This is RAS guanyl-releasing protein 2-A protein, from African clawed frog, contains 594 amino acids, has 1 Phorbol-ester/DAG-type Zinc finger.

Phorbol-ester/DAG-type

Functions as a calcium- and DAG-regulated nucleotide exchange factor specifically activating Rap through the exchange of bound GDP for GTP, May function in cell aggregation and adhesion


This is MBT domain-containing protein 1 protein, from African clawed frog, contains 621 amino acids, has 1 FCS-type Zinc finger.

FCS-type

Chromatin reader component of the NuA4 histone acetyltransferase complex, a multiprotein complex involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A, The NuA4 complex plays a direct role in repair of DNA double-strand breaks (DSBs) by promoting homologous recombination (HR), MBTD1 specifically recognizes and binds monomethylated and dimethylated 'Lys-20' on histone H4 (H4K20me1 and H4K20me2, respectively), In the NuA4 complex, MBTD1 promotes recruitment of the complex to H4K20me marks by competing with TP53BP1 for binding to H4K20me, Following recruitment to H4K20me at DNA breaks, the NuA4 complex catalyzes acetylation of 'Lys-15' on histone H2A (H2AK15), blocking the ubiquitination mark required for TP53BP1 localization at DNA breaks, thereby promoting homologous recombination (HR)


This is Protein odd-skipped-related 2-A protein, from African clawed frog, contains 271 amino acids, has 3 C2H2-type Zinc finger.

Transcriptional repressor, Required for pronephric kidney development

Belongs to the Odd C2H2-type zinc-finger protein family


This is Immunoglobulin-like domain-containing receptor 1 protein, from African clawed frog, contains 545 amino acids, has 1 Ig-like V-type Immunoglobulin domain.

Ig-like V-type

Maintains epithelial barrier function by recruiting MARVELD2/tricellulin to tricellular tight junctions (tTJs)

Belongs to the immunoglobulin superfamily, LISCH7 family


This is E3 ubiquitin-protein ligase RNF10 protein, from African clawed frog, contains 756 amino acids, has 1 RING-type Zinc finger.

RING-type

E3 ubiquitin-protein ligase that catalyzes monoubiquitination of 40S ribosomal proteins RPS2/us5 and RPS3/us3 in response to ribosome stalling, Part of a ribosome quality control that takes place when ribosomes have stalled during translation initiation (iRQC): RNF10 acts by mediating monoubiquitination of RPS2/us5 and RPS3/us3, promoting their degradation by the proteasome


This is DNA-directed RNA polymerase II subunit RPB9 protein, from Bovine, contains 125 amino acids, has 1 C4-type Zinc finger, has 1 TFIIS-type Zinc finger.

TFIIS-type

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates, Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs, Pol II is the central component of the basal RNA polymerase II transcription machinery, It is composed of mobile elements that move relative to each other, RPB9 is part of the upper jaw surrounding the central large cleft and thought to grab the incoming DNA template (By similarity)

Belongs to the archaeal RpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family


This is U1 small nuclear ribonucleoprotein C protein, from Bovine, contains 159 amino acids, has 1 Matrin-type Zinc finger.

Matrin-type

Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome, SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing, The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA, Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region

Belongs to the U1 small nuclear ribonucleoprotein C family


This is Structure-specific endonuclease subunit SLX1 protein, from Bovine, contains 267 amino acids, has 1 SLX1-type Zinc finger.

Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination, Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA, Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs), Resolves HJs by generating two pairs of ligatable, nicked duplex products


This is Myelin protein zero-like protein 1 protein, from Bovine, contains 269 amino acids, has 1 Ig-like V-type Immunoglobulin domain.

Ig-like V-type

Cell surface receptor, which is involved in signal transduction processes, Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2, Is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases, May be involved in regulation of integrin-mediated cell motility (By similarity)


This is Cilium assembly protein DZIP1L protein, from Zebrafish, contains 756 amino acids, has 1 C2H2-type Zinc finger.

Involved in primary cilium formation (PubMed:28530676), Probably acts as a transition zone protein required for localization of PKD1/PC1 and PKD2/PC2 to the ciliary membrane

Cytoplasm, cytoskeleton, cilium basal body

Belongs to the DZIP C2H2-type zinc-finger protein family


This is Leucine-rich repeat neuronal protein 1 protein, from Rat, contains 716 amino acids, has 1 Ig-like C2-type Immunoglobulin domain.

Ig-like C2-type


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic protein, from Garden lettuce, contains 508 amino acids, has 1 C4-type Zinc finger.

Component of the acetyl coenzyme A carboxylase (ACC) complex, Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA


This is Probable E3 ubiquitin-protein ligase XBOS33 protein, from Rice, contains 520 amino acids, has 1 RING-type Zinc finger.

RING-type


This is Translational activator com protein, from Bacteriophage Mu, contains 62 amino acids, has 1 Atypical Zinc finger.

Atypical

Trans-acting positive regulator required for mom mRNA translation, Binds the com-mom mRNA 5' and destabilizes a translation inhibition stem to expose mom translation start signals


This is Squamosa promoter-binding protein 2 protein, from Garden snapdragon, contains 171 amino acids, has 1 SBP-type Zinc finger.

SBP-type

Probable transcriptional factor, Binds to the promoter of the SQUAMOSA gene


This is Squamosa promoter-binding protein 1 protein, from Garden snapdragon, contains 131 amino acids, has 1 SBP-type Zinc finger.

SBP-type


This is Formamidopyrimidine-DNA glycosylase protein, from Lactobacillus sakei subsp. sakei, contains 278 amino acids, has 1 FPG-type Zinc finger.

FPG-type

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents, Acts as DNA glycosylase that recognizes and removes damaged bases, Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG), Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand, Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates


This is Chaperone protein DnaJ protein, from Lactobacillus sakei subsp. sakei, contains 383 amino acids, has 1 CR-type Zinc finger.

CR-type

Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion, Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex, GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle, Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding, Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Lactobacillus sakei subsp. sakei, contains 283 amino acids, has 1 C4-type Zinc finger.


This is Formamidopyrimidine-DNA glycosylase protein, from Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383), contains 275 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Chaperone protein DnaJ protein, from Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383), contains 378 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Formamidopyrimidine-DNA glycosylase protein, from Geobacter metallireducens (strain ATCC 53774 / DSM 7210 / GS-15), contains 267 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Formamidopyrimidine-DNA glycosylase protein, from Pelobacter carbinolicus, contains 271 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Pelobacter carbinolicus, contains 282 amino acids, has 1 C4-type Zinc finger.


This is Chaperone protein DnaJ protein, from Pelobacter carbinolicus, contains 373 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Formamidopyrimidine-DNA glycosylase protein, from Carboxydothermus hydrogenoformans (strain ATCC BAA-161 / DSM 6008 / Z-2901), contains 263 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Carboxydothermus hydrogenoformans (strain ATCC BAA-161 / DSM 6008 / Z-2901), contains 280 amino acids, has 1 C4-type Zinc finger.


This is Chaperone protein DnaJ protein, from Carboxydothermus hydrogenoformans (strain ATCC BAA-161 / DSM 6008 / Z-2901), contains 381 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Synechococcus sp. (strain CC9605), contains 293 amino acids, has 1 C4-type Zinc finger.


This is Chaperone protein DnaJ protein, from Chlorobium chlorochromatii (strain CaD3), contains 400 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Chlorobium chlorochromatii (strain CaD3), contains 279 amino acids, has 1 C4-type Zinc finger.


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Synechococcus sp. (strain CC9902), contains 293 amino acids, has 1 C4-type Zinc finger.


This is Chaperone protein DnaJ protein, from Pelodictyon luteolum, contains 382 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Pelodictyon luteolum, contains 281 amino acids, has 1 C4-type Zinc finger.


This is Fc receptor-like A protein, from Rat, contains 347 amino acids, has 2 Ig-like C2-type Immunoglobulin domain.

Ig-like C2-type

Ig-like C2-type

May be implicated in B-cell differentiation and lymphomagenesis


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic protein, from Moth orchid, contains 497 amino acids, has 1 C4-type Zinc finger.


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Xanthomonas campestris pv. vesicatoria (strain 85-10), contains 295 amino acids, has 1 C4-type Zinc finger.


This is Chaperone protein DnaJ protein, from Xanthomonas campestris pv. vesicatoria (strain 85-10), contains 375 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Protein FAR1-RELATED SEQUENCE 12 protein, from Mouse-ear cress, contains 788 amino acids, has 1 SWIM-type Zinc finger.

SWIM-type

Putative transcription activator involved in regulating light control of development


This is DEAD-box ATP-dependent RNA helicase 41 protein, from Mouse-ear cress, contains 505 amino acids, has 1 HIT-type Zinc finger.

HIT-type

Belongs to the DEAD box helicase family, DDX59 subfamily


This is Protein FAR1-RELATED SEQUENCE 2 protein, from Mouse-ear cress, contains 807 amino acids, has 1 SWIM-type Zinc finger.

SWIM-type


This is Chaperone protein DnaJ protein, from Pseudoalteromonas translucida (strain TAC 125), contains 380 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Pseudoalteromonas translucida (strain TAC 125), contains 291 amino acids, has 1 C4-type Zinc finger.


This is Large ribosomal subunit protein eL42 protein, from Halobacterium pharaonis, contains 93 amino acids, has 1 C4-type Zinc finger.

Belongs to the eukaryotic ribosomal protein eL42 family


This is Chaperone protein DnaJ protein, from Halobacterium pharaonis, contains 380 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Formamidopyrimidine-DNA glycosylase protein, from Rhodobacter sphaeroides, contains 283 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Chaperone protein DnaJ protein, from Rhodobacter sphaeroides, contains 382 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Chaperone protein DnaJ protein, from Nitrosococcus oceani (strain ATCC 19707 / BCRC 17464 / JCM 30415 / NCIMB 11848 / C-107), contains 380 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Formamidopyrimidine-DNA glycosylase protein, from Nitrosococcus oceani (strain ATCC 19707 / BCRC 17464 / JCM 30415 / NCIMB 11848 / C-107), contains 271 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Chaperone protein DnaJ protein, from Burkholderia pseudomallei (strain 1710b), contains 376 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Formamidopyrimidine-DNA glycosylase protein, from Burkholderia pseudomallei (strain 1710b), contains 276 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Formamidopyrimidine-DNA glycosylase protein, from Streptococcus agalactiae serotype Ia (strain ATCC 27591 / A909 / CDC SS700), contains 273 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Chaperone protein DnaJ protein, from Streptococcus agalactiae serotype Ia (strain ATCC 27591 / A909 / CDC SS700), contains 371 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Formamidopyrimidine-DNA glycosylase protein, from Pseudomonas fluorescens (strain Pf0-1), contains 270 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Pseudomonas fluorescens (strain Pf0-1), contains 306 amino acids, has 1 C4-type Zinc finger.


This is Chaperone protein DnaJ protein, from Chlamydia trachomatis serovar A (strain ATCC VR-571B / DSM 19440 / HAR-13), contains 392 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Zinc finger protein SNAI3 protein, from Human, contains 292 amino acids, has 4 C2H2-type Zinc finger, has 1 C2H2-type 5; degenerate Zinc finger.

C2H2-type 5; degenerate

Seems to inhibit myoblast differentiation, Transcriptional repressor of E-box-dependent transactivation of downstream myogenic bHLHs genes, Binds preferentially to the canonical E-box sequences 5'-CAGGTG-3' and 5'-CACCTG-3' (By similarity)

Belongs to the snail C2H2-type zinc-finger protein family


This is Zinc finger protein 791 protein, from Human, contains 576 amino acids, has 17 C2H2-type Zinc finger.

May be involved in transcriptional regulation

Belongs to the krueppel C2H2-type zinc-finger protein family


This is E3 ubiquitin-protein ligase RNF166 protein, from African clawed frog, contains 241 amino acids, has 1 RING-type Zinc finger, has 1 C2HC RNF-type Zinc finger.

RING-type

C2HC RNF-type

E3 ubiquitin-protein ligase that promotes the ubiquitination of different substrates


This is Pre-mRNA-splicing factor SLU7 protein, from African clawed frog, contains 580 amino acids, has 1 CCHC-type Zinc finger.

CCHC-type

Required for pre-mRNA splicing as component of the spliceosome, Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron, Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region, May be involved in the activation of proximal AG, Probably also involved in alternative splicing regulation


This is Small t antigen protein, from SV-12, contains 172 amino acids, has 1 C4-type; atypical Zinc finger, has 1 H1C3-type; atypical Zinc finger.

C4-type; atypical

H1C3-type; atypical

Promotes efficient viral genome replication by accelerating both G1 and S phase progression of the cell cycle, Inhibits host PP2A by binding to the A subunit, thereby displacing lower affinity regulatory B subunit, Inactivation of PP2A in turn results in the transactivation of cyclin A and cyclin D1 promoters, Late during the infection cycle, ST may induce dephosphorylation of host MTOR, leading to the inhibition of cap-dependent translation, May establish and maintain high levels of viral genomes during persistent infection in cell culture


This is Formamidopyrimidine-DNA glycosylase protein, from Anabaena variabilis, contains 277 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Chaperone protein DnaJ protein, from Anabaena variabilis, contains 376 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Anabaena variabilis, contains 316 amino acids, has 1 C4-type Zinc finger.


This is T-cell surface protein tactile protein, from Bovine, contains 570 amino acids, has 2 Ig-like V-type Immunoglobulin domain, has 1 Ig-like C2-type Immunoglobulin domain.

Ig-like V-type

Ig-like V-type

Ig-like C2-type

May be involved in adhesive interactions of activated T and NK cells during the late phase of the immune response, Promotes NK cell-target adhesion by interacting with PVR present on target cells, May function at a time after T and NK cells have penetrated the endothelium using integrins and selectins, when they are actively engaging diseased cells and moving within areas of inflammation (By similarity)


This is ADP-ribosylation factor GTPase-activating protein 2 protein, from Rat, contains 520 amino acids, has 1 C4-type Zinc finger.

GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1), May regulate coatomer-mediated protein transport from the Golgi complex to the endoplasmic reticulum, Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes (By similarity)


This is Zinc finger protein 528 protein, from Human, contains 628 amino acids, has 15 C2H2-type Zinc finger.


This is Chaperone protein DnaJ protein, from Thiobacillus denitrificans (strain ATCC 25259), contains 372 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Formamidopyrimidine-DNA glycosylase protein, from Thiobacillus denitrificans (strain ATCC 25259), contains 270 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Formamidopyrimidine-DNA glycosylase protein, from Nitrobacter winogradskyi (strain ATCC 25391 / DSM 10237 / CIP 104748 / NCIMB 11846 / Nb-255), contains 293 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Zinc finger-containing ubiquitin peptidase 1 protein, from Bovine, contains 579 amino acids, has 3 C2H2-type Zinc finger, has 1 C2H2-type 2; atypical Zinc finger.

C2H2-type 2; atypical

Deubiquitinase with endodeubiquitinase activity that specifically interacts with and cleaves 'Lys-63'-linked long polyubiquitin chains, Shows only weak activity against 'Lys-11' and 'Lys-48'-linked chains, Plays an important role in genome stability pathways, functioning to prevent spontaneous DNA damage and also promote cellular survival in response to exogenous DNA damage, Modulates the ubiquitination status of replication protein A (RPA) complex proteins in response to replication stress

Belongs to the peptidase C78 family, ZUFSP subfamily


This is Zinc finger protein 718 protein, from Human, contains 478 amino acids, has 11 C2H2-type Zinc finger.


This is Transcription elongation factor SPT4 protein, from Bovine, contains 117 amino acids, has 1 C4-type Zinc finger.

Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates mRNA processing and transcription elongation by RNA polymerase II, DSIF positively regulates mRNA capping by stimulating the mRNA guanylyltransferase activity of RNGTT/CAP1A, DSIF also acts cooperatively with the negative elongation factor complex (NELF complex) to enhance transcriptional pausing at sites proximal to the promoter, Transcriptional pausing may facilitate the assembly of an elongation competent RNA polymerase II complex, DSIF and NELF promote pausing by inhibition of the transcription elongation factor TFIIS/S-II, TFIIS/S-II binds to RNA polymerase II at transcription pause sites and stimulates the weak intrinsic nuclease activity of the enzyme, Cleavage of blocked transcripts by RNA polymerase II promotes the resumption of transcription from the new 3' terminus and may allow repeated attempts at transcription through natural pause sites (By similarity)


This is AN1-type zinc finger protein 6 protein, from Bovine, contains 208 amino acids, has 1 A20-type Zinc finger, has 1 AN1-type Zinc finger.


This is RNA-binding protein NOB1 protein, from Bovine, contains 413 amino acids, has 1 NOB1 Zinc finger.

May play a role in mRNA degradation (By similarity), Endonuclease required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits (By similarity)


This is THAP domain-containing protein 1 protein, from Bovine, contains 213 amino acids, has 1 THAP-type Zinc finger.

THAP-type

DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression, Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes, including RRM1, May also have pro-apoptotic activity by potentiating both serum-withdrawal and TNF-induced apoptosis (By similarity)


This is E3 ubiquitin-protein ligase RNF181 protein, from Bovine, contains 153 amino acids, has 1 RING-type; atypical Zinc finger.

RING-type; atypical

E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, Catalyzes monoubiquitination of 26S proteasome subunit PSMC2/RPT1


This is Non-structural maintenance of chromosomes element 1 homolog protein, from Bovine, contains 266 amino acids, has 1 RING-type; atypical Zinc finger.

RING-type; atypical

RING-type zinc finger-containing E3 ubiquitin ligase that assembles with melanoma antigen protein (MAGE) to catalyze the direct transfer of ubiquitin from E2 ubiquitin-conjugating enzyme to a specific substrate, Within MAGE-RING ubiquitin ligase complex, MAGE stimulates and specifies ubiquitin ligase activity likely through recruitment and/or stabilization of the E2 ubiquitin-conjugating enzyme at the E3:substrate complex, Involved in maintenance of genome integrity, DNA damage response and DNA repair, NSMCE3/MAGEG1 and NSMCE1 ubiquitin ligase are components of SMC5-SMC6 complex and may positively regulate homologous recombination-mediated DNA repair


This is E3 ubiquitin-protein ligase RNF186 protein, from Bovine, contains 226 amino acids, has 1 RING-type Zinc finger.

RING-type

E3 ubiquitin protein ligase that is part of an apoptotic signaling pathway activated by endoplasmic reticulum stress, Stimulates the expression of proteins specific of the unfolded protein response (UPR), ubiquitinates BNIP1 and regulates its localization to the mitochondrion and induces calcium release from the endoplasmic reticulum that ultimately leads to cell apoptosis, Plays a role in the maintenance of intestinal homeostasis and clearance of enteric pathogens, Upon NOD2 stimulation, ubiquitinates the ER stress sensor activating transcription factor 6/ATF6 and promotes the unfolded protein response UPR, Participates in basal level of autophagy maintenance by regulating the ubiquitination of EPHB2, Upon stimulation by ligand EFNB1, ubiquitinates EPHB2 and further recruits MAP1LC3B for autophagy induction, Controls nutrient sensing by ubiquitinating Sestrin-2/SESN2, which is an intracellular sensor of cytosolic leucine and inhibitor of mTORC1 activity


This is Transmembrane and immunoglobulin domain-containing protein 1 protein, from Bovine, contains 261 amino acids, has 2 Ig-like C2-type Immunoglobulin domain.

Ig-like C2-type

Ig-like C2-type

May control cell-cell adhesion, cell migration and proliferation, cell morphology, and protects renal epithelial cells from oxidative cell injury to promote cell survival


This is Zinc finger protein 691 protein, from Mouse, contains 283 amino acids, has 7 C2H2-type Zinc finger.


This is Tripartite motif-containing protein 43A protein, from Mouse, contains 445 amino acids, has 1 RING-type Zinc finger, has 1 B box-type Zinc finger.

RING-type

B box-type


This is Ankyrin repeat and MYND domain-containing protein 2 protein, from Mouse, contains 440 amino acids, has 1 MYND-type Zinc finger.

MYND-type

May be involved in the trafficking of signaling proteins to the cilia


This is tRNA (guanine(26)-N(2))-dimethyltransferase protein, from Mouse, contains 663 amino acids, has 1 C3H1-type Zinc finger.

Dimethylates a single guanine residue at position 26 of most tRNAs using S-adenosyl-L-methionine as donor of the methyl groups

Belongs to the class I-like SAM-binding methyltransferase superfamily, Trm1 family


This is Zinc finger protein 575 protein, from Mouse, contains 239 amino acids, has 6 C2H2-type Zinc finger.


This is Zinc finger protein 710 protein, from Mouse, contains 666 amino acids, has 11 C2H2-type Zinc finger.


This is E3 ubiquitin-protein ligase RNF166 protein, from Mouse, contains 237 amino acids, has 1 RING-type Zinc finger, has 1 C2HC RNF-type Zinc finger.

RING-type

C2HC RNF-type

E3 ubiquitin-protein ligase that promotes the ubiquitination of different substrates, In turn, participates in different biological processes including interferon production or autophagy, Plays a role in the activation of RNA virus-induced interferon-beta production by promoting the ubiquitination of TRAF3 and TRAF6, Also plays a role in the early recruitment of autophagy adapters to bacteria, Mediates 'Lys-29' and 'Lys-33'-linked ubiquitination of SQSTM1 leading to xenophagic targeting of bacteria and inhibition of their replication


This is RNA-binding protein MEX3D protein, from Mouse, contains 643 amino acids, has 1 RING-type Zinc finger.

RING-type

RNA binding protein, may be involved in post-transcriptional regulatory mechanisms


This is RING finger and transmembrane domain-containing protein 2 protein, from Mouse, contains 445 amino acids, has 1 RING-type Zinc finger.

RING-type


This is Zinc finger and SCAN domain containing protein 4F protein, from Mouse, contains 506 amino acids, has 4 C2H2-type Zinc finger.

Transcription factor required to regulate early development, Binds telomeres and plays a key role in genomic stability by regulating telomere elongation, Acts as an activator of spontaneous telomere sister chromatid exchange (T-SCE) and telomere elongation (By similarity)


This is Zinc finger protein 48 protein, from Mouse, contains 591 amino acids, has 12 C2H2-type Zinc finger.

May be involved in transcriptional regulation


This is Tripartite motif-containing protein 75 protein, from Mouse, contains 467 amino acids, has 1 RING-type Zinc finger, has 1 B box-type Zinc finger.

RING-type

B box-type


This is Zinc finger protein 583 protein, from Mouse, contains 568 amino acids, has 12 C2H2-type Zinc finger.


This is Zinc finger protein 148 protein, from Bovine, contains 794 amino acids, has 4 C2H2-type Zinc finger.

Involved in transcriptional regulation, Represses the transcription of a number of genes including gastrin, stromelysin and enolase, Binds to the G-rich box in the enhancer region of these genes (By similarity)


This is Chaperone protein DnaJ protein, from Ehrlichia canis (strain Jake), contains 382 amino acids, has 1 CR-type Zinc finger.

CR-type

Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion, Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex, GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle, Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding, Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins


This is Formamidopyrimidine-DNA glycosylase protein, from Shigella sonnei (strain Ss046), contains 269 amino acids, has 1 FPG-type Zinc finger.

FPG-type

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents, Acts as DNA glycosylase that recognizes and removes damaged bases, Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG), Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand, Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Shigella sonnei (strain Ss046), contains 304 amino acids, has 1 C4-type Zinc finger.

Component of the acetyl coenzyme A carboxylase (ACC) complex, Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA


This is Endonuclease 8 protein, from Shigella sonnei (strain Ss046), contains 263 amino acids, has 1 FPG-type Zinc finger.

FPG-type

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents, Acts as DNA glycosylase that recognizes and removes damaged bases, Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine, Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand, Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates


This is Chaperone protein DnaJ protein, from Shigella sonnei (strain Ss046), contains 376 amino acids, has 1 CR-type Zinc finger.

CR-type


This is DNA-directed RNA polymerases I, II, and III subunit RPABC4 protein, from Bovine, contains 58 amino acids, has 1 C4-type Zinc finger.

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates, Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and a small RNAs, such as 5S rRNA and tRNAs, respectively (By similarity)

Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family


This is Four and a half LIM domains protein 3 protein, from Bovine, contains 280 amino acids, has 1 C4-type Zinc finger.

Recruited by SOX15 to FOXK1 promoters where it acts as a transcriptional coactivator of FOXK1


This is Sodium channel modifier 1 protein, from Bovine, contains 230 amino acids, has 1 Matrin-type Zinc finger.

Matrin-type

As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs, Plays a role in the regulation of primary cilia length and Hedgehog signaling


This is Zinc finger CCCH domain-containing protein 14 protein, from Bovine, contains 735 amino acids, has 5 C3H1-type Zinc finger.

Involved in poly(A) tail length control in neuronal cells, Binds the polyadenosine RNA oligonucleotides


This is Zinc finger protein 1 protein, from Wheat, contains 261 amino acids, has 2 C2H2-type Zinc finger.

Potential transcription factor which binds the nonamer motif 5'-CATCCAACG-3', Possibly involved in regulating transcription of the histone H3 and H4 genes


This is Zinc finger protein ZAT7 protein, from Mouse-ear cress, contains 168 amino acids, has 2 C2H2-type Zinc finger.

Probable transcription factor involved in oxidative stress response


This is Zinc finger protein 1 protein, from Mouse-ear cress, contains 228 amino acids, has 1 C2H2-type Zinc finger.

May play a role in the regulation of shoot development, downstream of photomorphogenic activation (Probable), Acts as negative regulator of abscisic acid (ABA) signaling during germination and early seedling development (PubMed:24808098)


This is Large ribosomal subunit protein eL37y protein, from Mouse-ear cress, contains 95 amino acids, has 1 C4-type Zinc finger.

Belongs to the eukaryotic ribosomal protein eL37 family


This is Carbamoyltransferase HypF protein, from Azotobacter chroococcum mcd 1, contains 776 amino acids, has 2 C4-type Zinc finger.

Involved in the maturation of [NiFe] hydrogenases, Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases, HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide

Belongs to the carbamoyltransferase HypF family


This is Primosomal protein N' protein, from Borrelia burgdorferi, contains 660 amino acids, has 2 C4-type Zinc finger.

Involved in the restart of stalled replication forks, Recognizes and binds the arrested nascent DNA chain at stalled replication forks, It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA

Belongs to the helicase family, PriA subfamily


This is Chaperone protein DnaJ protein, from Bacillus stearothermophilus, contains 380 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Probable tRNA (uracil-O(2)-)-methyltransferase protein, from Caenorhabditis elegans, contains 563 amino acids, has 1 C3H1-type Zinc finger.

Probable adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase


This is Protein lin-28 homolog B protein, from Chicken, contains 250 amino acids, has 2 CCHC-type Zinc finger.

CCHC-type

CCHC-type

Suppressor of specific microRNA (miRNA) biogenesis, Binds target primary miRNA transcripts and sequester them in the nucleolus, away from the microprocessor complex, hence preventing their processing into mature miRNA, The specific interaction with target pri-miRNAs occurs via an 5'-GGAG-3' motif in the pre-miRNA terminal loop


This is Formamidopyrimidine-DNA glycosylase protein, from Prochlorococcus marinus (strain NATL2A), contains 282 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Prochlorococcus marinus (strain NATL2A), contains 294 amino acids, has 1 C4-type Zinc finger.


This is Chaperone protein DnaJ protein, from Cupriavidus necator (strain JMP 134), contains 379 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Formamidopyrimidine-DNA glycosylase protein, from Cupriavidus necator (strain JMP 134), contains 284 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Formamidopyrimidine-DNA glycosylase protein, from Dechloromonas aromatica (strain RCB), contains 277 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Dechloromonas aromatica (strain RCB), contains 289 amino acids, has 1 C4-type Zinc finger.


This is Formamidopyrimidine-DNA glycosylase protein, from Thermobifida fusca (strain YX), contains 296 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Chaperone protein DnaJ protein, from Vibrio psychroerythus, contains 378 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Vibrio psychroerythus, contains 285 amino acids, has 1 C4-type Zinc finger.


This is DNA repair protein RadA protein, from Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e), contains 457 amino acids, has 1 C4-type Zinc finger.

DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks, Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster, Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB, Does not have RecA's homology-searching function

Belongs to the RecA family, RadA subfamily


This is Formamidopyrimidine-DNA glycosylase protein, from Vibrio psychroerythus, contains 271 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Formamidopyrimidine-DNA glycosylase protein, from Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6), contains 270 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Chaperone protein DnaJ protein, from Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6), contains 380 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6), contains 306 amino acids, has 1 C4-type Zinc finger.


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Streptococcus pyogenes serotype M28 (strain MGAS6180), contains 288 amino acids, has 1 C4-type Zinc finger.


This is Formamidopyrimidine-DNA glycosylase protein, from Streptococcus pyogenes serotype M28 (strain MGAS6180), contains 275 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Blochmannia pennsylvanicus (strain BPEN), contains 294 amino acids, has 1 C4-type Zinc finger.


This is Chaperone protein DnaJ protein, from Blochmannia pennsylvanicus (strain BPEN), contains 375 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Zinc finger protein 404 protein, from Human, contains 552 amino acids, has 1 C2H2-type 1; degenerate Zinc finger, has 14 C2H2-type Zinc finger.

C2H2-type 1; degenerate

May be involved in transcriptional regulation


This is TRMT1-like protein protein, from Rat, contains 723 amino acids, has 1 C2H2-type Zinc finger.

May play a role in motor coordination and exploratory behavior


This is Chaperone protein DnaJ 2 protein, from Mycobacterium leprae (strain TN), contains 378 amino acids, has 1 CR-type Zinc finger.

CR-type

Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion, Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex, GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle, Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding, Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins


This is AN1-type zinc finger protein 3 protein, from Mouse, contains 227 amino acids, has 1 A20-type Zinc finger, has 1 AN1-type Zinc finger.


This is Zinc finger CCHC-type and RNA-binding motif-containing protein 1 protein, from Rat, contains 217 amino acids, has 1 CCHC-type Zinc finger.

CCHC-type


This is Zinc finger protein 672 protein, from Human, contains 452 amino acids, has 13 C2H2-type Zinc finger, has 1 C2H2-type 5; degenerate Zinc finger.

C2H2-type 5; degenerate


This is Zinc finger protein 69 homolog protein, from Human, contains 526 amino acids, has 9 C2H2-type Zinc finger.

Putative transcription factor that appears to regulate lipid metabolism


This is Zinc finger BED domain-containing protein 5 protein, from Human, contains 693 amino acids, has 1 BED-type Zinc finger.

BED-type


This is Teosinte glume architecture 1 protein, from Maize, contains 431 amino acids, has 1 SBP-type Zinc finger.

SBP-type

SBP transcriptional regulator probably involved in the domestication of maize (PubMed:16079849), Acts as a transcriptional repressor binding to a 5'-GTAC-3' motif (PubMed:25943393), May repress the growth of lateral branches in length and numbers (PubMed:25943393)


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic protein, from Tasmanian blue gum, contains 490 amino acids, has 1 C4-type Zinc finger.

Component of the acetyl coenzyme A carboxylase (ACC) complex, Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA


This is host range factor p28 protein, from VACV, contains 239 amino acids, has 1 RING-type Zinc finger.

RING-type

RING-finger E3 ubiquitin ligase which catalyzes the formation of both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains, Plays an important role in virulence by acting as an anti-apoptotic factor

Belongs to the orthopoxvirus OPG021 family


This is Chaperone protein DnaJ protein, from Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229 / NCIMB 8711 / NCTC 7292 / S-41), contains 378 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229 / NCIMB 8711 / NCTC 7292 / S-41), contains 288 amino acids, has 1 C4-type Zinc finger.


This is Structure-specific endonuclease subunit SLX1 homolog 2 protein, from Trypanosoma cruzi (strain CL Brener), contains 530 amino acids, has 1 SLX1-type Zinc finger.

Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination, Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA


This is Structure-specific endonuclease subunit SLX1 homolog 1 protein, from Trypanosoma cruzi (strain CL Brener), contains 529 amino acids, has 1 SLX1-type Zinc finger.


This is E3 ubiquitin-protein ligase XBAT33 protein, from Mouse-ear cress, contains 513 amino acids, has 1 RING-type Zinc finger.

RING-type

Possesses E3 ubiquitin-protein ligase activity when associated with the E2 enzyme UBC8 in vitro


This is Chaperone protein DnaJ protein, from Pelagibacter ubique (strain HTCC1062), contains 376 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Psychrobacter arcticus (strain DSM 17307 / VKM B-2377 / 273-4), contains 317 amino acids, has 1 C4-type Zinc finger.


This is Formamidopyrimidine-DNA glycosylase protein, from Psychrobacter arcticus (strain DSM 17307 / VKM B-2377 / 273-4), contains 309 amino acids, has 1 FPG-type Zinc finger.

FPG-type

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents, Acts as DNA glycosylase that recognizes and removes damaged bases, Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG), Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand, Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates


This is Chaperone protein DnaJ protein, from Psychrobacter arcticus (strain DSM 17307 / VKM B-2377 / 273-4), contains 374 amino acids, has 1 CR-type Zinc finger.

CR-type


This is RPA-interacting protein protein, from Rat, contains 219 amino acids, has 1 RIP-type Zinc finger.

RIP-type

Mediates the import of RPA complex into the nucleus, possibly via some interaction with importin beta, Sumoylation mediates the localization of RPA complex into the PML body of the nucleus, thereby participating in RPA function in DNA metabolism (By similarity)


This is 5'-3' exoribonuclease 2 protein, from Wheat head blight fungus, contains 980 amino acids, has 1 CCHC-type Zinc finger.

CCHC-type

Possesses 5'->3' exoribonuclease activity, Required for the processing of nuclear mRNA and rRNA precursors, May promote termination of transcription by RNA polymerase II (By similarity)

Belongs to the 5'-3' exonuclease family, XRN2/RAT1 subfamily


This is E3 ubiquitin-protein ligase BRE1 protein, from Wheat head blight fungus, contains 703 amino acids, has 1 RING-type Zinc finger.

RING-type

E3 ubiquitin-protein ligase that mediates monoubiquitination of histone H2B to form H2BK123ub1, H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation


This is Large ribosomal subunit protein eL24 protein, from Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770), contains 62 amino acids, has 1 C4-type Zinc finger.

Belongs to the eukaryotic ribosomal protein eL24 family


This is Probable E3 ubiquitin-protein ligase XBOS36 protein, from Rice, contains 420 amino acids, has 1 RING-type Zinc finger.

RING-type


This is mRNA export factor ICP27 homolog protein, from HHV-3, contains 452 amino acids, has 1 CHC2-type Zinc finger.

Multifunctional regulator of the expression of viral genes that mediates nuclear export of viral intronless mRNAs, This immediate early (EI) protein promotes the nuclear export of viral intronless mRNAs by interacting with mRNAs and host NXF1/TAP (By similarity)

Belongs to the HHV-1 ICP27 protein family


This is Formamidopyrimidine-DNA glycosylase protein, from Corynebacterium jeikeium (strain K411), contains 288 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Formamidopyrimidine-DNA glycosylase protein, from Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5), contains 270 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5), contains 306 amino acids, has 1 C4-type Zinc finger.


This is Chaperone protein DnaJ protein, from Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5), contains 374 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Zinc finger protein with KRAB and SCAN domains 1 protein, from Rat, contains 562 amino acids, has 6 C2H2-type Zinc finger.


This is ADP-ribosylation factor GTPase-activating protein 3 protein, from Rat, contains 525 amino acids, has 1 C4-type Zinc finger.

GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1), Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes (By similarity)


This is E3 ubiquitin-protein ligase RNF217 protein, from African clawed frog, contains 282 amino acids, has 1 RING-type Zinc finger, has 1 IBR-type Zinc finger, has 1 RING-type 2; atypical Zinc finger.

RING-type

IBR-type

RING-type 2; atypical

E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, Mediates the degradation of the iron exporter ferroportin/SLC40A1 and thus regulates iron homeostasis

Belongs to the RBR family, RNF217 subfamily


This is Probable tRNA (uracil-O(2)-)-methyltransferase protein, from African clawed frog, contains 668 amino acids, has 1 C3H1-type Zinc finger.

Probable adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase


This is V-set and immunoglobulin domain-containing protein 1 protein, from Rat, contains 404 amino acids, has 1 Ig-like V-type Immunoglobulin domain, has 1 Ig-like C2-type Immunoglobulin domain.

Ig-like V-type

Ig-like C2-type


This is Protein M2-1 protein, from Human respiratory syncytial virus, contains 194 amino acids, has 1 C3H1-type Zinc finger.

Acts as a tetrameric transcription processivity factor that binds in a competitive manner to RNA and the phosphoprotein (P) to prevent premature termination during transcription, Transcription anti-terminator that enhances readthrough of intergenic junctions during viral transcription, Preferentially binds to poly(A)-rich sequences, Plays a role in the association of the matrix protein with the nucleocapsid, which initiates assembly and budding, Also, can activate host NF-kappa-B through association with host RELA

Belongs to the pneumoviridae M2-1 protein family


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Staphylococcus haemolyticus (strain JCSC1435), contains 288 amino acids, has 1 C4-type Zinc finger.


This is Branchpoint-bridging protein protein, from Corn smut fungus, contains 625 amino acids, has 2 CCHC-type Zinc finger.

CCHC-type

CCHC-type

Necessary for the splicing of pre-mRNA, Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns (By similarity)


This is U1 small nuclear ribonucleoprotein C protein, from Corn smut fungus, contains 221 amino acids, has 1 Matrin-type Zinc finger.

Matrin-type

Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome, U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing, The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA, Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region

Belongs to the U1 small nuclear ribonucleoprotein C family


This is E3 ubiquitin-protein ligase BRE1 protein, from Corn smut fungus, contains 817 amino acids, has 1 RING-type Zinc finger.

RING-type


This is JmjC domain-containing histone demethylation protein 1 protein, from Corn smut fungus, contains 669 amino acids, has 1 PHD-type Zinc finger.

PHD-type

Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code

Belongs to the JHDM1 histone demethylase family


This is Pre-mRNA-splicing factor CWC2 protein, from Corn smut fungus, contains 465 amino acids, has 1 C3H1-type Zinc finger.

Involved in the first step of pre-mRNA splicing, Required for cell growth and cell cycle control, Plays a role in the levels of the U1, U4, U5 and U6 snRNAs and the maintenance of the U4/U6 snRNA complex, May provide the link between the 'nineteen complex' NTC spliceosome protein complex and the spliceosome through the U6 snRNA, Associates predominantly with U6 snRNAs in assembled active spliceosomes, Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle (By similarity)


This is Pre-mRNA-splicing factor SLT11 protein, from Corn smut fungus, contains 324 amino acids, has 1 C3H1-type Zinc finger.

Involved in pre-mRNA splicing, Facilitates the cooperative formation of U2/U6 helix II in association with stem II in the spliceosome, Binds to RNA (By similarity)


This is FCS-Like Zinc finger 16 protein, from Mouse-ear cress, contains 124 amino acids, has 1 FLZ-type Zinc finger.

FLZ-type

May act as an adapter to facilitate the interaction of SnRK1 complex with effector proteins, conferring tissue- and stimulus-type specific differences in the SnRK1 regulation pathway


This is Structure-specific endonuclease subunit SLX1 homolog protein, from Leishmania major, contains 704 amino acids, has 1 SLX1-type Zinc finger.

Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination, Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA


This is Chaperone protein DnaJ protein, from Haemophilus influenzae (strain 86-028NP), contains 381 amino acids, has 1 CR-type Zinc finger.

CR-type

Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion, Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex, GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle, Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding, Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Haemophilus influenzae (strain 86-028NP), contains 296 amino acids, has 1 C4-type Zinc finger.

Component of the acetyl coenzyme A carboxylase (ACC) complex, Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA


This is Formamidopyrimidine-DNA glycosylase protein, from Haemophilus influenzae (strain 86-028NP), contains 271 amino acids, has 1 FPG-type Zinc finger.

FPG-type

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents, Acts as DNA glycosylase that recognizes and removes damaged bases, Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG), Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand, Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates


This is Methionine aminopeptidase 1 protein, from Zebrafish, contains 386 amino acids, has 1 C6H2-type Zinc finger.

Cotranslationally removes the N-terminal methionine from nascent proteins, The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val)

Belongs to the peptidase M24A family, Methionine aminopeptidase type 1 subfamily


This is Zinc finger protein 541 protein, from Crab-eating macaque, contains 804 amino acids, has 2 C2H2-type Zinc finger.

Component of some chromatin remodeling multiprotein complex that plays a role during spermatogenesis


This is Transcription factor IIIB 50 kDa subunit protein, from Crab-eating macaque, contains 373 amino acids, has 1 TFIIB-type Zinc finger.

TFIIB-type

General activator of RNA polymerase III transcription, Factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites, Contributes to the regulation of gene expression; functions as activator in the absence of oxidative stress, Down-regulates expression of target genes in response to oxidative stress, Overexpression protects cells against apoptosis in response to oxidative stress


This is E3 ubiquitin-protein ligase CBLL2 protein, from Crab-eating macaque, contains 422 amino acids, has 1 RING-type Zinc finger, has 1 C2H2-type Zinc finger.

RING-type

E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins, May operate on tyrosine-phosphorylated SRC substrates


This is THAP domain-containing protein 1 protein, from Crab-eating macaque, contains 212 amino acids, has 1 THAP-type Zinc finger.

THAP-type

DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression, Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes, including RRM1, Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1, May also have pro-apoptotic activity by potentiating both serum-withdrawal and TNF-induced apoptosis (By similarity)


This is Zinc finger protein 14 protein, from Crab-eating macaque, contains 642 amino acids, has 17 C2H2-type Zinc finger, has 1 C2H2-type 2; degenerate Zinc finger, has 1 C2H2-type 4; atypical Zinc finger.

C2H2-type 2; degenerate

C2H2-type 4; atypical

May be involved in transcriptional regulation

Belongs to the krueppel C2H2-type zinc-finger protein family


This is ADP-ribosylation factor GTPase-activating protein 3 protein, from Crab-eating macaque, contains 516 amino acids, has 1 C4-type Zinc finger.

GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1), Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes (By similarity)


This is Pre-mRNA-splicing factor SLU7 protein, from Crab-eating macaque, contains 586 amino acids, has 1 CCHC-type Zinc finger.

CCHC-type

Required for pre-mRNA splicing as component of the spliceosome, Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron, Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region, May be involved in the activation of proximal AG, Probably also involved in alternative splicing regulation


This is RNA-binding protein NOB1 protein, from Crab-eating macaque, contains 412 amino acids, has 1 NOB1 Zinc finger.

May play a role in mRNA degradation (By similarity), Endonuclease required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits (By similarity)


This is TATA box-binding protein-associated factor RNA polymerase I subunit B protein, from Crab-eating macaque, contains 588 amino acids, has 1 RRN7-type Zinc finger.

Component of RNA polymerase I core factor complex that acts as a GTF2B/TFIIB-like factor and plays a key role in multiple steps during transcription initiation such as pre-initiation complex (PIC) assembly and postpolymerase recruitment events in polymerase I (Pol I) transcription, Binds rDNA promoters and plays a role in Pol I recruitment as a component of the SL1/TIF-IB complex and, possibly, directly through its interaction with RRN3 (By similarity)


This is Zinc finger CCCH domain-containing protein 14 protein, from Crab-eating macaque, contains 736 amino acids, has 5 C3H1-type Zinc finger.

Involved in poly(A) tail length control in neuronal cells, Binds the polyadenosine RNA oligonucleotides


This is THAP domain-containing protein 5 protein, from Crab-eating macaque, contains 396 amino acids, has 1 THAP-type Zinc finger.

THAP-type

Has sequence-specific DNA-binding activity and can function as transcriptional repressor (in vitro), May be a regulator of cell cycle: THAP5 overexpression in human cell lines causes cell cycle arrest at G2/M phase


This is Zinc finger protein 322 protein, from Crab-eating macaque, contains 402 amino acids, has 1 C2H2-type 1; atypical Zinc finger, has 8 C2H2-type Zinc finger, has 1 C2H2-type 10; degenerate Zinc finger, has 1 C2H2-type 11; degenerate Zinc finger.

C2H2-type 1; atypical

C2H2-type 10; degenerate

C2H2-type 11; degenerate

Transcriptional activator, Important for maintenance of pluripotency in embryonic stem cells, Binds directly to the POU5F1 distal enhancer and the NANOG proximal promoter, and enhances expression of both genes, Can also bind to numerous other gene promoters and regulates expression of many other pluripotency factors, either directly or indirectly, Promotes inhibition of MAPK signaling during embryonic stem cell differentiation


This is Neurotrophin receptor-interacting factor homolog protein, from Crab-eating macaque, contains 653 amino acids, has 5 C2H2-type Zinc finger.

Probable transcription repressor, Specifically binds to the 3'-end of zinc-finger coding genes and recruiting chromatin-modifying proteins such as SETDB1 and TRIM28/KAP1, leading to transcription repression, The SETDB1-TRIM28-ZNF274 complex may play a role in recruiting ATRX to the 3'-exons of zinc-finger coding genes with atypical chromatin signatures to establish or maintain/protect H3K9me3 at these transcriptionally active regions (By similarity)


This is Zinc finger protein 574 protein, from Crab-eating macaque, contains 896 amino acids, has 19 C2H2-type Zinc finger, has 1 C2H2-type 15; degenerate Zinc finger.

C2H2-type 15; degenerate


This is Transcription elongation factor SPT4 protein, from Crab-eating macaque, contains 117 amino acids, has 1 C4-type Zinc finger.

Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates mRNA processing and transcription elongation by RNA polymerase II, DSIF positively regulates mRNA capping by stimulating the mRNA guanylyltransferase activity of RNGTT/CAP1A, DSIF also acts cooperatively with the negative elongation factor complex (NELF complex) to enhance transcriptional pausing at sites proximal to the promoter, Transcriptional pausing may facilitate the assembly of an elongation competent RNA polymerase II complex, DSIF and NELF promote pausing by inhibition of the transcription elongation factor TFIIS/S-II, TFIIS/S-II binds to RNA polymerase II at transcription pause sites and stimulates the weak intrinsic nuclease activity of the enzyme, Cleavage of blocked transcripts by RNA polymerase II promotes the resumption of transcription from the new 3' terminus and may allow repeated attempts at transcription through natural pause sites (By similarity)


This is G2/M phase-specific E3 ubiquitin-protein ligase protein, from Crab-eating macaque, contains 706 amino acids, has 1 C2HC pre-PHD-type Zinc finger, has 2 PHD-type Zinc finger, has 1 PHD-type 2; degenerate Zinc finger.

C2HC pre-PHD-type

PHD-type

PHD-type 2; degenerate

PHD-type

E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, Essential in early embryonic development to prevent apoptotic death


This is Chaperone protein DnaJ protein, from Rickettsia azadi, contains 371 amino acids, has 1 CR-type Zinc finger.

CR-type

Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion, Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex, GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle, Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding, Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins


This is DNA primase protein, from Rickettsia azadi, contains 595 amino acids, has 1 CHC2-type Zinc finger.

RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication


This is UvrABC system protein A protein, from Rickettsia azadi, contains 955 amino acids, has 1 C4-type Zinc finger.

The UvrABC repair system catalyzes the recognition and processing of DNA lesions, UvrA is an ATPase and a DNA-binding protein, A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities, When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate

Belongs to the ABC transporter superfamily, UvrA family


This is DNA repair protein RadA protein, from Rickettsia azadi, contains 446 amino acids, has 1 C4-type Zinc finger.

DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks, Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster, Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB, Does not have RecA's homology-searching function


This is Primosomal protein N' protein, from Rickettsia azadi, contains 648 amino acids, has 2 C4-type Zinc finger.

Involved in the restart of stalled replication forks, Recognizes and binds the arrested nascent DNA chain at stalled replication forks, It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA


This is Formamidopyrimidine-DNA glycosylase protein, from Rickettsia azadi, contains 276 amino acids, has 1 FPG-type Zinc finger.

FPG-type

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents, Acts as DNA glycosylase that recognizes and removes damaged bases, Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG), Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand, Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates


This is Formamidopyrimidine-DNA glycosylase protein, from Xanthomonas campestris pv. campestris (strain 8004), contains 271 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Chaperone protein DnaJ protein, from Xanthomonas campestris pv. campestris (strain 8004), contains 376 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Xanthomonas campestris pv. campestris (strain 8004), contains 295 amino acids, has 1 C4-type Zinc finger.

Component of the acetyl coenzyme A carboxylase (ACC) complex, Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA


This is PHD finger protein 10 protein, from Rat, contains 497 amino acids, has 1 PHD-type 1; degenerate Zinc finger, has 1 PHD-type 2; degenerate Zinc finger.

PHD-type 1; degenerate

PHD-type 2; degenerate

Involved in transcription activity regulation by chromatin remodeling, Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and is required for the proliferation of neural progenitors, During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state, The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes, As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF), The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells, The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity)


This is Polyhomeotic-like protein 2 protein, from African clawed frog, contains 344 amino acids, has 1 FCS-type Zinc finger.

FCS-type

Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development, PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility (By similarity)


This is Single Ig IL-1-related receptor protein, from Rat, contains 409 amino acids, has 1 Ig-like C2-type Immunoglobulin domain.

Ig-like C2-type

Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways, Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4, Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP (By similarity)

Belongs to the interleukin-1 receptor family


This is Zinc finger protein 90 protein, from Rat, contains 633 amino acids, has 13 C2H2-type Zinc finger.

Inhibits the transcriptional repressor activity of REST by inhibiting its binding to DNA, thereby derepressing transcription of REST target genes


This is Protein SREK1IP1 protein, from Mouse, contains 153 amino acids, has 1 CCHC-type Zinc finger.

CCHC-type

Possible splicing regulator involved in the control of cellular survival


This is Zinc finger protein 664 protein, from Mouse, contains 261 amino acids, has 9 C2H2-type Zinc finger.

May be involved in transcriptional regulation


This is Probable E3 ubiquitin-protein ligase makorin-1 protein, from Zebrafish, contains 439 amino acids, has 4 C3H1-type Zinc finger, has 1 RING-type Zinc finger.

RING-type

E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins


This is Forkhead box protein P4 protein, from African clawed frog, contains 641 amino acids, has 1 C2H2-type Zinc finger.


This is E3 ubiquitin-protein ligase bre1 protein, from Neosartorya fumigata, contains 725 amino acids, has 1 RING-type Zinc finger.

RING-type

E3 ubiquitin-protein ligase that mediates monoubiquitination of histone H2B to form H2BK123ub1, H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation


This is Structure-specific endonuclease subunit slx1 protein, from Neosartorya fumigata, contains 423 amino acids, has 1 SLX1-type Zinc finger.

Catalytic subunit of the slx1-slx4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination, Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA


This is Vacuolar protein sorting-associated protein 27 protein, from Neosartorya fumigata, contains 729 amino acids, has 1 FYVE-type; degenerate Zinc finger.

FYVE-type; degenerate

Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane


This is U1 small nuclear ribonucleoprotein C protein, from Neosartorya fumigata, contains 216 amino acids, has 1 Matrin-type Zinc finger.

Matrin-type

Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome, U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing, The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA, Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region


This is C2H2 type master regulator of conidiophore development brlA protein, from Neosartorya fumigata, contains 426 amino acids, has 2 C2H2-type Zinc finger.

BrlA, abaA and wetA are pivotal regulators of conidiophore development and conidium maturation (PubMed:17030990), They act individually and together to regulate their own expression and that of numerous other sporulation-specific genes (By similarity), Binds promoters of target genes at brlA response elements (BREs) containing the conserved sequence 5'-(C/A)(A/G)AGGG(G/A)-3' (By similarity), Positively regulates expression of the gliotoxin biosynthetic gene cluster in actively growing vegetative cells, and likely bridges morphological and chemical development during the life-cycle (PubMed:26032501), Regulates (directly or indirectly) the ergot cluster genes (PubMed:18333504), Positively regulates expression of the fumiquinazoline C biosynthetic gene cluster (PubMed:24612080), Positively regulates expression of the melanin biosynthetic gene cluster (PubMed:24123270), Mediates repression of ribosomal protein gene expression in response to nitrogen depletion (PubMed:19028996)


This is Protein fyv10 protein, from Neosartorya fumigata, contains 411 amino acids, has 1 RING-Gid-type Zinc finger.

RING-Gid-type

Involved in the proteasome-dependent degradation of fructose-1,6-bisphosphatase


This is Transcription elongation factor spt4 protein, from Neosartorya fumigata, contains 156 amino acids, has 1 C4-type Zinc finger.

The spt4-spt5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing, This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene (By similarity)


This is Pre-mRNA-splicing factor cwc2 protein, from Neosartorya fumigata, contains 414 amino acids, has 1 C3H1-type Zinc finger.

Involved in the first step of pre-mRNA splicing, Required for cell growth and cell cycle control, Plays a role in the levels of the U1, U4, U5 and U6 snRNAs and the maintenance of the U4/U6 snRNA complex, May provide the link between the 'nineteen complex' NTC spliceosome protein complex and the spliceosome through the U6 snRNA, Associates predominantly with U6 snRNAs in assembled active spliceosomes, Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle (By similarity)


This is MYND-type zinc finger protein samB protein, from Neosartorya fumigata, contains 605 amino acids, has 1 MYND-type; degenerate Zinc finger.

MYND-type; degenerate

Involved in determination of the onset of polarized growth and morphogenesis, Plays a role in the regulation of branching in hyphae and spore formation (By similarity)


This is C2H2 finger domain transcription factor dvrA protein, from Neosartorya fumigata, contains 679 amino acids, has 2 C2H2-type Zinc finger.

Transcription factor that seems to function as negative regulators of virulence by affecting the capacity to damage host cells and to stimulate a pro-inflammatory response


This is Branchpoint-bridging protein protein, from Neosartorya fumigata, contains 566 amino acids, has 2 CCHC-type Zinc finger.

CCHC-type

CCHC-type

Necessary for the splicing of pre-mRNA, Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns (By similarity)


This is pH-response transcription factor pacC/RIM101 protein, from Neosartorya fumigata, contains 676 amino acids, has 3 C2H2-type Zinc finger.

Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH, At alkaline ambient pH, activates transcription of alkaline-expressed genes (including pacC itself) and represses transcription of acid-expressed genes (By similarity)


This is Postreplication repair E3 ubiquitin-protein ligase rad18 protein, from Neosartorya fumigata, contains 418 amino acids, has 1 RING-type Zinc finger, has 1 UBZ4-type Zinc finger.

RING-type

E3 RING-finger protein, member of the UBC2/RAD6 epistasis group, Associates to the E2 ubiquitin conjugating enzyme UBC2/RAD6 to form the UBC2-RAD18 ubiquitin ligase complex involved in postreplicative repair (PRR) of damaged DNA


This is Probable DNA-binding protein creA protein, from Neosartorya fumigata, contains 424 amino acids, has 2 C2H2-type Zinc finger.

Transcription regulator component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB, Represses the transcription of the alcR, alcA and aldA genes by binding to a GC-rich region in their promoter, Also plays a role in response to carbon starvation and the control of extracellular proteases activity (By similarity)

Belongs to the creA/MIG C2H2-type zinc-finger protein family


This is U1 small nuclear ribonucleoprotein C protein, from Plasmodium chabaudi, contains 192 amino acids, has 1 Matrin-type Zinc finger.

Matrin-type


This is U1 small nuclear ribonucleoprotein C protein, from Plasmodium berghei (strain Anka), contains 197 amino acids, has 1 Matrin-type Zinc finger.

Matrin-type


This is Formamidopyrimidine-DNA glycosylase protein, from Pseudomonas syringae pv. syringae (strain B728a), contains 270 amino acids, has 1 FPG-type Zinc finger.

FPG-type

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents, Acts as DNA glycosylase that recognizes and removes damaged bases, Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG), Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand, Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates


This is Chaperone protein DnaJ protein, from Pseudomonas syringae pv. syringae (strain B728a), contains 380 amino acids, has 1 CR-type Zinc finger.

CR-type

Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion, Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex, GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle, Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding, Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Pseudomonas syringae pv. syringae (strain B728a), contains 306 amino acids, has 1 C4-type Zinc finger.

Component of the acetyl coenzyme A carboxylase (ACC) complex, Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA


This is ERI1 exoribonuclease 2 protein, from Zebrafish, contains 555 amino acids, has 1 GRF-type Zinc finger.

GRF-type


This is Tripartite motif-containing 13 protein, from Zebrafish, contains 404 amino acids, has 1 RING-type Zinc finger, has 1 B box-type Zinc finger.

RING-type

B box-type

E3 ubiquitin ligase involved in the retrotranslocation and turnover of membrane and secretory proteins from the ER through a set of processes named ER-associated degradation (ERAD), This process acts on misfolded proteins as well as in the regulated degradation of correctly folded proteins (By similarity)


This is Transcriptional adapter 2-beta protein, from Zebrafish, contains 486 amino acids, has 1 ZZ-type Zinc finger.

ZZ-type


This is Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 2 protein, from Zebrafish, contains 561 amino acids, has 1 Ig-like Immunoglobulin domain.

Ig-like


This is Zinc finger protein 574 protein, from Rat, contains 898 amino acids, has 19 C2H2-type Zinc finger, has 1 C2H2-type 15; degenerate Zinc finger.

C2H2-type 15; degenerate

May be involved in transcriptional regulation


This is Tripartite motif-containing protein 67 protein, from Mouse, contains 768 amino acids, has 1 RING-type; degenerate Zinc finger, has 1 B box-type 1; degenerate Zinc finger, has 1 B box-type Zinc finger.

RING-type; degenerate

B box-type 1; degenerate

B box-type


This is UvrABC system protein A protein, from Neisseria gonorrhoeae, contains 950 amino acids, has 2 C4-type Zinc finger.

The UvrABC repair system catalyzes the recognition and processing of DNA lesions, UvrA is an ATPase and a DNA-binding protein, A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities, When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate


This is Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 protein, from Chicken, contains 613 amino acids, has 1 Ig-like C2-type Immunoglobulin domain.

Ig-like C2-type

Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors, Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination (By similarity)


This is Leucine-rich repeat-containing protein 24 protein, from Human, contains 513 amino acids, has 1 Ig-like C2-type Immunoglobulin domain.

Ig-like C2-type


This is Pre-mRNA-splicing factor CWC2 protein, from Rice blast fungus, contains 394 amino acids, has 1 C3H1-type Zinc finger.


This is Chaperone protein DnaJ protein, from Rhodopseudomonas capsulata, contains 384 amino acids, has 1 CR-type Zinc finger.

CR-type


This is pH-response transcription factor pacC/RIM101 protein, from Rice blast fungus, contains 559 amino acids, has 3 C2H2-type Zinc finger.

Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH, At alkaline ambient pH, activates transcription of alkaline-expressed genes (including RIM101 itself) and represses transcription of acid-expressed genes (By similarity)


This is Zinc finger and BTB domain-containing protein 24 protein, from Zebrafish, contains 672 amino acids, has 8 C2H2-type Zinc finger.

May be involved in BMP2-induced transcription


This is Zinc finger protein 585B protein, from Human, contains 769 amino acids, has 21 C2H2-type Zinc finger.


This is Zinc-finger homeodomain protein 4 protein, from Rice, contains 417 amino acids, has 1 ZF-HD dimerization-type; degenerate Zinc finger.

ZF-HD dimerization-type; degenerate


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Anacystis nidulans R2, contains 305 amino acids, has 1 C4-type Zinc finger.


This is Splicing factor 3A subunit 2 protein, from Social amoeba, contains 215 amino acids, has 1 Matrin-type Zinc finger.

Matrin-type

Involved in pre-mRNA splicing as a component of the splicing factor SF3A complex that contributes to the assembly of the 17S U2 snRNP, and the subsequent assembly of the pre-spliceosome 'E' complex and the pre-catalytic spliceosome 'A' complex, Involved in pre-mRNA splicing as a component of pre-catalytic spliceosome 'B' complexes, including the Bact complex


This is tRNA:m(4)X modification enzyme TRM13 homolog protein, from Social amoeba, contains 525 amino acids, has 1 CHHC U11-48K-type Zinc finger.

CHHC U11-48K-type

tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His)

Belongs to the methyltransferase TRM13 family


This is Branchpoint-bridging protein protein, from Social amoeba, contains 501 amino acids, has 1 CCHC-type Zinc finger.

CCHC-type


This is Uncharacterized protein DDB_G0292642 protein, from Social amoeba, contains 903 amino acids, has 1 RING-type Zinc finger, has 1 IBR-type Zinc finger, has 1 RING-type 2; atypical Zinc finger.

RING-type

IBR-type

RING-type 2; atypical


This is Putative E3 ubiquitin-protein ligase ubr7 protein, from Social amoeba, contains 465 amino acids, has 1 UBR-type Zinc finger, has 1 PHD-type Zinc finger.

UBR-type

PHD-type


This is Transcription initiation factor IIB protein, from Social amoeba, contains 325 amino acids, has 1 TFIIB-type Zinc finger.

TFIIB-type

General transcription factor that plays a role in transcription initiation by RNA polymerase II (Pol II), Involved in the pre-initiation complex (PIC) formation and Pol II recruitment at promoter DNA


This is SET and MYND domain-containing protein DDB_G0288495 protein, from Social amoeba, contains 532 amino acids, has 1 MYND-type; degenerate Zinc finger.

MYND-type; degenerate

Belongs to the class V-like SAM-binding methyltransferase superfamily


This is RING-box protein 1 protein, from Social amoeba, contains 104 amino acids, has 1 RING-type; degenerate Zinc finger.

RING-type; degenerate

Component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex, which mediates the ubiquitination and subsequent proteasomal degradation of target proteins, Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme to the complex and brings it into close proximity to the substrate (By similarity)


This is Probable ATP-dependent RNA helicase ddx41 protein, from Social amoeba, contains 671 amino acids, has 1 CCHC-type Zinc finger.

CCHC-type

Belongs to the DEAD box helicase family, DDX41 subfamily


This is Anaphase-promoting complex subunit 11 protein, from Social amoeba, contains 87 amino acids, has 1 RING-type; atypical Zinc finger.

RING-type; atypical

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle


This is Putative peroxisome assembly protein 12 protein, from Social amoeba, contains 459 amino acids, has 1 RING-type; degenerate Zinc finger.

RING-type; degenerate

Component of a retrotranslocation channel required for peroxisome organization by mediating export of the PEX5 receptor from peroxisomes to the cytosol, thereby promoting PEX5 recycling (By similarity), The retrotranslocation channel is composed of PEX2, PEX10 and PEX12; each subunit contributing transmembrane segments that coassemble into an open channel that specifically allows the passage of PEX5 through the peroxisomal membrane (By similarity), PEX12 also regulates PEX5 recycling by activating the E3 ubiquitin-protein ligase activity of PEX10 (By similarity), When PEX5 recycling is compromised, PEX12 stimulates PEX10-mediated polyubiquitination of PEX5, leading to its subsequent degradation (By similarity)


This is Pre-mRNA-splicing factor cwc2 protein, from Social amoeba, contains 528 amino acids, has 1 C3H1-type Zinc finger.

Involved in pre-mRNA splicing, Binds RNA (By similarity)


This is DNA-directed RNA polymerases I, II, and III subunit rpabc4 protein, from Social amoeba, contains 46 amino acids, has 1 C4-type Zinc finger.

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates, Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and a small RNAs, such as 5S rRNA and tRNAs, respectively (By similarity)

Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family


This is Eukaryotic translation initiation factor 2 subunit 2 protein, from Social amoeba, contains 317 amino acids, has 1 C4-type Zinc finger.

eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA, This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex, Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex, In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B (By similarity)


This is Pre-mRNA-splicing factor slu7 protein, from Social amoeba, contains 558 amino acids, has 1 CCHC-type Zinc finger.

CCHC-type

Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron


This is Methionine aminopeptidase 1 protein, from Social amoeba, contains 367 amino acids, has 1 C6H2-type Zinc finger.

Cotranslationally removes the N-terminal methionine from nascent proteins, The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val)


This is U1 small nuclear ribonucleoprotein C protein, from Social amoeba, contains 174 amino acids, has 1 Matrin-type Zinc finger.

Matrin-type

Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome, SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing, The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA, Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region


This is Transcription elongation factor A protein 1 protein, from Social amoeba, contains 319 amino acids, has 1 TFIIS-type Zinc finger.

TFIIS-type

Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites, The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes, Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus (By similarity)


This is Vacuolar protein sorting-associated protein 11 homolog protein, from Social amoeba, contains 952 amino acids, has 1 RING-type; atypical Zinc finger.

RING-type; atypical

May play a role in vesicle-mediated protein trafficking


This is Chaperone protein DnaJ 1 protein, from Synechocystis sp. (strain PCC 6803 / Kazusa), contains 377 amino acids, has 1 CR-type Zinc finger.

CR-type

Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion, Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex, GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle, Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding, Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins


This is Carbamoyltransferase HypF protein, from Synechocystis sp. (strain PCC 6803 / Kazusa), contains 767 amino acids, has 2 C4-type Zinc finger.

Involved in the maturation of [NiFe] hydrogenases, Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases, HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide

Belongs to the carbamoyltransferase HypF family


This is General transcription factor IIE subunit 1 protein, from Social amoeba, contains 456 amino acids, has 1 C4-type Zinc finger.

Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH, Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase (By similarity)

Belongs to the TFIIE alpha subunit family


This is Uncharacterized protein DDB_G0272420 protein, from Social amoeba, contains 360 amino acids, has 1 C3H1-type Zinc finger.


This is Ubiquitin thioesterase OTU1 protein, from Social amoeba, contains 325 amino acids, has 1 C2H2-type Zinc finger.

Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation


This is General transcription factor IIH subunit 3 protein, from Rat, contains 309 amino acids, has 1 C4-type Zinc finger.

Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II, In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment, In transcription, TFIIH has an essential role in transcription initiation, When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape, Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription


This is UvrABC system protein A protein, from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8), contains 952 amino acids, has 2 C4-type Zinc finger.

The UvrABC repair system catalyzes the recognition and processing of DNA lesions, UvrA is an ATPase and a DNA-binding protein, A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities, When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate


This is Transcription factor S protein, from Thermococcus celer, contains 110 amino acids, has 1 C4-type Zinc finger, has 1 TFIIS-type Zinc finger.

TFIIS-type

Induces RNA cleavage activity in the RNA polymerase, In its presence, the cleavage activity of the RNA polymerase truncates the RNA back to position +15 in a stepwise manner by releasing mainly dinucleotides from the 3'-end of the nascent RNA, The truncated RNAs are able to continue elongation, Involved in transcriptional proofreading and fidelity, Misincorporation of nucleotides during elongation of transcription leads to arrested elongation complexes which are rescued by TFS-promoted removal of a dinucleotide from the 3'-end, TFS is able to induce a cleavage resynthesis cycle in stalled elongation complexes (resulting from the next missing nucleotide or a reduced incorporation rate of a wrong nucleotide) preventing misincorporation and enabling proofreading in a post-incorporation manner, Pausing of elongation complexes is the main determinant of TFS-induced RNA cleavage

Belongs to the archaeal RpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family


This is Zinc finger protein 703 protein, from Western clawed frog, contains 537 amino acids, has 1 C2H2-type Zinc finger.

Transcriptional corepressor which does not bind directly to DNA and may regulate transcription through recruitment of histone deacetylases to gene promoters, Regulates cell adhesion, migration and proliferation (By similarity), Involved in specification of the lateral neural plate border (NPB) (By similarity), May be required for segmental gene expression during hindbrain development (By similarity)


This is RING finger protein 150 protein, from Zebrafish, contains 419 amino acids, has 1 RING-type; atypical Zinc finger.

RING-type; atypical


This is Zinc finger CCHC-type and RNA-binding motif-containing protein 1 protein, from Bovine, contains 217 amino acids, has 1 CCHC-type Zinc finger.

CCHC-type


This is U1 small nuclear ribonucleoprotein C protein, from Mouse-ear cress, contains 207 amino acids, has 1 Matrin-type Zinc finger.

Matrin-type

Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome, U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing, The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA, Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region


This is RING-H2 finger protein ATL58 protein, from Mouse-ear cress, contains 261 amino acids, has 1 RING-type; atypical Zinc finger.

RING-type; atypical

Belongs to the RING-type zinc finger family, ATL subfamily


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Synechocystis sp. (strain PCC 6803 / Kazusa), contains 326 amino acids, has 1 C4-type Zinc finger.

Component of the acetyl coenzyme A carboxylase (ACC) complex, Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA


This is Formamidopyrimidine-DNA glycosylase protein, from Brucella abortus biovar 1 (strain 9-941), contains 293 amino acids, has 1 FPG-type Zinc finger.

FPG-type

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents, Acts as DNA glycosylase that recognizes and removes damaged bases, Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG), Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand, Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates


This is Chaperone protein DnaJ protein, from Brucella abortus biovar 1 (strain 9-941), contains 377 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Formamidopyrimidine-DNA glycosylase protein, from Salmonella choleraesuis (strain SC-B67), contains 269 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Salmonella choleraesuis (strain SC-B67), contains 304 amino acids, has 1 C4-type Zinc finger.