This is T-cell surface glycoprotein CD3 gamma chain protein, from Crab-eating macaque, contains 181 amino acids, has 1 Ig-like Immunoglobulin domain.

Ig-like

Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response, When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z, All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain, Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of downstream signaling pathways, In addition to this role of signal transduction in T-cell activation, CD3G plays an essential role in the dynamic regulation of TCR expression at the cell surface, Indeed, constitutive TCR cycling is dependent on the di-leucine-based (diL) receptor-sorting motif present in CD3G


This is Zip homologous protein 1 protein, from Caenorhabditis elegans, contains 220 amino acids, has 1 RING-type Zinc finger.

RING-type

Recruited co-dependently with zhp-2 to the synaptonemal complex between homologous chromosome pairs to regulate the formation and number of crossover events between homologs during meiotic recombination (PubMed:29521627), Together with zhp-2, promotes the accumulation of pro-crossover proteins, including zhp-3 and zhp-4, at a designated crossover site along the recombination intermediate (PubMed:29521627), Limits the number of crossover sites along a recombination intermediate by restricting the association of these pro-crossover proteins with other recombination sites during late prophase (PubMed:29521627), Also, together with zhp-2, plays a role in chromosome remodeling following crossover formation to promote two successive rounds of chromosome segregation during meiosis (PubMed:29521627)


This is E3 ubiquitin-protein ligase Kcmf1 protein, from Fruit fly, contains 599 amino acids, has 1 ZZ-type Zinc finger, has 1 C2H2-type Zinc finger.

ZZ-type

Has intrinsic E3 ubiquitin ligase activity and promotes ubiquitination, Involved in the negative regulation of the Ras/MAPK signaling pathway in the wing by acting with the E2 enzyme Unc6 and the putative E3 ligases poe and Ufd4 to mediate the ubiquitination and proteasomal degradation of rl/MAPK


This is REST corepressor rcor-1 protein, from Caenorhabditis elegans, contains 564 amino acids, has 1 GATA-type Zinc finger.

GATA-type

Probable corepressor protein acting as a component of a complex that represses transcription (Probable), May play a role, as part of a CoREST-like complex, together with the chromobox protein homologs hpl-1 and hpl-2, in the formation of the vulva and in fertility (PubMed:26476455)


This is Fibroblast growth factor receptor protein, from Sea squirt, contains 763 amino acids, has 2 Ig-like C2-type Immunoglobulin domain.

Ig-like C2-type

Ig-like C2-type

Receptor for basic fibroblast growth factor

Belongs to the protein kinase superfamily, Tyr protein kinase family, Fibroblast growth factor receptor subfamily


This is Zinc finger protein CONSTANS-LIKE 2 protein, from Mouse-ear cress, contains 347 amino acids, has 1 B box-type 1; atypical Zinc finger, has 1 B box-type 2; atypical Zinc finger.

B box-type 1; atypical

B box-type 2; atypical

Putative transcription factor, Does not affect flowering time


This is DNA-directed RNA polymerase II subunit rpb-9 protein, from Caenorhabditis elegans, contains 167 amino acids, has 1 C4-type Zinc finger, has 1 TFIIS-type Zinc finger.

TFIIS-type

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity), Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs (Probable), Pol II is the central component of the basal RNA polymerase II transcription machinery (By similarity), It is composed of mobile elements that move relative to each other (By similarity), RPB9 is part of the upper jaw surrounding the central large cleft and thought to grab the incoming DNA template (By similarity), Recruits ints-6, a component of the Integrator complex to PIWI-interacting RNA (piRNA) genes, to mediate Integrator complex-dependent cleavage of 3' ends of nascent transcripts upon RNA Pol II backtracking to terminate transcription and generate piRNA precursors (PubMed:33533030), Promotes the biogenesis of secondary 22G-siRNAs (a class of 22 nucleotide siRNAs that possess a triphosphorylated guanine residue at the 5'-end) (PubMed:33533030), Involved in gene silencing mediated by a class of 21 nucleotide piRNAs that possess a uracil residue at the 5'-end (also called 21U-RNAs) and guide the Piwi protein prg-1 to its DNA targets for silencing (PubMed:33533030), Plays a role in small RNA-directed transgenerational epigenetic inheritance (also called RNAe) over several generations (PubMed:33533030), Not required for the transgenerational inheritance of exogenous small interfering RNAs (RNAi) (PubMed:33533030), May play a role in the silencing of the DNA transposable elements from the DNA transposon families, Chapaev-2 and CEMUDR1 (PubMed:33533030)

Belongs to the archaeal RpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family


This is E3 ubiquitin-protein ligase siah-1 protein, from Caenorhabditis elegans, contains 419 amino acids, has 1 RING-type; degenerate Zinc finger, has 1 SIAH-type; degenerate Zinc finger.

RING-type; degenerate

SIAH-type; degenerate

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins, E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, It probably triggers the ubiquitin-mediated degradation of different substrates

Belongs to the SINA (Seven in absentia) family


This is Transcriptional activator protein protein, from CaLCuV, contains 129 amino acids, has 1  Zinc finger.

Strong activator of the late viral genes promoters, Enhances the expression of the capsid protein and nuclear shuttle protein, Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs, Suppresses the host RNA silencing by inhibiting adenosine kinase 2 (ADK2), a kinase involved in a general methylation pathway, Also suppresses the host basal defense by interacting with and inhibiting SNF1 kinase, a key regulator of cell metabolism implicated in innate antiviral defense, Determines pathogenicity (By similarity)

Belongs to the geminiviridae transcriptional activator protein family


This is Zinc finger protein 566 protein, from Human, contains 418 amino acids, has 1 C2H2-type 1; degenerate Zinc finger, has 7 C2H2-type Zinc finger.

C2H2-type 1; degenerate

May be involved in transcriptional regulation

Belongs to the krueppel C2H2-type zinc-finger protein family


This is SLAM family member 9 protein, from Human, contains 289 amino acids, has 1 Ig-like V-type Immunoglobulin domain, has 1 Ig-like C2-type Immunoglobulin domain.

Ig-like V-type

Ig-like C2-type


This is Tripartite motif-containing protein 43 protein, from Human, contains 446 amino acids, has 1 RING-type Zinc finger, has 1 B box-type Zinc finger.

RING-type

B box-type

E3 ligase that regulates nuclear lamina integrity and the association of viral chromatin with transcriptionally-active host chromatin, Acts thereby as a herpesvirus-specific antiviral factor and mediates the ubiquitination-dependent proteasomal degradation of PCNT

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome


This is Zinc finger protein 775 protein, from Human, contains 537 amino acids, has 11 C2H2-type Zinc finger.


This is Zinc finger protein 707 protein, from Human, contains 371 amino acids, has 7 C2H2-type Zinc finger.


This is Zinc finger protein 501 protein, from Human, contains 271 amino acids, has 9 C2H2-type Zinc finger.

May be involved in transcriptional regulation, Essential for Golgi structural integrity (PubMed:29851555)


This is RING finger and SPRY domain-containing protein 1 protein, from Human, contains 576 amino acids, has 1 RING-type Zinc finger.

RING-type


This is E3 ubiquitin-protein ligase NEURL3 protein, from Human, contains 262 amino acids, has 1 RING-type Zinc finger.

RING-type

E3 ubiquitin-protein ligase that plays a role in various biological processes such as lung development or innate immunity (PubMed:30111563), Seems to utilize UBE2E1, Promotes innate antiviral response by catalyzing 'Lys-63'-linked ubiquitination of IRF7 (PubMed:35792897), Inhibits also hepatitis C virus assembly by directly binding to viral E1 envelope glycoprotein to disrupt its interaction with E2 (PubMed:30111563)


This is RING finger and transmembrane domain-containing protein 2 protein, from Human, contains 444 amino acids, has 1 RING-type Zinc finger.

RING-type


This is Zinc finger C2HC domain-containing protein 1A protein, from Human, contains 325 amino acids, has 1 C2HC-type Zinc finger.


This is Zinc finger protein 419 protein, from Human, contains 510 amino acids, has 11 C2H2-type Zinc finger.


This is Kazal-type serine protease inhibitor domain-containing protein 1 protein, from Human, contains 304 amino acids, has 1 Ig-like C2-type Immunoglobulin domain.

Ig-like C2-type

Involved in the proliferation of osteoblasts during bone formation and bone regeneration, Promotes matrix assembly (By similarity)

Secreted, extracellular space, extracellular matrix


This is V-set and immunoglobulin domain-containing protein 2 protein, from Human, contains 327 amino acids, has 1 Ig-like V-type Immunoglobulin domain, has 1 Ig-like C2-type Immunoglobulin domain.

Ig-like V-type

Ig-like C2-type


This is Zinc finger protein 479 protein, from Human, contains 524 amino acids, has 12 C2H2-type Zinc finger.


This is Zinc finger and SCAN domain-containing protein 31 protein, from Human, contains 406 amino acids, has 6 C2H2-type Zinc finger.

May function as a transcription factor, May be involved in the development of multiple embryonic organs


This is RING finger protein 145 protein, from Human, contains 663 amino acids, has 1 RING-type; atypical Zinc finger.

RING-type; atypical

E3 ubiquitin ligase that catalyzes the direct transfer of ubiquitin from E2 ubiquitin-conjugating enzyme to a specific substrate, In response to bacterial infection, negatively regulates the phagocyte oxidative burst by controlling the turnover of the NADPH oxidase complex subunits, Promotes monoubiquitination of CYBA and 'Lys-48'-linked polyubiquitination and degradation of CYBB NADPH oxidase catalytic subunits, both essential for the generation of antimicrobial reactive oxygen species, Involved in the maintenance of cholesterol homeostasis, In response to high sterol concentrations ubiquitinates HMGCR, a rate-limiting enzyme in cholesterol biosynthesis, and targets it for degradation, The interaction with INSIG1 is required for this function, In addition, triggers ubiquitination of SCAP, likely inhibiting its transport to the Golgi apparatus and the subsequent processing/maturation of SREBPF2, ultimately down-regulating cholesterol biosynthesis


This is Zinc finger protein 714 protein, from Human, contains 554 amino acids, has 1 C2H2-type 1; degenerate Zinc finger, has 12 C2H2-type Zinc finger, has 1 C2H2-type 14; degenerate Zinc finger.

C2H2-type 1; degenerate

C2H2-type 14; degenerate


This is Zinc finger protein 599 protein, from Human, contains 588 amino acids, has 14 C2H2-type Zinc finger.


This is Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3 protein, from Human, contains 834 amino acids, has 1 C4-type Zinc finger.

GTPase-activating protein for the ADP ribosylation factor family


This is Zinc finger imprinted 3 protein, from Human, contains 472 amino acids, has 11 C2H2-type Zinc finger.


This is Zinc finger protein 347 protein, from Human, contains 839 amino acids, has 1 C2H2-type 1; degenerate Zinc finger, has 17 C2H2-type Zinc finger, has 1 C2H2-type 14; degenerate Zinc finger, has 1 C2H2-type 20; degenerate Zinc finger.

C2H2-type 1; degenerate

C2H2-type 14; degenerate

C2H2-type 20; degenerate


This is Zinc finger protein 607 protein, from Human, contains 696 amino acids, has 18 C2H2-type Zinc finger, has 1 C2H2-type 2; degenerate Zinc finger, has 1 C2H2-type 8; degenerate Zinc finger.

C2H2-type 2; degenerate

C2H2-type 8; degenerate


This is Flt3-interacting zinc finger protein 1 protein, from Human, contains 496 amino acids, has 11 C2H2-type Zinc finger.

May be a transcriptional repressor of NRL function in photoreceptors, Does not repress CRX-mediated transactivation (By similarity)


This is Zinc finger protein 382 protein, from Human, contains 550 amino acids, has 1 C2H2-type 1; degenerate Zinc finger, has 9 C2H2-type Zinc finger.

C2H2-type 1; degenerate

Functions as a sequence-specific transcriptional repressor


This is Zinc finger protein ZIC 5 protein, from Human, contains 663 amino acids, has 1 C2H2-type 1; atypical Zinc finger, has 3 C2H2-type Zinc finger.

C2H2-type 1; atypical

Essential for neural crest development, converting cells from an epidermal fate to a neural crest cell fate, Binds to DNA (By similarity)

Belongs to the GLI C2H2-type zinc-finger protein family


This is Insulinoma-associated protein 2 protein, from Human, contains 566 amino acids, has 1 C2H2-type 1; atypical Zinc finger, has 4 C2H2-type Zinc finger.

C2H2-type 1; atypical

May function as a growth suppressor or tumor suppressor in liver cells and in certain neurons


This is Alpha-aminoadipate/glutamate carrier protein LysW protein, from Sulfolobus tokodaii, contains 56 amino acids, has 1 TFIIB-type Zinc finger.

TFIIB-type

Carrier protein that bears the covalently bound substrates for arginine and lysine biosynthesis; bound L-glutamate is sequentially converted to L-ornithine, while bound alpha-aminoadipate (AAA) is sequentially converted to L-lysine


This is Transcription factor S1 protein, from Sulfolobus solfataricus, contains 114 amino acids, has 1 TFIIS-type Zinc finger.

TFIIS-type

Induces RNA cleavage activity in the RNA polymerase, Induces rapid cleavage of a stalled transcription elongation complex with a 2-nucleotide reduction at the 3' end of the nascent RNA, Truncated RNA is able to resume elongation, During transcription elongation it enhances processivity (PubMed:29203770), Involved in transcriptional proofreading and fidelity, Misincorporation of nucleotides during elongation of transcription leads to arrested elongation complexes which are rescued by TFS-promoted removal of a dinucleotide from the 3'-end, TFS1 is able to induce a cleavage resynthesis cycle in stalled elongation complexes (resulting from the next missing nucleotide or a reduced incorporation rate of a wrong nucleotide) preventing misincorporation and enabling proofreading in a post-incorporation manner, Pausing of elongation complexes is the main determinant of TFS-induced RNA cleavage (By similarity)


This is Zinc finger protein GLIS2 protein, from African clawed frog, contains 492 amino acids, has 4 C2H2-type Zinc finger, has 1 C2H2-type 2; degenerate Zinc finger.

C2H2-type 2; degenerate

Can act either as a transcription repressor or as a transcription activator, depending on the cell context, May be involved in neuron differentiation


This is Peroxisomal biogenesis factor 2 protein, from Yeast, contains 381 amino acids, has 1 RING-type Zinc finger.

RING-type

E3 ubiquitin-protein ligase component of a retrotranslocation channel required for peroxisome organization by mediating export of the PEX5 receptor from peroxisomes to the cytosol, thereby promoting PEX5 recycling, The retrotranslocation channel is composed of PEX2, PEX10 and PEX12; each subunit contributing transmembrane segments that coassemble into an open channel that specifically allows the passage of PEX5 through the peroxisomal membrane, PEX2 also regulates peroxisome organization by acting as a E3 ubiquitin-protein ligase, PEX2 ubiquitinates PEX5 during its passage through the retrotranslocation channel: catalyzes monoubiquitination of PEX5 at 'Cys-6', a modification that acts as a signal for PEX5 extraction into the cytosol


This is E3 ubiquitin-protein ligase LAP protein, from MYXV, contains 206 amino acids, has 1 RING-CH-type Zinc finger.

RING-CH-type

E3 ubiquitin-protein ligase which promotes ubiquitination and subsequent degradation of host MHC-I and CD4 molecules, presumably to prevent lysis of infected cells by cytotoxic T-lymphocytes and NK cell, Binds target molecules through transmembrane interaction, The result of this ubiquitination is the enhancement of the endocytosis of the target chain and the delivery to the lysosome, where it is proteolytically destroyed (By similarity)

Belongs to the poxviridae LAP protein family


This is Differentially expressed in FDCP 8 protein, from Mouse, contains 448 amino acids, has 2 Phorbol-ester/DAG-type Zinc finger.

Phorbol-ester/DAG-type

Phorbol-ester/DAG-type

Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts (PubMed:27777970), Involved in bone resorption (PubMed:27777970)


This is Zinc finger protein 639 protein, from Mouse, contains 485 amino acids, has 8 C2H2-type Zinc finger.

Binds DNA and may function as a transcriptional repressor


This is YY1-associated factor 2 protein, from Mouse, contains 179 amino acids, has 1 RanBP2-type Zinc finger.

Binds to MYC and inhibits MYC-mediated transactivation, Also binds to MYCN and enhances MYCN-dependent transcriptional activation, Increases calpain 2-mediated proteolysis of YY1 in vitro, Component of the E2F6,com-1 complex, a repressive complex that methylates 'Lys-9' of histone H3, suggesting that it is involved in chromatin-remodeling


This is Transcriptional repressor scratch 1 protein, from Mouse, contains 348 amino acids, has 4 C2H2-type Zinc finger, has 1 C2H2-type 5; atypical Zinc finger.

C2H2-type 5; atypical

Transcriptional repressor that binds E-box motif CAGGTG (By similarity), Appears to function downstream of proneural bHLH proteins in promoting neural differentiation

Belongs to the snail C2H2-type zinc-finger protein family


This is RING finger protein 141 protein, from Mouse, contains 230 amino acids, has 1 RING-type Zinc finger.

RING-type


This is Basigin protein, from Chinese hamster, contains 249 amino acids, has 1 Ig-like C2-type Immunoglobulin domain, has 1 Ig-like V-type Immunoglobulin domain.

Ig-like C2-type

Ig-like V-type

Signaling receptor for cyclophilins, essential for PPIA/CYPA and PPIB/CYPB-dependent signaling related to chemotaxis and adhesion of immune cells (By similarity), Plays an important role in targeting the monocarboxylate transporters SLC16A1/GLUT1, SLC16A3, SLC16A8, SLC16A11 and SLC16A12 to the plasma membrane (By similarity), Acts as a coreceptor for vascular endothelial growth factor receptor 2 (KDR/VEGFR2) in endothelial cells enhancing its VEGFA-mediated activation and downstream signaling (By similarity), Promotes angiogenesis through EPAS1/HIF2A-mediated up-regulation of VEGFA and KDR/VEGFR2 in endothelial cells (By similarity)


This is E3 ubiquitin-protein ligase RNF138 protein, from Rat, contains 209 amino acids, has 1 RING-type Zinc finger, has 1 C2HC RNF-type Zinc finger, has 1 C2H2-type Zinc finger.

RING-type

C2HC RNF-type

E3 ubiquitin-protein ligase involved in DNA damage response by promoting DNA resection and homologous recombination, Recruited to sites of double-strand breaks following DNA damage and specifically promotes double-strand break repair via homologous recombination, Two different, non-exclusive, mechanisms have been proposed, According to a report, regulates the choice of double-strand break repair by favoring homologous recombination over non-homologous end joining (NHEJ): acts by mediating ubiquitination of XRCC5/Ku80, leading to remove the Ku complex from DNA breaks, thereby promoting homologous recombination, According to another report, cooperates with UBE2Ds E2 ubiquitin ligases (UBE2D1, UBE2D2, UBE2D3 or UBE2D4) to promote homologous recombination by mediating ubiquitination of RBBP8/CtIP, Together with NLK, involved in the ubiquitination and degradation of TCF/LEF, Also exhibits auto-ubiquitination activity in combination with UBE2K, May act as a negative regulator in the Wnt/beta-catenin-mediated signaling pathway


This is Neurotrimin protein, from Mouse, contains 344 amino acids, has 3 Ig-like C2-type Immunoglobulin domain.

Ig-like C2-type

Ig-like C2-type

Ig-like C2-type

Belongs to the immunoglobulin superfamily, IgLON family


This is DNA topoisomerase 1 protein, from Staphylococcus aureus (strain Mu50 / ATCC 700699), contains 689 amino acids, has 3 C4-type Zinc finger.

Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex, Introduces a single-strand break via transesterification at a target site in duplex DNA, The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand, The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils, Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone

Belongs to the type IA topoisomerase family


This is Formamidopyrimidine-DNA glycosylase protein, from Caulobacter crescentus, contains 287 amino acids, has 1 FPG-type Zinc finger.

FPG-type

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents, Acts as DNA glycosylase that recognizes and removes damaged bases, Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG), Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand, Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates


This is Ubiquitin-ribosomal protein eS31z fusion protein protein, from Rice, contains 155 amino acids, has 1 C4-type Zinc finger.

Component of the 40S subunit of the ribosome

In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family


This is Major histocompatibility complex class I-related gene protein protein, from Bornean orangutan, contains 340 amino acids, has 1 Ig-like C1-type Immunoglobulin domain.

Ig-like C1-type

Antigen-presenting molecule specialized in displaying microbial pyrimidine-based metabolites to alpha-beta T cell receptors (TCR) on innate-type mucosal-associated invariant T (MAIT) cells, In complex with B2M preferentially presents riboflavin-derived metabolites to semi-invariant TCRs on MAIT cells, guiding immune surveillance of the microbial metabolome at mucosal epithelial barriers (By similarity), Signature pyrimidine-based microbial antigens are generated via non-enzymatic condensation of metabolite intermediates of the riboflavin pathway with by-products arising from other metabolic pathways such as glycolysis, Typical potent antigenic metabolites are 5-(2-oxoethylideneamino)-6-D-ribitylaminouracil (5-OE-RU) and 5-(2-oxopropylideneamino)-6-D-ribitylaminouracil (5-OP-RU), products of condensation of 5-amino-6-D-ribityaminouracil (5-A-RU) with glyoxal or methylglyoxal by-products, respectively (By similarity), May present microbial antigens to various MAIT cell subsets, providing for unique recognition of diverse microbes, including pathogens that do not synthesize riboflavin, Upon antigen recognition, elicits rapid innate-type MAIT cell activation to eliminate pathogenic microbes by directly killing infected cells (By similarity), During T cell development, drives thymic selection and post-thymic terminal differentiation of MAIT cells in a process dependent on commensal microflora (By similarity), Acts as an immune sensor of cancer cell metabolome, May present a tumor-specific or -associated metabolite essential for cancer cell survival to a pan-cancer TCR on a non-MAIT CD8-positive T cell clone, triggering T cell-mediated killing of a wide range of cancer cell types (By similarity)


This is Aprataxin protein, from Crab-eating macaque, contains 356 amino acids, has 1 C2H2-type Zinc finger.

DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair, Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species, Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'-phosphate termini that can be efficiently rejoined, Also able to hydrolyze adenosine 5'-monophosphoramidate (AMP-NH(2)) and diadenosine tetraphosphate (AppppA), but with lower catalytic activity (By similarity), Likewise, catalyzes the release of 3'-linked guanosine (DNAppG) and inosine (DNAppI) from DNA, but has higher specific activity with 5'-linked adenosine (AppDNA) (By similarity)


This is CD166 antigen protein, from Bovine, contains 583 amino acids, has 2 Ig-like V-type Immunoglobulin domain, has 3 Ig-like C2-type Immunoglobulin domain.

Ig-like V-type

Ig-like V-type

Ig-like C2-type

Ig-like C2-type

Ig-like C2-type

Cell adhesion molecule that mediates both heterotypic cell-cell contacts via its interaction with CD6, as well as homotypic cell-cell contacts, Promotes T-cell activation and proliferation via its interactions with CD6 (By similarity), Contributes to the formation and maturation of the immunological synapse via its interactions with CD6 (By similarity), Mediates homotypic interactions with cells that express ALCAM, Mediates attachment of dendritic cells onto endothelial cells via homotypic interaction, Inhibits endothelial cell migration and promotes endothelial tube formation via homotypic interactions, Required for normal organization of the lymph vessel network, Required for normal hematopoietic stem cell engraftment in the bone marrow, Plays a role in hematopoiesis; required for normal numbers of hematopoietic stem cells in bone marrow, Promotes in vitro osteoblast proliferation and differentiation (By similarity), Promotes neurite extension, axon growth and axon guidance; axons grow preferentially on surfaces that contain ALCAM (By similarity), Mediates outgrowth and pathfinding for retinal ganglion cell axons (By similarity)


This is Receptor-transporting protein 3 protein, from Human, contains 232 amino acids, has 1 3CxxC-type Zinc finger.

Promotes functional cell surface expression of the bitter taste receptors TAS2R16 and TAS2R43


This is Zinc finger protein 559 protein, from Human, contains 538 amino acids, has 1 C2H2-type 1; degenerate Zinc finger, has 1 C2H2-type 2; degenerate Zinc finger, has 1 C2H2-type 3; degenerate Zinc finger, has 1 C2H2-type 4; degenerate Zinc finger, has 9 C2H2-type Zinc finger.

C2H2-type 1; degenerate

C2H2-type 2; degenerate

C2H2-type 3; degenerate

C2H2-type 4; degenerate

May be involved in transcriptional regulation


This is Zinc finger protein 649 protein, from Human, contains 505 amino acids, has 10 C2H2-type Zinc finger.

Transcriptional repressor, Regulator of transcriptional factor complexes and may suppress SRE and AP-1 transcription activities mediated by growth factor signaling pathways


This is Zinc finger protein 577 protein, from Human, contains 485 amino acids, has 1 C2H2-type 1; degenerate Zinc finger, has 7 C2H2-type Zinc finger.

C2H2-type 1; degenerate


This is Zinc finger and SCAN domain-containing protein 5A protein, from Human, contains 496 amino acids, has 5 C2H2-type Zinc finger.


This is Zinc finger protein 471 protein, from Human, contains 626 amino acids, has 15 C2H2-type Zinc finger.


This is Krueppel-like factor 16 protein, from Human, contains 252 amino acids, has 3 C2H2-type Zinc finger.

Transcription factor that binds GC and GT boxes and displaces Sp1 and Sp3 from these sequences, Modulates dopaminergic transmission in the brain (By similarity)

Belongs to the Sp1 C2H2-type zinc-finger protein family


This is Probable ribonuclease ZC3H12C protein, from Human, contains 883 amino acids, has 1 C3H1-type Zinc finger.

May function as RNase and regulate the levels of target RNA species


This is Probable E3 ubiquitin-protein ligase ARI16 protein, from Mouse-ear cress, contains 500 amino acids, has 1 RING-type Zinc finger, has 1 IBR-type Zinc finger, has 1 RING-type 2; atypical Zinc finger, has 1 RanBP2-type Zinc finger.

RING-type

IBR-type

RING-type 2; atypical

Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates

Belongs to the RBR family, Ariadne subfamily


This is Putative E3 ubiquitin-protein ligase ORTHRUS 4 protein, from Mouse-ear cress, contains 622 amino acids, has 1 PHD-type Zinc finger, has 2 RING-type Zinc finger.

PHD-type

RING-type

RING-type

E3 ubiquitin-protein ligase, May participate in CpG methylation-dependent transcriptional regulation (By similarity)


This is Zinc finger protein CONSTANS-LIKE 7 protein, from Mouse-ear cress, contains 392 amino acids, has 1 B box-type; atypical Zinc finger.

B box-type; atypical


This is E3 ubiquitin-protein ligase SINA-like 4 protein, from Mouse-ear cress, contains 329 amino acids, has 1 RING-type; degenerate Zinc finger, has 1 SIAH-type Zinc finger.

RING-type; degenerate

SIAH-type

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins, E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, It probably triggers the ubiquitin-mediated degradation of different substrates


This is Zinc finger CCCH domain-containing protein 14 protein, from Mouse-ear cress, contains 310 amino acids, has 2 C3H1-type Zinc finger.

Functions probably as a transcriptional factor that activates genes involved in secondary cell wall biosynthesis (PubMed:25228083, PubMed:25732536), May play a role in both transcriptional and post-transcriptional regulation (PubMed:25228083), Binds to ssDNA, dsDNA, and ribohomopolymers in vitro (PubMed:25228083), Maybe involved in post-transcriptional regulation of its target genes (PubMed:25228083), Targets RNA of a polygalacturonase, a well-known cell wall modifying gene (PubMed:25228083), Functions redudantly with C3H15 to regulate secondary cell wall formation (PubMed:25732536), C3H14 and C3H15 have overlapping roles in the regulation of secondary cell wall formation and anther development (PubMed:25732536), C3H14 may contribute more to secondary cell wall thickening while C3H15 could be more important in anther development (PubMed:25732536), May regulate at both the transcriptional and post-transcriptional levels the expression of many genes involved in various biological processes, particularly those associated with cell wall metabolism and pollen development (PubMed:25732536)


This is DNA topoisomerase 1 protein, from Streptococcus lactis, contains 710 amino acids, has 2 C4-type Zinc finger, has 1 C4-type 3; atypical Zinc finger.

C4-type 3; atypical


This is DNA topoisomerase 1 protein, from Pasteurella multocida (strain Pm70), contains 868 amino acids, has 3 C4-type Zinc finger.


This is Anaphase-promoting complex subunit 11 protein, from Mouse, contains 84 amino acids, has 1 RING-type Zinc finger.

RING-type

Together with the cullin protein ANAPC2, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle, The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains, May recruit the E2 ubiquitin-conjugating enzymes to the complex (By similarity)


This is E3 ubiquitin-protein ligase RNF138 protein, from Mouse, contains 245 amino acids, has 1 RING-type Zinc finger, has 1 C2HC RNF-type Zinc finger, has 2 C2H2-type Zinc finger.

RING-type

C2HC RNF-type

E3 ubiquitin-protein ligase involved in DNA damage response by promoting DNA resection and homologous recombination, Recruited to sites of double-strand breaks following DNA damage and specifically promotes double-strand break repair via homologous recombination, Two different, non-exclusive, mechanisms have been proposed, According to a report, regulates the choice of double-strand break repair by favoring homologous recombination over non-homologous end joining (NHEJ): acts by mediating ubiquitination of XRCC5/Ku80, leading to remove the Ku complex from DNA breaks, thereby promoting homologous recombination, According to another report, cooperates with UBE2Ds E2 ubiquitin ligases (UBE2D1, UBE2D2, UBE2D3 or UBE2D4) to promote homologous recombination by mediating ubiquitination of RBBP8/CtIP, Together with NLK, involved in the ubiquitination and degradation of TCF/LEF, Also exhibits auto-ubiquitination activity in combination with UBE2K, May act as a negative regulator in the Wnt/beta-catenin-mediated signaling pathway


This is Zinc finger MYND domain-containing protein 19 protein, from Mouse, contains 227 amino acids, has 1 MYND-type; degenerate Zinc finger.

MYND-type; degenerate

May be involved as a regulatory molecule in GPR24/MCH-R1 signaling


This is Zinc finger and BTB domain-containing protein 8A protein, from Mouse, contains 434 amino acids, has 2 C2H2-type Zinc finger.


This is PR domain zinc finger protein 5 protein, from Mouse, contains 599 amino acids, has 14 C2H2-type Zinc finger, has 1 C2H2-type 13; degenerate Zinc finger.

C2H2-type 13; degenerate

Sequence-specific DNA-binding transcription factor, Represses transcription at least in part by recruitment of the histone methyltransferase EHMT2/G9A and histone deacetylases such as HDAC1, Regulates hematopoiesis-associated protein-coding and microRNA (miRNA) genes (By similarity), May regulate the expression of proteins involved in extracellular matrix development and maintenance, connective tissue components and molecules regulating cell migration and adhesion, May cause G2/M arrest and apoptosis in cancer cells (By similarity)

Belongs to the class V-like SAM-binding methyltransferase superfamily


This is E3 ubiquitin-protein ligase RNF181 protein, from Mouse, contains 165 amino acids, has 1 RING-type; atypical Zinc finger.

RING-type; atypical

E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, Catalyzes monoubiquitination of 26S proteasome subunit PSMC2/RPT1


This is Zinc finger CCHC domain-containing protein 8 protein, from Mouse, contains 709 amino acids, has 1 CCHC-type Zinc finger.

CCHC-type

Scaffolding subunit of the trimeric nuclear exosome targeting (NEXT) complex that is involved in the surveillance and turnover of aberrant transcripts and non-coding RNAs, NEXT functions as an RNA exosome cofactor that directs a subset of non-coding short-lived RNAs for exosomal degradation, May be involved in pre-mRNA splicing, It is required for 3'-end maturation of telomerase RNA component (TERC), TERC 3'-end targeting to the nuclear RNA exosome, and for telomerase function


This is General transcription factor IIE subunit 1 protein, from Mouse, contains 440 amino acids, has 1 C4-type Zinc finger.

Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH, Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase

Belongs to the TFIIE alpha subunit family


This is Zinc finger protein 706 protein, from Mouse, contains 76 amino acids, has 1 C2H2-type Zinc finger.

Transcription repressor involved in the exit of embryonic stem cells (ESCs) from self-renewal, Acts by repressing expression of KLF4


This is Target of EGR1 protein 1 protein, from Mouse, contains 511 amino acids, has 1 C3H1-type Zinc finger.

Inhibits cell growth rate and cell cycle, Induces CDKN1A expression as well as TGF-beta expression, Mediates the inhibitory growth effect of EGR1, Involved in the maturation of snRNAs and snRNA 3'-tail processing


This is V-set and immunoglobulin domain-containing protein 1 protein, from Mouse, contains 407 amino acids, has 1 Ig-like V-type Immunoglobulin domain, has 1 Ig-like C2-type Immunoglobulin domain.

Ig-like V-type

Ig-like C2-type


This is Microfibrillar-associated protein 3-like protein, from Mouse, contains 409 amino acids, has 1 Ig-like C2-type Immunoglobulin domain.

Ig-like C2-type

May participate in the nuclear signaling of EGFR and MAPK1/ERK2


This is Splicing factor 3A subunit 3 protein, from Mouse, contains 501 amino acids, has 1 Matrin-type Zinc finger.

Matrin-type

Involved in pre-mRNA splicing as a component of the splicing factor SF3A complex that contributes to the assembly of the 17S U2 snRNP, and the subsequent assembly of the pre-spliceosome 'E' complex and the pre-catalytic spliceosome 'A' complex, Involved in pre-mRNA splicing as a component of pre-catalytic spliceosome 'B' complexes


This is Non-structural maintenance of chromosomes element 1 homolog protein, from Mouse, contains 266 amino acids, has 1 RING-type; atypical Zinc finger.

RING-type; atypical

RING-type zinc finger-containing E3 ubiquitin ligase that assembles with melanoma antigen protein (MAGE) to catalyze the direct transfer of ubiquitin from E2 ubiquitin-conjugating enzyme to a specific substrate, Within MAGE-RING ubiquitin ligase complex, MAGE stimulates and specifies ubiquitin ligase activity likely through recruitment and/or stabilization of the E2 ubiquitin-conjugating enzyme at the E3:substrate complex, Involved in maintenance of genome integrity, DNA damage response and DNA repair, NSMCE3/MAGEG1 and NSMCE1 ubiquitin ligase are components of SMC5-SMC6 complex and may positively regulate homologous recombination-mediated DNA repair


This is ADP-ribosylation factor GTPase-activating protein 3 protein, from Mouse, contains 523 amino acids, has 1 C4-type Zinc finger.

GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1), Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes (By similarity)


This is Zinc finger and BTB domain-containing protein 43 protein, from Mouse, contains 467 amino acids, has 1 C2H2-type 1; atypical Zinc finger, has 1 C2H2-type Zinc finger, has 1 C2H2-type 3; atypical Zinc finger.

C2H2-type 1; atypical

C2H2-type 3; atypical

May be involved in transcriptional regulation


This is Gametocyte-specific factor 1 protein, from Mouse, contains 167 amino acids, has 2 CHHC U11-48K-type Zinc finger.

CHHC U11-48K-type

CHHC U11-48K-type

Required for spermatogenesis and is involved in the suppression of retrotransposon transcription in male germ cells


This is Zinc finger protein 580 protein, from Mouse, contains 172 amino acids, has 3 C2H2-type Zinc finger.

Involved in the regulation of endothelial cell proliferation and migration, Mediates H(2)O(2)-induced leukocyte chemotaxis by elevating interleukin-8 production and may play a role in inflammation, May be involved in transcriptional regulation (By similarity)


This is Zinc finger protein 593 protein, from Mouse, contains 134 amino acids, has 1 C2H2-type Zinc finger.

Involved in pre-60S ribosomal particles maturation by promoting the nuclear export of the 60S ribosome, Negatively modulates the DNA binding activity of Oct-2 and therefore its transcriptional regulatory activity

Belongs to the ZNF593/BUD20 C2H2-type zinc-finger protein family


This is Probable ATP-dependent RNA helicase DDX59 protein, from Mouse, contains 619 amino acids, has 1 HIT-type Zinc finger.

HIT-type

Belongs to the DEAD box helicase family, DDX59 subfamily


This is E3 ubiquitin-protein ligase makorin-2 protein, from Five-ray yellowtail, contains 423 amino acids, has 4 C3H1-type Zinc finger, has 1 RING-type Zinc finger.

RING-type

E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins (By similarity), Inhibits neurogenesis and axis formation during embryonic development by modulating the phosphatidylinositol 3-kinase (PI3K) pathway, Acts downstream of PI3K and akt1 to up-regulate gsk3b mRNA expression


This is E3 ubiquitin-protein ligase makorin-2 protein, from Zebrafish, contains 414 amino acids, has 4 C3H1-type Zinc finger, has 1 RING-type Zinc finger.

RING-type

E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins (By similarity), Inhibits neurogenesis and axis formation during embryonic development by modulating the phosphatidylinositol 3-kinase (PI3K) pathway (By similarity), Acts downstream of PI3K and akt1 to up-regulate gsk3b mRNA expression (By similarity)


This is ADP-ribosylation factor GTPase-activating protein 1 protein, from Mouse, contains 414 amino acids, has 1 C4-type Zinc finger.

GTPase-activating protein (GAP) for the ADP ribosylation factor 1 (ARF1), Involved in membrane trafficking and /or vesicle transport, Promotes hydrolysis of the ARF1-bound GTP and thus, is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles, a prerequisite for vesicle's fusion with target compartment, Probably regulates ARF1-mediated transport via its interaction with the KDELR proteins and TMED2, Overexpression induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, as when ARF1 is deactivated, Its activity is stimulated by phosphoinosides and inhibited by phosphatidylcholine (By similarity)


This is Zinc finger protein 354C protein, from Rat, contains 560 amino acids, has 11 C2H2-type Zinc finger.

May function as a transcription repressor, Binds to 5'-CCACA-3' core sequence, Suppresses osteogenic effects of RUNX2, May be involved in osteoblastic differentiation, Plays a role in postnatal myogenesis, may be involved in the regulation of satellite cells self-renewal (By similarity)


This is CXXC-type zinc finger protein 4 protein, from Rat, contains 198 amino acids, has 1 CXXC-type Zinc finger.

CXXC-type

Acts as a negative regulator of the Wnt signaling pathway via its interaction with DVL1 (By similarity), Binds preferentially to DNA containing cytidine-phosphate-guanosine (CpG) dinucleotides over CpH (H=A, T, and C), hemimethylated-CpG and hemimethylated-hydroxymethyl-CpG (By similarity)


This is Receptor-transporting protein 4 protein, from Mouse, contains 249 amino acids, has 1 3CxxC-type Zinc finger.

Probable chaperone protein which facilitates trafficking and functional cell surface expression of some G-protein coupled receptors (GPCRs), Promotes functional expression of the bitter taste receptor TAS2R16 (By similarity), Also promotes functional expression of the opioid receptor heterodimer OPRD1-OPRM1 (PubMed:18836069)


This is Intercellular adhesion molecule 4 protein, from Mouse, contains 262 amino acids, has 2 Ig-like C2-type Immunoglobulin domain.

Ig-like C2-type

Ig-like C2-type

Adhesion molecule that binds to leukocyte adhesion LFA-1 protein LFA-1 (integrin alpha-L/beta-2), ICAM4 is also a ligand for alpha-4/beta-1 and alpha-V integrins (By similarity), Isoform 2 may modulate binding of membrane-associated ICAM4

Belongs to the immunoglobulin superfamily, ICAM family


This is X-linked interleukin-1 receptor accessory protein-like 2 protein, from Mouse, contains 686 amino acids, has 3 Ig-like C2-type Immunoglobulin domain.

Ig-like C2-type

Ig-like C2-type

Ig-like C2-type

Belongs to the interleukin-1 receptor family


This is Zinc finger protein 22 protein, from Rat, contains 237 amino acids, has 5 C2H2-type Zinc finger.

Binds DNA through the consensus sequence 5'-CAATG-3', May be involved in transcriptional regulation and may play a role in tooth formation (By similarity)


This is Zinc finger protein 22 protein, from Mouse, contains 237 amino acids, has 5 C2H2-type Zinc finger.

Binds DNA through the consensus sequence 5'-CAATG-3', May be involved in transcriptional regulation and may play a role in tooth formation


This is Basal cell adhesion molecule protein, from Rat, contains 624 amino acids, has 2 Ig-like V-type Immunoglobulin domain, has 3 Ig-like C2-type Immunoglobulin domain.

Ig-like V-type

Ig-like V-type

Ig-like C2-type

Ig-like C2-type

Ig-like C2-type

Laminin alpha-5 receptor, May mediate intracellular signaling (By similarity)


This is Zinc finger CCHC domain-containing protein 17 protein, from Mouse, contains 241 amino acids, has 1 CCHC-type Zinc finger.

CCHC-type


This is Leucine-rich repeat neuronal protein 3 protein, from Rat, contains 707 amino acids, has 1 Ig-like C2-type Immunoglobulin domain.

Ig-like C2-type


This is PHD finger protein ALFIN-LIKE 1 protein, from Mouse-ear cress, contains 241 amino acids, has 1 PHD-type Zinc finger.

PHD-type

Histone-binding component that specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes


This is Probable E3 ubiquitin-protein ligase ARI13 protein, from Mouse-ear cress, contains 536 amino acids, has 1 RING-type Zinc finger, has 1 IBR-type Zinc finger, has 1 RING-type 2; atypical Zinc finger, has 1 RanBP2-type Zinc finger.

RING-type

IBR-type

RING-type 2; atypical

Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates


This is Zinc finger protein KNUCKLES protein, from Mouse-ear cress, contains 161 amino acids, has 1 C2H2-type Zinc finger.

May function as a transcriptional repressor of cellular proliferation that regulates floral determinacy and relative size of basal pattern elements along the proximo-distal axis of the developing gynoecium


This is Zinc finger protein GIS2 protein, from Mouse-ear cress, contains 191 amino acids, has 1 C2H2-type Zinc finger.

Probable transcription factor required for the initiation of inflorescence trichomes in response to gibberellin and cytokinin, Is not involved in the regulation of trichome branching, Is functionally equivalent to ZFP8


This is Protein LATE FLOWERING protein, from Mouse-ear cress, contains 173 amino acids, has 1 C2H2-type Zinc finger.

Acts as a transcriptional repressor, Prevents the photoperiodic and circadian clock-dependent transition to flowering in long days (LD) by repressing the expression of flowering time genes (e,g, FT, GI and CO) in the leaf vasculature, and by interfering with floral meristem identity genes at the apex (e,g, SOC1 and LFY)


This is Zinc-finger homeodomain protein 12 protein, from Mouse-ear cress, contains 223 amino acids, has 1 ZF-HD dimerization-type; degenerate Zinc finger.

ZF-HD dimerization-type; degenerate


This is Ubiquitin carboxyl-terminal hydrolase 17 protein, from Mouse-ear cress, contains 731 amino acids, has 1 MYND-type Zinc finger.

MYND-type

Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin, Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins (By similarity)


This is RING-H2 finger protein ATL73 protein, from Mouse-ear cress, contains 176 amino acids, has 1 RING-type; atypical Zinc finger.

RING-type; atypical

Belongs to the RING-type zinc finger family, ATL subfamily


This is Replication protein A 70 kDa DNA-binding subunit D protein, from Mouse-ear cress, contains 629 amino acids, has 1 C4-type Zinc finger.

Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication, The activity of RPA is mediated by single-stranded DNA binding and protein interactions, Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses (By similarity)

Belongs to the replication factor A protein 1 family


This is Zinc-finger homeodomain protein 13 protein, from Mouse-ear cress, contains 242 amino acids, has 1 ZF-HD dimerization-type; degenerate Zinc finger.

ZF-HD dimerization-type; degenerate


This is E3 ubiquitin-protein ligase ORTHRUS 3 protein, from Mouse-ear cress, contains 660 amino acids, has 1 PHD-type Zinc finger, has 2 RING-type Zinc finger.

PHD-type

RING-type

RING-type

E3 ubiquitin-protein ligase, May participate in CpG methylation-dependent transcriptional regulation (By similarity)


This is Zinc finger CCCH domain-containing protein 16 protein, from Mouse-ear cress, contains 435 amino acids, has 1 C3H1-type Zinc finger.


This is Leukocyte surface antigen CD47 protein, from Pig, contains 303 amino acids, has 1 Ig-like V-type Immunoglobulin domain.

Ig-like V-type

Adhesive protein that mediates cell-to-cell interactions (PubMed:12153520), Acts as receptor for thrombospondin THBS1 and as modulator of integrin signaling through the activation of heterotrimeric G proteins (PubMed:12153520), Involved in signal transduction, cardiovascular homeostasis, inflammation, apoptosis, angiogenesis, cellular self-renewal, and immunoregulation (By similarity), Plays a role in modulating pulmonary endothelin EDN1 signaling (By similarity), Modulates nitrous oxide (NO) signaling, in response to THBS1, hence playing a role as a pressor agent, supporting blood pressure (By similarity), Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity), Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells, Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation (By similarity), Positively modulates FAS-dependent apoptosis in T-cells, perhaps by enhancing FAS clustering (By similarity), Plays a role in suppressing angiogenesis and may be involved in metabolic dysregulation during normal aging (By similarity), In response to THBS1, negatively modulates wound healing, Inhibits stem cell self-renewal, in response to THBS1, probably by regulation of the stem cell transcription factors POU5F1/OCT4, SOX2, MYC/c-Myc and KLF4 (By similarity), May play a role in membrane transport and/or integrin dependent signal transduction (By similarity), May prevent premature elimination of red blood cells (By similarity)


This is Steroidogenic factor 1 protein, from Horse, contains 461 amino acids, has 2 NR C4-type Zinc finger.

NR C4-type

NR C4-type

Transcriptional activator, Seems to be essential for sexual differentiation and formation of the primary steroidogenic tissues, Binds to the Ad4 site found in the promoter region of steroidogenic P450 genes such as CYP11A, CYP11B and CYP21B, Also regulates the AMH/Muellerian inhibiting substance gene as well as the AHCH and STAR genes, 5'-YCAAGGYC-3' and 5'-RRAGGTCA-3' are the consensus sequences for the recognition by NR5A1, The SFPQ-NONO-NR5A1 complex binds to the CYP17 promoter and regulates basal and cAMP-dependent transcriptional activity, Binds phospholipids with a phosphatidylinositol (PI) headgroup, in particular PI(3,4)P2 and PI(3,4,5)P3, Activated by the phosphorylation of NR5A1 by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation (By similarity)

Belongs to the nuclear hormone receptor family, NR5 subfamily


This is Zinc finger MYND domain-containing protein 15 protein, from Human, contains 742 amino acids, has 1 MYND-type Zinc finger.

MYND-type

Acts as a transcriptional repressor through interaction with histone deacetylases (HDACs), May be important for spermiogenesis


This is DNA transposase THAP9 protein, from Human, contains 903 amino acids, has 1 THAP-type Zinc finger.

THAP-type

Active transposase that specifically recognizes the bipartite 5'-TXXGGGX(A/T)-3' consensus motif and mediates transposition


This is Zinc finger protein 576 protein, from Human, contains 170 amino acids, has 4 C2H2-type Zinc finger.

May be involved in transcriptional regulation

Belongs to the krueppel C2H2-type zinc-finger protein family


This is Zinc finger protein 442 protein, from Human, contains 627 amino acids, has 1 C2H2-type 1; degenerate Zinc finger, has 14 C2H2-type Zinc finger, has 1 C2H2-type 11; atypical Zinc finger.

C2H2-type 1; degenerate

C2H2-type 11; atypical


This is Zinc finger matrin-type protein 4 protein, from Human, contains 229 amino acids, has 4 Matrin-type Zinc finger.

Matrin-type

Matrin-type

Matrin-type

Matrin-type


This is E3 ubiquitin ligase RNF121 protein, from Human, contains 327 amino acids, has 1 RING-type; atypical Zinc finger.

RING-type; atypical

E3 ubiquitin ligase which accepts ubiquitin and transfers it to substrates thereby promoting their degradation by the endoplasmic reticulum-associated degradation (ERAD) pathway which is a pathway involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins (By similarity), May regulate the unfolded protein response to reduce endoplasmic reticulum stress (By similarity)


This is Zinc finger protein 160 protein, from Human, contains 818 amino acids, has 20 C2H2-type Zinc finger.


This is Endogenous retrovirus group K member 5 Gag polyprotein protein, from Human, contains 667 amino acids, has 2 CCHC-type Zinc finger.

CCHC-type

CCHC-type

The products of the Gag polyproteins of infectious retroviruses perform highly complex orchestrated tasks during the assembly, budding, maturation, and infection stages of the viral replication cycle, During viral assembly, the proteins form membrane associations and self-associations that ultimately result in budding of an immature virion from the infected cell, Gag precursors also function during viral assembly to selectively bind and package two plus strands of genomic RNA, Endogenous Gag proteins may have kept, lost or modified their original function during evolution

Belongs to the beta type-B retroviral Gag protein family, HERV class-II K(HML-2) gag subfamily


This is Putative E3 ubiquitin-protein ligase C36B7.05c protein, from Fission yeast, contains 279 amino acids, has 1 FYVE-type Zinc finger, has 1 RING-type; atypical Zinc finger.

FYVE-type

RING-type; atypical

Functions as an E3 ubiquitin-protein ligase, Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate


This is DNA topoisomerase 1 protein, from Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165), contains 770 amino acids, has 3 C4-type Zinc finger.

Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex, Introduces a single-strand break via transesterification at a target site in duplex DNA, The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand, The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils, Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1), contains 290 amino acids, has 1 C4-type Zinc finger.

Component of the acetyl coenzyme A carboxylase (ACC) complex, Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA


This is DNA topoisomerase 1 protein, from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1), contains 868 amino acids, has 3 C4-type Zinc finger.


This is Estrogen receptor beta-2 protein, from Goldfish, contains 610 amino acids, has 2 NR C4-type Zinc finger.

NR C4-type

NR C4-type

Binds estrogens with an affinity similar to that of ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner

Belongs to the nuclear hormone receptor family, NR3 subfamily


This is General transcription factor IIH subunit 2 protein, from Mouse, contains 396 amino acids, has 1 C4-type Zinc finger.

Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II, In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment, In transcription, TFIIH has an essential role in transcription initiation, When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape, Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription, The N-terminus of GTF2H2 interacts with and regulates XPD whereas an intact C-terminus is required for a successful escape of RNAP II form the promoter


This is Myotilin protein, from Mouse, contains 496 amino acids, has 2 Ig-like C2-type Immunoglobulin domain.

Ig-like C2-type

Ig-like C2-type

Component of a complex of multiple actin cross-linking proteins, Involved in the control of myofibril assembly and stability at the Z lines in muscle cells (By similarity)


This is AN1-type zinc finger protein 2A protein, from Mouse, contains 171 amino acids, has 2 AN1-type Zinc finger.


This is Natural killer cell receptor 2B4 protein, from Rat, contains 311 amino acids, has 2 Ig-like Immunoglobulin domain.

Ig-like

Ig-like

Modulate other receptor-ligand interactions to enhance leukocyte activation


This is Hypermethylated in cancer 2 protein protein, from Mouse, contains 619 amino acids, has 5 C2H2-type Zinc finger.

Belongs to the krueppel C2H2-type zinc-finger protein family, Hic subfamily


This is Insulinoma-associated protein 2 protein, from Mouse, contains 493 amino acids, has 1 C2H2-type 1; atypical Zinc finger, has 4 C2H2-type Zinc finger.

C2H2-type 1; atypical

May function as a growth suppressor or tumor suppressor in liver cells and in certain neurons


This is DnaJ homolog subfamily A member 4 protein, from Mouse, contains 397 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 1 protein, from Rat, contains 623 amino acids, has 1 Ig-like C2-type Immunoglobulin domain.

Ig-like C2-type


This is DNA topoisomerase 1 protein, from Mycoplasma gallisepticum, contains 719 amino acids, has 2 C4-type Zinc finger.

Belongs to the type IA topoisomerase family


This is DNA topoisomerase 1 protein, from Bacillus halodurans, contains 690 amino acids, has 3 C4-type Zinc finger.


This is DNA topoisomerase 1 protein, from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961), contains 876 amino acids, has 2 C4-type Zinc finger.


This is Formamidopyrimidine-DNA glycosylase protein, from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961), contains 269 amino acids, has 1 FPG-type Zinc finger.

FPG-type

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents, Acts as DNA glycosylase that recognizes and removes damaged bases, Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG), Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand, Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates


This is Formamidopyrimidine-DNA glycosylase protein, from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1), contains 270 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Type II restriction enzyme BslI subunit beta protein, from Bacillus sp. (strain NEB-606), contains 301 amino acids, has 1 CHC2-type Zinc finger.

A P subtype restriction enzyme that recognizes the double-stranded sequence 5'-CCN(7)GG-3' and cleaves after N-7


This is Probable BOI-related E3 ubiquitin-protein ligase 3 protein, from Mouse-ear cress, contains 335 amino acids, has 1 RING-type Zinc finger.

RING-type

Probable E3 ubiquitin-protein ligase, Has no effect on the stability of the DELLA proteins


This is Ubiquitin C-terminal hydrolase 22 protein, from Mouse-ear cress, contains 557 amino acids, has 1 UBP-type; degenerate Zinc finger.

UBP-type; degenerate

Component of a deubiquitination module (DUB module) that specifically deubiquinates monoubiquinated histone H2B (H2Bub) (PubMed:29588169, PubMed:30192741), Does not seem to be a component of the TREX-2 complex (PubMed:29588169), Seems to act independently of the SAGA multiprotein complex (PubMed:30192741), The DUB module is responsible for the major H2Bub deubiquitinase activity in Arabidopsis (PubMed:30192741)


This is E3 ubiquitin-protein ligase HAKAI homolog protein, from Mouse-ear cress, contains 360 amino acids, has 1 RING-type Zinc finger, has 1 C2H2-type Zinc finger.

RING-type

Probable E3 ubiquitin-protein ligase which is a subunit of the N6-methyltransferase complex, a multiprotein complex that mediates N6-methyladenosine (m6A) methylation at the 5'-[AG]GAC-3' consensus sites of some mRNAs (PubMed:28503769), Associates with MTA, MTB, FIP37 and VIR to form the m6A writer complex which is essential for adenosine methylation at specific mRNA sequences (PubMed:28503769), N6-methyladenosine (m6A) plays a role in mRNA stability, processing, translation efficiency and editing (PubMed:28503769)


This is Probable E3 ubiquitin-protein ligase LUL2 protein, from Mouse-ear cress, contains 299 amino acids, has 1 RING-type; atypical Zinc finger.

RING-type; atypical

Acts as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates (in vitro)

Belongs to the RING-type zinc finger family, LOG2 subfamily


This is Probable transcriptional regulator RABBIT EARS protein, from Mouse-ear cress, contains 226 amino acids, has 1 C2H2-type Zinc finger.

Probable transcriptional regulator essential for petal development, Required for the early development of the organ primordia of the second whorl, Acts downstream of AP1 and PTL


This is Plant-specific TFIIB-related protein 2 protein, from Mouse-ear cress, contains 336 amino acids, has 1 TFIIB-type Zinc finger.

TFIIB-type

Plant-specific TFIIB-related protein involved in the regulation of endosperm proliferation during the syncytial phase of endosperm development, Does not contribute to RNA polymerase IV or V activities in reproductive tissues


This is Zinc finger protein CONSTANS-LIKE 12 protein, from Mouse-ear cress, contains 364 amino acids, has 1 B box-type 1; atypical Zinc finger, has 1 B box-type 2; degenerate Zinc finger.

B box-type 1; atypical

B box-type 2; degenerate


This is Mini zinc finger protein 2 protein, from Mouse-ear cress, contains 100 amino acids, has 1 ZF-HD dimerization-type; degenerate Zinc finger.

ZF-HD dimerization-type; degenerate

Inhibits zinc finger homeodomain (ZHD) transcription factors by interacting with them to prevent both their nuclear localization and their DNA-binding properties, Involved in integrating signals from multiple hormones by regulating the expression of specific genes


This is RING-H2 finger protein ATL80 protein, from Mouse-ear cress, contains 197 amino acids, has 1 RING-type; atypical Zinc finger.

RING-type; atypical

May be involved in the early steps of the plant defense signaling pathway


This is E3 ubiquitin-protein ligase At1g12760 protein, from Mouse-ear cress, contains 408 amino acids, has 1 RING-type; atypical Zinc finger.

RING-type; atypical

Mediates E2-dependent protein ubiquitination in vitro


This is B-box domain protein 31 protein, from Mouse-ear cress, contains 121 amino acids, has 1 B box-type; atypical Zinc finger.

B box-type; atypical

Developmental regulator acting by forming heterodimeric complexes, that sequester CO and CO-like (COL) proteins into non-functional complexes (PubMed:27015278), Involved in the CO-mediated long-day flowering-promotion pathway (PubMed:27015278), Engages CO and the transcriptional repressor TPL in a tripartite complex (By similarity), Involved in the CO-mediated long-day flowering-promotion pathway (PubMed:27015278)


This is Dof zinc finger protein DOF5.7 protein, from Mouse-ear cress, contains 316 amino acids, has 1 Dof-type Zinc finger.

Dof-type

Transcription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence


This is Putative E3 ubiquitin-protein ligase ARI4 protein, from Mouse-ear cress, contains 529 amino acids, has 1 RING-type Zinc finger, has 1 IBR-type Zinc finger, has 1 RING-type 2; atypical Zinc finger.

RING-type

IBR-type

RING-type 2; atypical

Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates


This is Probable E3 ubiquitin-protein ligase ARI3 protein, from Mouse-ear cress, contains 537 amino acids, has 1 RING-type Zinc finger, has 1 IBR-type Zinc finger, has 1 RING-type 2; atypical Zinc finger.

RING-type

IBR-type

RING-type 2; atypical


This is ERAD-associated E3 ubiquitin-protein ligase HRD1A protein, from Mouse-ear cress, contains 492 amino acids, has 1 RING-type; atypical Zinc finger.

RING-type; atypical

Probable component of the HRD1 ubiquitin ligase complex that mediates the rapid degradation of misfolded endoplasmic reticulum (ER) proteins, a process called ER-associated degradation (ERAD), Targets the misfolded LRR receptor kinase BRI1, Functions redundantly with HRD3B


This is E3 ubiquitin-protein ligase ATL4 protein, from Mouse-ear cress, contains 334 amino acids, has 1 RING-type; atypical Zinc finger.

RING-type; atypical

E3 ubiquitin-protein ligase able to catalyze polyubiquitination with ubiquitin-conjugating enzyme E2 UBC8 in vitro


This is Methyl-CpG-binding domain-containing protein 4 protein, from Mouse-ear cress, contains 186 amino acids, has 1 CW-type Zinc finger.

CW-type

Transcriptional regulator that binds CpG, CpNpN and CpNpG (N is A, T, or C) islands in promoters regardless the DNA methylation status, Plays probably a role in gene silencing


This is Nuclear intron maturase 3, mitochondrial protein, from Mouse-ear cress, contains 723 amino acids, has 1 THAP-type Zinc finger.

THAP-type

Nuclear-encoded maturase required for splicing of group-II introns in mitochondria, Necessary for mitochondrial biogenesis during early developmental stages

Belongs to the plant nuclear intron maturase (nMat) family


This is Transcription factor bHLH140 protein, from Mouse-ear cress, contains 912 amino acids, has 1 C2H2-type Zinc finger.


This is Small ribosomal subunit protein eS27y protein, from Mouse-ear cress, contains 86 amino acids, has 1 C4-type Zinc finger.

May be involved in the elimination of damaged mRNA after UV irradiation

Belongs to the eukaryotic ribosomal protein eS27 family


This is Squamosa promoter-binding-like protein 15 protein, from Mouse-ear cress, contains 354 amino acids, has 1 SBP-type Zinc finger.

SBP-type

Trans-acting factor that binds specifically to the consensus nucleotide sequence 5'-TNCGTACAA-3'


This is Dof zinc finger protein DOF3.6 protein, from Mouse-ear cress, contains 323 amino acids, has 1 Dof-type Zinc finger.

Dof-type

Transcription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence, Enhances the DNA binding of OBF transcription factors to OCS elements


This is Anaphase-promoting complex subunit 11 protein, from Mouse-ear cress, contains 84 amino acids, has 1 RING-type; atypical Zinc finger.

RING-type; atypical

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle, The APC/C complex controls several key steps in the cell cycle by mediating ubiquitination and subsequent degradation of target proteins such as cyclins, The APC/C complex is required for the female gametophyte development and is involved in several aspect of development by controlling cell division and cell elongation, Involved in the control of endoreduplication, May recruit the E2 ubiquitin-conjugating enzymes to the complex (By similarity)


This is Cytotoxic T-lymphocyte protein 4 protein, from Pig, contains 223 amino acids, has 1 Ig-like V-type Immunoglobulin domain.

Ig-like V-type

Inhibitory receptor acting as a major negative regulator of T-cell responses, The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28


This is Mineralocorticoid receptor protein, from Common squirrel monkey, contains 982 amino acids, has 2 NR C4-type Zinc finger.

NR C4-type

NR C4-type

Receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol, Binds to mineralocorticoid response elements (MRE) and transactivates target genes, The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels (By similarity)


This is B-cell receptor CD22 protein, from Bornean orangutan, contains 330 amino acids, has 1 Ig-like V-type Immunoglobulin domain, has 2 Ig-like C2-type Immunoglobulin domain.

Ig-like V-type

Ig-like C2-type

Ig-like C2-type

Mediates B-cell B-cell interactions, May be involved in the localization of B-cells in lymphoid tissues, Binds sialylated glycoproteins; one of which is CD45, Preferentially binds to alpha-2,6-linked sialic acid (By similarity), Upon ligand-induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling, Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling cascade key molecules

Belongs to the immunoglobulin superfamily, SIGLEC (sialic acid binding Ig-like lectin) family


This is B-cell receptor CD22 protein, from Western lowland gorilla, contains 847 amino acids, has 1 Ig-like V-type Immunoglobulin domain, has 6 Ig-like C2-type Immunoglobulin domain.

Ig-like V-type

Ig-like C2-type

Ig-like C2-type

Ig-like C2-type

Ig-like C2-type

Ig-like C2-type

Ig-like C2-type


This is Low affinity immunoglobulin gamma Fc region receptor III-A protein, from Cat, contains 250 amino acids, has 2 Ig-like C2-type Immunoglobulin domain.

Ig-like C2-type

Ig-like C2-type

Receptor for the invariable Fc fragment of immunoglobulin gamma (IgG), Optimally activated upon binding of clustered antigen-IgG complexes displayed on cell surfaces, triggers lysis of antibody-coated cells, a process known as antibody-dependent cellular cytotoxicity (ADCC), Does not bind free monomeric IgG, thus avoiding inappropriate effector cell activation in the absence of antigenic trigger (By similarity), Mediates IgG effector functions on natural killer (NK) cells, Binds antigen-IgG complexes generated upon infection and triggers NK cell-dependent cytokine production and degranulation to limit viral load and propagation (By similarity), Fc-binding subunit that associates with FCER1G adapter to form functional signaling complexes, Following the engagement of antigen-IgG complexes, triggers phosphorylation of immunoreceptor tyrosine-based activation motif (ITAM)-containing adapter with subsequent activation of phosphatidylinositol 3-kinase signaling and sustained elevation of intracellular calcium that ultimately drive NK cell activation (By similarity), Mediates enhanced ADCC in response to afucosylated IgGs (PubMed:34485821)


This is Nuclear hormone receptor family member nhr-13 protein, from Caenorhabditis elegans, contains 425 amino acids, has 2 NR C4-type Zinc finger.

NR C4-type

NR C4-type

Orphan nuclear receptor (PubMed:22511885), Involved in regulating fatty acid desaturase genes, acting in concert with nuclear hormone receptor nhr-49 (PubMed:22511885)

Belongs to the nuclear hormone receptor family


This is Immunoglobulin domain-containing protein oig-1 protein, from Caenorhabditis elegans, contains 137 amino acids, has 1 Ig-like C2-type Immunoglobulin domain.

Ig-like C2-type

Plays a role in neural development, where it temporally regulates synapse formation in the D-type inhibitory GABAergic motor neurons, dorsal D (DD) and ventral D (VD) motor neurons (PubMed:26387713, PubMed:26083757), Controls the translocation of postsynaptic proteins, such as the acetylcholine receptor subunit acr-12, and presynaptic proteins, such as snb-1, along nerve cords to prevent premature synapse remodeling/formation (PubMed:26387713)


This is Centaurin-gamma-1A protein, from Fruit fly, contains 995 amino acids, has 1 C4-type Zinc finger.

GTPase-activating protein for the ADP ribosylation factor family

Belongs to the centaurin gamma-like family


This is Transcriptional repressor scratch 2 protein, from Human, contains 307 amino acids, has 4 C2H2-type Zinc finger, has 1 C2H2-type 5; atypical Zinc finger.

C2H2-type 5; atypical

May be involved in transcriptional regulation

Belongs to the snail C2H2-type zinc-finger protein family


This is Zinc finger protein 277 protein, from Human, contains 450 amino acids, has 2 C2H2-type Zinc finger.

Probable transcription factor, Involved in modulation of cellular senescence; represses transcription of the tumor suppressor gene INK4A/ARF, perhaps acting via the Polycomb group (PcG) complex PRC1


This is Semaphorin-3G protein, from Human, contains 782 amino acids, has 1 Ig-like C2-type Immunoglobulin domain.

Ig-like C2-type

Has chemorepulsive activities for sympathetic axons, Ligand of NRP2 (By similarity)


This is Immunoglobulin superfamily member 5 protein, from Human, contains 407 amino acids, has 2 Ig-like V-type Immunoglobulin domain.

Ig-like V-type

Ig-like V-type

Provides, together with MAGI1, an adhesion machinery at tight junctions, which may regulate the permeability of kidney glomerulus and small intestinal epithelial cells, Mediates calcium-independent homophilic cell adhesion, In testis, it may function as a cell adhesion molecule rather than a tight-junction protein, It may participate in the adhesion between spermatogonia-spermatogonia, spermatogonia-Sertoli cells, and Sertoli cells-Sertoli cells (By similarity)

Belongs to the immunoglobulin superfamily


This is tRNA:m(4)X modification enzyme TRM13 homolog protein, from Human, contains 481 amino acids, has 1 CHHC U11-48K-type Zinc finger.

CHHC U11-48K-type

tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His)

Belongs to the methyltransferase TRM13 family


This is Zinc finger protein 701 protein, from Human, contains 531 amino acids, has 1 C2H2-type 1; degenerate Zinc finger, has 8 C2H2-type Zinc finger.

C2H2-type 1; degenerate


This is Leucine-rich repeat and fibronectin type III domain-containing protein 1 protein, from Human, contains 771 amino acids, has 1 Ig-like Immunoglobulin domain.

Ig-like

Promotes neurite outgrowth in hippocampal neurons, Involved in the regulation and maintenance of excitatory synapses, Induces the clustering of excitatory postsynaptic proteins, including DLG4, DLGAP1, GRIA1 and GRIN1 (By similarity)


This is Zinc finger protein 624 protein, from Human, contains 865 amino acids, has 20 C2H2-type Zinc finger, has 1 C2H2-type 4; degenerate Zinc finger.

C2H2-type 4; degenerate


This is Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 1 protein, from Human, contains 623 amino acids, has 1 Ig-like C2-type Immunoglobulin domain.

Ig-like C2-type


This is THAP domain-containing protein 10 protein, from Human, contains 257 amino acids, has 1 THAP-type Zinc finger.

THAP-type


This is Pre-mRNA-splicing factor cwf24 protein, from Fission yeast, contains 533 amino acids, has 1 C3H1-type Zinc finger, has 1 RING-type Zinc finger.

RING-type


This is U1 small nuclear ribonucleoprotein C protein, from Fission yeast, contains 182 amino acids, has 1 Matrin-type Zinc finger.

Matrin-type

Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome, usp103/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing, The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA, Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region

Belongs to the U1 small nuclear ribonucleoprotein C family


This is Protein air1 protein, from Fission yeast, contains 315 amino acids, has 3 CCHC-type Zinc finger.

CCHC-type

CCHC-type

CCHC-type

Component of the TRAMP (TRF4) and TRAMP5 complexes which have a poly(A) RNA polymerase activity and are involved in a post-transcriptional quality control mechanism limiting inappropriate expression of genetic information, Polyadenylation is required for the degradative activity of the exosome on several of its nuclear RNA substrates like cryptic transcripts generated by RNA polymerase II and III, or hypomethylated pre-tRNAi-Met, Both complexes polyadenylate RNA processing and degradation intermediates of snRNAs, snoRNAs and mRNAs that accumulate in strains lacking a functional exosome


This is Pre-mRNA-splicing factor sap62 protein, from Fission yeast, contains 217 amino acids, has 1 Matrin-type Zinc finger.

Matrin-type

Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome


This is Probable ubiquitin carboxyl-terminal hydrolase 7 protein, from Fission yeast, contains 875 amino acids, has 1 UBP-type Zinc finger.

UBP-type


This is DNA topoisomerase 1 protein, from Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168), contains 700 amino acids, has 3 C4-type Zinc finger.

Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex, Introduces a single-strand break via transesterification at a target site in duplex DNA, The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand, The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils, Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone


This is Estrogen receptor beta protein, from Chicken, contains 472 amino acids, has 2 NR C4-type Zinc finger.

NR C4-type

NR C4-type

Binds estrogens with an affinity similar to that of ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner


This is Nuclear receptor subfamily 6 group A member 1-A protein, from Zebrafish, contains 477 amino acids, has 2 NR C4-type Zinc finger.

NR C4-type

NR C4-type

Probable orphan nuclear receptor, Binds to a response element containing repeats of the motif 5'-AGGTCA-3' (By similarity)

Belongs to the nuclear hormone receptor family, NR6 subfamily


This is Estrogen receptor beta protein, from Starling, contains 554 amino acids, has 2 NR C4-type Zinc finger.

NR C4-type

NR C4-type

Binds estrogens with an affinity similar to that of ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner, Locally synthesized estrogens may act via ER beta, in addition to ER alpha, to mediate seasonal or developmental effects on nearby song nuclei


This is Estrogen receptor protein, from Gilthead sea bream, contains 581 amino acids, has 2 NR C4-type Zinc finger.

NR C4-type

NR C4-type

The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues


This is E3 ubiquitin-protein ligase LAP protein, from RFV, contains 201 amino acids, has 1 RING-CH-type Zinc finger.

RING-CH-type

E3 ubiquitin-protein ligase which promotes ubiquitination and subsequent degradation of host MHC-I and CD4 molecules, presumably to prevent lysis of infected cells by cytotoxic T-lymphocytes and NK cell, Binds target molecules through transmembrane interaction, The result of this ubiquitination is the enhancement of the endocytosis of the target chain and the delivery to the lysosome, where it is proteolytically destroyed

Belongs to the poxviridae LAP protein family


This is Endogenous retrovirus group K member 18 Pol protein protein, from Human, contains 812 amino acids, has 1 Integrase-type Zinc finger.

Integrase-type

Early post-infection, the reverse transcriptase converts the viral RNA genome into double-stranded viral DNA, The RNase H domain of the reverse transcriptase performs two functions, It degrades the RNA template and specifically removes the RNA primer from the RNA/DNA hybrid, Following nuclear import, the integrase catalyzes the insertion of the linear, double-stranded viral DNA into the host cell chromosome, Endogenous Pol proteins may have kept, lost or modified their original function during evolution

Belongs to the beta type-B retroviral polymerase family, HERV class-II K(HML-2) pol subfamily


This is Hyaluronan and proteoglycan link protein 1 protein, from Mouse, contains 356 amino acids, has 1 Ig-like V-type Immunoglobulin domain.

Ig-like V-type

Stabilizes the aggregates of proteoglycan monomers with hyaluronic acid in the extracellular cartilage matrix


This is Tripartite motif-containing protein 44 protein, from Mouse, contains 346 amino acids, has 1 B box-type Zinc finger.

B box-type

May play a role in the process of differentiation and maturation of neuronal cells (By similarity), May regulate the activity of TRIM17 (By similarity), Is a negative regulator of PAX6 expression (By similarity)


This is Zinc finger protein 354B protein, from Mouse, contains 601 amino acids, has 13 C2H2-type Zinc finger.

May be involved in transcriptional regulation

Belongs to the krueppel C2H2-type zinc-finger protein family


This is DnaJ homolog subfamily A member 2 protein, from Mouse, contains 412 amino acids, has 1 CR-type Zinc finger.

CR-type

Co-chaperone of Hsc70, Stimulates ATP hydrolysis and the folding of unfolded proteins mediated by HSPA1A/B (in vitro)


This is Zinc finger Ran-binding domain-containing protein 2 protein, from Mouse, contains 330 amino acids, has 2 RanBP2-type Zinc finger.

Splice factor required for alternative splicing of TRA2B/SFRS10 transcripts, May interfere with constitutive 5'-splice site selection (By similarity)


This is Basal cell adhesion molecule protein, from Mouse, contains 622 amino acids, has 2 Ig-like V-type Immunoglobulin domain, has 3 Ig-like C2-type Immunoglobulin domain.

Ig-like V-type

Ig-like V-type

Ig-like C2-type

Ig-like C2-type

Ig-like C2-type

Laminin alpha-5 receptor, May mediate intracellular signaling (By similarity)


This is E3 ubiquitin-protein ligase RNF103 protein, from Mouse, contains 683 amino acids, has 1 RING-type Zinc finger.

RING-type

Acts as an E2-dependent E3 ubiquitin-protein ligase, probably involved in the ER-associated protein degradation pathway


This is DNA repair protein RadA protein, from Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / CCUG 27074 / LMG 4051 / NBRC 15346 / NCIMB 9279 / VKM B-1422 / R1), contains 503 amino acids, has 1 C4-type Zinc finger.

Plays a role in DNA damage repair (Ref,2), Following severe irradiation (IR, 7 kGy of gamma irradiation), genomic DNA is fragmented and progressively degraded for the first 1,5 hours after IR, in a step promoted by RecA and counterbalanced by DNA Pol I and Pol III, This is followed by massive DNA synthesis and genome reassembly in the next hour, Optimal priming of DNA synthesis requires both RecA and RadA, Pol III initiates DNA synthesis while both Pol I and Pol III are required for its continuation (PubMed:19303848)

Belongs to the RecA family, RadA subfamily


This is Formamidopyrimidine-DNA glycosylase protein, from Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / CCUG 27074 / LMG 4051 / NBRC 15346 / NCIMB 9279 / VKM B-1422 / R1), contains 280 amino acids, has 1 FPG-type Zinc finger.

FPG-type

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents, Acts as DNA glycosylase that recognizes and removes damaged bases, Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG), Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand, Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)


This is Squamosa promoter-binding-like protein 5 protein, from Mouse-ear cress, contains 181 amino acids, has 1 SBP-type Zinc finger.

SBP-type

Trans-acting factor that binds specifically to the consensus nucleotide sequence 5'-TNCGTACAA-3' of AP1 promoter, Promotes both vegetative phase change and flowering


This is Squamosa promoter-binding-like protein 4 protein, from Mouse-ear cress, contains 174 amino acids, has 1 SBP-type Zinc finger.

SBP-type


This is Squamosa promoter-binding-like protein 2 protein, from Mouse-ear cress, contains 419 amino acids, has 1 SBP-type Zinc finger.

SBP-type

Trans-acting factor that binds specifically to the consensus nucleotide sequence 5'-TNCGTACAA-3'


This is Replication protein A 70 kDa DNA-binding subunit B protein, from Mouse-ear cress, contains 604 amino acids, has 1 C4-type Zinc finger.

Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication, The activity of RPA is mediated by single-stranded DNA binding and protein interactions (By similarity), Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses (By similarity)

Belongs to the replication factor A protein 1 family


This is Cyclic dof factor 5 protein, from Mouse-ear cress, contains 399 amino acids, has 1 Dof-type Zinc finger.

Dof-type

Transcription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence (By similarity), Regulates a photoperiodic flowering response, Transcriptional repressor of 'CONSTANS' expression


This is Zinc finger protein ZAT2 protein, from Mouse-ear cress, contains 270 amino acids, has 3 C2H2-type Zinc finger.

Mediates the regulation of male germ cell division by DUO1


This is Ubiquitin carboxyl-terminal hydrolase 19 protein, from Mouse-ear cress, contains 672 amino acids, has 1 MYND-type Zinc finger.

MYND-type

Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin, Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins (By similarity)


This is Serine/arginine-rich splicing factor RSZ22A protein, from Mouse-ear cress, contains 196 amino acids, has 1 CCHC-type Zinc finger.

CCHC-type

Probably involved in intron recognition and spliceosome assembly

Belongs to the splicing factor SR family, RSZ subfamily


This is Chaperone protein dnaJ A6, chloroplastic protein, from Mouse-ear cress, contains 442 amino acids, has 1 CR-type Zinc finger.

CR-type

May function together with HSC70 chaperone to assist protein folding and prevent protein aggregation during heat stress in the chloroplast


This is Zinc finger protein CONSTANS-LIKE 3 protein, from Mouse-ear cress, contains 294 amino acids, has 1 B box-type 1; atypical Zinc finger, has 1 B box-type 2; atypical Zinc finger.

B box-type 1; atypical

B box-type 2; atypical


This is E3 ubiquitin-protein ligase ATL15 protein, from Mouse-ear cress, contains 381 amino acids, has 1 RING-type; atypical Zinc finger.

RING-type; atypical

E3 ubiquitin-protein ligase able to catalyze polyubiquitination with ubiquitin-conjugating enzyme E2 UBC8, UBC10, UBC11, UBC28 and UBC29 in vitro

Belongs to the RING-type zinc finger family, ATL subfamily


This is Probable E3 ubiquitin-protein ligase ARI11 protein, from Mouse-ear cress, contains 542 amino acids, has 1 RING-type Zinc finger, has 1 IBR-type Zinc finger, has 1 RING-type 2; atypical Zinc finger.

RING-type

IBR-type

RING-type 2; atypical

Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates

Belongs to the RBR family, Ariadne subfamily


This is Probable E3 ubiquitin-protein ligase ARI9 protein, from Mouse-ear cress, contains 543 amino acids, has 1 RING-type Zinc finger, has 1 IBR-type Zinc finger, has 1 RING-type 2; atypical Zinc finger.

RING-type

IBR-type

RING-type 2; atypical


This is Probable E3 ubiquitin-protein ligase ARI10 protein, from Mouse-ear cress, contains 514 amino acids, has 1 RING-type Zinc finger, has 1 IBR-type Zinc finger, has 1 RING-type 2; atypical Zinc finger.

RING-type

IBR-type

RING-type 2; atypical


This is FCS-Like Zinc finger 11 protein, from Mouse-ear cress, contains 324 amino acids, has 1 FLZ-type Zinc finger.

FLZ-type

May act as an adapter to facilitate the interaction of SnRK1 complex with effector proteins, conferring tissue- and stimulus-type specific differences in the SnRK1 regulation pathway


This is Methionine aminopeptidase 1A protein, from Mouse-ear cress, contains 398 amino acids, has 1 C6H2-type Zinc finger.

Cotranslationally removes the N-terminal methionine from nascent proteins, The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val)

Belongs to the peptidase M24A family, Methionine aminopeptidase type 1 subfamily


This is E3 ubiquitin-protein ligase ATL59 protein, from Mouse-ear cress, contains 225 amino acids, has 1 RING-type; atypical Zinc finger.

RING-type; atypical

E3 ubiquitin-protein ligase able to catalyze polyubiquitination with ubiquitin-conjugating enzyme E2 UBC8, UBC10, UBC11, and UBC34 in vitro


This is Transcriptional regulator TAC1 protein, from Mouse-ear cress, contains 172 amino acids, has 1 C2H2-type Zinc finger.

Activation factor which mediates telomerase activity and potentiates responses to auxin through the regulation of BT2, Binds in vitro to the DNA sequence 5'-GACAGTGTTAC-3' of the BT2 promoter


This is PHD finger protein ALFIN-LIKE 2 protein, from Mouse-ear cress, contains 246 amino acids, has 1 PHD-type Zinc finger.

PHD-type

Histone-binding component that specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes


This is Zinc finger protein AZF3 protein, from Mouse-ear cress, contains 193 amino acids, has 2 C2H2-type Zinc finger.

Transcriptional repressor probably involved in abiotic stress responses, Binds DNA in a sequence-specific manner and can repress the transactivation activity of other transcription factors


This is Zinc finger protein AZF1 protein, from Mouse-ear cress, contains 245 amino acids, has 2 C2H2-type Zinc finger.

Transcriptional repressor involved in the inhibition of plant growth under abiotic stress conditions, Can repress the expression of various genes, including osmotic stress and abscisic acid-repressive genes and auxin-inducible genes, by binding to their promoter regions in a DNA sequence-specific manner


This is Zinc finger A20 and AN1 domain-containing stress-associated protein 10 protein, from Mouse-ear cress, contains 130 amino acids, has 1 A20-type Zinc finger, has 1 AN1-type Zinc finger.

May be involved in environmental stress response


This is Dof zinc finger protein DOF4.2 protein, from Mouse-ear cress, contains 194 amino acids, has 1 Dof-type Zinc finger.

Dof-type

Transcription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence


This is E3 ubiquitin-protein ligase CSU1 protein, from Mouse-ear cress, contains 310 amino acids, has 1 RING-type 1; degenerate Zinc finger, has 1 RING-type Zinc finger.

RING-type 1; degenerate

RING-type

RING-finger E3 ubiquitin-protein ligase that plays an major role in maintaining COP1 homeostasis in darkness, Negatively regulates COP1 protein accumulation by targeting COP1 for ubiquitination and subsequent proteasomal degradation in dark-grown seedlings, Negatively regulates the accumulation of SPA1 protein in the dark


This is Protein FAR1-RELATED SEQUENCE 5 protein, from Mouse-ear cress, contains 788 amino acids, has 1 SWIM-type Zinc finger.

SWIM-type

Putative transcription activator involved in regulating light control of development


This is tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like protein, from Mouse-ear cress, contains 691 amino acids, has 2 C3H1-type Zinc finger.

Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs, Specifically modifies U47 in cytoplasmic tRNAs (By similarity), Catalyzes the synthesis of dihydrouridine in some mRNAs, thereby affecting their translation (By similarity)

Belongs to the Dus family, Dus3 subfamily


This is Photoreceptor-specific nuclear receptor protein, from Bovine, contains 411 amino acids, has 2 NR C4-type Zinc finger.

NR C4-type

NR C4-type

Orphan nuclear receptor of retinal photoreceptor cells, Transcriptional factor that is an activator of rod development and repressor of cone development, Binds the promoter region of a number of rod- and cone-specific genes, including rhodopsin, M- and S-opsin and rod-specific phosphodiesterase beta subunit, Enhances rhodopsin expression, Represses M- and S-cone opsin expression

Belongs to the nuclear hormone receptor family


This is COUP transcription factor 1 protein, from Bovine, contains 424 amino acids, has 2 NR C4-type Zinc finger.

NR C4-type

NR C4-type

Coup (chicken ovalbumin upstream promoter) transcription factor binds to the ovalbumin promoter and, in conjunction with another protein (S300-II) stimulates initiation of transcription, Binds to both direct repeats and palindromes of the 5'-AGGTCA-3' motif, Represses transcriptional activity of LHCG (By similarity)

Belongs to the nuclear hormone receptor family, NR2 subfamily


This is Estrogen receptor beta protein, from Sheep, contains 527 amino acids, has 2 NR C4-type Zinc finger.

NR C4-type

NR C4-type

Nuclear hormone receptor, Binds estrogens with an affinity similar to that of ESR1/ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner

Belongs to the nuclear hormone receptor family, NR3 subfamily


This is Nuclear hormone receptor family member nhr-91 protein, from Caenorhabditis elegans, contains 474 amino acids, has 2 NR C4-type Zinc finger.

NR C4-type

NR C4-type


This is Zip homologous protein 2 protein, from Caenorhabditis elegans, contains 240 amino acids, has 1 RING-type Zinc finger.

RING-type

Recruited co-dependently with zhp-1 to the synaptonemal complex between homologous chromosome pairs to regulate the formation and number of crossover events between homologs during meiotic recombination (PubMed:29521627), Together with zhp-1, promotes the accumulation of pro-crossover proteins, including zhp-3 and zhp-4, at a designated crossover site along the recombination intermediate (PubMed:29521627), Limits the number of crossover sites along a recombination intermediate by restricting the association of these pro-crossover proteins with other recombination sites during late prophase (PubMed:29521627), Also, together with zhp-1, plays a role in chromosome remodeling following crossover formation to promote two successive rounds of chromosome segregation during meiosis (PubMed:29521627)


This is Zinc finger protein 282 protein, from Human, contains 671 amino acids, has 5 C2H2-type Zinc finger.

Binds to the U5 repressive element (U5RE) of the human T cell leukemia virus type I long terminal repeat, It recognizes the 5'-TCCACCCC-3' sequence as a core motif and exerts a strong repressive effect on HTLV-I LTR-mediated expression


This is Zinc finger HIT domain-containing protein 2 protein, from Human, contains 403 amino acids, has 1 HIT-type Zinc finger.

HIT-type

May act as a bridging factor mediating the interaction between the R2TP/Prefoldin-like (R2TP/PFDL) complex and U5 small nuclear ribonucleoprotein (U5 snRNP) (PubMed:28561026), Required for the interaction of R2TP complex subunit RPAP3 and prefoldin-like subunit URI1 with U5 snRNP proteins EFTUD2 and PRPF8 (PubMed:28561026), May play a role in regulating the composition of the U5 snRNP complex (PubMed:28561026)


This is Zinc finger protein 112 protein, from Human, contains 913 amino acids, has 1 C2H2-type 1; degenerate Zinc finger, has 1 C2H2-type 2; degenerate Zinc finger, has 1 C2H2-type 3; degenerate Zinc finger, has 1 C2H2-type 4; degenerate Zinc finger, has 13 C2H2-type Zinc finger.

C2H2-type 1; degenerate

C2H2-type 2; degenerate

C2H2-type 3; degenerate

C2H2-type 4; degenerate

May be involved in transcriptional regulation


This is Zinc finger protein 229 protein, from Human, contains 825 amino acids, has 1 C2H2-type 1; degenerate Zinc finger, has 17 C2H2-type Zinc finger.

C2H2-type 1; degenerate


This is Zinc finger protein 223 protein, from Human, contains 482 amino acids, has 8 C2H2-type Zinc finger, has 1 C2H2-type 6; degenerate Zinc finger, has 1 C2H2-type 10; degenerate Zinc finger.

C2H2-type 6; degenerate

C2H2-type 10; degenerate


This is Zinc finger protein 221 protein, from Human, contains 617 amino acids, has 14 C2H2-type Zinc finger, has 1 C2H2-type 4; degenerate Zinc finger.

C2H2-type 4; degenerate