['smoking cessation']
['simvastatin', 'placebo']

        Inclusion Criteria:

          -  Age >=18 and <=70 years,

          -  Smoking more than 10 cigarettes per day for at least 1 year,

          -  Motivated to quit smoking,

          -  Without legal tutors or subordination,

          -  Affiliated to a health insurance system as required by the French law on biomedical
             research,

          -  Written informed consent for participation in the study.

        Exclusion Criteria:

          -  Age < 18 or > 70 years,

          -  Presenting a contraindication to simvastatin use,

          -  With depression and/or psychosis and/or cognitive disorder and/or mental retardation
             or chronic use of medications for these disorders,

          -  Substance use disorder other than smoking,

          -  More than 3 months of abstinence from cigarette smoking in the previous year,

          -  Use of nicotine replacement therapy, bupropion, varenicline on last 3 months,

          -  Use of clonidine or nortriptyline on last 3 months,

          -  Undergoing on last 3 months' cognitive-behavioral therapy for smoking cessation,

          -  Premenopausal women without contraception.
      