['tourette syndrome']
['sd-809']

        Inclusion Criteria:

          -  12 to 18 years of age, inclusive, at Screening.

          -  Patient has a Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition
             (DSM-V) diagnosis of Tourette Syndrome and has manifested motor and phonic tics within
             3 months before the Screening visit

          -  Patient has total tic score of ≥19 on the YGTSS

          -  Tic severity and frequency has been stable for at least 2 weeks before the Screening
             visit

          -  Willing to adhere to medication regimen and to comply with all procedures

          -  Patient is in good general health, as indicated by medical and psychiatric history and
             physical examination

          -  Patient and parent/guardian have provided written, informed consent (and written
             assent, as appropriate)

          -  Female patients of childbearing potential agree to use an acceptable method of
             contraception

               -  Additional criteria apply, please contact the investigator for more information

        Exclusion Criteria:

          -  Patient has a serious untreated or undertreated psychiatric illness

          -  Patient has a history of suicidal ideation or behavior

          -  Patient has received tetrabenazine, neuroleptics, benzodiazepines, topiramate,
             dopamine receptor antagonists within 14 days of Screening or Baseline; or botulinum
             toxin within 3 months of Screening or Baseline

          -  Patient is being treated with deep brain stimulation for control of tics

          -  Patient has a progressive or degenerative neurological disorder or a structural
             disorder of the brain

          -  Patient has participated in an investigational drug or device trial within 30 days of
             Screening

          -  Patient is pregnant or breastfeeding at Screening or Baseline

          -  Patient has a history of alcohol or substance abuse in the previous 12 months, as
             defined in the DSM-V

               -  Additional criteria apply, please contact the investigator for more information
      