['type 2 diabetes mellitus']
['opk-88003', 'placebo']

        Inclusion Criteria:

          -  Men or women aged 18 to 80 years with T2DM treated with diet and exercise alone or on
             a stable dose of metformin (≥ 1000 mg/day),

          -  BMI ≥27 and ≤45 kg/m2

          -  HbA1c ≥7.0% and ≤10.5% at screening

        Exclusion Criteria:

          -  Type 1 diabetes mellitus

          -  Previous treatment with incretin mimetic drugs

          -  Have used insulin for diabetic control for more than 6 consecutive days within the
             prior year

          -  Have had two or more emergency room visits or hospitalizations due to poor glucose
             control within the prior 6 months

          -  Have a history of acute or chronic pancreatitis or elevation in serum lipase/amylase
             (>2 x ULN).
      