PRIMO public inputs

Blind expression inputs for the PRIMO patient-representation benchmark. datasets.yaml lists opaque ids, modalities, paths, and dimensions; clinical targets, provenance, donor ids, and cohort metadata remain private.

Each <dataset_id>/expression.h5ad stores raw counts in X, NCBI Gene IDs in var_names, and symbols in var["gene_symbols"].

• Bulk RNA files have samples as rows and opaque sample ids in obs_names.
• Single-cell RNA files are sparse and have cells as rows. Cell ids in obs_names are opaque. Their only obs column is sample_id, an opaque collection-sample id shared by cells from the same prediction unit.

Submissions are always sample-level: produce one embedding per unique obs["sample_id"], with repeated collection timepoints kept separate.

The standalone quickstart in the PRIMO evaluator Space shows the download and submission flow. Its single-cell example applies per-cell log2(CP10K + 1), mean-pools by sample_id, then runs sample-level PCA.