['spondylitis, ankylosing']
['secukinumab', 'placebo secukinumab']

        Inclusion criteria: moderate to severe AS, prior radiographic evidence according to the
        Modified NY Criteria (1984), inadequate response to NSAIDs. -- Exclusion criteria:
        pregnancy or lactation, on-going infectious or malignant process on a chest X-ray or MRI,
        previous exposure to IL-17 or IL-17R targeting therapies, previous exposure to any
        biological immunomodulating agent excluding TNF antagonists, previous cell depleting
        therapy.
      