['schizophrenia']
['brexpiprazole', 'aripiprazole']

        Inclusion Criteria:

          -  18 to 65 years of age, inclusive, at the time of informed consent with a diagnosis of
             schizophrenia as defined by the Diagnostic and Statistical Manual of Mental Disorders,
             Fourth Edition, Text Revision (DSM-IV-TR) and confirmed by the Mini International
             Neuropsychiatric Interview (M.I.N.I) for Schizophrenia and Psychotic Disorders Studies

          -  Would benefit from hospitalization or continued hospitalization for treatment of a
             current acute relapse of schizophrenia at trial entry

          -  Are experiencing an acute exacerbation of psychotic symptoms and marked deterioration
             of usual function as demonstrated by all of the following:

          -  Positive and Negative Syndrome Scale (PANSS) Total Score of ≥ 80

          -  Score of ≥ 4 on two or more of the following PANSS items at screening: hallucinatory
             behavior, unusual thought content, conceptual disorganization, or suspiciousness

          -  Clinical Global Impression - Severity of Illness Scale (CGI-S) score ≥ 4 (moderately
             ill)

        Exclusion Criteria:

          -  Are presenting with a first episode of schizophrenia based on the clinical judgment of
             the investigator

          -  Have been hospitalized > 21 days for the current acute episode at the time of the
             baseline visit

          -  Have a current DSM-IV-TR Axis I diagnosis other than schizophrenia, including, but not
             limited to, schizoaffective disorder, major depressive disorder (MDD), bipolar
             disorder, post-traumatic stress disorder, anxiety disorders, delirium, dementia,
             amnestic, or other cognitive disorders; also borderline, paranoid, histrionic,
             schizotypal, schizoid, antisocial personality disorders or mental retardation.

          -  Improvement of ≥ 20% in total PANSS score between the screening and baseline
             assessments.
      