['interstitial cystitis', 'bladder pain syndrome', 'painful bladder syndrome', 'chronic interstitial cystitis']
['aqx-1125 100 mg', 'aqx-1125 200 mg', 'placebo']

        Inclusion Criteria:

          -  Be male or female, ≥18 and ≤80 years of age who have had symptoms of bladder pain in
             addition to urinary urgency and/or urinary frequency for more than 6 months

          -  Have had a clinical diagnosis, or history consistent with the diagnosis, of
             interstitial cystitis/bladder pain syndrome for >3 months but ≤20 years

          -  Must be capable of voiding independently

          -  Have undergone a cystoscopy within the last 36 months prior to Baseline

          -  Women of child bearing potential must have a negative pregnancy test, be non-lactating
             and agree to avoid pregnancy and use a highly effective method of contraception with
             one additional barrier method of contraception from screening until at least 28 days
             after the last dose of study drug has been taken

          -  Men must use a condom for sexual intercourse from screening until at least 90 days
             after last dose of study drug has been taken, unless they have been surgically
             sterilized (vasectomy)

        Exclusion Criteria

          -  Have had a urinary tract infection (UTI) including bacterial cystitis within the past
             30 days

          -  Microscopic hematuria that has not been adequately evaluated as per local standard of
             care

          -  Have a history of chronic substance abuse, dependency or abuse of opiates, or other
             narcotics within the last 2 years

          -  History of previous procedure(s) (augmentation cystoplasty, cystectomy, cytolysis,
             botulinum toxin or bladder catheterization) that has significantly affected bladder
             function

          -  History of cyclophosphamide or chemical cystitis, urinary tuberculosis or radiation
             cystitis

          -  Women: History of bladder tumors; uterine, cervical, vaginal or urethral cancer

          -  Men: History of prostate surgery (transurethral resection of the prostate [TURP],
             transurethral resection tumor [TURT], transurethral incision of the prostate [TUIP],
             transurethral needle ablation [TUNA] etc.), a history of prostate cancer or currently
             being treated for chronic bacterial prostatitis

          -  Major surgery within 3 months prior to Screening
      