
    no patient included at target sample sizes
  
['pneumonia, ventilator-associated', 'colistin adverse reaction', 'infection due to multidrug resistant acinetobacter', 'infection resistant to multiple drugs']
['aerosolized plus intravenous colistin', 'intravenous colistin']

        Inclusion Criteria:

          -  Neonates who are admitted to the neonatal intensive care unit, Hat Yai Hospital during
             the study period.

          -  Neonates who were complicated with VAP due to PDR-Acinetobacter baumannii susceptible
             to colistin (by minimal inhibitory concentration (MIC) < 2 mcg/dL).

        Exclusion Criteria:

          -  Neonates who have a major anomaly or chromosomal abnormality.

          -  Neonates who receive colistin prior 7 days prior to study.

          -  Neonates who have a significant renal dysfunction defined as a serum creatinine (SCr)
             >1.5 mg/dL or a decrease in urine output to < 1 mL/kg/h;
      