['osteoarthritis, knee']
['miv-711', 'placebo']

        Inclusion Criteria:

          -  Current average knee pain, defined as pain in either knee, within 1 week before visit
             1, for which the patient gives a severity score of ≥4, <10 on a 0-10 NRS (Numeric
             Rating Scale).

          -  Inclusive of 40-80 years old.

          -  Diagnosis of primary knee osteoarthritis

        Exclusion Criteria:

          -  The presence of any inflammatory arthritis

          -  Any generalized pain condition that may interfere with the evaluation of the target
             knee pain (e.g., fibromyalgia) as judged by the investigator.

          -  Any clinically severe or significant uncontrolled concurrent illness, which, in the
             opinion of the Investigator, would impair ability to give informed consent or take
             part in or complete this clinical study.

          -  Known or suspected intolerance or hypersensitivity to the investigational product,
             closely related compounds, or any of the stated ingredients.
      