['diabetic foot ulcers']
['chitosan', 'isosorbide dinitrate', 'placebo']

        Inclusion Criteria:

          -  Patients with diabetic foot ulcers in grade I and II of the classification of Wagner

          -  with leg arm index> 0.8 and

          -  without specific treatment for foot ulcers referred to the experimental and clinical

        Exclusion Criteria:

          -  Patients with another type of topical medication

          -  patients with diabetic foot ulcers in grade III and

          -  with leg arm index <0.8
      