
    poor accrual due to change in standard of care procedure.
  
['postoperative pain', 'postoperative nausea and vomiting', 'quality of life']
['ropivacaine', 'saline']

        Inclusion Criteria:

          -  Be Female aged 18-100 years.

          -  Choose mastectomy followed by bilateral immediate tissue expander breast
             reconstruction.

          -  Have no inflammatory breast cancers.

          -  Be aware of the nature of her malignancy.

          -  Understand the study purpose, requirements, and risks.

          -  Be able and willing to give informed consent.

        Exclusion Criteria:

          -  Any concurrent opioid analgesic use (baseline opioid use must be 0 to be eligible).

          -  Liver dysfunction and/ or cirrhosis.

          -  Renal insufficiency, with creatinine greater than 1.5 mg/mL.

          -  Patients weighing less than 50 Kg.

          -  Concurrent use of the SSRI antidepressant fluvoxamine (Luvox).
      