['essential tremor']
['sage-217', 'sage-217', 'placebo']

        Key Inclusion Criteria:

          -  Participant must have a diagnosis of Essential Tremor (ET), defined as bilateral
             postural tremor and kinetic tremor, involving hands and forearms, that is visible and
             persistent and the duration is >5 years prior to screening.

        Key Exclusion Criteria:

          -  Participant has presence of abnormal neurological signs other than tremor or Froment's
             sign.

          -  Participant has presence of known causes of enhanced physiological tremor.

          -  Participant has concurrent or recent exposure (14 days prior to admission visit) to
             tremorogenic drugs.

          -  Participant has had direct or indirect trauma to the nervous system within 3 months
             before the onset of tremor.

          -  Participant has historical or clinical evidence of tremor with psychogenic origin.

          -  Participant has convincing evidence of sudden tremor onset or evidence of stepwise
             deterioration of tremor.
      