This is Zinc finger and BTB domain-containing protein 22 protein, from Dog, contains 640 amino acids, has 1 C2H2-type 1; atypical Zinc finger, has 2 C2H2-type Zinc finger.

C2H2-type 1; atypical


This is Tapasin protein, from Dog, contains 449 amino acids, has 1 Ig-like C1-type Immunoglobulin domain.

Ig-like C1-type

Involved in the association of MHC class I with transporter associated with antigen processing (TAP) and in the assembly of MHC class I with peptide (peptide loading)


This is DNA-directed RNA polymerase I subunit RPA12 protein, from Rhesus macaque, contains 126 amino acids, has 1 C4-type Zinc finger, has 1 TFIIS-type Zinc finger.

TFIIS-type

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates, Component of RNA polymerase I which synthesizes ribosomal RNA precursors

Belongs to the archaeal RpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family


This is Structure-specific endonuclease subunit SLX1 homolog protein, from African malaria mosquito, contains 273 amino acids, has 1 SLX1-type Zinc finger.

Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination, Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA


This is AN1-type zinc finger protein 2A protein, from Rat, contains 171 amino acids, has 2 AN1-type Zinc finger.


This is Zinc finger-containing ubiquitin peptidase 1 protein, from Rat, contains 577 amino acids, has 3 C2H2-type Zinc finger, has 1 C2H2-type 2; atypical Zinc finger.

C2H2-type 2; atypical

Deubiquitinase with endodeubiquitinase activity that specifically interacts with and cleaves 'Lys-63'-linked long polyubiquitin chains, Shows only weak activity against 'Lys-11' and 'Lys-48'-linked chains, Plays an important role in genome stability pathways, functioning to prevent spontaneous DNA damage and also promote cellular survival in response to exogenous DNA damage, Modulates the ubiquitination status of replication protein A (RPA) complex proteins in response to replication stress

Belongs to the peptidase C78 family, ZUFSP subfamily


This is Zinc finger protein 367 protein, from Rat, contains 340 amino acids, has 2 C2H2-type Zinc finger.

Transcriptional activator, May be involved in transcriptional activation of erythroid genes (By similarity)

Belongs to the krueppel C2H2-type zinc-finger protein family


This is Pre-mRNA-splicing factor SLU7 protein, from Zebrafish, contains 571 amino acids, has 1 CCHC-type Zinc finger.

CCHC-type

Required for pre-mRNA splicing as component of the spliceosome, Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron, Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region, May be involved in the activation of proximal AG, Probably also involved in alternative splicing regulation


This is Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 protein, from Mouse, contains 904 amino acids, has 1 C4-type Zinc finger.


This is PHD finger protein 23A protein, from Western clawed frog, contains 278 amino acids, has 1 PHD-type Zinc finger.

PHD-type

Acts as a negative regulator of autophagy


This is Protein FAR1-RELATED SEQUENCE 1 protein, from Mouse-ear cress, contains 687 amino acids, has 1 SWIM-type Zinc finger.

SWIM-type

Putative transcription activator involved in regulating light control of development


This is Putative mRNA-decapping protein protein, from APMV, contains 360 amino acids, has 1 CCHC-type Zinc finger.

CCHC-type

Might function as a decapping enzyme required for the removal of the 5'-end m7GpppN cap tethered to viral and host mRNAs to allow their decay in cells, In addition to the mRNA cap, probably also efficiently hydrolyzes diphosphoinositol polyphosphates (By similarity)

Belongs to the Nudix hydrolase family, DIPP subfamily


This is Chaperone protein DnaJ protein, from Halobacterium marismortui, contains 384 amino acids, has 1 CR-type Zinc finger.

CR-type

Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion, Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex, GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle, Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding, Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins


This is Zinc finger protein 468 protein, from Human, contains 522 amino acids, has 1 C2H2-type 1; degenerate Zinc finger, has 10 C2H2-type Zinc finger.

C2H2-type 1; degenerate

May be involved in transcriptional regulation


This is Zinc-finger homeodomain protein 5 protein, from Rice, contains 232 amino acids, has 1 ZF-HD dimerization-type; degenerate Zinc finger.

ZF-HD dimerization-type; degenerate


This is Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 9 protein, from Human, contains 703 amino acids, has 1 C4-type Zinc finger.

Belongs to the centaurin gamma-like family


This is Putative Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 7 protein, from Human, contains 663 amino acids, has 1 C4-type Zinc finger.


This is Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 6 protein, from Human, contains 663 amino acids, has 1 C4-type Zinc finger.


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Bacillus clausii, contains 280 amino acids, has 1 C4-type Zinc finger.

Component of the acetyl coenzyme A carboxylase (ACC) complex, Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA


This is Formamidopyrimidine-DNA glycosylase protein, from Bacillus clausii, contains 276 amino acids, has 1 FPG-type Zinc finger.

FPG-type

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents, Acts as DNA glycosylase that recognizes and removes damaged bases, Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG), Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand, Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates


This is Chaperone protein DnaJ protein, from Bacillus clausii, contains 372 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Chaperone protein DnaJ protein, from Legionella pneumophila (strain Lens), contains 379 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Formamidopyrimidine-DNA glycosylase protein, from Legionella pneumophila (strain Lens), contains 274 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Chaperone protein DnaJ protein, from Legionella pneumophila (strain Paris), contains 379 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Formamidopyrimidine-DNA glycosylase protein, from Legionella pneumophila (strain Paris), contains 274 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is UvrABC system protein A protein, from Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394), contains 942 amino acids, has 2 C4-type Zinc finger.

The UvrABC repair system catalyzes the recognition and processing of DNA lesions, UvrA is an ATPase and a DNA-binding protein, A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities, When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate

Belongs to the ABC transporter superfamily, UvrA family


This is Chaperone protein DnaJ protein, from Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394), contains 378 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394), contains 288 amino acids, has 1 C4-type Zinc finger.


This is Formamidopyrimidine-DNA glycosylase protein, from Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394), contains 275 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is DNA repair protein RadA protein, from Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394), contains 453 amino acids, has 1 C4-type Zinc finger.

DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks, Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster, Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB, Does not have RecA's homology-searching function

Belongs to the RecA family, RadA subfamily


This is Nucleoporin NUP42 protein, from African clawed frog, contains 491 amino acids, has 1 C3H1-type Zinc finger.

Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm


This is F-box only protein 30 protein, from Rat, contains 742 amino acids, has 1 TRAF-type Zinc finger.

TRAF-type

Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex, Required for muscle atrophy following denervation


This is Polycomb group RING finger protein 6 protein, from Rat, contains 351 amino acids, has 1 RING-type Zinc finger.

RING-type

Transcriptional repressor, May modulate the levels of histone H3K4Me3 by activating KDM5D histone demethylase, Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development, PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility, Within the PRC1-like complex, regulates RNF2 ubiquitin ligase activity


This is Transcriptional activator VP30 protein, from SEBOV, contains 288 amino acids, has 1 C3H1-type; atypical Zinc finger.

C3H1-type; atypical

Multifunctional protein that acts as a viral transcriptional activator, Promotes read-through of an RNA hairpin in the NP open reading frame to enhance viral transcription, Mechanistically, nonphosphorylated VP30 hexamers form a ternary complex with the viral leader RNA, Clamps the RNA template and the complex VP35-polymerase L together, thereby increasing the polymerase affinity for the RNA template to increase transcription initiation despite the presence of RNA secondary structures, Assists also stop-start transcription at gene junctions to promote transcription of downstream genes, Interaction with NP plays a critical role in transcription initiation by recognizing the RNA stem loop (By similarity), Interaction with host RBBP6 interferes with NP-VP30 interaction and inhibits viral RNA synthesis, Also acts as a suppressor of RNA silencing by interacting with host DICER1 and TARBP2/TRBP (By similarity)

Belongs to the filoviridae transcriptional activator VP30 family


This is T-cell surface glycoprotein CD1b protein, from Ma's night monkey, contains 333 amino acids, has 1 Ig-like Immunoglobulin domain.

Ig-like

Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells


This is Chaperone protein DnaJ 2 protein, from Nocardia farcinica (strain IFM 10152), contains 385 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Formamidopyrimidine-DNA glycosylase protein, from Nocardia farcinica (strain IFM 10152), contains 294 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Chaperone protein DnaJ 1 protein, from Nocardia farcinica (strain IFM 10152), contains 384 amino acids, has 1 CR-type Zinc finger.

CR-type


This is GATA transcription factor 20 protein, from Rice, contains 340 amino acids, has 1 GATA-type Zinc finger.

GATA-type

Transcriptional activator that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters

Belongs to the type IV zinc-finger family, Class C subfamily


This is E3 ubiquitin-protein ligase Os06g0535400 protein, from Rice, contains 251 amino acids, has 1 RING-type; atypical Zinc finger.

RING-type; atypical

Possesses E3 ubiquitin-protein ligase in vitro


This is DEAD-box ATP-dependent RNA helicase 35B protein, from Rice, contains 619 amino acids, has 1 CCHC-type Zinc finger.

CCHC-type

Belongs to the DEAD box helicase family, DDX41 subfamily


This is Squamosa promoter-binding-like protein 12 protein, from Rice, contains 475 amino acids, has 1 SBP-type Zinc finger.

SBP-type

Trans-acting factor that binds specifically to the consensus nucleotide sequence 5'-TNCGTACAA-3' (By similarity), May be involved in panicle development


This is ERAD-associated E3 ubiquitin-protein ligase HRD1 protein, from Rice, contains 500 amino acids, has 1 RING-type; atypical Zinc finger.

RING-type; atypical

Probable component of the HRD1 ubiquitin ligase complex that mediates the rapid degradation of misfolded endoplasmic reticulum (ER) proteins, a process called ER-associated degradation (ERAD)


This is E3 ubiquitin-protein ligase makorin protein, from Rice, contains 368 amino acids, has 4 C3H1-type Zinc finger, has 1 RING-type Zinc finger.

RING-type

E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins


This is Nucleoporin NUP42 protein, from Chicken, contains 413 amino acids, has 1 C3H1-type Zinc finger.


This is Pre-mRNA-splicing factor SLU7 protein, from Chicken, contains 564 amino acids, has 1 CCHC-type Zinc finger.

CCHC-type

Required for pre-mRNA splicing as component of the spliceosome, Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron, Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region, May be involved in the activation of proximal AG, Probably also involved in alternative splicing regulation


This is E3 ubiquitin-protein ligase MIB2 protein, from Chicken, contains 954 amino acids, has 1 ZZ-type Zinc finger, has 2 RING-type Zinc finger.

ZZ-type

RING-type

RING-type

E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins, Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors


This is Methionine aminopeptidase 1 protein, from Chicken, contains 385 amino acids, has 1 C6H2-type Zinc finger.

Cotranslationally removes the N-terminal methionine from nascent proteins, The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val)

Belongs to the peptidase M24A family, Methionine aminopeptidase type 1 subfamily


This is 5'-3' exoribonuclease 2 protein, from Chicken, contains 949 amino acids, has 1 CCHC-type Zinc finger.

CCHC-type

Possesses 5'->3' exoribonuclease activity, May promote the termination of transcription by RNA polymerase II (By similarity)

Belongs to the 5'-3' exonuclease family, XRN2/RAT1 subfamily


This is Histone-lysine N-trimethyltransferase SMYD5 protein, from Chicken, contains 420 amino acids, has 1 MYND-type Zinc finger.

MYND-type

Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4 to form trimethylated histone H4 lysine 20 (H4K20me3) which represents a specific tag for epigenetic transcriptional repression

Belongs to the class V-like SAM-binding methyltransferase superfamily


This is DBIRD complex subunit ZNF326 protein, from Chicken, contains 566 amino acids, has 2 C2H2 AKAP95-type Zinc finger.

C2H2 AKAP95-type

C2H2 AKAP95-type

Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing


This is E3 ubiquitin-protein ligase MARCHF5 protein, from Chicken, contains 281 amino acids, has 1 RING-CH-type Zinc finger.

RING-CH-type

Mitochondrial E3 ubiquitin-protein ligase that plays a crucial role in the control of mitochondrial morphology by acting as a positive regulator of mitochondrial fission, May play a role in the prevention of cell senescence acting as a regulator of mitochondrial quality control


This is Transcriptional adapter 2-alpha protein, from Chicken, contains 446 amino acids, has 1 ZZ-type Zinc finger.

ZZ-type

Component of some complex with histone acetyltransferase activity, Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity), Binds double-stranded DNA, Binds dinucleosomes, probably at the linker region between neighboring nucleosomes, Plays a role in chromatin remodeling (By similarity)


This is TATA box-binding protein-associated factor RNA polymerase I subunit B protein, from Chicken, contains 582 amino acids, has 1 RRN7-type Zinc finger.

Component of RNA polymerase I core factor complex that acts as a GTF2B/TFIIB-like factor and plays a key role in multiple steps during transcription initiation such as pre-initiation complex (PIC) assembly and postpolymerase recruitment events in polymerase I (Pol I) transcription, Binds rDNA promoters and plays a role in Pol I recruitment (By similarity)


This is Inhibitor of growth protein 3 protein, from Chicken, contains 417 amino acids, has 1 PHD-type Zinc finger.

PHD-type

Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A, This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription (By similarity), NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage (By similarity)


This is Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 protein, from Chicken, contains 781 amino acids, has 1 C4-type Zinc finger.

GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6)


This is Inhibitor of growth protein 4 protein, from Chicken, contains 249 amino acids, has 1 PHD-type Zinc finger.

PHD-type

Component of HBO1 complexes, which specifically mediate acetylation of histone H3 at 'Lys-14' (H3K14ac), and have reduced activity toward histone H4, Through chromatin acetylation it may function in DNA replication


This is Zinc finger protein Pegasus protein, from Chicken, contains 421 amino acids, has 5 C2H2-type Zinc finger.

Transcriptional repressor that binds the core 5'GNNTGTNG-3' DNA consensus sequence

Belongs to the Ikaros C2H2-type zinc-finger protein family


This is Pleckstrin homology domain-containing family F member 2 protein, from Chicken, contains 249 amino acids, has 1 FYVE-type Zinc finger.

FYVE-type

May play a role in early endosome fusion upstream of RAB5, hence regulating receptor trafficking and fluid-phase transport, Enhances cellular sensitivity to TNF-induced apoptosis


This is Pre-mRNA-splicing factor RBM22 protein, from Chicken, contains 420 amino acids, has 1 C3H1-type Zinc finger.

Required for pre-mRNA splicing as component of the activated spliceosome, Involved in the first step of pre-mRNA splicing, Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle


This is Tripartite motif-containing protein 59 protein, from Chicken, contains 408 amino acids, has 1 RING-type Zinc finger, has 1 B box-type Zinc finger.

RING-type

B box-type

May serve as a multifunctional regulator for innate immune signaling pathways


This is Chaperone protein DnaJ protein, from Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513), contains 379 amino acids, has 1 CR-type Zinc finger.

CR-type

Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion, Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex, GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle, Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding, Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins


This is Formamidopyrimidine-DNA glycosylase protein, from Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513), contains 274 amino acids, has 1 FPG-type Zinc finger.

FPG-type

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents, Acts as DNA glycosylase that recognizes and removes damaged bases, Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG), Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand, Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates


This is Chaperone protein DnaJ protein, from Mycoplasma hyopneumoniae, contains 368 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Formamidopyrimidine-DNA glycosylase protein, from Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath), contains 271 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Zinc finger protein 664 protein, from Guinea pig, contains 261 amino acids, has 9 C2H2-type Zinc finger.

May be involved in transcriptional regulation


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath), contains 324 amino acids, has 1 C4-type Zinc finger.

Component of the acetyl coenzyme A carboxylase (ACC) complex, Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA


This is Zinc finger protein 30 protein, from Mouse, contains 533 amino acids, has 12 C2H2-type Zinc finger, has 1 C2H2-type 5; degenerate Zinc finger.

C2H2-type 5; degenerate


This is Probable E3 ubiquitin-protein ligase makorin-3 protein, from Mouse, contains 544 amino acids, has 3 C3H1-type Zinc finger, has 1 RING-type Zinc finger.

RING-type

E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins


This is Ras GTPase-activating protein 3 protein, from Mouse, contains 834 amino acids, has 1 Btk-type Zinc finger.

Btk-type

Inhibitory regulator of the Ras-cyclic AMP pathway, May bind inositol tetrakisphosphate (IP4)


This is Chaperone protein DnaJ protein, from Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath), contains 377 amino acids, has 1 CR-type Zinc finger.

CR-type


This is PHD finger protein ALFIN-LIKE 5 protein, from Rice, contains 258 amino acids, has 1 PHD-type Zinc finger.

PHD-type

Histone-binding component that specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes


This is Semaphorin-2A protein, from Caenorhabditis briggsae, contains 656 amino acids, has 1 Ig-like Immunoglobulin domain.

Ig-like

Regulates the formation or stabilization of cell-cell contacts at several stages of epithelial morphogenesis, In early embryonic development, required for proper ventral closure of the epidermis, During male tail morphogenesis, regulates precursor cell sorting and allows the formation of distinct sensory rays, Seems to control cell-cell contact formation through 2 parallel pathways, one involving efn-4 and one involving plx-2 and unc-129, Involved in axon guidance, Probably by binding receptor plx-2, regulates fln-1-mediated remodeling of the actin cytoskeleton and thus axon guidance and/or fasciculation of DD/VD neurons


This is 5'-3' exoribonuclease 2 homolog protein, from Caenorhabditis briggsae, contains 976 amino acids, has 1 CCHC-type Zinc finger.

CCHC-type

Possesses 5'->3' exoribonuclease activity, Plays a role in maintenance of steady-state concentration and turnover of microRNAs (miRNA) by degradation of mature miRNA, Degradation role is enhanced when in complex with paxt-1, Partially redundant to xrn-1 in miRNA guide strand degradation, Implicated in differential regulation of mRNAs such as let-7 by controlling the accumulation of mature miRNA, Positively regulates molting of the pharyngeal cuticle


This is Zinc finger protein 235 protein, from Mouse, contains 645 amino acids, has 13 C2H2-type Zinc finger.


This is Zinc finger protein unc-98 protein, from Caenorhabditis briggsae, contains 308 amino acids, has 3 C2H2-type Zinc finger, has 1 C2H2-type 3; degenerate Zinc finger.

C2H2-type 3; degenerate

Probable transcription factor, Required for muscle structure, Its dual subcellular localization suggests that it may function both as a muscle adhesion complex protein and as a transcription factor, or work together with transcription factors, to influence gene expression, Thought to act as a molecular bridge between unc-97 and mhc-a at the M-line of muscles, possibly in a signaling role (By similarity)


This is Interleukin-12 subunit beta protein, from Woodchuck, contains 327 amino acids, has 1 Ig-like C2-type Immunoglobulin domain.

Ig-like C2-type

Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity, IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues, IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of pro-inflammatory cytokines, IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis (By similarity)


This is Leucine-rich repeat neuronal protein 1 protein, from Mouse, contains 716 amino acids, has 1 Ig-like C2-type Immunoglobulin domain.

Ig-like C2-type


This is MOG interacting and ectopic P-granules protein 1 protein, from Caenorhabditis briggsae, contains 880 amino acids, has 6 C2H2-type Zinc finger, has 1 CCHC-type Zinc finger.

CCHC-type

Has a broad role in development, specifically in the genetic pathway SynMuvB that negatively regulates specification of the vulval cell fate, Required for fem-3 3'-UTR-mediated repression in the regulation of the sperm/oocyte switch, Acts by regulating the translation of fem-3 mRNA, by binding to its 3'-UTR (By similarity)


This is Zinc finger protein 92 protein, from Mouse, contains 488 amino acids, has 8 C2H2-type Zinc finger, has 1 C2H2-type 7; degenerate Zinc finger.

C2H2-type 7; degenerate


This is Zinc finger protein 260 protein, from Mouse, contains 407 amino acids, has 12 C2H2-type Zinc finger, has 1 C2H2-type 2; degenerate Zinc finger.

C2H2-type 2; degenerate

Transcription factor that acts as a cardiac regulator and an effector of alpha1-adrenergic signaling, Binds to PE response elements (PERE) present in the promoter of genes such as ANF/NPPA and acts as a direct transcriptional activator of NPPA, Also acts as a cofactor with GATA4, a key cardiac regulator


This is Formamidopyrimidine-DNA glycosylase protein, from Burkholderia mallei (strain ATCC 23344), contains 272 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Chaperone protein DnaJ protein, from Burkholderia mallei (strain ATCC 23344), contains 376 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Carcinoembryonic antigen-related cell adhesion molecule 3 protein, from Rat, contains 709 amino acids, has 5 Ig-like V-type Immunoglobulin domain, has 1 Ig-like C2-type Immunoglobulin domain.

Ig-like V-type

Ig-like V-type

Ig-like V-type

Ig-like V-type

Ig-like V-type

Ig-like C2-type

Belongs to the immunoglobulin superfamily, CEA family


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Bacillus cereus (strain ZK / E33L), contains 289 amino acids, has 1 C4-type Zinc finger.


This is Formamidopyrimidine-DNA glycosylase protein, from Bacillus cereus (strain ZK / E33L), contains 276 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Chaperone protein DnaJ protein, from Bacillus cereus (strain ZK / E33L), contains 371 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Chaperone protein DnaJ protein, from Burkholderia pseudomallei (strain K96243), contains 376 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Formamidopyrimidine-DNA glycosylase protein, from Burkholderia pseudomallei (strain K96243), contains 276 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Zinc finger protein 830 protein, from African clawed frog, contains 356 amino acids, has 1 C2H2-type Zinc finger.

May act as an important regulator of the cell cycle that participates in the maintenance of genome integrity


This is PHD finger protein 10 protein, from African clawed frog, contains 506 amino acids, has 1 PHD-type 1; degenerate Zinc finger, has 1 PHD-type 2; degenerate Zinc finger.

PHD-type 1; degenerate

PHD-type 2; degenerate

Involved in transcription activity regulation by chromatin remodeling in the context of the neural progenitors-specific chromatin remodeling complex (npBAF complex), May play a role in the proliferation of neural progenitors (By similarity)


This is DNA repair protein complementing XP-A cells homolog protein, from Chinese hamster, contains 97 amino acids, has 1  Zinc finger.

Involved in DNA excision repair, Initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region, Required for UV-induced CHEK1 phosphorylation and the recruitment of CEP164 to cyclobutane pyrimidine dimmers (CPD), sites of DNA damage after UV irradiation (By similarity)


This is CXADR-like membrane protein protein, from Western clawed frog, contains 332 amino acids, has 2 Ig-like C2-type Immunoglobulin domain.

Ig-like C2-type

Ig-like C2-type


This is E3 ubiquitin-protein ligase RMND5A protein, from Western clawed frog, contains 391 amino acids, has 1 RING-Gid-type Zinc finger.

RING-Gid-type

E3 ubiquitin-protein ligase component of the CTLH complex


This is Zinc finger protein 18 protein, from Rat, contains 556 amino acids, has 5 C2H2-type Zinc finger.


This is Transcription factor Sp8 protein, from Chicken, contains 480 amino acids, has 3 C2H2-type Zinc finger.

Transcription factor which plays a key role in limb development, Positively regulates FGF8 expression in the apical ectodermal ridge (AER) and contributes to limb outgrowth in embryos

Belongs to the Sp1 C2H2-type zinc-finger protein family


This is Sialic acid-binding Ig-like lectin 13 protein, from Chimpanzee, contains 387 amino acids, has 1 Ig-like V-type Immunoglobulin domain, has 2 Ig-like C2-type Immunoglobulin domain.

Ig-like V-type

Ig-like C2-type

Ig-like C2-type

Putative adhesion molecule that mediates sialic-acid dependent binding to cells

Belongs to the immunoglobulin superfamily, SIGLEC (sialic acid binding Ig-like lectin) family


This is Chaperone protein DnaJ protein, from Bacteroides fragilis (strain YCH46), contains 394 amino acids, has 1 CR-type Zinc finger.

CR-type

Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion, Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex, GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle, Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding, Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins


This is Squamosa promoter-binding-like protein 11 protein, from Rice, contains 343 amino acids, has 1 SBP-type Zinc finger.

SBP-type

Trans-acting factor that binds specifically to the consensus nucleotide sequence 5'-TNCGTACAA-3' (By similarity), May be involved in panicle development


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46), contains 291 amino acids, has 1 C4-type Zinc finger.

Component of the acetyl coenzyme A carboxylase (ACC) complex, Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA


This is Formamidopyrimidine-DNA glycosylase protein, from Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46), contains 275 amino acids, has 1 FPG-type Zinc finger.

FPG-type

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents, Acts as DNA glycosylase that recognizes and removes damaged bases, Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG), Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand, Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates


This is Chaperone protein DnaJ protein, from Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46), contains 375 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Mannheimia succiniciproducens (strain MBEL55E), contains 295 amino acids, has 1 C4-type Zinc finger.


This is Chaperone protein DnaJ protein, from Mannheimia succiniciproducens (strain MBEL55E), contains 376 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Chaperone protein DnaJ protein, from Borrelia bavariensis, contains 364 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Tripartite terminase subunit 1 protein, from EHV-2, contains 728 amino acids, has 1 C3H1-type Zinc finger.

Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging, Forms a tripartite terminase complex together with TRM2 and TRM3 in the host cytoplasm, Once the complex reaches the host nucleus, it interacts with the capsid portal vertex, This portal forms a ring in which genomic DNA is translocated into the capsid, TRM1 carries an endonuclease activity that plays an important role for the cleavage of concatemeric viral DNA into unit length genomes

Belongs to the herpesviridae TRM1 protein family


This is DNA primase protein, from EHV-2, contains 884 amino acids, has 1 CHC2-type Zinc finger.

Essential component of the helicase/primase complex, Unwinds the DNA at the replication forks and generates single-stranded DNA for both leading and lagging strand synthesis, The primase initiates primer synthesis and thereby produces large amount of short RNA primers on the lagging strand that the polymerase elongates using dNTPs

Belongs to the herpesviridae DNA primase family


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Yersinia pseudotuberculosis serotype I (strain IP32953), contains 304 amino acids, has 1 C4-type Zinc finger.


This is Chaperone protein DnaJ protein, from Yersinia pseudotuberculosis serotype I (strain IP32953), contains 379 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Formamidopyrimidine-DNA glycosylase protein, from Yersinia pseudotuberculosis serotype I (strain IP32953), contains 269 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1-B protein, from Zebrafish, contains 622 amino acids, has 1 Ig-like C2-type Immunoglobulin domain.

Ig-like C2-type

May play a role in regulating axonal regeneration and plasticity in the adult central nervous system


This is rRNA N6-adenosine-methyltransferase ZCCHC4 protein, from Western clawed frog, contains 487 amino acids, has 1 GRF-type Zinc finger, has 1 CCHC-type Zinc finger.

GRF-type

CCHC-type

rRNA N6-methyltransferase that specifically methylates the adenine in position 4220 of 28S rRNA, N6-methylation of adenine(4220) in 28S rRNA is required for translation


This is Transcription factor IIIB 50 kDa subunit protein, from African clawed frog, contains 396 amino acids, has 1 TFIIB-type Zinc finger.

TFIIB-type

General activator of RNA polymerase III transcription, Factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites, Contributes to the regulation of gene expression; functions as activator in the absence of oxidative stress, Down-regulates expression of target genes in response to oxidative stress, Overexpression protects cells against apoptosis in response to oxidative stress


This is Nuclear receptor subfamily 2 group C member 1-B protein, from African clawed frog, contains 637 amino acids, has 2 NR C4-type Zinc finger.

NR C4-type

NR C4-type

Orphan nuclear receptor, Binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism, Primarily repressor of a broad range of genes, Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences (By similarity)

Belongs to the nuclear hormone receptor family, NR2 subfamily


This is Inhibitor of growth protein 3 protein, from Western clawed frog, contains 417 amino acids, has 1 PHD-type Zinc finger.

PHD-type

Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A, This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription (By similarity), NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage (By similarity)


This is E3 ubiquitin-protein ligase ZNRF1 protein, from African clawed frog, contains 195 amino acids, has 1 RING-type; atypical Zinc finger.

RING-type; atypical

E3 ubiquitin-protein ligase that plays a role in neuron cells differentiation, Plays a role in the establishment and maintenance of neuronal transmission and plasticity


This is Cell adhesion molecule 4 protein, from African clawed frog, contains 390 amino acids, has 1 Ig-like V-type Immunoglobulin domain, has 2 Ig-like C2-type Immunoglobulin domain.

Ig-like V-type

Ig-like C2-type

Ig-like C2-type


This is Protein FAM170A protein, from Crab-eating macaque, contains 283 amino acids, has 1 C2H2-type; degenerate Zinc finger.

C2H2-type; degenerate

Acts as a nuclear transcription factor that positively regulates the expression of heat shock genes, Binds to heat shock promoter elements (HSE) (By similarity)


This is Transcriptional activator protein protein, from TYLCSV, contains 135 amino acids, has 1  Zinc finger.

Strong activator of the late viral genes promoters, Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs, TrAP suppresses the host RNA silencing by inhibiting adenosine kinase 2 (ADK2), a kinase involved in a general methylation pathway, Also suppresses the host basal defense by interacting with and inhibiting SNF1 kinase, a key regulator of cell metabolism implicated in innate antiviral defense, Determines pathogenicity (By similarity)

Belongs to the geminiviridae transcriptional activator protein family


This is Chaperone protein DnaJ protein, from Symbiobacterium thermophilum (strain T / IAM 14863), contains 386 amino acids, has 1 CR-type Zinc finger.

CR-type


This is PHD finger protein PERSISTENT TAPETAL CELL 1 protein, from Rice, contains 679 amino acids, has 1 PHD-type Zinc finger.

PHD-type

Probable transcriptional activator required for tapetal programmed cell death (PCD) and degeneration, and pollen development in anthers


This is Zinc finger AN1 domain-containing stress-associated protein 12 protein, from Mouse-ear cress, contains 186 amino acids, has 2 AN1-type Zinc finger.

May be involved in environmental stress response


This is RING-H2 finger protein ATL65 protein, from Mouse-ear cress, contains 411 amino acids, has 1 RING-type; atypical Zinc finger.

RING-type; atypical

Belongs to the RING-type zinc finger family, ATL subfamily


This is Zinc finger protein ZAT5 protein, from Mouse-ear cress, contains 286 amino acids, has 2 C2H2-type Zinc finger.

Probable transcription factor that may be involved in stress responses


This is Zinc-finger homeodomain protein 6 protein, from Rice, contains 255 amino acids, has 1 ZF-HD dimerization-type; degenerate Zinc finger.

ZF-HD dimerization-type; degenerate


This is Zinc finger protein 776 protein, from Human, contains 518 amino acids, has 1 C2H2-type 1; degenerate Zinc finger, has 1 C2H2-type 2; degenerate Zinc finger, has 8 C2H2-type Zinc finger, has 1 C2H2-type 10; degenerate Zinc finger.

C2H2-type 1; degenerate

C2H2-type 2; degenerate

C2H2-type 10; degenerate

May be involved in transcriptional regulation

Belongs to the krueppel C2H2-type zinc-finger protein family


This is Zinc finger protein 772 protein, from Human, contains 489 amino acids, has 10 C2H2-type Zinc finger.


This is CD276 antigen homolog protein, from African clawed frog, contains 308 amino acids, has 1 Ig-like V-type Immunoglobulin domain, has 1 Ig-like C2-type Immunoglobulin domain.

Ig-like V-type

Ig-like C2-type

Belongs to the immunoglobulin superfamily, BTN/MOG family


This is SH3 and cysteine-rich domain-containing protein 3 protein, from Western clawed frog, contains 337 amino acids, has 1 Phorbol-ester/DAG-type Zinc finger.

Phorbol-ester/DAG-type

Required for normal excitation-contraction coupling in skeletal muscle and for normal muscle contraction in response to membrane depolarization, Required for normal Ca(2+) release from the sarcplasmic reticulum, which ultimately leads to muscle contraction, Probably functions via its effects on muscle calcium channels, Increases CACNA1S channel activity, in addition to its role in enhancing the expression of CACNA1S at the cell membrane, Has a redundant role in promoting the expression of the calcium channel CACNA1S at the cell membrane


This is E3 ubiquitin-protein ligase MARCHF3 protein, from Western clawed frog, contains 251 amino acids, has 1 RING-CH-type Zinc finger.

RING-CH-type

E3 ubiquitin-protein ligase which may be involved in endosomal trafficking, E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates


This is Integrator complex subunit 12 protein, from Rat, contains 461 amino acids, has 1 PHD-type Zinc finger.

PHD-type

Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing, The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes, Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex

Belongs to the Integrator subunit 12 family


This is Replication initiator 1 protein, from Rat, contains 548 amino acids, has 1 C2H2-type 1; atypical Zinc finger, has 13 C2H2-type Zinc finger, has 1 C2H2-type 4; atypical Zinc finger.

C2H2-type 1; atypical

C2H2-type 4; atypical

Sequence-specific double-stranded DNA-binding protein required for initiation of chromosomal DNA replication, Binds on 5'-ATT-3' reiterated sequences downstream of the origin of bidirectional replication (OBR) and a second, homologous ATT sequence of opposite orientation situated within the OBR zone, Facilitates DNA bending (By similarity)


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic protein, from Korean ginseng, contains 487 amino acids, has 1 C4-type Zinc finger.

Component of the acetyl coenzyme A carboxylase (ACC) complex, Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA


This is DNA primase protein, from Rickettsia typhi (strain ATCC VR-144 / Wilmington), contains 593 amino acids, has 1 CHC2-type Zinc finger.

RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication


This is DNA repair protein RadA protein, from Rickettsia typhi (strain ATCC VR-144 / Wilmington), contains 445 amino acids, has 1 C4-type Zinc finger.

DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks, Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster, Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB, Does not have RecA's homology-searching function

Belongs to the RecA family, RadA subfamily


This is Primosomal protein N' protein, from Rickettsia typhi (strain ATCC VR-144 / Wilmington), contains 648 amino acids, has 2 C4-type Zinc finger.

Involved in the restart of stalled replication forks, Recognizes and binds the arrested nascent DNA chain at stalled replication forks, It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA

Belongs to the helicase family, PriA subfamily


This is Chaperone protein DnaJ protein, from Rickettsia typhi (strain ATCC VR-144 / Wilmington), contains 370 amino acids, has 1 CR-type Zinc finger.

CR-type

Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion, Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex, GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle, Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding, Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins


This is UvrABC system protein A protein, from Rickettsia typhi (strain ATCC VR-144 / Wilmington), contains 953 amino acids, has 1 C4-type Zinc finger.

The UvrABC repair system catalyzes the recognition and processing of DNA lesions, UvrA is an ATPase and a DNA-binding protein, A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities, When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate

Belongs to the ABC transporter superfamily, UvrA family


This is mRNA export factor ICP27 homolog protein, from MuHV-1, contains 841 amino acids, has 1 CHC2-type Zinc finger.

Immediate early (EI) protein that plays many roles during productive infection including regulation of viral gene expression and nuclear export of intronless viral RNAs

Belongs to the HHV-1 ICP27 protein family


This is Serine/arginine-rich splicing factor RSZ21A protein, from Rice, contains 185 amino acids, has 1 CCHC-type Zinc finger.

CCHC-type

Belongs to the splicing factor SR family


This is Probable DNA helicase MCM9 protein, from Rice, contains 674 amino acids, has 1 C4-type Zinc finger.

Probable DNA helicase that may play a role in DNA repair during meiosis


This is Receptor homology region, transmembrane domain- and RING domain-containing protein 2 protein, from Rice, contains 461 amino acids, has 1 RING-type; atypical Zinc finger.

RING-type; atypical

Involved in the trafficking of vacuolar proteins, May function as a sorting receptor for protein trafficking to the protein storage vacuole (PSV) (By similarity)


This is Zinc finger protein 512 protein, from Mouse, contains 562 amino acids, has 3 C2H2-type Zinc finger.


This is Zinc finger protein 629 protein, from Mouse, contains 867 amino acids, has 19 C2H2-type Zinc finger.


This is Chaperone protein DnaJ 2 protein, from Propionibacterium acnes, contains 380 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Chaperone protein DnaJ 1 protein, from Propionibacterium acnes, contains 392 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Chaperone protein DnaJ protein, from Leifsonia xyli subsp. xyli (strain CTCB07), contains 369 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Formamidopyrimidine-DNA glycosylase protein, from Leifsonia xyli subsp. xyli (strain CTCB07), contains 297 amino acids, has 1 FPG-type Zinc finger.

FPG-type

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents, Acts as DNA glycosylase that recognizes and removes damaged bases, Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG), Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand, Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates


This is Chaperone protein DnaJ protein, from Desulfotalea psychrophila (strain LSv54 / DSM 12343), contains 373 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Formamidopyrimidine-DNA glycosylase protein, from Desulfotalea psychrophila (strain LSv54 / DSM 12343), contains 277 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is E3 SUMO-protein ligase SIZ2 protein, from Rice, contains 813 amino acids, has 1 PHD-type Zinc finger, has 1 SP-RING-type Zinc finger.

PHD-type

SP-RING-type

Probable SUMO E3 ligase that may regulate Pi starvation responses


This is Splicing factor U2af small subunit B protein, from Rice, contains 304 amino acids, has 2 C3H1-type Zinc finger.


This is Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 homolog protein, from Rice, contains 726 amino acids, has 1 RTR1-type Zinc finger.

Putative RNA polymerase II subunit B1 C-terminal domain (CTD) phosphatase involved in RNA polymerase II transcription regulation


This is Zinc finger protein 324B protein, from Human, contains 544 amino acids, has 9 C2H2-type Zinc finger.

May be involved in transcriptional regulation


This is Four and a half LIM domains protein 5 protein, from Rat, contains 284 amino acids, has 1 C4-type Zinc finger.

May be involved in the regulation of spermatogenesis, Stimulates CREM transcriptional activity in a phosphorylation-independent manner (By similarity)


This is E3 ubiquitin-protein ligase RNF181 protein, from Rat, contains 165 amino acids, has 1 RING-type; atypical Zinc finger.

RING-type; atypical

E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, Catalyzes monoubiquitination of 26S proteasome subunit PSMC2/RPT1


This is PHD finger protein 23 protein, from Rat, contains 334 amino acids, has 1 PHD-type Zinc finger.

PHD-type

Acts as a negative regulator of autophagy, through promoting ubiquitination and degradation of LRSAM1, an E3 ubiquitin ligase that promotes autophagy in response to starvation or infecting bacteria


This is Microfibril-associated glycoprotein 3 protein, from Rat, contains 347 amino acids, has 1 Ig-like C2-type Immunoglobulin domain.

Ig-like C2-type

Component of the elastin-associated microfibrils


This is Microfibrillar-associated protein 3-like protein, from Rat, contains 409 amino acids, has 1 Ig-like C2-type Immunoglobulin domain.

Ig-like C2-type

May participate in the nuclear signaling of EGFR and MAPK1/ERK2


This is Myelin protein zero-like protein 1 protein, from Rat, contains 270 amino acids, has 1 Ig-like V-type Immunoglobulin domain.

Ig-like V-type

Cell surface receptor, which is involved in signal transduction processes, Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2, Is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases, May be involved in regulation of integrin-mediated cell motility (By similarity)


This is Zinc finger Y-chromosomal protein protein, from Chimpanzee, contains 801 amino acids, has 12 C2H2-type Zinc finger, has 1 C2H2-type 2; atypical Zinc finger.

C2H2-type 2; atypical

Probable transcriptional activator, Binds to the consensus sequence 5'-AGGCCY-3' (By similarity)

Belongs to the krueppel C2H2-type zinc-finger protein family, ZFX/ZFY subfamily


This is Transcription factor Sp5 protein, from Human, contains 398 amino acids, has 3 C2H2-type Zinc finger.

Binds to GC boxes promoters elements, Probable transcriptional activator that has a role in the coordination of changes in transcription required to generate pattern in the developing embryo (By similarity)


This is RNA interference defective protein 11 protein, from Caenorhabditis elegans, contains 316 amino acids, has 1 RING-type; degenerate Zinc finger.

RING-type; degenerate

In complex with rde-10, required in the endogenous and exogenous siRNA pathway for biogenesis and accumulation of secondary small interfering RNA (siRNA) intermediates, such as 22G-siRNAs derived from ergo-1 targets


This is Postreplication repair E3 ubiquitin-protein ligase RAD18 protein, from Yeast, contains 491 amino acids, has 1 RING-type Zinc finger, has 1 UBZ4-type Zinc finger.

RING-type

E3 RING-finger protein, member of the UBC2/RAD6 epistasis group, Associates to the E2 ubiquitin conjugating enzyme UBC2/RAD6 to form the UBC2-RAD18 ubiquitin ligase complex involved in postreplicative repair (PRR) of damaged DNA


This is Pre-mRNA-splicing factor CWC2 protein, from Yeast, contains 339 amino acids, has 1 C3H1-type Zinc finger.

Involved in the first step of pre-mRNA splicing, Required for cell growth and cell cycle control, Plays a role in the levels of the U1, U4, U5 and U6 snRNAs and the maintenance of the U4/U6 snRNA complex, May provide the link between the 'nineteen complex' NTC spliceosome protein complex and the spliceosome through the U6 snRNA, Associates predominantly with U6 snRNAs in assembled active spliceosomes, Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle (By similarity)


This is Chromatin modification-related protein YNG2 protein, from Yeast, contains 285 amino acids, has 1 PHD-type Zinc finger.

PHD-type

Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A, The NuA4 complex is also involved in DNA repair, Involved in cell cycle progression and meiosis (By similarity)


This is tRNA:m(4)X modification enzyme TRM13 protein, from Yeast, contains 457 amino acids, has 1 CHHC U11-48K-type Zinc finger.

CHHC U11-48K-type

tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His)

Belongs to the methyltransferase TRM13 family


This is PAN2-PAN3 deadenylation complex subunit PAN3 protein, from Yeast, contains 660 amino acids, has 1 C3H1-type Zinc finger.

Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover, PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1, PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex, Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenylation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1, May also be involved in post-transcriptional maturation of mRNA poly(A) tails, PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and with PAB1

Belongs to the protein kinase superfamily, PAN3 family


This is Vacuolar protein sorting-associated protein 27 protein, from Yeast, contains 732 amino acids, has 1 FYVE-type; atypical Zinc finger.

FYVE-type; atypical

Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane


This is Structure-specific endonuclease subunit SLX1 protein, from Yeast, contains 346 amino acids, has 1 SLX1-type Zinc finger.

Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination, Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA


This is E3 ubiquitin-protein ligase BRE1 protein, from Yeast, contains 691 amino acids, has 1 RING-type Zinc finger.

RING-type

E3 ubiquitin-protein ligase that mediates monoubiquitination of histone H2B to form H2BK123ub1, H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation


This is JmjC domain-containing histone demethylation protein 1 protein, from Yeast, contains 514 amino acids, has 1 PHD-type Zinc finger.

PHD-type

Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code

Belongs to the JHDM1 histone demethylase family


This is Protein FYV10 protein, from Yeast, contains 511 amino acids, has 1 RING-Gid-type Zinc finger.

RING-Gid-type

Involved in the proteasome-dependent degradation of fructose-1,6-bisphosphatase


This is Pre-mRNA-splicing factor CWC2 protein, from Yeast, contains 382 amino acids, has 1 C3H1-type Zinc finger.


This is Transcription factor BYE1 protein, from Yeast, contains 822 amino acids, has 1 PHD-type Zinc finger.

PHD-type

Negative regulator of transcription elongation


This is Branchpoint-bridging protein protein, from Yeast, contains 605 amino acids, has 1 CCHC-type Zinc finger.

CCHC-type

Necessary for the splicing of pre-mRNA, Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns (By similarity)


This is JmjC domain-containing histone demethylation protein 1 protein, from Yeast, contains 510 amino acids, has 1 PHD-type Zinc finger.

PHD-type


This is tRNA:m(4)X modification enzyme TRM13 protein, from Yeast, contains 464 amino acids, has 1 CHHC U11-48K-type Zinc finger.

CHHC U11-48K-type


This is Chromatin modification-related protein YNG2 protein, from Yeast, contains 283 amino acids, has 1 PHD-type Zinc finger.

PHD-type


This is RNA polymerase II transcription factor B subunit 3 protein, from Yeast, contains 346 amino acids, has 1 RING-type Zinc finger.

RING-type

Acts as component of the general transcription and DNA repair factor IIH (TFIIH or factor B), which is essential for both basal and activated transcription, and is involved in nucleotide excision repair (NER) of damaged DNA, TFIIH as CTD kinase activity and DNA-dependent ATPase activity, and is essential for polymerase II transcription (By similarity)


This is General transcription and DNA repair factor IIH subunit TFB4 protein, from Yeast, contains 340 amino acids, has 1 C4-type Zinc finger.

Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II, In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment, In transcription, TFIIH has an essential role in transcription initiation, When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape, Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription


This is E3 ubiquitin-protein ligase BRE1 protein, from Yeast, contains 700 amino acids, has 1 RING-type Zinc finger.

RING-type


This is Postreplication repair E3 ubiquitin-protein ligase RAD18 protein, from Yeast, contains 344 amino acids, has 1 RING-type Zinc finger, has 1 UBZ4-type Zinc finger.

RING-type


This is JmjC domain-containing histone demethylation protein 1 protein, from Yeast, contains 478 amino acids, has 1 PHD-type Zinc finger.

PHD-type


This is Structure-specific endonuclease subunit SLX1 protein, from Yeast, contains 288 amino acids, has 1 SLX1-type Zinc finger.


This is Vacuolar protein sorting-associated protein 27 protein, from Yeast, contains 603 amino acids, has 1 FYVE-type; atypical Zinc finger.

FYVE-type; atypical


This is PAN2-PAN3 deadenylation complex subunit PAN3 protein, from Yeast, contains 656 amino acids, has 1 C3H1-type Zinc finger.


This is tRNA:m(4)X modification enzyme TRM13 protein, from Yeast, contains 434 amino acids, has 1 CHHC U11-48K-type Zinc finger.

CHHC U11-48K-type


This is Pre-mRNA-splicing factor CWC2 protein, from Yeast, contains 337 amino acids, has 1 C3H1-type Zinc finger.


This is Postreplication repair E3 ubiquitin-protein ligase RAD18 protein, from Yeast, contains 427 amino acids, has 1 RING-type Zinc finger, has 1 UBZ4-type Zinc finger.

RING-type


This is E3 ubiquitin-protein ligase BRE1 protein, from Yeast, contains 663 amino acids, has 1 RING-type Zinc finger.

RING-type


This is Chromatin modification-related protein YNG2 protein, from Yeast, contains 295 amino acids, has 1 PHD-type Zinc finger.

PHD-type


This is Chaperone protein DnaJ protein, from Erwinia carotovora subsp. atroseptica, contains 379 amino acids, has 1 CR-type Zinc finger.

CR-type

Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion, Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex, GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle, Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding, Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Erwinia carotovora subsp. atroseptica, contains 305 amino acids, has 1 C4-type Zinc finger.

Component of the acetyl coenzyme A carboxylase (ACC) complex, Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA


This is Endonuclease 8 protein, from Erwinia carotovora subsp. atroseptica, contains 263 amino acids, has 1 FPG-type Zinc finger.

FPG-type

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents, Acts as DNA glycosylase that recognizes and removes damaged bases, Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine, Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand, Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates


This is Formamidopyrimidine-DNA glycosylase protein, from Erwinia carotovora subsp. atroseptica, contains 269 amino acids, has 1 FPG-type Zinc finger.

FPG-type

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents, Acts as DNA glycosylase that recognizes and removes damaged bases, Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG), Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand, Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates


This is Polycomb protein suz12-A protein, from Zebrafish, contains 657 amino acids, has 1 C2H2-type Zinc finger.

Polycomb group (PcG) protein, Component of the prc2/eed-ezh2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene (By similarity)

Belongs to the VEFS (VRN2-EMF2-FIS2-SU(Z)12) family


This is rRNA N6-adenosine-methyltransferase ZCCHC4 protein, from African clawed frog, contains 489 amino acids, has 1 GRF-type Zinc finger, has 1 CCHC-type Zinc finger.

GRF-type

CCHC-type

rRNA N6-methyltransferase that specifically methylates the adenine in position 4220 of 28S rRNA, N6-methylation of adenine(4220) in 28S rRNA is required for translation


This is RAS guanyl-releasing protein 2-B protein, from African clawed frog, contains 594 amino acids, has 1 Phorbol-ester/DAG-type Zinc finger.

Phorbol-ester/DAG-type

Functions as a calcium- and DAG-regulated nucleotide exchange factor specifically activating Rap through the exchange of bound GDP for GTP, May function in cell aggregation and adhesion


This is Zinc finger CCCH domain-containing protein 15 protein, from African clawed frog, contains 426 amino acids, has 2 C3H1-type Zinc finger.

Protects drg1 from proteolytic degradation


This is E3 ubiquitin ligase Rnf121 protein, from African clawed frog, contains 327 amino acids, has 1 RING-type; atypical Zinc finger.

RING-type; atypical

E3 ubiquitin ligase which accepts ubiquitin and transfers it to substrates thereby promoting their degradation by the endoplasmic reticulum-associated degradation (ERAD) pathway which is a pathway involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins (By similarity), May regulate the unfolded protein response to reduce endoplasmic reticulum stress (By similarity)


This is Zinc finger protein 787 protein, from Human, contains 382 amino acids, has 7 C2H2-type Zinc finger.

May be involved in transcriptional regulation


This is RNA-binding protein 5-B protein, from African clawed frog, contains 749 amino acids, has 1 RanBP2-type Zinc finger.

Component of the spliceosome A complex, Regulates alternative splicing of a number of mRNAs, May modulate splice site pairing after recruitment of the U1 and U2 snRNPs to the 5' and 3' splice sites of the intron (By similarity)


This is Calcium-binding and coiled-coil domain-containing protein 2 protein, from Western clawed frog, contains 470 amino acids, has 1 UBZ1-type Zinc finger.

Xenophagy-specific receptor required for autophagy-mediated intracellular bacteria degradation (By similarity), Acts as an effector protein of galectin-sensed membrane damage that restricts the proliferation of infecting pathogens upon entry into the cytosol by targeting galectin-associated bacteria for autophagy (By similarity), Initially orchestrates bacteria targeting to autophagosomes and subsequently ensures pathogen degradation by regulating pathogen-containing autophagosome maturation (By similarity), May play a role in ruffle formation and actin cytoskeleton organization and seems to negatively regulate constitutive secretion (By similarity)


This is Peroxisome assembly protein 12-B protein, from African clawed frog, contains 353 amino acids, has 1 RING-type; degenerate Zinc finger.

RING-type; degenerate

Component of a retrotranslocation channel required for peroxisome organization by mediating export of the PEX5 receptor from peroxisomes to the cytosol, thereby promoting PEX5 recycling (PubMed:35931083), The retrotranslocation channel is composed of PEX2, PEX10 and PEX12; each subunit contributing transmembrane segments that coassemble into an open channel that specifically allows the passage of PEX5 through the peroxisomal membrane (By similarity), PEX12 also regulates PEX5 recycling by activating the E3 ubiquitin-protein ligase activity of PEX10 (By similarity), When PEX5 recycling is compromised, PEX12 stimulates PEX10-mediated polyubiquitination of PEX5, leading to its subsequent degradation (By similarity)


This is TANK-binding kinase 1-binding protein 1 protein, from Rat, contains 613 amino acids, has 1 UBZ1-type Zinc finger.

Adapter protein which constitutively binds TBK1 and IKBKE playing a role in antiviral innate immunity, Essential for the efficient induction of IRF-dependent transcription following infection with Sendai virus (By similarity)


This is Non-structural maintenance of chromosomes element 1 homolog protein, from Zebrafish, contains 239 amino acids, has 1 RING-type; atypical Zinc finger.

RING-type; atypical

RING-type zinc finger-containing E3 ubiquitin ligase that assembles with melanoma antigen protein (MAGE) to catalyze the direct transfer of ubiquitin from E2 ubiquitin-conjugating enzyme to a specific substrate, Within MAGE-RING ubiquitin ligase complex, MAGE stimulates and specifies ubiquitin ligase activity likely through recruitment and/or stabilization of the E2 ubiquitin-conjugating enzyme at the E3:substrate complex, Involved in maintenance of genome integrity, DNA damage response and DNA repair


This is MBT domain-containing protein 1 protein, from Western clawed frog, contains 651 amino acids, has 1 FCS-type Zinc finger.

FCS-type

Chromatin reader component of the NuA4 histone acetyltransferase complex, a multiprotein complex involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A, The NuA4 complex plays a direct role in repair of DNA double-strand breaks (DSBs) by promoting homologous recombination (HR), MBTD1 specifically recognizes and binds monomethylated and dimethylated 'Lys-20' on histone H4 (H4K20me1 and H4K20me2, respectively), In the NuA4 complex, MBTD1 promotes recruitment of the complex to H4K20me marks by competing with TP53BP1 for binding to H4K20me, Following recruitment to H4K20me at DNA breaks, the NuA4 complex catalyzes acetylation of 'Lys-15' on histone H2A (H2AK15), blocking the ubiquitination mark required for TP53BP1 localization at DNA breaks, thereby promoting homologous recombination (HR)


This is E3 ubiquitin-protein ligase RNF126 protein, from Western clawed frog, contains 311 amino acids, has 1 C4-type Zinc finger, has 1 RING-type Zinc finger.

RING-type

E3 ubiquitin-protein ligase that mediates ubiquitination oF target proteins, Depending on the associated E2 ligase, mediates 'Lys-48'- and 'Lys-63'-linked polyubiquitination of substrates, Part of a BAG6-dependent quality control process ensuring that proteins of the secretory pathway that are mislocalized to the cytosol are degraded by the proteasome, Probably acts by providing the ubiquitin ligase activity associated with the BAG6 complex and be responsible for ubiquitination of the hydrophobic mislocalized proteins and their targeting to the proteasome


This is Zinc finger protein 830 protein, from Western clawed frog, contains 357 amino acids, has 1 C2H2-type Zinc finger.

May act as an important regulator of the cell cycle that participates in the maintenance of genome integrity


This is Zinc finger protein ZIC 3 protein, from Western clawed frog, contains 441 amino acids, has 1 C2H2-type 1; atypical Zinc finger, has 1 C2H2-type 2; atypical Zinc finger, has 3 C2H2-type Zinc finger.

C2H2-type 1; atypical

C2H2-type 2; atypical

Probably acts as a transcriptional activator, May bind to the minimal GLI-consensus sequence 5'-GGGTGGTC-3', Can determine the ectodermal cell fate and promote the earliest step of neural and neural crest development, Involved in establishing left-right asymmetry in the embryo (By similarity)

Belongs to the GLI C2H2-type zinc-finger protein family


This is Tripartite terminase subunit 1 protein, from EHV-1, contains 766 amino acids, has 1 C3H1-type Zinc finger.

Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging, Forms a tripartite terminase complex together with TRM2 and TRM3 in the host cytoplasm, Once the complex reaches the host nucleus, it interacts with the capsid portal vertex, This portal forms a ring in which genomic DNA is translocated into the capsid, TRM1 carries an endonuclease activity that plays an important role for the cleavage of concatemeric viral DNA into unit length genomes

Belongs to the herpesviridae TRM1 protein family


This is Polycomb group RING finger protein 1 protein, from Rat, contains 243 amino acids, has 1 RING-type Zinc finger.

RING-type

Component of the Polycomb group (PcG) multiprotein BCOR complex, a complex required to maintain the transcriptionally repressive state of some genes, such as BCL6 and the cyclin-dependent kinase inhibitor, CDKN1A, Transcriptional repressor that may be targeted to the DNA by BCL6; this transcription repressor activity may be related to PKC signaling pathway, Represses CDKN1A expression by binding to its promoter, and this repression is dependent on the retinoic acid response element (RARE element), Promotes cell cycle progression and enhances cell proliferation as well, May have a positive role in tumor cell growth by down-regulating CDKN1A, Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development, PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility, Within the PRC1-like complex, regulates RNF2 ubiquitin ligase activity, Regulates the expression of DPPA4 and NANOG in the NT2 embryonic carcinoma cells


This is RING finger protein unkempt homolog protein, from Dog, contains 810 amino acids, has 5 C3H1-type Zinc finger, has 1 RING-type; degenerate Zinc finger.

RING-type; degenerate

Sequence-specific RNA-binding protein which plays an important role in the establishment and maintenance of the early morphology of cortical neurons during embryonic development, Acts as a translation repressor and controls a translationally regulated cell morphology program to ensure proper structuring of the nervous system, Translational control depends on recognition of its binding element within target mRNAs which consists of a mandatory UAG trimer upstream of a U/A-rich motif, Associated with polysomes


This is Zinc-finger homeodomain protein 9 protein, from Rice, contains 341 amino acids, has 1 ZF-HD dimerization-type; degenerate Zinc finger.

ZF-HD dimerization-type; degenerate


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic protein, from White water-lily, contains 486 amino acids, has 1 C4-type Zinc finger.

Component of the acetyl coenzyme A carboxylase (ACC) complex, Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA


This is Chaperone protein DnaJ protein, from Acholeplasma florum, contains 374 amino acids, has 1 CR-type Zinc finger.

CR-type

Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion, Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex, GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle, Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding, Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins


This is Chaperone protein DnaJ protein, from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1), contains 368 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Formamidopyrimidine-DNA glycosylase protein, from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1), contains 272 amino acids, has 1 FPG-type Zinc finger.

FPG-type

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents, Acts as DNA glycosylase that recognizes and removes damaged bases, Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG), Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand, Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1), contains 298 amino acids, has 1 C4-type Zinc finger.


This is SAGA-associated factor 11 protein, from Yeast, contains 99 amino acids, has 1 SGF11-type Zinc finger.

Functions as component of the transcription regulatory histone acetylation (HAT) complex SAGA, At the promoters, SAGA is required for recruitment of the basal transcription machinery, It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination, SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac), SAGA interacts with DNA via upstream activating sequences (UASs), Involved in transcriptional regulation of a subset of SAGA-regulated genes, Within the SAGA complex, participates in a subcomplex, that specifically deubiquitinates histones H2B


This is PAN2-PAN3 deadenylation complex subunit PAN3 protein, from Yeast, contains 717 amino acids, has 1 C3H1-type Zinc finger.

Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover, PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1, PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex, Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenylation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1, May also be involved in post-transcriptional maturation of mRNA poly(A) tails, PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and with PAB1


This is Structure-specific endonuclease subunit SLX1 protein, from Yeast, contains 312 amino acids, has 1 SLX1-type Zinc finger.

Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination, Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA


This is Pre-mRNA-splicing factor CWC2 protein, from Yeast, contains 306 amino acids, has 1 C3H1-type Zinc finger.

Involved in the first step of pre-mRNA splicing, Required for cell growth and cell cycle control, Plays a role in the levels of the U1, U4, U5 and U6 snRNAs and the maintenance of the U4/U6 snRNA complex, May provide the link between the 'nineteen complex' NTC spliceosome protein complex and the spliceosome through the U6 snRNA, Associates predominantly with U6 snRNAs in assembled active spliceosomes, Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle (By similarity)


This is Negative regulator of PDR1-mediated fluconazole resistance JJJ1 protein, from Yeast, contains 623 amino acids, has 1 C2H2-type Zinc finger.

Acts as a negative regulator of fluconazole resistance, primarily through down-regulation of the ABC transporter gene CDR1 via inactivation of the PDR1 transcriptional pathway


This is N-acetyltransferase ECO1 protein, from Yeast, contains 261 amino acids, has 1 CCHH-type Zinc finger.

CCHH-type

Probable acetyltransferase required for the establishment of sister chromatid cohesion and couple the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together, In contrast to the structural cohesins, the deposition and establishment factors are required only during S phase, Acts by acetylating the cohesin complex component SMC3 (By similarity)

Belongs to the acetyltransferase family, ECO subfamily


This is DNA-directed RNA polymerase II subunit RPB9 protein, from Yeast, contains 122 amino acids, has 1 C4-type Zinc finger, has 1 TFIIS-type Zinc finger.

TFIIS-type

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates, Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs, Pol II is the central component of the basal RNA polymerase II transcription machinery, It is composed of mobile elements that move relative to each other, RPB9 is part of the upper jaw surrounding the central large cleft and thought to grab the incoming DNA template, Involved in the regulation of transcription elongation (By similarity)

Belongs to the archaeal RpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family


This is Chromatin modification-related protein YNG2 protein, from Yeast, contains 274 amino acids, has 1 PHD-type Zinc finger.

PHD-type

Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A, The NuA4 complex is also involved in DNA repair, Involved in cell cycle progression and meiosis (By similarity)


This is Formamidopyrimidine-DNA glycosylase protein, from Rochalimaea quintana, contains 291 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Chaperone protein DnaJ protein, from Rochalimaea quintana, contains 380 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Formamidopyrimidine-DNA glycosylase protein, from Rochalimaea henselae, contains 291 amino acids, has 1 FPG-type Zinc finger.

FPG-type


This is Chaperone protein DnaJ protein, from Rochalimaea henselae, contains 381 amino acids, has 1 CR-type Zinc finger.

CR-type


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Staphylococcus aureus (strain MSSA476), contains 285 amino acids, has 1 C4-type Zinc finger.


This is Chaperone protein DnaJ protein, from Staphylococcus aureus (strain MSSA476), contains 379 amino acids, has 1 CR-type Zinc finger.

CR-type


This is DNA primase protein, from Staphylococcus aureus (strain MSSA476), contains 605 amino acids, has 1 CHC2-type Zinc finger.

RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication


This is UvrABC system protein A protein, from Staphylococcus aureus (strain MSSA476), contains 948 amino acids, has 2 C4-type Zinc finger.

The UvrABC repair system catalyzes the recognition and processing of DNA lesions, UvrA is an ATPase and a DNA-binding protein, A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities, When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Staphylococcus aureus (strain MRSA252), contains 285 amino acids, has 1 C4-type Zinc finger.


This is Chaperone protein DnaJ protein, from Staphylococcus aureus (strain MRSA252), contains 379 amino acids, has 1 CR-type Zinc finger.

CR-type


This is DNA primase protein, from Staphylococcus aureus (strain MRSA252), contains 599 amino acids, has 1 CHC2-type Zinc finger.


This is UvrABC system protein A protein, from Staphylococcus aureus (strain MRSA252), contains 948 amino acids, has 2 C4-type Zinc finger.


This is E3 ubiquitin-protein ligase MARCHF5 protein, from African clawed frog, contains 283 amino acids, has 1 RING-CH-type Zinc finger.

RING-CH-type

Mitochondrial E3 ubiquitin-protein ligase that plays a crucial role in the control of mitochondrial morphology by acting as a positive regulator of mitochondrial fission, May play a role in the prevention of cell senescence acting as a regulator of mitochondrial quality control


This is Nuclear receptor subfamily 2 group C member 1-A protein, from African clawed frog, contains 637 amino acids, has 2 NR C4-type Zinc finger.

NR C4-type

NR C4-type

Orphan nuclear receptor, Binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism, Primarily repressor of a broad range of genes, Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences (By similarity)

Belongs to the nuclear hormone receptor family, NR2 subfamily


This is E3 ubiquitin-protein ligase rnf152-A protein, from African clawed frog, contains 203 amino acids, has 1 RING-type; degenerate Zinc finger.

RING-type; degenerate

E3 ubiquitin-protein ligase mediating 'Lys-63'-linked polyubiquitination of RRAGA in response to amino acid starvation, Thereby, regulates mTORC1 signaling and plays a role in the cellular response to amino acid availability, Also mediates 'Lys-48'-linked polyubiquitination of target proteins and their subsequent targeting to the proteasome for degradation


This is Ubiquitin carboxyl-terminal hydrolase 22-A protein, from African clawed frog, contains 523 amino acids, has 1 UBP-type Zinc finger.

UBP-type

Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA, Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator, Recruited to specific gene promoters by activators, where it is required for transcription (By similarity)

Belongs to the peptidase C19 family, UBP8 subfamily


This is E3 ubiquitin-protein ligase KCMF1 protein, from African clawed frog, contains 381 amino acids, has 1 ZZ-type Zinc finger, has 1 C2H2-type Zinc finger.

ZZ-type

Has intrinsic E3 ubiquitin ligase activity and promotes ubiquitination


This is Histone-lysine N-trimethyltransferase SMYD5 protein, from African clawed frog, contains 421 amino acids, has 1 MYND-type Zinc finger.

MYND-type

Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4 to form trimethylated histone H4 lysine 20 (H4K20me3) which represents a specific tag for epigenetic transcriptional repression

Belongs to the class V-like SAM-binding methyltransferase superfamily


This is Protein Jade-1 protein, from African clawed frog, contains 827 amino acids, has 2 PHD-type Zinc finger, has 1 C2HC pre-PHD-type Zinc finger.

PHD-type

C2HC pre-PHD-type

PHD-type

Scaffold subunit of some HBO1 complexes, which have a histone H4 acetyltransferase activity, Plays a key role in HBO1 complex by directing KAT7/HBO1 specificity towards histone H4 acetylation (H4K5ac, H4K8ac and H4K12ac), regulating DNA replication initiation, regulating DNA replication initiation


This is Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 3 protein, from Mouse, contains 589 amino acids, has 1 Ig-like C2-type Immunoglobulin domain.

Ig-like C2-type


This is Immunoglobulin superfamily containing leucine-rich repeat protein protein, from Mouse, contains 428 amino acids, has 1 Ig-like Immunoglobulin domain.

Ig-like


This is Squamosa promoter-binding-like protein 4 protein, from Rice, contains 251 amino acids, has 1 SBP-type Zinc finger.

SBP-type

Trans-acting factor that binds specifically to the consensus nucleotide sequence 5'-TNCGTACAA-3' (By similarity), May be involved in panicle development


This is Protein YABBY 4 protein, from Rice, contains 256 amino acids, has 1 C4-type Zinc finger.

Seems to be associated with phloem cell differentiation


This is pH-response transcription factor pacC/RIM101 protein, from Corn smut fungus, contains 827 amino acids, has 3 C2H2-type Zinc finger.

Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH, At alkaline ambient pH, activates transcription of alkaline-expressed genes (including pacC itself) and represses transcription of acid-expressed genes (By similarity), Not required for the pH-induced dimorphic transition


This is Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta protein, from Bacillus thuringiensis subsp. konkukian (strain 97-27), contains 289 amino acids, has 1 C4-type Zinc finger.

Component of the acetyl coenzyme A carboxylase (ACC) complex, Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA


This is Formamidopyrimidine-DNA glycosylase protein, from Bacillus thuringiensis subsp. konkukian (strain 97-27), contains 276 amino acids, has 1 FPG-type Zinc finger.

FPG-type

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents, Acts as DNA glycosylase that recognizes and removes damaged bases, Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG), Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand, Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates


This is Chaperone protein DnaJ protein, from Bacillus thuringiensis subsp. konkukian (strain 97-27), contains 371 amino acids, has 1 CR-type Zinc finger.

CR-type

Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion, Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex, GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle, Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding, Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins


This is E3 ubiquitin-protein ligase makorin protein, from Mouse-ear cress, contains 323 amino acids, has 4 C3H1-type Zinc finger, has 1 RING-type Zinc finger.

RING-type

E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins


This is E3 ubiquitin-protein ligase RNF182 protein, from African clawed frog, contains 246 amino acids, has 1 RING-type Zinc finger.

RING-type

E3 ubiquitin-protein ligase that mediates the ubiquitination of atp6v0c and targets it to degradation via the ubiquitin-proteasome pathway


This is Zinc finger protein 770 protein, from Human, contains 691 amino acids, has 10 C2H2-type Zinc finger, has 1 C2H2-type 7; degenerate Zinc finger.

C2H2-type 7; degenerate

May be involved in transcriptional regulation

Belongs to the krueppel C2H2-type zinc-finger protein family


This is RNA-binding protein 4.1 protein, from Zebrafish, contains 419 amino acids, has 1 CCHC-type Zinc finger.

CCHC-type


This is E3 ubiquitin-protein ligase TM129 protein, from African clawed frog, contains 362 amino acids, has 1 RING-type; degenerate Zinc finger.

RING-type; degenerate

E3 ubiquitin-protein ligase involved in ER-associated protein degradation, preferentially associates with the E2 enzyme UBE2J2


This is E3 ubiquitin-protein ligase RNF126-B protein, from African clawed frog, contains 312 amino acids, has 1 C4-type Zinc finger, has 1 RING-type Zinc finger.

RING-type

E3 ubiquitin-protein ligase that mediates ubiquitination oF target proteins, Depending on the associated E2 ligase, mediates 'Lys-48'- and 'Lys-63'-linked polyubiquitination of substrates, Part of a BAG6-dependent quality control process ensuring that proteins of the secretory pathway that are mislocalized to the cytosol are degraded by the proteasome, Probably acts by providing the ubiquitin ligase activity associated with the BAG6 complex and be responsible for ubiquitination of the hydrophobic mislocalized proteins and their targeting to the proteasome


This is RING finger protein Z protein, from MACV, contains 94 amino acids, has 1 RING-type; atypical Zinc finger.

RING-type; atypical

Plays a crucial role in virion assembly and budding, Expressed late in the virus life cycle, it acts as an inhibitor of viral transcription and RNA synthesis by interacting with the viral polymerase L, Presumably recruits the NP encapsidated genome to cellular membranes at budding sites via direct interaction with NP, Plays critical roles in the final steps of viral release by interacting with host TSG101, a member of the vacuolar protein-sorting pathway and using other cellular host proteins involved in vesicle formation pathway, The budding of the virus progeny occurs after association of protein Z with the viral glycoprotein complex SSP-GP1-GP2 at the cell periphery, step that requires myristoylation of protein Z, Also selectively represses protein production by associating with host eIF4E

Belongs to the arenaviridae Z protein family


This is Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 protein, from Rabbit, contains 778 amino acids, has 1 C4-type Zinc finger.

GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6)


This is RING finger protein Z protein, from JUNV, contains 94 amino acids, has 1 RING-type; atypical Zinc finger.

RING-type; atypical


This is E3 ubiquitin-protein ligase RNF166 protein, from Rat, contains 237 amino acids, has 1 RING-type Zinc finger, has 1 C2HC RNF-type Zinc finger.

RING-type

C2HC RNF-type

E3 ubiquitin-protein ligase that promotes the ubiquitination of different substrates, In turn, participates in different biological processes including interferon production or autophagy, Plays a role in the activation of RNA virus-induced interferon-beta production by promoting the ubiquitination of TRAF3 and TRAF6, Also plays a role in the early recruitment of autophagy adapters to bacteria, Mediates 'Lys-29' and 'Lys-33'-linked ubiquitination of SQSTM1 leading to xenophagic targeting of bacteria and inhibition of their replication


This is Zinc finger protein 566 protein, from Chimpanzee, contains 418 amino acids, has 1 C2H2-type 1; degenerate Zinc finger, has 7 C2H2-type Zinc finger.

C2H2-type 1; degenerate


This is Serine/arginine-rich splicing factor RSZ21 protein, from Rice, contains 185 amino acids, has 1 CCHC-type Zinc finger.

CCHC-type


This is Dof zinc finger protein 3 protein, from Rice, contains 373 amino acids, has 1 Dof-type Zinc finger.

Dof-type

Transcriptional activator that binds specifically to the DNA consensus core sequence 5'-AAAG-3' also known as prolamin box (PubMed:16798940), Can activate the expression of genes encoding for the seed storage proteins glutelin, prolamin and globulin, Functions synergistically with RISBZ/BZIP58 to positively regulate quantitatively many seed storage proteins (PubMed:16798940, PubMed:19473328), Functions synergistically with RISBZ1/BZIP58 to positively regulate some metabolic enzymes, such as alanine aminotransferase and pyruvate phosphate dikinase, that are expressed in developing seeds (PubMed:16798940), Functions synergistically with RISBZ1/BZIP58 to positively regulate genes that are key players in the development of aleurone layers (PubMed:19473328), Functions synergistically with RISBZ1/BZIP58 to positively regulate the glutelin GLUD-1 gene in endosperm of developing seeds (PubMed:18980953), Can activate the expression of the bifunctional lysine-degrading enzyme, lysine ketoglutarate reductase/saccharopine dehydrogenase (LKR/SDH), one of the key regulators determining free lysine content in plants (PubMed:21037241), In germinating seeds, involved in the gibberellin-mediated activation of the alpha-amylase AMY1,1/AMY1A gene (PubMed:14500792)


This is Serine/arginine-rich splicing factor RSZ23 protein, from Rice, contains 200 amino acids, has 1 CCHC-type Zinc finger.

CCHC-type

Involved in pre-mRNA splicing, In protoplast assay, enhances splicing efficiency of WAXY intron 1 and alters the selection of the 5'-splice sites by stimulating site 1 (proximal site)