['idiopathic parkinson disease']
['pf-06649751', 'trimethobenzamide hydrochloride', 'placebo']

        Inclusion Criteria:

          -  L-DOPA-responsiveness

          -  Hoehn & Yahr Stage II-III inclusive

          -  Experiencing motor fluctuations

          -  Stable daily dose of L-DOPA of at least 300 mg

          -  Females on non-childbearing potential and male subjects

        Exclusion Criteria:

          -  History of troublesome dyskinesias

          -  History of surgical intervention for Parkinson's disease
      