['systemic lupus erythematosus']
['matching placebo', 'cenerimod']

        Inclusion Criteria:

          -  Male and female participants aged 18 to 65 years with established SLE. Participants
             must have active SLE, Systemic Lupus Erythematosus Disease Activity Index-2000
             (SLEDAI-2K) score of at least 2 points for musculoskeletal or mucocutaneous
             manifestations and history or presence at screening of positive anti-nuclear
             antibodies (ANA) or anti-double-stranded DNA (anti-dsDNA) antibodies.

          -  Enrolled participants must be treated with background SLE medications.

        Exclusion Criteria:

          -  Participants with significant medical conditions or therapies for such conditions
             (e.g., cardiovascular, pulmonary, immunological, hepatic, ophthalmological, infection
             and infection risks, history or presence of malignancy, history or presence of bone
             marrow or solid organ transplantation) or lactating or pregnant women.

          -  Participants with severe SLE disease or with clinically relevant medical or surgical
             conditions that, in the opinion of the investigator, would put the subject at risk by
             participating in the study.
      