This is Chaperone protein DnaJ protein, from Shewanella denitrificans (strain OS217 / ATCC BAA-1090 / DSM 15013), contains 377 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Formamidopyrimidine-DNA glycosylase protein, from Shewanella denitrificans (strain OS217 / ATCC BAA-1090 / DSM 15013), contains 271 amino acids, has 1 FPG-type Zinc finger.

FPG-type

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents, Acts as DNA glycosylase that recognizes and removes damaged bases, Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG), Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand, Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates


This is Large ribosomal subunit protein eL24 protein, from Methanococcoides burtonii (strain DSM 6242 / NBRC 107633 / OCM 468 / ACE-M), contains 62 amino acids, has 1 C4-type Zinc finger.

Belongs to the eukaryotic ribosomal protein eL24 family


This is Pregnancy-specific beta-1-glycoprotein 7 protein, from Human, contains 419 amino acids, has 1 Ig-like V-type Immunoglobulin domain, has 3 Ig-like C2-type Immunoglobulin domain.

Ig-like V-type

Ig-like C2-type

Ig-like C2-type

Ig-like C2-type

Belongs to the immunoglobulin superfamily, CEA family


This is Zinc finger protein 154 protein, from Human, contains 437 amino acids, has 1 C2H2-type 1; degenerate Zinc finger, has 1 C2H2-type 2; degenerate Zinc finger, has 10 C2H2-type Zinc finger.

C2H2-type 1; degenerate

C2H2-type 2; degenerate

May be involved in transcriptional regulation

Belongs to the krueppel C2H2-type zinc-finger protein family


This is Formamidopyrimidine-DNA glycosylase protein, from Rhodopseudomonas palustris (strain BisB5), contains 293 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Zinc finger protein 267 protein, from Human, contains 743 amino acids, has 14 C2H2-type Zinc finger, has 1 C2H2-type 2; atypical Zinc finger.

C2H2-type 2; atypical


This is Zinc finger protein 234 protein, from Human, contains 700 amino acids, has 1 C2H2-type 1; degenerate Zinc finger, has 18 C2H2-type Zinc finger.

C2H2-type 1; degenerate


This is Chaperone protein DnaJ protein, from Paraburkholderia xenovorans (strain LB400), contains 380 amino acids, has 1 CR-type Zinc finger.

CR-type

Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion, Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex, GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle, Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding, Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins


This is Formamidopyrimidine-DNA glycosylase protein, from Paraburkholderia xenovorans (strain LB400), contains 276 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Zinc finger protein 846 protein, from Human, contains 533 amino acids, has 1 C2H2-type 1; degenerate Zinc finger, has 1 C2H2-type 2; degenerate Zinc finger, has 11 C2H2-type Zinc finger, has 1 C2H2-type 14; degenerate Zinc finger.

C2H2-type 1; degenerate

C2H2-type 2; degenerate

C2H2-type 14; degenerate


This is Transcription elongation factor A protein 2 protein, from Bovine, contains 300 amino acids, has 1 TFIIS-type Zinc finger.

TFIIS-type

Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites, The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes, Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus (By similarity)


This is Leucine-rich repeat and immunoglobulin-like domain containing-NOGO receptor-interacting protein 4 protein, from Mouse, contains 593 amino acids, has 1 Ig-like C2-type Immunoglobulin domain.

Ig-like C2-type


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic protein, from White poplar, contains 498 amino acids, has 1 C4-type Zinc finger.

Component of the acetyl coenzyme A carboxylase (ACC) complex, Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA


This is Chaperone protein DnaJ protein, from Francisella tularensis subsp. tularensis (strain FSC 198), contains 374 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Chaperone protein DnaJ protein, from Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087), contains 379 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087), contains 282 amino acids, has 1 C4-type Zinc finger.


This is Formamidopyrimidine-DNA glycosylase protein, from Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087), contains 270 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Chaperone protein DnaJ protein, from Erythrobacter sp. (strain OCh 114), contains 384 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Formamidopyrimidine-DNA glycosylase protein, from Erythrobacter sp. (strain OCh 114), contains 283 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is U1 small nuclear ribonucleoprotein C protein, from Yellowfever mosquito, contains 154 amino acids, has 1 Matrin-type Zinc finger.

Matrin-type

Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome, U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing, The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA, Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region

Belongs to the U1 small nuclear ribonucleoprotein C family


This is Nuclear hormone receptor family member nhr-47 protein, from Caenorhabditis elegans, contains 579 amino acids, has 2 NR C4-type Zinc finger.

NR C4-type

NR C4-type

Belongs to the nuclear hormone receptor family


This is Suppressor of presenilin protein 3 protein, from Caenorhabditis elegans, contains 684 amino acids, has 7 C2H2-type Zinc finger.

Probable transcriptional regulator, which participates in the transcriptional repression of the presenilin protein hop-1


This is Nuclear hormone receptor family member nhr-35 protein, from Caenorhabditis elegans, contains 542 amino acids, has 2 NR C4-type Zinc finger.

NR C4-type

NR C4-type


This is Nuclear hormone receptor family member nhr-28 protein, from Caenorhabditis elegans, contains 437 amino acids, has 2 NR C4-type Zinc finger.

NR C4-type

NR C4-type


This is N-chimaerin protein, from Bovine, contains 334 amino acids, has 1 Phorbol-ester/DAG-type Zinc finger.

Phorbol-ester/DAG-type

GTPase-activating protein for p21-rac and a phorbol ester receptor, Involved in the assembly of neuronal locomotor circuits as a direct effector of EPHA4 in axon guidance (By similarity)


This is Target of EGR1 protein 1 protein, from Bovine, contains 524 amino acids, has 1 C3H1-type Zinc finger.

Inhibits cell growth rate and cell cycle, Induces CDKN1A expression as well as TGF-beta expression, Mediates the inhibitory growth effect of EGR1, Involved in the maturation of snRNAs and snRNA 3'-tail processing


This is Zinc finger protein 691 protein, from Bovine, contains 282 amino acids, has 7 C2H2-type Zinc finger.


This is Zinc finger CCCH-type with G patch domain-containing protein protein, from Bovine, contains 513 amino acids, has 1 C3H1-type Zinc finger.

Transcription repressor that specifically binds the 5'-GGAG[GA]A[GA]A-3' consensus sequence, Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters, Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration, Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor (By similarity)


This is ADP-ribosylation factor GTPase-activating protein 3 protein, from Bovine, contains 517 amino acids, has 1 C4-type Zinc finger.

GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1) (PubMed:1910037), Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes (By similarity)


This is Disorganized muscle protein 1 protein, from Caenorhabditis elegans, contains 640 amino acids, has 3 Ig-like C2-type Immunoglobulin domain.

Ig-like C2-type

Ig-like C2-type

Ig-like C2-type

Stabilizes the attachment of the myofilament lattice to the muscle cell membrane, Isoform b is sufficient for wild-type function


This is Chaperone protein DnaJ protein, from Peptoclostridium difficile, contains 384 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Peptoclostridium difficile, contains 284 amino acids, has 1 C4-type Zinc finger.


This is WD repeat and FYVE domain-containing protein 2 protein, from Caenorhabditis elegans, contains 415 amino acids, has 1 FYVE-type Zinc finger.

FYVE-type


This is Chaperone protein DnaJ protein, from Haloquadratum walsbyi (strain DSM 16790 / HBSQ001), contains 387 amino acids, has 1 CR-type Zinc finger.

CR-type


This is mRNA export factor ICP27 homolog protein, from EIHV-1, contains 659 amino acids, has 1 CHC2-type Zinc finger.

Immediate early (EI) protein that plays many roles during productive infection including regulation of viral gene expression and nuclear export of intronless viral RNAs

Belongs to the HHV-1 ICP27 protein family


This is Krueppel-like factor 14 protein, from Mouse, contains 325 amino acids, has 3 C2H2-type Zinc finger.

Belongs to the Sp1 C2H2-type zinc-finger protein family


This is Alpha-1B-glycoprotein protein, from Mouse, contains 512 amino acids, has 5 Ig-like V-type Immunoglobulin domain.

Ig-like V-type

Ig-like V-type

Ig-like V-type

Ig-like V-type

Ig-like V-type


This is Zinc finger Ran-binding domain-containing protein 2 protein, from Pig, contains 328 amino acids, has 2 RanBP2-type Zinc finger.

Splice factor required for alternative splicing of TRA2B/SFRS10 transcripts, May interfere with constitutive 5'-splice site selection (By similarity)


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129 / PRD-1), contains 257 amino acids, has 1 C4-type Zinc finger.


This is Formamidopyrimidine-DNA glycosylase protein, from Mycobacterium sp. (strain MCS), contains 296 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Burkholderia orbicola (strain AU 1054), contains 290 amino acids, has 1 C4-type Zinc finger.


This is Formamidopyrimidine-DNA glycosylase protein, from Burkholderia orbicola (strain AU 1054), contains 275 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Chaperone protein DnaJ protein, from Burkholderia orbicola (strain AU 1054), contains 378 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Chaperone protein DnaJ protein, from Yersinia pestis bv. Antiqua (strain Antiqua), contains 379 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Formamidopyrimidine-DNA glycosylase protein, from Yersinia pestis bv. Antiqua (strain Antiqua), contains 269 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Yersinia pestis bv. Antiqua (strain Antiqua), contains 304 amino acids, has 1 C4-type Zinc finger.


This is Formamidopyrimidine-DNA glycosylase protein, from Yersinia pestis bv. Antiqua (strain Nepal516), contains 269 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Yersinia pestis bv. Antiqua (strain Nepal516), contains 304 amino acids, has 1 C4-type Zinc finger.


This is Chaperone protein DnaJ protein, from Yersinia pestis bv. Antiqua (strain Nepal516), contains 379 amino acids, has 1 CR-type Zinc finger.

CR-type


This is PAN2-PAN3 deadenylation complex subunit PAN3 protein, from Valley fever fungus, contains 657 amino acids, has 1 C3H1-type Zinc finger.

Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover, PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1, PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex, Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenylation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1, May also be involved in post-transcriptional maturation of mRNA poly(A) tails, PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and with PAB1

Belongs to the protein kinase superfamily, PAN3 family


This is Formamidopyrimidine-DNA glycosylase protein, from Lactobacillus delbrueckii subsp. bulgaricus (strain ATCC 11842 / DSM 20081 / BCRC 10696 / JCM 1002 / NBRC 13953 / NCIMB 11778 / NCTC 12712 / WDCM 00102 / Lb 14), contains 273 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Chaperone protein DnaJ protein, from Lactobacillus delbrueckii subsp. bulgaricus (strain ATCC 11842 / DSM 20081 / BCRC 10696 / JCM 1002 / NBRC 13953 / NCIMB 11778 / NCTC 12712 / WDCM 00102 / Lb 14), contains 378 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Lactobacillus delbrueckii subsp. bulgaricus (strain ATCC 11842 / DSM 20081 / BCRC 10696 / JCM 1002 / NBRC 13953 / NCIMB 11778 / NCTC 12712 / WDCM 00102 / Lb 14), contains 282 amino acids, has 1 C4-type Zinc finger.


This is Formamidopyrimidine-DNA glycosylase protein, from Silicibacter sp., contains 283 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Chaperone protein DnaJ protein, from Silicibacter sp., contains 385 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Formamidopyrimidine-DNA glycosylase protein, from Sphingomonas alaskensis, contains 270 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Methylobacillus flagellatus (strain KT / ATCC 51484 / DSM 6875), contains 289 amino acids, has 1 C4-type Zinc finger.


This is Chaperone protein DnaJ protein, from Methylobacillus flagellatus (strain KT / ATCC 51484 / DSM 6875), contains 373 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Formamidopyrimidine-DNA glycosylase protein, from Methylobacillus flagellatus (strain KT / ATCC 51484 / DSM 6875), contains 279 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is mRNA export factor ICP27 homolog protein, from HHV-4, contains 479 amino acids, has 1 CHC2-type Zinc finger.

Promotes the nuclear export of a subset of early and late viral mRNAs by interacting with mRNAs and cellular export proteins, Additionally may prevent the establishment of cellular antiviral state, by acting as an alternative splicing factor for cellular RNAs such as STAT1, resulting in a STAT1 mRNA incapable of producing the STAT1alpha isoform


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Pseudomonas entomophila (strain L48), contains 297 amino acids, has 1 C4-type Zinc finger.


This is Chaperone protein DnaJ protein, from Pseudomonas entomophila (strain L48), contains 375 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Formamidopyrimidine-DNA glycosylase protein, from Pseudomonas entomophila (strain L48), contains 270 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Streptococcus pyogenes serotype M4 (strain MGAS10750), contains 288 amino acids, has 1 C4-type Zinc finger.


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Streptococcus pyogenes serotype M12 (strain MGAS2096), contains 288 amino acids, has 1 C4-type Zinc finger.


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Streptococcus pyogenes serotype M2 (strain MGAS10270), contains 288 amino acids, has 1 C4-type Zinc finger.


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Streptococcus pyogenes serotype M12 (strain MGAS9429), contains 288 amino acids, has 1 C4-type Zinc finger.


This is THAP domain-containing protein 1 protein, from Zebrafish, contains 225 amino acids, has 1 THAP-type Zinc finger.

THAP-type

DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression, Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes (By similarity)


This is TATA box-binding protein-associated factor RNA polymerase I subunit B protein, from Bovine, contains 590 amino acids, has 1 RRN7-type Zinc finger.

Component of RNA polymerase I core factor complex that acts as a GTF2B/TFIIB-like factor and plays a key role in multiple steps during transcription initiation such as pre-initiation complex (PIC) assembly and postpolymerase recruitment events in polymerase I (Pol I) transcription, Binds rDNA promoters and plays a role in Pol I recruitment as a component of the SL1/TIF-IB complex and, possibly, directly through its interaction with RRN3 (By similarity)


This is Lethal(3)malignant brain tumor-like protein 2 protein, from Bovine, contains 706 amino acids, has 1 FCS-type Zinc finger.

FCS-type

Putative Polycomb group (PcG) protein, PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility, Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis, Binds to monomethylated and dimethylated 'Lys-20' on histone H4, Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27' (By similarity)


This is U1 small nuclear ribonucleoprotein C protein, from Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987), contains 216 amino acids, has 1 Matrin-type Zinc finger.

Matrin-type


This is Endoplasmic reticulum junction formation protein lunapark-B protein, from Japanese pufferfish, contains 358 amino acids, has 1 C4-type; plays a role in ER morphology Zinc finger.

C4-type; plays a role in ER morphology

Endoplasmic reticulum (ER)-shaping membrane protein that plays a role in determining ER morphology, Involved in the stabilization of nascent three-way ER tubular junctions within the ER network, May also play a role as a curvature-stabilizing protein within three-way ER tubular junction network (By similarity)


This is Endoplasmic reticulum junction formation protein lunapark-A protein, from Japanese pufferfish, contains 348 amino acids, has 1 C4-type; plays a role in ER morphology Zinc finger.

C4-type; plays a role in ER morphology


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic protein, from Common sunflower, contains 480 amino acids, has 1 C4-type Zinc finger.


This is GATA zinc finger domain-containing protein 1 protein, from Zebrafish, contains 242 amino acids, has 1 GATA-type Zinc finger.

GATA-type

Component of some chromatin complex recruited to chromatin sites methylated 'Lys-4' of histone H3 (H3K4me), with a preference for trimethylated form (H3K4me3)


This is Zinc finger and BTB domain-containing protein 18 protein, from Zebrafish, contains 537 amino acids, has 4 C2H2-type Zinc finger.

Transcriptional repressor that plays a role in various developmental processes, Specifically binds the consensus DNA sequence 5'-[AC]ACATCTG[GT][AC]-3' which contains the E box core, and acts by recruiting chromatin remodeling multiprotein complexes (By similarity)

Belongs to the krueppel C2H2-type zinc-finger protein family, ZBTB18 subfamily


This is Chaperone protein DnaJ protein, from Ralstonia metallidurans, contains 379 amino acids, has 1 CR-type Zinc finger.

CR-type

Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion, Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex, GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle, Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding, Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins


This is Formamidopyrimidine-DNA glycosylase protein, from Ralstonia metallidurans, contains 297 amino acids, has 1 FPG-type Zinc finger.

FPG-type

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents, Acts as DNA glycosylase that recognizes and removes damaged bases, Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG), Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand, Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Baumannia cicadellinicola subsp. Homalodisca coagulata, contains 295 amino acids, has 1 C4-type Zinc finger.

Component of the acetyl coenzyme A carboxylase (ACC) complex, Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA


This is Formamidopyrimidine-DNA glycosylase protein, from Baumannia cicadellinicola subsp. Homalodisca coagulata, contains 269 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Zinc finger protein 143 protein, from Zebrafish, contains 623 amino acids, has 7 C2H2-type Zinc finger.

Transcriptional activator, Activates the gene for selenocysteine tRNA (tRNAsec), Binds to the activator element (AE) motif of the selenocysteine tRNA gene promoter (By similarity)

Belongs to the GLI C2H2-type zinc-finger protein family


This is Zinc finger protein 397 protein, from Bovine, contains 534 amino acids, has 9 C2H2-type Zinc finger.


This is RAS guanyl-releasing protein 4 protein, from Bovine, contains 673 amino acids, has 1 Phorbol-ester/DAG-type Zinc finger.

Phorbol-ester/DAG-type

Functions as a cation- and diacylglycerol (DAG)-regulated nucleotide exchange factor activating Ras through the exchange of bound GDP for GTP, May function in mast cells differentiation (By similarity)


This is Zinc finger protein 22 protein, from Bovine, contains 225 amino acids, has 5 C2H2-type Zinc finger.

Binds DNA through the consensus sequence 5'-CAATG-3', May be involved in transcriptional regulation and may play a role in tooth formation (By similarity)


This is E3 ubiquitin-protein ligase KCMF1 protein, from Bovine, contains 381 amino acids, has 1 ZZ-type Zinc finger, has 1 C2H2-type Zinc finger.

ZZ-type

Has intrinsic E3 ubiquitin ligase activity and promotes ubiquitination


This is Formamidopyrimidine-DNA glycosylase protein, from Rhizobium leguminosarum bv. viciae (strain 3841), contains 296 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Chaperone protein DnaJ protein, from Rhizobium leguminosarum bv. viciae (strain 3841), contains 375 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Uncharacterized RING finger membrane protein C15C4.06c protein, from Fission yeast, contains 556 amino acids, has 1 RING-type; atypical Zinc finger.

RING-type; atypical


This is Transcriptional activator VP30 protein, from MARV, contains 281 amino acids, has 1 C3H1-type; atypical Zinc finger.

C3H1-type; atypical

Acts as a transcription anti-termination factor immediately after transcription initiation, but does not affect transcription elongation, This function has been found to be dependent on the formation of an RNA secondary structure at the transcription start site of the first gene (By similarity)

Belongs to the filoviridae transcriptional activator VP30 family


C3H1-type; atypical


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Psychrobacter cryohalolentis (strain ATCC BAA-1226 / DSM 17306 / VKM B-2378 / K5), contains 317 amino acids, has 1 C4-type Zinc finger.


This is Chaperone protein DnaJ protein, from Psychrobacter cryohalolentis (strain ATCC BAA-1226 / DSM 17306 / VKM B-2378 / K5), contains 378 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Chaperone protein DnaJ protein, from Chromohalobacter salexigens (strain ATCC BAA-138 / DSM 3043 / CIP 106854 / NCIMB 13768 / 1H11), contains 381 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Chromohalobacter salexigens (strain ATCC BAA-138 / DSM 3043 / CIP 106854 / NCIMB 13768 / 1H11), contains 310 amino acids, has 1 C4-type Zinc finger.


This is Formamidopyrimidine-DNA glycosylase protein, from Escherichia coli (strain UTI89 / UPEC), contains 269 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Escherichia coli (strain UTI89 / UPEC), contains 304 amino acids, has 1 C4-type Zinc finger.


This is Endonuclease 8 protein, from Escherichia coli (strain UTI89 / UPEC), contains 263 amino acids, has 1 FPG-type Zinc finger.

FPG-type

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents, Acts as DNA glycosylase that recognizes and removes damaged bases, Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine, Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand, Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates


This is Chaperone protein DnaJ protein, from Escherichia coli (strain UTI89 / UPEC), contains 376 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Chaperone protein DnaJ protein, from Rickettsia bellii (strain RML369-C), contains 376 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Primosomal protein N' protein, from Rickettsia bellii (strain RML369-C), contains 648 amino acids, has 2 C4-type Zinc finger.

Involved in the restart of stalled replication forks, Recognizes and binds the arrested nascent DNA chain at stalled replication forks, It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA

Belongs to the helicase family, PriA subfamily


This is DNA repair protein RadA protein, from Rickettsia bellii (strain RML369-C), contains 448 amino acids, has 1 C4-type Zinc finger.

DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks, Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster, Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB, Does not have RecA's homology-searching function

Belongs to the RecA family, RadA subfamily


This is Formamidopyrimidine-DNA glycosylase protein, from Rickettsia bellii (strain RML369-C), contains 273 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is UvrABC system protein A protein, from Rickettsia bellii (strain RML369-C), contains 953 amino acids, has 1 C4-type Zinc finger.

The UvrABC repair system catalyzes the recognition and processing of DNA lesions, UvrA is an ATPase and a DNA-binding protein, A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities, When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate

Belongs to the ABC transporter superfamily, UvrA family


This is DNA primase protein, from Rickettsia bellii (strain RML369-C), contains 599 amino acids, has 1 CHC2-type Zinc finger.

RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication


This is THAP domain-containing protein 5 protein, from Bovine, contains 394 amino acids, has 1 THAP-type Zinc finger.

THAP-type

Has sequence-specific DNA-binding activity and can function as transcriptional repressor (in vitro), May be a regulator of cell cycle: THAP5 overexpression in human cell lines causes cell cycle arrest at G2/M phase


This is Zinc finger CCCH domain-containing protein 15 protein, from Bovine, contains 426 amino acids, has 2 C3H1-type Zinc finger.

Protects DRG1 from proteolytic degradation


This is DNA-directed RNA polymerase I subunit RPA12 protein, from Bovine, contains 123 amino acids, has 1 C4-type Zinc finger, has 1 TFIIS-type Zinc finger.

TFIIS-type

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates, Component of RNA polymerase I which synthesizes ribosomal RNA precursors

Belongs to the archaeal RpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family


This is Formamidopyrimidine-DNA glycosylase protein, from Lactobacillus salivarius, contains 276 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Lactobacillus salivarius, contains 283 amino acids, has 1 C4-type Zinc finger.


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic protein, from Susabi-nori, contains 288 amino acids, has 1 C4-type Zinc finger.


This is ZAR1-like protein protein, from Bovine, contains 318 amino acids, has 1 3CxxC-type Zinc finger.

mRNA-binding protein required for maternal mRNA storage, translation and degradation during oocyte maturation (By similarity), Probably promotes formation of some phase-separated membraneless compartment that stores maternal mRNAs in oocytes: acts by undergoing liquid-liquid phase separation upon binding to maternal mRNAs (By similarity), Binds to the 3'-UTR of maternal mRNAs, inhibiting their translation (By similarity)

Cytoplasm, Cytoplasmic ribonucleoprotein granule


This is E3 ubiquitin ligase TRIM40 protein, from Chimpanzee, contains 229 amino acids, has 1 RING-type Zinc finger, has 1 B box-type Zinc finger.

RING-type

B box-type

E3 ubiquitin-protein ligase that plays a role in the limitation of the innate immune response, Mediates inhibition of the RLR signaling pathway by ubiquitinating RIGI and IFIH1 receptors, leading to their proteasomal degradation, Promotes also the neddylation of IKBKG/NEMO, stabilizing NFKBIA, and thereby inhibiting of NF-kappa-B nuclear translocation and activation


This is DNA-directed RNA polymerase I subunit RPA12 protein, from Chimpanzee, contains 126 amino acids, has 1 C4-type Zinc finger, has 1 TFIIS-type Zinc finger.

TFIIS-type


This is Basonuclin zinc finger protein homolog protein, from Caenorhabditis elegans, contains 205 amino acids, has 2 C2H2-type Zinc finger.

Probable transcription factor (PubMed:28056346), Involved in motor neuron fate determination and maintenance, acting as a transcriptional repressor to counteract gene activation by transcription factor unc-3 in a subset of motor neurons (PubMed:28056346), Required throughout development to repress transcription by unc-3, probably acting by binding to specific promoter elements (PubMed:28056346), Represses expression of DA and DB motor neuron-specific effector genes, such as unc-129 and unc-53, in VA and VB motor neurons (PubMed:28056346)


This is Zinc finger protein zfp-2 protein, from Caenorhabditis elegans, contains 422 amino acids, has 7 C2H2-type Zinc finger.

Probable zinc finger transcription factor that acts as a transcriptional repressor, Acts redundantly with the transcriptional repressor lin-35 to control the development of somatic gonad lineages, May, in addition, suppress sensitivity to RNAi


This is Zinc finger protein ztf-7 protein, from Caenorhabditis elegans, contains 614 amino acids, has 2 C2H2-type Zinc finger.


This is Nuclear hormone receptor family member nhr-7 protein, from Caenorhabditis elegans, contains 536 amino acids, has 2 NR C4-type Zinc finger.

NR C4-type

NR C4-type


This is Nuclear hormone receptor family member nhr-12 protein, from Caenorhabditis elegans, contains 453 amino acids, has 2 NR C4-type Zinc finger.

NR C4-type

NR C4-type


This is Nuclear hormone receptor family member nhr-209 protein, from Caenorhabditis elegans, contains 418 amino acids, has 2 NR C4-type Zinc finger.

NR C4-type

NR C4-type

Transcriptional regulator (By similarity), Plays a role in modulation of lifespan and immunity (PubMed:29748542)


This is Formamidopyrimidine-DNA glycosylase protein, from Rhodopseudomonas palustris (strain BisB18), contains 293 amino acids, has 1 FPG-type Zinc finger.

FPG-type

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents, Acts as DNA glycosylase that recognizes and removes damaged bases, Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG), Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand, Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates


This is Chaperone protein DnaJ protein, from Rhodopseudomonas palustris (strain BisB18), contains 379 amino acids, has 1 CR-type Zinc finger.

CR-type

Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion, Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex, GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle, Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding, Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins


This is Formamidopyrimidine-DNA glycosylase protein, from Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024), contains 271 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Chaperone protein DnaJ protein, from Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024), contains 374 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Formamidopyrimidine-DNA glycosylase protein, from Rhodoferax ferrireducens, contains 271 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Nuclear hormone receptor family member nhr-44 protein, from Caenorhabditis elegans, contains 428 amino acids, has 2 NR C4-type Zinc finger.

NR C4-type

NR C4-type


This is Specificity protein transcription factor 2 protein, from Caenorhabditis elegans, contains 166 amino acids, has 3 C2H2-type Zinc finger.

Transcription factor (By similarity), Probably acts downstream of the Wnt signaling pathway (PubMed:24569038)


This is Nuclear hormone receptor family member nhr-11 protein, from Caenorhabditis elegans, contains 459 amino acids, has 2 NR C4-type Zinc finger.

NR C4-type

NR C4-type


This is Nuclear hormone receptor family member nhr-9 protein, from Caenorhabditis elegans, contains 332 amino acids, has 2 NR C4-type Zinc finger.

NR C4-type

NR C4-type


This is Replication factor A 51 kDa subunit protein, from Crithidia fasciculata, contains 467 amino acids, has 1 C4-type Zinc finger.

As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress, It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism, Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage

Belongs to the replication factor A protein 1 family


This is Protein ref(2)P protein, from Fruit fly, contains 599 amino acids, has 1 ZZ-type Zinc finger.

ZZ-type

Required for selective autophagy activation by ubiquitinated proteins, Implicated in sigma rhabdovirus multiplication and necessary for male fertility, Involved in activating transcription of Drs


This is Zygotic gap protein knirps protein, from Fruit fly, contains 481 amino acids, has 2 NR C4-type Zinc finger.

NR C4-type

NR C4-type

Transcriptional repressor, Binds to multiple sites in the eve stripe 3 enhancer element, Plays an essential role in the segmentation process both by refining the expression patterns of gap genes and by establishing pair-rules stripes of gene expression (By similarity)

Belongs to the nuclear hormone receptor family, NR0 subfamily


This is Chaperone protein DnaJ protein, from Desulfitobacterium hafniense (strain Y51), contains 377 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Formamidopyrimidine-DNA glycosylase protein, from Desulfitobacterium hafniense (strain Y51), contains 273 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Desulfitobacterium hafniense (strain Y51), contains 304 amino acids, has 1 C4-type Zinc finger.

Component of the acetyl coenzyme A carboxylase (ACC) complex, Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA


This is Protein kinase C protein, from Painted sea urchin, contains 658 amino acids, has 2 Phorbol-ester/DAG-type Zinc finger.

Phorbol-ester/DAG-type

Phorbol-ester/DAG-type

PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins, PKC also serves as the receptor for phorbol esters, a class of tumor promoters (By similarity)

Belongs to the protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily


This is Chaperone protein DnaJ protein, from Chlamydophila felis, contains 391 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Protein hunchback protein, from Tobacco hawkmoth, contains 327 amino acids, has 5 C2H2-type Zinc finger.

Gap class segmentation protein that controls development of head structures

Belongs to the hunchback C2H2-type zinc-finger protein family


This is Lachesin protein, from American grasshopper, contains 349 amino acids, has 1 Ig-like V-type Immunoglobulin domain, has 2 Ig-like C2-type Immunoglobulin domain.

Ig-like V-type

Ig-like C2-type

Ig-like C2-type

May play a role in early neuronal differentiation and axon outgrowth


This is Nuclear hormone receptor family member nhr-16 protein, from Caenorhabditis elegans, contains 388 amino acids, has 2 NR C4-type Zinc finger.

NR C4-type

NR C4-type


This is RING finger protein Z protein, from IPPYV, contains 101 amino acids, has 1 RING-type; atypical Zinc finger.

RING-type; atypical

Plays a crucial role in virion assembly and budding, Expressed late in the virus life cycle, it acts as an inhibitor of viral transcription and RNA synthesis by interacting with the viral polymerase L, Presumably recruits the NP encapsidated genome to cellular membranes at budding sites via direct interaction with NP, Plays critical roles in the final steps of viral release by interacting with host TSG101, a member of the vacuolar protein-sorting pathway and using other cellular host proteins involved in vesicle formation pathway, The budding of the virus progeny occurs after association of protein Z with the viral glycoprotein complex SSP-GP1-GP2 at the cell periphery, step that requires myristoylation of protein Z, Also selectively represses protein production by associating with host eIF4E

Belongs to the arenaviridae Z protein family


This is RING finger protein Z protein, from MOBV, contains 99 amino acids, has 1 RING-type; atypical Zinc finger.

RING-type; atypical


This is RNA-binding protein FUS protein, from Bovine, contains 513 amino acids, has 1 RanBP2-type Zinc finger.

DNA/RNA-binding protein that plays a role in various cellular processes such as transcription regulation, RNA splicing, RNA transport, DNA repair and damage response, Binds to nascent pre-mRNAs and acts as a molecular mediator between RNA polymerase II and U1 small nuclear ribonucleoprotein thereby coupling transcription and splicing, Binds also its own pre-mRNA and autoregulates its expression; this autoregulation mechanism is mediated by non-sense-mediated decay, Plays a role in DNA repair mechanisms by promoting D-loop formation and homologous recombination during DNA double-strand break repair (By similarity), In neuronal cells, plays crucial roles in dendritic spine formation and stability, RNA transport, mRNA stability and synaptic homeostasis (By similarity)


This is Ras GTPase-activating protein 3 protein, from Bovine, contains 834 amino acids, has 1 Btk-type Zinc finger.

Btk-type

Inhibitory regulator of the Ras-cyclic AMP pathway, May bind inositol tetrakisphosphate (IP4)


This is T-cell surface glycoprotein CD3 epsilon chain protein, from Bovine, contains 192 amino acids, has 1 Ig-like Immunoglobulin domain.

Ig-like

Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response, When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z, All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain, Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of downstream signaling pathways, In addition of this role of signal transduction in T-cell activation, CD3E plays an essential role in correct T-cell development, Initiates the TCR-CD3 complex assembly by forming the two heterodimers CD3D/CD3E and CD3G/CD3E, Participates also in internalization and cell surface down-regulation of TCR-CD3 complexes via endocytosis sequences present in CD3E cytosolic region


This is Intercellular adhesion molecule 3 protein, from Bovine, contains 544 amino acids, has 5 Ig-like C2-type Immunoglobulin domain.

Ig-like C2-type

Ig-like C2-type

Ig-like C2-type

Ig-like C2-type

Ig-like C2-type

ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2), ICAM3 is also a ligand for integrin alpha-D/beta-2, In association with integrin alpha-L/beta-2, contributes to apoptotic neutrophil phagocytosis by macrophages

Belongs to the immunoglobulin superfamily, ICAM family


This is Interleukin-12 subunit beta protein, from Red deer, contains 327 amino acids, has 1 Ig-like C2-type Immunoglobulin domain.

Ig-like C2-type

Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity, IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues, IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of pro-inflammatory cytokines, IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis (By similarity)


This is Vascular cell adhesion protein 1 protein, from Dog, contains 739 amino acids, has 7 Ig-like C2-type Immunoglobulin domain.

Ig-like C2-type

Ig-like C2-type

Ig-like C2-type

Ig-like C2-type

Ig-like C2-type

Ig-like C2-type

Ig-like C2-type

Cell adhesion glycoprotein predominantly expressed on the surface of endothelial cells that plays an important role in immune surveillance and inflammation, Acts as a major regulator of leukocyte adhesion to the endothelium through interaction with different types of integrins, During inflammatory responses, binds ligands on the surface of activated endothelial cells to initiate the activation of calcium channels and the plasma membrane-associated small GTPase RAC1 leading to leukocyte transendothelial migration, Serves also as a quality-control checkpoint for entry into bone marrow by providing a 'don't-eat-me' stamping in the context of major histocompatibility complex (MHC) class-I presentation


This is Interleukin-12 subunit beta protein, from Dog, contains 329 amino acids, has 1 Ig-like C2-type Immunoglobulin domain.

Ig-like C2-type


This is Hyaluronan and proteoglycan link protein 1 protein, from Horse, contains 354 amino acids, has 1 Ig-like V-type Immunoglobulin domain.

Ig-like V-type

Stabilizes the aggregates of proteoglycan monomers with hyaluronic acid in the extracellular cartilage matrix

Secreted, extracellular space, extracellular matrix


This is T-cell surface glycoprotein CD1b-1 protein, from Sheep, contains 333 amino acids, has 1 Ig-like Immunoglobulin domain.

Ig-like

Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells


This is Progesterone receptor protein, from Sheep, contains 377 amino acids, has 2 NR C4-type Zinc finger.

NR C4-type

NR C4-type

The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues, Transcriptional activator of several progesteron-dependent promoters in a variety of cell types, Involved in activation of SRC-dependent MAPK signaling on hormone stimulation

Belongs to the nuclear hormone receptor family, NR3 subfamily


This is Aggrecan core protein protein, from Rabbit, contains 394 amino acids, has 1 Ig-like V-type Immunoglobulin domain.

Ig-like V-type

This proteoglycan is a major component of extracellular matrix of cartilagenous tissues, A major function of this protein is to resist compression in cartilage, It binds avidly to hyaluronic acid via an N-terminal globular region, May play a regulatory role in the matrix assembly of the cartilage

Belongs to the aggrecan/versican proteoglycan family


This is Intercellular adhesion molecule 1 protein, from Chimpanzee, contains 532 amino acids, has 5 Ig-like C2-type Immunoglobulin domain.

Ig-like C2-type

Ig-like C2-type

Ig-like C2-type

Ig-like C2-type

Ig-like C2-type

ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2), During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation (By similarity)


This is Nuclear receptor subfamily 2 group C member 1 protein, from Western clawed frog, contains 636 amino acids, has 2 NR C4-type Zinc finger.

NR C4-type

NR C4-type

Orphan nuclear receptor, Binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism, Primarily repressor of a broad range of genes, Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences (By similarity)

Belongs to the nuclear hormone receptor family, NR2 subfamily


This is ADP-ribosylation factor GTPase-activating protein 2 protein, from Western clawed frog, contains 526 amino acids, has 1 C4-type Zinc finger.

GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1), Implicated in coatomer-mediated protein transport between the Golgi complex and the endoplasmic reticulum, Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes (By similarity)


This is E3 ubiquitin-protein ligase RNF170 protein, from Western clawed frog, contains 257 amino acids, has 1 RING-type Zinc finger.

RING-type

E3 ubiquitin-protein ligase that plays an essential role in stimulus-induced inositol 1,4,5-trisphosphate receptor (ITPR) ubiquitination and degradation via the endoplasmic reticulum-associated degradation (ERAD) pathway, Also involved in ITPR turnover in resting cells


This is DBIRD complex subunit ZNF326 protein, from Western clawed frog, contains 489 amino acids, has 2 C2H2 AKAP95-type Zinc finger.

C2H2 AKAP95-type

C2H2 AKAP95-type

Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing


This is Protein DBF4 homolog A protein, from Western clawed frog, contains 663 amino acids, has 1 DBF4-type Zinc finger.

Regulatory subunit for cdc7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation, Not required during the initiation of DNA replication in egg and during early embryonic development but is required later throughout development, The complex cdc7-dbf4a phosphorylates mcm2 subunit (By similarity)


This is E3 ubiquitin-protein ligase RNFT1 protein, from Western clawed frog, contains 416 amino acids, has 1 RING-type Zinc finger.

RING-type

E3 ubiquitin-protein ligase that acts in the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway, which targets misfolded proteins that accumulate in the endoplasmic reticulum (ER) for ubiquitination and subsequent proteasome-mediated degradation, Protects cells from ER stress-induced apoptosis


This is Histone deacetylase complex subunit SAP30L protein, from Western clawed frog, contains 181 amino acids, has 1 Atypical Zinc finger.

Atypical

Functions as transcription repressor, probably via its interaction with histone deacetylase complexes, Involved in the functional recruitment of the class 1 Sin3-histone deacetylase complex (HDAC) to the nucleolus, Binds DNA, apparently without sequence-specificity, and bends bound double-stranded DNA, Binds phosphoinositol phosphates (phosphoinositol 3-phosphate, phosphoinositol 4-phosphate and phosphoinositol 5-phosphate) via the same basic sequence motif that mediates DNA binding and nuclear import


This is Endoplasmic reticulum junction formation protein lunapark protein, from Western clawed frog, contains 423 amino acids, has 1 C4-type; plays a role in ER morphology Zinc finger.

C4-type; plays a role in ER morphology

Endoplasmic reticulum (ER)-shaping membrane protein that plays a role in determining ER morphology, Involved in the stabilization of nascent three-way ER tubular junctions within the ER network, May also play a role as a curvature-stabilizing protein within three-way ER tubular junction network (By similarity)


This is Formamidopyrimidine-DNA glycosylase protein, from Jannaschia sp. (strain CCS1), contains 283 amino acids, has 1 FPG-type Zinc finger.

FPG-type

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents, Acts as DNA glycosylase that recognizes and removes damaged bases, Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG), Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand, Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates


This is Chaperone protein DnaJ protein, from Jannaschia sp. (strain CCS1), contains 385 amino acids, has 1 CR-type Zinc finger.

CR-type

Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion, Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex, GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle, Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding, Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Jannaschia sp. (strain CCS1), contains 318 amino acids, has 1 C4-type Zinc finger.

Component of the acetyl coenzyme A carboxylase (ACC) complex, Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA


This is Mineralocorticoid receptor protein, from Common tree shrew, contains 977 amino acids, has 2 NR C4-type Zinc finger.

NR C4-type

NR C4-type

Receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol, Binds to mineralocorticoid response elements (MRE) and transactivates target genes, The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels (By similarity)


This is Transcription factor Ken protein, from Fruit fly, contains 569 amino acids, has 3 C2H2-type Zinc finger.

Transcription factor required for terminalia development, Negative regulator of the JAK/STAT pathway: represses JAK/STAT-dependent expression of ventral veins lacking (vvl) in the posterior spiracles (By similarity)


This is Splicing factor U2AF 35 kDa subunit protein, from Pig, contains 82 amino acids, has 1 C3H1-type Zinc finger.

Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection, Recruits U2 snRNP to the branch point, Directly mediates interactions between U2AF2 and proteins bound to the enhancers and thus may function as a bridge between U2AF2 and the enhancer complex to recruit it to the adjacent intron (By similarity)

Belongs to the splicing factor SR family


This is T-cell surface glycoprotein CD1b-2 protein, from Sheep, contains 333 amino acids, has 1 Ig-like Immunoglobulin domain.

Ig-like

Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells


This is U1 small nuclear ribonucleoprotein C protein, from Fruit fly, contains 146 amino acids, has 1 Matrin-type Zinc finger.

Matrin-type

Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome, U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing, The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA, Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region

Belongs to the U1 small nuclear ribonucleoprotein C family


This is Zinc finger protein 574 protein, from Bovine, contains 896 amino acids, has 19 C2H2-type Zinc finger, has 1 C2H2-type 15; degenerate Zinc finger.

C2H2-type 15; degenerate

May be involved in transcriptional regulation

Belongs to the krueppel C2H2-type zinc-finger protein family


This is Transcription elongation factor A protein 1 protein, from Bovine, contains 301 amino acids, has 1 TFIIS-type Zinc finger.

TFIIS-type

Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites, The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes, Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus (By similarity)


This is V-set and immunoglobulin domain-containing protein 1 protein, from Bovine, contains 382 amino acids, has 1 Ig-like V-type Immunoglobulin domain, has 1 Ig-like C2-type Immunoglobulin domain.

Ig-like V-type

Ig-like C2-type


This is Zinc finger protein 2 protein, from Bovine, contains 425 amino acids, has 8 C2H2-type Zinc finger, has 1 C2H2-type 9; degenerate Zinc finger.

C2H2-type 9; degenerate


This is Transcription factor IIIB 50 kDa subunit protein, from Bovine, contains 421 amino acids, has 1 TFIIB-type Zinc finger.

TFIIB-type

General activator of RNA polymerase III transcription, Factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites, Contributes to the regulation of gene expression; functions as activator in the absence of oxidative stress, Down-regulates expression of target genes in response to oxidative stress, Overexpression protects cells against apoptosis in response to oxidative stress


This is Myelin-oligodendrocyte glycoprotein protein, from White-tufted-ear marmoset, contains 245 amino acids, has 1 Ig-like V-type Immunoglobulin domain.

Ig-like V-type

Minor component of the myelin sheath, May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication, Mediates homophilic cell-cell adhesion (By similarity)

Belongs to the immunoglobulin superfamily, BTN/MOG family


This is Chaperone protein DnaJ protein, from Francisella tularensis subsp. holarctica (strain LVS), contains 371 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Green alga, contains 471 amino acids, has 1 C4-type Zinc finger.


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Staphylococcus aureus (strain USA300), contains 285 amino acids, has 1 C4-type Zinc finger.


This is Chaperone protein DnaJ protein, from Staphylococcus aureus (strain USA300), contains 379 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Staphylococcus aureus (strain NCTC 8325 / PS 47), contains 285 amino acids, has 1 C4-type Zinc finger.


This is Chaperone protein DnaJ protein, from Staphylococcus aureus (strain NCTC 8325 / PS 47), contains 379 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Membrane-associated protein TcaA protein, from Staphylococcus aureus (strain NCTC 8325 / PS 47), contains 460 amino acids, has 1 C4-type Zinc finger.

Plays a major role in decreasing resistance to glycopeptide antibiotics


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Novosphingobium aromaticivorans (strain ATCC 700278 / DSM 12444 / CCUG 56034 / CIP 105152 / NBRC 16084 / F199), contains 283 amino acids, has 1 C4-type Zinc finger.


This is Formamidopyrimidine-DNA glycosylase protein, from Novosphingobium aromaticivorans (strain ATCC 700278 / DSM 12444 / CCUG 56034 / CIP 105152 / NBRC 16084 / F199), contains 270 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Chaperone protein DnaJ protein, from Ehrlichia chaffeensis (strain ATCC CRL-10679 / Arkansas), contains 380 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Chaperone protein DnaJ protein, from Anaplasma phagocytophilum (strain HZ), contains 382 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Vacuolar protein sorting-associated protein 27 protein, from Soil fungus, contains 737 amino acids, has 1 FYVE-type; degenerate Zinc finger.

FYVE-type; degenerate

Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane


This is Structure-specific endonuclease subunit SLX1 protein, from Soil fungus, contains 325 amino acids, has 1 SLX1-type Zinc finger.

Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination, Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA


This is PAN2-PAN3 deadenylation complex subunit PAN3 protein, from Soil fungus, contains 648 amino acids, has 1 C3H1-type Zinc finger.

Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover, PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1, PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex, Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenylation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1, May also be involved in post-transcriptional maturation of mRNA poly(A) tails, PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and with PAB1

Belongs to the protein kinase superfamily, PAN3 family


This is Protein FYV10 protein, from Soil fungus, contains 441 amino acids, has 1 RING-Gid-type Zinc finger.

RING-Gid-type

Involved in the proteasome-dependent degradation of fructose-1,6-bisphosphatase


This is Probable E3 ubiquitin-protein ligase RHB1A protein, from Mouse-ear cress, contains 190 amino acids, has 1 RING-type; atypical Zinc finger.

RING-type; atypical

Probable E3 ubiquitin-protein ligase that may possess E3 ubiquitin ligase activity in vitro


This is Formamidopyrimidine-DNA glycosylase protein, from Rhodopseudomonas palustris (strain HaA2), contains 293 amino acids, has 1 FPG-type Zinc finger.

FPG-type

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents, Acts as DNA glycosylase that recognizes and removes damaged bases, Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG), Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand, Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates


This is Chaperone protein DnaJ protein, from Rhodopseudomonas palustris (strain HaA2), contains 379 amino acids, has 1 CR-type Zinc finger.

CR-type

Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion, Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex, GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle, Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding, Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins


This is Chaperone protein DnaJ protein, from Cyanobacteria bacterium Yellowstone B-Prime, contains 394 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Cyanobacteria bacterium Yellowstone B-Prime, contains 314 amino acids, has 1 C4-type Zinc finger.

Component of the acetyl coenzyme A carboxylase (ACC) complex, Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Cyanobacteria bacterium Yellowstone A-Prime, contains 314 amino acids, has 1 C4-type Zinc finger.


This is Chaperone protein DnaJ protein, from Cyanobacteria bacterium Yellowstone A-Prime, contains 394 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Formamidopyrimidine-DNA glycosylase protein, from Rhizobium etli (strain CFN 42 / ATCC 51251), contains 296 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Chaperone protein DnaJ protein, from Rhizobium etli (strain CFN 42 / ATCC 51251), contains 375 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Host transcription reprogramming factor 1 protein, from Rice blast fungus, contains 198 amino acids, has 1 C2H2-type Zinc finger.

Secreted effector that translocates into the nuclei of host cells to reprogram the expression of immunity-associated genes by binding to effector binding elements (EBEs) in rice (PubMed:33203871), Binds the 5'-CAATCTTC-3' EBE of promoters from targeted rice genes and probably recruits a yet to be determined host repressor (PubMed:33203871), Causes ambivalent immunity with increased susceptibility to the hemibiotrophic pathogens Magnaporthe oryzae and Xanthomonas oryzae pv, oryzae, but enhances resistance to Cochliobolus miyabeanus, a necrotrophic pathogen (PubMed:33203871)


This is PAN2-PAN3 deadenylation complex subunit PAN3 protein, from Rice blast fungus, contains 680 amino acids, has 1 C3H1-type Zinc finger.


This is Small ribosomal subunit protein eS27 protein, from Bovine, contains 84 amino acids, has 1 C4-type Zinc finger.

Component of the small ribosomal subunit, The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell, Required for proper rRNA processing and maturation of 18S rRNAs, Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit, During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome

Belongs to the eukaryotic ribosomal protein eS27 family


This is Transcription elongation factor A protein 3 protein, from Bovine, contains 349 amino acids, has 1 TFIIS-type Zinc finger.

TFIIS-type


This is Zinc finger protein 181 protein, from Bovine, contains 570 amino acids, has 11 C2H2-type Zinc finger.


This is Zinc finger CCHC domain-containing protein 7 protein, from Bovine, contains 546 amino acids, has 4 CCHC-type Zinc finger.

CCHC-type

CCHC-type

CCHC-type

CCHC-type


This is WD repeat and FYVE domain-containing protein 1 protein, from Bovine, contains 410 amino acids, has 1 FYVE-type Zinc finger.

FYVE-type

Positively regulates TLR3- and TLR4-mediated signaling pathways by bridging the interaction between TLR3 or TLR4 and TICAM1, Promotes TLR3/4 ligand-induced activation of transcription factors IRF3 and NF-kappa-B, as well as the production of IFN-beta and inflammatory cytokines


This is Calcium-binding and coiled-coil domain-containing protein 1 protein, from Bovine, contains 680 amino acids, has 1 UBZ1-type Zinc finger.

Seems to enhance inorganic pyrophosphatase thus activating phosphogluomutase (PMG), Probably functions as component of the calphoglin complex, which is involved in linking cellular metabolism (phosphate and glucose metabolism) with other core functions including protein synthesis and degradation, calcium signaling and cell growth (By similarity)


This is Tax1-binding protein 1 homolog protein, from Bovine, contains 817 amino acids, has 2 UBZ1-type Zinc finger.

Ubiquitin-binding adapter that participates in inflammatory, antiviral and innate immune processes as well as selective autophagy regulation, Plays a key role in the negative regulation of NF-kappa-B and IRF3 signalings by acting as an adapter for the ubiquitin-editing enzyme A20/TNFAIP3 to bind and inactivate its substrates, Disrupts the interactions between the E3 ubiquitin ligase TRAF3 and TBK1/IKBKE to attenuate 'Lys63'-linked polyubiquitination of TBK1 and thereby IFN-beta production, Recruits also A20/TNFAIP3 to ubiquitinated signaling proteins TRAF6 and RIPK1, leading to their deubiquitination and disruption of IL-1 and TNF-induced NF-kappa-B signaling pathways, Inhibits virus-induced apoptosis by inducing the 'Lys-48'-linked polyubiquitination and degradation of MAVS via recruitment of the E3 ligase ITCH, thereby attenuating MAVS-mediated apoptosis signaling, As a macroautophagy/autophagy receptor, facilitates the xenophagic clearance of pathogenic bacteria such as Salmonella typhimurium and Mycobacterium tuberculosis, Upon NBR1 recruitment to the SQSTM1-ubiquitin condensates, acts as the major recruiter of RB1CC1 to these ubiquitin condensates to promote their autophagic degradation


This is Alpha-1B-glycoprotein protein, from Bovine, contains 503 amino acids, has 5 Ig-like V-type Immunoglobulin domain.

Ig-like V-type

Ig-like V-type

Ig-like V-type

Ig-like V-type

Ig-like V-type


This is IgG receptor FcRn large subunit p51 protein, from Dromedary, contains 355 amino acids, has 1 Ig-like C1-type Immunoglobulin domain.

Ig-like C1-type

Cell surface receptor that transfers passive humoral immunity from the mother to the newborn, Binds to the Fc region of monomeric immunoglobulin gamma and mediates its selective uptake from milk, IgG in the milk is bound at the apical surface of the intestinal epithelium, The resultant FcRn-IgG complexes are transcytosed across the intestinal epithelium and IgG is released from FcRn into blood or tissue fluids, Throughout life, contributes to effective humoral immunity by recycling IgG and extending its half-life in the circulation, Mechanistically, monomeric IgG binding to FcRn in acidic endosomes of endothelial and hematopoietic cells recycles IgG to the cell surface where it is released into the circulation, In addition of IgG, regulates homeostasis of the other most abundant circulating protein albumin/ALB

Belongs to the immunoglobulin superfamily


This is Chaperone protein DnaJ protein, from Bordetella avium (strain 197N), contains 373 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Formamidopyrimidine-DNA glycosylase protein, from Bordetella avium (strain 197N), contains 275 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic protein, from Upland cotton, contains 497 amino acids, has 1 C4-type Zinc finger.


This is Forkhead box protein P1-B protein, from Zebrafish, contains 659 amino acids, has 1 C2H2-type Zinc finger.


This is SAGA-associated factor 11 homolog protein, from Fruit fly, contains 196 amino acids, has 1 SGF11-type Zinc finger.

Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination, Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B, The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription, Required for nuclear receptor-mediated transactivation, Binds independently on SAGA to promoters in an RNA-dependent manner, Binds to mRNA and is essential for total mRNA export from the nucleus, Required to counteract heterochromatin silencing, Controls the development of neuronal connectivity in visual system by being required for accurate axon targeting in the optic lobe, Required for expression of ecdysone-induced genes such as br/broad


This is Zinc finger protein 630 protein, from Human, contains 657 amino acids, has 11 C2H2-type Zinc finger, has 1 C2H2-type 3; degenerate Zinc finger, has 1 C2H2-type 13; degenerate Zinc finger, has 1 C2H2-type 14; degenerate Zinc finger.

C2H2-type 3; degenerate

C2H2-type 13; degenerate

C2H2-type 14; degenerate

May be involved in transcriptional regulation


This is DNA-directed RNA polymerase III subunit RPC10 protein, from Bovine, contains 108 amino acids, has 1 C4-type Zinc finger, has 1 TFIIS-type Zinc finger.

TFIIS-type

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates, Component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs, Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses, Acts as nuclear and cytosolic DNA sensor involved in innate immune response, Can sense non-self dsDNA that serves as template for transcription into dsRNA, The non-self RNA polymerase III transcripts induce type I interferon and NF-kappa-B through the RIG-I pathway (By similarity)

Belongs to the archaeal RpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family


This is Zinc finger protein 181 protein, from Human, contains 571 amino acids, has 11 C2H2-type Zinc finger.


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic protein, from Wild potato, contains 490 amino acids, has 1 C4-type Zinc finger.


This is Formamidopyrimidine-DNA glycosylase protein, from Erythrobacter litoralis (strain HTCC2594), contains 271 amino acids, has 1 FPG-type; degenerate Zinc finger.

FPG-type; degenerate


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Erythrobacter litoralis (strain HTCC2594), contains 282 amino acids, has 1 C4-type Zinc finger.


This is E3 ubiquitin-protein ligase IE2 protein, from HcNPV, contains 375 amino acids, has 1 RING-type Zinc finger.

RING-type

RING-finger E3 ubiquitin ligase that plays an important regulatory role during the initial stages of infection, Migrates to specific nuclear foci early in infection supposely to prepare the sites for viral replication by targeting and ubiquitinating host proteins

Belongs to the alphabaculovirus IE2 protein family


This is Formamidopyrimidine-DNA glycosylase protein, from Sodalis glossinidius (strain morsitans), contains 269 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Sodalis glossinidius (strain morsitans), contains 306 amino acids, has 1 C4-type Zinc finger.


This is Chaperone protein DnaJ protein, from Sodalis glossinidius (strain morsitans), contains 374 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Xanthomonas oryzae pv. oryzae (strain MAFF 311018), contains 295 amino acids, has 1 C4-type Zinc finger.


This is Chaperone protein DnaJ protein, from Xanthomonas oryzae pv. oryzae (strain MAFF 311018), contains 376 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Formamidopyrimidine-DNA glycosylase protein, from Xanthomonas oryzae pv. oryzae (strain MAFF 311018), contains 271 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Zinc finger CCHC domain-containing protein 8 homolog protein, from Fruit fly, contains 553 amino acids, has 1 CCHC-type Zinc finger.

CCHC-type

Scaffolding subunit of the trimeric nuclear exosome targeting (NEXT) complex, a complex that directs a subset of non-coding short-lived RNAs for exosomal degradation, The RNA exosome is fundamental for the degradation of RNA in eukaryotic nuclei, May be involved in pre-mRNA splicing


This is Interleukin-12 subunit beta protein, from Swamp type water buffalo, contains 327 amino acids, has 1 Ig-like C2-type Immunoglobulin domain.

Ig-like C2-type

Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC


This is Mini zinc finger protein 3 protein, from Mouse-ear cress, contains 88 amino acids, has 1 ZF-HD dimerization-type; degenerate Zinc finger.

ZF-HD dimerization-type; degenerate

Inhibits zinc finger homeodomain (ZHD) transcription factors by interacting with them to prevent both their nuclear localization and their DNA-binding properties, Involved in integrating signals from multiple hormones by regulating the expression of specific genes, Promotes the formation of ectopic shoot meristems on leaf margins


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic protein, from Cucumber, contains 523 amino acids, has 1 C4-type Zinc finger.


This is Zinc-finger homeodomain protein 3 protein, from Rice, contains 329 amino acids, has 1 ZF-HD dimerization-type; degenerate Zinc finger.

ZF-HD dimerization-type; degenerate


This is PHD finger protein ALFIN-LIKE 8 protein, from Rice, contains 254 amino acids, has 1 PHD-type Zinc finger.

PHD-type

Histone-binding component that specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes


This is Formamidopyrimidine-DNA glycosylase protein, from Moorella thermoacetica (strain ATCC 39073 / JCM 9320), contains 274 amino acids, has 1 FPG-type Zinc finger.

FPG-type

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents, Acts as DNA glycosylase that recognizes and removes damaged bases, Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG), Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand, Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates


This is Formamidopyrimidine-DNA glycosylase protein, from Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIMB 8255 / S1), contains 281 amino acids, has 1 FPG-type; degenerate Zinc finger.

FPG-type; degenerate


This is Chaperone protein DnaJ protein, from Salinibacter ruber (strain DSM 13855 / M31), contains 388 amino acids, has 1 CR-type Zinc finger.

CR-type

Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion, Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex, GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle, Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding, Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Hahella chejuensis (strain KCTC 2396), contains 310 amino acids, has 1 C4-type Zinc finger.

Component of the acetyl coenzyme A carboxylase (ACC) complex, Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA


This is Chaperone protein DnaJ protein, from Hahella chejuensis (strain KCTC 2396), contains 375 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Formamidopyrimidine-DNA glycosylase protein, from Hahella chejuensis (strain KCTC 2396), contains 271 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Chaperone protein DnaJ protein, from Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CIP 106301 / E264), contains 376 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Formamidopyrimidine-DNA glycosylase protein, from Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CIP 106301 / E264), contains 276 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is PHD finger protein 10 protein, from Bovine, contains 410 amino acids, has 1 PHD-type 1; degenerate Zinc finger, has 1 PHD-type 2; degenerate Zinc finger.

PHD-type 1; degenerate

PHD-type 2; degenerate

Involved in transcription activity regulation by chromatin remodeling, Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and is required for the proliferation of neural progenitors, During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state, The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes, As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF), The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells, The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity)


This is Zinc finger protein 668 protein, from Bovine, contains 619 amino acids, has 16 C2H2-type Zinc finger.

May be involved in transcriptional regulation, May play a role in DNA repair process


This is RING finger protein 148 protein, from Bovine, contains 303 amino acids, has 1 RING-type; atypical Zinc finger.

RING-type; atypical


This is Histone deacetylase complex subunit SAP30L-B protein, from African clawed frog, contains 181 amino acids, has 1 Atypical Zinc finger.

Atypical

Functions as transcription repressor, probably via its interaction with histone deacetylase complexes, Involved in the functional recruitment of the class 1 Sin3-histone deacetylase complex (HDAC) to the nucleolus, Binds DNA, apparently without sequence-specificity, and bends bound double-stranded DNA, Binds phosphoinositol phosphates (phosphoinositol 3-phosphate, phosphoinositol 4-phosphate and phosphoinositol 5-phosphate) via the same basic sequence motif that mediates DNA binding and nuclear import


This is Zinc finger protein 800 protein, from Human, contains 664 amino acids, has 1 C2H2-type 1; degenerate Zinc finger, has 6 C2H2-type Zinc finger.

C2H2-type 1; degenerate


This is Histone H4 transcription factor protein, from Bovine, contains 516 amino acids, has 8 C2H2-type Zinc finger, has 1 C2H2-type 4; degenerate Zinc finger.

C2H2-type 4; degenerate

Transcriptional repressor that binds to the consensus sequence 5'-CGGACGTT-3' and to the RB1 promoter, Transcriptional activator that promotes histone H4 gene transcription at the G1/S phase transition in conjunction with NPAT, Also activates transcription of the ATM and PRKDC genes, Autoregulates its expression by associating with its own promoter (By similarity)


This is General transcription factor IIH subunit 2 protein, from Bovine, contains 395 amino acids, has 1 C4-type Zinc finger.

Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II, In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment, In transcription, TFIIH has an essential role in transcription initiation, When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape, Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription, The N-terminus of GTF2H2 interacts with and regulates XPD whereas an intact C-terminus is required for a successful escape of RNAP II form the promoter


This is Zinc finger protein 667 protein, from Mouse, contains 609 amino acids, has 14 C2H2-type Zinc finger.


This is PAN2-PAN3 deadenylation complex subunit PAN3 protein, from Yellow koji mold, contains 662 amino acids, has 1 C3H1-type Zinc finger.

Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover, PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein pab1, PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex, Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenylation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by xrn1, May also be involved in post-transcriptional maturation of mRNA poly(A) tails, pan3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit pan2 to mRNA via its interaction with RNA and with pab1


This is E3 ubiquitin-protein ligase bre1 protein, from Yellow koji mold, contains 760 amino acids, has 1 RING-type Zinc finger.

RING-type

E3 ubiquitin-protein ligase that mediates monoubiquitination of histone H2B to form H2BK123ub1, H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation


This is Structure-specific endonuclease subunit slx1 protein, from Yellow koji mold, contains 406 amino acids, has 1 SLX1-type Zinc finger.

Catalytic subunit of the slx1-slx4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination, Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA


This is C2H2 type master regulator of conidiophore development brlA protein, from Yellow koji mold, contains 421 amino acids, has 2 C2H2-type Zinc finger.

BrlA, abaA and wetA are pivotal regulators of conidiophore development and conidium maturation (By similarity), They act individually and together to regulate their own expression and that of numerous other sporulation-specific genes (By similarity), Binds promoters of target genes at brlA response elements (BREs) containing the conserved sequence 5'-(C/A)(A/G)AGGG(G/A)-3' (By similarity), Required for conidiophores formation (PubMed:17213655), Controls expression of abaA (PubMed:19850144)


This is Zinc finger protein 284 protein, from Human, contains 593 amino acids, has 1 C2H2-type 1; degenerate Zinc finger, has 1 C2H2-type 2; degenerate Zinc finger, has 11 C2H2-type Zinc finger, has 1 C2H2-type 10; degenerate Zinc finger, has 1 C2H2-type 15; degenerate Zinc finger.

C2H2-type 1; degenerate

C2H2-type 2; degenerate

C2H2-type 10; degenerate

C2H2-type 15; degenerate

May be involved in transcriptional regulation


This is Chaperone protein DnaJ protein, from Magnetospirillum magneticum (strain AMB-1 / ATCC 700264), contains 383 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Protein M2-1 protein, from AMPV, contains 184 amino acids, has 1 C3H1-type Zinc finger.

Essential for viral replication in vivo (By similarity), Plays a role in the association of the matrix protein with the nucleocapsid, which initiates assembly and budding (By similarity)

Belongs to the pneumoviridae M2-1 protein family


This is Formamidopyrimidine-DNA glycosylase protein, from Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849 / C 71), contains 272 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Programmed cell death protein 2 protein, from Bovine, contains 344 amino acids, has 1 MYND-type; atypical Zinc finger.

MYND-type; atypical

May be a DNA-binding protein with a regulatory function, May play an important role in cell death and/or in regulation of cell proliferation (By similarity)


This is Zinc finger protein-like 1 protein, from Bovine, contains 312 amino acids, has 1 B box-type; degenerate Zinc finger, has 1 RING-type; degenerate Zinc finger.

B box-type; degenerate

RING-type; degenerate

Required for cis-Golgi integrity and efficient ER to Golgi transport, Involved in the maintenance of the integrity of the cis-Golgi, possibly via its interaction with GOLGA2/GM130 (By similarity)

Golgi apparatus, cis-Golgi network membrane


This is Polycomb group RING finger protein 1 protein, from Bovine, contains 259 amino acids, has 1 RING-type Zinc finger.

RING-type

Component of the Polycomb group (PcG) multiprotein BCOR complex, a complex required to maintain the transcriptionally repressive state of some genes, such as BCL6 and the cyclin-dependent kinase inhibitor, CDKN1A, Transcriptional repressor that may be targeted to the DNA by BCL6; this transcription repressor activity may be related to PKC signaling pathway, Represses CDKN1A expression by binding to its promoter, and this repression is dependent on the retinoic acid response element (RARE element), Promotes cell cycle progression and enhances cell proliferation as well, May have a positive role in tumor cell growth by down-regulating CDKN1A, Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development, PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility, Within the PRC1-like complex, regulates RNF2 ubiquitin ligase activity, Regulates the expression of DPPA4 and NANOG in the NT2 embryonic carcinoma cells


This is Sodium channel modifier 1 protein, from Zebrafish, contains 249 amino acids, has 1 Matrin-type Zinc finger.

Matrin-type

As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs


This is Cell surface glycoprotein CD200 receptor 1-B protein, from Chicken, contains 243 amino acids, has 1 Ig-like V-type Immunoglobulin domain, has 1 Ig-like C2-type Immunoglobulin domain.

Ig-like V-type

Ig-like C2-type


This is DNA repair protein RadA protein, from Brucella abortus (strain 2308), contains 467 amino acids, has 1 C4-type Zinc finger.

DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks, Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster, Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB, Does not have RecA's homology-searching function

Belongs to the RecA family, RadA subfamily


This is UvrABC system protein A protein, from Brucella abortus (strain 2308), contains 974 amino acids, has 1 C4-type Zinc finger.

The UvrABC repair system catalyzes the recognition and processing of DNA lesions, UvrA is an ATPase and a DNA-binding protein, A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities, When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate

Belongs to the ABC transporter superfamily, UvrA family


This is Formamidopyrimidine-DNA glycosylase protein, from Brucella abortus (strain 2308), contains 293 amino acids, has 1 FPG-type Zinc finger.

FPG-type

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents, Acts as DNA glycosylase that recognizes and removes damaged bases, Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG), Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand, Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates


This is Chaperone protein DnaJ protein, from Brucella abortus (strain 2308), contains 377 amino acids, has 1 CR-type Zinc finger.

CR-type

Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion, Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex, GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle, Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding, Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins


This is Chaperone protein DnaJ protein, from Staphylococcus aureus (strain bovine RF122 / ET3-1), contains 379 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Staphylococcus aureus (strain bovine RF122 / ET3-1), contains 285 amino acids, has 1 C4-type Zinc finger.

Component of the acetyl coenzyme A carboxylase (ACC) complex, Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA


This is Chaperone protein DnaJ protein, from Desulfovibrio alaskensis, contains 375 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Prochlorococcus marinus (strain MIT 9312), contains 293 amino acids, has 1 C4-type Zinc finger.


This is Formamidopyrimidine-DNA glycosylase protein, from Prochlorococcus marinus (strain MIT 9312), contains 293 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Formamidopyrimidine-DNA glycosylase protein, from Thiomicrospira crunogena, contains 280 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Chaperone protein DnaJ protein, from Thiomicrospira crunogena, contains 387 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Thiomicrospira crunogena, contains 284 amino acids, has 1 C4-type Zinc finger.


This is Formamidopyrimidine-DNA glycosylase protein, from Shigella boydii serotype 4 (strain Sb227), contains 269 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Shigella boydii serotype 4 (strain Sb227), contains 304 amino acids, has 1 C4-type Zinc finger.


This is Endonuclease 8 protein, from Shigella boydii serotype 4 (strain Sb227), contains 263 amino acids, has 1 FPG-type Zinc finger.

FPG-type

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents, Acts as DNA glycosylase that recognizes and removes damaged bases, Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine, Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand, Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates


This is Chaperone protein DnaJ protein, from Shigella boydii serotype 4 (strain Sb227), contains 376 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Formamidopyrimidine-DNA glycosylase protein, from Shigella dysenteriae serotype 1 (strain Sd197), contains 269 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Shigella dysenteriae serotype 1 (strain Sd197), contains 304 amino acids, has 1 C4-type Zinc finger.


This is Endonuclease 8 protein, from Shigella dysenteriae serotype 1 (strain Sd197), contains 263 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Chaperone protein DnaJ protein, from Shigella dysenteriae serotype 1 (strain Sd197), contains 376 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Zinc finger protein 821 protein, from Bovine, contains 412 amino acids, has 2 C2H2-type Zinc finger.


This is CXXC-type zinc finger protein 5 protein, from Bovine, contains 317 amino acids, has 1 CXXC-type Zinc finger.

CXXC-type

May indirectly participate in activation of the NF-kappa-B and MAPK pathways, Acts as a mediator of BMP4-mediated modulation of canonical Wnt signaling activity in neural stem cells, Required for DNA damage-induced ATM phosphorylation, p53 activation and cell cycle arrest, Involved in myelopoiesis (By similarity), Binds to the oxygen responsive element of COX4I2 and represses its transcription under hypoxia conditions (4% oxygen), as well as normoxia conditions (20% oxygen), May repress COX4I2 transactivation induced by CHCHD2 and RBPJ (By similarity), Binds preferentially to DNA containing cytidine-phosphate-guanosine (CpG) dinucleotides over CpH (H=A, T, and C), hemimethylated-CpG and hemimethylated-hydroxymethyl-CpG (By similarity)


This is Zinc finger protein 330 protein, from Bovine, contains 320 amino acids, has 4 C4-type Zinc finger.


This is Integrator complex subunit 12 protein, from Bovine, contains 462 amino acids, has 1 PHD-type Zinc finger.

PHD-type

Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing, The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes, Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex

Belongs to the Integrator subunit 12 family