['hcv', 'hepatitis c infection', 'genotype 4']
['2 daa', 'rbv']

        Inclusion Criteria:

          -  Chronic hepatitis C, genotype 4-infection (hepatitis C virus [HCV] ribonucleic acid
             [RNA] level greater than 1,000 IU/mL at Screening)

          -  Subjects must meet one of the following:

               -  Treatment-naive: Subject has never received antiviral treatment for HCV infection
                  OR

               -  Treatment Experienced (Prior null responders, Partial responders or Relapsers to
                  pegylated-interferon [pegIFN]/RBV);

          -  Females must be post-menopausal, of non-child bearing potential or practicing specific
             forms of birth control

          -  In substudy 1, demonstrated absence of liver cirrhosis as confirmed by liver biopsy or
             Fibroscan

          -  In substudy 2, evidence of liver cirrhosis as confirmed by liver biopsy or Fibroscan
             with Child-Pugh score less than or equal to 6 at Screening and confirmed absence of
             hepatocellular carcinoma

        Exclusion Criteria:

          -  Females who are pregnant or breastfeeding

          -  Positive screen for hepatitis B Surface antigen or anti-Human Immunodeficiency virus
             antibody

          -  HCV genotype performed during screening indicating unable to genotype or co-infection
             with any other HCV genotype

          -  abnormal laboratory tests

          -  self-reports current drinking more than 2 drinks per day

          -  current enrollment in another investigational study

          -  previous treatment with a direct acting antiviral agent (DAA) containing regimen

          -  In substudy 1, evidence of liver cirrhosis

          -  In substudy 2, evidence of current or past Child-Pugh B or C classification and
             confirmed presence of hepatocellular carcinoma
      