['allergic rhinitis']
['allert', 'placebo']

        Inclusion Criteria:

          -  Adult subjects 18 to 65 yrs old, male or female

          -  moderate to severe allergic Rhinitis/Rhinoconjunctivitis to birch pollen during the
             two preceding birch pollen seasons

          -  positive Skin Prick Test (SPT) to birch pollen extract

          -  positive specific IgE CAP to Bet v1.

        Exclusion Criteria:

          -  persistent non-controlled asthma (Forced Expiratory Volume, FEV1 < 85% of predicted),

          -  previous specific immunotherapy (SIT) to tree pollens,

          -  previous SIT to any allergen within 5 years,

          -  previous history of severe anaphylactic reaction,

          -  perennial allergic Rhinitis/Rhinoconjunctivitis,

          -  other disorder possibly influencing the trial outcomes,

          -  pregnancy,

          -  any severely debilitating disease,

          -  primary or secondary immunodeficiency or treatment with immunosuppressor drugs within
             one month prior to randomization (oral steroids, other immunosuppressors).
      