['psoriasis vulgaris']
['leo 32731', 'leo 32731 placebo']

        Inclusion Criteria:

          -  Signed and dated informed consent

          -  Aged between 18 years and 65.

          -  Males or females of non-childbearing potential.

          -  Clinical diagnosis of psoriasis vulgaris with or without psoriatic arthritis

          -  Have moderate to severe psoriasis vulgaris

          -  Candidates of systemic anti-psoriatic treatment and/or phototherapy

        Exclusion Criteria:

          -  Subjects with therapy resistant psoriasis

          -  Previously exposed to apremilast

          -  Systemic treatment with biological therapies, whether marketed or not, with a possible
             effect on psoriasis vulgaris

          -  Systemic treatment with all other therapies (other than biologics) with a possible
             effect on psoriasis vulgaris
      