
    the number of enrolled subjects did not meet the goal during the study
  
['allergic rhinitis']
['hollisterstier', 'normal saline']

        Inclusion Criteria:

          -  Allergic rhinitis to house dust mite (Df, Dp), cat or dog

          -  More than 3mm reaction at skin prick test for Df, Dp, cat or dog or more than class 3
             at serum specific IgE level (UNICAP or MAST)

        Exclusion Criteria:

          -  Uncontrolled or severe asthma according to Global Initiative of Asthma (GINA)
             guideline

          -  FEV1 less than 50% of predicted value if there is comorbid asthma.

          -  Subject rejects the enrollment into study

          -  Low compliance

          -  Pregnancy or lactation

          -  Significant cardiovascular, hepatic, renal, hematologic, oncologic, or infectious
             diseases

          -  Administration of beta blocker, angiotensin converting enzyme inhibitor, tricyclic
             antidepressant, immnosuppressant including systemic glucocorticosteroid (20mg or more
             dose of prednisolone or equivalent dose of other steroid) within last 2 weeks

          -  Prior history of allergen-specific immunotherapy

          -  Allergic rhinitis caused by other perennial or seasonal allergen

          -  Vulnerable volunteer
      