['multiple sclerosis, relapsing-remitting']
['dimethyl fumarate']

        Key Inclusion Criteria:

          -  Must have a confirmed diagnosis of RRMS according to McDonald criteria (Polman,
             Reingold et al. 2005).

          -  Must have a baseline EDSS between 0.0 and 5.0, inclusive.

          -  Must have experienced at least 1 relapse within the 12 months prior to randomization,
             with a prior brain MRI demonstrating lesion(s) consistent with MS, or show evidence of
             gadolinium-enhancing lesion(s) of the brain on an MRI performed within the 6 weeks
             prior to randomization.

        Key Exclusion Criteria:

        Candidates will be excluded from study entry if any of the following exclusion criteria
        exist at the time of screening:

          -  Primary progressive, secondary progressive, or progressive relapsing MS, as defined by
             Lublin and Reingold (Lublin and Reingold 1996)

          -  Severe depression (MADRS score >34) (Montgomery and Asberg 1979)

          -  History of malignancy (except basal cell carcinoma that has been completely excised
             prior to study enrollment)

          -  An MS relapse that has occurred within the 30 days prior to inclusion AND/OR the
             participant has not stabilized from a previous relapse prior to inclusion.
      