['depression']
['omega-3 supplement', 'placebo']

        Inclusion Criteria:

          -  Documented coronary heart disease

          -  Diagnosis of major depression based on structured interview

        Exclusion Criteria:

          -  Moderate to severe cognitive impairment

          -  Meets DSM-5 criteria for depressive disorder due to a general medical condition or
             medication

          -  Major Axis I psychiatric disorder other than unipolar depression or an anxiety
             disorder, a high risk of suicide, or current substance abuse other than tobacco;

          -  Not expected to survive one year or physically unable to tolerate the study protocol

          -  Known sensitivity to sertraline or omega-3, or an allergy to fish oil or shellfish

          -  Taking an antidepressant or an omega-3 supplement at baseline

          -  Exempted by their cardiologist or primary care physician

          -  Refuses to provide informed consent

          -  Participating in a competing protocol or trial
      