['post-menopausal vasomotor symptoms']
['bay3427080', 'placebo (for bay3427080)']

        Inclusion Criteria:

          -  Post-menopausal female subjects experiencing frequent moderate to severe hot
             flashes.Menopause will be defined as:

               -  12 months of spontaneous amenorrhea;

               -  OR at least 6 weeks' post-surgical bilateral oophorectomy with or without
                  hysterectomy.

        Exclusion Criteria:

          -  BMI > 35kg/m2.

          -  Any active comorbid disease, ECG or laboratory result deemed by the investigator to be
             clinically significant and which could impact safety during study conduct or that
             could interfere with the study evaluation, procedures or completion.

          -  Use of prohibited medications defined in the protocol.

          -  Inability or unwillingness to comply with study procedures or requirements.
      