
    the study was closed due to low patient enrollment and the sponsor's decision to include
    patients with squamous nsclc into the go29431 study, nct02409342.
  
['non-small cell lung cancer']
['atezolizumab', 'carboplatin', 'cisplatin', 'gemcitabine']

        Inclusion Criteria:

          -  Histologically or cytologically confirmed Stage IV squamous NSCLC

          -  Tumor programmed death-ligand 1 (PD-L1) expression, as determined by
             immunohistochemistry (IHC) assay of archival tumor tissue or tissue obtained at
             screening

          -  No prior treatment for Stage IV squamous NSCLC

          -  Measurable disease as defined by RECIST v1.1

          -  Eastern Cooperative Oncology Group (ECOG) performance status 0 or 1

          -  Adequate hematologic and end-organ function

        Exclusion Criteria:

          -  Active or untreated central nervous system (CNS) metastases

          -  Untreated or inadequately treated spinal cord compression

          -  Leptomeningeal disease

          -  Uncontrolled pleural effusion, pericardial effusion, or ascites

          -  Uncontrolled tumor-related pain

          -  Uncontrolled hypercalcemia

          -  Any other malignancies within 5 years except those with negligible risk of metastasis
             or death

          -  Pregnant or lactating women

          -  Known hypersensitivity to any component of atezolizumab formulation or other study
             medication

          -  History of autoimmune disease except controlled, treated hypothyroidism or type I
             diabetes

          -  Prior allogeneic bone marrow or solid organ transplantation

          -  Positive human immunodeficiency virus (HIV) test

          -  Active hepatitis B or C

          -  Active tuberculosis

          -  Significant cardiovascular disease

          -  Severe infection or major surgery within 4 weeks prior to randomization

          -  Use of any approved anti-cancer therapy within 3 weeks prior to treatment

          -  Use of an investigational agent or participation in another clinical trial within 4
             weeks prior to randomization

          -  Exposure to oral or IV antibiotics within 2 weeks or live attenuated vaccines within 4
             weeks prior to randomization

          -  Prior treatment with cluster of differentiation (CD) 137 agonists or immune checkpoint
             blockade therapies, anti-programmed death-1 (anti-PD-1), and anti-PD-L1 therapeutic
             antibodies

          -  Treatment with immunostimulatory agents within 4 weeks or immunosuppressive agents
             within 2 weeks prior to randomization
      