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Dec 12

PaccMann$^{RL}$ on SARS-CoV-2: Designing antiviral candidates with conditional generative models

With the fast development of COVID-19 into a global pandemic, scientists around the globe are desperately searching for effective antiviral therapeutic agents. Bridging systems biology and drug discovery, we propose a deep learning framework for conditional de novo design of antiviral candidate drugs tailored against given protein targets. First, we train a multimodal ligand--protein binding affinity model on predicting affinities of antiviral compounds to target proteins and couple this model with pharmacological toxicity predictors. Exploiting this multi-objective as a reward function of a conditional molecular generator (consisting of two VAEs), we showcase a framework that navigates the chemical space toward regions with more antiviral molecules. Specifically, we explore a challenging setting of generating ligands against unseen protein targets by performing a leave-one-out-cross-validation on 41 SARS-CoV-2-related target proteins. Using deep RL, it is demonstrated that in 35 out of 41 cases, the generation is biased towards sampling more binding ligands, with an average increase of 83% comparing to an unbiased VAE. We present a case-study on a potential Envelope-protein inhibitor and perform a synthetic accessibility assessment of the best generated molecules is performed that resembles a viable roadmap towards a rapid in-vitro evaluation of potential SARS-CoV-2 inhibitors.

  • 7 authors
·
May 27, 2020

mCLM: A Modular Chemical Language Model that Generates Functional and Makeable Molecules

Despite their ability to understand chemical knowledge, large language models (LLMs) remain limited in their capacity to propose novel molecules with desired functions (e.g., drug-like properties). In addition, the molecules that LLMs propose can often be challenging to make, and are almost never compatible with automated synthesis approaches. To better enable the discovery of functional small molecules, LLMs need to learn a new molecular language that is more effective in predicting properties and inherently synced with automated synthesis technology. Current molecule LLMs are limited by representing molecules based on atoms. In this paper, we argue that just like tokenizing texts into meaning-bearing (sub-)word tokens instead of characters, molecules should be tokenized at the level of functional building blocks, i.e., parts of molecules that bring unique functions and serve as effective building blocks for real-world automated laboratory synthesis. This motivates us to propose mCLM, a modular Chemical-Language Model that comprises a bilingual language model that understands both natural language descriptions of functions and molecular blocks. mCLM front-loads synthesizability considerations while improving the predicted functions of molecules in a principled manner. mCLM, with only 3B parameters, achieves improvements in synthetic accessibility relative to 7 other leading generative AI methods including GPT-5. When tested on 122 out-of-distribution medicines using only building blocks/tokens that are compatible with automated modular synthesis, mCLM outperforms all baselines in property scores and synthetic accessibility. mCLM can also reason on multiple functions and iteratively self-improve to rescue drug candidates that failed late in clinical trials ("fallen angels").

  • 14 authors
·
May 18

Breaking Bad Molecules: Are MLLMs Ready for Structure-Level Molecular Detoxification?

Toxicity remains a leading cause of early-stage drug development failure. Despite advances in molecular design and property prediction, the task of molecular toxicity repair - generating structurally valid molecular alternatives with reduced toxicity - has not yet been systematically defined or benchmarked. To fill this gap, we introduce ToxiMol, the first benchmark task for general-purpose Multimodal Large Language Models (MLLMs) focused on molecular toxicity repair. We construct a standardized dataset covering 11 primary tasks and 560 representative toxic molecules spanning diverse mechanisms and granularities. We design a prompt annotation pipeline with mechanism-aware and task-adaptive capabilities, informed by expert toxicological knowledge. In parallel, we propose an automated evaluation framework, ToxiEval, which integrates toxicity endpoint prediction, synthetic accessibility, drug-likeness, and structural similarity into a high-throughput evaluation chain for repair success. We systematically assess nearly 30 mainstream general-purpose MLLMs and design multiple ablation studies to analyze key factors such as evaluation criteria, candidate diversity, and failure attribution. Experimental results show that although current MLLMs still face significant challenges on this task, they begin to demonstrate promising capabilities in toxicity understanding, semantic constraint adherence, and structure-aware molecule editing.

  • 8 authors
·
Jun 12

C5T5: Controllable Generation of Organic Molecules with Transformers

Methods for designing organic materials with desired properties have high potential impact across fields such as medicine, renewable energy, petrochemical engineering, and agriculture. However, using generative modeling to design substances with desired properties is difficult because candidate compounds must satisfy multiple constraints, including synthetic accessibility and other metrics that are intuitive to domain experts but challenging to quantify. We propose C5T5, a novel self-supervised pretraining method that enables transformers to make zero-shot select-and-replace edits, altering organic substances towards desired property values. C5T5 operates on IUPAC names -- a standardized molecular representation that intuitively encodes rich structural information for organic chemists but that has been largely ignored by the ML community. Our technique requires no edited molecule pairs to train and only a rough estimate of molecular properties, and it has the potential to model long-range dependencies and symmetric molecular structures more easily than graph-based methods. C5T5 also provides a powerful interface to domain experts: it grants users fine-grained control over the generative process by selecting and replacing IUPAC name fragments, which enables experts to leverage their intuitions about structure-activity relationships. We demonstrate C5T5's effectiveness on four physical properties relevant for drug discovery, showing that it learns successful and chemically intuitive strategies for altering molecules towards desired property values.

  • 5 authors
·
Aug 23, 2021

Large Language Models and Synthetic Data for Monitoring Dataset Mentions in Research Papers

Tracking how data is mentioned and used in research papers provides critical insights for improving data discoverability, quality, and production. However, manually identifying and classifying dataset mentions across vast academic literature is resource-intensive and not scalable. This paper presents a machine learning framework that automates dataset mention detection across research domains by leveraging large language models (LLMs), synthetic data, and a two-stage fine-tuning process. We employ zero-shot extraction from research papers, an LLM-as-a-Judge for quality assessment, and a reasoning agent for refinement to generate a weakly supervised synthetic dataset. The Phi-3.5-mini instruct model is pre-fine-tuned on this dataset, followed by fine-tuning on a manually annotated subset. At inference, a ModernBERT-based classifier efficiently filters dataset mentions, reducing computational overhead while maintaining high recall. Evaluated on a held-out manually annotated sample, our fine-tuned model outperforms NuExtract-v1.5 and GLiNER-large-v2.1 in dataset extraction accuracy. Our results highlight how LLM-generated synthetic data can effectively address training data scarcity, improving generalization in low-resource settings. This framework offers a pathway toward scalable monitoring of dataset usage, enhancing transparency, and supporting researchers, funders, and policymakers in identifying data gaps and strengthening data accessibility for informed decision-making.

  • 3 authors
·
Feb 14

Preserving Privacy, Increasing Accessibility, and Reducing Cost: An On-Device Artificial Intelligence Model for Medical Transcription and Note Generation

Background: Clinical documentation represents a significant burden for healthcare providers, with physicians spending up to 2 hours daily on administrative tasks. Recent advances in large language models (LLMs) offer promising solutions, but privacy concerns and computational requirements limit their adoption in healthcare settings. Objective: To develop and evaluate a privacy-preserving, on-device medical transcription system using a fine-tuned Llama 3.2 1B model capable of generating structured medical notes from medical transcriptions while maintaining complete data sovereignty entirely in the browser. Methods: We fine-tuned a Llama 3.2 1B model using Parameter-Efficient Fine-Tuning (PEFT) with LoRA on 1,500 synthetic medical transcription-to-structured note pairs. The model was evaluated against the base Llama 3.2 1B on two datasets: 100 endocrinology transcripts and 140 modified ACI benchmark cases. Evaluation employed both statistical metrics (ROUGE, BERTScore, BLEURT) and LLM-as-judge assessments across multiple clinical quality dimensions. Results: The fine-tuned OnDevice model demonstrated substantial improvements over the base model. On the ACI benchmark, ROUGE-1 scores increased from 0.346 to 0.496, while BERTScore F1 improved from 0.832 to 0.866. Clinical quality assessments showed marked reduction in major hallucinations (from 85 to 35 cases) and enhanced factual correctness (2.81 to 3.54 on 5-point scale). Similar improvements were observed on the internal evaluation dataset, with composite scores increasing from 3.13 to 4.43 (+41.5%). Conclusions: Fine-tuning compact LLMs for medical transcription yields clinically meaningful improvements while enabling complete on-device browser deployment. This approach addresses key barriers to AI adoption in healthcare: privacy preservation, cost reduction, and accessibility for resource-constrained environments.

  • 6 authors
·
Jul 2 1

MORDA: A Synthetic Dataset to Facilitate Adaptation of Object Detectors to Unseen Real-target Domain While Preserving Performance on Real-source Domain

Deep neural network (DNN) based perception models are indispensable in the development of autonomous vehicles (AVs). However, their reliance on large-scale, high-quality data is broadly recognized as a burdensome necessity due to the substantial cost of data acquisition and labeling. Further, the issue is not a one-time concern, as AVs might need a new dataset if they are to be deployed to another region (real-target domain) that the in-hand dataset within the real-source domain cannot incorporate. To mitigate this burden, we propose leveraging synthetic environments as an auxiliary domain where the characteristics of real domains are reproduced. This approach could enable indirect experience about the real-target domain in a time- and cost-effective manner. As a practical demonstration of our methodology, nuScenes and South Korea are employed to represent real-source and real-target domains, respectively. That means we construct digital twins for several regions of South Korea, and the data-acquisition framework of nuScenes is reproduced. Blending the aforementioned components within a simulator allows us to obtain a synthetic-fusion domain in which we forge our novel driving dataset, MORDA: Mixture Of Real-domain characteristics for synthetic-data-assisted Domain Adaptation. To verify the value of synthetic features that MORDA provides in learning about driving environments of South Korea, 2D/3D detectors are trained solely on a combination of nuScenes and MORDA. Afterward, their performance is evaluated on the unforeseen real-world dataset (AI-Hub) collected in South Korea. Our experiments present that MORDA can significantly improve mean Average Precision (mAP) on AI-Hub dataset while that on nuScenes is retained or slightly enhanced.

  • 5 authors
·
Jan 8

Automatic Prompt Optimization Techniques: Exploring the Potential for Synthetic Data Generation

Artificial Intelligence (AI) advancement is heavily dependent on access to large-scale, high-quality training data. However, in specialized domains such as healthcare, data acquisition faces significant constraints due to privacy regulations, ethical considerations, and limited availability. While synthetic data generation offers a promising solution, conventional approaches typically require substantial real data for training generative models. The emergence of large-scale prompt-based models presents new opportunities for synthetic data generation without direct access to protected data. However, crafting effective prompts for domain-specific data generation remains challenging, and manual prompt engineering proves insufficient for achieving output with sufficient precision and authenticity. We review recent developments in automatic prompt optimization, following PRISMA guidelines. We analyze six peer-reviewed studies published between 2020 and 2024 that focus on automatic data-free prompt optimization methods. Our analysis reveals three approaches: feedback-driven, error-based, and control-theoretic. Although all approaches demonstrate promising capabilities in prompt refinement and adaptation, our findings suggest the need for an integrated framework that combines complementary optimization techniques to enhance synthetic data generation while minimizing manual intervention. We propose future research directions toward developing robust, iterative prompt optimization frameworks capable of improving the quality of synthetic data. This advancement can be particularly crucial for sensitive fields and in specialized domains where data access is restricted, potentially transforming how we approach synthetic data generation for AI development.

  • 4 authors
·
Feb 5

Exploring the Potential of AI-Generated Synthetic Datasets: A Case Study on Telematics Data with ChatGPT

This research delves into the construction and utilization of synthetic datasets, specifically within the telematics sphere, leveraging OpenAI's powerful language model, ChatGPT. Synthetic datasets present an effective solution to challenges pertaining to data privacy, scarcity, and control over variables - characteristics that make them particularly valuable for research pursuits. The utility of these datasets, however, largely depends on their quality, measured through the lenses of diversity, relevance, and coherence. To illustrate this data creation process, a hands-on case study is conducted, focusing on the generation of a synthetic telematics dataset. The experiment involved an iterative guidance of ChatGPT, progressively refining prompts and culminating in the creation of a comprehensive dataset for a hypothetical urban planning scenario in Columbus, Ohio. Upon generation, the synthetic dataset was subjected to an evaluation, focusing on the previously identified quality parameters and employing descriptive statistics and visualization techniques for a thorough analysis. Despite synthetic datasets not serving as perfect replacements for actual world data, their potential in specific use-cases, when executed with precision, is significant. This research underscores the potential of AI models like ChatGPT in enhancing data availability for complex sectors like telematics, thus paving the way for a myriad of new research opportunities.

  • 1 authors
·
Jun 23, 2023

TactileNet: Bridging the Accessibility Gap with AI-Generated Tactile Graphics for Individuals with Vision Impairment

Tactile graphics are essential for providing access to visual information for the 43 million people globally living with vision loss. Traditional methods for creating these graphics are labor-intensive and cannot meet growing demand. We introduce TactileNet, the first comprehensive dataset and AI-driven framework for generating embossing-ready 2D tactile templates using text-to-image Stable Diffusion (SD) models. By integrating Low-Rank Adaptation (LoRA) and DreamBooth, our method fine-tunes SD models to produce high-fidelity, guideline-compliant graphics while reducing computational costs. Quantitative evaluations with tactile experts show 92.86% adherence to accessibility standards. Structural fidelity analysis revealed near-human design similarity, with an SSIM of 0.538 between generated graphics and expert-designed tactile images. Notably, our method preserves object silhouettes better than human designs (SSIM = 0.259 vs. 0.215 for binary masks), addressing a key limitation of manual tactile abstraction. The framework scales to 32,000 images (7,050 high-quality) across 66 classes, with prompt editing enabling customizable outputs (e.g., adding or removing details). By automating the 2D template generation step-compatible with standard embossing workflows-TactileNet accelerates production while preserving design flexibility. This work demonstrates how AI can augment (not replace) human expertise to bridge the accessibility gap in education and beyond. Code, data, and models will be publicly released to foster further research.

  • 5 authors
·
Apr 7

Revisit Large-Scale Image-Caption Data in Pre-training Multimodal Foundation Models

Recent advancements in multimodal models highlight the value of rewritten captions for improving performance, yet key challenges remain. For example, while synthetic captions often provide superior quality and image-text alignment, it is not clear whether they can fully replace AltTexts: the role of synthetic captions and their interaction with original web-crawled AltTexts in pre-training is still not well understood. Moreover, different multimodal foundation models may have unique preferences for specific caption formats, but efforts to identify the optimal captions for each model remain limited. In this work, we propose a novel, controllable, and scalable captioning pipeline designed to generate diverse caption formats tailored to various multimodal models. By examining Short Synthetic Captions (SSC) towards Dense Synthetic Captions (DSC+) as case studies, we systematically explore their effects and interactions with AltTexts across models such as CLIP, multimodal LLMs, and diffusion models. Our findings reveal that a hybrid approach that keeps both synthetic captions and AltTexts can outperform the use of synthetic captions alone, improving both alignment and performance, with each model demonstrating preferences for particular caption formats. This comprehensive analysis provides valuable insights into optimizing captioning strategies, thereby advancing the pre-training of multimodal foundation models.

  • 12 authors
·
Oct 3, 2024 2

Screen2AX: Vision-Based Approach for Automatic macOS Accessibility Generation

Desktop accessibility metadata enables AI agents to interpret screens and supports users who depend on tools like screen readers. Yet, many applications remain largely inaccessible due to incomplete or missing metadata provided by developers - our investigation shows that only 33% of applications on macOS offer full accessibility support. While recent work on structured screen representation has primarily addressed specific challenges, such as UI element detection or captioning, none has attempted to capture the full complexity of desktop interfaces by replicating their entire hierarchical structure. To bridge this gap, we introduce Screen2AX, the first framework to automatically create real-time, tree-structured accessibility metadata from a single screenshot. Our method uses vision-language and object detection models to detect, describe, and organize UI elements hierarchically, mirroring macOS's system-level accessibility structure. To tackle the limited availability of data for macOS desktop applications, we compiled and publicly released three datasets encompassing 112 macOS applications, each annotated for UI element detection, grouping, and hierarchical accessibility metadata alongside corresponding screenshots. Screen2AX accurately infers hierarchy trees, achieving a 77% F1 score in reconstructing a complete accessibility tree. Crucially, these hierarchy trees improve the ability of autonomous agents to interpret and interact with complex desktop interfaces. We introduce Screen2AX-Task, a benchmark specifically designed for evaluating autonomous agent task execution in macOS desktop environments. Using this benchmark, we demonstrate that Screen2AX delivers a 2.2x performance improvement over native accessibility representations and surpasses the state-of-the-art OmniParser V2 system on the ScreenSpot benchmark.

  • 5 authors
·
Jul 22

A New Benchmark: On the Utility of Synthetic Data with Blender for Bare Supervised Learning and Downstream Domain Adaptation

Deep learning in computer vision has achieved great success with the price of large-scale labeled training data. However, exhaustive data annotation is impracticable for each task of all domains of interest, due to high labor costs and unguaranteed labeling accuracy. Besides, the uncontrollable data collection process produces non-IID training and test data, where undesired duplication may exist. All these nuisances may hinder the verification of typical theories and exposure to new findings. To circumvent them, an alternative is to generate synthetic data via 3D rendering with domain randomization. We in this work push forward along this line by doing profound and extensive research on bare supervised learning and downstream domain adaptation. Specifically, under the well-controlled, IID data setting enabled by 3D rendering, we systematically verify the typical, important learning insights, e.g., shortcut learning, and discover the new laws of various data regimes and network architectures in generalization. We further investigate the effect of image formation factors on generalization, e.g., object scale, material texture, illumination, camera viewpoint, and background in a 3D scene. Moreover, we use the simulation-to-reality adaptation as a downstream task for comparing the transferability between synthetic and real data when used for pre-training, which demonstrates that synthetic data pre-training is also promising to improve real test results. Lastly, to promote future research, we develop a new large-scale synthetic-to-real benchmark for image classification, termed S2RDA, which provides more significant challenges for transfer from simulation to reality. The code and datasets are available at https://github.com/huitangtang/On_the_Utility_of_Synthetic_Data.

  • 2 authors
·
Mar 16, 2023

From Fake to Real: Pretraining on Balanced Synthetic Images to Prevent Spurious Correlations in Image Recognition

Visual recognition models are prone to learning spurious correlations induced by a biased training set where certain conditions B (\eg, Indoors) are over-represented in certain classes Y (\eg, Big Dogs). Synthetic data from off-the-shelf large-scale generative models offers a promising direction to mitigate this issue by augmenting underrepresented subgroups in the real dataset. However, by using a mixed distribution of real and synthetic data, we introduce another source of bias due to distributional differences between synthetic and real data (\eg synthetic artifacts). As we will show, prior work's approach for using synthetic data to resolve the model's bias toward B do not correct the model's bias toward the pair (B, G), where G denotes whether the sample is real or synthetic. Thus, the model could simply learn signals based on the pair (B, G) (\eg, Synthetic Indoors) to make predictions about Y (\eg, Big Dogs). To address this issue, we propose a simple, easy-to-implement, two-step training pipeline that we call From Fake to Real (FFR). The first step of FFR pre-trains a model on balanced synthetic data to learn robust representations across subgroups. In the second step, FFR fine-tunes the model on real data using ERM or common loss-based bias mitigation methods. By training on real and synthetic data separately, FFR does not expose the model to the statistical differences between real and synthetic data and thus avoids the issue of bias toward the pair (B, G). Our experiments show that FFR improves worst group accuracy over the state-of-the-art by up to 20\% over three datasets. Code available: https://github.com/mqraitem/From-Fake-to-Real

  • 3 authors
·
Aug 8, 2023

Rethinking Driving World Model as Synthetic Data Generator for Perception Tasks

Recent advancements in driving world models enable controllable generation of high-quality RGB videos or multimodal videos. Existing methods primarily focus on metrics related to generation quality and controllability. However, they often overlook the evaluation of downstream perception tasks, which are really crucial for the performance of autonomous driving. Existing methods usually leverage a training strategy that first pretrains on synthetic data and finetunes on real data, resulting in twice the epochs compared to the baseline (real data only). When we double the epochs in the baseline, the benefit of synthetic data becomes negligible. To thoroughly demonstrate the benefit of synthetic data, we introduce Dream4Drive, a novel synthetic data generation framework designed for enhancing the downstream perception tasks. Dream4Drive first decomposes the input video into several 3D-aware guidance maps and subsequently renders the 3D assets onto these guidance maps. Finally, the driving world model is fine-tuned to produce the edited, multi-view photorealistic videos, which can be used to train the downstream perception models. Dream4Drive enables unprecedented flexibility in generating multi-view corner cases at scale, significantly boosting corner case perception in autonomous driving. To facilitate future research, we also contribute a large-scale 3D asset dataset named DriveObj3D, covering the typical categories in driving scenarios and enabling diverse 3D-aware video editing. We conduct comprehensive experiments to show that Dream4Drive can effectively boost the performance of downstream perception models under various training epochs. Page: https://wm-research.github.io/Dream4Drive/ GitHub Link: https://github.com/wm-research/Dream4Drive

BEHAVIOR Vision Suite: Customizable Dataset Generation via Simulation

The systematic evaluation and understanding of computer vision models under varying conditions require large amounts of data with comprehensive and customized labels, which real-world vision datasets rarely satisfy. While current synthetic data generators offer a promising alternative, particularly for embodied AI tasks, they often fall short for computer vision tasks due to low asset and rendering quality, limited diversity, and unrealistic physical properties. We introduce the BEHAVIOR Vision Suite (BVS), a set of tools and assets to generate fully customized synthetic data for systematic evaluation of computer vision models, based on the newly developed embodied AI benchmark, BEHAVIOR-1K. BVS supports a large number of adjustable parameters at the scene level (e.g., lighting, object placement), the object level (e.g., joint configuration, attributes such as "filled" and "folded"), and the camera level (e.g., field of view, focal length). Researchers can arbitrarily vary these parameters during data generation to perform controlled experiments. We showcase three example application scenarios: systematically evaluating the robustness of models across different continuous axes of domain shift, evaluating scene understanding models on the same set of images, and training and evaluating simulation-to-real transfer for a novel vision task: unary and binary state prediction. Project website: https://behavior-vision-suite.github.io/

  • 23 authors
·
May 15, 2024

MATE: LLM-Powered Multi-Agent Translation Environment for Accessibility Applications

Accessibility remains a critical concern in today's society, as many technologies are not developed to support the full range of user needs. Existing multi-agent systems (MAS) often cannot provide comprehensive assistance for users in need due to the lack of customization stemming from closed-source designs. Consequently, individuals with disabilities frequently encounter significant barriers when attempting to interact with digital environments. We introduce MATE, a multimodal accessibility MAS, which performs the modality conversions based on the user's needs. The system is useful for assisting people with disabilities by ensuring that data will be converted to an understandable format. For instance, if the user cannot see well and receives an image, the system converts this image to its audio description. MATE can be applied to a wide range of domains, industries, and areas, such as healthcare, and can become a useful assistant for various groups of users. The system supports multiple types of models, ranging from LLM API calling to using custom machine learning (ML) classifiers. This flexibility ensures that the system can be adapted to various needs and is compatible with a wide variety of hardware. Since the system is expected to run locally, it ensures the privacy and security of sensitive information. In addition, the framework can be effectively integrated with institutional technologies (e.g., digital healthcare service) for real-time user assistance. Furthermore, we introduce ModCon-Task-Identifier, a model that is capable of extracting the precise modality conversion task from the user input. Numerous experiments show that ModCon-Task-Identifier consistently outperforms other LLMs and statistical models on our custom data. Our code and data are publicly available at https://github.com/AlgazinovAleksandr/Multi-Agent-MATE.

  • 3 authors
·
Jun 24 1

AUGCAL: Improving Sim2Real Adaptation by Uncertainty Calibration on Augmented Synthetic Images

Synthetic data (SIM) drawn from simulators have emerged as a popular alternative for training models where acquiring annotated real-world images is difficult. However, transferring models trained on synthetic images to real-world applications can be challenging due to appearance disparities. A commonly employed solution to counter this SIM2REAL gap is unsupervised domain adaptation, where models are trained using labeled SIM data and unlabeled REAL data. Mispredictions made by such SIM2REAL adapted models are often associated with miscalibration - stemming from overconfident predictions on real data. In this paper, we introduce AUGCAL, a simple training-time patch for unsupervised adaptation that improves SIM2REAL adapted models by - (1) reducing overall miscalibration, (2) reducing overconfidence in incorrect predictions and (3) improving confidence score reliability by better guiding misclassification detection - all while retaining or improving SIM2REAL performance. Given a base SIM2REAL adaptation algorithm, at training time, AUGCAL involves replacing vanilla SIM images with strongly augmented views (AUG intervention) and additionally optimizing for a training time calibration loss on augmented SIM predictions (CAL intervention). We motivate AUGCAL using a brief analytical justification of how to reduce miscalibration on unlabeled REAL data. Through our experiments, we empirically show the efficacy of AUGCAL across multiple adaptation methods, backbones, tasks and shifts.

  • 5 authors
·
Dec 10, 2023

LOKI: A Comprehensive Synthetic Data Detection Benchmark using Large Multimodal Models

With the rapid development of AI-generated content, the future internet may be inundated with synthetic data, making the discrimination of authentic and credible multimodal data increasingly challenging. Synthetic data detection has thus garnered widespread attention, and the performance of large multimodal models (LMMs) in this task has attracted significant interest. LMMs can provide natural language explanations for their authenticity judgments, enhancing the explainability of synthetic content detection. Simultaneously, the task of distinguishing between real and synthetic data effectively tests the perception, knowledge, and reasoning capabilities of LMMs. In response, we introduce LOKI, a novel benchmark designed to evaluate the ability of LMMs to detect synthetic data across multiple modalities. LOKI encompasses video, image, 3D, text, and audio modalities, comprising 18K carefully curated questions across 26 subcategories with clear difficulty levels. The benchmark includes coarse-grained judgment and multiple-choice questions, as well as fine-grained anomaly selection and explanation tasks, allowing for a comprehensive analysis of LMMs. We evaluated 22 open-source LMMs and 6 closed-source models on LOKI, highlighting their potential as synthetic data detectors and also revealing some limitations in the development of LMM capabilities. More information about LOKI can be found at https://opendatalab.github.io/LOKI/

  • 15 authors
·
Oct 13, 2024 4

RealGen: Retrieval Augmented Generation for Controllable Traffic Scenarios

Simulation plays a crucial role in the development of autonomous vehicles (AVs) due to the potential risks associated with real-world testing. Although significant progress has been made in the visual aspects of simulators, generating complex behavior among agents remains a formidable challenge. It is not only imperative to ensure realism in the scenarios generated but also essential to incorporate preferences and conditions to facilitate controllable generation for AV training and evaluation. Traditional methods, mainly relying on memorizing the distribution of training datasets, often fall short in generating unseen scenarios. Inspired by the success of retrieval augmented generation in large language models, we present RealGen, a novel retrieval-based in-context learning framework for traffic scenario generation. RealGen synthesizes new scenarios by combining behaviors from multiple retrieved examples in a gradient-free way, which may originate from templates or tagged scenarios. This in-context learning framework endows versatile generative capabilities, including the ability to edit scenarios, compose various behaviors, and produce critical scenarios. Evaluations show that RealGen offers considerable flexibility and controllability, marking a new direction in the field of controllable traffic scenario generation. Check our project website for more information: https://realgen.github.io.

  • 5 authors
·
Dec 19, 2023

SynLLM: A Comparative Analysis of Large Language Models for Medical Tabular Synthetic Data Generation via Prompt Engineering

Access to real-world medical data is often restricted due to privacy regulations, posing a significant barrier to the advancement of healthcare research. Synthetic data offers a promising alternative; however, generating realistic, clinically valid, and privacy-conscious records remains a major challenge. Recent advancements in Large Language Models (LLMs) offer new opportunities for structured data generation; however, existing approaches frequently lack systematic prompting strategies and comprehensive, multi-dimensional evaluation frameworks. In this paper, we present SynLLM, a modular framework for generating high-quality synthetic medical tabular data using 20 state-of-the-art open-source LLMs, including LLaMA, Mistral, and GPT variants, guided by structured prompts. We propose four distinct prompt types, ranging from example-driven to rule-based constraints, that encode schema, metadata, and domain knowledge to control generation without model fine-tuning. Our framework features a comprehensive evaluation pipeline that rigorously assesses generated data across statistical fidelity, clinical consistency, and privacy preservation. We evaluate SynLLM across three public medical datasets, including Diabetes, Cirrhosis, and Stroke, using 20 open-source LLMs. Our results show that prompt engineering significantly impacts data quality and privacy risk, with rule-based prompts achieving the best privacy-quality balance. SynLLM establishes that, when guided by well-designed prompts and evaluated with robust, multi-metric criteria, LLMs can generate synthetic medical data that is both clinically plausible and privacy-aware, paving the way for safer and more effective data sharing in healthcare research.

  • 3 authors
·
Aug 11

LLM See, LLM Do: Guiding Data Generation to Target Non-Differentiable Objectives

The widespread adoption of synthetic data raises new questions about how models generating the data can influence other large language models (LLMs) via distilled data. To start, our work exhaustively characterizes the impact of passive inheritance of model properties by systematically studying the consequences of synthetic data integration. We provide one of the most comprehensive studies to-date of how the source of synthetic data shapes models' internal biases, calibration and generations' textual attributes and preferences. We find that models are surprisingly sensitive towards certain attributes even when the synthetic data prompts appear "neutral". which invites the question whether this sensitivity can be exploited for good. Our findings invite the question can we explicitly steer the models towards the properties we want at test time by exploiting the data generation process? This would have historically been considered infeasible due to the cost of collecting data with a specific characteristic or objective in mind. However, improvement in the quality of synthetic data, as well as a shift towards general-purpose models designed to follow a diverse way of instructions, means this question is timely. We propose active inheritance as a term to describe intentionally constraining synthetic data according to a non-differentiable objective. We demonstrate how active inheritance can steer the generation profiles of models towards desirable non-differentiable attributes, e.g. high lexical diversity or low toxicity.

  • 5 authors
·
Jul 1, 2024

EgoGen: An Egocentric Synthetic Data Generator

Understanding the world in first-person view is fundamental in Augmented Reality (AR). This immersive perspective brings dramatic visual changes and unique challenges compared to third-person views. Synthetic data has empowered third-person-view vision models, but its application to embodied egocentric perception tasks remains largely unexplored. A critical challenge lies in simulating natural human movements and behaviors that effectively steer the embodied cameras to capture a faithful egocentric representation of the 3D world. To address this challenge, we introduce EgoGen, a new synthetic data generator that can produce accurate and rich ground-truth training data for egocentric perception tasks. At the heart of EgoGen is a novel human motion synthesis model that directly leverages egocentric visual inputs of a virtual human to sense the 3D environment. Combined with collision-avoiding motion primitives and a two-stage reinforcement learning approach, our motion synthesis model offers a closed-loop solution where the embodied perception and movement of the virtual human are seamlessly coupled. Compared to previous works, our model eliminates the need for a pre-defined global path, and is directly applicable to dynamic environments. Combined with our easy-to-use and scalable data generation pipeline, we demonstrate EgoGen's efficacy in three tasks: mapping and localization for head-mounted cameras, egocentric camera tracking, and human mesh recovery from egocentric views. EgoGen will be fully open-sourced, offering a practical solution for creating realistic egocentric training data and aiming to serve as a useful tool for egocentric computer vision research. Refer to our project page: https://ego-gen.github.io/.

  • 8 authors
·
Jan 16, 2024

Conditional Data Synthesis Augmentation

Reliable machine learning and statistical analysis rely on diverse, well-distributed training data. However, real-world datasets are often limited in size and exhibit underrepresentation across key subpopulations, leading to biased predictions and reduced performance, particularly in supervised tasks such as classification. To address these challenges, we propose Conditional Data Synthesis Augmentation (CoDSA), a novel framework that leverages generative models, such as diffusion models, to synthesize high-fidelity data for improving model performance across multimodal domains including tabular, textual, and image data. CoDSA generates synthetic samples that faithfully capture the conditional distributions of the original data, with a focus on under-sampled or high-interest regions. Through transfer learning, CoDSA fine-tunes pre-trained generative models to enhance the realism of synthetic data and increase sample density in sparse areas. This process preserves inter-modal relationships, mitigates data imbalance, improves domain adaptation, and boosts generalization. We also introduce a theoretical framework that quantifies the statistical accuracy improvements enabled by CoDSA as a function of synthetic sample volume and targeted region allocation, providing formal guarantees of its effectiveness. Extensive experiments demonstrate that CoDSA consistently outperforms non-adaptive augmentation strategies and state-of-the-art baselines in both supervised and unsupervised settings.

  • 2 authors
·
Apr 9

A Multi-Faceted Evaluation Framework for Assessing Synthetic Data Generated by Large Language Models

The rapid advancements in generative AI and large language models (LLMs) have opened up new avenues for producing synthetic data, particularly in the realm of structured tabular formats, such as product reviews. Despite the potential benefits, concerns regarding privacy leakage have surfaced, especially when personal information is utilized in the training datasets. In addition, there is an absence of a comprehensive evaluation framework capable of quantitatively measuring the quality of the generated synthetic data and their utility for downstream tasks. In response to this gap, we introduce SynEval, an open-source evaluation framework designed to assess the fidelity, utility, and privacy preservation of synthetically generated tabular data via a suite of diverse evaluation metrics. We validate the efficacy of our proposed framework - SynEval - by applying it to synthetic product review data generated by three state-of-the-art LLMs: ChatGPT, Claude, and Llama. Our experimental findings illuminate the trade-offs between various evaluation metrics in the context of synthetic data generation. Furthermore, SynEval stands as a critical instrument for researchers and practitioners engaged with synthetic tabular data,, empowering them to judiciously determine the suitability of the generated data for their specific applications, with an emphasis on upholding user privacy.

  • 3 authors
·
Apr 20, 2024

SOS: Synthetic Object Segments Improve Detection, Segmentation, and Grounding

Visual grouping -- operationalized via instance segmentation, visual grounding, and object detection -- underpins applications from robotic perception to photo editing. Large annotated datasets are costly, biased in coverage, and hard to scale. Synthetic data are promising but often lack flexibility, accuracy, and compositional diversity. We present SOS, a simple and scalable data synthesis pipeline based on an object-centric composition strategy. It pastes high-quality synthetic object segments into new images using structured layout priors and generative relighting, producing accurate and diverse masks, boxes, and referring expressions. Models trained on 100000 synthetic images from SOS outperform those trained on larger real-image datasets such as GRIT (20M) and V3Det (200K) on detection and grounding tasks, achieving +10.9 AP on LVIS detection and +8.4 N_{Acc} on gRefCOCO grounding. SOS enables controllable dataset construction and improves generalization in both low-data and closed-vocabulary settings. Augmenting LVIS and COCO with synthetic object segments yields strong performance across real-data scales and even larger gains under extremely limited real data (for example, +3.83 AP_{rare} on LVIS instance segmentation and +6.59 AP with a 1 percent COCO setup). This controllability also supports targeted data generation for challenging intra-class referring in visual grounding.

  • 7 authors
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Oct 10

Synatra: Turning Indirect Knowledge into Direct Demonstrations for Digital Agents at Scale

LLMs can now act as autonomous agents that interact with digital environments and complete specific objectives (e.g., arranging an online meeting). However, accuracy is still far from satisfactory, partly due to a lack of large-scale, direct demonstrations for digital tasks. Obtaining supervised data from humans is costly, and automatic data collection through exploration or reinforcement learning relies on complex environmental and content setup, resulting in datasets that lack comprehensive coverage of various scenarios. On the other hand, there is abundant knowledge that may indirectly assist task completion, such as online tutorials that were created for human consumption. In this work, we present Synatra, an approach that effectively transforms this indirect knowledge into direct supervision at scale. We define different types of indirect knowledge, and carefully study the available sources to obtain it, methods to encode the structure of direct demonstrations, and finally methods to transform indirect knowledge into direct demonstrations. We use 100k such synthetically-created demonstrations to finetune a 7B CodeLlama, and demonstrate that the resulting agent surpasses all comparably sized models on three web-based task benchmarks Mind2Web, MiniWoB++ and WebArena, as well as surpassing GPT-3.5 on WebArena and Mind2Web. In addition, while synthetic demonstrations prove to be only 3% the cost of human demonstrations (at $0.031 each), we show that the synthetic demonstrations can be more effective than an identical number of human demonstrations collected from limited domains.

  • 10 authors
·
Sep 23, 2024

Category-Level 6D Object Pose and Size Estimation using Self-Supervised Deep Prior Deformation Networks

It is difficult to precisely annotate object instances and their semantics in 3D space, and as such, synthetic data are extensively used for these tasks, e.g., category-level 6D object pose and size estimation. However, the easy annotations in synthetic domains bring the downside effect of synthetic-to-real (Sim2Real) domain gap. In this work, we aim to address this issue in the task setting of Sim2Real, unsupervised domain adaptation for category-level 6D object pose and size estimation. We propose a method that is built upon a novel Deep Prior Deformation Network, shortened as DPDN. DPDN learns to deform features of categorical shape priors to match those of object observations, and is thus able to establish deep correspondence in the feature space for direct regression of object poses and sizes. To reduce the Sim2Real domain gap, we formulate a novel self-supervised objective upon DPDN via consistency learning; more specifically, we apply two rigid transformations to each object observation in parallel, and feed them into DPDN respectively to yield dual sets of predictions; on top of the parallel learning, an inter-consistency term is employed to keep cross consistency between dual predictions for improving the sensitivity of DPDN to pose changes, while individual intra-consistency ones are used to enforce self-adaptation within each learning itself. We train DPDN on both training sets of the synthetic CAMERA25 and real-world REAL275 datasets; our results outperform the existing methods on REAL275 test set under both the unsupervised and supervised settings. Ablation studies also verify the efficacy of our designs. Our code is released publicly at https://github.com/JiehongLin/Self-DPDN.

  • 4 authors
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Jul 12, 2022

InternData-A1: Pioneering High-Fidelity Synthetic Data for Pre-training Generalist Policy

Recent works explore how real and synthetic data contribute to Vision-Language-Action (VLA) models' generalization. While current VLA models have shown the strong effectiveness of large-scale real-robot pre-training, synthetic data has not previously demonstrated comparable capability at scale. This paper provides the first evidence that synthetic data alone can match the performance of the strongest π-dataset in pre-training a VLA model, revealing the substantial value of large-scale simulation. The resulting model also exhibits surprisingly zero-shot sim-to-real transfer on several challenging tasks. Our synthetic dataset, InternData-A1, contains over 630k trajectories and 7,433 hours across 4 embodiments, 18 skills, 70 tasks, and 227 scenes, covering rigid, articulated, deformable, and fluid-object manipulation. It is generated through a highly autonomous, fully decoupled, and compositional simulation pipeline that enables long-horizon skill composition, flexible task assembly, and heterogeneous embodiments with minimal manual tuning. Using the same architecture as π_0, we pre-train a model entirely on InternData-A1 and find that it matches the official π_0 across 49 simulation tasks, 5 real-world tasks, and 4 long-horizon dexterous tasks. We release the dataset and will open-source the generation pipeline to broaden access to large-scale robotic data and to lower the barrier to scalable data creation for embodied AI research.

  • 16 authors
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Nov 20

Comprehensive Analysis of Transparency and Accessibility of ChatGPT, DeepSeek, And other SoTA Large Language Models

Despite increasing discussions on open-source Artificial Intelligence (AI), existing research lacks a discussion on the transparency and accessibility of state-of-the-art (SoTA) Large Language Models (LLMs). The Open Source Initiative (OSI) has recently released its first formal definition of open-source software. This definition, when combined with standard dictionary definitions and the sparse published literature, provide an initial framework to support broader accessibility to AI models such as LLMs, but more work is essential to capture the unique dynamics of openness in AI. In addition, concerns about open-washing, where models claim openness but lack full transparency, has been raised, which limits the reproducibility, bias mitigation, and domain adaptation of these models. In this context, our study critically analyzes SoTA LLMs from the last five years, including ChatGPT, DeepSeek, LLaMA, and others, to assess their adherence to transparency standards and the implications of partial openness. Specifically, we examine transparency and accessibility from two perspectives: open-source vs. open-weight models. Our findings reveal that while some models are labeled as open-source, this does not necessarily mean they are fully open-sourced. Even in the best cases, open-source models often do not report model training data, and code as well as key metrics, such as weight accessibility, and carbon emissions. To the best of our knowledge, this is the first study that systematically examines the transparency and accessibility of over 100 different SoTA LLMs through the dual lens of open-source and open-weight models. The findings open avenues for further research and call for responsible and sustainable AI practices to ensure greater transparency, accountability, and ethical deployment of these models.(DeepSeek transparency, ChatGPT accessibility, open source, DeepSeek open source)

  • 3 authors
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Feb 21

Differentially Private Synthetic Data via Foundation Model APIs 2: Text

Text data has become extremely valuable due to the emergence of machine learning algorithms that learn from it. A lot of high-quality text data generated in the real world is private and therefore cannot be shared or used freely due to privacy concerns. Generating synthetic replicas of private text data with a formal privacy guarantee, i.e., differential privacy (DP), offers a promising and scalable solution. However, existing methods necessitate DP finetuning of large language models (LLMs) on private data to generate DP synthetic data. This approach is not viable for proprietary LLMs (e.g., GPT-3.5) and also demands considerable computational resources for open-source LLMs. Lin et al. (2024) recently introduced the Private Evolution (PE) algorithm to generate DP synthetic images with only API access to diffusion models. In this work, we propose an augmented PE algorithm, named Aug-PE, that applies to the complex setting of text. We use API access to an LLM and generate DP synthetic text without any model training. We conduct comprehensive experiments on three benchmark datasets. Our results demonstrate that Aug-PE produces DP synthetic text that yields competitive utility with the SOTA DP finetuning baselines. This underscores the feasibility of relying solely on API access of LLMs to produce high-quality DP synthetic texts, thereby facilitating more accessible routes to privacy-preserving LLM applications. Our code and data are available at https://github.com/AI-secure/aug-pe.

  • 12 authors
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Mar 4, 2024

SonicSim: A customizable simulation platform for speech processing in moving sound source scenarios

The systematic evaluation of speech separation and enhancement models under moving sound source conditions typically requires extensive data comprising diverse scenarios. However, real-world datasets often contain insufficient data to meet the training and evaluation requirements of models. Although synthetic datasets offer a larger volume of data, their acoustic simulations lack realism. Consequently, neither real-world nor synthetic datasets effectively fulfill practical needs. To address these issues, we introduce SonicSim, a synthetic toolkit de-designed to generate highly customizable data for moving sound sources. SonicSim is developed based on the embodied AI simulation platform, Habitat-sim, supporting multi-level adjustments, including scene-level, microphone-level, and source-level, thereby generating more diverse synthetic data. Leveraging SonicSim, we constructed a moving sound source benchmark dataset, SonicSet, using the Librispeech, the Freesound Dataset 50k (FSD50K) and Free Music Archive (FMA), and 90 scenes from the Matterport3D to evaluate speech separation and enhancement models. Additionally, to validate the differences between synthetic data and real-world data, we randomly selected 5 hours of raw data without reverberation from the SonicSet validation set to record a real-world speech separation dataset, which was then compared with the corresponding synthetic datasets. Similarly, we utilized the real-world speech enhancement dataset RealMAN to validate the acoustic gap between other synthetic datasets and the SonicSet dataset for speech enhancement. The results indicate that the synthetic data generated by SonicSim can effectively generalize to real-world scenarios. Demo and code are publicly available at https://cslikai.cn/SonicSim/.

  • 6 authors
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Oct 2, 2024 2

NaturalL2S: End-to-End High-quality Multispeaker Lip-to-Speech Synthesis with Differential Digital Signal Processing

Recent advancements in visual speech recognition (VSR) have promoted progress in lip-to-speech synthesis, where pre-trained VSR models enhance the intelligibility of synthesized speech by providing valuable semantic information. The success achieved by cascade frameworks, which combine pseudo-VSR with pseudo-text-to-speech (TTS) or implicitly utilize the transcribed text, highlights the benefits of leveraging VSR models. However, these methods typically rely on mel-spectrograms as an intermediate representation, which may introduce a key bottleneck: the domain gap between synthetic mel-spectrograms, generated from inherently error-prone lip-to-speech mappings, and real mel-spectrograms used to train vocoders. This mismatch inevitably degrades synthesis quality. To bridge this gap, we propose Natural Lip-to-Speech (NaturalL2S), an end-to-end framework integrating acoustic inductive biases with differentiable speech generation components. Specifically, we introduce a fundamental frequency (F0) predictor to capture prosodic variations in synthesized speech. The predicted F0 then drives a Differentiable Digital Signal Processing (DDSP) synthesizer to generate a coarse signal which serves as prior information for subsequent speech synthesis. Additionally, instead of relying on a reference speaker embedding as an auxiliary input, our approach achieves satisfactory performance on speaker similarity without explicitly modelling speaker characteristics. Both objective and subjective evaluation results demonstrate that NaturalL2S can effectively enhance the quality of the synthesized speech when compared to state-of-the-art methods. Our demonstration page is accessible at https://yifan-liang.github.io/NaturalL2S/.

  • 5 authors
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Feb 17 1

AgentInstruct: Toward Generative Teaching with Agentic Flows

Synthetic data is becoming increasingly important for accelerating the development of language models, both large and small. Despite several successful use cases, researchers also raised concerns around model collapse and drawbacks of imitating other models. This discrepancy can be attributed to the fact that synthetic data varies in quality and diversity. Effective use of synthetic data usually requires significant human effort in curating the data. We focus on using synthetic data for post-training, specifically creating data by powerful models to teach a new skill or behavior to another model, we refer to this setting as Generative Teaching. We introduce AgentInstruct, an extensible agentic framework for automatically creating large amounts of diverse and high-quality synthetic data. AgentInstruct can create both the prompts and responses, using only raw data sources like text documents and code files as seeds. We demonstrate the utility of AgentInstruct by creating a post training dataset of 25M pairs to teach language models different skills, such as text editing, creative writing, tool usage, coding, reading comprehension, etc. The dataset can be used for instruction tuning of any base model. We post-train Mistral-7b with the data. When comparing the resulting model Orca-3 to Mistral-7b-Instruct (which uses the same base model), we observe significant improvements across many benchmarks. For example, 40% improvement on AGIEval, 19% improvement on MMLU, 54% improvement on GSM8K, 38% improvement on BBH and 45% improvement on AlpacaEval. Additionally, it consistently outperforms other models such as LLAMA-8B-instruct and GPT-3.5-turbo.

  • 14 authors
·
Jul 3, 2024 16

Scaling Laws of Synthetic Data for Language Models

Large language models (LLMs) achieve strong performance across diverse tasks, largely driven by high-quality web data used in pre-training. However, recent studies indicate this data source is rapidly depleting. Synthetic data emerges as a promising alternative, but it remains unclear whether synthetic datasets exhibit predictable scalability comparable to raw pre-training data. In this work, we systematically investigate the scaling laws of synthetic data by introducing SynthLLM, a scalable framework that transforms pre-training corpora into diverse, high-quality synthetic datasets. Our approach achieves this by automatically extracting and recombining high-level concepts across multiple documents using a graph algorithm. Key findings from our extensive mathematical experiments on SynthLLM include: (1) SynthLLM generates synthetic data that reliably adheres to the rectified scaling law across various model sizes; (2) Performance improvements plateau near 300B tokens; and (3) Larger models approach optimal performance with fewer training tokens. For instance, an 8B model peaks at 1T tokens, while a 3B model requires 4T. Moreover, comparisons with existing synthetic data generation and augmentation methods demonstrate that SynthLLM achieves superior performance and scalability. Our findings highlight synthetic data as a scalable and reliable alternative to organic pre-training corpora, offering a viable path toward continued improvement in model performance.

  • 13 authors
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Mar 25

RAP: 3D Rasterization Augmented End-to-End Planning

Imitation learning for end-to-end driving trains policies only on expert demonstrations. Once deployed in a closed loop, such policies lack recovery data: small mistakes cannot be corrected and quickly compound into failures. A promising direction is to generate alternative viewpoints and trajectories beyond the logged path. Prior work explores photorealistic digital twins via neural rendering or game engines, but these methods are prohibitively slow and costly, and thus mainly used for evaluation. In this work, we argue that photorealism is unnecessary for training end-to-end planners. What matters is semantic fidelity and scalability: driving depends on geometry and dynamics, not textures or lighting. Motivated by this, we propose 3D Rasterization, which replaces costly rendering with lightweight rasterization of annotated primitives, enabling augmentations such as counterfactual recovery maneuvers and cross-agent view synthesis. To transfer these synthetic views effectively to real-world deployment, we introduce a Raster-to-Real feature-space alignment that bridges the sim-to-real gap. Together, these components form Rasterization Augmented Planning (RAP), a scalable data augmentation pipeline for planning. RAP achieves state-of-the-art closed-loop robustness and long-tail generalization, ranking first on four major benchmarks: NAVSIM v1/v2, Waymo Open Dataset Vision-based E2E Driving, and Bench2Drive. Our results show that lightweight rasterization with feature alignment suffices to scale E2E training, offering a practical alternative to photorealistic rendering. Project page: https://alan-lanfeng.github.io/RAP/.

  • 8 authors
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Oct 5

Generative AI for learning: Investigating the potential of synthetic learning videos

Recent advances in generative artificial intelligence (AI) have captured worldwide attention. Tools such as Dalle-2 and ChatGPT suggest that tasks previously thought to be beyond the capabilities of AI may now augment the productivity of creative media in various new ways, including through the generation of synthetic video. This research paper explores the utility of using AI-generated synthetic video to create viable educational content for online educational settings. To date, there is limited research investigating the real-world educational value of AI-generated synthetic media. To address this gap, we examined the impact of using AI-generated synthetic video in an online learning platform on both learners content acquisition and learning experience. We took a mixed-method approach, randomly assigning adult learners (n=83) into one of two micro-learning conditions, collecting pre- and post-learning assessments, and surveying participants on their learning experience. The control condition included a traditionally produced instructor video, while the experimental condition included a synthetic video with a realistic AI-generated character. The results show that learners in both conditions demonstrated significant improvement from pre- to post-learning (p<.001), with no significant differences in gains between the two conditions (p=.80). In addition, no differences were observed in how learners perceived the traditional and synthetic videos. These findings suggest that AI-generated synthetic learning videos have the potential to be a viable substitute for videos produced via traditional methods in online educational settings, making high quality educational content more accessible across the globe.

  • 4 authors
·
Apr 7, 2023

As Good As A Coin Toss: Human detection of AI-generated images, videos, audio, and audiovisual stimuli

As synthetic media becomes progressively more realistic and barriers to using it continue to lower, the technology has been increasingly utilized for malicious purposes, from financial fraud to nonconsensual pornography. Today, the principal defense against being misled by synthetic media relies on the ability of the human observer to visually and auditorily discern between real and fake. However, it remains unclear just how vulnerable people actually are to deceptive synthetic media in the course of their day to day lives. We conducted a perceptual study with 1276 participants to assess how accurate people were at distinguishing synthetic images, audio only, video only, and audiovisual stimuli from authentic. To reflect the circumstances under which people would likely encounter synthetic media in the wild, testing conditions and stimuli emulated a typical online platform, while all synthetic media used in the survey was sourced from publicly accessible generative AI technology. We find that overall, participants struggled to meaningfully discern between synthetic and authentic content. We also find that detection performance worsens when the stimuli contains synthetic content as compared to authentic content, images featuring human faces as compared to non face objects, a single modality as compared to multimodal stimuli, mixed authenticity as compared to being fully synthetic for audiovisual stimuli, and features foreign languages as compared to languages the observer is fluent in. Finally, we also find that prior knowledge of synthetic media does not meaningfully impact their detection performance. Collectively, these results indicate that people are highly susceptible to being tricked by synthetic media in their daily lives and that human perceptual detection capabilities can no longer be relied upon as an effective counterdefense.

  • 4 authors
·
Mar 25, 2024

The Necessity of Imperfection:Reversing Model Collapse via Simulating Cognitive Boundedness

Although synthetic data is widely promoted as a remedy, its prevailing production paradigm -- one optimizing for statistical smoothness -- systematically removes the long-tail, cognitively grounded irregularities that characterize human text. Prolonged training on such statistically optimal but cognitively impoverished data accelerates model collapse. This paper proposes a paradigm shift: instead of imitating the surface properties of data, we simulate the cognitive processes that generate human text. We introduce the Prompt-driven Cognitive Computing Framework (PMCSF), whose core consists of a Cognitive State Decoder (CSD) that reverse-engineers unstructured text into structured cognitive vectors, and a Cognitive Text Encoder (CTE) that re-materializes these states into text enriched with human-typical imperfections via mathematically defined Cognitive Perturbation Operators. The framework is validated through a two-stage objective evaluation pipeline. First, in cognitive codec verification, CTE text yields a Jensen-Shannon divergence of 0.0614 from human text (vs. 0.4431 for standard LLM output), passes double-blind professional media review, and achieves an intraclass correlation coefficient ICC > 0.9 for cognitive profile alignment across heterogeneous models. Second, in functional gain evaluation, isomorphic stress tests in the A-share market show that strategies incorporating CTE-generated data reduce maximum drawdown by 47.4% during the 2015 crash and deliver 8.6% Defensive Alpha, exceeding transaction costs by a factor of 33. Our findings demonstrate that modelling human cognitive limitations -- not copying surface data -- enables synthetic data with genuine functional gain, offering a viable technical pathway toward resolving the AI data-collapse crisis.

  • 1 authors
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Dec 1

AXNav: Replaying Accessibility Tests from Natural Language

Developers and quality assurance testers often rely on manual testing to test accessibility features throughout the product lifecycle. Unfortunately, manual testing can be tedious, often has an overwhelming scope, and can be difficult to schedule amongst other development milestones. Recently, Large Language Models (LLMs) have been used for a variety of tasks including automation of UIs, however to our knowledge no one has yet explored their use in controlling assistive technologies for the purposes of supporting accessibility testing. In this paper, we explore the requirements of a natural language based accessibility testing workflow, starting with a formative study. From this we build a system that takes as input a manual accessibility test (e.g., ``Search for a show in VoiceOver'') and uses an LLM combined with pixel-based UI Understanding models to execute the test and produce a chaptered, navigable video. In each video, to help QA testers we apply heuristics to detect and flag accessibility issues (e.g., Text size not increasing with Large Text enabled, VoiceOver navigation loops). We evaluate this system through a 10 participant user study with accessibility QA professionals who indicated that the tool would be very useful in their current work and performed tests similarly to how they would manually test the features. The study also reveals insights for future work on using LLMs for accessibility testing.

  • 6 authors
·
Oct 3, 2023

RealSyn: An Effective and Scalable Multimodal Interleaved Document Transformation Paradigm

After pre-training on extensive image-text pairs, Contrastive Language-Image Pre-training (CLIP) demonstrates promising performance on a wide variety of benchmarks. However, a substantial volume of non-paired data, such as multimodal interleaved documents, remains underutilized for vision-language representation learning. To fully leverage these unpaired documents, we initially establish a Real-World Data Extraction pipeline to extract high-quality images and texts. Then we design a hierarchical retrieval method to efficiently associate each image with multiple semantically relevant realistic texts. To further enhance fine-grained visual information, we propose an image semantic augmented generation module for synthetic text production. Furthermore, we employ a semantic balance sampling strategy to improve dataset diversity, enabling better learning of long-tail concepts. Based on these innovations, we construct RealSyn, a dataset combining realistic and synthetic texts, available in three scales: 15M, 30M, and 100M. Extensive experiments demonstrate that RealSyn effectively advances vision-language representation learning and exhibits strong scalability. Models pre-trained on RealSyn achieve state-of-the-art performance on multiple downstream tasks. To facilitate future research, the RealSyn dataset and pre-trained model weights are released at https://github.com/deepglint/RealSyn.

  • 9 authors
·
Feb 17 2

Synthetic continued pretraining

Pretraining on large-scale, unstructured internet text has enabled language models to acquire a significant amount of world knowledge. However, this knowledge acquisition is data-inefficient -- to learn a given fact, models must be trained on hundreds to thousands of diverse representations of it. This poses a challenge when adapting a pretrained model to a small corpus of domain-specific documents, where each fact may appear rarely or only once. We propose to bridge this gap with synthetic continued pretraining: using the small domain-specific corpus to synthesize a large corpus more amenable to learning, and then performing continued pretraining on the synthesized corpus. We instantiate this proposal with EntiGraph, a synthetic data augmentation algorithm that extracts salient entities from the source documents and then generates diverse text by drawing connections between the sampled entities. Synthetic continued pretraining using EntiGraph enables a language model to answer questions and follow generic instructions related to the source documents without access to them. If instead, the source documents are available at inference time, we show that the knowledge acquired through our approach compounds with retrieval-augmented generation. To better understand these results, we build a simple mathematical model of EntiGraph, and show how synthetic data augmentation can "rearrange" knowledge to enable more data-efficient learning.

  • 5 authors
·
Sep 11, 2024

A Multi Camera Unsupervised Domain Adaptation Pipeline for Object Detection in Cultural Sites through Adversarial Learning and Self-Training

Object detection algorithms allow to enable many interesting applications which can be implemented in different devices, such as smartphones and wearable devices. In the context of a cultural site, implementing these algorithms in a wearable device, such as a pair of smart glasses, allow to enable the use of augmented reality (AR) to show extra information about the artworks and enrich the visitors' experience during their tour. However, object detection algorithms require to be trained on many well annotated examples to achieve reasonable results. This brings a major limitation since the annotation process requires human supervision which makes it expensive in terms of time and costs. A possible solution to reduce these costs consist in exploiting tools to automatically generate synthetic labeled images from a 3D model of the site. However, models trained with synthetic data do not generalize on real images acquired in the target scenario in which they are supposed to be used. Furthermore, object detectors should be able to work with different wearable devices or different mobile devices, which makes generalization even harder. In this paper, we present a new dataset collected in a cultural site to study the problem of domain adaptation for object detection in the presence of multiple unlabeled target domains corresponding to different cameras and a labeled source domain obtained considering synthetic images for training purposes. We present a new domain adaptation method which outperforms current state-of-the-art approaches combining the benefits of aligning the domains at the feature and pixel level with a self-training process. We release the dataset at the following link https://iplab.dmi.unict.it/OBJ-MDA/ and the code of the proposed architecture at https://github.com/fpv-iplab/STMDA-RetinaNet.

  • 3 authors
·
Oct 3, 2022

BeyondWeb: Lessons from Scaling Synthetic Data for Trillion-scale Pretraining

Recent advances in large language model (LLM) pretraining have shown that simply scaling data quantity eventually leads to diminishing returns, hitting a data wall. In response, the use of synthetic data for pretraining has emerged as a promising paradigm for pushing the frontier of performance. Despite this, the factors affecting synthetic data quality remain poorly understood. In this work, we introduce BeyondWeb, a synthetic data generation framework that produces high-quality synthetic data for pretraining. BeyondWeb significantly extends the capabilities of traditional web-scale datasets, outperforming state-of-the-art synthetic pretraining datasets such as Cosmopedia and Nemotron-CC's high-quality synthetic subset (Nemotron-Synth) by up to 5.1 percentage points (pp) and 2.6pp, respectively, when averaged across a suite of 14 benchmark evaluations. It delivers up to 7.7x faster training than open web data and 2.7x faster than Nemotron-Synth. Remarkably, a 3B model trained for 180B tokens on BeyondWeb outperforms an 8B model trained for the same token budget on Cosmopedia. We also present several insights from BeyondWeb on synthetic data for pretraining: what drives its benefits, which data to rephrase and how, and the impact of model size and family on data quality. Overall, our work shows that there's no silver bullet for generating high-quality synthetic pretraining data. The best outcomes require jointly optimizing many factors, a challenging task that requires rigorous science and practical expertise. Naive approaches can yield modest improvements, potentially at great cost, while well-executed methods can yield transformative improvements, as exemplified by BeyondWeb.

SynSpill: Improved Industrial Spill Detection With Synthetic Data

Large-scale Vision-Language Models (VLMs) have transformed general-purpose visual recognition through strong zero-shot capabilities. However, their performance degrades significantly in niche, safety-critical domains such as industrial spill detection, where hazardous events are rare, sensitive, and difficult to annotate. This scarcity -- driven by privacy concerns, data sensitivity, and the infrequency of real incidents -- renders conventional fine-tuning of detectors infeasible for most industrial settings. We address this challenge by introducing a scalable framework centered on a high-quality synthetic data generation pipeline. We demonstrate that this synthetic corpus enables effective Parameter-Efficient Fine-Tuning (PEFT) of VLMs and substantially boosts the performance of state-of-the-art object detectors such as YOLO and DETR. Notably, in the absence of synthetic data (SynSpill dataset), VLMs still generalize better to unseen spill scenarios than these detectors. When SynSpill is used, both VLMs and detectors achieve marked improvements, with their performance becoming comparable. Our results underscore that high-fidelity synthetic data is a powerful means to bridge the domain gap in safety-critical applications. The combination of synthetic generation and lightweight adaptation offers a cost-effective, scalable pathway for deploying vision systems in industrial environments where real data is scarce/impractical to obtain. Project Page: https://synspill.vercel.app

  • 5 authors
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Aug 13

MetaSynth: Meta-Prompting-Driven Agentic Scaffolds for Diverse Synthetic Data Generation

Recent smaller language models such Phi-3.5 and Phi-4 rely on synthetic data generated using larger Language models. Questions remain about leveraging synthetic data for other use cases, such as adapting LLMs to specific domains. A key limitation of synthetic data is low diversity, which negatively impacts its downstream applicability for improving other models. To address this, we propose MetaSynth, a method for generating synthetic data that enhances diversity through meta-prompting, where a language model orchestrates multiple "expert" LLM agents to collaboratively generate data. Using only 25 million tokens of synthetic data generated with MetaSynth, we successfully adapt a well-trained LLM (Mistral-7B-v0.3) to two specialized domains-Finance and Biomedicine-without compromising the capabilities of the resulting model in general tasks. In addition, we evaluate the diversity of our synthetic data using seven automated metrics, and find that it approaches the diversity of LLM pre-training corpora. Continually pre-training Mistral-7B-v0.3 with MetaSynth notably outperforms the base LLM, showing improvements of up to 4.08% in Finance and 13.75% in Biomedicine. The same model shows degraded performance when trained on data generated using a template prompt, even when the template includes prior generations and varying In-Context exemplars of real data. Our findings suggest that a few million tokens of diverse synthetic data without mixing any real data, is sufficient for effective domain adaptation when using MetaSynth.

  • 5 authors
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Apr 16 2

Echo-4o: Harnessing the Power of GPT-4o Synthetic Images for Improved Image Generation

Recently, GPT-4o has garnered significant attention for its strong performance in image generation, yet open-source models still lag behind. Several studies have explored distilling image data from GPT-4o to enhance open-source models, achieving notable progress. However, a key question remains: given that real-world image datasets already constitute a natural source of high-quality data, why should we use GPT-4o-generated synthetic data? In this work, we identify two key advantages of synthetic images. First, they can complement rare scenarios in real-world datasets, such as surreal fantasy or multi-reference image generation, which frequently occur in user queries. Second, they provide clean and controllable supervision. Real-world data often contains complex background noise and inherent misalignment between text descriptions and image content, whereas synthetic images offer pure backgrounds and long-tailed supervision signals, facilitating more accurate text-to-image alignment. Building on these insights, we introduce Echo-4o-Image, a 180K-scale synthetic dataset generated by GPT-4o, harnessing the power of synthetic image data to address blind spots in real-world coverage. Using this dataset, we fine-tune the unified multimodal generation baseline Bagel to obtain Echo-4o. In addition, we propose two new evaluation benchmarks for a more accurate and challenging assessment of image generation capabilities: GenEval++, which increases instruction complexity to mitigate score saturation, and Imagine-Bench, which focuses on evaluating both the understanding and generation of imaginative content. Echo-4o demonstrates strong performance across standard benchmarks. Moreover, applying Echo-4o-Image to other foundation models (e.g., OmniGen2, BLIP3-o) yields consistent performance gains across multiple metrics, highlighting the datasets strong transferability.

  • 12 authors
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Aug 13 2