['osteoarthritis', 'pain syndrome', 'intra-articular injection']
['hyaluronic acid', 'hyaluronic acid and corticosteroids']

        Inclusion Criteria:

        According to radiographic findings, patients who are suffering from knee OA for over 3
        months have to be stage II-IV according to the Kellgren-Lawrence (KL) grade by a senior
        radiologist. The diagnosis of symptomatic knee OA is based on American Rheumatism
        Association classification criteria for knee osteoarthritis.

        Exclusion Criteria:

        Exclusion criteria are the diagnosis of rheumatoid arthritis or other inflammatory OA,
        presence of trauma or pain-causing diseases, treatment with oral medications in recent 3
        days, physiotherapy and intra-articular injection of HA or CS in the past 6 months.
        Participants who are allergic to any of the medications used in this study or diagnosed
        with current systemic infection are also excluded.
      