['suicidal ideation', 'major depressive disorder', 'healthy participants']
['ketamine', 'saline']

        Inclusion Criteria:

        Suicidal Ideation group:

          1. Any person admitted to the emergency room department after a suicide attempt , defined
             as requiring medical intervention - not just a psychiatrist ( surgical or
             pharmacological treatment but also the need for observation ) .

          2. The need for medical intervention will be defined by the ER ED physician

          3. Ages 18-65

        For the depression group:

          1. Diagnosed with major depression according to DSM VI.

          2. Ongoing depression (according to DSM criteria) despite treatment with at least two
             antidepressants in adequate dosages and for longer than three weeks.

          3. Ages 18-65

        For the romantic relationship breakup:

        1. Participants that have experienced a meaningful romantic relationship break-up within
        the past 12 months

        -

        Exclusion Criteria for all groups:

          1. Psychotic state instate in the examination

          2. Diagnosis of schizophrenia / schizoaffective disorder

          3. Drug or alcohol abuse as is revealed in by blood/urine tests

          4. Patient in which, according to the examiner, there is primary or secondary gain.

          5. Patient , which, at the time of his admission , is without any pharmacological
             treatment.
      