['chronic obstructive pulmonary disease']
['ypl-001 low dose', 'ypl-001 high dose', 'placebo']

        Inclusion Criteria:

          -  Adult males and/or females, 40 to 80 years of age (inclusive).

          -  History of COPD for at least 12 months prior to screening.

          -  Diagnosed with COPD as defined by the American Thoracic Society (ATS)/European
             Respiratory Society (ERS) guidelines with symptoms compatible with COPD for at least
             12 months prior to screening.

          -  Classified as moderate to severe COPD based on the current severity classification
             GOLD Stage 2-3 disease in terms of post-bronchodilator spirometry at screening

          -  etc.

        Exclusion Criteria:

          -  History of life-threatening COPD including respiratory arrest, intensive care unit
             admission and/or requiring intubation.

          -  History of more than 2 hospitalizations for COPD within 12 months prior to screening.

          -  Presentation of an acute exacerbation of COPD that will be associated with increase
             sputum volume or change in sputum color within 4 weeks before Day 1 of the Run-in
             Period.

          -  Evidence of pulmonary heart disease, or clinically significant pulmonary hypertension.

          -  etc.
      