['ovarian cancer']
['lurbinectedin (pm01183)', 'pegylated liposomal doxorubicin (pld)', 'topotecan']

        Inclusion Criteria:

          -  Age >/= 18 years

          -  Confirmed diagnosis of unresectable epithelial ovarian, fallopian tube or primary
             peritoneal cancer.

          -  Platinum-resistant disease (PFI: 1-6 months after last platinum-containing
             chemotherapy).

          -  Evaluable disease according to Response Evaluation Criteria in Solid Tumors (RECIST)
             v.1.1 criteria

          -  No more than three prior systemic chemotherapy regimens

          -  Eastern Cooperative Oncology Group (ECOG) performance status (PS) (ECOG PS) ≤ 2

          -  Adequate hematological, renal, metabolic and hepatic function

        Exclusion Criteria:

          -  Concomitant diseases/conditions: cardiac disease, immunodeficiency, chronic active
             hepatitis or cirrhosis, uncontrolled infection, bowel obstruction, any other major
             illness

          -  Prior treatment with PM01183, trabectedin, or with both PLD and topotecan.

          -  Requirement of permanent or frequent (i.e., once per week) external drainages within
             two weeks prior to randomization
      