['rheumatoid arthritis']
['sarilumab', 'sulfasalazine', 'leflunomide', 'bucillamine', 'tacrolimus', 'mizoribine']

        Inclusion criteria:

        Diagnosis of rheumatoid arthritis (RA), according to the American College of
        Rheumatology/The European League Against Rheumatism (ACR/EULAR) 2010 Rheumatoid Arthritis
        Classification Criteria with >=3 months disease duration.

        Moderately to severely active RA defined as:

          -  At least 4 of 68 tender joints and 4 of 66 swollen joints at screening visit.

          -  High sensitivity C-Reactive Protein (hs-CRP) >=4 mg/L or Erythrocyte Sedimentation
             Rate (ESR) >=28 mm/hr at screening visit.

        For the combination stratum:

        Participants who had continuous treatment with non-biologic DMARDs other than MTX for at
        least 12 weeks prior to the randomization and on a stable dose for a minimum of 6 weeks
        prior to screening.

        For the monotherapy stratum:

        Participants who per investigator judgment were any of inappropriate, intolerant or
        inadequate to MTX treatment.

        Exclusion criteria:

        Participants <20 years of age. Prior treatment with tumor necrosis factor (TNF) antagonists
        or any other RA-directed biologic agents without the appropriate off-drug period prior to
        screening.

        Prior treatment with anti-interleukin-6 (anti-IL-6) or anti-interleukin-6 receptor (IL-6R)
        antagonist therapies, including but not limited to tocilizumab or sarilumab.

        The above information was not intended to contain all considerations relevant to a
        participant's potential participation in a clinical trial.
      