['gout']
['rdea3170']

        Inclusion Criteria:

          -  Subject has a body weight ≥ 50 kg (110 lbs.) and a body mass index ≥ 18 and ≤ 40
             kg/m2.

          -  Subject with renal impairment, as determined at Screening, with creatinine clearance
             as calculated by the Cockcroft-Gault formula of 60 to < 90 mL/min (mild impairment),
             30 to < 60 mL/min (moderate impairment), or 15 to < 30 mL/min (severe impairment), or
             a matched control subject (by age and body mass index) with a creatinine clearance of
             ≥ 90 mL/min.

          -  Subject has a Screening serum urate level ≥ 4.5 mg/dL and ≤ 10 mg/dL

        Exclusion Criteria:

          -  Subject has a history or clinical manifestations of significant metabolic,
             hematological, pulmonary, cardiovascular, gastrointestinal, neurologic, hepatic,
             renal, urological, or psychiatric disorders.

          -  Subject has a history or suspicion of kidney stones.

          -  Subject has a history of asthma.

          -  Subject has undergone major surgery within 3 months prior to Day 1.

          -  Subject has donated blood or experienced significant blood loss (> 450 mL) within 12
             weeks prior to Day 1 or gave a plasma donation
      