
    5 immune related serious adverse events in phase 1 study
  
['melanoma']
['mrx34', 'dexamethasone']

        Inclusion Criteria:

          -  ≥18 years of age

          -  Advanced or metastatic cutaneous, acral or mucosal melanoma

          -  Tumor lesions accessible to serial biopsies

          -  ECOG ≤ 1

          -  ANC ≥, Plts ≥100,000 /mm3

        Exclusion Criteria:

          -  Serious active non-malignant disease

          -  Central Nervous System metastasis
      