['dry eye']
['omega-3 supplements', 'placebo']

        Inclusion Criteria:

          -  Greater than or equal to 2 of the following 4 signs in the same eye at screening and
             baseline visits (Same signs must be present at Screening and Baseline visits):
             Conjunctival staining present greater than or equal to 1 (out of possible score of 6
             per eye), Corneal fluorescein staining present greater than or equal to 4 (out of a
             possible score of 15 per eye), Tear film break up time (TBUT) less than or equal to 7
             seconds, Schirmer's test greater than or equal to 1 to less than or equal to 7 mm in 5
             minutes.

          -  Ocular Surface Disease Index (OSDI) score: 25-80 at screening, 21-80 at baseline.

          -  Symptoms of DED for greater than or equal to 6 months.

          -  Use of or desire to use artificial tears at least 2 times per day in preceding 2
             weeks.

          -  Ability to swallow large, soft gelcaps

        Exclusion Criteria:

          -  Allergic to ingredients in supplements or placebo

          -  Contact lens wear

          -  Pregnant, nursing, or lactating

          -  Current ocular infection, inflammation, or acute allergic conjunctivitis

          -  History of: ocular herpetic keratitis, ocular surgery in past 6 months, LASIK surgery,
             use of glaucoma medicine or surgery for glaucoma, liver disease, atrial fibrillation,
             hemophilia or bleeding tendencies

          -  Currently on anticoagulation therapy

          -  Eyelid abnormalities or extensive ocular scarring

          -  Use of EPA/DHA supplements in excess of 1200 mg per dayi

          -  Current use, insufficient washout period, or intent to change specific treatments for
             dry eye disease
      