['gastric cancer']
['ono-4538', 'placebo']

        Inclusion Criteria:

          -  Men & women ≥20 years of age

          -  Unresectable advanced or recurrent gastric cancer (including esophagogastric junction
             cancer)

          -  Histologically confirmed adenocarcinoma

          -  Refractory to or intolerant of standard therapy

          -  ECOG Performance Status score 0 or 1

          -  A life expectancy of at least 3 months

        Exclusion Criteria:

          -  Current or past history of severe hypersensitivity to any other antibody products

          -  Patients with multiple primary cancers

          -  Patients with any metastasis in the brain or meninx that is symptomatic or requires
             treatment

          -  Patients with active, known or suspected autoimmune disease
      