['essential hypertension']
['cs-3150', 'placebo', 'eplerenone']

        Inclusion Criteria:

          -  Male and female subjects aged 20 years or older at informed consent

          -  Subjects with essential hypertension (Sitting SBP ≥ 140 mmHg and < 180 mmHg, Sitting
             DBP ≥ 90 mmHg and < 110 mmHg,and 24h-hr blood pressure more than 130 mmHg in SBP and
             80 mmHg in DBP)

        Exclusion Criteria:

          -  Secondary hypertension or malignant hypertension

          -  Diabetes mellitus with albuminuria

          -  Serum potassium level < 3.5 or ≥ 5.1 mEq/L

          -  Reversed day-night life cycle including overnight workers

          -  eGFR < 60 mL/min/1.73 m^2
      