['chronic idiopathic constipation']
['lubiprostone', 'placebo']

        Inclusion Criteria:

          -  Either has medically-confirmed diagnosis of chronic constipation (per Rome III), or
             meets the diagnosis as confirmed using the Rome III constipation module questionnaire
             during the Screening period.

          -  Is male or female, 18 or older years of age

          -  Should be on stable dose of fiber supplement or a concomitant medication for the
             indication of lowering blood pressure

        Exclusion Criteria:

          -  Has any gastrointestinal (GI) condition, other than constipation, affecting GI
             motility or defecation

          -  Is unable to eat or drink, take oral medications, or to hold down oral medications due
             to vomiting
      