
    major technical hindrance in recruitment.
  
['acute ischemic stroke']
['placebo', 'dlbs1033']

        Inclusion Criteria:

          -  Male or female subjects with age of 18-75 years .

          -  Has been diagnosed with acute ischemic stroke clinically confirmed by CT scan.

          -  Modified National Institutes of Health Stroke Scale (mNIHSS) score >= 5.

          -  Patients present at hospital and receiving first dose of study medication within 72
             hours after the onset of the stroke symptoms.

          -  Able to take oral medication.

        Exclusion Criteria:

          -  For females of childbearing potential: pregnancy and lactation period.

          -  History of or current hemorrhagic stroke (within the last 3 months).

          -  Transient ischemic stroke (TIA).

          -  Patients with seizure at the onset of stroke.

          -  History of serious head injury within the last 3 months.

          -  History of major surgery within the last 3 months.

          -  Serious cardiovascular conditions, such as myocardial infarction, CHF grade III and IV
             (NYHA classification), aorta dissection, and atrial fibrillation within the last 6
             months.

          -  Presence of severe renal or hepatic dysfunction

          -  Presence of acute or chronic infections.

          -  Thrombocytopenia (thrombocytes level < 150.000/ul).

          -  Patients with higher risks of bleeding.

          -  Uncontrolled hypertension (systolic blood pressure > 185 mmHg or diastolic blood
             pressure > 110 mmHg).

          -  Random plasma glucose >= 200 mg/dL.

          -  Current or regular use of oral anticoagulants, antiplatelets other than study
             medication, and herbal medicines.

          -  Hypersensitive to the investigational product(s).
      