['complex regional pain syndrome', 'reflex sympathetic dystrophy']
['axs-02 (oral zoledronate)', 'placebo']

        Key Inclusion Criteria:

          -  Male or female of at least 18 years of age

          -  Recently confirmed diagnosis of CRPS-1 (Budapest criteria)

          -  Average pain intensity score of ≥ 5 (based on an 11-point scale [0 - 10])

          -  Willing and able to provide written informed consent

        Key Exclusion Criteria:

          -  Received chronic opioid therapy within 4 weeks

          -  Received a sympathetic nerve block within 3 weeks

          -  Active litigation or a pending workers' compensation decision

          -  Any other clinically significant medical or pain condition (eg, Parkinson's disease,
             cognitive impairment, or fibromyalgia) or clinical laboratory abnormality that would
             in the investigator's judgment interfere with the subject's ability to participate in
             the study
      