
    low recruitment rate
  
['intermittent claudication']
['omega-3 fatty acids']

        Inclusion Criteria:

          -  Age ≥ 18

          -  Newly diagnosed intermittent claudication

          -  Ankle Brachial Index < 0.8 at rest or > 0.15 decrease after exercise

          -  Able to perform standardised treadmill walking test for 2 min

          -  Written informed consent

        Exclusion Criteria:

          -  Unable to fill out a questionnaire (cognitive impairment or insufficient knowledge of
             the Dutch language)

          -  Heart failure or unstable cardiac status (angina pectoris class III or IV or recent
             myocardial infarction < 3 months)

          -  Any illness with rapid evolution or a life expectancy < 3 months

          -  Recent cerebrovascular accident (< 3 months)

          -  Current use of fish oil supplements or > 2 times a week dietary fish

          -  Pregnancy

          -  Fish, soybean or peanut allergy

          -  Contra indications for the use of omega-3 fatty acids

          -  Use of oral anticoagulants (coumarin derivatives)
      