['esophageal squamous cell carcinoma']
['fluorouracil', 'cisplatin']

        Inclusion Criteria:

          1. R0 resection for primary esophageal squamous cell carcinoma with two-incision
             esophagectomy (Ivor Lewis approach)25 or three-incision (right thoracotomy, midline
             laparotomy and left cervical incisions) esophagectomy with cervical esophagogastric
             anastomosis.

          2. Absence of previous thoracic radiotherapy.

          3. Cervical and/or thoracic postoperative recurrence (biopsy proven or positron emission
             tomography/computed tomography (PET/CT) proven or follow-up computed tomography (CT)
             showed progression of disease).

          4. Absence of distant metastasis at recurrence.

          5. Eastern Cooperative Oncology Group (ECOG) performance status (PS) ≤ 2

        Exclusion Criteria:

          1. Younger than 18 or older than 70 years of age.

          2. Eastern Cooperative Oncology Group (ECOG) performance status of 3 or above

          3. Other cancer history.

          4. Serious cardiac, liver, or pulmonary disease.

          5. Previous radiotherapy history
      