["alzheimer's disease"]
['iti-007', 'placebo', 'iti-007', 'placebo']

        Inclusion Criteria:

        Part 1

          -  Healthy geriatric volunteers

          -  MMSE score of >= 26 at screening

          -  BMI between 19.0 and 40.0 kg/m2 and a minimum body weight of 50 kg at screening

        Part 2

          -  Geriatric patients with a clinical diagnosis of dementia

          -  MMSE score of < 26 at screening

          -  BMI between 19.0 and 40.0 kg/m2 and a minimum body weight of 50 kg at screening

        Exclusion Criteria:

          -  Any clinically significant illness within 6 months before screening

          -  Any history of cancer within last 5 years

          -  History of Hepatitis B or C infection and elevated ALT, AST or bilirubin above the
             upper limit of normal level

          -  Any subject considered to be an imminent danger to themselves or others
      