['hypercholesterolemia']
['cat-2054', 'placebo', 'atorvastatin']

        Inclusion Criteria:

          -  Between 18 and 74 years at Screening

          -  Hypercholesterolemia (LDL-C ≥ 70 mg/dL and < 190 mg/dL) plus a stable dose of statin
             for at least 4 weeks prior to Screening

          -  Satisfies one of the following:

               1. Female patients of childbearing potential must have used appropriate and highly
                  effective contraception (a regimen which results in a failure rate of <1% per
                  year) with their partners for 4 weeks prior to Screening, and remain compliant
                  during the treatment phase and until 4 weeks after the last dose of
                  investigational product

               2. Male patients must use an acceptable and highly effective contraceptive method
                  during the treatment phase and until 4 weeks after the last dose of
                  investigational product

          -  Body mass index (BMI) ≤45 kg/m2

        Exclusion Criteria:

          -  History of any major cardiovascular event (stroke, TIA, MI, PTCI, CABG,
             hospitalization due to heart failure) within 6 months of Screening

          -  Type I diabetes mellitus or use of insulin

          -  Active peptic ulcer disease or a history of muscle disease or myopathy
      