['cystic fibrosis']
['qr-010', 'placebo']

        Inclusion Criteria:

          -  Confirmed diagnosis of CF as defined by iontophoretic pilocarpine sweat chloride test
             (sweat chloride) of > 60 mmol/L

          -  Confirmation of CFTR gene mutations homozygous for the ΔF508 mutation

          -  Body mass index (BMI) ≥ 17 kg/m2

          -  Non-smoking for a minimum of two years

          -  FEV1 ≥70% of predicted normal for age, gender, and height, at Screening

          -  Stable lung function

          -  Adequate hepatic and renal function

        Exclusion Criteria:

          -  Breast-feeding or pregnant

          -  Use of lumacaftor or ivacaftor

          -  Use of any investigational drug or device

          -  History of lung transplantation

          -  Hemoptysis
      