Daily Papers

Anomaly detection in medical images is an important yet challenging task due to the diversity of possible anomalies and the practical impossibility of collecting comprehensively annotated data sets. In this work, we tackle unsupervised medical anomaly detection proposing a modernized autoencoder-based framework, the Q-Former Autoencoder, that leverages state-of-the-art pretrained vision foundation models, such as DINO, DINOv2 and Masked Autoencoder. Instead of training encoders from scratch, we directly utilize frozen vision foundation models as feature extractors, enabling rich, multi-stage, high-level representations without domain-specific fine-tuning. We propose the usage of the Q-Former architecture as the bottleneck, which enables the control of the length of the reconstruction sequence, while efficiently aggregating multiscale features. Additionally, we incorporate a perceptual loss computed using features from a pretrained Masked Autoencoder, guiding the reconstruction towards semantically meaningful structures. Our framework is evaluated on four diverse medical anomaly detection benchmarks, achieving state-of-the-art results on BraTS2021, RESC, and RSNA. Our results highlight the potential of vision foundation model encoders, pretrained on natural images, to generalize effectively to medical image analysis tasks without further fine-tuning. We release the code and models at https://github.com/emirhanbayar/QFAE.

The ability of large language models (LLMs) to follow instructions is crucial for their practical applications, yet the underlying mechanisms remain poorly understood. This paper presents a novel framework that leverages sparse autoencoders (SAE) to interpret how instruction following works in these models. We demonstrate how the features we identify can effectively steer model outputs to align with given instructions. Through analysis of SAE latent activations, we identify specific latents responsible for instruction following behavior. Our findings reveal that instruction following capabilities are encoded by a distinct set of instruction-relevant SAE latents. These latents both show semantic proximity to relevant instructions and demonstrate causal effects on model behavior. Our research highlights several crucial factors for achieving effective steering performance: precise feature identification, the role of final layer, and optimal instruction positioning. Additionally, we demonstrate that our methodology scales effectively across SAEs and LLMs of varying sizes.

Point-cloud based 3D object detectors recently have achieved remarkable progress. However, most studies are limited to the development of network architectures for improving only their accuracy without consideration of the computational efficiency. In this paper, we first propose an autoencoder-style framework comprising channel-wise compression and decompression via interchange transfer-based knowledge distillation. To learn the map-view feature of a teacher network, the features from teacher and student networks are independently passed through the shared autoencoder; here, we use a compressed representation loss that binds the channel-wised compression knowledge from both student and teacher networks as a kind of regularization. The decompressed features are transferred in opposite directions to reduce the gap in the interchange reconstructions. Lastly, we present an head attention loss to match the 3D object detection information drawn by the multi-head self-attention mechanism. Through extensive experiments, we verify that our method can train the lightweight model that is well-aligned with the 3D point cloud detection task and we demonstrate its superiority using the well-known public datasets; e.g., Waymo and nuScenes.

3D generation has witnessed significant advancements, yet efficiently producing high-quality 3D assets from a single image remains challenging. In this paper, we present a triplane autoencoder, which encodes 3D models into a compact triplane latent space to effectively compress both the 3D geometry and texture information. Within the autoencoder framework, we introduce a 3D-aware cross-attention mechanism, which utilizes low-resolution latent representations to query features from a high-resolution 3D feature volume, thereby enhancing the representation capacity of the latent space. Subsequently, we train a diffusion model on this refined latent space. In contrast to solely relying on image embedding for 3D generation, our proposed method advocates for the simultaneous utilization of both image embedding and shape embedding as conditions. Specifically, the shape embedding is estimated via a diffusion prior model conditioned on the image embedding. Through comprehensive experiments, we demonstrate that our method outperforms state-of-the-art algorithms, achieving superior performance while requiring less training data and time. Our approach enables the generation of high-quality 3D assets in merely 7 seconds on a single A100 GPU.

Despite the dominance of convolutional and transformer-based architectures in image-to-image retrieval, these models are prone to biases arising from low-level visual features, such as color. Recognizing the lack of semantic understanding as a key limitation, we propose a novel scene graph-based retrieval framework that emphasizes semantic content over superficial image characteristics. Prior approaches to scene graph retrieval predominantly rely on supervised Graph Neural Networks (GNNs), which require ground truth graph pairs driven from image captions. However, the inconsistency of caption-based supervision stemming from variable text encodings undermine retrieval reliability. To address these, we present SCENIR, a Graph Autoencoder-based unsupervised retrieval framework, which eliminates the dependence on labeled training data. Our model demonstrates superior performance across metrics and runtime efficiency, outperforming existing vision-based, multimodal, and supervised GNN approaches. We further advocate for Graph Edit Distance (GED) as a deterministic and robust ground truth measure for scene graph similarity, replacing the inconsistent caption-based alternatives for the first time in image-to-image retrieval evaluation. Finally, we validate the generalizability of our method by applying it to unannotated datasets via automated scene graph generation, while substantially contributing in advancing state-of-the-art in counterfactual image retrieval.

Massive molecular simulations of drug-target proteins have been used as a tool to understand disease mechanism and develop therapeutics. This work focuses on learning a generative neural network on a structural ensemble of a drug-target protein, e.g. SARS-CoV-2 Spike protein, obtained from computationally expensive molecular simulations. Model tasks involve characterizing the distinct structural fluctuations of the protein bound to various drug molecules, as well as efficient generation of protein conformations that can serve as an complement of a molecular simulation engine. Specifically, we present a geometric autoencoder framework to learn separate latent space encodings of the intrinsic and extrinsic geometries of the protein structure. For this purpose, the proposed Protein Geometric AutoEncoder (ProGAE) model is trained on the protein contact map and the orientation of the backbone bonds of the protein. Using ProGAE latent embeddings, we reconstruct and generate the conformational ensemble of a protein at or near the experimental resolution, while gaining better interpretability and controllability in term of protein structure generation from the learned latent space. Additionally, ProGAE models are transferable to a different state of the same protein or to a new protein of different size, where only the dense layer decoding from the latent representation needs to be retrained. Results show that our geometric learning-based method enjoys both accuracy and efficiency for generating complex structural variations, charting the path toward scalable and improved approaches for analyzing and enhancing high-cost simulations of drug-target proteins.

Driven by improved architectures and better representation learning frameworks, the field of visual recognition has enjoyed rapid modernization and performance boost in the early 2020s. For example, modern ConvNets, represented by ConvNeXt, have demonstrated strong performance in various scenarios. While these models were originally designed for supervised learning with ImageNet labels, they can also potentially benefit from self-supervised learning techniques such as masked autoencoders (MAE). However, we found that simply combining these two approaches leads to subpar performance. In this paper, we propose a fully convolutional masked autoencoder framework and a new Global Response Normalization (GRN) layer that can be added to the ConvNeXt architecture to enhance inter-channel feature competition. This co-design of self-supervised learning techniques and architectural improvement results in a new model family called ConvNeXt V2, which significantly improves the performance of pure ConvNets on various recognition benchmarks, including ImageNet classification, COCO detection, and ADE20K segmentation. We also provide pre-trained ConvNeXt V2 models of various sizes, ranging from an efficient 3.7M-parameter Atto model with 76.7% top-1 accuracy on ImageNet, to a 650M Huge model that achieves a state-of-the-art 88.9% accuracy using only public training data.

Various screening and diagnostic methods have led to a large reduction of cervical cancer death rates in developed countries. However, cervical cancer is the leading cause of cancer related deaths in women in India and other low and middle income countries (LMICs) especially among the urban poor and slum dwellers. Several sophisticated techniques such as cytology tests, HPV tests etc. have been widely used for screening of cervical cancer. These tests are inherently time consuming. In this paper, we propose a convolutional autoencoder based framework, having an architecture similar to SegNet which is trained in an adversarial fashion for classifying images of the cervix acquired using a colposcope. We validate performance on the Intel-Mobile ODT cervical image classification dataset. The proposed method outperforms the standard technique of fine-tuning convolutional neural networks pre-trained on ImageNet database with an average accuracy of 73.75%.

Diffusion models have established themselves as state-of-the-art generative models across various data modalities, including images and videos, due to their ability to accurately approximate complex data distributions. Unlike traditional generative approaches such as VAEs and GANs, diffusion models employ a progressive denoising process that transforms noise into meaningful data over multiple iterative steps. This gradual approach enhances their expressiveness and generation quality. Not only that, diffusion models have also been shown to extract meaningful representations from data while learning to generate samples. Despite their success, the application of diffusion models to graph-structured data remains relatively unexplored, primarily due to the discrete nature of graphs, which necessitates discrete diffusion processes distinct from the continuous methods used in other domains. In this work, we leverage the representational capabilities of diffusion models to learn meaningful embeddings for graph data. By training a discrete diffusion model within an autoencoder framework, we enable both effective autoencoding and representation learning tailored to the unique characteristics of graph-structured data. We only need the encoder at the end to extract representations. Our approach demonstrates the potential of discrete diffusion models to be used for graph representation learning.

Single-cell RNA sequencing (scRNA-seq) data are often confounded by technical or biological batch effects. Existing deep learning models mitigate these effects but often discard batch-specific information, potentially losing valuable biological insights. We propose a Mixed Effects Deep Learning (MEDL) autoencoder framework that separately models batch-invariant (fixed effects) and batch-specific (random effects) components. By decoupling batch-invariant biological states from batch variations, our framework integrates both into predictive models. Our approach also generates 2D visualizations of how the same cell appears across batches, enhancing interpretability. Retaining both fixed and random effect latent spaces improves classification accuracy. We applied our framework to three datasets spanning the cardiovascular system (Healthy Heart), Autism Spectrum Disorder (ASD), and Acute Myeloid Leukemia (AML). With 147 batches in the Healthy Heart dataset, far exceeding typical numbers, we tested our framework's ability to handle many batches. In the ASD dataset, our approach captured donor heterogeneity between autistic and healthy individuals. In the AML dataset, it distinguished donor heterogeneity despite missing cell types and diseased donors exhibiting both healthy and malignant cells. These results highlight our framework's ability to characterize fixed and random effects, enhance batch effect visualization, and improve prediction accuracy across diverse datasets.

In generative modeling, tokenization simplifies complex data into compact, structured representations, creating a more efficient, learnable space. For high-dimensional visual data, it reduces redundancy and emphasizes key features for high-quality generation. Current visual tokenization methods rely on a traditional autoencoder framework, where the encoder compresses data into latent representations, and the decoder reconstructs the original input. In this work, we offer a new perspective by proposing denoising as decoding, shifting from single-step reconstruction to iterative refinement. Specifically, we replace the decoder with a diffusion process that iteratively refines noise to recover the original image, guided by the latents provided by the encoder. We evaluate our approach by assessing both reconstruction (rFID) and generation quality (FID), comparing it to state-of-the-art autoencoding approach. We hope this work offers new insights into integrating iterative generation and autoencoding for improved compression and generation.

Unsupervised pre-training methods for large vision models have shown to enhance performance on downstream supervised tasks. Developing similar techniques for satellite imagery presents significant opportunities as unlabelled data is plentiful and the inherent temporal and multi-spectral structure provides avenues to further improve existing pre-training strategies. In this paper, we present SatMAE, a pre-training framework for temporal or multi-spectral satellite imagery based on Masked Autoencoder (MAE). To leverage temporal information, we include a temporal embedding along with independently masking image patches across time. In addition, we demonstrate that encoding multi-spectral data as groups of bands with distinct spectral positional encodings is beneficial. Our approach yields strong improvements over previous state-of-the-art techniques, both in terms of supervised learning performance on benchmark datasets (up to uparrow 7%), and transfer learning performance on downstream remote sensing tasks, including land cover classification (up to uparrow 14%) and semantic segmentation. Code and data are available on the project website: https://sustainlab-group.github.io/SatMAE/

Geospatial raster data, such as that collected by satellite-based imaging systems at different times and spectral bands, hold immense potential for enabling a wide range of high-impact applications. This potential stems from the rich information that is spatially and temporally contextualized across multiple channels and sensing modalities. Recent work has adapted existing self-supervised learning approaches for such geospatial data. However, they fall short of scalable model architectures, leading to inflexibility and computational inefficiencies when faced with an increasing number of channels and modalities. To address these limitations, we introduce Low-rank Efficient Spatial-Spectral Vision Transformer with three key innovations: i) the LESS Attention Block that approximates high-dimensional spatial-spectral attention through Kronecker's product of the low-dimensional spatial and spectral attention components; ii) the Continuous Positional-Channel Embedding Layer that preserves both the continuity and physical characteristics of each spatial-spectral patch; and iii) the Perception Field Mask that exploits local spatial dependencies by constraining attention to neighboring patches. To evaluate the proposed innovations, we construct GFM-Bench, which serves as a comprehensive benchmark for such geospatial raster data. We pretrain LESS ViT using a Hyperspectral Masked Autoencoder framework with integrated positional and channel masking strategies. Experimental results demonstrate that our proposed method achieves competitive performance against state-of-the-art multi-modal geospatial foundation models while outperforming them on cross-satellite generalization tasks with higher computational efficiency. The flexibility and extensibility of our framework make it a promising direction for future geospatial data analysis tasks that involve a wide range of modalities and channels.

This paper introduces a new interpretation of the Variational Autoencoder framework by taking a fully geometric point of view. We argue that vanilla VAE models unveil naturally a Riemannian structure in their latent space and that taking into consideration those geometrical aspects can lead to better interpolations and an improved generation procedure. This new proposed sampling method consists in sampling from the uniform distribution deriving intrinsically from the learned Riemannian latent space and we show that using this scheme can make a vanilla VAE competitive and even better than more advanced versions on several benchmark datasets. Since generative models are known to be sensitive to the number of training samples we also stress the method's robustness in the low data regime.

Recent advances in large language model-powered multi-agent systems have demonstrated remarkable collective intelligence through effective communication. However, existing approaches face two primary challenges: (i) Ineffective group collaboration modeling, as they rely on pairwise edge representations in graph structures, limiting their ability to capture relationships among multiple agents; and (ii) Limited task-adaptiveness in communication topology design, leading to excessive communication cost for simple tasks and insufficient coordination for complex scenarios. These issues restrict the scalability and practical deployment of adaptive collaboration frameworks. To address these challenges, we propose HyperAgent, a hypergraph-based framework that optimizes communication topologies and effectively captures group collaboration patterns using direct hyperedge representations. Unlike edge-based approaches, HyperAgent uses hyperedges to link multiple agents within the same subtask and employs hypergraph convolutional layers to achieve one-step information aggregation in collaboration groups. Additionally, it incorporates a variational autoencoder framework with sparsity regularization to dynamically adjust hypergraph topologies based on task complexity. Experiments highlight the superiority of HyperAgent in both performance and efficiency. For instance, on GSM8K, HyperAgent achieves 95.07\% accuracy while reducing token consumption by 25.33\%, demonstrating the potential of hypergraph-based optimization for multi-agent communication.

Latent generative models have shown remarkable progress in high-fidelity image synthesis, typically using a two-stage training process that involves compressing images into latent embeddings via learned tokenizers in the first stage. The quality of generation strongly depends on how expressive and well-optimized these latent embeddings are. While various methods have been proposed to learn effective latent representations, generated images often lack realism, particularly in textured regions with sharp transitions, due to loss of fine details governed by high frequencies. We conduct a detailed frequency decomposition of existing state-of-the-art (SOTA) latent tokenizers and show that conventional objectives inherently prioritize low-frequency reconstruction, often at the expense of high-frequency fidelity. Our analysis reveals these latent tokenizers exhibit a bias toward low-frequency information during optimization, leading to over-smoothed outputs and visual artifacts that diminish perceptual quality. To address this, we propose a wavelet-based, frequency-aware variational autoencoder (FA-VAE) framework that explicitly decouples the optimization of low- and high-frequency components. This decoupling enables improved reconstruction of fine textures while preserving global structure. Moreover, we integrate our frequency-preserving latent embeddings into a SOTA latent diffusion model, resulting in sharper and more realistic image generation. Our approach bridges the fidelity gap in current latent tokenizers and emphasizes the importance of frequency-aware optimization for realistic image synthesis, with broader implications for applications in content creation, neural rendering, and medical imaging.

Out-of-distribution (OOD) detection holds significant importance across many applications. While semantic and domain-shift OOD problems are well-studied, this work focuses on covariate shifts - subtle variations in the data distribution that can degrade machine learning performance. We hypothesize that detecting these subtle shifts can improve our understanding of in-distribution boundaries, ultimately improving OOD detection. In adversarial discriminators trained with Batch Normalization (BN), real and adversarial samples form distinct domains with unique batch statistics - a property we exploit for OOD detection. We introduce DisCoPatch, an unsupervised Adversarial Variational Autoencoder (VAE) framework that harnesses this mechanism. During inference, batches consist of patches from the same image, ensuring a consistent data distribution that allows the model to rely on batch statistics. DisCoPatch uses the VAE's suboptimal outputs (generated and reconstructed) as negative samples to train the discriminator, thereby improving its ability to delineate the boundary between in-distribution samples and covariate shifts. By tightening this boundary, DisCoPatch achieves state-of-the-art results in public OOD detection benchmarks. The proposed model not only excels in detecting covariate shifts, achieving 95.5% AUROC on ImageNet-1K(-C) but also outperforms all prior methods on public Near-OOD (95.0%) benchmarks. With a compact model size of 25MB, it achieves high OOD detection performance at notably lower latency than existing methods, making it an efficient and practical solution for real-world OOD detection applications. The code is publicly available.

Humans intuitively perceive object shape and orientation from a single image, guided by strong priors about canonical poses. However, existing 3D generative models often produce misaligned results due to inconsistent training data, limiting their usability in downstream tasks. To address this gap, we introduce the task of orientation-aligned 3D object generation: producing 3D objects from single images with consistent orientations across categories. To facilitate this, we construct Objaverse-OA, a dataset of 14,832 orientation-aligned 3D models spanning 1,008 categories. Leveraging Objaverse-OA, we fine-tune two representative 3D generative models based on multi-view diffusion and 3D variational autoencoder frameworks to produce aligned objects that generalize well to unseen objects across various categories. Experimental results demonstrate the superiority of our method over post-hoc alignment approaches. Furthermore, we showcase downstream applications enabled by our aligned object generation, including zero-shot object orientation estimation via analysis-by-synthesis and efficient arrow-based object rotation manipulation.

Despite progress in audio classification, a generalization gap remains between speech and other sound domains, such as environmental sounds and music. Models trained for speech tasks often fail to perform well on environmental or musical audio tasks, and vice versa. While self-supervised (SSL) audio representations offer an alternative, there has been limited exploration of scaling both model and dataset sizes for SSL-based general audio classification. We introduce Dasheng, a simple SSL audio encoder, based on the efficient masked autoencoder framework. Trained with 1.2 billion parameters on 272,356 hours of diverse audio, Dasheng obtains significant performance gains on the HEAR benchmark. It outperforms previous works on CREMA-D, LibriCount, Speech Commands, VoxLingua, and competes well in music and environment classification. Dasheng features inherently contain rich speech, music, and environmental information, as shown in nearest-neighbor classification experiments. Code is available https://github.com/richermans/dasheng/.

In the domain of medical imaging, many supervised learning based methods for segmentation face several challenges such as high variability in annotations from multiple experts, paucity of labelled data and class imbalanced datasets. These issues may result in segmentations that lack the requisite precision for clinical analysis and can be misleadingly overconfident without associated uncertainty quantification. We propose the PULASki for biomedical image segmentation that accurately captures variability in expert annotations, even in small datasets. Our approach makes use of an improved loss function based on statistical distances in a conditional variational autoencoder structure (Probabilistic UNet), which improves learning of the conditional decoder compared to the standard cross-entropy particularly in class imbalanced problems. We analyse our method for two structurally different segmentation tasks (intracranial vessel and multiple sclerosis (MS) lesion) and compare our results to four well-established baselines in terms of quantitative metrics and qualitative output. Empirical results demonstrate the PULASKi method outperforms all baselines at the 5\% significance level. The generated segmentations are shown to be much more anatomically plausible than in the 2D case, particularly for the vessel task. Our method can also be applied to a wide range of multi-label segmentation tasks and and is useful for downstream tasks such as hemodynamic modelling (computational fluid dynamics and data assimilation), clinical decision making, and treatment planning.

The proliferation of audio deepfakes poses a growing threat to trust in digital communications. While detection methods have advanced, attributing audio deepfakes to their source models remains an underexplored yet crucial challenge. In this paper we introduce LAVA (Layered Architecture for Voice Attribution), a hierarchical framework for audio deepfake detection and model recognition that leverages attention-enhanced latent representations extracted by a convolutional autoencoder trained solely on fake audio. Two specialized classifiers operate on these features: Audio Deepfake Attribution (ADA), which identifies the generation technology, and Audio Deepfake Model Recognition (ADMR), which recognize the specific generative model instance. To improve robustness under open-set conditions, we incorporate confidence-based rejection thresholds. Experiments on ASVspoof2021, FakeOrReal, and CodecFake show strong performance: the ADA classifier achieves F1-scores over 95% across all datasets, and the ADMR module reaches 96.31% macro F1 across six classes. Additional tests on unseen attacks from ASVpoof2019 LA and error propagation analysis confirm LAVA's robustness and reliability. The framework advances the field by introducing a supervised approach to deepfake attribution and model recognition under open-set conditions, validated on public benchmarks and accompanied by publicly released models and code. Models and code are available at https://www.github.com/adipiz99/lava-framework.

In recent years, exploiting the domain-specific underlying structure of data and its generative factors for representation learning has shown success in various use-case agnostic applications. However, the diversity and complexity of tabular data have made it challenging to represent these structures in a latent space through multi-dimensional vectors. We design an autoencoder-based framework for building general purpose embeddings, we assess the performance of different autoencoder architectures, and show simpler models outperform complex ones in embedding highly complex tabular data. We apply our framework to produce plug-and-play, rich, and anonymized embeddings representing AWS customers for usage in any model, saving up to 45% of development time, and observe significant improvements in downstream models. Moreover, we propose a significant improvement to the calculation of reconstruction loss for multi-layer contractive autoencoders (CAE) by calculating the Jacobian of the entire encoder leading to a 15% improvement in reconstruction quality when compared to a stacked CAE.

We introduce a graph-aware autoencoder ensemble framework, with associated formalisms and tooling, designed to facilitate deep learning for scholarship in the humanities. By composing sub-architectures to produce a model isomorphic to a humanistic domain we maintain interpretability while providing function signatures for each sub-architectural choice, allowing both traditional and computational researchers to collaborate without disrupting established practices. We illustrate a practical application of our approach to a historical study of the American post-Atlantic slave trade, and make several specific technical contributions: a novel hybrid graph-convolutional autoencoder mechanism, batching policies for common graph topologies, and masking techniques for particular use-cases. The effectiveness of the framework for broadening participation of diverse domains is demonstrated by a growing suite of two dozen studies, both collaborations with humanists and established tasks from machine learning literature, spanning a variety of fields and data modalities. We make performance comparisons of several different architectural choices and conclude with an ambitious list of imminent next steps for this research.

The growing volume of high-resolution Whole Slide Images in digital histopathology poses significant storage, transmission, and computational efficiency challenges. Standard compression methods, such as JPEG, reduce file sizes but often fail to preserve fine-grained phenotypic details critical for downstream tasks. In this work, we repurpose autoencoders (AEs) designed for Latent Diffusion Models as an efficient learned compression framework for pathology images. We systematically benchmark three AE models with varying compression levels and evaluate their reconstruction ability using pathology foundation models. We introduce a fine-tuning strategy to further enhance reconstruction fidelity that optimizes a pathology-specific learned perceptual metric. We validate our approach on downstream tasks, including segmentation, patch classification, and multiple instance learning, showing that replacing images with AE-compressed reconstructions leads to minimal performance degradation. Additionally, we propose a K-means clustering-based quantization method for AE latents, improving storage efficiency while maintaining reconstruction quality. We provide the weights of the fine-tuned autoencoders at https://huggingface.co/collections/StonyBrook-CVLab/pathology-fine-tuned-aes-67d45f223a659ff2e3402dd0.

Prosody plays an important role in characterizing the style of a speaker or an emotion, but most non-parallel voice or emotion style transfer algorithms do not convert any prosody information. Two major components of prosody are pitch and rhythm. Disentangling the prosody information, particularly the rhythm component, from the speech is challenging because it involves breaking the synchrony between the input speech and the disentangled speech representation. As a result, most existing prosody style transfer algorithms would need to rely on some form of text transcriptions to identify the content information, which confines their application to high-resource languages only. Recently, SpeechSplit has made sizeable progress towards unsupervised prosody style transfer, but it is unable to extract high-level global prosody style in an unsupervised manner. In this paper, we propose AutoPST, which can disentangle global prosody style from speech without relying on any text transcriptions. AutoPST is an Autoencoder-based Prosody Style Transfer framework with a thorough rhythm removal module guided by the self-expressive representation learning. Experiments on different style transfer tasks show that AutoPST can effectively convert prosody that correctly reflects the styles of the target domains.

The variational autoencoder (VAE) framework is a popular option for training unsupervised generative models, featuring ease of training and latent representation of data. The objective function of VAE does not guarantee to achieve the latter, however, and failure to do so leads to a frequent failure mode called posterior collapse. Even in successful cases, VAEs often result in low-precision reconstructions and generated samples. The introduction of the KL-divergence weight beta can help steer the model clear of posterior collapse, but its tuning is often a trial-and-error process with no guiding metrics. Here we test the idea of using the total VAE loss of generated samples (generated loss) as the proxy metric for generation quality, the related hypothesis that VAE reconstruction from the mean latent vector tends to be a more typical example of its class than the original, and the idea of exploiting this property by augmenting training data with generated variants (augmented training). The results are mixed, but repeated encoding and decoding indeed result in qualitatively and quantitatively more typical examples from both convolutional and fully-connected MNIST VAEs, suggesting that it may be an inherent property of the VAE framework.

The variational autoencoder (VAE) framework remains a popular option for training unsupervised generative models, especially for discrete data where generative adversarial networks (GANs) require workaround to create gradient for the generator. In our work modeling US postal addresses, we show that our discrete VAE with tree recursive architecture demonstrates limited capability of capturing field correlations within structured data, even after overcoming the challenge of posterior collapse with scheduled sampling and tuning of the KL-divergence weight beta. Worse, VAE seems to have difficulty mapping its generated samples to the latent space, as their VAE loss lags behind or even increases during the training process. Motivated by this observation, we show that augmenting training data with generated variants (augmented training) and training a VAE with multiple values of beta simultaneously (multiscale VAE) both improve the generation quality of VAE. Despite their differences in motivation and emphasis, we show that augmented training and multiscale VAE are actually connected and have similar effects on the model.

Autoregressive models have demonstrated remarkable success across various fields, from large language models (LLMs) to large multimodal models (LMMs) and 2D content generation, moving closer to artificial general intelligence (AGI). Despite these advances, applying autoregressive approaches to 3D object generation and understanding remains largely unexplored. This paper introduces Scale AutoRegressive 3D (SAR3D), a novel framework that leverages a multi-scale 3D vector-quantized variational autoencoder (VQVAE) to tokenize 3D objects for efficient autoregressive generation and detailed understanding. By predicting the next scale in a multi-scale latent representation instead of the next single token, SAR3D reduces generation time significantly, achieving fast 3D object generation in just 0.82 seconds on an A6000 GPU. Additionally, given the tokens enriched with hierarchical 3D-aware information, we finetune a pretrained LLM on them, enabling multimodal comprehension of 3D content. Our experiments show that SAR3D surpasses current 3D generation methods in both speed and quality and allows LLMs to interpret and caption 3D models comprehensively.

Structural topology optimization (TO) is central to engineering design but remains computationally intensive due to complex physics and hard constraints. Existing deep-learning methods are limited to fixed square grids, a few hand-coded boundary conditions, and post-hoc optimization, preventing general deployment. We introduce Optimize Any Topology (OAT), a foundation-model framework that directly predicts minimum-compliance layouts for arbitrary aspect ratios, resolutions, volume fractions, loads, and fixtures. OAT combines a resolution- and shape-agnostic autoencoder with an implicit neural-field decoder and a conditional latent-diffusion model trained on OpenTO, a new corpus of 2.2 million optimized structures covering 2 million unique boundary-condition configurations. On four public benchmarks and two challenging unseen tests, OAT lowers mean compliance up to 90% relative to the best prior models and delivers sub-1 second inference on a single GPU across resolutions from 64 x 64 to 256 x 256 and aspect ratios as high as 10:1. These results establish OAT as a general, fast, and resolution-free framework for physics-aware topology optimization and provide a large-scale dataset to spur further research in generative modeling for inverse design. Code & data can be found at https://github.com/ahnobari/OptimizeAnyTopology.

We frame the problem of unifying representations in neural models as one of sparse model recovery and introduce a framework that extends sparse autoencoders (SAEs) to lifted spaces and infinite-dimensional function spaces, enabling mechanistic interpretability of large neural operators (NO). While the Platonic Representation Hypothesis suggests that neural networks converge to similar representations across architectures, the representational properties of neural operators remain underexplored despite their growing importance in scientific computing. We compare the inference and training dynamics of SAEs, lifted-SAE, and SAE neural operators. We highlight how lifting and operator modules introduce beneficial inductive biases, enabling faster recovery, improved recovery of smooth concepts, and robust inference across varying resolutions, a property unique to neural operators.

Sparse Autoencoders (SAEs) provide potentials for uncovering structured, human-interpretable representations in Large Language Models (LLMs), making them a crucial tool for transparent and controllable AI systems. We systematically analyze SAE for interpretable feature extraction from LLMs in safety-critical classification tasks. Our framework evaluates (1) model-layer selection and scaling properties, (2) SAE architectural configurations, including width and pooling strategies, and (3) the effect of binarizing continuous SAE activations. SAE-derived features achieve macro F1 > 0.8, outperforming hidden-state and BoW baselines while demonstrating cross-model transfer from Gemma 2 2B to 9B-IT models. These features generalize in a zero-shot manner to cross-lingual toxicity detection and visual classification tasks. Our analysis highlights the significant impact of pooling strategies and binarization thresholds, showing that binarization offers an efficient alternative to traditional feature selection while maintaining or improving performance. These findings establish new best practices for SAE-based interpretability and enable scalable, transparent deployment of LLMs in real-world applications. Full repo: https://github.com/shan23chen/MOSAIC.

This paper proposes a self-supervised approach to learn universal facial representations from videos, that can transfer across a variety of facial analysis tasks such as Facial Attribute Recognition (FAR), Facial Expression Recognition (FER), DeepFake Detection (DFD), and Lip Synchronization (LS). Our proposed framework, named MARLIN, is a facial video masked autoencoder, that learns highly robust and generic facial embeddings from abundantly available non-annotated web crawled facial videos. As a challenging auxiliary task, MARLIN reconstructs the spatio-temporal details of the face from the densely masked facial regions which mainly include eyes, nose, mouth, lips, and skin to capture local and global aspects that in turn help in encoding generic and transferable features. Through a variety of experiments on diverse downstream tasks, we demonstrate MARLIN to be an excellent facial video encoder as well as feature extractor, that performs consistently well across a variety of downstream tasks including FAR (1.13% gain over supervised benchmark), FER (2.64% gain over unsupervised benchmark), DFD (1.86% gain over unsupervised benchmark), LS (29.36% gain for Frechet Inception Distance), and even in low data regime. Our code and models are available at https://github.com/ControlNet/MARLIN .

Text-to-image (T2I) diffusion models have achieved remarkable progress in generating high-quality images but also raise people's concerns about generating harmful or misleading content. While extensive approaches have been proposed to erase unwanted concepts without requiring retraining from scratch, they inadvertently degrade performance on normal generation tasks. In this work, we propose Interpret then Deactivate (ItD), a novel framework to enable precise concept removal in T2I diffusion models while preserving overall performance. ItD first employs a sparse autoencoder (SAE) to interpret each concept as a combination of multiple features. By permanently deactivating the specific features associated with target concepts, we repurpose SAE as a zero-shot classifier that identifies whether the input prompt includes target concepts, allowing selective concept erasure in diffusion models. Moreover, we demonstrate that ItD can be easily extended to erase multiple concepts without requiring further training. Comprehensive experiments across celebrity identities, artistic styles, and explicit content demonstrate ItD's effectiveness in eliminating targeted concepts without interfering with normal concept generation. Additionally, ItD is also robust against adversarial prompts designed to circumvent content filters. Code is available at: https://github.com/NANSirun/Interpret-then-deactivate.

Masked graph autoencoders have emerged as a powerful graph self-supervised learning method that has yet to be fully explored. In this paper, we unveil that the existing discrete edge masking and binary link reconstruction strategies are insufficient to learn topologically informative representations, from the perspective of message propagation on graph neural networks. These limitations include blocking message flows, vulnerability to over-smoothness, and suboptimal neighborhood discriminability. Inspired by these understandings, we explore non-discrete edge masks, which are sampled from a continuous and dispersive probability distribution instead of the discrete Bernoulli distribution. These masks restrict the amount of output messages for each edge, referred to as "bandwidths". We propose a novel, informative, and effective topological masked graph autoencoder using bandwidth masking and a layer-wise bandwidth prediction objective. We demonstrate its powerful graph topological learning ability both theoretically and empirically. Our proposed framework outperforms representative baselines in both self-supervised link prediction (improving the discrete edge reconstructors by at most 20%) and node classification on numerous datasets, solely with a structure-learning pretext. Our implementation is available at https://github.com/Newiz430/Bandana.

Recognizing the prevalence of domain shift as a common challenge in machine learning, various domain generalization (DG) techniques have been developed to enhance the performance of machine learning systems when dealing with out-of-distribution (OOD) data. Furthermore, in real-world scenarios, data distributions can gradually change across a sequence of sequential domains. While current methodologies primarily focus on improving model effectiveness within these new domains, they often overlook fairness issues throughout the learning process. In response, we introduce an innovative framework called Counterfactual Fairness-Aware Domain Generalization with Sequential Autoencoder (CDSAE). This approach effectively separates environmental information and sensitive attributes from the embedded representation of classification features. This concurrent separation not only greatly improves model generalization across diverse and unfamiliar domains but also effectively addresses challenges related to unfair classification. Our strategy is rooted in the principles of causal inference to tackle these dual issues. To examine the intricate relationship between semantic information, sensitive attributes, and environmental cues, we systematically categorize exogenous uncertainty factors into four latent variables: 1) semantic information influenced by sensitive attributes, 2) semantic information unaffected by sensitive attributes, 3) environmental cues influenced by sensitive attributes, and 4) environmental cues unaffected by sensitive attributes. By incorporating fairness regularization, we exclusively employ semantic information for classification purposes. Empirical validation on synthetic and real-world datasets substantiates the effectiveness of our approach, demonstrating improved accuracy levels while ensuring the preservation of fairness in the evolving landscape of continuous domains.

Reducing inference time and energy usage while maintaining prediction accuracy has become a significant concern for deep neural networks (DNN) inference on resource-constrained edge devices. To address this problem, we propose a novel approach based on "converting" autoencoder and lightweight DNNs. This improves upon recent work such as early-exiting framework and DNN partitioning. Early-exiting frameworks spend different amounts of computation power for different input data depending upon their complexity. However, they can be inefficient in real-world scenarios that deal with many hard image samples. On the other hand, DNN partitioning algorithms that utilize the computation power of both the cloud and edge devices can be affected by network delays and intermittent connections between the cloud and the edge. We present CBNet, a low-latency and energy-efficient DNN inference framework tailored for edge devices. It utilizes a "converting" autoencoder to efficiently transform hard images into easy ones, which are subsequently processed by a lightweight DNN for inference. To the best of our knowledge, such autoencoder has not been proposed earlier. Our experimental results using three popular image-classification datasets on a Raspberry Pi 4, a Google Cloud instance, and an instance with Nvidia Tesla K80 GPU show that CBNet achieves up to 4.8x speedup in inference latency and 79% reduction in energy usage compared to competing techniques while maintaining similar or higher accuracy.

We introduce DC-VideoGen, a post-training acceleration framework for efficient video generation. DC-VideoGen can be applied to any pre-trained video diffusion model, improving efficiency by adapting it to a deep compression latent space with lightweight fine-tuning. The framework builds on two key innovations: (i) a Deep Compression Video Autoencoder with a novel chunk-causal temporal design that achieves 32x/64x spatial and 4x temporal compression while preserving reconstruction quality and generalization to longer videos; and (ii) AE-Adapt-V, a robust adaptation strategy that enables rapid and stable transfer of pre-trained models into the new latent space. Adapting the pre-trained Wan-2.1-14B model with DC-VideoGen requires only 10 GPU days on the NVIDIA H100 GPU. The accelerated models achieve up to 14.8x lower inference latency than their base counterparts without compromising quality, and further enable 2160x3840 video generation on a single GPU. Code: https://github.com/dc-ai-projects/DC-VideoGen.

Recent video masked autoencoder (MAE) works have designed improved masking algorithms focused on saliency. These works leverage visual cues such as motion to mask the most salient regions. However, the robustness of such visual cues depends on how often input videos match underlying assumptions. On the other hand, natural language description is an information dense representation of video that implicitly captures saliency without requiring modality-specific assumptions, and has not been explored yet for video MAE. To this end, we introduce a novel text-guided masking algorithm (TGM) that masks the video regions with highest correspondence to paired captions. Without leveraging any explicit visual cues for saliency, our TGM is competitive with state-of-the-art masking algorithms such as motion-guided masking. To further benefit from the semantics of natural language for masked reconstruction, we next introduce a unified framework for joint MAE and masked video-text contrastive learning. We show that across existing masking algorithms, unifying MAE and masked video-text contrastive learning improves downstream performance compared to pure MAE on a variety of video recognition tasks, especially for linear probe. Within this unified framework, our TGM achieves the best relative performance on five action recognition and one egocentric datasets, highlighting the complementary nature of natural language for masked video modeling.

Anomaly detection in 12-lead electrocardiograms (ECGs) is critical for identifying deviations associated with cardiovascular disease. This work presents a comparative analysis of three autoencoder-based architectures: convolutional autoencoder (CAE), variational autoencoder with bidirectional long short-term memory (VAE-BiLSTM), and VAE-BiLSTM with multi-head attention (VAE-BiLSTM-MHA), for unsupervised anomaly detection in ECGs. To the best of our knowledge, this study reports the first application of a VAE-BiLSTM-MHA architecture to ECG anomaly detection. All models are trained on normal ECG samples to reconstruct non-anomalous cardiac morphology and detect deviations indicative of disease. Using a unified preprocessing and evaluation pipeline on the public China Physiological Signal Challenge (CPSC) dataset, the attention-augmented VAE achieves the best performance, with an AUPRC of 0.81 and a recall of 0.85 on the held-out test set, outperforming the other architectures. To support clinical triage, this model is further integrated into an interactive dashboard that visualizes anomaly localization. In addition, a performance comparison with baseline models from the literature is provided.

Skeleton sequence representation learning has shown great advantages for action recognition due to its promising ability to model human joints and topology. However, the current methods usually require sufficient labeled data for training computationally expensive models, which is labor-intensive and time-consuming. Moreover, these methods ignore how to utilize the fine-grained dependencies among different skeleton joints to pre-train an efficient skeleton sequence learning model that can generalize well across different datasets. In this paper, we propose an efficient skeleton sequence learning framework, named Skeleton Sequence Learning (SSL). To comprehensively capture the human pose and obtain discriminative skeleton sequence representation, we build an asymmetric graph-based encoder-decoder pre-training architecture named SkeletonMAE, which embeds skeleton joint sequence into Graph Convolutional Network (GCN) and reconstructs the masked skeleton joints and edges based on the prior human topology knowledge. Then, the pre-trained SkeletonMAE encoder is integrated with the Spatial-Temporal Representation Learning (STRL) module to build the SSL framework. Extensive experimental results show that our SSL generalizes well across different datasets and outperforms the state-of-the-art self-supervised skeleton-based action recognition methods on FineGym, Diving48, NTU 60 and NTU 120 datasets. Additionally, we obtain comparable performance to some fully supervised methods. The code is avaliable at https://github.com/HongYan1123/SkeletonMAE.

Non-parallel many-to-many voice conversion remains an interesting but challenging speech processing task. Recently, AutoVC, a conditional autoencoder based method, achieved excellent conversion results by disentangling the speaker identity and the speech content using information-constraining bottlenecks. However, due to the pure autoencoder training method, it is difficult to evaluate the separation effect of content and speaker identity. In this paper, a novel voice conversion framework, named boldsymbol Text boldsymbol Guided boldsymbol AutoVC(TGAVC), is proposed to more effectively separate content and timbre from speech, where an expected content embedding produced based on the text transcriptions is designed to guide the extraction of voice content. In addition, the adversarial training is applied to eliminate the speaker identity information in the estimated content embedding extracted from speech. Under the guidance of the expected content embedding and the adversarial training, the content encoder is trained to extract speaker-independent content embedding from speech. Experiments on AIShell-3 dataset show that the proposed model outperforms AutoVC in terms of naturalness and similarity of converted speech.

3D characters are essential to modern creative industries, but making them animatable often demands extensive manual work in tasks like rigging and skinning. Existing automatic rigging tools face several limitations, including the necessity for manual annotations, rigid skeleton topologies, and limited generalization across diverse shapes and poses. An alternative approach is to generate animatable avatars pre-bound to a rigged template mesh. However, this method often lacks flexibility and is typically limited to realistic human shapes. To address these issues, we present Make-It-Animatable, a novel data-driven method to make any 3D humanoid model ready for character animation in less than one second, regardless of its shapes and poses. Our unified framework generates high-quality blend weights, bones, and pose transformations. By incorporating a particle-based shape autoencoder, our approach supports various 3D representations, including meshes and 3D Gaussian splats. Additionally, we employ a coarse-to-fine representation and a structure-aware modeling strategy to ensure both accuracy and robustness, even for characters with non-standard skeleton structures. We conducted extensive experiments to validate our framework's effectiveness. Compared to existing methods, our approach demonstrates significant improvements in both quality and speed.

This report presents a comprehensive framework for generating high-quality 3D shapes and textures from diverse input prompts, including single images, multi-view images, and text descriptions. The framework consists of 3D shape generation and texture generation. (1). The 3D shape generation pipeline employs a Variational Autoencoder (VAE) to encode implicit 3D geometries into a latent space and a diffusion network to generate latents conditioned on input prompts, with modifications to enhance model capacity. An alternative Artist-Created Mesh (AM) generation approach is also explored, yielding promising results for simpler geometries. (2). Texture generation involves a multi-stage process starting with frontal images generation followed by multi-view images generation, RGB-to-PBR texture conversion, and high-resolution multi-view texture refinement. A consistency scheduler is plugged into every stage, to enforce pixel-wise consistency among multi-view textures during inference, ensuring seamless integration. The pipeline demonstrates effective handling of diverse input formats, leveraging advanced neural architectures and novel methodologies to produce high-quality 3D content. This report details the system architecture, experimental results, and potential future directions to improve and expand the framework. The source code and pretrained weights are released at: https://github.com/Tencent/Tencent-XR-3DGen.

Semiconductor lasers, one of the key components for optical communication systems, have been rapidly evolving to meet the requirements of next generation optical networks with respect to high speed, low power consumption, small form factor etc. However, these demands have brought severe challenges to the semiconductor laser reliability. Therefore, a great deal of attention has been devoted to improving it and thereby ensuring reliable transmission. In this paper, a predictive maintenance framework using machine learning techniques is proposed for real-time heath monitoring and prognosis of semiconductor laser and thus enhancing its reliability. The proposed approach is composed of three stages: i) real-time performance degradation prediction, ii) degradation detection, and iii) remaining useful life (RUL) prediction. First of all, an attention based gated recurrent unit (GRU) model is adopted for real-time prediction of performance degradation. Then, a convolutional autoencoder is used to detect the degradation or abnormal behavior of a laser, given the predicted degradation performance values. Once an abnormal state is detected, a RUL prediction model based on attention-based deep learning is utilized. Afterwards, the estimated RUL is input for decision making and maintenance planning. The proposed framework is validated using experimental data derived from accelerated aging tests conducted for semiconductor tunable lasers. The proposed approach achieves a very good degradation performance prediction capability with a small root mean square error (RMSE) of 0.01, a good anomaly detection accuracy of 94.24% and a better RUL estimation capability compared to the existing ML-based laser RUL prediction models.

Audio-Visual Emotion Recognition (AVER) has garnered increasing attention in recent years for its critical role in creating emotion-ware intelligent machines. Previous efforts in this area are dominated by the supervised learning paradigm. Despite significant progress, supervised learning is meeting its bottleneck due to the longstanding data scarcity issue in AVER. Motivated by recent advances in self-supervised learning, we propose Hierarchical Contrastive Masked Autoencoder (HiCMAE), a novel self-supervised framework that leverages large-scale self-supervised pre-training on vast unlabeled audio-visual data to promote the advancement of AVER. Following prior arts in self-supervised audio-visual representation learning, HiCMAE adopts two primary forms of self-supervision for pre-training, namely masked data modeling and contrastive learning. Unlike them which focus exclusively on top-layer representations while neglecting explicit guidance of intermediate layers, HiCMAE develops a three-pronged strategy to foster hierarchical audio-visual feature learning and improve the overall quality of learned representations. To verify the effectiveness of HiCMAE, we conduct extensive experiments on 9 datasets covering both categorical and dimensional AVER tasks. Experimental results show that our method significantly outperforms state-of-the-art supervised and self-supervised audio-visual methods, which indicates that HiCMAE is a powerful audio-visual emotion representation learner. Codes and models will be publicly available at https://github.com/sunlicai/HiCMAE.

The rapid and accurate detection of COVID-19 cases is critical for timely treatment and preventing the spread of the disease. In this study, a two-stage feature extraction framework using eight state-of-the-art pre-trained deep Convolutional Neural Networks (CNNs) and an autoencoder is proposed to determine the health conditions of patients (COVID-19, Normal, Viral Pneumonia) based on chest X-rays. The X-ray scans are divided into four equally sized sections and analyzed by deep pre-trained CNNs. Subsequently, an autoencoder with three hidden layers is trained to extract reproductive features from the concatenated ouput of CNNs. To evaluate the performance of the proposed framework, three different classifiers, which are single-layer perceptron (SLP), multi-layer perceptron (MLP), and support vector machine (SVM) are used. Furthermore, the deep CNN architectures are used to create benchmark models and trained on the same dataset for comparision. The proposed framework outperforms other frameworks wih pre-trained feature extractors in binary classification and shows competitive results in three-class classification. The proposed methodology is task-independent and suitable for addressing various problems. The results show that the discriminative features are a subset of the reproductive features, suggesting that extracting task-independent features is superior to the extraction only task-based features. The flexibility and task-independence of the reproductive features make the conceptive information approach more favorable. The proposed methodology is novel and shows promising results for analyzing medical image data.

Video-language pre-training is crucial for learning powerful multi-modal representation. However, it typically requires a massive amount of computation. In this paper, we develop SMAUG, an efficient pre-training framework for video-language models. The foundation component in SMAUG is masked autoencoders. Different from prior works which only mask textual inputs, our masking strategy considers both visual and textual modalities, providing a better cross-modal alignment and saving more pre-training costs. On top of that, we introduce a space-time token sparsification module, which leverages context information to further select only "important" spatial regions and temporal frames for pre-training. Coupling all these designs allows our method to enjoy both competitive performances on text-to-video retrieval and video question answering tasks, and much less pre-training costs by 1.9X or more. For example, our SMAUG only needs about 50 NVIDIA A6000 GPU hours for pre-training to attain competitive performances on these two video-language tasks across six popular benchmarks.

In this paper, we propose Multiresolution Equivariant Graph Variational Autoencoders (MGVAE), the first hierarchical generative model to learn and generate graphs in a multiresolution and equivariant manner. At each resolution level, MGVAE employs higher order message passing to encode the graph while learning to partition it into mutually exclusive clusters and coarsening into a lower resolution that eventually creates a hierarchy of latent distributions. MGVAE then constructs a hierarchical generative model to variationally decode into a hierarchy of coarsened graphs. Importantly, our proposed framework is end-to-end permutation equivariant with respect to node ordering. MGVAE achieves competitive results with several generative tasks including general graph generation, molecular generation, unsupervised molecular representation learning to predict molecular properties, link prediction on citation graphs, and graph-based image generation.

Accent plays a significant role in speech communication, influencing one's capability to understand as well as conveying a person's identity. This paper introduces a novel and efficient framework for accented Text-to-Speech (TTS) synthesis based on a Conditional Variational Autoencoder. It has the ability to synthesize a selected speaker's voice, and convert this to any desired target accent. Our thorough experiments validate the effectiveness of the proposed framework using both objective and subjective evaluations. The results also show remarkable performance in terms of the model's ability to manipulate accents in the synthesized speech. Overall, our proposed framework presents a promising avenue for future accented TTS research.

"If I provide you a face image of mine (without telling you the actual age when I took the picture) and a large amount of face images that I crawled (containing labeled faces of different ages but not necessarily paired), can you show me what I would look like when I am 80 or what I was like when I was 5?" The answer is probably a "No." Most existing face aging works attempt to learn the transformation between age groups and thus would require the paired samples as well as the labeled query image. In this paper, we look at the problem from a generative modeling perspective such that no paired samples is required. In addition, given an unlabeled image, the generative model can directly produce the image with desired age attribute. We propose a conditional adversarial autoencoder (CAAE) that learns a face manifold, traversing on which smooth age progression and regression can be realized simultaneously. In CAAE, the face is first mapped to a latent vector through a convolutional encoder, and then the vector is projected to the face manifold conditional on age through a deconvolutional generator. The latent vector preserves personalized face features (i.e., personality) and the age condition controls progression vs. regression. Two adversarial networks are imposed on the encoder and generator, respectively, forcing to generate more photo-realistic faces. Experimental results demonstrate the appealing performance and flexibility of the proposed framework by comparing with the state-of-the-art and ground truth.

Self-supervised learning (SSL) has demonstrated remarkable success in 3D point cloud analysis, particularly through masked autoencoders (MAEs). However, existing MAE-based methods lack rotation invariance, leading to significant performance degradation when processing arbitrarily rotated point clouds in real-world scenarios. To address this limitation, we introduce Handcrafted Feature-Based Rotation-Invariant Masked Autoencoder (HFBRI-MAE), a novel framework that refines the MAE design with rotation-invariant handcrafted features to ensure stable feature learning across different orientations. By leveraging both rotation-invariant local and global features for token embedding and position embedding, HFBRI-MAE effectively eliminates rotational dependencies while preserving rich geometric structures. Additionally, we redefine the reconstruction target to a canonically aligned version of the input, mitigating rotational ambiguities. Extensive experiments on ModelNet40, ScanObjectNN, and ShapeNetPart demonstrate that HFBRI-MAE consistently outperforms existing methods in object classification, segmentation, and few-shot learning, highlighting its robustness and strong generalization ability in real-world 3D applications.

We introduce ReALLM, a novel approach for compression and memory-efficient adaptation of pre-trained language models that encompasses most of the post-training quantization and fine-tuning methods for a budget of <4 bits. Pre-trained matrices are decomposed into a high-precision low-rank component and a vector-quantized latent representation (using an autoencoder). During the fine-tuning step, only the low-rank components are updated. Our results show that pre-trained matrices exhibit different patterns. ReALLM adapts the shape of the encoder (small/large embedding, high/low bit VQ, etc.) to each matrix. ReALLM proposes to represent each matrix with a small embedding on b bits and a neural decoder model D_phi with its weights on b_phi bits. The decompression of a matrix requires only one embedding and a single forward pass with the decoder. Our weight-only quantization algorithm yields the best results on language generation tasks (C4 and WikiText-2) for a budget of 3 bits without any training. With a budget of 2 bits, ReALLM achieves state-of-the art performance after fine-tuning on a small calibration dataset.

Transcriptomic foundation models (TFMs) have recently emerged as powerful tools for analyzing gene expression in cells and tissues, supporting key tasks such as cell-type annotation, batch correction, and perturbation prediction. However, the diversity of model implementations and training strategies across recent TFMs, though promising, makes it challenging to isolate the contribution of individual design choices or evaluate their potential synergies. This hinders the field's ability to converge on best practices and limits the reproducibility of insights across studies. We present BMFM-RNA, an open-source, modular software package that unifies diverse TFM pretraining and fine-tuning objectives within a single framework. Leveraging this capability, we introduce a novel training objective, whole cell expression decoder (WCED), which captures global expression patterns using an autoencoder-like CLS bottleneck representation. In this paper, we describe the framework, supported input representations, and training objectives. We evaluated four model checkpoints pretrained on CELLxGENE using combinations of masked language modeling (MLM), WCED and multitask learning. Using the benchmarking capabilities of BMFM-RNA, we show that WCED-based models achieve performance that matches or exceeds state-of-the-art approaches like scGPT across more than a dozen datasets in both zero-shot and fine-tuning tasks. BMFM-RNA, available as part of the biomed-multi-omics project ( https://github.com/BiomedSciAI/biomed-multi-omic ), offers a reproducible foundation for systematic benchmarking and community-driven exploration of optimal TFM training strategies, enabling the development of more effective tools to leverage the latest advances in AI for understanding cell biology.

Occlusion is a major challenge for LiDAR-based object detection methods. This challenge becomes safety-critical in urban traffic where the ego vehicle must have reliable object detection to avoid collision while its field of view is severely reduced due to the obstruction posed by a large number of road users. Collaborative perception via Vehicle-to-Everything (V2X) communication, which leverages the diverse perspective thanks to the presence at multiple locations of connected agents to form a complete scene representation, is an appealing solution. State-of-the-art V2X methods resolve the performance-bandwidth tradeoff using a mid-collaboration approach where the Bird-Eye View images of point clouds are exchanged so that the bandwidth consumption is lower than communicating point clouds as in early collaboration, and the detection performance is higher than late collaboration, which fuses agents' output, thanks to a deeper interaction among connected agents. While achieving strong performance, the real-world deployment of most mid-collaboration approaches is hindered by their overly complicated architectures, involving learnable collaboration graphs and autoencoder-based compressor/ decompressor, and unrealistic assumptions about inter-agent synchronization. In this work, we devise a simple yet effective collaboration method that achieves a better bandwidth-performance tradeoff than prior state-of-the-art methods while minimizing changes made to the single-vehicle detection models and relaxing unrealistic assumptions on inter-agent synchronization. Experiments on the V2X-Sim dataset show that our collaboration method achieves 98\% of the performance of an early-collaboration method, while only consuming the equivalent bandwidth of a late-collaboration method.

In this paper, we first extend the recent Masked Auto-Encoder (MAE) model from a single modality to audio-visual multi-modalities. Subsequently, we propose the Contrastive Audio-Visual Masked Auto-Encoder (CAV-MAE) by combining contrastive learning and masked data modeling, two major self-supervised learning frameworks, to learn a joint and coordinated audio-visual representation. Our experiments show that the contrastive audio-visual correspondence learning objective not only enables the model to perform audio-visual retrieval tasks, but also helps the model learn a better joint representation. As a result, our fully self-supervised pretrained CAV-MAE achieves a new SOTA accuracy of 65.9% on VGGSound, and is comparable with the previous best supervised pretrained model on AudioSet in the audio-visual event classification task. Code and pretrained models are at https://github.com/yuangongnd/cav-mae.

The integration of multi-omics single-cell data remains challenging due to high-dimensionality and complex inter-modality relationships. To address this, we introduce MoRE-GNN (Multi-omics Relational Edge Graph Neural Network), a heterogeneous graph autoencoder that combines graph convolution and attention mechanisms to dynamically construct relational graphs directly from data. Evaluations on six publicly available datasets demonstrate that MoRE-GNN captures biologically meaningful relationships and outperforms existing methods, particularly in settings with strong inter-modality correlations. Furthermore, the learned representations allow for accurate downstream cross-modal predictions. While performance may vary with dataset complexity, MoRE-GNN offers an adaptive, scalable and interpretable framework for advancing multi-omics integration.

Image clustering is one of the most important computer vision applications, which has been extensively studied in literature. However, current clustering methods mostly suffer from lack of efficiency and scalability when dealing with large-scale and high-dimensional data. In this paper, we propose a new clustering model, called DEeP Embedded RegularIzed ClusTering (DEPICT), which efficiently maps data into a discriminative embedding subspace and precisely predicts cluster assignments. DEPICT generally consists of a multinomial logistic regression function stacked on top of a multi-layer convolutional autoencoder. We define a clustering objective function using relative entropy (KL divergence) minimization, regularized by a prior for the frequency of cluster assignments. An alternating strategy is then derived to optimize the objective by updating parameters and estimating cluster assignments. Furthermore, we employ the reconstruction loss functions in our autoencoder, as a data-dependent regularization term, to prevent the deep embedding function from overfitting. In order to benefit from end-to-end optimization and eliminate the necessity for layer-wise pretraining, we introduce a joint learning framework to minimize the unified clustering and reconstruction loss functions together and train all network layers simultaneously. Experimental results indicate the superiority and faster running time of DEPICT in real-world clustering tasks, where no labeled data is available for hyper-parameter tuning.

While 3D content generation has advanced significantly, existing methods still face challenges with input formats, latent space design, and output representations. This paper introduces a novel 3D generation framework that addresses these challenges, offering scalable, high-quality 3D generation with an interactive Point Cloud-structured Latent space. Our framework employs a Variational Autoencoder (VAE) with multi-view posed RGB-D(epth)-N(ormal) renderings as input, using a unique latent space design that preserves 3D shape information, and incorporates a cascaded latent diffusion model for improved shape-texture disentanglement. The proposed method, GaussianAnything, supports multi-modal conditional 3D generation, allowing for point cloud, caption, and single/multi-view image inputs. Notably, the newly proposed latent space naturally enables geometry-texture disentanglement, thus allowing 3D-aware editing. Experimental results demonstrate the effectiveness of our approach on multiple datasets, outperforming existing methods in both text- and image-conditioned 3D generation.

Generating high resolution 3D shapes using volumetric representations such as Signed Distance Functions presents substantial computational and memory challenges. We introduce Direct3D S2, a scalable 3D generation framework based on sparse volumes that achieves superior output quality with dramatically reduced training costs. Our key innovation is the Spatial Sparse Attention mechanism, which greatly enhances the efficiency of Diffusion Transformer computations on sparse volumetric data. SSA allows the model to effectively process large token sets within sparse volumes, significantly reducing computational overhead and achieving a 3.9x speedup in the forward pass and a 9.6x speedup in the backward pass. Our framework also includes a variational autoencoder that maintains a consistent sparse volumetric format across input, latent, and output stages. Compared to previous methods with heterogeneous representations in 3D VAE, this unified design significantly improves training efficiency and stability. Our model is trained on public available datasets, and experiments demonstrate that Direct3D S2 not only surpasses state-of-the-art methods in generation quality and efficiency, but also enables training at 1024 resolution using only 8 GPUs, a task typically requiring at least 32 GPUs for volumetric representations at 256 resolution, thus making gigascale 3D generation both practical and accessible. Project page: https://nju3dv.github.io/projects/Direct3D-S2/.

Modeling the time-dependent evolution of electron density is essential for understanding quantum mechanical behaviors of condensed matter and enabling predictive simulations in spectroscopy, photochemistry, and ultrafast science. Yet, while machine learning methods have advanced static density prediction, modeling its spatiotemporal dynamics remains largely unexplored. In this work, we introduce a generative framework that combines a 3D convolutional autoencoder with a latent diffusion model (LDM) to learn electron density trajectories from ab-initio molecular dynamics (AIMD) simulations. Our method encodes electron densities into a compact latent space and predicts their future states by sampling from the learned conditional distribution, enabling stable long-horizon rollouts without drift or collapse. To preserve statistical fidelity, we incorporate a scaled Jensen-Shannon divergence regularization that aligns generated and reference density distributions. On AIMD trajectories of liquid lithium at 800 K, our model accurately captures both the spatial correlations and the log-normal-like statistical structure of the density. The proposed framework has the potential to accelerate the simulation of quantum dynamics and overcome key challenges faced by current spatiotemporal machine learning methods as surrogates of quantum mechanical simulators.

Designing neural networks typically relies on manual trial and error or a neural architecture search (NAS) followed by weight training. The former is time-consuming and labor-intensive, while the latter often discretizes architecture search and weight optimization. In this paper, we propose a fundamentally different approach that simultaneously optimizes both the architecture and the weights of a neural network. Our framework first trains a universal multi-scale autoencoder that embeds both architectural and parametric information into a continuous latent space, where functionally similar neural networks are mapped closer together. Given a dataset, we then randomly initialize a point in the embedding space and update it via gradient descent to obtain the optimal neural network, jointly optimizing its structure and weights. The optimization process incorporates sparsity and compactness penalties to promote efficient models. Experiments on synthetic regression tasks demonstrate that our method effectively discovers sparse and compact neural networks with strong performance.

This paper proposes a hierarchical generative model with a multi-grained latent variable to synthesize expressive speech. In recent years, fine-grained latent variables are introduced into the text-to-speech synthesis that enable the fine control of the prosody and speaking styles of synthesized speech. However, the naturalness of speech degrades when these latent variables are obtained by sampling from the standard Gaussian prior. To solve this problem, we propose a novel framework for modeling the fine-grained latent variables, considering the dependence on an input text, a hierarchical linguistic structure, and a temporal structure of latent variables. This framework consists of a multi-grained variational autoencoder, a conditional prior, and a multi-level auto-regressive latent converter to obtain the different time-resolution latent variables and sample the finer-level latent variables from the coarser-level ones by taking into account the input text. Experimental results indicate an appropriate method of sampling fine-grained latent variables without the reference signal at the synthesis stage. Our proposed framework also provides the controllability of speaking style in an entire utterance.

Latent heat thermal energy storage (LHTES) systems are compelling candidates for energy storage, primarily owing to their high storage density. Improving their performance is crucial for developing the next-generation efficient and cost effective devices. Topology optimization (TO) has emerged as a powerful computational tool to design LHTES systems by optimally distributing a high-conductivity material (HCM) and a phase change material (PCM). However, conventional TO typically limits to optimizing the geometry for a fixed, pre-selected materials. This approach does not leverage the large and expanding databases of novel materials. Consequently, the co-design of material and geometry for LHTES remains a challenge and unexplored. To address this limitation, we present an automated design framework for the concurrent optimization of material choice and topology. A key challenge is the discrete nature of material selection, which is incompatible with the gradient-based methods used for TO. We overcome this by using a data-driven variational autoencoder (VAE) to project discrete material databases for both the HCM and PCM onto continuous and differentiable latent spaces. These continuous material representations are integrated into an end-to-end differentiable, transient nonlinear finite-element solver that accounts for phase change. We demonstrate this framework on a problem aimed at maximizing the discharged energy within a specified time, subject to cost constraints. The effectiveness of the proposed method is validated through several illustrative examples.

We propose E-MD3C (Efficient Masked Diffusion Transformer with Disentangled Conditions and Compact Collector), a highly efficient framework for zero-shot object image customization. Unlike prior works reliant on resource-intensive Unet architectures, our approach employs lightweight masked diffusion transformers operating on latent patches, offering significantly improved computational efficiency. The framework integrates three core components: (1) an efficient masked diffusion transformer for processing autoencoder latents, (2) a disentangled condition design that ensures compactness while preserving background alignment and fine details, and (3) a learnable Conditions Collector that consolidates multiple inputs into a compact representation for efficient denoising and learning. E-MD3C outperforms the existing approach on the VITON-HD dataset across metrics such as PSNR, FID, SSIM, and LPIPS, demonstrating clear advantages in parameters, memory efficiency, and inference speed. With only 1{4} of the parameters, our Transformer-based 468M model delivers 2.5times faster inference and uses 2{3} of the GPU memory compared to an 1720M Unet-based latent diffusion model.

Generating time series data using Generative Adversarial Networks (GANs) presents several prevalent challenges, such as slow convergence, information loss in embedding spaces, instability, and performance variability depending on the series length. To tackle these obstacles, we introduce a robust framework aimed at addressing and mitigating these issues effectively. This advanced framework integrates the benefits of an Autoencoder-generated embedding space with the adversarial training dynamics of GANs. This framework benefits from a time series-based loss function and oversight from a supervisory network, both of which capture the stepwise conditional distributions of the data effectively. The generator functions within the latent space, while the discriminator offers essential feedback based on the feature space. Moreover, we introduce an early generation algorithm and an improved neural network architecture to enhance stability and ensure effective generalization across both short and long time series. Through joint training, our framework consistently outperforms existing benchmarks, generating high-quality time series data across a range of real and synthetic datasets with diverse characteristics.

Unsupervised sentence embeddings task aims to convert sentences to semantic vector representations. Most previous works directly use the sentence representations derived from pretrained language models. However, due to the token bias in pretrained language models, the models can not capture the fine-grained semantics in sentences, which leads to poor predictions. To address this issue, we propose a novel Self-Adaptive Reconstruction Contrastive Sentence Embeddings (SARCSE) framework, which reconstructs all tokens in sentences with an AutoEncoder to help the model to preserve more fine-grained semantics during tokens aggregating. In addition, we proposed a self-adaptive reconstruction loss to alleviate the token bias towards frequency. Experimental results show that SARCSE gains significant improvements compared with the strong baseline SimCSE on the 7 STS tasks.

Although recent advancements in diffusion models have significantly enriched the quality of generated images, challenges remain in synthesizing pixel-based human-drawn sketches, a representative example of abstract expression. To combat these challenges, we propose StableSketcher, a novel framework that empowers diffusion models to generate hand-drawn sketches with high prompt fidelity. Within this framework, we fine-tune the variational autoencoder to optimize latent decoding, enabling it to better capture the characteristics of sketches. In parallel, we integrate a new reward function for reinforcement learning based on visual question answering, which improves text-image alignment and semantic consistency. Extensive experiments demonstrate that StableSketcher generates sketches with improved stylistic fidelity, achieving better alignment with prompts compared to the Stable Diffusion baseline. Additionally, we introduce SketchDUO, to the best of our knowledge, the first dataset comprising instance-level sketches paired with captions and question-answer pairs, thereby addressing the limitations of existing datasets that rely on image-label pairs. Our code and dataset will be made publicly available upon acceptance.

Graph anomaly detection (GAD) has become an increasingly important task across various domains. With the rapid development of graph neural networks (GNNs), GAD methods have achieved significant performance improvements. However, fairness considerations in GAD remain largely underexplored. Indeed, GNN-based GAD models can inherit and amplify biases present in training data, potentially leading to unfair outcomes. While existing efforts have focused on developing fair GNNs, most approaches target node classification tasks, where models often rely on simple layer architectures rather than autoencoder-based structures, which are the most widely used architecturs for anomaly detection. To address fairness in autoencoder-based GAD models, we propose DisEntangled Counterfactual Adversarial Fair (DECAF)-GAD, a framework that alleviates bias while preserving GAD performance. Specifically, we introduce a structural causal model (SCM) to disentangle sensitive attributes from learned representations. Based on this causal framework, we formulate a specialized autoencoder architecture along with a fairness-guided loss function. Through extensive experiments on both synthetic and real-world datasets, we demonstrate that DECAF-GAD not only achieves competitive anomaly detection performance but also significantly enhances fairness metrics compared to baseline GAD methods. Our code is available at https://github.com/Tlhey/decaf_code.

Neural audio autoencoders create compact latent representations that preserve perceptually important information, serving as the foundation for both modern audio compression systems and generation approaches like next-token prediction and latent diffusion. Despite their prevalence, most audio processing operations, such as spatial and spectral up-sampling, still inefficiently operate on raw waveforms or spectral representations rather than directly on these compressed representations. We propose a framework that performs audio processing operations entirely within an autoencoder's latent space, eliminating the need to decode to raw audio formats. Our approach dramatically simplifies training by operating solely in the latent domain, with a latent L1 reconstruction term, augmented by a single latent adversarial discriminator. This contrasts sharply with raw-audio methods that typically require complex combinations of multi-scale losses and discriminators. Through experiments in bandwidth extension and mono-to-stereo up-mixing, we demonstrate computational efficiency gains of up to 100x while maintaining quality comparable to post-processing on raw audio. This work establishes a more efficient paradigm for audio processing pipelines that already incorporate autoencoders, enabling significantly faster and more resource-efficient workflows across various audio tasks.

A prominent approach to visual Reinforcement Learning (RL) is to learn an internal state representation using self-supervised methods, which has the potential benefit of improved sample-efficiency and generalization through additional learning signal and inductive biases. However, while the real world is inherently 3D, prior efforts have largely been focused on leveraging 2D computer vision techniques as auxiliary self-supervision. In this work, we present a unified framework for self-supervised learning of 3D representations for motor control. Our proposed framework consists of two phases: a pretraining phase where a deep voxel-based 3D autoencoder is pretrained on a large object-centric dataset, and a finetuning phase where the representation is jointly finetuned together with RL on in-domain data. We empirically show that our method enjoys improved sample efficiency in simulated manipulation tasks compared to 2D representation learning methods. Additionally, our learned policies transfer zero-shot to a real robot setup with only approximate geometric correspondence, and successfully solve motor control tasks that involve grasping and lifting from a single, uncalibrated RGB camera. Code and videos are available at https://yanjieze.com/3d4rl/ .

This paper presents a novel approach to neural instrument sound synthesis using a two-stage semi-supervised learning framework capable of generating pitch-accurate, high-quality music samples from an expressive timbre latent space. Existing approaches that achieve sufficient quality for music production often rely on high-dimensional latent representations that are difficult to navigate and provide unintuitive user experiences. We address this limitation through a two-stage training paradigm: first, we train a pitch-timbre disentangled 2D representation of audio samples using a Variational Autoencoder; second, we use this representation as conditioning input for a Transformer-based generative model. The learned 2D latent space serves as an intuitive interface for navigating and exploring the sound landscape. We demonstrate that the proposed method effectively learns a disentangled timbre space, enabling expressive and controllable audio generation with reliable pitch conditioning. Experimental results show the model's ability to capture subtle variations in timbre while maintaining a high degree of pitch accuracy. The usability of our method is demonstrated in an interactive web application, highlighting its potential as a step towards future music production environments that are both intuitive and creatively empowering: https://pgesam.faresschulz.com

This paper presents a novel framework that enables real-world humanoid robots to maintain stability while performing human-like motion. Current methods train a policy which allows humanoid robots to follow human body using the massive retargeted human data via reinforcement learning. However, due to the heterogeneity between human and humanoid robot motion, directly using retargeted human motion reduces training efficiency and stability. To this end, we introduce SMAP, a novel whole-body tracking framework that bridges the gap between human and humanoid action spaces, enabling accurate motion mimicry by humanoid robots. The core idea is to use a vector-quantized periodic autoencoder to capture generic atomic behaviors and adapt human motion into physically plausible humanoid motion. This adaptation accelerates training convergence and improves stability when handling novel or challenging motions. We then employ a privileged teacher to distill precise mimicry skills into the student policy with a proposed decoupled reward. We conduct experiments in simulation and real world to demonstrate the superiority stability and performance of SMAP over SOTA methods, offering practical guidelines for advancing whole-body control in humanoid robots.

Chest X-rays (CXRs) are commonly utilized as a low-dose modality for lung screening. Nonetheless, the efficacy of CXRs is somewhat impeded, given that approximately 75% of the lung area overlaps with bone, which in turn hampers the detection and diagnosis of diseases. As a remedial measure, bone suppression techniques have been introduced. The current dual-energy subtraction imaging technique in the clinic requires costly equipment and subjects being exposed to high radiation. To circumvent these issues, deep learning-based image generation algorithms have been proposed. However, existing methods fall short in terms of producing high-quality images and capturing texture details, particularly with pulmonary vessels. To address these issues, this paper proposes a new bone suppression framework, termed BS-Diff, that comprises a conditional diffusion model equipped with a U-Net architecture and a simple enhancement module to incorporate an autoencoder. Our proposed network cannot only generate soft tissue images with a high bone suppression rate but also possesses the capability to capture fine image details. Additionally, we compiled the largest dataset since 2010, including data from 120 patients with high-definition, high-resolution paired CXRs and soft tissue images collected by our affiliated hospital. Extensive experiments, comparative analyses, ablation studies, and clinical evaluations indicate that the proposed BS-Diff outperforms several bone-suppression models across multiple metrics. Our code can be accessed at https://github.com/Benny0323/BS-Diff.

Recent embedding-based methods have achieved great successes on exploiting entity alignment from knowledge graph (KG) embeddings of multiple modals. In this paper, we study embedding-based entity alignment (EEA) from a perspective of generative models. We show that EEA is a special problem where the main objective is analogous to that in a typical generative model, based on which we theoretically prove the effectiveness of the recently developed generative adversarial network (GAN)-based EEA methods. We then reveal that their incomplete objective limits the capacity on both entity alignment and entity synthesis (i.e., generating new entities). We mitigate this problem by introducing a generative EEA (abbr., GEEA) framework with the proposed mutual variational autoencoder (M-VAE) as the generative model. M-VAE can convert an entity from one KG to another and generate new entities from random noise vectors. We demonstrate the power of GEEA with theoretical analysis and empirical experiments on both entity alignment and entity synthesis tasks.

With the rising industrial attention to 3D virtual modeling technology, generating novel 3D content based on specified conditions (e.g. text) has become a hot issue. In this paper, we propose a new generative 3D modeling framework called Diffusion-SDF for the challenging task of text-to-shape synthesis. Previous approaches lack flexibility in both 3D data representation and shape generation, thereby failing to generate highly diversified 3D shapes conforming to the given text descriptions. To address this, we propose a SDF autoencoder together with the Voxelized Diffusion model to learn and generate representations for voxelized signed distance fields (SDFs) of 3D shapes. Specifically, we design a novel UinU-Net architecture that implants a local-focused inner network inside the standard U-Net architecture, which enables better reconstruction of patch-independent SDF representations. We extend our approach to further text-to-shape tasks including text-conditioned shape completion and manipulation. Experimental results show that Diffusion-SDF generates both higher quality and more diversified 3D shapes that conform well to given text descriptions when compared to previous approaches. Code is available at: https://github.com/ttlmh/Diffusion-SDF

Recently, interactive digital human video generation has attracted widespread attention and achieved remarkable progress. However, building such a practical system that can interact with diverse input signals in real time remains challenging to existing methods, which often struggle with high latency, heavy computational cost, and limited controllability. In this work, we introduce an autoregressive video generation framework that enables interactive multimodal control and low-latency extrapolation in a streaming manner. With minimal modifications to a standard large language model (LLM), our framework accepts multimodal condition encodings including audio, pose, and text, and outputs spatially and semantically coherent representations to guide the denoising process of a diffusion head. To support this, we construct a large-scale dialogue dataset of approximately 20,000 hours from multiple sources, providing rich conversational scenarios for training. We further introduce a deep compression autoencoder with up to 64times reduction ratio, which effectively alleviates the long-horizon inference burden of the autoregressive model. Extensive experiments on duplex conversation, multilingual human synthesis, and interactive world model highlight the advantages of our approach in low latency, high efficiency, and fine-grained multimodal controllability.

Generating full-length, high-quality songs is challenging, as it requires maintaining long-term coherence both across text and music modalities and within the music modality itself. Existing non-autoregressive (NAR) frameworks, while capable of producing high-quality songs, often struggle with the alignment between lyrics and vocal. Concurrently, catering to diverse musical preferences necessitates reinforcement learning from human feedback (RLHF). However, existing methods often rely on merging multiple models during multi-preference optimization, which results in significant performance degradation. To address these challenges, we introduce DiffRhythm 2, an end-to-end framework designed for high-fidelity, controllable song generation. To tackle the lyric alignment problem, DiffRhythm 2 employs a semi-autoregressive architecture based on block flow matching. This design enables faithful alignment of lyrics to singing vocals without relying on external labels and constraints, all while preserving the high generation quality and efficiency of NAR models. To make this framework computationally tractable for long sequences, we implement a music variational autoencoder (VAE) that achieves a low frame rate of 5 Hz while still enabling high-fidelity audio reconstruction. In addition, to overcome the limitations of multi-preference optimization in RLHF, we propose cross-pair preference optimization. This method effectively mitigates the performance drop typically associated with model merging, allowing for more robust optimization across diverse human preferences. We further enhance musicality and structural coherence by introducing stochastic block representation alignment loss.

Recent advancements in 3D diffusion-based semantic scene generation have gained attention. However, existing methods rely on unconditional generation and require multiple resampling steps when editing scenes, which significantly limits their controllability and flexibility. To this end, we propose SSEditor, a controllable Semantic Scene Editor that can generate specified target categories without multiple-step resampling. SSEditor employs a two-stage diffusion-based framework: (1) a 3D scene autoencoder is trained to obtain latent triplane features, and (2) a mask-conditional diffusion model is trained for customizable 3D semantic scene generation. In the second stage, we introduce a geometric-semantic fusion module that enhance the model's ability to learn geometric and semantic information. This ensures that objects are generated with correct positions, sizes, and categories. Extensive experiments on SemanticKITTI and CarlaSC demonstrate that SSEditor outperforms previous approaches in terms of controllability and flexibility in target generation, as well as the quality of semantic scene generation and reconstruction. More importantly, experiments on the unseen Occ-3D Waymo dataset show that SSEditor is capable of generating novel urban scenes, enabling the rapid construction of 3D scenes.

3D shape generation aims to produce innovative 3D content adhering to specific conditions and constraints. Existing methods often decompose 3D shapes into a sequence of localized components, treating each element in isolation without considering spatial consistency. As a result, these approaches exhibit limited versatility in 3D data representation and shape generation, hindering their ability to generate highly diverse 3D shapes that comply with the specified constraints. In this paper, we introduce a novel spatial-aware 3D shape generation framework that leverages 2D plane representations for enhanced 3D shape modeling. To ensure spatial coherence and reduce memory usage, we incorporate a hybrid shape representation technique that directly learns a continuous signed distance field representation of the 3D shape using orthogonal 2D planes. Additionally, we meticulously enforce spatial correspondences across distinct planes using a transformer-based autoencoder structure, promoting the preservation of spatial relationships in the generated 3D shapes. This yields an algorithm that consistently outperforms state-of-the-art 3D shape generation methods on various tasks, including unconditional shape generation, multi-modal shape completion, single-view reconstruction, and text-to-shape synthesis.

Examining Drug-Drug Interactions (DDIs) is a pivotal element in the process of drug development. DDIs occur when one drug's properties are affected by the inclusion of other drugs. Detecting favorable DDIs has the potential to pave the way for creating and advancing innovative medications applicable in practical settings. However, existing DDI prediction models continue to face challenges related to generalization in extreme cases, robust feature extraction, and real-life application possibilities. We aim to address these challenges by leveraging the effectiveness of context-aware deep graph learning by introducing a novel framework named CADGL. Based on a customized variational graph autoencoder (VGAE), we capture critical structural and physio-chemical information using two context preprocessors for feature extraction from two different perspectives: local neighborhood and molecular context, in a heterogeneous graphical structure. Our customized VGAE consists of a graph encoder, a latent information encoder, and an MLP decoder. CADGL surpasses other state-of-the-art DDI prediction models, excelling in predicting clinically valuable novel DDIs, supported by rigorous case studies.

Next token prediction has been the standard training objective used in large language model pretraining. Representations are learned as a result of optimizing for token-level perplexity. We propose Continuous Concept Mixing (CoCoMix), a novel pretraining framework that combines discrete next token prediction with continuous concepts. Specifically, CoCoMix predicts continuous concepts learned from a pretrained sparse autoencoder and mixes them into the model's hidden state by interleaving with token hidden representations. Through experiments on multiple benchmarks, including language modeling and downstream reasoning tasks, we show that CoCoMix is more sample efficient and consistently outperforms standard next token prediction, knowledge distillation and inserting pause tokens. We find that combining both concept learning and interleaving in an end-to-end framework is critical to performance gains. Furthermore, CoCoMix enhances interpretability and steerability by allowing direct inspection and modification of the predicted concept, offering a transparent way to guide the model's internal reasoning process.

This study presents Latent Diffusion Autoencoder (LDAE), a novel encoder-decoder diffusion-based framework for efficient and meaningful unsupervised learning in medical imaging, focusing on Alzheimer disease (AD) using brain MR from the ADNI database as a case study. Unlike conventional diffusion autoencoders operating in image space, LDAE applies the diffusion process in a compressed latent representation, improving computational efficiency and making 3D medical imaging representation learning tractable. To validate the proposed approach, we explore two key hypotheses: (i) LDAE effectively captures meaningful semantic representations on 3D brain MR associated with AD and ageing, and (ii) LDAE achieves high-quality image generation and reconstruction while being computationally efficient. Experimental results support both hypotheses: (i) linear-probe evaluations demonstrate promising diagnostic performance for AD (ROC-AUC: 90%, ACC: 84%) and age prediction (MAE: 4.1 years, RMSE: 5.2 years); (ii) the learned semantic representations enable attribute manipulation, yielding anatomically plausible modifications; (iii) semantic interpolation experiments show strong reconstruction of missing scans, with SSIM of 0.969 (MSE: 0.0019) for a 6-month gap. Even for longer gaps (24 months), the model maintains robust performance (SSIM > 0.93, MSE < 0.004), indicating an ability to capture temporal progression trends; (iv) compared to conventional diffusion autoencoders, LDAE significantly increases inference throughput (20x faster) while also enhancing reconstruction quality. These findings position LDAE as a promising framework for scalable medical imaging applications, with the potential to serve as a foundation model for medical image analysis. Code available at https://github.com/GabrieleLozupone/LDAE

Styled Handwritten Text Generation (HTG) has recently received attention from the computer vision and document analysis communities, which have developed several solutions, either GAN- or diffusion-based, that achieved promising results. Nonetheless, these strategies fail to generalize to novel styles and have technical constraints, particularly in terms of maximum output length and training efficiency. To overcome these limitations, in this work, we propose a novel framework for text image generation, dubbed Emuru. Our approach leverages a powerful text image representation model (a variational autoencoder) combined with an autoregressive Transformer. Our approach enables the generation of styled text images conditioned on textual content and style examples, such as specific fonts or handwriting styles. We train our model solely on a diverse, synthetic dataset of English text rendered in over 100,000 typewritten and calligraphy fonts, which gives it the capability to reproduce unseen styles (both fonts and users' handwriting) in zero-shot. To the best of our knowledge, Emuru is the first autoregressive model for HTG, and the first designed specifically for generalization to novel styles. Moreover, our model generates images without background artifacts, which are easier to use for downstream applications. Extensive evaluation on both typewritten and handwritten, any-length text image generation scenarios demonstrates the effectiveness of our approach.

Generating videos from text has proven to be a significant challenge for existing generative models. We tackle this problem by training a conditional generative model to extract both static and dynamic information from text. This is manifested in a hybrid framework, employing a Variational Autoencoder (VAE) and a Generative Adversarial Network (GAN). The static features, called "gist," are used to sketch text-conditioned background color and object layout structure. Dynamic features are considered by transforming input text into an image filter. To obtain a large amount of data for training the deep-learning model, we develop a method to automatically create a matched text-video corpus from publicly available online videos. Experimental results show that the proposed framework generates plausible and diverse videos, while accurately reflecting the input text information. It significantly outperforms baseline models that directly adapt text-to-image generation procedures to produce videos. Performance is evaluated both visually and by adapting the inception score used to evaluate image generation in GANs.

Generating high-fidelity, seamless textures directly on 3D surfaces, what we term 3D-native texturing, remains a fundamental open challenge, with the potential to overcome long-standing limitations of UV-based and multi-view projection methods. However, existing native approaches are constrained by the absence of a powerful and versatile latent representation, which severely limits the fidelity and generality of their generated textures. We identify this representation gap as the principal barrier to further progress. We introduce LaFiTe, a framework that addresses this challenge by learning to generate textures as a 3D generative sparse latent color field. At its core, LaFiTe employs a variational autoencoder (VAE) to encode complex surface appearance into a sparse, structured latent space, which is subsequently decoded into a continuous color field. This representation achieves unprecedented fidelity, exceeding state-of-the-art methods by >10 dB PSNR in reconstruction, by effectively disentangling texture appearance from mesh topology and UV parameterization. Building upon this strong representation, a conditional rectified-flow model synthesizes high-quality, coherent textures across diverse styles and geometries. Extensive experiments demonstrate that LaFiTe not only sets a new benchmark for 3D-native texturing but also enables flexible downstream applications such as material synthesis and texture super-resolution, paving the way for the next generation of 3D content creation workflows.

In Decentralized Multi-Agent Reinforcement Learning (MARL), the development of Emergent Communication has long been constrained by the ``Joint Exploration Dilemma'', leading agents to fall into a ``Communication Vacuum Equilibrium'' . Traditional methods address this by introducing inductive biases to facilitate communication emergence . This study fundamentally questions whether such artificial inductive biases are, in fact, over-engineering. Through experiments with the ``AI Mother Tongue'' (AIM) framework, based on a Vector Quantized Variational Autoencoder (VQ-VAE), we demonstrate that when agents possess an endogenous symbol system, their neural representations naturally exhibit spontaneous semantic compression and Nash equilibrium-driven semantic convergence, achieving effective symbolic communication without external inductive biases. This aligns with recent neuroscience findings suggesting that the human brain does not directly use human language for internal thought , and resonates with research on ``soft thinking'' capabilities in Large Language Models (LLMs) . Compared to traditional explicit communication methods, AIM demonstrates stronger generality and efficiency. The interpretable analysis toolkit developed in this study confirms that symbol usage exhibits a significant power-law distribution, leading to three major theoretical insights: the ``Neural Communication Hypothesis'', the ``Tool-First Principle'', and the ``Semantic Interpretability Paradigm''. Future research will explore the integration of Hierarchical Quantized Variational Autoencoders (HQ-VAE) to enhance AIM's complex expressive capabilities and investigate the potential for ``Reinforcement Learning (RL) Low-Level Pre-training''. This discovery offers new avenues for bridging symbolism and connectionism.

Accurate ocean modeling and coastal hazard prediction depend on high-resolution bathymetric data; yet, current worldwide datasets are too coarse for exact numerical simulations. While recent deep learning advances have improved earth observation data resolution, existing methods struggle with the unique challenges of producing detailed ocean floor maps, especially in maintaining physical structure consistency and quantifying uncertainties. This work presents a novel uncertainty-aware mechanism using spatial blocks to efficiently capture local bathymetric complexity based on block-based conformal prediction. Using the Vector Quantized Variational Autoencoder (VQ-VAE) architecture, the integration of this uncertainty quantification framework yields spatially adaptive confidence estimates while preserving topographical features via discrete latent representations. With smaller uncertainty widths in well-characterized areas and appropriately larger bounds in areas of complex seafloor structures, the block-based design adapts uncertainty estimates to local bathymetric complexity. Compared to conventional techniques, experimental results over several ocean regions show notable increases in both reconstruction quality and uncertainty estimation reliability. This framework increases the reliability of bathymetric reconstructions by preserving structural integrity while offering spatially adaptive uncertainty estimates, so opening the path for more solid climate modeling and coastal hazard assessment.

In this work, we develop a joint denoising and feedback strategy for channel state information in frequency division duplex systems. In such systems, the biggest challenge is the overhead incurred when the mobile terminal has to send the downlink channel state information or corresponding partial information to the base station, where the complete estimates can subsequently be restored. To this end, we propose a novel learning-based framework for denoising and compression of channel estimates. Unlike existing studies, we extend a recently proposed approach and show that based solely on noisy uplink data available at the base station, it is possible to learn an autoencoder neural network that generalizes to downlink data. Subsequently, half of the autoencoder can be offloaded to the mobile terminals to generate channel feedback there as efficiently as possible, without any training effort at the terminals or corresponding transfer of training data. Numerical simulations demonstrate the excellent performance of the proposed method.

Latent diffusion models (LDMs) dominate high-quality image generation, yet integrating representation learning with generative modeling remains a challenge. We introduce a novel generative image modeling framework that seamlessly bridges this gap by leveraging a diffusion model to jointly model low-level image latents (from a variational autoencoder) and high-level semantic features (from a pretrained self-supervised encoder like DINO). Our latent-semantic diffusion approach learns to generate coherent image-feature pairs from pure noise, significantly enhancing both generative quality and training efficiency, all while requiring only minimal modifications to standard Diffusion Transformer architectures. By eliminating the need for complex distillation objectives, our unified design simplifies training and unlocks a powerful new inference strategy: Representation Guidance, which leverages learned semantics to steer and refine image generation. Evaluated in both conditional and unconditional settings, our method delivers substantial improvements in image quality and training convergence speed, establishing a new direction for representation-aware generative modeling.

This paper introduces DanceFusion, a novel framework for reconstructing and generating dance movements synchronized to music, utilizing a Spatio-Temporal Skeleton Diffusion Transformer. The framework adeptly handles incomplete and noisy skeletal data common in short-form dance videos on social media platforms like TikTok. DanceFusion incorporates a hierarchical Transformer-based Variational Autoencoder (VAE) integrated with a diffusion model, significantly enhancing motion realism and accuracy. Our approach introduces sophisticated masking techniques and a unique iterative diffusion process that refines the motion sequences, ensuring high fidelity in both motion generation and synchronization with accompanying audio cues. Comprehensive evaluations demonstrate that DanceFusion surpasses existing methods, providing state-of-the-art performance in generating dynamic, realistic, and stylistically diverse dance motions. Potential applications of this framework extend to content creation, virtual reality, and interactive entertainment, promising substantial advancements in automated dance generation. Visit our project page at https://th-mlab.github.io/DanceFusion/.

This work addresses the problem of generating 3D holistic body motions from human speech. Given a speech recording, we synthesize sequences of 3D body poses, hand gestures, and facial expressions that are realistic and diverse. To achieve this, we first build a high-quality dataset of 3D holistic body meshes with synchronous speech. We then define a novel speech-to-motion generation framework in which the face, body, and hands are modeled separately. The separated modeling stems from the fact that face articulation strongly correlates with human speech, while body poses and hand gestures are less correlated. Specifically, we employ an autoencoder for face motions, and a compositional vector-quantized variational autoencoder (VQ-VAE) for the body and hand motions. The compositional VQ-VAE is key to generating diverse results. Additionally, we propose a cross-conditional autoregressive model that generates body poses and hand gestures, leading to coherent and realistic motions. Extensive experiments and user studies demonstrate that our proposed approach achieves state-of-the-art performance both qualitatively and quantitatively. Our novel dataset and code will be released for research purposes at https://talkshow.is.tue.mpg.de.

We introduce Sana, a text-to-image framework that can efficiently generate images up to 4096times4096 resolution. Sana can synthesize high-resolution, high-quality images with strong text-image alignment at a remarkably fast speed, deployable on laptop GPU. Core designs include: (1) Deep compression autoencoder: unlike traditional AEs, which compress images only 8times, we trained an AE that can compress images 32times, effectively reducing the number of latent tokens. (2) Linear DiT: we replace all vanilla attention in DiT with linear attention, which is more efficient at high resolutions without sacrificing quality. (3) Decoder-only text encoder: we replaced T5 with modern decoder-only small LLM as the text encoder and designed complex human instruction with in-context learning to enhance the image-text alignment. (4) Efficient training and sampling: we propose Flow-DPM-Solver to reduce sampling steps, with efficient caption labeling and selection to accelerate convergence. As a result, Sana-0.6B is very competitive with modern giant diffusion model (e.g. Flux-12B), being 20 times smaller and 100+ times faster in measured throughput. Moreover, Sana-0.6B can be deployed on a 16GB laptop GPU, taking less than 1 second to generate a 1024times1024 resolution image. Sana enables content creation at low cost. Code and model will be publicly released.

RGBA video generation, which includes an alpha channel to represent transparency, is gaining increasing attention across a wide range of applications. However, existing methods often neglect visual quality, limiting their practical usability. In this paper, we propose Wan-Alpha, a new framework that generates transparent videos by learning both RGB and alpha channels jointly. We design an effective variational autoencoder (VAE) that encodes the alpha channel into the RGB latent space. Then, to support the training of our diffusion transformer, we construct a high-quality and diverse RGBA video dataset. Compared with state-of-the-art methods, our model demonstrates superior performance in visual quality, motion realism, and transparency rendering. Notably, our model can generate a wide variety of semi-transparent objects, glowing effects, and fine-grained details such as hair strands. The released model is available on our website: https://donghaotian123.github.io/Wan-Alpha/{https://donghaotian123.github.io/Wan-Alpha/}.

Health Indicators (HIs) are essential for predicting system failures in predictive maintenance. While methods like RaPP (Reconstruction along Projected Pathways) improve traditional HI approaches by leveraging autoencoder latent spaces, their performance can be hindered by both aleatoric and epistemic uncertainties. In this paper, we propose a novel framework that integrates uncertainty quantification into autoencoder-based latent spaces, enhancing RaPP-generated HIs. We demonstrate that separating aleatoric uncertainty from epistemic uncertainty and cross combining HI information is the driver of accuracy improvements in Remaining Useful Life (RUL) prediction. Our method employs both standard and variational autoencoders to construct these HIs, which are then used to train a machine learning model for RUL prediction. Benchmarked on the NASA C-MAPSS turbofan dataset, our approach outperforms traditional HI-based methods and end-to-end RUL prediction models and is competitive with RUL estimation methods. These results underscore the importance of uncertainty quantification in health assessment and showcase its significant impact on predictive performance when incorporated into the HI construction process.

Directly producing planning results from raw sensors has been a long-desired solution for autonomous driving and has attracted increasing attention recently. Most existing end-to-end autonomous driving methods factorize this problem into perception, motion prediction, and planning. However, we argue that the conventional progressive pipeline still cannot comprehensively model the entire traffic evolution process, e.g., the future interaction between the ego car and other traffic participants and the structural trajectory prior. In this paper, we explore a new paradigm for end-to-end autonomous driving, where the key is to predict how the ego car and the surroundings evolve given past scenes. We propose GenAD, a generative framework that casts autonomous driving into a generative modeling problem. We propose an instance-centric scene tokenizer that first transforms the surrounding scenes into map-aware instance tokens. We then employ a variational autoencoder to learn the future trajectory distribution in a structural latent space for trajectory prior modeling. We further adopt a temporal model to capture the agent and ego movements in the latent space to generate more effective future trajectories. GenAD finally simultaneously performs motion prediction and planning by sampling distributions in the learned structural latent space conditioned on the instance tokens and using the learned temporal model to generate futures. Extensive experiments on the widely used nuScenes benchmark show that the proposed GenAD achieves state-of-the-art performance on vision-centric end-to-end autonomous driving with high efficiency. Code: https://github.com/wzzheng/GenAD.

Role-playing has emerged as an effective technique for enhancing the reasoning capabilities of large language models (LLMs). However, existing methods primarily rely on prompt engineering, which often lacks stability and interpretability. In this paper, we introduce Sparse Autoencoder Role-Playing Steering (SRPS), a novel framework that identifies and manipulates internal model features associated with role-playing behavior. Our approach extracts latent representations from role-play prompts, selects the most relevant features based on activation patterns, and constructs a steering vector that can be injected into the model's residual stream with controllable intensity. Our method enables fine-grained control over role-specific behavior and offers insights into how role information influences internal model activations. Extensive experiments across various reasoning benchmarks and model sizes demonstrate consistent performance gains. Notably, in the zero-shot chain-of-thought (CoT) setting, the accuracy of Llama3.1-8B on CSQA improves from 31.86% to 39.80%, while Gemma2-9B on SVAMP increases from 37.50% to 45.10%. These results highlight the potential of SRPS to enhance reasoning ability in LLMs, providing better interpretability and stability compared to traditional prompt-based role-playing.

Trajectory prediction has been a crucial task in building a reliable autonomous driving system by anticipating possible dangers. One key issue is to generate consistent trajectory predictions without colliding. To overcome the challenge, we propose an efficient masked autoencoder for trajectory prediction (Traj-MAE) that better represents the complicated behaviors of agents in the driving environment. Specifically, our Traj-MAE employs diverse masking strategies to pre-train the trajectory encoder and map encoder, allowing for the capture of social and temporal information among agents while leveraging the effect of environment from multiple granularities. To address the catastrophic forgetting problem that arises when pre-training the network with multiple masking strategies, we introduce a continual pre-training framework, which can help Traj-MAE learn valuable and diverse information from various strategies efficiently. Our experimental results in both multi-agent and single-agent settings demonstrate that Traj-MAE achieves competitive results with state-of-the-art methods and significantly outperforms our baseline model.

Large language models (LLM)-based speech synthesis has been widely adopted in zero-shot speech synthesis. However, they require a large-scale data and possess the same limitations as previous autoregressive speech models, including slow inference speed and lack of robustness. This paper proposes HierSpeech++, a fast and strong zero-shot speech synthesizer for text-to-speech (TTS) and voice conversion (VC). We verified that hierarchical speech synthesis frameworks could significantly improve the robustness and expressiveness of the synthetic speech. Furthermore, we significantly improve the naturalness and speaker similarity of synthetic speech even in zero-shot speech synthesis scenarios. For text-to-speech, we adopt the text-to-vec framework, which generates a self-supervised speech representation and an F0 representation based on text representations and prosody prompts. Then, HierSpeech++ generates speech from the generated vector, F0, and voice prompt. We further introduce a high-efficient speech super-resolution framework from 16 kHz to 48 kHz. The experimental results demonstrated that the hierarchical variational autoencoder could be a strong zero-shot speech synthesizer given that it outperforms LLM-based and diffusion-based models. Moreover, we achieved the first human-level quality zero-shot speech synthesis. Audio samples and source code are available at https://github.com/sh-lee-prml/HierSpeechpp.

Robust tooling and publicly available pre-trained models have helped drive recent advances in mechanistic interpretability for language models. However, similar progress in vision mechanistic interpretability has been hindered by the lack of accessible frameworks and pre-trained weights. We present Prisma (Access the codebase here: https://github.com/Prisma-Multimodal/ViT-Prisma), an open-source framework designed to accelerate vision mechanistic interpretability research, providing a unified toolkit for accessing 75+ vision and video transformers; support for sparse autoencoder (SAE), transcoder, and crosscoder training; a suite of 80+ pre-trained SAE weights; activation caching, circuit analysis tools, and visualization tools; and educational resources. Our analysis reveals surprising findings, including that effective vision SAEs can exhibit substantially lower sparsity patterns than language SAEs, and that in some instances, SAE reconstructions can decrease model loss. Prisma enables new research directions for understanding vision model internals while lowering barriers to entry in this emerging field.

Diffusion models are the standard toolkit for generative modelling of 3D atomic systems. However, for different types of atomic systems - such as molecules and materials - the generative processes are usually highly specific to the target system despite the underlying physics being the same. We introduce the All-atom Diffusion Transformer (ADiT), a unified latent diffusion framework for jointly generating both periodic materials and non-periodic molecular systems using the same model: (1) An autoencoder maps a unified, all-atom representations of molecules and materials to a shared latent embedding space; and (2) A diffusion model is trained to generate new latent embeddings that the autoencoder can decode to sample new molecules or materials. Experiments on QM9 and MP20 datasets demonstrate that jointly trained ADiT generates realistic and valid molecules as well as materials, exceeding state-of-the-art results from molecule and crystal-specific models. ADiT uses standard Transformers for both the autoencoder and diffusion model, resulting in significant speedups during training and inference compared to equivariant diffusion models. Scaling ADiT up to half a billion parameters predictably improves performance, representing a step towards broadly generalizable foundation models for generative chemistry. Open source code: https://github.com/facebookresearch/all-atom-diffusion-transformer

Rapid growth of high-dimensional datasets in fields such as single-cell RNA sequencing and spatial genomics has led to unprecedented opportunities for scientific discovery, but it also presents unique computational and statistical challenges. Traditional methods struggle with geometry-aware data generation, interpolation along meaningful trajectories, and transporting populations via feasible paths. To address these issues, we introduce Geometry-Aware Generative Autoencoder (GAGA), a novel framework that combines extensible manifold learning with generative modeling. GAGA constructs a neural network embedding space that respects the intrinsic geometries discovered by manifold learning and learns a novel warped Riemannian metric on the data space. This warped metric is derived from both the points on the data manifold and negative samples off the manifold, allowing it to characterize a meaningful geometry across the entire latent space. Using this metric, GAGA can uniformly sample points on the manifold, generate points along geodesics, and interpolate between populations across the learned manifold using geodesic-guided flows. GAGA shows competitive performance in simulated and real-world datasets, including a 30% improvement over the state-of-the-art methods in single-cell population-level trajectory inference.

In this work, we investigate a simple and must-known conditional generative framework based on Vector Quantised-Variational AutoEncoder (VQ-VAE) and Generative Pre-trained Transformer (GPT) for human motion generation from textural descriptions. We show that a simple CNN-based VQ-VAE with commonly used training recipes (EMA and Code Reset) allows us to obtain high-quality discrete representations. For GPT, we incorporate a simple corruption strategy during the training to alleviate training-testing discrepancy. Despite its simplicity, our T2M-GPT shows better performance than competitive approaches, including recent diffusion-based approaches. For example, on HumanML3D, which is currently the largest dataset, we achieve comparable performance on the consistency between text and generated motion (R-Precision), but with FID 0.116 largely outperforming MotionDiffuse of 0.630. Additionally, we conduct analyses on HumanML3D and observe that the dataset size is a limitation of our approach. Our work suggests that VQ-VAE still remains a competitive approach for human motion generation.

Generating images with embedded text is crucial for the automatic production of visual and multimodal documents, such as educational materials and advertisements. However, existing diffusion-based text-to-image models often struggle to accurately embed text within images, facing challenges in spelling accuracy, contextual relevance, and visual coherence. Evaluating the ability of such models to embed text within a generated image is complicated due to the lack of comprehensive benchmarks. In this work, we introduce TextInVision, a large-scale, text and prompt complexity driven benchmark designed to evaluate the ability of diffusion models to effectively integrate visual text into images. We crafted a diverse set of prompts and texts that consider various attributes and text characteristics. Additionally, we prepared an image dataset to test Variational Autoencoder (VAE) models across different character representations, highlighting that VAE architectures can also pose challenges in text generation within diffusion frameworks. Through extensive analysis of multiple models, we identify common errors and highlight issues such as spelling inaccuracies and contextual mismatches. By pinpointing the failure points across different prompts and texts, our research lays the foundation for future advancements in AI-generated multimodal content.

Expressive voice conversion aims to transfer both speaker identity and expressive attributes from a target speech to a given source speech. In this work, we improve over a self-supervised, non-autoregressive framework with a conditional variational autoencoder, focusing on reducing source timbre leakage and improving linguistic-acoustic disentanglement for better style transfer. To minimize style leakage, we use multilingual discrete speech units for content representation and reinforce embeddings with augmentation-based similarity loss and mix-style layer normalization. To enhance expressivity transfer, we incorporate local F0 information via cross-attention and extract style embeddings enriched with global pitch and energy features. Experiments show our model outperforms baselines in emotion and speaker similarity, demonstrating superior style adaptation and reduced source style leakage.

Recent studies have highlighted the interplay between diffusion models and representation learning. Intermediate representations from diffusion models can be leveraged for downstream visual tasks, while self-supervised vision models can enhance the convergence and generation quality of diffusion models. However, transferring pretrained weights from vision models to diffusion models is challenging due to input mismatches and the use of latent spaces. To address these challenges, we propose Unified Self-supervised Pretraining (USP), a framework that initializes diffusion models via masked latent modeling in a Variational Autoencoder (VAE) latent space. USP achieves comparable performance in understanding tasks while significantly improving the convergence speed and generation quality of diffusion models. Our code will be publicly available at https://github.com/cxxgtxy/USP.

State-space models (SSMs) offer a powerful framework for dynamical system analysis, wherein the temporal dynamics of the system are assumed to be captured through the evolution of the latent states, which govern the values of the observations. This paper provides a selective review of recent advancements in deep neural network-based approaches for SSMs, and presents a unified perspective for discrete time deep state space models and continuous time ones such as latent neural Ordinary Differential and Stochastic Differential Equations. It starts with an overview of the classical maximum likelihood based approach for learning SSMs, reviews variational autoencoder as a general learning pipeline for neural network-based approaches in the presence of latent variables, and discusses in detail representative deep learning models that fall under the SSM framework. Very recent developments, where SSMs are used as standalone architectural modules for improving efficiency in sequence modeling, are also examined. Finally, examples involving mixed frequency and irregularly-spaced time series data are presented to demonstrate the advantage of SSMs in these settings.

Building state-of-the-art Vision-Language Models (VLMs) with strong captioning capabilities typically necessitates training on billions of high-quality image-text pairs, requiring millions of GPU hours. This paper introduces the Vision-Language-Vision (VLV) auto-encoder framework, which strategically leverages key pretrained components: a vision encoder, the decoder of a Text-to-Image (T2I) diffusion model, and subsequently, a Large Language Model (LLM). Specifically, we establish an information bottleneck by regularizing the language representation space, achieved through freezing the pretrained T2I diffusion decoder. Our VLV pipeline effectively distills knowledge from the text-conditioned diffusion model using continuous embeddings, demonstrating comprehensive semantic understanding via high-quality reconstructions. Furthermore, by fine-tuning a pretrained LLM to decode the intermediate language representations into detailed descriptions, we construct a state-of-the-art (SoTA) captioner comparable to leading models like GPT-4o and Gemini 2.0 Flash. Our method demonstrates exceptional cost-efficiency and significantly reduces data requirements; by primarily utilizing single-modal images for training and maximizing the utility of existing pretrained models (image encoder, T2I diffusion model, and LLM), it circumvents the need for massive paired image-text datasets, keeping the total training expenditure under $1,000 USD.

Accurate interpretation of Electrocardiogram (ECG) signals is pivotal for diagnosing cardiovascular diseases. Integrating ECG signals with their accompanying textual reports holds immense potential to enhance clinical diagnostics through the combination of physiological data and qualitative insights. However, this integration faces significant challenges due to inherent modality disparities and the scarcity of labeled data for robust cross-modal learning. To address these obstacles, we propose C-MELT, a novel framework that pre-trains ECG and text data using a contrastive masked auto-encoder architecture. C-MELT uniquely combines the strengths of generative with enhanced discriminative capabilities to achieve robust cross-modal representations. This is accomplished through masked modality modeling, specialized loss functions, and an improved negative sampling strategy tailored for cross-modal alignment. Extensive experiments on five public datasets across diverse downstream tasks demonstrate that C-MELT significantly outperforms existing methods, achieving 15% and 2% increases in linear probing and zero-shot performance over state-of-the-art models, respectively. These results highlight the effectiveness of C-MELT, underscoring its potential to advance automated clinical diagnostics through multi-modal representations.

This study explores the application of self-supervised learning (SSL) to the task of motion forecasting, an area that has not yet been extensively investigated despite the widespread success of SSL in computer vision and natural language processing. To address this gap, we introduce Forecast-MAE, an extension of the mask autoencoders framework that is specifically designed for self-supervised learning of the motion forecasting task. Our approach includes a novel masking strategy that leverages the strong interconnections between agents' trajectories and road networks, involving complementary masking of agents' future or history trajectories and random masking of lane segments. Our experiments on the challenging Argoverse 2 motion forecasting benchmark show that Forecast-MAE, which utilizes standard Transformer blocks with minimal inductive bias, achieves competitive performance compared to state-of-the-art methods that rely on supervised learning and sophisticated designs. Moreover, it outperforms the previous self-supervised learning method by a significant margin. Code is available at https://github.com/jchengai/forecast-mae.

Variational autoencoders provide a principled framework for learning deep latent-variable models and corresponding inference models. In this work, we provide an introduction to variational autoencoders and some important extensions.

The autoencoder is an unsupervised learning paradigm that aims to create a compact latent representation of data by minimizing the reconstruction loss. However, it tends to overlook the fact that most data (images) are embedded in a lower-dimensional space, which is crucial for effective data representation. To address this limitation, we propose a novel approach called Low-Rank Autoencoder (LoRAE). In LoRAE, we incorporated a low-rank regularizer to adaptively reconstruct a low-dimensional latent space while preserving the basic objective of an autoencoder. This helps embed the data in a lower-dimensional space while preserving important information. It is a simple autoencoder extension that learns low-rank latent space. Theoretically, we establish a tighter error bound for our model. Empirically, our model's superiority shines through various tasks such as image generation and downstream classification. Both theoretical and practical outcomes highlight the importance of acquiring low-dimensional embeddings.

We propose a simple auto-encoder framework for molecule generation. The molecular graph is first encoded into a continuous latent representation z, which is then decoded back to a molecule. The encoding process is easy, but the decoding process remains challenging. In this work, we introduce a simple two-step decoding process. In a first step, a fully connected neural network uses the latent vector z to produce a molecular formula, for example CO_2 (one carbon and two oxygen atoms). In a second step, a graph convolutional neural network uses the same latent vector z to place bonds between the atoms that were produced in the first step (for example a double bond will be placed between the carbon and each of the oxygens). This two-step process, in which a bag of atoms is first generated, and then assembled, provides a simple framework that allows us to develop an efficient molecule auto-encoder. Numerical experiments on basic tasks such as novelty, uniqueness, validity and optimized chemical property for the 250k ZINC molecules demonstrate the performances of the proposed system. Particularly, we achieve the highest reconstruction rate of 90.5\%, improving the previous rate of 76.7\%. We also report the best property improvement results when optimization is constrained by the molecular distance between the original and generated molecules.

This paper presents a novel, fast and privacy preserving implementation of deep autoencoders. DAEF (Deep Autoencoder for Federated learning), unlike traditional neural networks, trains a deep autoencoder network in a non-iterative way, which drastically reduces its training time. Its training can be carried out in a distributed way (several partitions of the dataset in parallel) and incrementally (aggregation of partial models), and due to its mathematical formulation, the data that is exchanged does not endanger the privacy of the users. This makes DAEF a valid method for edge computing and federated learning scenarios. The method has been evaluated and compared to traditional (iterative) deep autoencoders using seven real anomaly detection datasets, and their performance have been shown to be similar despite DAEF's faster training.

Recently, it has been observed that when representations are learnt in a way that encourages sparsity, improved performance is obtained on classification tasks. These methods involve combinations of activation functions, sampling steps and different kinds of penalties. To investigate the effectiveness of sparsity by itself, we propose the k-sparse autoencoder, which is an autoencoder with linear activation function, where in hidden layers only the k highest activities are kept. When applied to the MNIST and NORB datasets, we find that this method achieves better classification results than denoising autoencoders, networks trained with dropout, and RBMs. k-sparse autoencoders are simple to train and the encoding stage is very fast, making them well-suited to large problem sizes, where conventional sparse coding algorithms cannot be applied.

Autoencoder (AE) is the key to the success of latent diffusion models for image and video generation, reducing the denoising resolution and improving efficiency. However, the power of AE has long been underexplored in terms of network design, compression ratio, and training strategy. In this work, we systematically examine the architecture design choices and optimize the computation distribution to obtain a series of efficient and high-compression video AEs that can decode in real time even on mobile devices. We also propose an omni-training objective to unify the design of plain Autoencoder and image-conditioned I2V VAE, achieving multifunctionality in a single VAE network but with enhanced quality. In addition, we propose a novel latent consistency loss that provides stable improvements in reconstruction quality. Latent consistency loss outperforms prior auxiliary losses including LPIPS, GAN and DWT in terms of both quality improvements and simplicity. H3AE achieves ultra-high compression ratios and real-time decoding speed on GPU and mobile, and outperforms prior arts in terms of reconstruction metrics by a large margin. We finally validate our AE by training a DiT on its latent space and demonstrate fast, high-quality text-to-video generation capability.

This work presents a framework based on feature disentanglement to learn speaker embeddings that are robust to environmental variations. Our framework utilises an auto-encoder as a disentangler, dividing the input speaker embedding into components related to the speaker and other residual information. We employ a group of objective functions to ensure that the auto-encoder's code representation - used as the refined embedding - condenses only the speaker characteristics. We show the versatility of our framework through its compatibility with any existing speaker embedding extractor, requiring no structural modifications or adaptations for integration. We validate the effectiveness of our framework by incorporating it into two popularly used embedding extractors and conducting experiments across various benchmarks. The results show a performance improvement of up to 16%. We release our code for this work to be available https://github.com/kaistmm/voxceleb-disentangler

Autoencoders are a popular model in many branches of machine learning and lossy data compression. However, their fundamental limits, the performance of gradient methods and the features learnt during optimization remain poorly understood, even in the two-layer setting. In fact, earlier work has considered either linear autoencoders or specific training regimes (leading to vanishing or diverging compression rates). Our paper addresses this gap by focusing on non-linear two-layer autoencoders trained in the challenging proportional regime in which the input dimension scales linearly with the size of the representation. Our results characterize the minimizers of the population risk, and show that such minimizers are achieved by gradient methods; their structure is also unveiled, thus leading to a concise description of the features obtained via training. For the special case of a sign activation function, our analysis establishes the fundamental limits for the lossy compression of Gaussian sources via (shallow) autoencoders. Finally, while the results are proved for Gaussian data, numerical simulations on standard datasets display the universality of the theoretical predictions.

Deep neural networks are widely used for classification. These deep models often suffer from a lack of interpretability -- they are particularly difficult to understand because of their non-linear nature. As a result, neural networks are often treated as "black box" models, and in the past, have been trained purely to optimize the accuracy of predictions. In this work, we create a novel network architecture for deep learning that naturally explains its own reasoning for each prediction. This architecture contains an autoencoder and a special prototype layer, where each unit of that layer stores a weight vector that resembles an encoded training input. The encoder of the autoencoder allows us to do comparisons within the latent space, while the decoder allows us to visualize the learned prototypes. The training objective has four terms: an accuracy term, a term that encourages every prototype to be similar to at least one encoded input, a term that encourages every encoded input to be close to at least one prototype, and a term that encourages faithful reconstruction by the autoencoder. The distances computed in the prototype layer are used as part of the classification process. Since the prototypes are learned during training, the learned network naturally comes with explanations for each prediction, and the explanations are loyal to what the network actually computes.

Autoencoder networks are unsupervised approaches aiming at combining generative and representational properties by learning simultaneously an encoder-generator map. Although studied extensively, the issues of whether they have the same generative power of GANs, or learn disentangled representations, have not been fully addressed. We introduce an autoencoder that tackles these issues jointly, which we call Adversarial Latent Autoencoder (ALAE). It is a general architecture that can leverage recent improvements on GAN training procedures. We designed two autoencoders: one based on a MLP encoder, and another based on a StyleGAN generator, which we call StyleALAE. We verify the disentanglement properties of both architectures. We show that StyleALAE can not only generate 1024x1024 face images with comparable quality of StyleGAN, but at the same resolution can also produce face reconstructions and manipulations based on real images. This makes ALAE the first autoencoder able to compare with, and go beyond the capabilities of a generator-only type of architecture.

We present a framework for learning disentangled and interpretable jointly continuous and discrete representations in an unsupervised manner. By augmenting the continuous latent distribution of variational autoencoders with a relaxed discrete distribution and controlling the amount of information encoded in each latent unit, we show how continuous and categorical factors of variation can be discovered automatically from data. Experiments show that the framework disentangles continuous and discrete generative factors on various datasets and outperforms current disentangling methods when a discrete generative factor is prominent.