['hypercholesterolemia']
['ezetimibe', 'placebo to evolocumab', 'placebo ezetimibe']

        Inclusion Criteria:

          -  Male or female ≥ 20 to ≤ 80 years of age

          -  Japanese by self-identification

          -  Not on a statin or on a low dose statin with stable dose for at least 4 weeks.

          -  Subject not at LDL-C goal

          -  History of statin intolerance to at least 2 statins

          -  Lipid lowering therapy has been stable prior to screening for at least 4 weeks

          -  Fasting triglycerides ≤ 400 mg/dL

        Exclusion Criteria:

          -  New York Heart Association (NYHA) III or IV heart failure

          -  Uncontrolled cardiac arrhythmia

          -  Uncontrolled hypertension

          -  Type 1 diabetes

          -  Poorly controlled type 2 diabetes

          -  Uncontrolled hypothyroidism or hyperthyroidism
      