['type 2 diabetes mellitus']
['metformin', 'hms5552']

        Inclusion Criteria:

          -  Male and/or female subjects between the ages of 18 and 70 years

          -  Body Mass Index (BMI) of approximately 22 to 38kg/m2

          -  HbA1c ≥7% and ≤12%

          -  Are capable of giving informed consent and complying with study procedures

        Exclusion Criteria:

          -  fasting blood glucose ≤110 or ≥270mg/dL

          -  Type 1 diabetes mellitus, or latent autoimmune diabetes in adults

          -  History or symptoms of clinically significant cardiovascular disease, particularly
             coronary artery disease, arrhythmias, atrial tachycardia, or congestive heart disease
             within one year of screening

          -  History of liver disease and clinically significant renal disease

          -  Known hypersensitivity to metformin hydrochloride;

          -  Positive pregnancy test result;
      