['asthma']
['benralizumab', 'benralizumab placebo', 'seasonal influenza virus vaccine']

        Inclusion Criteria:

          -  Female and male patients aged 12 to 21 years, inclusive, at the time of Visit 1

          -  Weight of ≥40 kg

          -  Documented history of current treatment with Inhaled corticosteroids (ICS) and
             long-acting β2 agonists (LABA)

          -  Morning pre-bronchodilator forced expiratory volume in 1 second (FEV1) of >50%
             predicted at Visit 1 or Visit 2.

          -  Airway reversibility (FEV1 >12% and 200 ml) demonstrated at Visit 1 or Visit 2 using
             the Maximum Post-bronchodilator Procedure OR

          -  Airway reversibility documented in the previous 12 months prior to Visit 1

          -  An exacerbation, 1 or more, that required oral corticosteroids in the previous year OR

          -  Any condition assessed by patient recall over the previous 2-4 weeks

        Exclusion Criteria:

          -  Clinically important pulmonary disease other than asthma

          -  Known history of allergy or reaction to the Investigational Product formulation or
             influenza vaccine

          -  Receipt of an influenza vaccine within 90 days prior to randomization

          -  Poorly controlled asthma during the screening period that requires treatment with oral
             corticosteroids or a hospitalization/emergency room visit for the treatment of asthma

          -  Acute illness or evidence of significant active infection or known influenza infection
             during the current flu season
      