['multiple myeloma']
['daratumumab', 'lenalidomide', 'dexamethasone']

        Inclusion Criteria:

          -  Must have documented multiple myeloma and measurable disease

          -  Must have received at least 1 prior line of therapy for multiple myeloma and achieved
             a response (partial response or better) to at least one prior regimen

          -  Must have documented evidence of progressive disease as defined by the International
             Myeloma Working Group criteria on or after their last regimen

          -  Must have an Eastern Cooperative Oncology Group Performance Status score of 0, 1, or 2

          -  If a participant has received subsequent anticancer therapy (salvage therapy), the
             participant must have a "wash-out period" defined as 2 weeks or 5 pharmacokinetic
             half-lives of the treatment, whichever is longer, before the planned start date of
             daratumumab monotherapy. The only exception is the emergency use of a short course of
             corticosteroids (equivalent of dexamethasone 40 milligram per day for a maximum of 4
             days) before Daratumumab monotherapy

        Exclusion Criteria:

          -  Has received any of the following therapies: daratumumab or other anti-CD38 therapies

          -  Has received anti-myeloma treatment within 2 weeks or 5 pharmacokinetic half-lives of
             the treatment

          -  Disease shows evidence of refractoriness or intolerance to lenalidomide or if
             previously treated with a lenalidomide-containing regimen the participant is excluded
             if he or she discontinued due to any adverse event related to prior lenalidomide
             treatment

          -  Has received autologous stem cell transplantation within 12 weeks before the date of
             randomization, or previously received an allogenic stem cell transplant (regardless of
             timing), or planning to undergo a stem cell transplant prior to progression of disease

          -  History of malignancy (other than multiple myeloma) within 5 years before the first
             dose of daratumumab monotherapy (exceptions are squamous and basal cell carcinomas of
             the skin and carcinoma in situ of the cervix, or breast, or other non-invasive lesion,
             that in the opinion of the investigator, with concurrence with the sponsor's medical
             monitor, is considered cured with minimal risk of recurrence within 5 years)
      