['schizophrenia']
['low dose asenapine maleate transdermal patch', 'high dose asenapine maleate transdermal patch', 'placebo']

        Inclusion Criteria:

          -  Current diagnosis of schizophrenia.

          -  Subject has PANSS total score ≥80, AND score of 4 or more in at least 2 of the
             following PANSS items at Screening and at Baseline: conceptual disorganization
             delusions; hallucinatory behavior; unusual thought content.

          -  Subjects must be able to wear a transdermal patch for 24 hours.

        Exclusion Criteria:

          -  Subject has been diagnosed with schizophrenia less than 6 months prior to Screening
             Visit.

          -  Subject has received within 90 days of Screening Visit: electroconvulsive therapy;
             transcranial magnetic stimulation; vagal nerve stimulation; or other brain stimulation
             treatments

          -  Subject has experienced acute depressive symptoms within 30 days prior to Screening
             Visit that requires treatment with an antidepressant, as determined by the
             Investigator.

          -  Currently taking clozapine for the treatment of schizophrenia.

          -  Has hypothyroidism or hyperthyroidism.

          -  Subject is currently being treated with insulin for diabetes.

          -  Subject has epilepsy or history of seizures.

          -  Positive urine pregnancy test.
      