculum (mild atrophy on the left), frontal operculum (no significant abnormality) and parietal operculum (no significant abnormality)
- severe atrophy of the left temporal lobe and mild-to-moderate atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate-to-severe atrophy on the left and moderate atrophy on the right), inf. temporal gyrus (moderate-to-severe atrophy on the left and mild atrophy on the right), middle temporal gyrus (moderate-to-severe atrophy on the left and normal-to-mild atrophy on the right), fusiform gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), planum polare (mild atrophy both left/right), sup. temporal gyrus (mild-to-moderate atrophy on the left), planum temporale (mild atrophy on the left) and transverse temporal gyrus (no significant abnormality)
- mild bilateral atrophy of the limbic cortex; focal volume loss observed in the following subregions: entorhinal area (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right), parahippocampal gyrus (mild-to-moderate atrophy on the left and normal on the right), anterior cingulate gyrus (no significant abnormality), middle cingulate gyrus (no significant abnormality) and posterior cingulate gyrus (no significant abnormality)
- parietal lobe demonstrates a healthy morphology without signs of atrophy
|
SV
|
FTLD_203723261_03162_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10177101_dupl_11
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- mild-to-moderate enlargement of the external csf
- 3rd ventricle maintains a typical volume without observable enlargement
- no observable enlargement of the 4th ventricle
- severe enlargement of the left lateral ventricle and mild-to-moderate enlargement of the right lateral ventricle
- severe bilateral enlargement of the inf. lateral ventricle
For the cerebral cortex:
- mild-to-moderate atrophy of the left insular cortex and mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right), posterior insula (moderate atrophy both left/right), central operculum (mild atrophy on the left), frontal operculum (no significant abnormality) and parietal operculum (no significant abnormality)
- severe atrophy of the left temporal lobe and mild-to-moderate atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate-to-severe atrophy on the left and moderate atrophy on the right), inf. temporal gyrus (moderate-to-severe atrophy on the left and mild atrophy on the right), middle temporal gyrus (moderate-to-severe atrophy on the left and normal-to-mild atrophy on the right), fusiform gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), planum polare (mild atrophy both left/right), sup. temporal gyrus (mild-to-moderate atrophy on the left), planum temporale (mild atrophy on the left) and transverse temporal gyrus (no significant abnormality)
- mild bilateral atrophy of the limbic cortex; focal volume loss observed in the following subregions: entorhinal area (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right), parahippocampal gyrus (mild-to-moderate atrophy on the left and normal on the right), anterior cingulate gyrus (no significant abnormality), middle cingulate gyrus (no significant abnormality) and posterior cingulate gyrus (no significant abnormality)
- no clear atrophic alterations are visible in the parietal lobe
- mild atrophy of the left frontal lobe; the right frontal lobe is normal; focal volume loss observed in the following subregions: orbital inf. frontal gyrus (no significant abnormality), gyrus rectus (mild-to-moderate atrophy on the left and normal on the right), triangular inf. frontal gyrus (mild atrophy on the right), precentral gyrus (no significant abnormality), frontal pole (no significant abnormality), medial frontal cortex (mild atrophy on the left), anterior orbital gyrus (mild atrophy on the left), medial orbital gyrus (no significant abnormality), supplementary motor cortex (no significant abnormality), sup. frontal gyrus (no significant abnormality), sup. frontal gyrus medial segment (no significant abnormality), opercular inf. frontal gyrus (no significant abnormality), middle frontal gyrus (no significant abnormality), lateral orbital gyrus (no significant abnormality), posterior orbital gyrus (no significant abnormality), precentral gyrus medial segment (no significant abnormality) and subcallosal area (no significant abnormality)
- no appreciable degenerative or atrophic changes observed in the occipital lobe
For the subcortical structures:
- severe bilateral atrophy of the amygdala
- moderate atrophy of the left pallidum and mild-to-moderate atrophy of the right pallidum
- moderate atrophy of the left caudate and mild atrophy of the right caudate
- mild atrophy of the left thalamus; the right thalamus is normal
- no evident atrophy or tissue thinning seen in the ventral dc
- basal forebrain appears within normal limits without apparent atrophy
- moderate-to-severe atrophy of the left hippocampus
- moderate-to-severe atrophy of the right hippocampus
- moderate-to-severe atrophy of the left accumbens and mild-to-moderate atrophy of the right accumbens
- moderate-to-severe atrophy of the left putamen and mild-to-moderate atrophy of the right putamen
|
SV
|
ADNI_053_S_5070_MR_MPRAGE_br_raw_20130201111516375_67_S181275_I357474_dupl_1
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- mild-to-moderate enlargement of the 3rd ventricle
- mild enlargement of the external csf
- moderate enlargement of the left inf. lateral ventricle and mild-to-moderate enlargement of the right inf. lateral ventricle
- mild enlargement of the 4th ventricle
- severe enlargement of the left lateral ventricle and moderate-to-severe enlargement of the right lateral ventricle
For the cerebral cortex:
- no findings suggestive of atrophy are seen in the frontal lobe
- mild atrophy of the left limbic cortex; normal-to-mild atrophy of the right limbic cortex; focal volume loss observed in the following subregions: middle cingulate gyrus (mild atrophy on the left and normal on the right), entorhinal area (no significant abnormality), parahippocampal gyrus (no significant abnormality), posterior cingulate gyrus (no significant abnormality) and anterior cingulate gyrus (no significant abnormality)
- mild bilateral atrophy of the temporal lobe; focal volume loss observed in the following subregions: middle temporal gyrus (mild atrophy both left/right), planum temporale (mild atrophy on the left and normal-to-mild atrophy on the right), sup. temporal gyrus (no significant abnormality), planum polare (no significant abnormality), temporal pole (no significant abnormality), fusiform gyrus (no significant abnormality), inf. temporal gyrus (no significant abnormality) and transverse temporal gyrus (no significant abnormality)
- mild-to-moderate atrophy of the left occipital lobe; the right occipital lobe is normal; focal volume loss observed in the following subregions: sup. occipital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), occipital fusiform gyrus (mild atrophy on the right), middle occipital gyrus (mild atrophy on the left and normal on the right), occipital pole (no significant abnormality), inf. occipital gyrus (mild atrophy on the left), calcarine cortex (no significant abnormality), cuneus (no significant abnormality) and lingual gyrus (no significant abnormality)
- mild-to-moderate atrophy of the left parietal lobe and mild atrophy of the right parietal lobe; focal volume loss observed in the following subregions: precuneus (mild atrophy both left/right), angular gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), supramarginal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), sup. parietal lobule (mild atrophy on the left and normal on the right), postcentral gyrus medial segment (no significant abnormality) and postcentral gyrus (no significant abnormality)
- mild bilateral atrophy of the insular cortex; focal volume loss observed in the following subregions: anterior insula (no significant abnormality), parietal operculum (normal on the left and mild atrophy on the right), central operculum (no significant abnormality), frontal operculum (no significant abnormality) and posterior insula (no significant abnormality)
For the subcortical structures:
- mild atrophy of the left thalamus; normal-to-mild atrophy of the right thalamus
- mild atrophy of the left caudate; normal-to-mild atrophy of the right caudate
- no clear atrophic alterations are visible in the amygdala
- mild-to-moderate atrophy of the left putamen; normal-to-mild atrophy of the right putamen
- the left hippocampus volume is borderline low
- the left hippocampus volume is borderline low
- mild atrophy of the left pallidum; normal-to-mild atrophy of the right pallidum
- no appreciable degenerative or atrophic changes observed in the ventral dc
- mild atrophy of the right accumbens; normal-to-mild atrophy of the left accumbens
- no evident atrophy or tissue thinning seen in the basal forebrain
|
AD
|
FTLD_203522833_02332_MR_Sagittal_MP-Rage_br_raw_20230209101231374_I10183395_dupl_1
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- the left hippocampus volume is borderline low
- mild bilateral atrophy of the pallidum
- mild-to-moderate bilateral atrophy of the thalamus
- mild bilateral atrophy of the caudate
- mild bilateral atrophy of the putamen
- mild bilateral atrophy of the ventral dc
- no appreciable degenerative or atrophic changes observed in the basal forebrain
- mild atrophy of the left amygdala; normal-to-mild atrophy of the right amygdala
- mild atrophy of the left accumbens; normal-to-mild atrophy of the right accumbens
For the ventricles:
- mild-to-moderate enlargement of the left inf. lateral ventricle and mild enlargement of the right inf. lateral ventricle
- mild-to-moderate enlargement of the external csf
- mild enlargement of the 4th ventricle
- mild enlargement of the left lateral ventricle and mild-to-moderate enlargement of the right lateral ventricle
- mild enlargement of the 3rd ventricle
For the cerebral cortex:
- no observable atrophic changes in the temporal lobe
- mild atrophy of the right limbic cortex; normal-to-mild atrophy of the left limbic cortex; focal volume loss observed in the following subregions: posterior cingulate gyrus (mild atrophy both left/right), parahippocampal gyrus (mild atrophy both left/right), entorhinal area (no significant abnormality), anterior cingulate gyrus (no significant abnormality) and middle cingulate gyrus (no significant abnormality)
- no evident atrophy or tissue thinning seen in the parietal lobe
- mild bilateral atrophy of the insular cortex; focal volume loss observed in the following subregions: central operculum (mild atrophy on the left and normal-to-mild atrophy on the right), posterior insula (normal on the left and mild atrophy on the right), anterior insula (no significant abnormality), frontal operculum (no significant abnormality) and parietal operculum (no significant abnormality)
- no evident atrophy or tissue thinning seen in the occipital lobe
- no observable atrophic changes in the frontal lobe
|
BV
|
ADNI_052_S_4885_MR_MT1__N3m_Br_20161014053352954_S498285_I782876_dupl_2
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- mild-to-moderate bilateral atrophy of the amygdala
- no clear atrophic alterations are visible in the basal forebrain
- mild-to-moderate atrophy of the left hippocampus
- mild-to-moderate atrophy of the right hippocampus
- no findings suggestive of atrophy are seen in the putamen
- thalamus appears preserved, with no observable tissue loss
- the ventral dc shows no notable changes suggestive of atrophy
- caudate appears within normal limits without apparent atrophy
- the pallidum shows no notable changes suggestive of atrophy
- accumbens demonstrates a healthy morphology without signs of atrophy
For the ventricles:
- 3rd ventricle maintains its expected proportions without signs of enlargement
- mild enlargement of the external csf
- mild enlargement of the 4th ventricle
- no appreciable enlargement noted in the lateral ventricle
- moderate-to-severe enlargement of the left inf. lateral ventricle and moderate enlargement of the right inf. lateral ventricle
For the cerebral cortex:
- no clear atrophic alterations are visible in the frontal lobe
- mild atrophy of the left temporal lobe and mild-to-moderate atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (mild atrophy both left/right), planum polare (no significant abnormality), inf. temporal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), middle temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), sup. temporal gyrus (no significant abnormality), planum temporale (no significant abnormality), fusiform gyrus (no significant abnormality) and transverse temporal gyrus (no significant abnormality)
- occipital lobe maintains a normal appearance with no observable atrophic features
- parietal lobe maintains a normal appearance with no observable atrophic features
- no clear atrophic alterations are visible in the insular cortex
- mild-to-moderate atrophy of the right limbic cortex; the left limbic cortex is normal; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild-to-moderate atrophy on the right), posterior cingulate gyrus (normal on the left and mild atrophy on the right), parahippocampal gyrus (normal on the left and mild atrophy on the right), entorhinal area (no significant abnormality) and middle cingulate gyrus (no significant abnormality)
|
AD
|
ADNI_130_S_4990_MR_MPRAGE_br_raw_20121029151935426_15_S172518_I342911_dupl_2
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- mild bilateral enlargement of the inf. lateral ventricle
- mild enlargement of the 3rd ventricle
- 4th ventricle maintains its expected proportions without signs of enlargement
- mild enlargement of the external csf
- mild enlargement of the left lateral ventricle and mild-to-moderate enlargement of the right lateral ventricle
For the subcortical structures:
- mild-to-moderate atrophy of the left accumbens and mild atrophy of the right accumbens
- mild bilateral atrophy of the amygdala
- mild bilateral atrophy of the putamen
- thalamus appears within normal limits without apparent atrophy
- no findings suggestive of atrophy are seen in the ventral dc
- mild atrophy of the left pallidum; normal-to-mild atrophy of the right pallidum
- mild atrophy of the left hippocampus
- mild atrophy of the right hippocampus
- no evident atrophy or tissue thinning seen in the basal forebrain
- mild atrophy of the right caudate; normal-to-mild atrophy of the left caudate
For the cerebral cortex:
- the insular cortex shows no notable changes suggestive of atrophy
- mild bilateral atrophy of the frontal lobe; focal volume loss observed in the following subregions: opercular inf. frontal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), medial orbital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), sup. frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), posterior orbital gyrus (mild atrophy on the right), lateral orbital gyrus (no significant abnormality), orbital inf. frontal gyrus (mild atrophy on the right), anterior orbital gyrus (no significant abnormality), precentral gyrus medial segment (no significant abnormality), frontal pole (no significant abnormality), gyrus rectus (no significant abnormality), middle frontal gyrus (no significant abnormality), medial frontal cortex (no significant abnormality), subcallosal area (no significant abnormality), triangular inf. frontal gyrus (no significant abnormality), precentral gyrus (no significant abnormality), sup. frontal gyrus medial segment (no significant abnormality) and supplementary motor cortex (no significant abnormality)
- no appreciable degenerative or atrophic changes observed in the temporal lobe
- mild atrophy of the right parietal lobe; normal-to-mild atrophy of the left parietal lobe; focal volume loss observed in the following subregions: supramarginal gyrus (mild atrophy on the left and normal on the right), angular gyrus (no significant abnormality), postcentral gyrus (no significant abnormality), precuneus (no significant abnormality), postcentral gyrus medial segment (no significant abnormality) and sup. parietal lobule (no significant abnormality)
- no evident atrophy or tissue thinning seen in the occipital lobe
- limbic cortex appears preserved, with no observable tissue loss
|
AD
|
ADNI_019_S_5012_MR_MPRAGE_br_raw_20121105133035688_113_S173252_I343916_dupl_3
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- no evident atrophy or tissue thinning seen in the basal forebrain
- no observable atrophic changes in the thalamus
- no findings suggestive of atrophy are seen in the caudate
- putamen appears within normal limits without apparent atrophy
- amygdala appears preserved, with no observable tissue loss
- accumbens appears preserved, with no observable tissue loss
- mild atrophy of the left hippocampus
- no observable atrophic changes in the ventral dc
- no clear atrophic alterations are visible in the pallidum
For the ventricles:
- no findings suggestive of enlargement are seen in the inf. lateral ventricle
- mild enlargement of the 4th ventricle
- mild enlargement of the right lateral ventricle; normal-to-mild enlargement of the left lateral ventricle
- mild enlargement of the 3rd ventricle
- mild enlargement of the external csf
For the cerebral cortex:
- mild bilateral atrophy of the temporal lobe; focal volume loss observed in the following subregions: sup. temporal gyrus (mild atrophy both left/right), fusiform gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), planum temporale (no significant abnormality), temporal pole (no significant abnormality), transverse temporal gyrus (no significant abnormality), planum polare (no significant abnormality), inf. temporal gyrus (no significant abnormality) and middle temporal gyrus (no significant abnormality)
- mild atrophy of the left parietal lobe; the right parietal lobe is normal; focal volume loss observed in the following subregions: postcentral gyrus medial segment (normal on the left and mild atrophy on the right), precuneus (no significant abnormality), sup. parietal lobule (mild atrophy on the left and normal on the right), postcentral gyrus (no significant abnormality), angular gyrus (no significant abnormality) and supramarginal gyrus (no significant abnormality)
- mild atrophy of the left frontal lobe; normal-to-mild atrophy of the right frontal lobe; focal volume loss observed in the following subregions: triangular inf. frontal gyrus (mild atrophy both left/right), medial orbital gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), precentral gyrus medial segment (normal on the left and mild-to-moderate atrophy on the right), orbital inf. frontal gyrus (mild-to-moderate atrophy on the left), supplementary motor cortex (no significant abnormality), gyrus rectus (no significant abnormality), medial frontal cortex (no significant abnormality), lateral orbital gyrus (no significant abnormality), precentral gyrus (no significant abnormality), opercular inf. frontal gyrus (no significant abnormality), anterior orbital gyrus (no significant abnormality), subcallosal area (no significant abnormality), sup. frontal gyrus (no significant abnormality), frontal pole (no significant abnormality), middle frontal gyrus (no significant abnormality), posterior orbital gyrus (no significant abnormality) and sup. frontal gyrus medial segment (no significant abnormality)
- no observable atrophic changes in the occipital lobe
- no findings suggestive of atrophy are seen in the limbic cortex
- mild bilateral atrophy of the insular cortex; focal volume loss observed in the following subregions: central operculum (mild atrophy both left/right), anterior insula (mild atrophy both left/right), posterior insula (no significant abnormality), frontal operculum (no significant abnormality) and parietal operculum (no significant abnormality)
|
AD
|
FTLD_203437946_02643_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178155_dupl_22
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- mild-to-moderate enlargement of the left lateral ventricle and mild enlargement of the right lateral ventricle
- mild enlargement of the 3rd ventricle
- moderate enlargement of the external csf
- no appreciable enlargement noted in the inf. lateral ventricle
- no observable enlargement of the 4th ventricle
For the cerebral cortex:
- no evident atrophy or tissue thinning seen in the occipital lobe
- mild atrophy of the right limbic cortex; the left limbic cortex is normal; focal volume loss observed in the following subregions: middle cingulate gyrus (no significant abnormality), anterior cingulate gyrus (mild atrophy on the right), entorhinal area (no significant abnormality), posterior cingulate gyrus (no significant abnormality) and parahippocampal gyrus (no significant abnormality)
- mild-to-moderate atrophy of the left parietal lobe and mild atrophy of the right parietal lobe; focal volume loss observed in the following subregions: angular gyrus (mild atrophy both left/right), postcentral gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), precuneus (no significant abnormality), postcentral gyrus medial segment (no significant abnormality), sup. parietal lobule (no significant abnormality) and supramarginal gyrus (no significant abnormality)
- mild bilateral atrophy of the temporal lobe; focal volume loss observed in the following subregions: fusiform gyrus (mild-to-moderate atrophy on the left and normal on the right), temporal pole (mild atrophy on the left and normal-to-mild atrophy on the right), planum temporale (no significant abnormality), sup. temporal gyrus (no significant abnormality), middle temporal gyrus (no significant abnormality), transverse temporal gyrus (no significant abnormality), planum polare (no significant abnormality) and inf. temporal gyrus (no significant abnormality)
- moderate atrophy of the left frontal lobe and mild-to-moderate atrophy of the right frontal lobe; focal volume loss observed in the following subregions: precentral gyrus (moderate-to-severe atrophy on the left and moderate atrophy on the right), subcallosal area (no significant abnormality), middle frontal gyrus (moderate atrophy on the left and normal on the right), gyrus rectus (no significant abnormality), opercular inf. frontal gyrus (mild atrophy both left/right), sup. frontal gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), sup. frontal gyrus medial segment (mild atrophy on the left and normal-to-mild atrophy on the right), precentral gyrus medial segment (mild atrophy on the left), supplementary motor cortex (normal on the left and mild atrophy on the right), lateral orbital gyrus (no significant abnormality), frontal pole (no significant abnormality), anterior orbital gyrus (no significant abnormality), orbital inf. frontal gyrus (no significant abnormality), triangular inf. frontal gyrus (no significant abnormality), medial frontal cortex (no significant abnormality), medial orbital gyrus (no significant abnormality) and posterior orbital gyrus (no significant abnormality)
- mild-to-moderate atrophy of the left insular cortex and mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: central operculum (mild atrophy both left/right), posterior insula (mild atrophy on the left and normal on the right), frontal operculum (no significant abnormality), anterior insula (no significant abnormality) and parietal operculum (no significant abnormality)
For the subcortical structures:
- ventral dc appears preserved, with no observable tissue loss
- mild atrophy of the left thalamus; normal-to-mild atrophy of the right thalamus
- mild-to-moderate atrophy of the left pallidum and mild atrophy of the right pallidum
- mild-to-moderate atrophy of the left putamen and mild atrophy of the right putamen
- no clear atrophic alterations are visible in the hippocampus
- mild bilateral atrophy of the amygdala
- the accumbens shows no notable changes suggestive of atrophy
- mild atrophy of the left caudate; normal-to-mild atrophy of the right caudate
- no evident atrophy or tissue thinning seen in the basal forebrain
|
PNFA
|
FTLD_203987322_03228_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10176938_dupl_22
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- mild-to-moderate enlargement of the left lateral ventricle and moderate enlargement of the right lateral ventricle
- no findings suggestive of enlargement are seen in the 4th ventricle
- mild-to-moderate enlargement of the 3rd ventricle
- severe bilateral enlargement of the inf. lateral ventricle
- mild-to-moderate enlargement of the external csf
For the cerebral cortex:
- limbic cortex appears within normal limits without apparent atrophy
- moderate atrophy of the left insular cortex; normal-to-mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: posterior insula (moderate atrophy on the left and mild atrophy on the right), anterior insula (moderate atrophy on the left), parietal operculum (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), central operculum (no significant abnormality) and frontal operculum (no significant abnormality)
- the occipital lobe shows no notable changes suggestive of atrophy
- severe atrophy of the left temporal lobe and moderate atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (severe atrophy on the left and moderate-to-severe atrophy on the right), inf. temporal gyrus (mild-to-moderate atrophy on the left and moderate atrophy on the right), fusiform gyrus (moderate atrophy on the left and mild atrophy on the right), middle temporal gyrus (moderate atrophy on the left), planum temporale (mild atrophy both left/right), planum polare (no significant abnormality), sup. temporal gyrus (mild atrophy on the left) and transverse temporal gyrus (no significant abnormality)
- parietal lobe demonstrates a healthy morphology without signs of atrophy
- no findings suggestive of atrophy are seen in the frontal lobe
For the subcortical structures:
- moderate atrophy of the left hippocampus
- mild atrophy of the right hippocampus
- moderate-to-severe atrophy of the left accumbens and moderate atrophy of the right accumbens
- caudate appears within normal limits without apparent atrophy
- mild-to-moderate atrophy of the left putamen; the right putamen is normal
- mild atrophy of the left thalamus; the right thalamus is normal
- severe bilateral atrophy of the amygdala
- mild atrophy of the left pallidum; the right pallidum is normal
- ventral dc maintains a normal appearance with no observable atrophic features
- basal forebrain appears preserved, with no observable tissue loss
|
SV
|
FTLD_203419597_02791_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177849_dupl_3
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- mild-to-moderate atrophy of the left temporal lobe and severe atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate atrophy on the left and moderate-to-severe atrophy on the right), fusiform gyrus (mild-to-moderate atrophy on the left and moderate-to-severe atrophy on the right), middle temporal gyrus (normal-to-mild atrophy on the left and severe atrophy on the right), inf. temporal gyrus (normal on the left and moderate-to-severe atrophy on the right), planum polare (normal on the left and moderate atrophy on the right), sup. temporal gyrus (no significant abnormality), planum temporale (no significant abnormality) and transverse temporal gyrus (no significant abnormality)
- moderate atrophy of the right occipital lobe; the left occipital lobe is normal; focal volume loss observed in the following subregions: calcarine cortex (mild-to-moderate atrophy both left/right), middle occipital gyrus (mild-to-moderate atrophy on the right), cuneus (no significant abnormality), inf. occipital gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), sup. occipital gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), occipital pole (normal on the left and mild atrophy on the right), occipital fusiform gyrus (mild atrophy on the right) and lingual gyrus (no significant abnormality)
- mild atrophy of the left limbic cortex and mild-to-moderate atrophy of the right limbic cortex; focal volume loss observed in the following subregions: entorhinal area (moderate atrophy on the left and severe atrophy on the right), parahippocampal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), anterior cingulate gyrus (mild atrophy both left/right), middle cingulate gyrus (no significant abnormality) and posterior cingulate gyrus (no significant abnormality)
- mild atrophy of the right frontal lobe; the left frontal lobe is normal; focal volume loss observed in the following subregions: posterior orbital gyrus (mild atrophy both left/right), frontal pole (no significant abnormality), orbital inf. frontal gyrus (no significant abnormality), medial orbital gyrus (normal on the left and mild atrophy on the right), gyrus rectus (mild atrophy on the right), precentral gyrus medial segment (no significant abnormality), triangular inf. frontal gyrus (mild atrophy on the right), middle frontal gyrus (no significant abnormality), opercular inf. frontal gyrus (no significant abnormality), lateral orbital gyrus (no significant abnormality), medial frontal cortex (no significant abnormality), anterior orbital gyrus (no significant abnormality), subcallosal area (no significant abnormality), supplementary motor cortex (no significant abnormality), precentral gyrus (no significant abnormality), sup. frontal gyrus (no significant abnormality) and sup. frontal gyrus medial segment (no significant abnormality)
- mild-to-moderate atrophy of the left insular cortex and severe atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (severe atrophy both left/right), posterior insula (mild atrophy on the left and severe atrophy on the right), parietal operculum (mild-to-moderate atrophy on the right), central operculum (no significant abnormality) and frontal operculum (mild atrophy on the right)
- parietal lobe demonstrates a healthy morphology without signs of atrophy
For the subcortical structures:
- moderate-to-severe atrophy of the left accumbens and severe atrophy of the right accumbens
- mild atrophy of the left pallidum and moderate atrophy of the right pallidum
- moderate atrophy of the left putamen and severe atrophy of the right putamen
- moderate atrophy of the left caudate and moderate-to-severe atrophy of the right caudate
- ventral dc appears preserved, with no observable tissue loss
- mild atrophy of the left thalamus and mild-to-moderate atrophy of the right thalamus
- no appreciable degenerative or atrophic changes observed in the basal forebrain
- moderate-to-severe atrophy of the left hippocampus
- severe atrophy of the right hippocampus
- severe bilateral atrophy of the amygdala
For the ventricles:
- no clear enlargement or abnormal growth seen in the 4th ventricle
- mild-to-moderate enlargement of the external csf
- severe bilateral enlargement of the lateral ventricle
- moderate-to-severe enlargement of the 3rd ventricle
- severe enlargement of the left inf. lateral ventricle and moderate enlargement of the right inf. lateral ventricle
|
SV
|
FTLD_203107786_02680_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178191_dupl_6
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- severe bilateral atrophy of the amygdala
- the basal forebrain shows no notable changes suggestive of atrophy
- severe bilateral atrophy of the accumbens
- ventral dc appears preserved, with no observable tissue loss
- severe atrophy of the left hippocampus
- severe atrophy of the right hippocampus
- moderate atrophy of the left putamen and moderate-to-severe atrophy of the right putamen
- moderate-to-severe bilateral atrophy of the caudate
- mild-to-moderate bilateral atrophy of the pallidum
- mild bilateral atrophy of the thalamus
For the cerebral cortex:
- mild atrophy of the left limbic cortex and mild-to-moderate atrophy of the right limbic cortex; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild-to-moderate atrophy on the left and moderate atrophy on the right), entorhinal area (mild-to-moderate atrophy on the left and mild atrophy on the right), parahippocampal gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), posterior cingulate gyrus (no significant abnormality) and middle cingulate gyrus (no significant abnormality)
- moderate-to-severe bilateral atrophy of the insular cortex; focal volume loss observed in the following subregions: anterior insula (severe atrophy both left/right), posterior insula (moderate atrophy both left/right), central operculum (normal-to-mild atrophy on the left and mild atrophy on the right), parietal operculum (normal-to-mild atrophy on the left and mild atrophy on the right) and frontal operculum (no significant abnormality)
- occipital lobe demonstrates a healthy morphology without signs of atrophy
- no observable atrophic changes in the parietal lobe
- mild-to-moderate bilateral atrophy of the frontal lobe; focal volume loss observed in the following subregions: gyrus rectus (mild-to-moderate atrophy on the left and moderate atrophy on the right), medial orbital gyrus (moderate atrophy on the left and mild-to-moderate atrophy on the right), posterior orbital gyrus (moderate atrophy on the left and mild atrophy on the right), medial frontal cortex (mild atrophy both left/right), orbital inf. frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), anterior orbital gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), sup. frontal gyrus medial segment (mild atrophy on the left and normal-to-mild atrophy on the right), middle frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), precentral gyrus (no significant abnormality), triangular inf. frontal gyrus (normal on the left and mild atrophy on the right), subcallosal area (no significant abnormality), supplementary motor cortex (no significant abnormality), opercular inf. frontal gyrus (no significant abnormality), precentral gyrus medial segment (no significant abnormality), sup. frontal gyrus (no significant abnormality), frontal pole (no significant abnormality) and lateral orbital gyrus (no significant abnormality)
- moderate-to-severe bilateral atrophy of the temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate atrophy on the left and moderate-to-severe atrophy on the right), inf. temporal gyrus (mild-to-moderate atrophy both left/right), middle temporal gyrus (mild-to-moderate atrophy both left/right), fusiform gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), sup. temporal gyrus (no significant abnormality), transverse temporal gyrus (no significant abnormality), planum polare (no significant abnormality) and planum temporale (no significant abnormality)
For the ventricles:
- mild enlargement of the 4th ventricle
- moderate enlargement of the external csf
- moderate enlargement of the left lateral ventricle and moderate-to-severe enlargement of the right lateral ventricle
- severe bilateral enlargement of the inf. lateral ventricle
- mild enlargement of the 3rd ventricle
|
BV
|
FTLD_203447418_03814_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10451166_dupl_21
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- the pallidum shows no notable changes suggestive of atrophy
- no findings suggestive of atrophy are seen in the basal forebrain
- no observable atrophic changes in the thalamus
- mild atrophy of the left accumbens; normal-to-mild atrophy of the right accumbens
- caudate appears preserved, with no observable tissue loss
- moderate atrophy of the left hippocampus
- mild atrophy of the right hippocampus
- mild atrophy of the left putamen; the right putamen is normal
- ventral dc appears within normal limits without apparent atrophy
- severe atrophy of the left amygdala and mild-to-moderate atrophy of the right amygdala
For the cerebral cortex:
- the occipital lobe shows no notable changes suggestive of atrophy
- frontal lobe appears within normal limits without apparent atrophy
- no observable atrophic changes in the parietal lobe
- mild atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: parietal operculum (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), posterior insula (mild atrophy on the left), central operculum (mild atrophy on the left and normal on the right), anterior insula (no significant abnormality) and frontal operculum (no significant abnormality)
- severe atrophy of the left temporal lobe and moderate-to-severe atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right), middle temporal gyrus (moderate-to-severe atrophy on the left and mild atrophy on the right), inf. temporal gyrus (moderate atrophy on the left and mild-to-moderate atrophy on the right), fusiform gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), planum temporale (mild atrophy on the left and mild-to-moderate atrophy on the right), sup. temporal gyrus (mild atrophy on the left and normal on the right), planum polare (no significant abnormality) and transverse temporal gyrus (no significant abnormality)
- no observable atrophic changes in the limbic cortex
For the ventricles:
- severe enlargement of the left inf. lateral ventricle and moderate-to-severe enlargement of the right inf. lateral ventricle
- no appreciable enlargement noted in the 3rd ventricle
- no appreciable enlargement noted in the external csf
- no clear enlargement or abnormal growth seen in the 4th ventricle
- mild bilateral enlargement of the lateral ventricle
|
SV
|
FTLD_203875531_03137_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10450288_dupl_3
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- no appreciable enlargement noted in the 4th ventricle
- severe enlargement of the left inf. lateral ventricle; the right inf. lateral ventricle is normal
- the 3rd ventricle shows no notable changes suggestive of enlargement
- the external csf shows no notable changes suggestive of enlargement
- lateral ventricle maintains a typical volume without observable enlargement
For the cerebral cortex:
- the frontal lobe shows no notable changes suggestive of atrophy
- no findings suggestive of atrophy are seen in the occipital lobe
- moderate atrophy of the left temporal lobe; normal-to-mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: planum temporale (no significant abnormality), temporal pole (moderate-to-severe atrophy on the left), fusiform gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), inf. temporal gyrus (no significant abnormality), planum polare (mild atrophy on the left and normal on the right), transverse temporal gyrus (no significant abnormality), middle temporal gyrus (mild atrophy on the left and normal on the right) and sup. temporal gyrus (no significant abnormality)
- insular cortex maintains a normal appearance with no observable atrophic features
- no appreciable degenerative or atrophic changes observed in the limbic cortex
- the parietal lobe shows no notable changes suggestive of atrophy
For the subcortical structures:
- severe atrophy of the left amygdala; the right amygdala is normal
- the left hippocampus volume is borderline low
- no appreciable degenerative or atrophic changes observed in the basal forebrain
- mild-to-moderate atrophy of the left pallidum; normal-to-mild atrophy of the right pallidum
- accumbens appears preserved, with no observable tissue loss
- no evident atrophy or tissue thinning seen in the ventral dc
- no evident atrophy or tissue thinning seen in the putamen
- thalamus demonstrates a healthy morphology without signs of atrophy
- caudate appears preserved, with no observable tissue loss
|
SV
|
ADNI_116_S_4338_MR_MPRAGE_br_raw_20111107090101281_142_S128214_I264968_dupl_1
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- mild atrophy of the left limbic cortex and mild-to-moderate atrophy of the right limbic cortex; focal volume loss observed in the following subregions: anterior cingulate gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), parahippocampal gyrus (mild atrophy both left/right), entorhinal area (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), posterior cingulate gyrus (no significant abnormality) and middle cingulate gyrus (no significant abnormality)
- no evident atrophy or tissue thinning seen in the occipital lobe
- mild-to-moderate atrophy of the right temporal lobe; normal-to-mild atrophy of the left temporal lobe; focal volume loss observed in the following subregions: planum polare (mild atrophy both left/right), planum temporale (no significant abnormality), fusiform gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), inf. temporal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), temporal pole (normal on the left and mild-to-moderate atrophy on the right), middle temporal gyrus (normal on the left and mild atrophy on the right), sup. temporal gyrus (no significant abnormality) and transverse temporal gyrus (no significant abnormality)
- mild atrophy of the left insular cortex; normal-to-mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate atrophy on the left and moderate-to-severe atrophy on the right), posterior insula (mild-to-moderate atrophy on the left and mild atrophy on the right), frontal operculum (no significant abnormality), parietal operculum (no significant abnormality) and central operculum (no significant abnormality)
- frontal lobe appears preserved, with no observable tissue loss
- no findings suggestive of atrophy are seen in the parietal lobe
For the subcortical structures:
- mild-to-moderate bilateral atrophy of the putamen
- mild atrophy of the left hippocampus
- mild atrophy of the right hippocampus
- mild atrophy of the left pallidum and mild-to-moderate atrophy of the right pallidum
- no observable atrophic changes in the basal forebrain
- mild bilateral atrophy of the thalamus
- mild atrophy of the left accumbens and mild-to-moderate atrophy of the right accumbens
- mild atrophy of the left caudate; normal-to-mild atrophy of the right caudate
- mild atrophy of the right ventral dc; normal-to-mild atrophy of the left ventral dc
- moderate-to-severe atrophy of the left amygdala and moderate atrophy of the right amygdala
For the ventricles:
- no appreciable enlargement noted in the 4th ventricle
- mild enlargement of the external csf
- mild bilateral enlargement of the lateral ventricle
- mild enlargement of the 3rd ventricle
- severe bilateral enlargement of the inf. lateral ventricle
|
AD
|
ADNI_130_S_4352_MR_MPRAGE_br_raw_20111121102623843_152_S130237_I267711
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- occipital lobe appears within normal limits without apparent atrophy
- frontal lobe maintains a normal appearance with no observable atrophic features
- parietal lobe maintains a normal appearance with no observable atrophic features
- no clear atrophic alterations are visible in the insular cortex
- no appreciable degenerative or atrophic changes observed in the temporal lobe
- mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: middle cingulate gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), anterior cingulate gyrus (normal on the left and mild atrophy on the right), parahippocampal gyrus (no significant abnormality), entorhinal area (no significant abnormality) and posterior cingulate gyrus (no significant abnormality)
For the ventricles:
- no clear enlargement or abnormal growth seen in the 4th ventricle
- inf. lateral ventricle appears within normal size limits with no apparent enlargement
- lateral ventricle maintains a typical volume without observable enlargement
- mild enlargement of the external csf
- no clear enlargement or abnormal growth seen in the 3rd ventricle
For the subcortical structures:
- no appreciable degenerative or atrophic changes observed in the basal forebrain
- amygdala appears within normal limits without apparent atrophy
- no observable atrophic changes in the hippocampus
- no clear atrophic alterations are visible in the accumbens
- no clear atrophic alterations are visible in the thalamus
- no appreciable degenerative or atrophic changes observed in the putamen
- mild bilateral atrophy of the caudate
- no observable atrophic changes in the ventral dc
- no clear atrophic alterations are visible in the pallidum
|
CN
|
FTLD_203196400_02009_MR_Sagittal_MP-Rage_br_raw_20230209094406847_I10183255_dupl_6
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy both left/right), posterior cingulate gyrus (no significant abnormality), parahippocampal gyrus (mild atrophy on the left and normal on the right), entorhinal area (no significant abnormality) and middle cingulate gyrus (no significant abnormality)
- parietal lobe demonstrates a healthy morphology without signs of atrophy
- the occipital lobe shows no notable changes suggestive of atrophy
- mild atrophy of the left frontal lobe and mild-to-moderate atrophy of the right frontal lobe; focal volume loss observed in the following subregions: posterior orbital gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), opercular inf. frontal gyrus (mild atrophy both left/right), orbital inf. frontal gyrus (mild atrophy both left/right), middle frontal gyrus (mild atrophy both left/right), gyrus rectus (mild atrophy on the left and normal-to-mild atrophy on the right), triangular inf. frontal gyrus (normal on the left and mild atrophy on the right), lateral orbital gyrus (no significant abnormality), precentral gyrus (mild atrophy on the left and normal on the right), precentral gyrus medial segment (mild atrophy on the left and normal on the right), sup. frontal gyrus medial segment (normal on the left and mild atrophy on the right), supplementary motor cortex (no significant abnormality), medial orbital gyrus (no significant abnormality), medial frontal cortex (no significant abnormality), frontal pole (no significant abnormality), anterior orbital gyrus (no significant abnormality), subcallosal area (no significant abnormality) and sup. frontal gyrus (no significant abnormality)
- mild-to-moderate atrophy of the left insular cortex and moderate atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (mild-to-moderate atrophy both left/right), central operculum (mild-to-moderate atrophy both left/right), posterior insula (normal on the left and mild-to-moderate atrophy on the right), frontal operculum (no significant abnormality) and parietal operculum (no significant abnormality)
- mild bilateral atrophy of the temporal lobe; focal volume loss observed in the following subregions: transverse temporal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), temporal pole (normal-to-mild atrophy on the left and mild atrophy on the right), fusiform gyrus (mild atrophy on the left and normal on the right), planum temporale (normal on the left and mild atrophy on the right), middle temporal gyrus (no significant abnormality), sup. temporal gyrus (no significant abnormality), planum polare (no significant abnormality) and inf. temporal gyrus (no significant abnormality)
For the subcortical structures:
- no appreciable degenerative or atrophic changes observed in the basal forebrain
- moderate-to-severe bilateral atrophy of the accumbens
- severe bilateral atrophy of the caudate
- mild-to-moderate bilateral atrophy of the thalamus
- moderate-to-severe atrophy of the left putamen and moderate atrophy of the right putamen
- mild bilateral atrophy of the amygdala
- moderate bilateral atrophy of the pallidum
- mild bilateral atrophy of the ventral dc
- the left hippocampus volume is borderline low
- the left hippocampus volume is borderline low
For the ventricles:
- moderate enlargement of the external csf
- moderate-to-severe enlargement of the 3rd ventricle
- severe bilateral enlargement of the inf. lateral ventricle
- severe bilateral enlargement of the lateral ventricle
- severe enlargement of the 4th ventricle
|
BV
|
FTLD_203197555_03559_MR_Accelerated_Sagittal_MPRAGE_br_raw_20241_I11047584_dupl_2
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- mild atrophy of the right thalamus; normal-to-mild atrophy of the left thalamus
- no clear atrophic alterations are visible in the amygdala
- moderate atrophy of the left accumbens and mild-to-moderate atrophy of the right accumbens
- hippocampus appears within normal limits without apparent atrophy
- basal forebrain appears within normal limits without apparent atrophy
- moderate-to-severe atrophy of the left putamen and mild-to-moderate atrophy of the right putamen
- mild-to-moderate atrophy of the left pallidum and moderate atrophy of the right pallidum
- ventral dc appears within normal limits without apparent atrophy
- mild-to-moderate atrophy of the left caudate and moderate-to-severe atrophy of the right caudate
For the ventricles:
- moderate enlargement of the 3rd ventricle
- mild-to-moderate enlargement of the left inf. lateral ventricle and mild enlargement of the right inf. lateral ventricle
- 4th ventricle appears within normal size limits with no apparent enlargement
- mild-to-moderate enlargement of the external csf
- mild bilateral enlargement of the lateral ventricle
For the cerebral cortex:
- moderate atrophy of the left frontal lobe and moderate-to-severe atrophy of the right frontal lobe; focal volume loss observed in the following subregions: middle frontal gyrus (moderate atrophy on the left and moderate-to-severe atrophy on the right), anterior orbital gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), opercular inf. frontal gyrus (mild atrophy both left/right), medial orbital gyrus (mild atrophy both left/right), subcallosal area (no significant abnormality), sup. frontal gyrus medial segment (normal on the left and mild-to-moderate atrophy on the right), gyrus rectus (mild atrophy on the left and normal on the right), precentral gyrus (normal on the left and mild atrophy on the right), frontal pole (no significant abnormality), posterior orbital gyrus (mild atrophy on the right), sup. frontal gyrus (no significant abnormality), precentral gyrus medial segment (no significant abnormality), orbital inf. frontal gyrus (no significant abnormality), medial frontal cortex (no significant abnormality), triangular inf. frontal gyrus (no significant abnormality), lateral orbital gyrus (no significant abnormality) and supplementary motor cortex (no significant abnormality)
- no appreciable degenerative or atrophic changes observed in the limbic cortex
- insular cortex maintains a normal appearance with no observable atrophic features
- parietal lobe demonstrates a healthy morphology without signs of atrophy
- mild bilateral atrophy of the temporal lobe; focal volume loss observed in the following subregions: fusiform gyrus (mild atrophy both left/right), transverse temporal gyrus (no significant abnormality), middle temporal gyrus (mild atrophy on the left and normal on the right), planum temporale (no significant abnormality), sup. temporal gyrus (normal on the left and mild atrophy on the right), temporal pole (no significant abnormality), planum polare (no significant abnormality) and inf. temporal gyrus (no significant abnormality)
- occipital lobe appears within normal limits without apparent atrophy
|
BV
|
FTLD_203163034_02436_MR_Sagittal_MP-Rage_br_raw_20230209101942649_I10183429_dupl_18
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- no appreciable degenerative or atrophic changes observed in the insular cortex
- no clear atrophic alterations are visible in the limbic cortex
- temporal lobe appears within normal limits without apparent atrophy
- mild atrophy of the left frontal lobe; normal-to-mild atrophy of the right frontal lobe; focal volume loss observed in the following subregions: opercular inf. frontal gyrus (mild atrophy both left/right), posterior orbital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), sup. frontal gyrus medial segment (no significant abnormality), supplementary motor cortex (mild-to-moderate atrophy on the left and normal on the right), gyrus rectus (mild atrophy on the left and normal on the right), middle frontal gyrus (no significant abnormality), orbital inf. frontal gyrus (no significant abnormality), triangular inf. frontal gyrus (mild atrophy on the left and normal on the right), sup. frontal gyrus (no significant abnormality), anterior orbital gyrus (no significant abnormality), lateral orbital gyrus (no significant abnormality), subcallosal area (no significant abnormality), frontal pole (no significant abnormality), medial frontal cortex (no significant abnormality), medial orbital gyrus (no significant abnormality), precentral gyrus (no significant abnormality) and precentral gyrus medial segment (no significant abnormality)
- no observable atrophic changes in the parietal lobe
- occipital lobe appears within normal limits without apparent atrophy
For the subcortical structures:
- mild atrophy of the left putamen; normal-to-mild atrophy of the right putamen
- mild bilateral atrophy of the caudate
- no observable atrophic changes in the hippocampus
- no clear atrophic alterations are visible in the thalamus
- mild-to-moderate atrophy of the left accumbens and mild atrophy of the right accumbens
- mild bilateral atrophy of the pallidum
- no clear atrophic alterations are visible in the ventral dc
- basal forebrain demonstrates a healthy morphology without signs of atrophy
- mild atrophy of the left amygdala; the right amygdala is normal
For the ventricles:
- the 3rd ventricle shows no notable changes suggestive of enlargement
- inf. lateral ventricle appears to be of normal dimensions, with no observable increase in size
- 4th ventricle maintains a typical volume without observable enlargement
- no observable enlargement of the lateral ventricle
- mild-to-moderate enlargement of the external csf
|
PNFA
|
ADNI_012_S_5213_MR_MPRAGE_SENSE2__br_raw_20130722150031094_1_S196004_I381908
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- frontal lobe maintains a normal appearance with no observable atrophic features
- no clear atrophic alterations are visible in the insular cortex
- no appreciable degenerative or atrophic changes observed in the parietal lobe
- no findings suggestive of atrophy are seen in the occipital lobe
- temporal lobe appears preserved, with no observable tissue loss
- limbic cortex appears preserved, with no observable tissue loss
For the subcortical structures:
- putamen demonstrates a healthy morphology without signs of atrophy
- amygdala appears preserved, with no observable tissue loss
- hippocampus appears preserved, with no observable tissue loss
- caudate maintains a normal appearance with no observable atrophic features
- ventral dc appears within normal limits without apparent atrophy
- mild-to-moderate atrophy of the right basal forebrain; normal-to-mild atrophy of the left basal forebrain
- no appreciable degenerative or atrophic changes observed in the pallidum
- thalamus maintains a normal appearance with no observable atrophic features
- accumbens appears preserved, with no observable tissue loss
For the ventricles:
- no clear enlargement or abnormal growth seen in the 4th ventricle
- no evident size increase noted in the 3rd ventricle
- external csf appears within normal size limits with no apparent enlargement
- lateral ventricle maintains its expected proportions without signs of enlargement
- inf. lateral ventricle maintains its expected proportions without signs of enlargement
|
CN
|
FTLD_203656054_03455_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10450768_dupl_9
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- no evident atrophy or tissue thinning seen in the parietal lobe
- moderate-to-severe atrophy of the left temporal lobe and severe atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate atrophy on the left and moderate-to-severe atrophy on the right), middle temporal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), inf. temporal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), planum temporale (mild atrophy both left/right), sup. temporal gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), transverse temporal gyrus (mild atrophy both left/right), fusiform gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right) and planum polare (normal-to-mild atrophy on the left and mild atrophy on the right)
- no clear atrophic alterations are visible in the frontal lobe
- no evident atrophy or tissue thinning seen in the limbic cortex
- no evident atrophy or tissue thinning seen in the occipital lobe
- moderate atrophy of the left insular cortex and moderate-to-severe atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate atrophy on the left and moderate-to-severe atrophy on the right), posterior insula (mild atrophy on the left and mild-to-moderate atrophy on the right), parietal operculum (mild atrophy both left/right), frontal operculum (normal-to-mild atrophy on the left and mild atrophy on the right) and central operculum (no significant abnormality)
For the ventricles:
- severe bilateral enlargement of the inf. lateral ventricle
- mild enlargement of the external csf
- mild enlargement of the 3rd ventricle
- mild enlargement of the right lateral ventricle; normal-to-mild enlargement of the left lateral ventricle
- the 4th ventricle shows no notable changes suggestive of enlargement
For the subcortical structures:
- no clear atrophic alterations are visible in the putamen
- no clear atrophic alterations are visible in the caudate
- no observable atrophic changes in the pallidum
- no findings suggestive of atrophy are seen in the ventral dc
- mild atrophy of the right accumbens; the left accumbens is normal
- mild-to-moderate atrophy of the left hippocampus
- moderate-to-severe atrophy of the right hippocampus
- the basal forebrain shows no notable changes suggestive of atrophy
- severe bilateral atrophy of the amygdala
- mild bilateral atrophy of the thalamus
|
SV
|
FTLD_203995405_01509_MR_Sagittal_MP-Rage_br_raw_20230206173212581_I10182118_dupl_1
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- mild bilateral atrophy of the pallidum
- mild-to-moderate bilateral atrophy of the putamen
- severe bilateral atrophy of the amygdala
- moderate-to-severe bilateral atrophy of the accumbens
- no appreciable degenerative or atrophic changes observed in the basal forebrain
- mild bilateral atrophy of the thalamus
- moderate-to-severe atrophy of the left hippocampus
- moderate-to-severe atrophy of the right hippocampus
- no observable atrophic changes in the ventral dc
- mild-to-moderate atrophy of the left caudate and moderate atrophy of the right caudate
For the ventricles:
- moderate bilateral enlargement of the inf. lateral ventricle
- mild enlargement of the 3rd ventricle
- severe enlargement of the external csf
- mild enlargement of the left lateral ventricle; normal-to-mild enlargement of the right lateral ventricle
- 4th ventricle maintains a typical volume without observable enlargement
For the cerebral cortex:
- moderate atrophy of the left limbic cortex and moderate-to-severe atrophy of the right limbic cortex; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild-to-moderate atrophy on the left and moderate atrophy on the right), entorhinal area (mild-to-moderate atrophy both left/right), parahippocampal gyrus (mild-to-moderate atrophy both left/right), middle cingulate gyrus (mild atrophy on the right) and posterior cingulate gyrus (no significant abnormality)
- mild atrophy of the left insular cortex and mild-to-moderate atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate-to-severe atrophy on the left and severe atrophy on the right), posterior insula (mild-to-moderate atrophy both left/right), central operculum (no significant abnormality), frontal operculum (no significant abnormality) and parietal operculum (no significant abnormality)
- no evident atrophy or tissue thinning seen in the parietal lobe
- mild-to-moderate bilateral atrophy of the frontal lobe; focal volume loss observed in the following subregions: frontal pole (mild atrophy on the left and mild-to-moderate atrophy on the right), medial frontal cortex (mild atrophy on the left and mild-to-moderate atrophy on the right), medial orbital gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), posterior orbital gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), gyrus rectus (mild atrophy both left/right), sup. frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), middle frontal gyrus (mild-to-moderate atrophy on the left), lateral orbital gyrus (mild atrophy on the right), subcallosal area (no significant abnormality), supplementary motor cortex (no significant abnormality), orbital inf. frontal gyrus (no significant abnormality), precentral gyrus medial segment (no significant abnormality), opercular inf. frontal gyrus (no significant abnormality), triangular inf. frontal gyrus (no significant abnormality), anterior orbital gyrus (no significant abnormality), precentral gyrus (no significant abnormality) and sup. frontal gyrus medial segment (no significant abnormality)
- no appreciable degenerative or atrophic changes observed in the occipital lobe
- severe bilateral atrophy of the temporal lobe; focal volume loss observed in the following subregions: temporal pole (severe atrophy both left/right), inf. temporal gyrus (mild-to-moderate atrophy on the left and moderate atrophy on the right), middle temporal gyrus (mild atrophy on the left and moderate-to-severe atrophy on the right), fusiform gyrus (mild-to-moderate atrophy both left/right), planum polare (mild-to-moderate atrophy on the left and mild atrophy on the right), sup. temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), transverse temporal gyrus (no significant abnormality) and planum temporale (no significant abnormality)
|
BV
|
ADNI_023_S_5120_MR_MPRAGE_GRAPPA2_br_raw_20130515153208092_97_S189446_I372410_dupl_2
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- 3rd ventricle maintains a typical volume without observable enlargement
- the 4th ventricle shows no notable changes suggestive of enlargement
- no appreciable enlargement noted in the inf. lateral ventricle
- no evident size increase noted in the external csf
- no evident size increase noted in the lateral ventricle
For the subcortical structures:
- amygdala maintains a normal appearance with no observable atrophic features
- mild atrophy of the right basal forebrain; the left basal forebrain is normal
- mild atrophy of the right putamen; normal-to-mild atrophy of the left putamen
- no appreciable degenerative or atrophic changes observed in the ventral dc
- pallidum appears within normal limits without apparent atrophy
- no clear atrophic alterations are visible in the thalamus
- hippocampus maintains a normal appearance with no observable atrophic features
- no findings suggestive of atrophy are seen in the caudate
- accumbens maintains a normal appearance with no observable atrophic features
For the cerebral cortex:
- limbic cortex appears within normal limits without apparent atrophy
- no findings suggestive of atrophy are seen in the insular cortex
- no observable atrophic changes in the parietal lobe
- no observable atrophic changes in the frontal lobe
- the occipital lobe shows no notable changes suggestive of atrophy
- temporal lobe appears preserved, with no observable tissue loss
|
AD
|
ADNI_019_S_5242_MR_MPRAGE_br_raw_20130703114825137_136_S193992_I379092
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- the limbic cortex shows no notable changes suggestive of atrophy
- frontal lobe maintains a normal appearance with no observable atrophic features
- no findings suggestive of atrophy are seen in the parietal lobe
- occipital lobe demonstrates a healthy morphology without signs of atrophy
- no clear atrophic alterations are visible in the insular cortex
- no appreciable degenerative or atrophic changes observed in the temporal lobe
For the ventricles:
- the 4th ventricle shows no notable changes suggestive of enlargement
- mild enlargement of the external csf
- no clear enlargement or abnormal growth seen in the inf. lateral ventricle
- no appreciable enlargement noted in the 3rd ventricle
- no evident size increase noted in the lateral ventricle
For the subcortical structures:
- hippocampus appears preserved, with no observable tissue loss
- no observable atrophic changes in the basal forebrain
- no evident atrophy or tissue thinning seen in the caudate
- amygdala demonstrates a healthy morphology without signs of atrophy
- no findings suggestive of atrophy are seen in the ventral dc
- mild atrophy of the left pallidum; normal-to-mild atrophy of the right pallidum
- no observable atrophic changes in the putamen
- no findings suggestive of atrophy are seen in the accumbens
- no clear atrophic alterations are visible in the thalamus
|
CN
|
FTLD_203914152_03251_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10450418_dupl_2
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- mild-to-moderate atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: posterior insula (mild atrophy on the left and mild-to-moderate atrophy on the right), parietal operculum (mild-to-moderate atrophy on the left), frontal operculum (mild atrophy on the left and normal on the right), anterior insula (no significant abnormality) and central operculum (no significant abnormality)
- the occipital lobe shows no notable changes suggestive of atrophy
- mild-to-moderate atrophy of the left temporal lobe; normal-to-mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: middle temporal gyrus (moderate atrophy on the left and mild atrophy on the right), planum temporale (mild-to-moderate atrophy on the left), fusiform gyrus (no significant abnormality), inf. temporal gyrus (no significant abnormality), transverse temporal gyrus (no significant abnormality), sup. temporal gyrus (no significant abnormality), planum polare (no significant abnormality) and temporal pole (no significant abnormality)
- moderate atrophy of the left parietal lobe and mild-to-moderate atrophy of the right parietal lobe; focal volume loss observed in the following subregions: supramarginal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), precuneus (mild atrophy both left/right), sup. parietal lobule (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), angular gyrus (no significant abnormality), postcentral gyrus (no significant abnormality) and postcentral gyrus medial segment (no significant abnormality)
- moderate-to-severe atrophy of the left frontal lobe and mild-to-moderate atrophy of the right frontal lobe; focal volume loss observed in the following subregions: middle frontal gyrus (moderate atrophy both left/right), medial orbital gyrus (mild atrophy both left/right), gyrus rectus (mild atrophy on the left and normal-to-mild atrophy on the right), lateral orbital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), sup. frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), frontal pole (no significant abnormality), medial frontal cortex (no significant abnormality), opercular inf. frontal gyrus (mild atrophy on the left and normal on the right), triangular inf. frontal gyrus (no significant abnormality), posterior orbital gyrus (no significant abnormality), orbital inf. frontal gyrus (no significant abnormality), anterior orbital gyrus (no significant abnormality), precentral gyrus (no significant abnormality), precentral gyrus medial segment (no significant abnormality), subcallosal area (no significant abnormality), sup. frontal gyrus medial segment (no significant abnormality) and supplementary motor cortex (no significant abnormality)
- mild-to-moderate atrophy of the left limbic cortex and mild atrophy of the right limbic cortex; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), posterior cingulate gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), middle cingulate gyrus (no significant abnormality), entorhinal area (no significant abnormality) and parahippocampal gyrus (no significant abnormality)
For the subcortical structures:
- the ventral dc shows no notable changes suggestive of atrophy
- moderate atrophy of the left accumbens and mild-to-moderate atrophy of the right accumbens
- the pallidum shows no notable changes suggestive of atrophy
- mild-to-moderate atrophy of the left caudate and mild atrophy of the right caudate
- no findings suggestive of atrophy are seen in the thalamus
- no clear atrophic alterations are visible in the basal forebrain
- mild atrophy of the left putamen; the right putamen is normal
- moderate atrophy of the left amygdala and mild atrophy of the right amygdala
- the left hippocampus volume is borderline low
For the ventricles:
- moderate enlargement of the left lateral ventricle; normal-to-mild enlargement of the right lateral ventricle
- moderate-to-severe enlargement of the external csf
- mild-to-moderate enlargement of the 3rd ventricle
- mild bilateral enlargement of the inf. lateral ventricle
- 4th ventricle maintains its expected proportions without signs of enlargement
|
BV
|
FTLD_203262794_02496_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177137_dupl_3
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- mild-to-moderate enlargement of the 3rd ventricle
- inf. lateral ventricle maintains a typical volume without observable enlargement
- 4th ventricle appears within normal size limits with no apparent enlargement
- moderate enlargement of the left lateral ventricle and moderate-to-severe enlargement of the right lateral ventricle
- moderate-to-severe enlargement of the external csf
For the cerebral cortex:
- moderate atrophy of the left limbic cortex and moderate-to-severe atrophy of the right limbic cortex; focal volume loss observed in the following subregions: anterior cingulate gyrus (moderate atrophy on the left and moderate-to-severe atrophy on the right), parahippocampal gyrus (mild-to-moderate atrophy both left/right), entorhinal area (mild-to-moderate atrophy on the left and mild atrophy on the right), middle cingulate gyrus (no significant abnormality) and posterior cingulate gyrus (no significant abnormality)
- mild-to-moderate bilateral atrophy of the temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate-to-severe atrophy both left/right), middle temporal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), fusiform gyrus (no significant abnormality), planum polare (no significant abnormality), planum temporale (no significant abnormality), inf. temporal gyrus (no significant abnormality), sup. temporal gyrus (no significant abnormality) and transverse temporal gyrus (no significant abnormality)
- no observable atrophic changes in the occipital lobe
- severe bilateral atrophy of the frontal lobe; focal volume loss observed in the following subregions: medial orbital gyrus (mild-to-moderate atrophy on the left and moderate atrophy on the right), gyrus rectus (mild-to-moderate atrophy both left/right), medial frontal cortex (mild atrophy on the left and moderate atrophy on the right), middle frontal gyrus (moderate atrophy on the left and mild atrophy on the right), sup. frontal gyrus medial segment (moderate atrophy on the left and mild atrophy on the right), frontal pole (mild atrophy on the left and mild-to-moderate atrophy on the right), opercular inf. frontal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), anterior orbital gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), triangular inf. frontal gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), posterior orbital gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), precentral gyrus medial segment (no significant abnormality), sup. frontal gyrus (mild atrophy both left/right), supplementary motor cortex (mild atrophy both left/right), lateral orbital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), orbital inf. frontal gyrus (mild atrophy on the left), subcallosal area (no significant abnormality) and precentral gyrus (no significant abnormality)
- moderate-to-severe bilateral atrophy of the insular cortex; focal volume loss observed in the following subregions: anterior insula (severe atrophy both left/right), frontal operculum (mild-to-moderate atrophy both left/right), posterior insula (mild atrophy on the left and mild-to-moderate atrophy on the right), parietal operculum (no significant abnormality) and central operculum (no significant abnormality)
- parietal lobe maintains a normal appearance with no observable atrophic features
For the subcortical structures:
- mild atrophy of the left hippocampus
- mild-to-moderate atrophy of the right hippocampus
- severe bilateral atrophy of the amygdala
- ventral dc demonstrates a healthy morphology without signs of atrophy
- severe bilateral atrophy of the putamen
- moderate-to-severe atrophy of the left pallidum and moderate atrophy of the right pallidum
- no evident atrophy or tissue thinning seen in the thalamus
- severe bilateral atrophy of the caudate
- no findings suggestive of atrophy are seen in the basal forebrain
- severe bilateral atrophy of the accumbens
|
BV
|
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