['essential tremor']
['sage-547', 'placebo']

        Inclusion Criteria:

          -  Males and females, 35-75 years old with a diagnosis of essential tremor with symptoms
             clearly present in at least 1 upper limb; patient has had tremor present for at least
             2 years prior to Screening

          -  Off medication, or on a stable dose of medication for their tremor for at least 28
             days prior to Screening

        Exclusion Criteria:

          -  Recent history or active clinically significant manifestations of metabolic, hepatic,
             renal, hematological, pulmonary, cardiovascular, gastrointestinal, musculoskeletal,
             dermatological, urogenital, eyes, ears, nose, or throat, psychiatric, or neurological
             (other than essential tremor) disorders

          -  Medical history of seizures
      