
    lack of recruitment
  
['diabetic gastroparesis']
['promethazine', 'sugar pill']

        Inclusion Criteria:

          -  adult patients 18-65 years of age

          -  clinical diagnosis of diabetic gastroparesis.

          -  EGD without evidence of gastric outlet obstruction within the past five years

          -  gastric emptying scintigraphy test demonstrating >10% solid food retention at 4 hours
             within the past three years.

        Exclusion Criteria:

          -  the inability or unwillingness to provide informed consent

          -  currently pregnant or breast feeding

          -  prior placement of a gastric stimulator

          -  pyloric botulinum toxin injection within the past 12 months

          -  prior gastric surgery

          -  history of a connective tissue disorder

          -  use of narcotic medication within the past four weeks

          -  hemoglobin A1C >12 mg/dL within the past 3 months

          -  current or recent (within past 4 weeks) use of promethazine, metoclopramide or
             domperidone

          -  hypersensitivity or prior adverse reaction to promethazine

          -  concomitant use of phenothiazines (i.e. prochlorperazine, chlorpromazine) or other
             agents likely to increase extrapyramidal reactions

          -  concomitant use of tiotropium or ipratropium

          -  narrow angle glaucoma

          -  urinary retention

          -  Parkinson's disease

          -  significant psychiatric disease

          -  history of seizure.
      